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41results about How to "Excellent formulation performance" patented technology

Pine pollen and cyclodextrin composition, method for preparing same, use of same in preparation of health-care products for resisting fatigue and improving immunity of organisms

InactiveCN101518552AHigh activitySolve the problem of easy oxidation and deterioration of nutrientsAntinoxious agentsPharmaceutical non-active ingredientsMass ratioAdditive ingredient
The invention disclose a pine pollen and cyclodextrin composition, a method for preparing the same and application of the same in the preparation of health-care products for resisting fatigue and improving immunity of organisms. The composition consists of extract of wall-broken pine pollen and cyclodextrin, and is characterized in that the mass ratio of the pine pollen or the extract of the pine pollen to the cyclodextrin is 1:0.6-5. The preparation method comprises the following steps of: adding pure water and the cyclodextrin into to the wall-broken pine pollen or the extract of the wall-broken pine pollen in an amount which are two times of that of the wall-broken pine pollen or the extract of the wall-broken pine pollen; uniformly stirring the mixture and grinding the mixture for 0.5 to 3 hours; drying the ground mixture under reduced pressure at a temperature below 50 DEG C; and crushing the mixture and passing the crushed mixture through a sieve to obtain the pine pollen and cyclodextrin composition. The application of the pine pollen and cyclodextrin composition in the preparation of the health-care products for resisting the fatigue and improving the immunity of the organisms has the advantages that: the composition is strong in stability; the preparations have good performance; the stability of active ingredients is obviously improved compared with the wall-broken pine pollen on the market; the products are long in storage time and convenient in transport; and the active ingredients of pine pollen can be absorbed by human bodies.
Owner:NANJING NORMAL UNIVERSITY +1

Biphasix cannabinoid delivery

InactiveUS20180360757A1Easy repeat useEffectively releaseHydroxy compound active ingredientsAntipyreticOil in waterCannabinoid
A biphasix multilayered lipid vesicle cannabinoid composition comprising: (a) a first phase comprising a first oil-in-water emulsion; and (b) a second phase suspended in the first phase, the second phase comprising multilamellar lipid vesicles, the multilamellar lipid vesicles entrapping a second oil-in-water emulsion, wherein at least one of the first and second oil-in-water emulsions comprises a therapeutically effective amount of a cannabinoid. The composition for transdermal and topical administration for the treatment of pain.
Owner:ALTUM PHARMA INC

De icing formulation utilizing co-products from lignocellulose to bio fuel process

The use of a side stream and residue from the lignocellulose to ethanol process for use in preventing the formation of ice and in melting ice and snow on roadways. The future lignocellulose to ethanol industry will provide a significant proportion of these streams that provide an organic solution that when added to chloride salts of calcium, magnesium and sodium provides an improved environmentally friendly road deicing product with reduced corrosiveness and increased friction. A deicer composition of calcium chloride aqueous solution containing 25-38% by weight calcium chloride mixed up to 50% by volume of hemicellulose hydrolysis side stream can reduce the corrosivity of calcium chloride to 70% less that of a sodium chloride solution.
Owner:GREENFIELD SPECIALTY ALCOHOLS

Method of producing enteric soft capsule

The present invention addresses the problem of providing a method of producing soft capsules that are enteric and exhibit superior production characteristics. In this method, enteric soft capsules are produced by means of steps (a) and (b), which are: (a) a step for preparing an enteric capsule coating solution which contains gelatin and a low methoxyl pectin having a degree of amidation of 5-25%; and (b) a step for using the prepared enteric capsule coating solution prepared in (a) to encapsulate capsule contents by means of a punching technique. It is preferable for the gelatin to have a jelly strength of 160-330 Bloom, for the degree of esterification of the low methoxyl pectin to be 20-40%, and for the enteric capsule coating solution to contain 30-35 parts by mass of the low methoxyl pectin per 100 parts by mass of the gelatin.
Owner:FUJI CAPSULE

Method for preparing colored ethylene-propylene rubber

ActiveCN102382376AImprove vulcanization reactivityFast vulcanizationRubber materialPolymer science
The invention relates to a method for preparing rubber, especially relates to a method for preparing a colored ethylene-propylene rubber. The invention is characterized in the pigment and rubber are pretreated and mixed, a partial high activity ultra fast accelerator is used, a partial activator is added, so that a sulfuration activity of the rubber material can be improved for further, thereby the sulfuration speed of the rubber material can be greatly increased, and the sulfuration time can be decreased, simultaneously, the formula performance is higher than that of the original formula; the product has the advantages of excellent appearance, middle and high hardness, high compression resistance and permanent deformation resistance, high tensile strength and maximum elongation, excellent aging resistance and anti-ozone performance, and can keep the excellent performance and appearance under the rigorous usage environment, the method of the invention has the advantages of reasonable raw material ratio and simple process.
Owner:南通威福塑业科技有限公司

Compound microbial agent composition capable of reducing continuous cropping obstacles for crops

The invention belongs to the field of agricultural technologies, and particularly relates to a compound microbial agent composition capable of reducing continuous cropping obstacles for crops. The compound microbial agent composition capable of reducing the continuous cropping obstacles for the crops comprises microbial agents and synergistic compositions. The microbial agents comprise paenibacillus polymyxa, bacillus amyloliquefaciens and streptomyces lavendulae; the synergistic compositions comprise soy isoflavone and polyglutamic acid; a weight ratio of the compound microbial agents to the synergistic compositions is 10:0.2-0.5. The compound microbial agent composition has the advantages that action effects of various components of the compound microbial agent composition supplement one another and are promoted by one another; the compound microbial agent composition is comprehensive in action, excellent antibacterial and disease-resistant effects can be realized after the compound microbial agent composition is used, and soil-borne diseases can be reduced; growth can be promoted, the yield can be increased, and the quality can be improved; effects of improving soil, increasing the fertilizer utilization rate, reducing the fertilizer rate and the like can be realized; the compound microbial agent composition is easy to produce and use; the compound microbial agent composition is environmentally friendly.
Owner:王永强

Insecticidal composition of dinotefuran and bifenthrin and application thereof

The invention discloses an insecticidal composition of dinotefuran and bifenthrin and the application thereof. The active components of the medicine are dinotefuran and bifenthrin, and the mass ratio of dinotefuran and bifenthrin is 1-20:1. Dinotefuran and bifenthrin, that pharmaceutical active components of the insecticidal composition of the present invention, belong to two insecticides with different action mechanism, the mixture of the two insecticides does not conflict with each other, the insecticidal spectrum is expanded, the quick-acting property and the persistent property are improved, and the insecticidal efficiency is improved.
Owner:QINGDAO RAINBOW CHEM CO LTD

Isaria fumosorosea water dispersible granule and preparation method thereof

The invention discloses an Isaria fumosorosea water dispersible granule. The water dispersible granule is prepared from Isaria fumosorosea spore powder, sodium lignosulfonate (CMN), sodium dinaphthylmethanedisulfonate (NNO), isooctyl alcohol polyoxyethylene ether polyoxypropylene ether (CA-60), sodium alpha-olefin sulfonate, corn starch, fumed silica, ammonium sulfate, polyvinylpyrrolidone K30, pre-gelatinized starch, a combination of fumed silica and acid yellow 25 or chrysophenine 12, skim milk powder or chitosan oligosaccharide, water-absorbent resin SAP and diatomaceous earth. Low-cost andhigh-stress resistance fermentation, drying and coarse spore powder preparation processes are adopted; a surfactant with best biocompatibility, wettability, dispersibility, disintegration property and adhesion property is screened; and the invasion and germination ability of the above preparation in low-humidity fields is improved. The production cost is reduced, the performances of the preparation are effectively improved, the shelf life is especially prolonged, and the field drug effect is especially improved.
Owner:SHANXI AGRI UNIV

0.3% matrine compound agent

The invention discloses a 0.3% matrine compounded agent, belonging to plant source biological pesticide, characterized by using a natural plant as a main body, comprising more than five Chinese medicinal plants, prepared by technical extraction of soaking, cooking and filtering and the like. The plant source material and the weight percent are as follow: kuhseng 35-45%, oriental biter weed 10-15%, Chinaberry seed 12-18%, kusnezoff mondshood 10-15%, agrimony 8-13%, nicotiniana rustica 11-16%, also added with radix stemonae stemona 2-5%, triperygium wilfordii 2-5%, the extracts are matched with diluted emulsifying agent, with marked pest prevention effect. The invention is used as a novel highly active biological pesticide, with wide applying foreground.
Owner:JIANGYAN XINGNONG BIO ENG

Bioactive glass hydrocolloid dressing for promoting wound healing

The invention relates to a bioactive glass hydrocolloid dressing for promoting wound healing and a preparation method and application thereof. The hydrocolloid dressing consists of a backing layer, a drug-containing colloid layer and an anti-sticking layer; the drug-containing colloid layer consists of a thermoplastic elastomer, tackifying resin, a plasticizer, an antioxidant, a water-absorbent colloid, acidic particles, bioactive glass and sanggenone G; and the bioactive glass consists of Na2O, CaO, P2O5 and SiO2, and the particle size is 40-60 [mu]m. The drug-containing bioactive glass hydrocolloid dressing of the invention has excellent adhesion performance, drug release performance and high water absorption capacity; the function of promoting wound healing and wound repair of the hydrocolloid dressing can be greatly enhanced; and the dressing is convenient to use, high in stability, low in irritation, and is especially suitable for treating chronic ulcerative wounds such as diabetic ulcers, diabetic feet and bedsores.
Owner:温州医科大学慈溪生物医药研究院

Ultra low volume sulfoxime concentrate

The invention relates to an ultra low volume sulfoxime concentrate. The ultra low volume sulfoxime concentrate is prepared from sulfoxime, an emulsifying agent, a wetting agent, an anti-drifting agent, an evaporation inhibitor and the balance of a solvent. According to the ultra low volume sulfoxime concentrate, all auxiliary agents are organically combined, and a preparation has excellent performance; especially, the compound solvent is selected, so that the volatilization rate is greatly reduced under the condition that excellent dissolubility and low-temperature stability are ensured, and aliquid drop shrinking phenomenon in a liquid drop falling process is effectively reduced.
Owner:上海永阔生物医药科技有限公司

Isaria fumosorosea wettable powder, and preparation method thereof

The invention discloses an isaria fumosorosea wettable powder. The isaria fumosorosea wettable powder is composed of a combination of isaria fumosorosea spore powder, sodium lignosulfonate (CMN), anddispersing agent NNO, a combination of isooctyl alcohol polyoxyethylene ether polyoxypropylene ether (CA-60) and sodium alpha-olefin sulfonate, a combination of polyvinylpyrrolidone-K30, aerosol, andacid yellow 25 or chrysophenine G, skimmed milk powder or chitosan oligosaccharide, super absorbent polymer SAP, and diatomite. The advantages are that: low cost and high resistance fermenting, drying, and spore powder preparation technology is adopted, so that the optimum preparation surfactant is selected based on biocompatibility and wetability, dispersibility and suspensibility tests. The preparation method is capable of improving preparation invasion and germination capability at low humidity conditions, improving the performance of the isaria fumosorosea wettable powder effectively, prolonging preparation self life, and improving preparation field drug effect and effect lasting performance.
Owner:SHANXI AGRI UNIV

Feed for preventing and treating wattle-necked softshell turtle hepatitis disease and a preparation method thereof

The present invention discloses feed for preventing and treating wattle-necked softshell turtle hepatitis disease and a preparation method thereof, and belongs to the chelonia feed processing technology field. The feed consists of the following raw materials: livestock and poultry offals, locusts, silkworm chrysalises, pumpkins, bone meal, table salt, dimethyl-beta-propiothetin, betaine, sodium hydrogen di and Chinese herbal medicine preparations. The feed is prepared by drying, crushing, sieving, mixing, granulating, drying, cooling, packaging and other steps. The feed colligates various Chinese herbal medicine efficacies so that the feed can play roles in protecting liver, resisting bacteria and diminishing inflammation, enhancing organism immunity function, etc. A good absorption effect of the Chinese herbal medicine preparations is observed in wattle-necked softshell turtles, and efficacies of the Chinese herbal medicine preparations last for a long time, so that the feed can enhance disease resistance ability, reduce hepatitis disease mortality, reduce breeding risk of wattle-necked softshell turtles, and can improve economic benefits of farmers. The feed is reasonable in preparation and high in palatability, and can increase feed intake and improve growth rate, shorten growth cycle for the wattle-necked softshell turtles.
Owner:广西高企科技有限公司

Formulation for rapidly vulcanizing ethylene propylene diene monomer and vulcanization method thereof

ActiveCN102140205AImprove vulcanization reactivityFast vulcanizationPolymer scienceVulcanization
The invention relates to a formulation for vulcanizing ethylene propylene diene monomer and a vulcanization method thereof, in particular to a formulation for rapidly vulcanizing ethylene propylene diene monomer and a vulcanization method thereof. The invention aims at providing the formulation for rapidly vulcanizing ethylene propylene diene monomer and the vulcanization method thereof; the method adopts a vulcanization system and multiple accelerating agents and even adopts part of high-activity excessive speed accelerating agent, and part of active agent is added, thereby further improving vulcanizing reactivity of sizing material; vulcanization speed of the sizing material is increased to a larger extent and vulcanization time is reduced; simultaneously, formulation performance is increased than ever; the product produced according to the formulation has the advantages of good appearance, middle and high hardness, high anti-compression permanent deformation, high tensile strength and elongation at rupture, has excellent ageing resistance and ozone resistance performance, can keep good performance and appearance in a harsher using environment; the proportion of the raw materials of the product is reasonable; and the process is simple.
Owner:启东欧常新材料有限公司

Nanometer dispersible oil suspending agent containing profoxydim and quinclorac as well as preparation method and application of nanometer dispersible oil suspending agent

The invention discloses a nanometer dispersible oil suspending agent containing profoxydim and quinclorac and a preparation method and application of the nanometer dispersible oil suspending agent, and relates to the technical field of herbicides. The nanometer dispersible oil suspending agent containing the profoxydim and the quinclorac is prepared from the following components in parts by mass (100 parts in total): 7.5-15 parts of profoxydim, 2.5-5 parts of quinclorac, 0.1-10 part of a nanometer carrier, 1-10 parts of a wetting agent, 1-10 parts of a dispersing agent, 0.1-1 part of a defoaming agent, 7.5-15 parts of a safener, 0.1-1 part of a stabilizer, 1-5 parts of an antifreezing agent, 0.1-5 part of a thickening agent and balance of vegetable oil. According to the invention, the fentrazone-ethyl and the quinclorac are reasonably proportioned, so that the medicinal effect of the herbicide in the paddy field is enhanced, meanwhile, the active ingredients of the pesticide are loadedby the nano-carrier, so that the weeding effect is quick, the lasting period is long, the utilization rate of the pesticide is improved, and the spraying frequency and the dosage are further reduced.
Owner:SHANGHAI XIANGLIN AGRI TECH CO LTD

Chinese herbal medicine preparation for preventing and treating hemorrhagic disease of palea steindachneri and preparation method of Chinese herbal medicine preparation

The invention discloses a Chinese herbal medicine preparation for preventing and treating the hemorrhagic disease of palea steindachneri and a preparation method of the Chinese herbal medicine preparation and belongs to the technical field of processing of additives for testudinate feed. The Chinese herbal medicine preparation comprises raw materials as follows: astragalus membranaceus, goldthread roots, rhubarb, phellodendron bark, galla chinensis, sophora flavescens, largehead atractylodes rhizome, red peony roots, herba portulacae, radix sanguisorbae, mint, hedyotis diffusa, indigowoad leaves, hairyvein agrimonia and folium callicarpae pedunculalae. The Chinese herbal medicine preparation is prepared through steps of sun-drying, smashing, screening, mixing, granulation, drying, cooling, packaging and the like. The Chinese herbal medicine preparation integrates efficacy of multiple Chinese herbal medicines and can have functions of blood cooling, hemostasis, anti-inflammation, flesh engendering, heat clearing, toxicity removing and the like; the palea steindachneri can well absorb the Chinese herbal medicine preparation, the Chinese herbal medicine preparation lasts long, the disease resistance of the palea steindachneri can be enhanced, the probabilities of the hemorrhagic disease of the palea steindachneri can be effectively reduced, the cultivation risk is reduced, and the economic benefits of a farmer are increased.
Owner:广西高企科技有限公司

Easy-to-dissolve blocky CBD crystal form I and preparation method thereof

The invention discloses an easy-to-dissolve blocky CBD crystal form I and a preparation method thereof. The preparation method comprises the following steps: firstly, suspending a CBD crude product ina mixed solvent with the volume ratio of ethanol to water being (1: 1) to (2: 1) to form a suspension with the mass-volume ratio (g / ml) being (1: 20) to (1: 80); heating the obtained suspension, keeping the temperature, and dropwise adding an inorganic alkali liquor into the suspension under a stirring condition for alkalization until the pH value is 9-11 and the suspension is completely dissolved; dropwise adding an inorganic acid aqueous solution for acidification until the pH value is 2-4, stopping heating, standing, and slowly cooling to perform filling crystallization; and finally, sequentially carrying out suction filtration, washing the obtained filter cake, and drying under reduced pressure to obtain the blocky CBD crystal I. The prepared easy-to-dissolve blocky CBD crystal form Iis in a cubic block shape, the purity, namely the content of CBD is larger than 97%, the easy-to-dissolve blocky CBD crystal form I is easy to dissolve in ethyl alcohol, and the diffraction peak intensity of an X-ray powder diffraction pattern of the blocky CBD crystal form I at the position of 2theta being 31.754 is 100%.
Owner:YUNNAN AGRICULTURAL UNIVERSITY

21-deoxymacbecin analogues useful as antitumor agents

The present invention relates to 21-deoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and / or prophylaxis of cancer or B-cell malignancies.
Owner:BIOTICA TECH

Deicing formulation utilizing co-products from lignocellulose to bio fuel process

The use of a side stream and residue from the lignocellulose to ethanol process for use in preventing the formation of ice and in melting ice and snow on roadways. The future lignocellulose to ethanol industry will provide a significant proportion of these streams that provide an organic solution that when added to chloride salts of calcium, magnesium and sodium provides an improved environmentally friendly road deicing product with reduced corrosiveness and increased friction. A deicer composition of calcium chloride aqueous solution containing 25-38% by weight calcium chloride mixed up to 50% by volume of hemicellulose hydrolysis side stream can reduce the corrosivity of calcium chloride to 70% less that of a sodium chloride solution.
Owner:GREENFIELD SPECIALTY ALCOHOLS

Bellidifolin single crystal as well as preparation method and application thereof

The invention relates to bellidifolin single crystal and a preparation method thereof. The bellidifolin single crystal is represented by a single crystal X-ray diffraction spectrum and belongs to a triclinic system, the space group of the bellidifolin single crystal is P-1, the unit cell parameters of the bellidifolin single crystal are as follows: a is equal to 7.0602(14)angstrom, b is equal to 7.5236(15)angstrom, c is equal to 10.662(2)angstrom, alpha is equal to 86.65(3)angstrom, beta is equal to 79.84(3)angstrom and gamma is equal to 84.96(3)angstrom, the unit cell volume V is equal to 554.77(19)angstrom, and the number Z of molecules in a unit cell is 2. The bellidifolin single crystal is yellow transparent crystal at normal temperature and is prepared by dissolving a crude bellidifolin product in an appropriate solvent system by using a recrystallization method, and by further volatilizing a solvent slowly. The bellidifolin single crystal which is prepared by using the preparation method provided by the invention is good in form and high in purity, and the preparation method is simple to operate and good in reproducibility, so that great significance is achieved for further development of the compound.
Owner:TIANJIN AGRICULTURE COLLEGE

Formulation for rapidly vulcanizing ethylene propylene diene monomer and vulcanization method thereof

ActiveCN102140205BImprove vulcanization reactivityFast vulcanizationVulcanizationPolymer science
The invention relates to a formulation for vulcanizing ethylene propylene diene monomer and a vulcanization method thereof, in particular to a formulation for rapidly vulcanizing ethylene propylene diene monomer and a vulcanization method thereof. The invention aims at providing the formulation for rapidly vulcanizing ethylene propylene diene monomer and the vulcanization method thereof; the method adopts a vulcanization system and multiple accelerating agents and even adopts part of high-activity excessive speed accelerating agent, and part of active agent is added, thereby further improvingvulcanizing reactivity of sizing material; vulcanization speed of the sizing material is increased to a larger extent and vulcanization time is reduced; simultaneously, formulation performance is increased than ever; the product produced according to the formulation has the advantages of good appearance, middle and high hardness, high anti-compression permanent deformation, high tensile strength and elongation at rupture, has excellent ageing resistance and ozone resistance performance, can keep good performance and appearance in a harsher using environment; the proportion of the raw materials of the product is reasonable; and the process is simple.
Owner:启东欧常新材料有限公司

Levodropropizine inclusion compound dispersible tablet and preparation method thereof

The invention provides a levodropropizine clathrate dispersible tablet and a preparation method thereof. The invention, which processes levodropropizine as a clathrate firstly and then prepares a dispersible tablet from the levodropropizine clathrate, integrates inclusion and dispersion technologies to take the advantages of the two aspects. The levodropropizine is included by virtue of cyclodextrin and the dispersible tablet is prepared in coordination with accessories of special type and dosage, so as to solve a problem of bitterness and to take an effect of masking bitter taste; and the preparation effect of the dispersible tablet is significantly enhanced and a degradation effect is accelerated. The levodropropizine dispersible tablet prepared according to the formula can be completely released within a short time; the dispersible tablet is reasonable in formula, and is capable of masking the bitter taste, improving the mouthfeel of the levodropropizine dispersible tablet taken by patients and enhancing drug compliance; and the preparation process is simple and easy to implement, strong in operability, stable in process, and is capable of improving the bioavailability and curative effect of the medicine.
Owner:GUIZHOU UNIV
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