86results about How to "Guaranteed normal treatment" patented technology

The invention relates to a system and method for monitoring an engineering project operation site. The system comprises an information collecting device, a local area network router and a background server. The information collecting device is connected with the local area network router in a wireless mode, collects project site video and picture information, device information and worker's body information, and sends the information to the local area network router. The local area network router is connected with the information collecting device and the background server, receives the project site video and picture information, the device information and the worker's body information sent by the information collecting device and sends the information to the background server. The background server is connected with the local area network router, receives the project site video and picture information, the device information and the worker's body information sent by the local area network router and performs checking and supervision. The human cost can be reduced, the goal of supervising the operation site is achieved, the supervision efficiency is improved, the safety of the operation site is guaranteed to the largest degree, and the potential risk is eliminated.

The invention discloses a lymphoblastic leukemia CAR-T (Chimeric Antigen Receptor-T Cell Immunotherapy) therapy carrier based on an OCTS (One CAR with Two SeFvs) technology. The lymphoblastic leukemia CAR-T therapy carrier comprises a lentivirus skeleton plasma, a human EF1alpha promoter, an OCTS chimeric receptor structural domain and an IL6R single-chain antibody, wherein the OCTS chimeric receptor structural domain comprises a CD8 leader chimeric receptor signal peptide and two groups of single-chain antibodies; the first group of single-chain antibodies is selected from any one of the following four groups of single-chain antibodies: a CD20 single-chain antibody light chain VL and a CD20 single-chain antibody heavy chain VH, a CD22 single-chain antibody light chain VL and a CD22 single-chain antibody heavy chain VH, a CD30 single-chain antibody light chain VL and a CD30 single-chain antibody heavy chain VH, and a CD123 single-chain antibody light chain VL and a CD123 single-chain antibody heavy chain VH; and the second group of the single-chain antibodies is a CD19 single-chain antibody light chain VL and a CD19 single-chain antibody heavy chain VH, an antibody Inner-Linker, a single-chain antibody Inter-Linker, a CD8-Hinge chimeric receptor linker, a CD8 Transmembrane chimeric receptor transmembrane zone, a TCR (T Cell Receptor) chimeric receptor T cell activation domain and a chimeric receptor co-stimulator zone. Besides, the invention discloses a constructing method for the carrier and application of the carrier to preparation of a drug for treating lymphoblastic leukemia.

The invention discloses a detection method of Guwei collaterals-activating tincture. A method for effectively detecting main drugs of the Guwei collaterals-activating tincture is added in the prior production process so that the main drug components of the finished production of the Guwei collaterals-activating tincture can be ensured relatively, thereby the monitoring level of the product quality is greatly improved. The invention is not only convenient for the product monitoring of manufacturers and management departments, but also can provide better guarantees for medical departments and the treatment of patients.

The invention discloses a CAR-T (Chimeric antigen receptor T-cell immunotherapy) therapeutic vector for T lymphocytic leukemia. The therapeutic vector comprises a lentivirus skeleton plasmid, a humanEF1 alpha promoter and a CAR chimeric receptor domain, wherein the CAR chimeric receptor domain contains CD8 leader chimeric acceptor signal peptide, a CD7 single-chain antibody light chain VL, a CD7single-chain antibody heavy chain VH, an antibody inner hinge UCLinker, a CD8 Hinge chimeric receptor hinge, a CD8 Transmembrane chimeric receptor transmembrane region, a TCR chimeric receptor T cellactivation domain and a chimeric receptor co-stimulatory factor region. The invention further discloses a construction method of the vector and an application of the vector in preparation of a drug for treating T lymphocytic leukemia.

The invention discloses a mass detection method of Kesuting syrup, which improves TLC identification to white mulberry root-bark and pink reineckea herb on the basis of the existing quality standard,increases the content limitation of morphine in poppy shell, and enhances the content limitation of ephedra herb, thus leading the level of monitoring the quality of Kesuting syrup to be greatly improved. The application of the mass detection method not only is more beneficial to the monitoring on products by manufacturers and regulatory authorities, but also provides better guarantee for treatment of medical authorities and patients.

The invention discloses a radiation shield door special for a radiology department. The radiation shield door comprises an observation window outer frame, a radiation shield door frame, a radiation shield door shell and a radiation shield door main board; the radiation shield door frame is internally provided with the radiation shield door shell which is provided with the observation window outer frame, the observation window outer frame is internally provided with an observation window, and a sealing vertical bar is arranged on the left side of the observation window; an existing radiation shield door is provided with a radiation detector and an automatic lock cylinder, when radioexamination treatment is conducted in a radiation room or radiation in the radiation room exceeds the standard, the radiation shield door can be locked automatically outside, the radiation shield door is further provided with a radiation shield blue-violet coating film and a double-layer protective sealing ring which are used for reducing leakage of radiation, the radiation shield door is provided with an observation window and an isolating baffle, the isolating baffle can be utilized for covering and opening the observation window, medical personnel or family members can observe and visit patients conveniently, and therefore the purpose that use is safer and more convenient is achieved.

The invention discloses compound alpha-keto acid tablets and a preparation method and a detection method thereof. The preparation method comprises the following steps of: taking calcium 3-methyl-2-oxovalerate, ketoleucine calcium, alpha-ketophenylalanine calcium, keto-valine-calcium, D,L-alpha-hydroxymethionine calcium, lysine acetate, threonine, tryptophan, histidine and tyrosine, crushing the main medicaments respectively and sieving with a sieve of 100 meshes; sieving starch, talc powder and magnesium stearate and sieving with a sieve of 80 meshes respectively; mixing the main medicaments and the starch uniformly, preparing a soft material from 6 percent polyvinyl pyrrolidone (PVP) k30 isopropanol solution, granulating with a sieve of 20 meshes, and drying at the temperature of 40 DEG C; reshaping, adding magnesium stearate, the talc powder and crosslink povidone, and mixing uniformly; detecting an intermediate, and tabletting; and coating, and thus obtaining the compound alpha-keto acid tablets. The tablets with excellent granule pressing property, flowability, hardness and dissolution degree can be prepared by using the method, and the detection method can further ensure the quality of the prepared compound alpha-keto acid tablets.

The invention discloses a biological self-feedback sleep monitoring magnetic therapy apparatus. According to the sleep monitoring magnetic therapy apparatus, multiple physiological data are acquired by a physiological parameter monitoring system, transmitted to an upper computer system through an external extension interface and fed back to a lower computer system in real time so that a magnetic field can be adjusted; the lower computer system comprises a single-chip microcomputer control circuit, a magnetic field generating circuit and a plurality of coils, a therapeutic scheme is transmitted to the single-chip microcomputer control circuit by the upper computer system, the therapeutic scheme is converted into pulse signals by the single-chip microcomputer control circuit and stored, and charging and discharging of the magnetic field generating circuit are controlled by the pulse signals, so that the coils can generate 0-40 Hz pulse magnetic fields different in intensity and adjustable in frequency. The magnetic stimulation mode is adopted in the therapeutic process, the magnetic field modes are flexible, changeable and adjustable, the multiple physiological data of a patient measured through an instrument can be fed back to the upper computer system in real time so as to adjust magnetic field changing modes and adapt to the current physiological state of the patient, and therefore the patient can be fast induced to sleep.

The invention discloses a method for detecting gastrodia elata and lucid ganoderma granules. The medicine is mainly prepared from gastrodia elata, lucid ganoderma, processed rhizoma polygonati, herba epimedii and processed radix polygonum multiflorum preparata. The detection method comprises thin-layer chromatography identification of gastrodia elata, herba epimedii and / or lucid ganoderma, and content determination of gastrodin and / or icariin. The detection method is accurate, high in sensitivity, good in repeatability and stable in detection result; the quality of the gastrodia elata and lucid ganoderma granules can be effectively detected; and the curative effect of the medicine can be ensured by the test item standard.

The invention relates to the technical field of medical appliance, in particular to a photosensitive drug dosing bracket used for curing uterine neck pathological changes, which provides a dosing bracket used for uterine necks and comprises a support structure with a coating on the surface. The bracket is characterized in that the coating contains photosensitive substance. The dosing bracket used for uterine neck pathological changes can be attached with the uterine necks in compliance so as to ensure that photodynamic therapy medicine can be continuously released on focus parts. The dosing bracket is convenient for the use of medical personnel and improves the comfort of patients.

The invention discloses an OCTS technology-based pancreatic cancer and malignant mesothelioma CAR-T therapy vector. The vector comprises lentivirus framework plasmid, a human EF1alpha promoter (SEQ ID NO. 14), an OCTS chimeric receptor structural domain and a PDL1 single-chain antibody; the OCTS chimeric receptor structural domain comprises CD8 leader chimeric receptor signal peptide (SEQ ID NO. 15), a PDL1 single-chain antibody light chain VL (SEQ ID NO. 16), a PDL1 single-chain antibody heavy chain VH (SEQ ID NO. 17), an MESOTHELIN single-chain antibody light chain VL (SEQ ID NO. 18), an MESOTHELIN single-chain antibody heavy chain VH (SEQ ID NO. 19), an antibody inner linker Inner-Linker (SEQ ID NO. 20), a single-chain antibody inter-linker Inter-Linker (SEQ ID NO. 21), a CD8 Hinge chimeric receptor linker (SEQ ID NO. 22), a CD8Transmembrane chimeric receptor transmembrane domain (SEQ ID NO. 23), a TCR chimeric receptor T-cell activation domain (SEQ ID NO. 26), and a chimeric receptor inducible co-stimulater area. In addition, the invention also discloses a construction method of the vector as well as application of the vector to preparation of medicines for treating pancreatic cancer and malignant mesothelioma.

The invention provides a liquid level automatic alarm device in medical transfusion. The device is characterized in that the device comprises a power supply, an LED1 indicating lamp, a sound-light alarm module, a pulse frequency detection module, a capacitance liquid level sensor, a single-chip microcomputer, and a reset key. The device does not pollute solution, and is good in reliability, low in cost, and simple and convenient in installation operation. The device can rapidly and accurately determine that the solution is completely transfused, and gives out a sound-light alarm signal to prompt a nurse to dispose in time, thereby greatly reducing the number that a nurse rushes about back and forth, reducing labor intensity of the nurse and cost of looking after a patient, and reducing psychological burdens. The device has better guarante for treatment of patients.

The invention discloses a respirator mask. The respirator mask is characterized by comprising an exhaust tube, a sterilizing container, a gas inlet tube, a flow adjusting valve, a shell, a lower jaw support, a nose bridge support, a surrounding air bag and a respiration tube. The respirator mask is simple in structure, the position of the respirator mask on the head of a patient can be automatically corrected, and the treatment of the patient is guaranteed. In the correction process, the nose bridge support and the lower jaw support which exert correction pressure are each of an air bag structure and can not form injuries on the face of the patient. Meanwhile, since the surrounding air bag and the edge of the mask exert pressure on the face of the patient alternately to massage the face ofthe patient, there is no need to worry that the edge of the mask presses on the face of the patient all the time and causes local long-term ischemia injuries to the face of the patient; by arrangingthe sterilizing container, the mask is safer to use, it is avoided that gas exhaled by some patients suffering from infectious respiratory diseases contaminates the surrounding environment and cross infection is caused.

The present invention relates to a laser therapeutic head for curing angioma. It includes a shell body, and is characterized by that in the shell body is fixedly mounted a lens capable of making laser beam focused focal distance be 6-9cm, one end of the shell body is connected with laser outlet end of laser generation device, on another end of said shell body a telescopical knife nose is mounted, and on the laser beam outlet end of said telescopical knife nose is set a positioning bar which is conveniently observed by operator, and the length of the telescopical knife nose must make the diameter of laser facula formed in the top end of said positioning bar be 3-7mm.

The invention discloses an OCTS technology-based prostatic cancer CAR-T therapy vector which comprises a lentivirus framework plasmid, a human EP1alpha promoter (SEQ ID NO.14), an OCTS chimeric receptor structure domain and a PDL1 single-chain antibody, wherein the OCTS chimeric receptor structure domain comprises A CD8 leader chimeric receptor signal peptide (SEQ ID NO.15), a PSMA single-chain antibody light chain VL (SEQ ID NO.16), a PSMA single-chain antibody heavy chain VH (SEQ ID NO.17), a PDL1 single-chain antibody light chain VL (SEQ ID NO.18), a PDL1 single-chain antibody heavy chain VH (SEQ ID NO.19), an antibody Inner-Linker (SEQ ID NO.20), a single-chain antibody Inter-Linker (SEQ ID NO.21), a CD8 Hinge chimeric receptor hinge (SED ID NO.22), a CD8 Transmembrane chimeric receptor transmembrane domain (SEQ ID NO.23), a TCR chimeric receptor T cell activation domain (SEQ ID NO.26) and a chimeric receptor co-stimulus factor domain. In addition, the invention further discloses a construction method of the vector and an application of the vector in preparation of drugs for treating a prostatic cancer.

The invention discloses a myeloid leukemia CAR-T treatment carrier based on an OCTS technology. The myeloid leukemia CAR-T treatment carrier based on the OCTS technology comprises lentivirus framework plasmids, a human EF1 alpha promoter (SEQ ID NO. 14), an OCTS chimeric receptor structural domain and a PDL1 single-chain antibody; the OCTS chimeric receptor structural domain comprises a CD8 leader chimeric receptor signal peptide (SEQ ID NO. 15), a CD33 single-chain antibody light chain VL (SEQ ID NO. 16), a CD33 single-chain antibody heavy chain VH (SEQ ID NO. 17), a CD123 single-chain antibody light chain VL (SEQ ID NO. 18), a CD123 single-chain antibody heavy chain VH (SEQ ID NO. 19), an antibody Inner-Linker (SEQ ID NO. 20), a single-chain antibody Inter-Linker (SEQ ID NO. 21), a CD8 Hinge chimeric receptor hinge (SEQ ID NO. 22), a CD8 Transmembrane chimeric receptor region (SEQ ID NO. 23), a TCR chimeric receptor T cell activation domain (SEQ ID NO. 26) and a chimeric receptor co-stimulatory factor region. In addition, the invention further discloses a construction method of the carrier and application of the carrier in preparation of drugs for treating myeloid leukemia.

The invention discloses a detecting chip, making and detecting method of relative gene of salvia miltiorrhizae, which is characterized by the following: setting astopic probe on the glass to make gene chip; crossing with cDNA of marked sample of salvia miltiorrhizae; scanning result; analyzing expressive quantity of relative gene of salvia miltiorrhizae; fitting for obtaining functional information to pave the base to study salvia miltiorrhizae.

The invention discloses a CAR-CIK transgenic cell. The CAR-CIK transgenic cell includes a chimeric antigen receptor CAR gene targeting a CD19 antigen, a CD56 cell and a CD3 cell, wherein the CAR gene,the CD56 cell and the CD3 cell are all positive in expression. The invention also discloses a preparation method of the CAR-CIK transgenic cell. The preparation method includes the following steps: step 1, isolating a peripheral blood mononuclear cell (PBMC); step 2, activating a CIK cell; step 3, adding a hCAR19 lentivirus transgenic vector targeting the CD19 antigen for transduction and performing CAR-CIK cell induction culture; and step 4, carrying out amplification in vitro on the CAR-CIK cell to obtain the CAR-CIK transgenic cell. The invention also discloses an application of the CAR-CIK transgenic cell in the preparation of tumor cell therapy medicines. Compared with a CAR-T cell, the CAR-CIK transgenic cell is higher in killing efficiency and wider in killing range.

The invention relates to a soft capsule for improving the cranial nerve function and a preparation method thereof. The soft capsule comprises content and a capsule shell material; the content comprises glyceryl phosphoryl choline and a solvent, wherein the glyceryl phosphoryl choline accounts for 60-95% of the total weight of the content; the solvent accounts for 5-40% of the total weight of the content; the solvent comprises one or several of water, glycerol, sorbitol, sorbitan, glycerol triacetate, polyethylene glycol 200, polyethylene glycol 400 and propylene glycol; and the capsule shell material comprises one or several of gelatin, water, glycerol, sorbitol, sorbitan, methylparaben, ethylparaben, propylparaben, titanium dioxide and iron oxide yellow. The preparation method comprises the following steps of: pressing a solution A prepared by the glyceryl phosphoryl choline and the solvent and a solution B prepared by the capsule shell material into soft capsules by a soft capsule machine; and drying to obtain the soft capsule for improving the cranial nerve function.

The invention discloses a detection method for heat-clearing and stasis-removing drugs. The detection method comprises a content determination method; and the content determination method comprises a step of determination of the content of hyperoside. The detection method has the advantages of accuracy, high sensitivity, good repeatability and stable detection results and can effectively detect the quality of the heat-clearing and stasis-removing drugs; and standard of each detection item can guarantee curative effects of the drugs.

The invention discloses a nursing monitoring system and a nursing monitoring method. The nursing monitoring system comprises a background server, nursing monitoring equipment, a receiving terminal and environment monitoring adjusting equipment. The nursing monitoring equipment is used for acquiring physical health indexes of a patient in real time and transmitting the physical health indexes to the background server; the background server analyzes the physical health indexes to rate the health state of the patient; the environment monitoring adjusting equipment is used for detecting ward environment indexes and intelligently adjusting the patient environment according to the detected environment indexes and the health state rating of the patient; and the receiving terminal is used for receiving the body health indexes of the patient, the health state rating and the ward environment indexes sent by the background server. The nursing monitoring system and the nursing monitoring method implement real-time monitoring on the physical health state of the patient, is convenient to rapidly determine the reason of the dangerous condition, is convenient to know the physical state of the patient in each period, and ensures that the patient is treated and has a rest in an environment most suitable for the physical state of the patient.

The invention discloses an air flowing bed. The air flowing bed comprises an upper bed body and a lower bed body, and further comprises a side frame, wherein a filter unit, a fluidization cabin, a permeable plate and a high-pressure cabin are arranged in the upper bed body from top to bottom in sequence; a control system as well as an air inlet system, a temperature control system and a weighing system which are electrically connected with the control system are arranged in the lower bed body; the side frame comprises a foundation bed, and further comprises an elastic pressure strip, the two ends of the foundation bed respectively extend up and down to form an upper clamping ring I, a lower clamping ring I, an upper clamping ring II and a lower clamping ring II; an upper clamping slot is formed by the upper clamping ring I, the upper clamping ring II and the foundation bed; a lower clamping slot is formed by the lower clamping ring I, the lower clamping ring II and the foundation bed; the fluidization cabin and the upper bed body are clamped by the lower clamping slot; a thread gluing ring belt is arranged at one side of the upper clamping ring II; the filter unit is bonded with the thread gluing ring belt; the elastic pressure strip is embedded into the upper clamping slot and used for tightly pressing the periphery of the filter unit between the upper clamping slot and the elastic pressure strip. According to the air flowing bed disclosed by the invention, the air flowing bed has the technical effects that the thread gluing ring belt is arranged on the upper clamping ring II, the filter unit is fixed by the elastic pressure strip, micro particles in the fluidization cabin are not prone to run off, and a patient is enabled to be treated under a clean environment.

The invention belongs to the technical field of medical appliances and discloses internet-based gynecological oncology nursing monitoring early-warning system and early-warning method. The early-warning system is provided with a bed body, wherein a support is fixed to the bottom of the bed body through nuts. A first pulley is connected to the support. A three-hole socket is formed on one side of the bed body. A sliding rail is arranged on the edge of one side of the bed body and is provided with a second pulley. A buzzer alarm is arranged on the end of the bed body. A telephone voice alarm isconnected to one side of the buzzer alarm through a data line. A tumor detector is fixed to the bed body and can slide along the sliding rail. The processors work in the transmission mode of GPRS wireless connection. The early-warning system and early-warning method have high detection precision, so that a doctor can know the body status and tumor development tendency of patients in real time, thus making great assistance to treatment on the patients.

The invention relates to a device for physically treating drinking water, in particular, for reducing the formation of limestone. The invention device comprises at least one water inlet (3b) and at least one water outlet (3c), whereby the device is mounted in the cold water supply line (3) of at least one water heater (1), preferably a boiler, and the device is placed in good heal-conductive thermal contact with the hot water area of the water heater (1).

The invention discloses a high-precision drug delivery device based on respiratory medicine, which includes a base, an outer box is fixedly connected to the top of the base, and a drawer device is slidably connected to the inside of the outer box. A first manual control switch and a second manual control switch are fixedly connected, and a support device is fixedly connected to one side of the top of the outer box. The drug delivery device based on the high degree of precision used in the respiratory department solves the great shortage in the use process and ensures that when the drug delivery tube enters the patient's throat, the medical staff can accurately judge the spraying head of the drug delivery tube. The location avoids the accuracy of spraying medicine, reduces the waste of medicine, ensures the normal treatment of patients, shortens the treatment time of patients, and avoids the problem of no corresponding storage of medicines and instruments for respiratory medicine. It is more convenient for medical personnel to use and search.

The invention relates to the technical field of computer application, and particularly to a diabetes Internet community tracking follow-up surveying management method and a system. The diabetes Internet community tracking follow-up surveying management method comprises the steps of S10, if a community follow-up surveying request message which is triggered by a patient is acquired, acquiring a patient identification form the community follow-up surveying request message; S20, establishing a database which corresponds with the patient identification, and marking the database by means of the patient identification; S30, according to a preset time period, transmitting a follow-up surveying communication request according to the patient identification, acquiring patient condition data accordingto the follow-up surveying communication request; and S40, acquiring the patient nourishing plan according to the patient identification, and generating a patient nourishing replacement plan according to the patient condition data. The diabetes Internet community tracking follow-up surveying management method and the system has an advantage of facilitating in-time medicine and nourishing plan adjustment by the diabetes patient.