Immune globulin freeze-drying equipment

Abstract

The utility model provides immune globulin freeze-drying equipment, which relates to the technical field of protein freeze-drying, and comprises a vacuum box, the surface of the vacuum box is rotatably connected with a box door, the inner wall of the vacuum box is fixedly provided with a refrigeration assembly, the inner wall of the vacuum box is rotatably connected with a rotating shaft, the surface of the rotating shaft is fixedly provided with a placing frame, and the placing frame is fixedly provided with an opening. A worm wheel is fixedly installed at the bottom end of the rotating shaft, a motor is fixedly installed on the bottom face of the vacuum box, a worm is installed at the output end of the motor, and a connecting rod is fixedly installed at the top end of the rotating shaft. The worm, the worm gear and the rotating shaft are driven by the motor, so that the placing frame can rotate, the rotating design ensures that immune globulin can be uniformly heated and freeze-dried, the uniformity and the quality of the freeze-drying effect are improved, meanwhile, the connecting rod and the top plate are driven to rotate the reflector when the rotating shaft rotates, the working state is visually indicated, and the working efficiency is improved. And a worker can be reminded that the equipment is running.

Description

Technical Field

[0001] This utility model relates to the field of protein freeze-drying technology, and in particular to an immunoglobulin freeze-drying device. Background Technology

[0002] Vacuum freeze-drying technology is a novel drying method that freezes water-containing materials into solids and utilizes the sublimation properties of water under low temperature and low pressure conditions to dehydrate the materials at low temperatures. Because vacuum freeze-drying is carried out in a low-temperature, low-oxygen environment, most biological reactions cease, and no liquid water is present during the process; the water sublimates directly in a solid state, maximizing the preservation of the material's original structure and shape. This results in high-quality dried products with both excellent appearance and internal quality. Immunoglobulins require this freeze-drying process.

[0003] Publication No. CN218583583U discloses a vacuum freeze-drying device for silk protein, including a vacuum chamber. A fixed box is fixed to the bottom of the vacuum chamber. A refrigeration assembly is arranged inside the fixed box. The refrigeration assembly includes a compressor, a condenser, and an evaporator. The compressor and condenser are arranged inside the fixed box, and the evaporator is arranged at the bottom of the vacuum chamber. The compressor, condenser, and evaporator are connected to form a closed loop through pipes. A vacuum pump is fixed to the right side of the vacuum chamber, and the air inlet of the vacuum pump is connected to the vacuum chamber through an air inlet pipe. The vacuum chamber is connected to a vacuum pump, with a gas duct connected to the outlet of the vacuum pump. The end of the gas duct away from the vacuum pump is connected to a chamber body fixed to the back of the vacuum chamber. A return pipe is connected to the side of the chamber body away from the gas duct, and the other end of the return pipe is connected to the vacuum chamber. A regulating valve is installed in the middle section of the gas duct. A fixing frame is fixed inside the chamber body, and a reverse osmosis filter membrane is installed inside the fixing frame. An adjusting component is installed inside the chamber body. A microwave heater is installed on the back of the vacuum chamber's inner cavity, and a temperature and humidity sensor is installed inside the vacuum chamber. While this type of freeze-drying equipment simplifies the drying process and reduces costs, its fixed placement means that some parts are exposed to the heat source for longer periods, while others are exposed for relatively less. This uneven heating directly affects the uniformity of the freeze-drying effect and the quality of the final product. Specifically, uneven heating may cause some immunoglobulins to over-dry and lose activity, or some areas may not be completely freeze-dried, containing excessive residual moisture, both of which can negatively impact product stability and shelf life. Therefore, improvements are needed. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing an immunoglobulin freeze-drying device.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: an immunoglobulin freeze-drying device, comprising a vacuum chamber, a door rotatably connected to the surface of the vacuum chamber, a refrigeration component fixedly installed on the inner wall of the vacuum chamber, a rotating shaft rotatably connected to the inner wall of the vacuum chamber, a placement frame fixedly installed on the surface of the rotating shaft, a worm gear fixedly installed at the bottom end of the rotating shaft, a motor fixedly installed on the bottom surface of the vacuum chamber, a worm gear installed at the output end of the motor, a connecting rod fixedly installed at the top end of the rotating shaft, a top plate fixedly installed at the top end of the connecting rod, and a reflector fixedly installed on the surface of the top plate.

[0006] Preferably, the reflectors are symmetrically distributed on the surface of the top plate, and the worm gear meshes with the worm.

[0007] Preferably, the vacuum chamber is fixedly mounted with support legs on its bottom surface, and the support legs are evenly distributed at the four corners of the bottom surface of the vacuum chamber. This provides stable support for the vacuum chamber.

[0008] Preferably, the placement frames are arranged at equal intervals on the surface of the rotating shaft, and the surface of the vacuum chamber has an opening the same size as the chamber door. This allows for the placement of more immunoglobulins.

[0009] Preferably, the surface of the cabinet door is provided with an observation mechanism, which includes an observation window. The observation window is fixedly installed on the surface of the cabinet door, and a rotating rod is provided through the surface of the observation window. Side plates are fixedly installed at both ends of the rotating rod, and a brush plate is fixedly installed on the side plate near the observation window. This allows for convenient observation of the freeze-drying process.

[0010] Preferably, the rotating rod is rotatably connected to the observation window.

[0011] Preferably, the brush plate is made of sponge, and the brush plate is in contact with the observation window. This can improve the cleaning effect.

[0012] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0013] 1. This utility model uses a motor to drive a worm gear, worm wheel, and rotating shaft, enabling the placement frame to rotate. The rotating design ensures that the immunoglobulins are heated and freeze-dried evenly, thereby improving the uniformity and quality of the freeze-drying effect. At the same time, the rotating shaft drives the connecting rod and top plate to rotate the reflector, which not only provides a visual indication of the working status but also reminds the staff that the equipment is running, avoiding adverse consequences caused by accidentally opening the box door and enhancing operational safety.

[0014] 2. In this utility model, staff can observe the working conditions inside the vacuum chamber in real time through the observation window. This helps them to judge in a timely and accurate manner whether the freeze-drying process is proceeding normally. When stains or fog appear on the surface of the observation window, staff only need to push the side plate to drive the brush plate to clean the front and back of the observation window. This improves the ease of use and maintenance efficiency of the equipment, reduces blurred vision caused by stains or fog, and ensures that staff can always clearly observe the inside of the vacuum chamber. Furthermore, by pushing the side plate, the front and back of the observation window can be cleaned at the same time, which not only improves cleaning efficiency but also ensures the clarity of observation. Attached Figure Description

[0015] Figure 1 This utility model provides a front view of an immunoglobulin freeze-drying device;

[0016] Figure 2 A bottom view of an immunoglobulin freeze-drying device is provided for this utility model;

[0017] Figure 3 This utility model provides a front view of an immunoglobulin freeze-drying device;

[0018] Figure 4 A top view of an immunoglobulin freeze-drying device is provided for this utility model;

[0019] Figure 5 This invention provides an immunoglobulin freeze-drying device. Figure 4 Enlarged view of point A in the middle.

[0020] Legend:

[0021] 1. Vacuum chamber; 2. Chamber door; 3. Refrigeration unit; 4. Rotating shaft; 5. Placement frame; 6. Worm gear; 7. Motor; 8. Worm; 9. Connecting rod; 10. Top plate; 11. Reflector; 12. Support leg; 13. Observation window; 14. Rotating rod; 15. Side plate; 16. Brush plate. Detailed Implementation

[0022] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0023] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0024] Example 1

[0025] Please see Figure 1-5 This utility model provides a technical solution: an immunoglobulin freeze-drying device, including a vacuum chamber 1. Support legs 12, made of high-strength steel, are fixedly installed on the bottom surface of the vacuum chamber 1 by welding to stably support it. The support legs 12 are evenly distributed at the four corners of the bottom surface of the vacuum chamber 1, providing balance and stability for the device. A door 2 is hinged to the surface of the vacuum chamber 1 for easy opening and closing while ensuring good sealing. An opening of the same size as the door 2 is provided on the surface of the vacuum chamber 1 for easy insertion and removal of materials. A refrigeration component 3 is bolted to the inner wall of the vacuum chamber 1. The refrigeration component 3 uses advanced semiconductor refrigeration technology to achieve rapid and uniform freezing. A rotating shaft 4 is rotatably connected to the inner wall of the vacuum chamber 1 via bearings to ensure rotational flexibility and stability. A placement frame 5, made of aluminum alloy, is fixedly installed on the surface of the rotating shaft 4 by welding. The placement frame 5 is lightweight and has good thermal conductivity. The placement frames 5 are arranged at equal intervals on the surface of the rotating shaft 4 to maximize space utilization and ensure the freeze-drying effect.

[0026] Please see Figure 1-5 A worm gear 6 is fixedly mounted at the bottom end of the rotating shaft 4 via a key connection. The worm gear 6 and the worm 8 fit tightly together, resulting in high power transmission efficiency. A motor 7 is bolted to the bottom surface of the vacuum chamber 1, providing stable and reliable power. A worm 8 is mounted at the output end of the motor 7. The worm 8 is made of high-strength steel, which is wear-resistant and has a long service life. The worm gear 6 meshes with the worm 8 to achieve efficient power transmission. A connecting rod 9 is fixedly mounted at the top end of the rotating shaft 4 by welding. The connecting rod 9 is made of stainless steel, which has good strength and corrosion resistance. A top plate 10 is bolted to the top end of the connecting rod 9. Reflectors 11 are symmetrically distributed on the surface of the top plate 10 to achieve 360-degree visibility.

[0027] Example 2

[0028] Please see Figure 4-5 The surface of the door 2 is equipped with an observation mechanism, including an observation window 13. The observation window 13 is fixedly installed on the surface of the door 2 and is made of high-strength, transparent special glass, which can withstand the pressure and temperature changes that may occur inside the vacuum chamber 1 while maintaining a clear view. To ensure continuous observation, a rotating rod 14 is installed through the surface of the observation window 13. The rotating rod 14 is rotatably connected to the observation window 13 through bearings, ensuring the flexibility and stability of rotation. Side plates 15 are fixedly installed at both ends of the rotating rod 14. A brush plate 16 is fixedly installed on the side of the side plate 15 near the observation window 13. The brush plate 16 is made of soft sponge with good cleaning ability. It fits tightly against the observation window 13 to ensure that stains and fog on the window surface can be effectively removed when rotating.

[0029] Working principle: When freeze-drying immunoglobulins, simply open the door 2, place the immunoglobulins into the placement frame 5, close the door 2, and then freeze them using the refrigeration unit 3. After freezing, heating is performed to freeze-dry the immunoglobulins. The motor 7 drives the worm gear 8 to rotate, which in turn drives the meshing worm wheel 6. The worm wheel 6 then drives the rotating shaft 4, which in turn drives the placement frame 5. This ensures uniform drying of the immunoglobulins, improving the freeze-drying effect. Simultaneously, the rotation of the rotating shaft 4 also drives the connecting rod 9 to rotate, connecting... Rod 9 then drives top plate 10 to rotate, which in turn drives reflector 11 to rotate. The rotating reflector 11 serves as a reminder to staff that the vacuum chamber 1 is in the process of freeze-drying, preventing accidental opening. This invention uses motor 7 to drive worm gear 8, worm wheel 6, and rotating shaft 4, enabling the placement frame 5 to rotate. This rotational design ensures that immunoglobulins are heated and freeze-dried evenly, thus improving the uniformity and quality of the freeze-drying effect. Simultaneously, the rotation of shaft 4 drives connecting rod 9 and top plate 10, causing reflector 11 to rotate. This not only provides a visual indication of the working status but also reminds staff that the equipment is in operation. This design avoids the adverse consequences of accidentally opening the chamber door 2, enhancing operational safety. Simultaneously, operators can observe the internal workings of the vacuum chamber 1 through the observation window 13 to determine if freeze-drying is proceeding normally. When there are stains or fog on the surface of the observation window 13, operators simply need to push the side plate 15, which in turn rotates the rotating rod 14. The rotating rod 14 then rotates another set of side plates 15, causing both side plates 15 to rotate the brush plate 16, allowing for cleaning of both sides of the observation window 13. In this invention, operators can observe the vacuum chamber 1 in real time through the observation window 13. The operation inside the empty chamber 1 can be monitored, which helps them to judge in a timely and accurate manner whether the freeze-drying process is proceeding normally. When stains or fog appear on the surface of the observation window 13, the staff only needs to push the side plate 15 to drive the brush plate 16 to clean the front and back of the observation window 13. This improves the ease of use and maintenance efficiency of the equipment, reduces the blurring of vision caused by stains or fog, and ensures that the staff can always clearly observe the inside of the vacuum chamber 1. By pushing the side plate 15, the front and back of the observation window 13 can be cleaned at the same time, which not only improves the cleaning efficiency but also ensures the clarity of observation.

[0030] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. An immunoglobulin lyophilization apparatus comprising a vacuum chamber (1), characterized in that: The vacuum chamber (1) is rotatably connected to a door (2). A refrigeration component (3) is fixedly installed on the inner wall of the vacuum chamber (1). A rotating shaft (4) is rotatably connected to the inner wall of the vacuum chamber (1). A placement frame (5) is fixedly installed on the surface of the rotating shaft (4). A worm gear (6) is fixedly installed at the bottom end of the rotating shaft (4). A motor (7) is fixedly installed on the bottom surface of the vacuum chamber (1). A worm gear (8) is installed at the output end of the motor (7). A connecting rod (9) is fixedly installed at the top end of the rotating shaft (4). A top plate (10) is fixedly installed at the top end of the connecting rod (9). A reflector (11) is fixedly installed on the surface of the top plate (10).

2. The immunoglobulin lyophilization apparatus of claim 1, wherein: The reflectors (11) are symmetrically distributed on the surface of the top plate (10), and the worm gear (6) meshes with the worm (8).

3. The immunoglobulin lyophilization apparatus of claim 1, wherein: The bottom surface of the vacuum chamber (1) is fixedly equipped with support legs (12), which are evenly distributed at the four corners of the bottom surface of the vacuum chamber (1).

4. The immunoglobulin lyophilization apparatus of claim 1, wherein: The placement frames (5) are arranged at equal distances on the surface of the rotating shaft (4), and the surface of the vacuum box (1) has an opening of the same size as the box door (2).

5. The immunoglobulin lyophilization apparatus of claim 1, wherein: The surface of the box door (2) is provided with an observation mechanism, which includes an observation window (13). The observation window (13) is fixedly installed on the surface of the box door (2). A rotating rod (14) is provided through the surface of the observation window (13). Side plates (15) are fixedly installed at both ends of the rotating rod (14). A brush plate (16) is fixedly installed on the side of the side plate (15) near the observation window (13).

6. The immunoglobulin lyophilization apparatus of claim 5, wherein: The rotating rod (14) is rotatably connected to the observation window (13).

7. The immunoglobulin lyophilization apparatus of claim 5, wherein: The brush plate (16) is made of sponge and is attached to the observation window (13).

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