Pharmaceutical composition for treating chronic obstructive pulmonary disease

Abstract

The invention provides a pharmaceutical composition for treating chronic obstructive lung disease. The pharmaceutical composition is characterized in that the prescription of the pharmaceutical composition contains the ingredients in parts by weight: 10-60 parts of raw milkvetch root, 10-35 parts of poria cocos, 10-30 parts of codonopsis pilosula, 10-35 parts of scutellaria root, 5-18 parts of fried atractylodes macrocephala, 5-18 parts of dried tangerine peel, 5-18 parts of angelica sinensis, 5-18 parts of balloon flower root, 5-15 parts of bulbus fritilariae, 5-15 parts of prepared liquorice root, 1-7 parts of rhizoma cimicifugae and 1-7 parts of loquat leaves. The pharmaceutical composition preparation is prepared from a traditional Chinese medicine composition and a pharmaceutically-acceptable carrier, and dosage forms comprise decoction, pills, capsules, granules, dissolved granules, tablets and oral liquid. The composition provided by the invention has the effects of invigorating the spleen to benefit the lung and resolving phlegm and dredging the collaterals, has a remarkable treatment effect on patients suffering from chronic obstructive pulmonary disease, and is free from toxic or side effects.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating chronic obstructive pulmonary disease. Background technique

[0002] Chronic obstructive pulmonary disease (COPD) is a destructive lung disease characterized by airflow limitation that is not fully reversible, usually progressive and harmful to the lungs Associated with an abnormal inflammatory response to particles or gases. COPD is a chronic airway inflammatory disease that can be prevented and treated. Although COPD is an airway disease, its systemic impact on the whole body cannot be ignored. Infection is one of the important factors for the occurrence and development of COPD. Viruses, bacteria and mycoplasma are important factors for the acute exacerbation of the disease. The viruses are mainly influenza virus, rhinovirus, adenovirus and respiratory syncytial virus, etc. Bacterial infections include Streptoco...

Examples

Embodiment 1

[0030] Example 1 Prescription and preparation method of composition granules of the present invention: 40 parts of raw Astragalus membranaceus, 25 parts of Poria cocos, 25 parts of Codonopsis radix, 20 parts of Scutellaria baicalensis, 10 parts of fried Atractylodes macrocephala, 10 parts of tangerine peel, 8 parts of angelica, 8 parts of bellflower, and Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted for 2 hours, 6 times of water addition, 2 times of decoction; combined the two filtrates, concentrated under reduced pressure to relative The density is 1.20-1.40 to obtain a water-extracted thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder. Add an appropriate proportion of excipients to the extract powder. The excipients are intended to be sucrose or lactose (mannitol, aspartame, stevios...

Embodiment 2

[0031] Example 2 Prescription and preparation method of composition granules of the present invention: 50 parts of raw Astragalus membranaceus, 35 parts of Poria cocos, 25 parts of Codonopsis radix, 15 parts of Scutellaria baicalensis, 5 parts of fried Atractylodes macrocephala, 5 parts of tangerine peel, 8 parts of angelica, 8 parts of platycodon, Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted for 2 hours, 6 times of water addition, 2 times of decoction; combined the two filtrates, concentrated under reduced pressure to relative The density is 1.20-1.40 to obtain a water-extracted thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder. Add an appropriate proportion of excipients to the extract powder. The excipients are intended to be sucrose or lactose (mannitol, aspartame, stevioside fo...

Embodiment 3

[0032] Example 3 Prescription and preparation method of composition granules of the present invention: 40 parts of raw Astragalus membranaceus, 25 parts of Poria cocos, 25 parts of Codonopsis radix, 20 parts of Scutellaria baicalensis, 10 parts of fried Atractylodes macrocephala, 10 parts of tangerine peel, 8 parts of angelica, 8 parts of bellflower, and Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted twice, the first decoction was 3 hours, and the multiple of water was 8 times, and the second decoction was 2 hours, and the multiple of water was 6 times; The two filtrates are combined, concentrated under reduced pressure to a relative density of 1.20-1.40 to obtain a water extract thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder . Add an appropriate proportion of excipients to the ex...

technical field

[0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating chronic obstructive pulmonary disease. Background technique

[0002] Chronic obstructive pulmonary disease (COPD) is a destructive lung disease characterized by airflow limitation that is not fully reversible, usually progressive and harmful to the lungs Associated with an abnormal inflammatory response to particles or gases. COPD is a chronic airway inflammatory disease that can be prevented and treated. Although COPD is an airway disease, its systemic impact on the whole body cannot be ignored. Infection is one of the important factors for the occurrence and development of COPD. Viruses, bacteria and mycoplasma are important factors for the acute exacerbation of the disease. The viruses are mainly influenza virus, rhinovirus, adenovirus and respiratory syncytial virus, etc. Bacterial infections include Streptoco...

Examples

Embodiment 1

[0030] Example 1 Prescription and preparation method of composition granules of the present invention: 40 parts of raw Astragalus membranaceus, 25 parts of Poria cocos, 25 parts of Codonopsis radix, 20 parts of Scutellaria baicalensis, 10 parts of fried Atractylodes macrocephala, 10 parts of tangerine peel, 8 parts of angelica, 8 parts of bellflower, and Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted for 2 hours, 6 times of water addition, 2 times of decoction; combined the two filtrates, concentrated under reduced pressure to relative The density is 1.20-1.40 to obtain a water-extracted thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder. Add an appropriate proportion of excipients to the extract powder. The excipients are intended to be sucrose or lactose (mannitol, aspartame, stevios...

Embodiment 2

[0031] Example 2 Prescription and preparation method of composition granules of the present invention: 50 parts of raw Astragalus membranaceus, 35 parts of Poria cocos, 25 parts of Codonopsis radix, 15 parts of Scutellaria baicalensis, 5 parts of fried Atractylodes macrocephala, 5 parts of tangerine peel, 8 parts of angelica, 8 parts of platycodon, Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted for 2 hours, 6 times of water addition, 2 times of decoction; combined the two filtrates, concentrated under reduced pressure to relative The density is 1.20-1.40 to obtain a water-extracted thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder. Add an appropriate proportion of excipients to the extract powder. The excipients are intended to be sucrose or lactose (mannitol, aspartame, stevioside fo...

Embodiment 3

[0032] Example 3 Prescription and preparation method of composition granules of the present invention: 40 parts of raw Astragalus membranaceus, 25 parts of Poria cocos, 25 parts of Codonopsis radix, 20 parts of Scutellaria baicalensis, 10 parts of fried Atractylodes macrocephala, 10 parts of tangerine peel, 8 parts of angelica, 8 parts of bellflower, and Chuanbei 8 parts, 10 parts of roasted licorice, 4 parts of Cimicifuga, 4 parts of loquat leaves, mixed with water and decocted twice, the first decoction was 3 hours, and the multiple of water was 8 times, and the second decoction was 2 hours, and the multiple of water was 6 times; The two filtrates are combined, concentrated under reduced pressure to a relative density of 1.20-1.40 to obtain a water extract thick paste; the thick paste is dried under reduced pressure at a drying temperature of 50-80°C, and then crushed through an 80-mesh sieve to obtain an extract powder . Add an appropriate proportion of excipients to the ex...