A colloid micropipette for bone marrow cavity injection

Abstract

The present invention discloses a colloid micro-injector for intramedullary injection, which belongs to the technical field of colloid injection, and comprises a lateral dosing intramedullary puncture hollow needle, a piston rod, a lateral dosing tube and a dosing push rod, wherein the front end of the lateral dosing intramedullary puncture hollow needle is an oblique puncture shape, the piston rod is arranged inside the lateral dosing intramedullary puncture hollow needle and slides with the lateral dosing intramedullary puncture hollow needle, the lateral dosing tube is in an inclined state and is connected to the lateral dosing intramedullary puncture hollow needle, the dosing push rod is a solid structure, the dosing push rod is arranged inside the lateral dosing tube and slides with the lateral dosing tube, and the front end of the piston rod and the front end of the dosing push rod are provided with a piston sealing rubber ring. The present invention provides a colloid micro-injector for intramedullary injection, which can inject colloids with high viscosity and is conducive to the uniform distribution of drugs.

Description

Technical Field

[0001] The invention relates to a colloid micro-injector for mouse bone marrow cavity injection, which is used for adding micro-volume substances and belongs to the technical field of colloid substance injection. Background Art

[0002] The existing micropipette for intramedullary injection is mostly suitable for liquids and low-viscosity colloid solutions. The disadvantage is that due to the limitation of the pinhole diameter, the colloid with high viscosity cannot be injected when micro-injecting. In animal experimental research, intramedullary colloid solution injection is often used, but there is currently no effective device to meet the current injection needs.

[0003] For example, the bone marrow extraction and / or injection device disclosed in Chinese patent CN1909846A comprises a hand-held area, a needle with at least one side hole, and a protective cover covering at least part of the needle, wherein the protective cover is movably mounted relative to the needle between a blocking position of the at least one side hole and an opening position of the at least one side hole. This technical solution is dedicated to preventing any microbial contamination of the bone marrow, but the traditional injection needle used therein cannot solve the problem of being unable to inject high-viscosity colloids.

[0004] For another example, Chinese patent CN107875483A discloses an intramedullary injection device, including a syringe body, a cap, a push rod, and a fixed connection seat. The bottom of the syringe body is connected to an injection needle through a fixed connection seat, the top of the syringe body is connected to the bottom of the push rod through a piston, the top of the push rod is connected to a cap, the injection needle is a multi-stage connection, the side of the injection needle is evenly provided with inwardly recessed through holes, and a liquid-controlled one-way valve is provided in the syringe body. By designing a multi-stage connection and through holes on the injection needle, bone marrow injection can be achieved for tissues of different depths. It also does not solve the technical problem of being unable to inject colloids with high viscosity. Summary of the invention

[0005] The purpose of the present invention is to provide a colloid micro-pipette for intramedullary injection to solve the above technical problems.

[0006] The present invention provides a colloid micro-injector for intramedullary injection, comprising a lateral medication intramedullary puncture hollow needle, a piston rod, a lateral medication tube and a medication push rod, wherein the lateral medication intramedullary puncture hollow needle is a hollow structure, and the front end of the lateral medication intramedullary puncture hollow needle is an oblique puncture shape, the piston rod is a solid structure, the piston rod is arranged inside the lateral medication intramedullary puncture hollow needle and is slidably matched with the lateral medication intramedullary puncture hollow needle, the lateral medication tube is a hollow structure, the lateral medication tube is connected to the lateral medication intramedullary puncture hollow needle in an inclined state, the medication push rod is a solid structure, the medication push rod is arranged inside the lateral medication tube and is slidably matched with the lateral medication tube, and a piston sealing rubber ring is provided at the front end of the piston rod and the front end of the medication push rod.

[0007] Furthermore, the rod body of the medicine adding push rod is provided with scales.

[0008] Furthermore, the lateral medicated intramedullary puncture hollow needle is provided with a plurality of fish-scale-like barbed holes, and the plurality of fish-scale-like barbed holes are arranged in two holes symmetrically around the circumference and in an array.

[0009] Compared with the prior art, the beneficial effects of the present invention are:

[0010] Firstly, the piston rod of the present invention is pushed into the puncture needle, which is convenient for clearing the debris in the puncture needle. The inner cavity of the puncture needle is conducive to the micro-injection of high-viscosity colloids. The piston rod pushes the drug to the distal end of the lateral dosing medullary cavity puncture hollow needle. The lateral fish scale-like barbed holes and the distal oblique puncture needle head can both have drug penetration, which is conducive to the uniform distribution of the drug and can smoothly complete the micro-injection of high-viscosity colloids. The injection volume is easy to control, the operation is simple, the difficulty is low, and the experimental time consumption is reduced.

[0011] Secondly, the fish scale-like barbed hole of the present invention has the effect of expanding the medullary cavity when rotating clockwise into the medullary cavity, and has the effect of compacting the debris in the medullary cavity when rotating counterclockwise out, so that the medullary cavity is conducive to the micro-injection of high-viscosity colloid. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0013] Figure 1 The three-dimensional structure of the present invention is shown in FIG. Figure 1 ;

[0014] Figure 2 for Figure 1 Enlarged view of point A in the middle.

[0015] Reference numerals:

[0016] A hollow needle for puncturing the lateral medullary cavity for dosing medication 1, a piston rod 2, a lateral medullary cavity for dosing medication 3, a dosing injection rod 4, fish scale-like barbed holes 5, and a scale 6. DETAILED DESCRIPTION

[0017] The technical solution of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0018] The components of the embodiments of the present invention generally described and shown in the drawings herein may be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention.

[0019] Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative work shall fall within the scope of protection of the present invention.

[0020] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0021] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0022] Combine the following Figure 1 to Figure 2As shown, an embodiment of the present invention provides a colloid micro-injector for intramedullary injection, comprising a lateral medication intramedullary puncture hollow needle 1, a piston rod 2, a lateral medication tube 3 and a medication push rod 4, wherein the lateral medication intramedullary puncture hollow needle 1 is a hollow structure, and the front end of the lateral medication intramedullary puncture hollow needle 1 is an oblique puncture shape, the piston rod 2 is a solid structure, the piston rod 2 is arranged inside the lateral medication intramedullary puncture hollow needle 1 and is slidably matched with the lateral medication intramedullary puncture hollow needle 1, the lateral medication tube 3 is a hollow structure, the lateral medication tube 3 is connected to the lateral medication intramedullary puncture hollow needle 1 in an inclined state, and the medication push rod 4 is Solid structure, the dosing push rod 4 is arranged inside the lateral dosing tube 3 and slidably cooperates with the lateral dosing tube 3, and the front end of the piston rod 2 and the front end of the dosing push rod 4 are provided with a piston sealing rubber ring; the piston rod 2 is pushed into the puncture needle, which is convenient for emptying the debris in the puncture needle, and the inner cavity of the puncture needle is conducive to the micro-injection of high-viscosity colloids. The piston rod 2 pushes the drug into the distal end of the lateral dosing medullary cavity puncture hollow needle 1, and the lateral fish scale-like barbed hole 5 and the distal oblique puncture needle head can both have drug penetration, which is conducive to the uniform distribution of the drug, and can smoothly complete the micro-injection of high-viscosity colloids. The injection volume is easy to control, the operation is simple, the difficulty is low, and the experimental time is reduced.

[0023] The side dosing tube 3 is made of transparent material, which is convenient for observing the state of the colloid in the tube and controlling the added dosage. The rod body of the dosing push rod 4 has a scale 6; there is a scale 6 on the dosing push rod 4, each time one grid is pushed in, the length is about 2mm, and about 1.5ul of the colloid drug enters the puncture needle. The maximum pushing depth each time is 8mm, about 6ul; use the piston rod 2 to push the colloid drug into the distal end.

[0024] The lateral medicated medullary cavity puncture hollow needle 1 is provided with a plurality of fish-scale-like barbed holes 5, and the plurality of fish-scale-like barbed holes 5 are arranged in two holes symmetrically in a circle and in an array; the fish-scale-like barbed holes 5 can expand the medullary cavity when rotated clockwise, and can compact the debris in the medullary cavity when rotated counterclockwise, so that the medullary cavity is conducive to the micro-injection of high-viscosity colloid.

[0025] The use steps of the present invention are as follows: first, use the lateral medicated intramedullary puncture hollow needle 1 to perform intramedullary puncture, after the intramedullary cavity is broken, enter the cavity clockwise, and after reaching the puncture depth, rotate counterclockwise to half of the distance; the fish scale-like barbed hole 5 is rotated clockwise to expand the intramedullary cavity, and rotated counterclockwise to compact the debris in the intramedullary cavity; after the depth is satisfactory, use the piston rod 2 to push, push the piston rod 2 into the lateral medicated intramedullary puncture hollow needle 1, empty the debris in the puncture needle, and withdraw the piston rod 2; from the side Solid drugs are added to the dosing tube 3, and the dosing push rod 4 is used to push the drugs into the lateral dosing medullary cavity puncture hollow needle 1; the piston rod 2 is used to push the drugs into the distal end of the lateral dosing medullary cavity puncture hollow needle 1, and the drugs can penetrate both the lateral and distal ends, which is conducive to the uniform distribution of the drugs; there are scales 6 on the dosing push rod 4, and each push-in grid is about 2mm in length, and about 1.5ul of drugs enter the puncture needle. The maximum push-in depth each time is 8mm, about 6ul; the piston rod 2 is used to push the drugs to the distal end.

[0026] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A colloid micropipette for intramedullary injection, characterized in that: The invention comprises a lateral medicated medullary cavity puncture hollow needle (1), a piston rod (2), a lateral medicated medullary cavity puncture tube (3) and a medicated injection rod (4), wherein the lateral medicated medullary cavity puncture hollow needle (1) is a hollow structure, the front end of the lateral medicated medullary cavity puncture hollow needle (1) is an oblique puncture shape, the piston rod (2) is a solid structure, the piston rod (2) is arranged inside the lateral medicated medullary cavity puncture hollow needle (1) and is slidably matched with the lateral medicated medullary cavity puncture hollow needle (1), the lateral medicated medullary cavity puncture tube (3) is a hollow structure, and the lateral medicated medullary cavity puncture tube (3) is an inclined shape. The lateral medication dosing medullary cavity puncture hollow needle (1) is connected to the lateral medication dosing medullary cavity puncture hollow needle (1), the medication dosing push rod (4) is a solid structure, the medication dosing push rod (4) is arranged inside the lateral medication dosing tube (3) and is slidably matched with the lateral medication dosing tube (3), and the front end of the piston rod (2) and the front end of the medication dosing push rod (4) are provided with a piston sealing rubber ring; the lateral medication dosing medullary cavity puncture hollow needle (1) is provided with a plurality of fish scale-like barbed holes (5), and the plurality of fish scale-like barbed holes (5) are respectively arranged in two holes symmetrically in a circumferential direction and arranged in an array; the colloid is a colloid with high viscosity.

2. A colloid micropipette for intramedullary injection according to claim 1, characterized in that: The body of the dosing injection rod (4) is provided with a scale (6), and each time a scale is pushed in, the length is 2 mm, and the colloid entering the hollow needle for puncturing the lateral dosing medullary cavity is 1.5 ul.

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