Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Continuous albumin dialysis and adsorption purification system and application thereof in child artificial liver

A purification system and albumin technology, applied in dialysis systems, suction equipment, blood filtration, etc., can solve the problems of not being suitable for children with small body weight, large extracorporeal circulation capacity, etc., to improve the level of treatment, good compatibility, and adjustable range big effect

Pending Publication Date: 2019-10-11
天津市第一中心医院
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems existing in the prior art, the present invention provides a continuous albumin dialysis adsorption purification system and its application in children's artificial liver to solve the problem that the existing artificial liver hybridization technology is not suitable for small body weight due to the large extracorporeal circulation capacity. children's problems

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Continuous albumin dialysis and adsorption purification system and application thereof in child artificial liver

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] The technical solution of the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0017] Dialyzers, adsorption columns, etc. used in the present invention are all conventional commercially available materials.

[0018] The present invention is a new artificial liver support system for children, a continuous albumin dialysis adsorption purification system (Continuous Albumin Dialysis and Absorption Purification System, CADAPS), including a blood circuit and an albumin regeneration loop, and the albumin regeneration loop is based on albumin dialysis The principle is that two adsorption columns (one broad-spectrum adsorption column 2 and one bilirubin adsorption column 3) are connected in series on the albumin dialysate channel to form a closed-loop albumin regeneration loop, which can efficiently remove protein binding in children with liver failure. toxin. The connecting pipeline is a standard int...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a continuous albumin dialysis and adsorption purification system and application thereof in a child artificial liver. The system comprises a blood loop and an albumin regeneration cycle loop; the blood loop comprises high-flux dialyzer which is connected with human body circulation, and the albumin regeneration cycle loop is sequentially connected with the high-flux dialyzer, a broad-spectrum adsorption column and a bilirubin adsorption column through a dialysis pipeline, and filled with albumin dialyzate. The blood dialysis loop has a small volume, and circulation instability caused when the in-vitro blood loop has a too large capacity can be avoided; through albumin regeneration cycle, protein binding toxins of children with hepatic failure can be efficiently removed, a blood dialysis and / or filtering system can be made sequential, and water-soluble medium and small molecular toxins are removed. The automatic selection range of consumables of the system is large, the albumin dialyzate can be recycled, the treatment cost for the child artificial liver is effectively lowered, the operational process is simple, and the working pressure of medical personnel can be effectively alleviated.

Description

technical field [0001] The invention relates to a non-biological artificial liver system for children. Background technique [0002] Artificial Liver Support System (ALSS), referred to as artificial liver, is an in vitro support system that temporarily replaces part of the liver's functions. Through mechanical, physical, chemical and biological devices outside the body, it removes various harmful substances, supplements essential substances, and improves To create conditions for the recovery of liver function, or as a bridge before liver transplantation. Artificial livers are divided into non-biological artificial livers, biological artificial livers and hybrid artificial livers. Non-biological artificial liver technology essentially belongs to the category of blood purification technology. Based on the basic principles of blood purification of diffusion, convection and adsorption, a series of artificial liver technologies have been developed, including plasma exchange, pla...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/16A61M1/34
CPCA61M1/16A61M1/1676A61M1/34
Inventor 王卫利
Owner 天津市第一中心医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products