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Receptacle for an aerosolizable pharmaceutical formulation

A technology for pharmaceutical preparations and containers, which is applied in the field of containers for aerosolizable pharmaceutical preparations, can solve the problems of inconsistent drug delivery, inconsistent openings, etc.

Inactive Publication Date: 2010-11-17
NOVARTIS AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effects of incorrect opening may be magnified when the user is unable or unwilling to visually inspect the opening of the capsule
The user may then unknowingly inhale a smaller than desired amount of the pharmaceutical preparation
Additionally, the sharp elements used to create the opening in the capsule can create inconsistent openings in the capsule, which can lead to inconsistent delivery of the aerosolized drug

Method used

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  • Receptacle for an aerosolizable pharmaceutical formulation
  • Receptacle for an aerosolizable pharmaceutical formulation
  • Receptacle for an aerosolizable pharmaceutical formulation

Examples

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Embodiment Construction

[0038] It is to be understood that, unless otherwise indicated, this invention is not limited to particular devices, architectures, formulation compositions, drug delivery systems, manufacturing techniques, administration procedures, etc., as these may vary. In this regard, unless stated otherwise, a reference to a compound or composition includes that compound or composition by itself, as well as compounds in combination with other compounds or compositions, eg, mixtures of compounds.

[0039] Before further description, the following definitions of terms will help to understand the embodiments of the present invention.

[0040] As used herein, the singular forms "a" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to "a phospholipid" includes a single phospholipid as well as two or more phospholipids in combination or in admixture unless the context clearly dictates otherwise.

[0041] References herein to "one e...

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Abstract

An article for storing a pharmaceutical formulation. In one or more embodiments, the present invention comprises a receptacle (125) for an aerosolizable formulation, the receptacle having a wall thickness of between about 100-235 microns, wherein the receptacle is puncturable to allow escape and dispersion of the formulation therein. Also provided are methods of aerosolizing formulations for inhalation, and systems for aerosolizing such formulations.

Description

Background technique [0001] The need for effective therapeutic treatment of patients has led to the development of various drug formulation delivery technologies. One conventional technique involves the oral delivery of pharmaceutical formulations in the form of pills, capsules, elixirs, and the like. However, oral delivery is not desirable in some situations. For example, many pharmaceutical preparations can deteriorate in the digestive tract before they can be effectively absorbed by the body. Inhalable drug delivery has proven to be a particularly effective and / or desirable alternative, wherein an aerosolized drug formulation is orally or nasally inhaled by a patient to deliver the formulation to the patient's airways. For example, in one inhalation technique, an aerosolized pharmaceutical formulation provides localized therapeutic relief to a portion of the respiratory tract, such as the lungs, to treat diseases such as asthma, emphysema, and cystic fibrosis. In another...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M11/02A61M15/00A61M11/06
CPCA61M15/0028A61M2015/0035A61J3/071A61M2206/16A61M2202/064A61M2015/0041A61M15/0008A61M15/0035A61M15/0041
Inventor S·谢乌L·占
Owner NOVARTIS AG
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