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74results about How to "Active ingredient reduction" patented technology

Preparation method of defoaming agent for waterborne system

The invention relates to a preparation method of a defoaming agent for a waterborne system. The preparation method of the defoaming agent for the waterborne system comprises the following steps: a) adding silicon oil, gaseous silicon dioxide and catalyst into a reaction container according to proportions, and preparing silicon cream under an agitating condition protected by nitrogen; b) adding hydrogen-containing silicon oil and allyl polyether into the reaction container, agitating under the protection of nitrogen, increasing temperature and adding an initiator for reaction to obtain polyether modified organic silicon; c) jading the silicon cream obtained in step a), the polyether modified organic silicon obtained in step b) and an emulsifier into the reaction container, adding water for emulsification under a high-speed agitating condition, and adding a thickening agent to regulate viscosity to obtain a product. The defoaming agent prepared by adopting the preparation method provided by the invention has the advantages that the active components are low, the manufacturing cost is low and the environmental friendliness is better; the emulsification is stable, the compatibility in the waterborne system is good, the defoaming agent is easy to disperse, the surface tension is low, the defoaming speed is quick, the foam inhibiting time is long, the thermal resistance, shear resistance and acid and alkali resistance thereof are good, and the defoaming agent can adapt to various places; the defoaming agent can be separately used and can also be jointly used with other adjuvants, the stability is good, the phenomenon of oil floating due to demulsification does not occur, no sediment is produced and shrinkage cavities during coating are not caused; and the defoaming agent is also very effective to non-waterborne systems.
Owner:KITO CHEM CO LTD

Supercritical CO2 variable-temperature variable-pressure extraction method of lucid ganoderma spore oil

The invention relates to a supercritical CO2 variable-temperature variable-pressure extraction method of lucid ganoderma spore oil. The method comprises the steps that: 1, lucid ganoderma spores are subjected to wall breaking, such that lucid ganoderma spore powder is obtained; 2, the wall-broken lucid ganoderma spore powder is prepared into particles with a dry-pressing method, such that particles with a size of 20-60 meshes are obtained; 3, the spore powder particles are placed into a supercritical CO2 extraction kettle with a three-stage separation structure; an ethanol water solution with a mass percentage of 20-95% is adopted as carrying agent, wherein 20-300ml of the 20-95% ethanol water solution is placed with each kilogram of material in the extraction kettle; and supercritical extraction is carried out, wherein an extraction pressure is 20-50MPa. The extraction process is a multi-stage extraction process, wherein extraction is carried out for 1-4h under a temperature of 30-40 DEG C, and extraction is carried out for 1-4h under a temperature of 40-60 DEG C. With the method, various effective components in lucid ganoderma spores can be more effectively extracted, such that the possibility for the lucid ganoderma spore active components to be broken is effectively reduced. The quality of the extraction product is improved, and the requirement of people is satisfied.
Owner:浙江龙泉佳宝生物科技有限公司

Production method of fruit seed traditional Chinese medicines

The invention discloses a production method of fruit seed traditional Chinese medicines. Nutrients are applied in the growth process of the traditional Chinese medicines, and are mainly composed of 30-70wt% of nucleotide salt and deoxynucleotide salt, and 30-70wt% of trace elements, and do not include glucose or/and amino acids. An application method of the nutrients is characterized in that the nutrients are dissolved in water to obtain a solution, and the solution is sprayed. The production method has the advantages of simplicity, product and quality improvement, resistance and uniformity enhancement, reduction of the content of harmful substances, cost saving, yield increase and synergistic effect. Harvested fruit seed traditional Chinese medicines having a uniform size account for 80-90% of the total amount of the harvested fruit seed traditional Chinese medicines, the output of the production method is 20-40% higher than the output of traditional production methods, and the content of main components in the fruit seed traditional Chinese medicines obtained in the invention is 20-50% higher than the content of main components in the fruit seed traditional Chinese medicines produced through the traditional methods. The harvested fruit seed traditional Chinese medicines can be processed to prepare high-quality decoction pieces, and the extraction yield of effective components from the fruit seed traditional Chinese medicines obtained in the invention is 15-49% higher than the extraction yield of effective components from the fruit seed traditional Chinese medicines produced through the traditional methods. The production method in the invention has same, even better effects than a production method with the patent number of 201010514241.X and the publication number of CN102180721B.
Owner:安徽省永香中药饮片有限公司

Production method of rhizomatic traditional Chinese medicinal material

The invention discloses a production method of a rhizomatic traditional Chinese medicinal material. The method comprises the step that a nutrient is applied in a growth process of the rhizomatic traditional Chinese medicinal material, wherein the nutrient mainly comprises the following ingredients by weight percentage: 30-70% of nucleotide salt and 30-70% of medium trace element, and does not comprise glucose or/and amino acid. An application method of the nutrient comprises the steps of dissolving with water and then spraying. The nutrient further comprises a filler which is one or more out of starch, dextrin, cellulose, povidone, magnesium stearate, calcium sulfate and magnesium sulfate. The harvested traditional Chinese medicinal material is uniform in size; a yield of the traditional Chinese medicinal material is 20-80% higher than that produced by the traditional method; the content of the main ingredients is 10-50% higher than that produced by the traditional method; and a yield of preparing the harvested traditional Chinese medicinal material into a high-quality herbal piece for decoction or extracting the active ingredients is 15-49% higher than that produced by the traditional method. Although active ingredients in a composition are reduced, the effect of the nutrient can still reach and even exceed that of an invention patent with the publication number of CN102079671B and the patent number of 201010514219.5, and the nutrient is economical, environment-friendly and strong in pertinence, increases the yield and income, improves an effect and resistance and has a good effect of improving quality.
Owner:安徽普仁中药饮片有限公司

Chinese traditional medicine preparation for treating coughs and preparation method of same

The invention discloses a Chinese traditional medicine preparation for treating coughs. The Chinese traditional medicine preparation is prepared from the seven kinds of Chinese traditional medicine of coastal glehnia root, radix ophiopogonis, rhizoma polygonati odorati, radix trichosanthis, folium mori, semen lablab album, radix glycyrrhizae. A preparation method of the Chinese traditional medicine preparation comprises the following steps: the seven kinds of Chinese traditional medicine are added with water and decocted in the water, or is subjected to heating reflux through an aqueous solution containing alcohol, so as to extract liquid extract; the liquid extract is collected, filtered and subjected to vacuum concentration; the concentrated liquid extract is treated with a macroporous absorbent resin column and eluted with water or an aqueous solution containing alcohol; the eluent is collected and concentrated; auxiliary materials are added to the concentrated eluent, so as to make the concentrated eluent into a dosage form suitable for clinical medication. According to the preparation method of the Chinese traditional medicine preparation, the active components of adenophora and radix ophiopogonis soup are concentrated, and the inactive components of the adenophora and radix ophiopogonis soup are reduced; the improvement on the curative effect of the Chinese traditional medicine preparation is facilitated; side effects and dose of the Chinese traditional medicine preparation are reduced; the medicine taking compliance of patients is improved. The invention further provides a novel Chinese patent drug for treating lung yin deficiency-type dry coughs. The Chinese traditional medicine preparation and the preparation method thereof are of great significance for meeting the demand of clinical medication.
Owner:HUBEI LIYI PHARM TECH CO LTD

Nutrient for growing traditional Chinese medicine flowers and use method thereof

The invention discloses a nutrient for growing traditional Chinese medicine flowers and a use method thereof, and belongs to the field of fertilizers or plant growth regulators. The traditional Chinese medicine flowers include honeysuckles, China roses and inula flowers. The nutrient is prepared from 1 g of potassium nucleotide and potassium deoxynucleotide and 9 g of corn starch; or 98 g of the nutrients are prepared in the mode that 90 g of market ribonucleic acid and 10 g of desoxyribonucleic acid are mixed and dissolved into a KOH solution, and stirring, filtering, neutralizing, pressure reducing, concentrating, crystallizing, drying and the like are carried out. Nucleotide salt is sylvite of four kinds of 5'-mixed nucleotide, and deoxynucleotide salt is sylvite of five kinds of 5'-mixed deoxynucleotide. The use method includes the step of carrying out spraying twice, wherein the first time of spraying is carried out in the flower bud period or the bloom beginning period, and 30 g of the nutrient and 30 liters of water are mixed to be sprayed to one mu of land; the second time of spraying is carried out in the full-bloom period, and 30 g of the nutrient and 36 liters of water are mixed to be sprayed to one mu of land. Yield and mass can be increased, quality can be improved, resistance and evenness can be improved, the content of harmful substances can be reduced, cost can be saved, income can be increased, efficiency can be improved, and the method is easy and convenient.
Owner:安徽天之正生物科技有限公司

Preparation method of nutrient for promoting growth of flower-type traditional Chinese medicinal materials

InactiveCN103626544ASave raw materials and costReasonable ratioFertilizer mixturesNutrientCytidine monophosphate
The invention discloses a preparation method of a nutrient for promoting the growth of flower-type traditional Chinese medicinal materials. The nutrient comprises 30-70 percentage by weight of nucleotide salts, 30-70 percentage by weight of medium and trace elements, starch serving as a filling agent and the like and does not comprise glucose or/and amino acid, wherein the nucleotide salts refer to potassium or sodium salts of four types of 5'-mixed nucleotides comprising 5'-adenylate dipotassium or sodium, 5'-guanylic acid dipotassium or sodium, 5'-cytidine monophosphate dipotassium or sodium and 5'-uridylic acid dipotassium or sodium which are obtained after alkaline hydrolysis of ribonucleic acids, and the medium and trace elements refer to Mn, B and Fe, and specifically relate to manganese sulfate, borax and ferrous sulfate. The preparation method of the nutrient comprises the following steps: mixing the nucleotide salts and the medium and trace elements, crushing, and sieving by using a 50-200 mesh sieve. The effect of the nutrient can reach even exceed the effect of the invention patent with the notification number of CN102079666B, ZL201010514231.6. The preparation method is economical and simple.
Owner:安徽亳州浙皖中药饮片股份有限公司

Method for screening active ingredient groups in different processed products of curcuma wenyujin by bivariate correlation analysis method

InactiveCN111679045AStrong correlationNo significant correlationTesting medicinal preparationsBiotechnologyEfficacy
Various traditional Chinese medicine components are adopted, and active components related to the medicine effect are found to be recognized difficulties in the field due to the characteristics of thesynergistic effect. The invention provides a method for screening active component groups in different processed products of curcuma wenyujin by using a bivariate correlation analysis method. The method comprises the following steps: measuring the change rule of blood entering components and drug effect indexes of different processed products of curcuma wenyujin along with time, and carrying outbivariate correlation analysis on component change and drug effect index change. The method can be used for obtaining three decoction pieces of rhizoma wenyujin longae, curcuma zedoary and vinegar-processed curcuma zedoary as well as active ingredients related to the efficacy of promoting blood circulation to remove blood stasis; although the curcuma zedoary has more blood-entering components in the three decoction pieces, the correlation with the drug effect is poorer than that of the raw curcuma zedoary and the vinegar curcuma zedoary, and the quantity of the blood-entering components in thevinegar curcuma zedoary is reduced, but the blood-entering components in the vinegar curcuma zedoary show extremely remarkable correlation with the drug effect index. According to the method providedby the invention, the relevance and similarities and differences between the blood-entering components of the three decoction pieces and the blood-activating and stasis-removing drug effects are defined, and a detailed material basis is provided for the research on the effect-taking and processing mechanism of traditional Chinese medicines, clinical practice guidance and the development of traditional Chinese medicine products.
Owner:NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Nutrient for promoting growth of root-stock Chinese herbal medicines

The invention discloses a nutrient for promoting the growth of root-stock Chinese herbal medicines. The nutrient mainly includes the following components in percentage by weight: 30 to 70 percent of nucleotide salt and 30 to 70 percent of medium trace elements. The nutrient components do not include glucose and/or amino acid. The nutrient further includes one or more of the following fillers: starch, dextrin, cellulose, povidone, magnesium stearate, calcium sulfate or magnesium sulfate. Magnesium stearate and magnesium sulfate in the medium trace elements are the same as the magnesium stearate and magnesium sulfate in the fillers. The invention has the advantages of lower production cost, less consumption, simpler processing and longer validity for product preservation; although active ingredients in the compound are reduced, the effects still meet and even surpass the effects of the invention patent with the Notice of Authorization No. CN102079671B and the Patent No. 201010514219.5; the nutrient is economical, environment-friendly (being non-toxic, innocuous, residue-free, and without any adverse side effects) and highly pertinent, can increase production, yields and effects, improves resistance, and is remarkable in quality improvement effect.
Owner:安徽省永香中药饮片有限公司

Fruit seed type medicinal plant growth nutrient preparation method

The invention discloses a production method of fruit seed traditional Chinese medicines. Nutrients are applied in the growth process of the traditional Chinese medicines, and are mainly composed of 30-70wt% of nucleotide salt and deoxynucleotide salt, and 30-70wt% of trace elements, and do not include glucose or / and amino acids. An application method of the nutrients is characterized in that the nutrients are dissolved in water to obtain a solution, and the solution is sprayed. The production method has the advantages of simplicity, product and quality improvement, resistance and uniformity enhancement, reduction of the content of harmful substances, cost saving, yield increase and synergistic effect. Harvested fruit seed traditional Chinese medicines having a uniform size account for 80-90% of the total amount of the harvested fruit seed traditional Chinese medicines, the output of the production method is 20-40% higher than the output of traditional production methods, and the content of main components in the fruit seed traditional Chinese medicines obtained in the invention is 20-50% higher than the content of main components in the fruit seed traditional Chinese medicines produced through the traditional methods. The harvested fruit seed traditional Chinese medicines can be processed to prepare high-quality decoction pieces, and the extraction yield of effective components from the fruit seed traditional Chinese medicines obtained in the invention is 15-49% higher than the extraction yield of effective components from the fruit seed traditional Chinese medicines produced through the traditional methods. The production method in the invention has same, even better effects than a production method with the patent number of 201010514241.X and the publication number of CN102180721B.
Owner:HEFEI KAIGE INFORMATION TECH

Production method for flower traditional Chinese medicine

The invention discloses a production method of a flos traditional Chinese medicine. The production method is characterized in that nutrients are used during the growth of the flos traditional Chinese medicine, wherein the nutrients include the following components in percentage by weight: 30 to 70% of nucleotide salt and 30 to 70% of medium trace element, and exclude glucose or / and amino acids; the nucleotide salt is the sylvite or sodium salt of four 5'-mixed nucleotides and obtained by hydrolyzing ribonucleic acid alkaline, namely, wherein the four 5'-mixed nucleotides are namely 5'-adenylate dipotassium or sodium, 5'-guanylic dipotassium or sodium, 5'-cytidine monophosphate dipotassium or sodium, 5'-uridylic acid dipotassium or sodium; and the medium trace element includes Mn, B and Fe, namely manganese sulfate, borax and ferrous sulfate. The production method of the flos traditional Chinese medicine has the effect reaching and even exceeding the effect of a patent for invention with publication patent number of CN102079666B and patent number of ZL201010514231.6. The method is economic and simple. The obtained flos traditional Chinese medicine is large and uniform in flower, the uniformity is up to 70 to 90%, the output is 20 to 40% higher than that of flos traditional Chinese medicine produced by the traditional method, the main components account for 10 to 25%, the obtained traditional Chinese medicines can be prepared into quality decoction pieces, or active ingredients can be extracted, and the yield is up to 10 to 22%.
Owner:HEFEI KAIGE INFORMATION TECH

Trichosanthes kirilowii maxim and Chinese trichosanthes root production method

The invention discloses a trichosanthes kirilowii maxim and Chinese trichosanthes root production method and belongs to the field of traditional Chinese medicine production. Nutrients are sprayed for three times each year after the year when planting is carried out, wherein a, 2g of nucleotide sylvite and deoxynucleotide sylvite and 2g of microelements are taken; b, 7g of nucleotide sylvite and deoxynucleotide sylvite and 5g of microelements are taken; c, 5g of nucleotide sylvite and deoxynucleotide sylvite and 4g of microelements are taken. The materials are smashed, screened and evenly mixed, wherein the weight ratio of the microelements including Mn, B, Fe, Zn, Cu and Mo is 5:3:3:3:2:1, the nucleotide sylvite includes four kinds of 5'-dipotassium mixed with nucleotide, and the deoxynucleotide sylvite includes five kinds of 5'-dipotassium mixed with deoxynucleotide. When veins grow to 30 cm or so, the nutrient a is mixed with 20 liters of water and sprayed for the first time. In the early flowering stage of plants, the nutrient b is mixed with 30 liters of water and sprayed for the second time. In the full-bloom stage, the nutrient c is mixed with 40 liters of water and sprayed. The yield of trichosanthes kirilowii maxim is increased by 20%-30%, and the yield of Chinese trichosanthes roots is increased by over 30%. Cost is reduced.
Owner:HEFEI KAIGE INFORMATION TECH
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