Patents
Literature
1 results about "Flagellum motility" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Flagellar motility, a swimming-like motion (observed for example in spermatozoa, propelled by the regular beat of their flagellum, or E. coli, which swims by rotating a helical prokaryotic flagellum) amoeboid movement, a crawling-like movement, which also makes swimming possible. gliding motility. swarming motility.
Pseudomonas aeruginosa flagella inhibiting peptide and synthesis method and application thereof
The application discloses a flagellum inhibiting peptide of pseudomonas aeruginosa and a preparation method and application thereof, and the sequence of the flagellum inhibiting peptide is Lys-Ile-Gly-Leu-Phe-Arg-Trp-Arg. The synthetic inhibiting peptide has a time-dependent self-assembly ability, can gradually evolve from scattered granular into filamentous structure, and finally forms a stable net-like morphology. The synthetic inhibiting peptide can significantly inhibit the flagellum motility of PAO1 and other strains of pseudomonas aeruginosa, and has synergistic antibacterial activity when combined with allicin, ciprofloxacin, meropenem, levofloxacin, polymyxin B and the like. Moreover, the synthetic inhibiting peptide has obvious bacteriostatic and healing-promoting effects on burn wound infection.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE