Application of anti-intercellular adhesion molecule-1 monoclonal antibody for preparing medicine for treating avian influenza

A technology of adhesion molecules and bird flu, applied in the direction of antibodies, antiviral agents, etc., can solve problems such as no treatment methods
CN101062414BInactive Publication Date: 2011-05-11MILITARY VETERINARY RES INST PLA MILITARY MEDICAL ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
MILITARY VETERINARY RES INST PLA MILITARY MEDICAL ACAD OF SCI
Publication Date
2011-05-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an application with anti-intercellular sticking molecule-1 single antibody to prepare the medicine to treat fowl flu, which is characterized by the following: adopting H5N1 hypotype fowl flu mouse mode of anti-intercellular sticking molecule-1 single antibody of pure; setting the survival rate of treating group higher than matched group of virus; possessing distinctive difference in pathologic change of lung; displaying the miscellaneous index of the treating group higher than the matched group of virus with disease state, body weight of disease state and change of lung index; possessing distinctive treating action for fowl flu mouse without toxic side action for lung. This invention provides criterion for human and mammal fowl flu.
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Description

technical field

[0001] The present invention relates to the application of the antibody, specifically the application of the anti-intercellular adhesion molecule-1 monoclonal antibody as a medicine for treating bird flu. Background technique

[0002] The frequent occurrence of highly pathogenic avian influenza (HPAIV) has seriously affected the development of poultry farming in my country and the world. At present, HPAIV has spread from Asia to Africa and Europe. At the same time, there are increasing reports of avian influenza viruses crossing birds and infecting mammals. The number of AIV-infected people is also increasing, and HPAIV poses a huge threat to human beings. AIV is likely to break through the interspecies barrier and spread among humans, leading to the pandemic or outbreak of human avian influenza. Therefore, preventing and controlling this possible spread is the most important task for the global prevention and control of avian influenza. Highly pathogenic a...

Claims

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