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2 results about "Aspartyl Proteinases" patented technology

Aspartyl proteases are one of the eukaryotic protease enzymes that catalyze peptide substrates using aspartate residue. It is usually in an acidic pH range which is inhibited by pepstatin.

Methods of characterizing and purifying VEGF receptor fusion protein

UndeterminedAE202602120AVEGF receptorsCathepsin
Anti-VEGF proteins including the VEGF trap protein aflibercept can be produced to have a low level of an aspartyl protease (e.g., a low level of cathepsin D), such as less than 1 ppm of the aspartyl protease.
Owner:REGENERON PHARMACEUTICALS INC

Recombinant milk polypeptide compositions free of aspartyl protease activity

PendingUS20260152753A1Microorganism/unicellular-algae proteins working-upNucleic acid vectorOrganic chemistryProtease
The present invention relates to food products comprising recombinant polypeptide compositions that are substantially free of aspartyl protease-like activity. The invention also relates to compositions comprising recombinant milk polypeptides and that are substantially free of aspartyl protease-like activity; and methods and tools for manufacture of such compositions.
Owner:DSM IP ASSETS BV