2results about How to "Has repair" patented technology

The invention provides an application of recombinant III type humanized collagen in thermal induction of melanogenesis and keratinogenesis cell migration capability reduction, wherein the amino acid sequence of the recombinant III type humanized collagen is as shown in SEQ ID NO.3. The invention also provides an application of the recombinant III type humanized collagen in thermal induction of melanogenesis and keratinogenesis cell migration capability reduction. Test results show that the recombinant III-type humanized collagen can significantly reduce melanogenesis under different heating environment conditions, and the repair effect of cell migration ability decline in the heating environment is improved. According to the invention, the application potential of the recombinant III-type humanized collagen in skin care products is expanded, and the multifunctionality of the recombinant III-type humanized collagen as a novel skin care component is shown. Besides, the skin care product containing the recombinant III-type humanized collagen provided by the invention also has the advantages of safety, effectiveness and no skin irritation or allergy, and the protection effect of the skin care product is remarkably improved.

The present patent application discloses a recombinant human collagen type I and its use. The amino acid sequence of the recombinant human collagen type I is shown in SEQ ID No: 2. The recombinant human collagen type I has good cell proliferation activity, cell migration activity, cell adhesion activity (all better than full-length recombinant human collagen type I or commercially available human collagen), and is easy to produce. The recombinant human collagen type I is expected to have the effects of whitening, moisturizing, soothing and repairing, and can be applied in the fields of cosmetics, external use drugs, skin care products, health care products, tissue engineering materials, medical devices and the like.