Sample injection device for cytometric analysis

Abstract

The utility model provides a sample putting device for cell counting analysis, this sample putting device includes: the input shell, the input shell bottom fixed communication has the sample pipe, the sample pipe bottom side with the flow type cavity of flow cytometer intercommunication, automatic push mechanism, automatic push mechanism installs in the side surface of flow cytometer, rotating part, rotating part installs in the side surface of flow cytometer, rotating part with automatic push mechanism bottom side connection, fixed assembly, fixed assembly installs in the side surface of rotating part, fixed assembly in the installation has sample test tube. Realize the rotation adjustment of rotating part, and rotating part further synchronous drive fixed assembly rotates, and the synchronous drive sample pipe rotation of fixed assembly is convenient, realizes the angle of automatic rotation sample pipe, and it is convenient to better rotation sample pipe stable pour sample into the input shell, improves the uniformity of putting sample, effectively improves the putting effect, guarantees the stable input of sample.

Description

Technical Field

[0001] This utility model relates to the field of sample delivery technology, and is a sample delivery device for cell counting analysis. Background Technology

[0002] Cell counting and analysis instruments employ advanced image recognition technology and flow cytometry principles to quickly and accurately count, classify, and analyze cell activity. Cell counting and analysis instruments are key analytical tools in modern biology, medicine, and pharmacy. By integrating optical, electronic, and image processing technologies, they achieve automated analysis of cell number, viability, morphology, and surface markers.

[0003] Furthermore, in the current sample delivery process, the worker holds the test tube and pours the sample along the delivery shell. During the delivery process, the worker needs to slowly inject the sample. Manual operation is prone to errors and cannot better control the stable injection of the sample. It may also create negative pressure and draw in air, affecting subsequent use. Utility Model Content

[0004] This invention addresses the technical problems of existing sample delivery processes, where workers hold test tubes and pour them along the delivery shell, requiring slow and deliberate sample injection. Manual operation is prone to errors, making it difficult to control the stable injection of samples and potentially creating negative pressure that draws in air, affecting subsequent use. Therefore, this invention provides a sample delivery device for cell counting analysis.

[0005] This utility model solves the above-mentioned technical problems through the following technical solutions: This invention provides a sample delivery device for cell counting analysis, disposed on one side of a flow cytometer, comprising: An input shell is provided, with a sample tube fixedly connected to the bottom end of the input shell, and the bottom end of the sample tube is connected to the flow cytometry chamber of the flow cytometer. An automatic propulsion mechanism is mounted on the side surface of the flow cytometer; A rotating component is mounted on the side surface of the flow cytometer and connected to the bottom side of an automatic push mechanism; A fixing component is mounted on the side surface of the rotating component, and a sample tube is installed inside the fixing component.

[0006] Furthermore, a connecting rope is fixedly connected to the left side of the top of the insertion shell, and a sealing cap is fixedly connected to the end of the connecting rope. The sealing cap is used to seal the top of the insertion shell.

[0007] Furthermore, the automatic pushing mechanism includes a hydraulic cylinder, a push plate, a guide seat, and a plate-shaped rack. The hydraulic cylinder is fixedly installed on the right side surface of the flow cytometer. The push plate is fixedly connected to the output end of the hydraulic cylinder. The guide seat is fixedly connected to the bottom side of the push plate. A guide column is slidably connected to the side surface of the guide seat. The plate-shaped rack is fixedly connected to the bottom side of the guide seat.

[0008] Furthermore, a guide slider is fixedly connected to the right end of the guide column, and the guide slider is slidably connected to the inner cavity of the guide seat. A fixing seat is fixedly connected to the other end of the guide column, and the fixing seat is fixedly connected to the flow cytometer.

[0009] Furthermore, the rotating component includes an annular rack, a rotating plate, a limiting shaft, and an arc-shaped groove. The left side of the rotating plate is rotatably connected to the limiting shaft, the annular rack is sleeved on the surface of the rotating plate, and an arc-shaped groove is formed on the side surface of the rotating plate.

[0010] Furthermore, the side of the annular rack has a circular structure, and the top side of the annular rack meshes with the plate-shaped rack.

[0011] Furthermore, the limiting shaft has a T-shaped cross-section, and the left end of the limiting shaft is fixedly connected to the right side of the flow cytometer.

[0012] Furthermore, the arc-shaped groove is formed on the surface of the annular rack, and a positioning shaft is slidably connected to the inner cavity on the top side of the arc-shaped groove. The positioning shaft is fixedly connected to the flow cytometer.

[0013] Furthermore, the fixing assembly includes a fixing ring, an adjusting bolt, and a clamping plate. The fixing ring is fixedly connected to the side surface of the annular rack via a fixing post. The adjusting bolt is threaded through the rear surface of the fixing ring, and the end of the adjusting bolt is rotatably connected to the clamping plate.

[0014] Furthermore, the clamp has a circular arc-shaped cross-section when viewed from above, the inner wall of the clamp is in contact with the side surface of the sample tube, and a guide rod is fixedly connected to the other side of the clamp, with the end of the guide rod penetrating the side surface of the fixing ring.

[0015] Based on common knowledge in the field, the above-mentioned preferred conditions can be combined arbitrarily to obtain various preferred embodiments of this utility model.

[0016] The positive and progressive effects of this utility model are as follows: The sample delivery device for cell counting analysis proposed above uses a fixing component to clamp and fix the sample tube, ensuring stable placement and facilitating sample delivery. Simultaneously, an automatic pushing mechanism is activated, which drives a rotating component to rotate. This rotation adjusts the component, which in turn synchronously rotates the fixing component, allowing the fixing component to synchronously rotate the sample tube. This automatic rotation of the sample tube angle facilitates better rotation and stable sample pouring into the delivery shell, improving sample uniformity and preventing over-pouring that could create negative pressure. This effectively enhances delivery efficiency and ensures stable sample delivery. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application.

[0018] Figure 1 This is a three-dimensional structural diagram of the sample delivery device of this utility model.

[0019] Figure 2 This utility model is a sample dispensing device. Figure 2 A magnified schematic diagram of the structure at point A in the middle.

[0020] Figure 3 This is a side sectional view of the connection structure between the guide column and the guide seat of the sample delivery device of this utility model.

[0021] Figure 4 This is a cross-sectional view of the connection structure between the rotating plate and the limiting shaft of the sample delivery device of this utility model.

[0022] Explanation of reference numerals in the attached figures 1. Flow cytometer; 2. Sample tube; 3. Drop-in shell; 4. Sealing cap; 5. Automatic push mechanism; 51. Hydraulic cylinder; 52. Push plate; 53. Guide seat; 54. Plate rack; 55. Fixing seat; 56. Guide column; 57. Guide slider; 6. Rotating component; 61. Ring rack; 62. Limiting shaft; 63. Arc groove; 64. Positioning shaft; 65. Rotating plate; 7. Fixing assembly; 71. Fixing ring; 72. Adjusting bolt; 73. Clamping plate; 74. Guide rod; 75. Fixing column; 8. Sample tube. Detailed Implementation

[0023] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0024] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate for the embodiments of this application described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0025] In this application, the terms "upper," "lower," "left," "right," "front," "rear," "top," "bottom," "inner," "outer," "middle," "vertical," "horizontal," "lateral," and "longitudinal" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. These terms are primarily for the purpose of better describing this application and its embodiments, and are not intended to limit the indicated device, element, or component to having a specific orientation, or to be constructed and operated in a specific orientation.

[0026] Furthermore, in addition to indicating location or positional relationship, some of the aforementioned terms may also have other meanings. For example, the term "above" may also be used in some cases to indicate a certain dependency or connection relationship. Those skilled in the art can understand the specific meaning of these terms in this application based on the specific circumstances.

[0027] Furthermore, the terms "installation," "setup," "equipped with," "connection," "linking," and "socketing" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral structure; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium, or an internal connection between two devices, components, or parts. Those skilled in the art can understand the specific meaning of these terms in this application based on the specific circumstances.

[0028] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other.

[0029] like Figure 1-4 As shown, the sample delivery device for cell counting analysis includes: An input shell 3 is provided, and a sample tube 2 is fixedly connected to the bottom end of the input shell 3. The bottom end of the sample tube 2 is connected to the flow cytometer chamber of the flow cytometer 1. Automatic pushing mechanism 5, which is mounted on the side surface of flow cytometer 1; Rotating component 6 is mounted on the side surface of flow cytometer 1 and is connected to the bottom side of automatic push mechanism 5; A fixing component 7 is installed on the side surface of the rotating component 6, and a sample tube 8 is installed inside the fixing component 7.

[0030] The sample tube 2, which stores the sample, is placed in the fixing component 7. The fixing component 7 clamps and fixes the sample tube 2, ensuring its stable placement and facilitating sample delivery. Simultaneously, by activating the automatic pushing mechanism 5, the automatic pushing mechanism 5 drives the rotating component 6 to rotate, thereby adjusting the rotation of the rotating component 6. The rotating component 6 then synchronously drives the fixing component 7 to rotate, allowing the fixing component 7 to synchronously drive the sample tube 2 to rotate. This achieves automatic rotation of the sample tube 2, making it easier to rotate the sample tube 2 and stably pour the sample into the delivery shell, improving the uniformity of sample delivery, avoiding excessive pouring and negative pressure, effectively improving the delivery effect, and ensuring stable sample delivery.

[0031] A connecting rope is fixedly connected to the top left side of the insertion shell 3, and a sealing cap 4 is fixedly connected to the end of the connecting rope. The sealing cap 4 is used to seal the top of the insertion shell 3.

[0032] The automatic pushing mechanism 5 includes a hydraulic cylinder 51, a pushing plate 52, a guide seat 53, and a plate-shaped rack 54. The hydraulic cylinder 51 is fixedly installed on the right side surface of the flow cytometer 1. The pushing plate 52 is fixedly connected to the output end of the hydraulic cylinder 51. The guide seat 53 is fixedly connected to the bottom side of the pushing plate 52. A guide post 56 is slidably connected to the side surface of the guide seat 53. The plate-shaped rack 54 is fixedly connected to the bottom side of the guide seat 53.

[0033] The hydraulic cylinder 51 pushes the fixedly connected push plate 52 to move, the push plate 52 drives the fixedly connected guide seat 53 to move, the guide seat 53 moves along the guide column 56, so that the guide seat 53 can move stably in the horizontal direction and ensure the stability of the guide seat 53. The guide seat 53 drives the plate-shaped rack 54 to move, so that the plate-shaped rack 54 can drive the rotating part 6 to rotate, which facilitates the rotation and tilting of the sample tube 2.

[0034] The guide column 56 is fixedly connected to the right end of the guide slider 57, which is slidably connected to the inner cavity of the guide seat 53. The other end of the guide column 56 is fixedly connected to the fixing seat 55, which is fixedly connected to the flow cytometer 1.

[0035] The rotating component 6 includes an annular rack 61, a rotating plate 65, a limiting rotating shaft 62, and an arc-shaped groove 63. The left side of the rotating plate 65 is rotatably connected to the limiting rotating shaft 62. The annular rack 61 is sleeved on the surface of the rotating plate 65, and an arc-shaped groove 63 is formed on the side surface of the rotating plate 65.

[0036] The annular groove on the surface of the rotating plate 65 rotates along the positioning shaft 64, which facilitates the stable rotation of the rotating plate 65. The limiting shaft 62 effectively ensures that the rotating plate 65 rotates coaxially along the limiting shaft 62, thus ensuring the stable rotation of the rotating plate 65.

[0037] The annular rack 61 has a circular annular structure on its side, and the top side of the annular rack 61 is engaged with the plate-shaped rack 54.

[0038] The limiting shaft 62 has a T-shaped cross-section, and the left end of the limiting shaft 62 is fixedly connected to the right side of the flow cytometer 1.

[0039] The arc-shaped groove 63 is formed on the surface of the annular rack 61, and a positioning shaft 64 is slidably connected to the inner cavity of the top side of the arc-shaped groove 63. The positioning shaft 64 is fixedly connected to the flow cytometer 1.

[0040] The fixing component 7 includes a fixing ring 71, an adjusting bolt 72, and a clamping plate 73. The fixing ring 71 is fixedly connected to the side surface of the annular rack 61 via a fixing post 75. The adjusting bolt 72 is threaded through the rear surface of the fixing ring 71, and the end of the adjusting bolt 72 is rotatably connected to the clamping plate 73.

[0041] The sample tube 2 is placed inside the fixing ring 71. The adjusting bolt 72 is rotated, and the adjusting bolt 72 pushes the rotating clamp 73 to move. The clamp 73 moves stably under the guidance of the guide post 56. Under the adjustment of the adjusting bolt 72, the adjusting bolt 72 pushes the clamp 73 to stably clamp the sample tube 2, effectively improving the fixation stability of the sample tube 2.

[0042] The clamping plate 73 has a circular arc-shaped cross-section when viewed from above. The inner wall of the clamping plate 73 is in contact with the side surface of the sample tube 8. A guide rod 74 is fixedly connected to the other side of the clamping plate 73, and the end of the guide rod 74 passes through the side surface of the fixing ring 71.

[0043] The circuits, electronic components, and modules involved are all existing technologies, which can be fully implemented by those skilled in the art, and need not be elaborated upon. The content protected by this application does not involve any improvement to the software and methods.

[0044] This utility model is not limited to the above-described embodiments. Any changes in its shape or structure fall within the protection scope of this utility model. The protection scope of this utility model is defined by the appended claims. Those skilled in the art can make various changes or modifications to these embodiments without departing from the principles and essence of this utility model, but all such changes and modifications fall within the protection scope of this utility model.

Claims

1. A sample delivery device for cell counting analysis, disposed on one side of a flow cytometer (1), characterized in that, include: An input shell (3) is provided, and a sample tube (2) is fixedly connected to the bottom end of the input shell (3). The bottom end of the sample tube (2) is connected to the flow cytometer (1). An automatic pushing mechanism (5) is installed on the side surface of the flow cytometer (1); Rotating component (6), the rotating component (6) is mounted on the side surface of the flow cytometer (1), and the rotating component (6) is connected to the bottom side of the automatic push mechanism (5); A fixing component (7) is installed on the side surface of the rotating part (6), and a sample tube (8) is installed inside the fixing component (7).

2. The sample delivery device for cell counting analysis as described in claim 1, characterized in that: A connecting rope is fixedly connected to the left side of the top of the input shell (3), and a sealing cap (4) is fixedly connected to the end of the connecting rope. The sealing cap (4) is used to seal the top of the input shell (3).

3. The sample delivery device for cell counting analysis as described in claim 1, characterized in that: The automatic pushing mechanism (5) includes a hydraulic cylinder (51), a pushing plate (52), a guide seat (53), and a plate rack (54). The hydraulic cylinder (51) is fixedly installed on the right side surface of the flow cytometer (1). The output end of the hydraulic cylinder (51) is fixedly connected to the pushing plate (52). The bottom side of the pushing plate (52) is fixedly connected to the guide seat (53). The side surface of the guide seat (53) is slidably connected to the guide column (56). The bottom side of the guide seat (53) is fixedly connected to the plate rack (54).

4. The sample delivery device for cell counting analysis as described in claim 3, characterized in that: The guide column (56) is fixedly connected to a guide slider (57) at the right end. The guide slider (57) is slidably connected to the inner cavity of the guide seat (53). The guide column (56) is fixedly connected to a fixing seat (55) at the other end. The fixing seat (55) is fixedly connected to the flow cytometer (1).

5. The sample delivery device for cell counting analysis as described in claim 1, characterized in that: The rotating component (6) includes an annular rack (61), a rotating plate (65), a limiting rotating shaft (62), and an arc groove (63). The left side of the rotating plate (65) is rotatably connected to the limiting rotating shaft (62). The annular rack (61) is sleeved on the surface of the rotating plate (65), and an arc groove (63) is opened on the side surface of the rotating plate (65).

6. The sample delivery device for cell counting analysis as described in claim 5, characterized in that: The annular rack (61) has a circular annular structure on its side, and the top side of the annular rack (61) is engaged with the plate-shaped rack (54).

7. The sample delivery device for cell counting analysis as described in claim 5, characterized in that: The limiting shaft (62) has a T-shaped cross-section, and the left end of the limiting shaft (62) is fixedly connected to the right side of the flow cytometer (1).

8. The sample delivery device for cell counting analysis as described in claim 5, characterized in that: The arc-shaped groove (63) is formed on the surface of the annular rack (61), and a positioning shaft (64) is slidably connected to the inner cavity of the top side of the arc-shaped groove (63). The positioning shaft (64) is fixedly connected to the flow cytometer (1).

9. The sample delivery device for cell counting analysis as described in claim 1, characterized in that: The fixing component (7) includes a fixing ring (71), an adjusting bolt (72), and a clamping plate (73). The fixing ring (71) is fixedly connected to the side surface of the annular rack (61) via a fixing post (75). The adjusting bolt (72) is threaded through the rear surface of the fixing ring (71). The end of the adjusting bolt (72) is rotatably connected to the clamping plate (73).

10. The sample delivery device for cell counting analysis as described in claim 9, characterized in that: The clamp (73) has a circular arc structure when viewed from above. The inner wall of the clamp (73) is in contact with the side surface of the sample tube (8). A guide rod (74) is fixedly connected to the other side of the clamp (73). The end of the guide rod (74) passes through the side surface of the fixing ring (71).

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