Multi-stage fine filtration device for biological enzyme preparation

Abstract

The utility model relates to the technical field of filtering devices, and particularly discloses a multi-stage fine filtering device for a biological enzyme preparation, which comprises a pre-filter, a coarse filter and a fine filter which are arranged in sequence, a steam filter is arranged between the coarse filter and the fine filter; wherein each of the pre-filter, the coarse filter and the fine filter comprises a base, a cover body arranged at the top of the base, a locking piece for fixing the cover body at the top of the base and a microporous membrane filter element mounted at the top of the base and arranged in the cover body, and an input port communicated with an input cavity in the base is formed in the top of the base; according to the utility model, the series design of pre-filtration, rough filtration, steam sterilization and fine filtration reduces the impurity load step by step, the steam filter is arranged between the rough filtration and the fine filtration, and the sterilized liquid is subjected to fine filtration, so that the filtration precision is improved, the enzyme activity is prevented from being damaged due to incomplete sterilization or high temperature, the sterilization and filtration are synergistic, the sterility is ensured, and the enzyme activity is protected at the same time.

Description

Technical Field

[0001] This utility model relates to the field of filtration device technology, specifically a multi-stage fine filtration device for biological enzyme preparations. Background Technology

[0002] After the biological enzyme solution produced by the enterprise is coarsely filtered to obtain crude enzyme solution, it needs to undergo fine filtration and sterilization to obtain biological enzyme preparation products that meet the technical standards. The existing filtration system cannot meet the requirements of filtration precision and sterilization, and therefore the filtered enzyme preparation products cannot meet the technical standards and sterilization requirements, affecting the quality of the products.

[0003] For example, a multi-stage filtration device for biological enzyme preparation stock solution disclosed in the existing announcement number CN221618755U includes: a fixed half-tank and a movable tank cover, the movable tank cover being hinged to one side of the fixed half-tank; a dispersion plate, the dispersion plate being fixedly installed inside the fixed half-tank near the top, the dispersion plate having a horizontally closed area in the middle, and dispersion through holes on the outer side of the closed area; a sieve plate, the sieve plate being installed at intervals at the bottom of the dispersion plate and fixedly connected to the fixed half-tank; and a stirring shaft, the stirring shaft being installed inside the fixed half-tank and passing through the dispersion plate and the middle of the sieve plate via a water-sealed bearing, filtering the enzyme preparation stock solution through the sieve plate, the sieve plate having three sets, the sieve holes in the notched filter paper layer of the three sets of sieve plates being, from top to bottom, fast holes, medium-speed holes and slow holes.

[0004] The aforementioned filtration device uses three sets of filter plates for filtration, but lacks a multi-stage gradient filtration design. This results in insufficient interception of large particulate impurities, easy clogging of subsequent fine filter cartridges, low filtration efficiency, and inability to meet the requirements for filtration precision and sterilization. The final product may contain residual microparticles or microorganisms, necessitating improvement. To address these issues, a multi-stage fine filtration device for biological enzyme preparations is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a multi-stage fine filtration device for biological enzyme preparations to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A multi-stage fine filtration device for biological enzyme preparations includes a pre-filter, a coarse filter, and a fine filter arranged sequentially; a steam filter is provided between the coarse filter and the fine filter.

[0008] The pre-filter, coarse filter, and fine filter each include a base, a cover set on top of the base, a locking device for fixing the cover to the top of the base, and a microporous membrane filter element installed on top of the base and inside the cover. The top of the base has an inlet port communicating with the input cavity inside the base, the bottom of the base is connected to an inlet pipe communicating with the input cavity, the top of the base has an outlet port, the bottom of the microporous membrane filter element is connected to a connector that mates with the outlet port, the outlet port communicates with the output cavity inside the base, and the bottom of the base is installed with an outlet pipe communicating with the output cavity.

[0009] The microporous membrane filter element is provided with a positioning plate at the top, and the cover is provided with a detection tube that can press the positioning plate at the top;

[0010] The steam filter outlet is located between the liquid inlet pipe and the liquid outlet pipe.

[0011] In one alternative: the steam filter includes a steam filter body and a delivery pipe connected to the steam outlet end of the steam filter body, a control valve is installed on the delivery pipe, and the end of the coarse filter away from the control valve is connected to an installation pipe.

[0012] In one alternative: the end of the inlet pipe away from the base is connected to a detection valve, the mounting pipe is connected between the detection valve and the outlet pipe, and the bottom of the inlet pipe near the base is also connected to a waste pipe.

[0013] In one alternative: the positioning disk has a fixing hole that can be inserted into the top of the microporous membrane filter element, the inner diameter of the fixing hole is smaller than the outer diameter of the microporous membrane filter element, the positioning disk has a through hole at the center, and the positioning screw that can pass through the through hole is installed at the center of the top of the base.

[0014] In one alternative: the positioning plate is provided with two sets of detection holes communicating with the detection tube, the top of the cover is provided with a detection cavity communicating with the detection tube, and the top of the cover is equipped with a pressure detection component corresponding to the detection cavity.

[0015] In one alternative: the top of the base is further provided with a protective component; the protective component includes a sealing plate and a pressure plate, the angle between the sealing plate and the pressure plate is 90°-120°, a rotating block is fixedly connected to the top of the base, the connection between the sealing plate and the pressure plate is rotatably connected to the rotating block, and the end of the pressure plate away from the sealing plate contacts the bottom of the cover.

[0016] In one alternative embodiment: the locking element includes a rotating seat fixedly connected to the bottom of the outer ring of the base, the rotating seat being rotatably connected to a rotating rod, the rotating rod being threadedly connected to a threaded sleeve, a limiting block being rotatably connected to the threaded sleeve, and one side of the limiting block contacting the bottom outer ring of the cover.

[0017] In one alternative: the pore size of the microporous membrane filter element in the pre-filter, coarse filter and fine filter gradually decreases.

[0018] Compared with the prior art, the beneficial effects of this utility model are:

[0019] The series design of pre-filtration, coarse filtration, steam sterilization and fine filtration in this utility model reduces the impurity load step by step. The steam filter is placed between the coarse filter and the fine filter. After sterilization, the liquid is then subjected to fine filtration to improve the filtration accuracy and avoid incomplete sterilization or damage to enzyme activity by high temperature. Sterilization and filtration work together to ensure sterility while protecting enzyme activity. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of this utility model.

[0021] Figure 2 This is a schematic diagram of the steam filter in this utility model.

[0022] Figure 3 This is a schematic diagram of the structure of the connecting components on the base and the cover in this utility model.

[0023] Figure 4 This is a schematic diagram showing the disassembled structure of the microporous membrane filter element and the base in this utility model.

[0024] Figure 5 This is a schematic diagram of the structure of the cover in this utility model.

[0025] Figure 6 This is a partial structural schematic diagram of the present invention.

[0026] In the diagram: 1. Pre-filter; 2. Coarse filter; 3. Fine filter; 4. Steam filter; 41. Steam filter body; 42. Delivery pipe; 43. Control valve; 44. Mounting pipe; 11. Base; 12. Cover; 13. Inlet pipe; 131. Detection valve; 132. Waste pipe; 14. Outlet pipe; 15. Microporous membrane filter element; 16. Positioning plate; 17. Positioning screw; 18. Protective component; 19. Locking component; 111. Input port; 112. Output port; 121. Pressure detection component; 122. Detection pipe; 151. Connecting joint; 161. Fixing hole; 162. Detection hole; 163. Perforation; 181. Sealing plate; 182. Pressure plate; 183. Rotating block; 191. Rotating seat; 192. Rotating rod; 193. Limiting block; 194. Threaded sleeve. Detailed Implementation

[0027] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figures 1-6 In this embodiment, a multi-stage fine filtration device for biological enzyme preparations includes a pre-filter 1, a coarse filter 2, and a fine filter 3 arranged sequentially; a steam filter 4 is provided between the coarse filter 2 and the fine filter 3.

[0030] The pre-filter 1, coarse filter 2, and fine filter 3 each include a base 11, a cover 12 disposed on the top of the base 11, a locking member 19 for fixing the cover 12 to the top of the base 11, and a microporous membrane filter element 15 disposed on the top of the base 11 and inside the cover 12. The top of the base 11 is provided with an inlet port 111 communicating with the input cavity inside the base 11. The bottom of the base 11 is connected to an inlet pipe 13 communicating with the input cavity. The top of the base 11 is provided with an outlet port 112. The bottom of the microporous membrane filter element 15 is connected to a connector 151 that mates with the outlet port 112. The outlet port 112 communicates with the output cavity inside the base 11. The bottom of the base 11 is provided with an outlet pipe 14 communicating with the output cavity.

[0031] The microporous membrane filter element 15 is provided with a positioning disk 16 on the top, and the cover 12 is provided with a detection tube 122 that can press the positioning disk 16 on the top.

[0032] The steam filter 4 is located between the liquid inlet pipe 13 and the liquid outlet pipe 14;

[0033] The pore size of the microporous membrane filter element 15 in the pre-filter 1, coarse filter 2 and fine filter 3 gradually decreases;

[0034] Using the above scheme, the liquid biological enzyme preparation enters the pre-filter 1 through the inlet pipe 13 for filtration. Then, the liquid flows through the coarse filter 2 and the fine filter 3 in sequence for filtration, completing the fine filtration and obtaining a high-purity enzyme preparation. At the same time, steam is introduced before the final filtration stage to sterilize the liquid after coarse filtration or maintain a suitable temperature to prevent enzyme inactivation and avoid microbial contamination.

[0035] Please see Figure 2 The steam filter 4 includes a steam filter body 41 and a delivery pipe 42 connected to the steam outlet end of the steam filter body 41. A control valve 43 is installed on the delivery pipe 42. The coarse filter 2 is connected to an installation pipe 44 at the end away from the control valve 43. The steam filter 4 injects steam into the liquid through the delivery pipe 42, and the control valve 43 regulates the steam flow rate.

[0036] Please see Figure 3 The inlet pipe 13 is connected to the detection valve 131 at the end away from the base 11. The mounting pipe 44 is connected between the detection valve 131 and the outlet pipe 14. The bottom of the inlet pipe 13 near the base 11 is also connected to the waste liquid pipe 132. Specifically, the waste liquid pipe 132 can be used to discharge waste liquid, and can be connected to external pipes and valves, for example, for cleaning pipes to remove impurities; or to recover a small amount of material generated by each stage filter that does not enter the next stage and then return it to the conveying system to improve the yield of the filtration system.

[0037] Please see Figure 4 The positioning disk 16 is provided with a fixing hole 161 that can be inserted into the top of the microporous membrane filter element 15. The inner diameter of the fixing hole 161 is smaller than the outer diameter of the microporous membrane filter element 15. The positioning disk 16 is provided with a through hole 163 at the center. The positioning screw 17 that can pass through the through hole 163 is installed at the center of the top of the base 11. Specifically, in actual use, a nut that is threaded to the positioning screw 17 can be selected. When the positioning disk 16 is placed on the top of the microporous membrane filter element 15, the nut can be used to rotate on the positioning screw 17 to fix the position of the positioning disk 16.

[0038] Please see Figure 4 The positioning plate 16 is provided with two sets of detection holes 162 communicating with the detection tube 122. The top of the cover 12 is provided with a detection cavity communicating with the detection tube 122. The top of the cover 12 is equipped with a pressure detection component 121 corresponding to the detection cavity. Specifically, when the cover 12 is installed, the detection tube 122 presses against the positioning plate 16 for limiting, and at the same time, the detection tube 122 connects with the detection hole 162 to facilitate the pressure detection component 121 to detect the pressure inside the filter.

[0039] Please see Figure 6The base 11 is also provided with a protective component 18 on its top. The protective component 18 includes a sealing plate 181 and a pressure plate 182. The angle between the sealing plate 181 and the pressure plate 182 is 90°-120°. A rotating block 183 is fixedly connected to the top of the base 11. The connection between the sealing plate 181 and the pressure plate 182 is rotatably connected to the rotating block 183. The end of the pressure plate 182 away from the sealing plate 181 contacts the bottom of the cover 12. When the cover 12 is installed, the sealing plate 181 can be flipped away from the inlet 111. After that, when the cover 12 is installed, the bottom presses and limits the pressure plate 182, restricting the rotation of the sealing plate 181. The inlet 111 can be used for normal input. When the cover 12 is disassembled for cleaning, before disassembling the microporous membrane filter element 15, the sealing plate 181 can be flipped to block the inlet 111, reducing the number of parts and residues falling into the input cavity.

[0040] Please see Figure 1 and Figure 6 The number of locking components 19 can be set according to actual needs, such as the common 8 sets. Each locking component 19 includes a rotating seat 191 fixedly connected to the bottom of the outer ring of the base 11. The rotating seat 191 is rotatably connected to a rotating rod 192. The rotating rod 192 is threadedly connected to a threaded sleeve 194. A limiting block 193 is rotatably connected to the threaded sleeve 194. One outer extension of the limiting block 193 contacts the bottom outer ring of the cover 12. When the cover 12 is placed on the base 11, rotating the rotating rod 192 causes the outer extension of the limiting block 193 to align with the bottom outer ring of the cover 12. Tightening the threaded sleeve 194 causes the limiting block 193 to move downwards. Figure 1 As shown, the limiting block 193 presses and fixes the cover 12.

[0041] The working principle of this invention is as follows: the biological enzyme preparation liquid enters the pre-filter 1 through the inlet pipe 13 for filtration, and then the liquid flows through the coarse filter 2 and the fine filter 3 in sequence for filtration to complete fine filtration and obtain a high-purity enzyme preparation. At the same time, steam is introduced before the final filtration to sterilize the liquid after coarse filtration or maintain a suitable temperature to prevent enzyme inactivation and avoid microbial contamination.

[0042] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A multi-stage fine filtration device for biological enzyme preparations, comprising a pre-filter (1), a coarse filter (2), and a fine filter (3) arranged sequentially; characterized in that: A steam filter (4) is provided between the coarse filter (2) and the fine filter (3); The pre-filter (1), coarse filter (2) and fine filter (3) each include a base (11), a cover (12) set on the top of the base (11), a locking member (19) for fixing the cover (12) to the top of the base (11), and a microporous membrane filter element (15) installed on the top of the base (11) and set inside the cover (12). The top of the base (11) is provided with an inlet port (111) communicating with the inlet cavity inside the base (11). The bottom of the base (11) is connected with an inlet pipe (13) communicating with the inlet cavity. The top of the base (11) is provided with an outlet port (112). The bottom of the microporous membrane filter element (15) is connected with a connector (151) that connects to the outlet port (112). The outlet port (112) communicates with the outlet cavity inside the base (11). The bottom of the base (11) is installed with an outlet pipe (14) communicating with the outlet cavity. The microporous membrane filter element (15) is provided with a positioning plate (16) on the top, and the cover (12) is provided with a detection tube (122) that can press the positioning plate (16) on the top. The steam filter (4) has its steam outlet located between the liquid inlet pipe (13) and the liquid outlet pipe (14).

2. The multi-stage fine filtration device for biological enzyme preparations according to claim 1, characterized in that: The steam filter (4) includes a steam filter body (41) and a delivery pipe (42) connected to the steam outlet end of the steam filter body (41). A control valve (43) is installed on the delivery pipe (42). The coarse filter (2) is connected to an installation pipe (44) at the end away from the control valve (43).

3. The multi-stage fine filtration device for biological enzyme preparations according to claim 2, characterized in that: The inlet pipe (13) is connected to the detection valve (131) at the end away from the base (11), and the mounting pipe (44) is connected between the detection valve (131) and the outlet pipe (14). The bottom of the inlet pipe (13) near the base (11) is also connected to the waste pipe (132).

4. The multi-stage fine filtration device for biological enzyme preparations according to claim 1, characterized in that: The positioning disk (16) is provided with a fixing hole (161) that can be inserted into the top of the microporous membrane filter element (15). The inner diameter of the fixing hole (161) is smaller than the outer diameter of the microporous membrane filter element (15). The positioning disk (16) is provided with a through hole (163) at the center. The positioning screw (17) that can pass through the through hole (163) is installed at the center of the top of the base (11).

5. The multi-stage fine filtration device for biological enzyme preparations according to claim 4, characterized in that: The positioning plate (16) is provided with two sets of detection holes (162) communicating with the detection tube (122), the top of the cover (12) is provided with a detection cavity communicating with the detection tube (122), and the top of the cover (12) is equipped with a pressure detection component (121) corresponding to the detection cavity.

6. The multi-stage fine filtration device for biological enzyme preparations according to claim 1, characterized in that: The base (11) is also provided with a protective component (18) on top; the protective component (18) includes a sealing plate (181) and a pressure plate (182), the angle between the sealing plate (181) and the pressure plate (182) is 90°-120°, the top of the base (11) is fixedly connected to a rotating block (183), the connection between the sealing plate (181) and the pressure plate (182) is rotatably connected to the rotating block (183), and the end of the pressure plate (182) away from the sealing plate (181) is in contact with the bottom of the cover (12).

7. The multi-stage fine filtration device for biological enzyme preparations according to claim 1, characterized in that: The locking component (19) includes a rotating seat (191) fixedly connected to the bottom of the outer ring of the base (11). The rotating seat (191) is rotatably connected to a rotating rod (192). The rotating rod (192) is threadedly connected to a threaded sleeve (194). A limiting block (193) is rotatably connected to the threaded sleeve (194). The outer extension of one side of the limiting block (193) contacts the bottom outer ring of the cover (12).

8. The multi-stage fine filtration device for biological enzyme preparations according to claim 1, characterized in that: The pore size of the microporous membrane filter element (15) in the pre-filter (1), coarse filter (2) and fine filter (3) gradually decreases.

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