The invention discloses an intelligent radiation isolating double-roller-shuttle fireproof door. The door comprises an electric control device, an opening-closing machine, a scroll, a shell, a door body and rails. The scroll arranged in the shell is connected with the opening-closing machine, two groups of rails are fixed on the inner wall of a door stop, and the upper ends of the vertical rails on two sides support the two ends of the shell. The electric control device is provided with manual and intelligent control systems; and the intelligent control system outputs rated values to automatically control the operation of the opening-closing machine according to a smoke sensing probe, a temperature sensing probe and a temperature control member. Gaps of two sides of the oblong door body are inserted into open slots of the rails, and the upper end of the door body is connected with a switching mechanism to form a follow-up winding mechanism. The door body has a multilayer structure, wherein the front is provided with glass fiber decorative cloth, the second layer is provided with fireproof cloth, the third layer is provided with an aluminum silicate fireproof fiber felt, and the back is provided with radiation-proof cloth. Because multilayer fibers form the soft door body, the door has light weight, is convenient to open and close, and more importantly, can be automatically closed to regionally block a fire source when a fire breaks out under unmanned supervision. The door prevents fire and radiation, and is particularly suitable for public escape passages.