Drug dissolution instrument

By designing a drug dissolution device with automatic heating and cleaning functions, the problem of existing instruments lacking automatic cleaning functions is solved, and the experimental efficiency and accuracy of test results are improved.

CN222652942UActive Publication Date: 2025-03-21TIANJIN TIANFA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420585756.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-25
Publication Date
2025-03-21
Estimated Expiration
2034-03-25

AI Technical Summary

Technical Problem

The existing drug dissolution device lacks automatic cleaning function, resulting in low manual cleaning efficiency, waste of manpower, and affects the accuracy of subsequent test results.

Method used

A drug dissolution device is designed, equipped with a heating mechanism, a cleaning mechanism and a telescopic mechanism, which can automatically heat and clean the dissolution cup, including an annular heating tube, a telescopic mechanism driven by a servo motor, and a cleaning shaft, so as to achieve simultaneous heating and automatic cleaning of multiple dissolution cups.

Benefits of technology

Through automatic heating and cleaning functions, the experimental efficiency is improved, labor waste is reduced, and the cleanliness of the dissolution cup is ensured, thereby improving the accuracy of the test results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field, in particular to a medicine dissolution instrument which comprises a heat preservation shell, a heat preservation groove is formed in the top end of the heat preservation shell, a heat preservation cover is arranged at the top end of the heat preservation shell, a heating mechanism is arranged on the heat preservation shell, and a sealing bearing seat and a dissolution cup are arranged on the heat preservation groove. A telescopic mechanism is arranged at the top end of the sealing bearing seat, a supporting table is arranged on one side of the telescopic mechanism, a cleaning mechanism is arranged on the supporting table, a spray head is arranged at the bottom end of the supporting table, a hose is arranged on the spray head and extends to the top of the telescopic mechanism, and a butt joint opening is formed in the top end of the heat preservation cover. A plurality of dissolution cups are arranged in an annular array mode, a discharging valve is arranged at the bottom end of each dissolution cup, and a discharging pipe is arranged between the discharging valve and the bottom end of the heat preservation shell. According to the structure, the dissolution cups can be automatically cleaned, the cleanliness of the dissolution cups used next time is guaranteed, and therefore the experiment accuracy is guaranteed.
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Description

Technical Field

[0001] The utility model relates to the technical field of dissolution instruments, in particular to a drug dissolution instrument. Background Art

[0002] As we all know, dissolution refers to the rate and degree of dissolution of active pharmaceutical ingredients (i.e., APIs) from tablets, capsules, granules, and other preparations under specified conditions. As an important indicator for the quality evaluation of oral solid preparations, it has been increasingly used in drug research and development, production control, and marketed product supervision. The instrument used to determine the dissolution rate of a drug is a drug dissolution instrument. Existing drug dissolution instruments do not have an automatic cleaning function. After the test, multiple groups of dissolution cups usually need to be cleaned manually one by one, which is not only a waste of manpower, but also has low cleaning efficiency, thus affecting the accuracy of the next test result. Therefore, it is necessary to propose a solution to this technical problem. Utility Model Content

[0003] In order to solve the above technical problems, the utility model provides a drug dissolution instrument, including a heat-insulating shell, a heat-insulating groove is provided at the top of the heat-insulating shell, a heat-insulating cover is provided at the top of the heat-insulating shell, a heating mechanism is provided on the heat-insulating shell, a sealing bearing seat and a dissolution cup are provided on the heat-insulating groove, a telescopic mechanism is provided on the top of the sealing bearing seat, a support platform is provided on one side of the telescopic mechanism, a cleaning mechanism is provided on the support platform, a nozzle is provided at the bottom end of the support platform, a hose is provided on the nozzle, the hose extends to the top of the telescopic mechanism, a docking port is provided at the top of the heat-insulating cover, a plurality of dissolution cups are provided and arranged in a circular array, a discharge valve is provided at the bottom end of the dissolution cup, a discharge pipe is provided between the discharge valve and the bottom end of the heat-insulating shell, a drive motor is provided at the bottom end of the heat-insulating shell, and the output end of the drive motor is connected to the telescopic mechanism.

[0004] The utility model provides a drug dissolution instrument, wherein the heating mechanism comprises a heater and a heating tube, wherein the heating tube is installed in the heat preservation tank, the heating tube is in an annular structure, the heater is installed on one side of the heat preservation shell, and the heater is connected to the heating tube.

[0005] The utility model provides a drug dissolution instrument, wherein the cleaning mechanism comprises an adjusting motor and a cleaning shaft, wherein the adjusting motor is mounted on the top of the supporting platform, the output end of the adjusting motor extends to the bottom of the supporting platform, the cleaning shaft is mounted on the output end of the adjusting motor, and a cleaning plate is provided on the cleaning shaft.

[0006] The utility model provides a medicine dissolution instrument, wherein a cleaning brush is arranged on the cleaning shaft.

[0007] The utility model provides a drug dissolution instrument, wherein a plurality of heating tubes are provided.

[0008] The utility model provides a drug dissolution instrument, wherein the telescopic mechanism is a hydraulic rod.

[0009] The utility model provides a drug dissolution instrument, wherein the driving motor and the regulating motor are both servo motors.

[0010] The utility model provides a drug dissolution instrument, wherein a triangle piece is arranged between the bottom end of the support platform and the telescopic mechanism.

[0011] Compared with the prior art, the utility model has the following beneficial effects: a plurality of dissolution cups can be heated at the same time by the heating mechanism, so that a plurality of dissolution cups can be tested at the same time, thereby improving the experimental efficiency; a heat insulation effect can be achieved by the heat insulation shell and the heat insulation cover, thereby reducing power consumption; and the structure can automatically clean the dissolution cup to ensure the cleanliness of the dissolution cup when it is used next time, thereby ensuring the accuracy of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a schematic diagram of the structure of the utility model Figure 1 ;

[0013] Figure 2 This is a schematic diagram of the structure of the utility model Figure 2 ;

[0014] Figure 3 It is a structural front view of the utility model;

[0015] Figure 4 This utility model Figure 1 An enlarged top view of the structure of the middle insulation shell;

[0016] 1. Insulation shell; 2. Insulation cover; 3. Sealed bearing seat; 4. Dissolution cup; 5. Telescopic mechanism; 6. Support platform; 7. Nozzle; 8. Hose; 9. Discharge valve; 10. Discharge pipe; 11. Drive motor; 12. Heater; 13. Heating tube; 14. Adjustment motor; 15. Cleaning shaft; 16. Cleaning plate; 17. Cleaning brush. DETAILED DESCRIPTION

[0017] The following is a further detailed description of the specific implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0018] like Figures 1 to 4As shown, a drug dissolution instrument of the utility model comprises a heat-insulating shell 1, a heat-insulating groove is provided at the top of the heat-insulating shell 1, a heat-insulating cover 2 is provided at the top of the heat-insulating shell 1, a heating mechanism is provided on the heat-insulating shell 1, a sealing bearing seat 3 and a dissolution cup 4 are provided on the heat-insulating groove, a telescopic mechanism 5 is provided at the top of the sealing bearing seat 3, a support platform 6 is provided on one side of the telescopic mechanism 5, a cleaning mechanism is provided on the support platform 6, a nozzle 7 is provided at the bottom end of the support platform 6, a hose 8 is provided on the nozzle 7, and the hose 8 extends to the top of the telescopic mechanism 5, and the top of the heat-insulating cover 2 is provided with a heating mechanism ... and a telescopic mechanism 5 is provided at the top of the sealing bearing seat 3. A docking port is provided, and the dissolution cup 4 is provided with a plurality of them and arranged in a circular array. A discharge valve 9 is provided at the bottom end of the dissolution cup 4, and a discharge pipe 10 is provided between the discharge valve 9 and the bottom end of the heat-insulating shell 1. A driving motor 11 is provided at the bottom end of the heat-insulating shell 1, and the output end of the driving motor 11 is connected to the telescopic mechanism 5. In this embodiment, a plurality of dissolution cups 4 can be heated at the same time, and a plurality of dissolution cups 4 can be tested at the same time, thereby improving the experimental efficiency. Moreover, this structure can automatically clean the dissolution cup 4 to ensure the cleanliness of the dissolution cup 4 when it is used next time, thereby ensuring the accuracy of the experiment.

[0019] The utility model provides a drug dissolution instrument, wherein the heating mechanism comprises a heater 12 and a heating tube 13, wherein the heating tube 13 is installed in the heat preservation tank, wherein the heating tube 13 is annular in structure, and the heater 12 is installed on one side of the heat preservation shell 1, wherein the heater 12 is connected to the heating tube 13, and the heating tube 13 is heated by the heater 12, and a heat-conducting liquid such as water is placed in the heat preservation tank, and the heating tube 13 with an annular structure can efficiently heat a plurality of dissolution cups 4.

[0020] The utility model provides a drug dissolution instrument, wherein the cleaning mechanism comprises an adjusting motor 14 and a cleaning shaft 15, wherein the adjusting motor 14 is mounted on the top of the supporting platform 6, and the output end of the adjusting motor 14 extends to the bottom of the supporting platform 6, and the cleaning shaft 15 is mounted on the output end of the adjusting motor 14, and a cleaning plate 16 is provided on the cleaning shaft 15. The cleaning shaft 15 is rotated by the output end of the adjusting motor 14, and the cleaning plate 16 on the cleaning shaft can efficiently scrape off the impurities remaining on the inner wall of the dissolution cup 4, thereby automatically cleaning the dissolution cup 4.

[0021] In the drug dissolution instrument of the utility model, a cleaning brush 17 is provided on the cleaning shaft 15 , and the impurities on the inner wall of the dissolution cup 4 can be cleaned more efficiently by the cleaning brush 17 .

[0022] In the drug dissolution instrument of the utility model, a plurality of heating tubes 13 are provided, and the heating efficiency can be improved by using the plurality of heating tubes 13 .

[0023] In the drug dissolution instrument of the present invention, the telescopic mechanism 5 is a hydraulic rod, which has the characteristics of high precision and strong stability, so that the height of the support platform 6 can be stably raised and lowered.

[0024] In the drug dissolution instrument of the utility model, the driving motor 11 and the regulating motor 14 are both servo motors. The servo motor has the characteristic of high rotation accuracy, thereby being able to improve the rotation accuracy of the driving motor 11 and the regulating motor 14.

[0025] In the drug dissolution instrument of the utility model, a triangular piece is provided between the bottom end of the support platform 6 and the telescopic mechanism 5, and the triangular piece can make the support platform 6 more stably and reliably assembled on the telescopic mechanism 5, thereby improving the stability during cleaning.

[0026] The utility model provides a drug dissolution instrument, which, when working, tests the drug dissolution rate through the dissolution cup 4, heats the heat preservation tank through the heating mechanism, pours a heat-conducting liquid, such as water, into the heat preservation tank, and then plays a heat preservation and heat insulation effect through the heat preservation cover 2 and the heat preservation shell 1, reduces heat loss, realizes the heating operation of multiple dissolution cups 4, ensures that the dissolution process of multiple dissolution cups 4 is carried out under standard conditions, and can realize the dissolution test of multiple dissolution cups 4 at the same time. After the test is completed, the discharge valve 9 is opened, so that the liquid in the dissolution cup 4 is discharged through the discharge pipe 10, and can be automatically discharged to the next detection process, which is convenient for personnel to detect the liquid, avoids errors caused by manual operation, and improves the accuracy of the experiment. Liquid impurities will remain in the dissolution cup 4. At this time, the telescopic mechanism 5 is rotated by controlling the output end of the drive motor 11, and the telescopic mechanism 5 can be stably stably in the heat preservation tank through the sealing bearing seat 3. The fixed rotation and the sealed bearing seat 3 can effectively prevent water from penetrating into the internal components, align the support platform 6 with the bottom of the dissolution cup 4, and then shrink the telescopic mechanism 5 to move the support platform 6 downward, so that the cleaning mechanism extends into the dissolution cup 4, and then the dissolution cup 4 is cleaned by the cleaning mechanism, and the hose 8 extends from the docking port at the top of the thermal insulation cover 2 to the outside, and then the personnel use the water supply mechanism to connect the hose 8, so that the nozzle 7 sprays water, and the impurities are washed away while cleaning, so that the cleaning is more thorough, and then a drainage pipe is placed at one end of the discharge pipe 10, and the impurities are discharged through the discharge valve 9, and then the telescopic mechanism 5 is extended to reset the support platform 6, and then the telescopic mechanism 5 is rotated by the output end of the driving motor 11 to align the support platform 6 with other dissolution cups 4 that need to be cleaned, so as to facilitate the automatic cleaning of the dissolution cup 4 and ensure the cleanliness of the dissolution cup 4 when it is used next time, thereby ensuring the accuracy of the experiment.

[0027] The installation, connection or setting methods of the drug dissolution instrument of the utility model are all common mechanical methods, and any method that can achieve its beneficial effects can be implemented; technicians in this industry only need to install and operate it according to the accompanying instruction manual.

[0028] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A drug dissolution apparatus, comprising a heat-insulating housing (1), characterized in that: The top of the heat-insulating shell (1) is provided with a heat-insulating groove, the top of the heat-insulating shell (1) is provided with a heat-insulating cover (2), the heat-insulating shell (1) is provided with a heating mechanism, the heat-insulating groove is provided with a sealing bearing seat (3) and a dissolution cup (4), the top of the sealing bearing seat (3) is provided with a telescopic mechanism (5), one side of the telescopic mechanism (5) is provided with a support platform (6), the support platform (6) is provided with a cleaning mechanism, the bottom of the support platform (6) is provided with a nozzle (7), the nozzle (7) is provided with a A hose (8) is provided, the hose (8) extending to the top of the telescopic mechanism (5), a docking port is provided at the top of the thermal insulation cover (2), a plurality of dissolution cups (4) are provided and arranged in a ring array, a discharge valve (9) is provided at the bottom end of the dissolution cup (4), a discharge pipe (10) is provided between the discharge valve (9) and the bottom end of the thermal insulation shell (1), a drive motor (11) is provided at the bottom end of the thermal insulation shell (1), and the output end of the drive motor (11) is connected to the telescopic mechanism (5).

2. A drug dissolution apparatus according to claim 1, characterized in that: The heating mechanism comprises a heater (12) and a heating tube (13); the heating tube (13) is installed in the heat preservation tank; the heating tube (13) is an annular structure; the heater (12) is installed on one side of the heat preservation shell (1); and the heater (12) is connected to the heating tube (13).

3. A drug dissolution apparatus according to claim 2, characterized in that: The cleaning mechanism comprises an adjusting motor (14) and a cleaning shaft (15); the adjusting motor (14) is mounted on the top of the supporting platform (6); the output end of the adjusting motor (14) extends to the bottom of the supporting platform (6); the cleaning shaft (15) is mounted on the output end of the adjusting motor (14); and a cleaning plate (16) is provided on the cleaning shaft (15).

4. A drug dissolution apparatus according to claim 3, characterized in that: The cleaning shaft (15) is provided with a cleaning brush (17).

5. A drug dissolution apparatus according to claim 4, characterized in that: The heating tubes (13) are provided in plurality.

6. A drug dissolution apparatus according to claim 5, characterized in that: The telescopic mechanism (5) is a hydraulic rod.

7. A drug dissolution apparatus according to claim 6, characterized in that: The driving motor (11) and the regulating motor (14) are both servo motors.

8. A drug dissolution apparatus according to claim 7, characterized in that: A triangular piece is provided between the bottom end of the support platform (6) and the telescopic mechanism (5).