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Compound blood pressure lowering capsules for treating metabolic hypertension, preparation method and application thereof

A technology for hypertension and capsules, which is applied in the field of Chinese patent medicine and its preparation and application, can solve the problems of inconvenient medication, inability to effectively control metabolic disorders, and high economic costs, and achieve the effect that is beneficial to blood pressure

Inactive Publication Date: 2014-07-23
CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new technology can help reduce high levels of circulating plasma cholesterols (hyperchlorhydria) which may lead to cardiovascular disease by reducing their production or affecting certain enzymes involved in making them more effective. It also helps maintain stable blood sugar level through controlling insulin resistance.

Problems solved by technology

This patents discuss how metabolically significant individuals can develop complications related to their health conditions due to increased levels of lipids or other substances present within them called insulin resistance syndrome (IRS). These issues may lead to cardiac dysfunction if they don't manage properly during therapy. Traditional methods like lifestyle changes alone often result in adverse side effect profiles associated with these treatments. Therefore, there needs an effective way to prevent this phenomenon through pharmacotherapies.

Method used

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  • Compound blood pressure lowering capsules for treating metabolic hypertension, preparation method and application thereof
  • Compound blood pressure lowering capsules for treating metabolic hypertension, preparation method and application thereof
  • Compound blood pressure lowering capsules for treating metabolic hypertension, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Original drug preparation: Take 5g of Salvia miltiorrhiza, 10g of Achyranthes bidentata, 10g of Digupi, 10g of Eucommia, 5g of cassia seed, 10g of mulberry root, and 2g of green tea extract according to the prescription;

[0039] Preparation method embodiment one

[0040] Based on the raw materials described in Example 1, the preparation method Example 1 comprises the following steps:

[0041] (1) Alcohol extraction: Mix 5g of Salvia miltiorrhiza, 5g of cassia seed, 10g of Digupi and 10g of Achyranthes bidentata to obtain mixture A, which is refluxed and extracted twice with 60% ethanol solution. The mass is 8 times and 6 times, and the reflux extraction time of the two times before and after is 1h and 0.5h respectively; the final alcohol extract is concentrated in a vacuum until it has no alcohol smell, the temperature of the vacuum concentration is 50°C, and the vacuum degree is -0.1Mpa. Alcohol extraction concentrated solution for standby;

[0042] (2) Water extrac...

Embodiment 2

[0046] Original drug preparation: Take 8g of Salvia miltiorrhiza, 12g of Achyranthes bidentata, 12g of Digupi, 12g of Eucommia, 8g of cassia seed, 12g of mulberry root, and 5g of green tea extract according to the prescription;

Embodiment 2

[0048] Based on the raw materials described in Example 2, the preparation method Example 2 comprises the following steps:

[0049] (1) Alcohol extraction: Mix 8 g of Salvia miltiorrhiza, 8 g of cassia seed, 12 g of Digupi and 12 g of Achyranthes bidentata to obtain mixture A, which is refluxed and extracted twice with 70% ethanol solution. 10 times and 7 times the mass, the two reflux extraction times are 1.5h and 1h respectively; the final alcohol extract is concentrated in vacuum until it has no alcohol smell, the temperature of vacuum concentration is 60°C, and the vacuum degree is -0.1Mpa. Alcohol extraction concentrated solution for standby;

[0050] (2) Water extraction: Add 12 g of Eucommia Eucommia and 12 g of Sangjisheng to the medicinal residues after alcohol extraction in step (1) to obtain mixture B. The mixture B is extracted twice with water, and the amount of water added in the two water extractions is respectively 8 times and 5 times of the total mass of B, th...

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Abstract

The invention relates to compound blood pressure lowering capsules for treating metabolic hypertension, a preparation method and an application thereof, particularly to a preparation process of compound blood pressure lowering capsules for targeted treatments of various metabolic disorders of metabolic hypertension, wherein raw materials such as salvia miltiorrhiza bunge, obtuseleaf senna seed, cortex lycii, achyranthes bidentata blume, eucommia ulmoides and loranthus parasiticus are adopted, alcohol extraction is performed on the salvia miltiorrhiza bunge, the obtuseleaf senna seed, the cortex lycii and the achyranthes bidentata blume, the drug residue produced after alcohol extraction is added with the eucommia ulmoides and the loranthus parasiticus to carry out mixed water extraction, the alcohol extraction solution and the water extraction solution are subjected to concentration drying to prepare particles, and the particles are loaded into capsules so as to prepare the product Chinese patent medicine. According to the present invention, the compound blood pressure lowering capsules prepared by using the preparation process is designed based on various metabolic disorders of metabolic hypertension so as to stabilize the blood pressure, achieve blood sugar and blood fat metabolism, regulate metabolism, easily achieve blood pressure control, treat symptoms and root causes, and provide important significance for prevention and treatment of metabolic hypertension.

Description

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Claims

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Application Information

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Owner CENT SOUTH UNIV
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