Automatic column extraction and sealing device for online drug analysis equipment

Abstract

The invention discloses an automatic column taking and sealing device for online drug analysis equipment, comprising a bottom plate, a vertical plate, an retrieval device, a column pushing device, a column changing device, and a column pressing device. The vertical plate is installed on the bottom plate. The retrieval device comprises a filter column box, a filter column, a column taking slide, and a gear lever. The column taking slide is used to control the movement of the gear lever. The column pushing device comprises a supporting seat, a column pushing motor, a slider, and a sensor component. The sensor component is used to sense a signal that the filter column is in place and control the pushing of the column pushing motor. The column changing device comprises a turntable, a turntable motor seat, and a limit component. The limit component is used to sense the position of the turntable and control the rotation of the turntable motor seat. The column pressing device comprises a press column slide, a press column lock seat, a sealing column, and a sealing ring. The press column slide is used to control the movement of the press column lock seat. The setting of the sealing ring ensures the sealing of the liquid when passing through the column, improves the safety of the equipment, and the automatic column taking of the equipment is achieved through the cooperation of the four devices, thereby improving the efficiency of drug analysis.

Description

Technical Field

[0001] The present invention relates to the technical field of drug detection, and in particular to an automatic column taking and sealing device for online drug analysis equipment. Background Art

[0002] Drugs are not only harmful to people themselves, but also the sewage generated during the preparation of drugs will pollute the environment and destroy the ecological balance. When treating sewage, it is necessary to detect the sewage. At present, when detecting drugs in sewage, it is necessary to extract the drugs in the sewage, and the extraction process is: impurity filtration, mixing auxiliary reagents, passing through the filter column (so that the drug components are adsorbed by the filter column), reagent elution filter column (re-eluting the drug components for easy collection), and collection. When passing through the filter column and reagent elution filter column, traditional detection devices are difficult to automatically replace the filter column, which reduces the detection efficiency, and sewage may leak when the reagent is eluted from the filter column, causing equipment failure, pollution and damage to human health. Summary of the invention

[0003] Other features and advantages of the present invention will be described in the following description, and partly become apparent from the description, or be understood by practicing the present invention. The purpose and other advantages of the present invention can be realized and obtained by the structures specifically pointed out in the description, claims and other drawings of the description.

[0004] The purpose of the present invention is to overcome the above-mentioned shortcomings and provide an automatic column removal and sealing device for online drug analysis equipment.

[0005] To achieve the above purpose, the technical solution of the present invention is:

[0006] An automatic column extraction and sealing device for online drug analysis equipment comprises a bottom plate, a vertical plate, an retrieval device, a column pushing device, a column changing device, and a column pressing device, wherein the vertical plate is arranged on the bottom plate; the retrieval device is arranged on the upper part of the vertical plate; the retrieval device comprises a filter column box, wherein a plurality of filter columns are arranged in the filter column box, a column extraction slide is arranged on the outer side of the filter column box, a baffle rod is arranged on the column extraction slide, and the column extraction slide is used to control the movement of the baffle rod, a column drop bucket is arranged below the filter column box, a groove is provided in the column drop bucket; the column pushing device is arranged below the column drop bucket, the column pushing device comprises a support seat, a column pushing motor, a slider, and a sensor assembly, the column pushing motor and the slider are arranged on the support seat, the slider is connected to the column pushing motor, and the sensor assembly The component is used to sense the signal that the filter column is in place and control the push column motor to make corresponding actions; the column changing device includes a turntable, a turntable motor seat, and a limit assembly. The outer ring of the turntable is provided with a plurality of notches. The turntable motor seat is installed on the bottom plate. The turntable is rotatably connected with the turntable motor seat. The limit assembly is used to sense the turntable position and control the rotation of the turntable motor seat; the pressure column device is arranged above the column changing device. The pressure column device includes a pressure column slide and a pressure column lock seat. The pressure column lock seat is arranged on the pressure column slide, and the pressure column slide is used to control the movement of the pressure column lock seat. The upper end of the pressure column lock seat is provided with a liquid inlet, and the lower end of the pressure column lock seat is provided with a sealing column, and a sealing ring is sleeved on the sealing column. A release limit baffle is installed between the column changing device and the pressure column device.

[0007] Preferably, the column-taking slide comprises a first motor and a first screw rod, the first screw rod is embedded and installed on the first motor, the first screw rod is threadedly connected to the blocking rod, and first limit switches are provided on both sides of the column-taking slide.

[0008] Preferably, the pressure column slide includes a second motor and a second screw rod, the second screw rod is embedded in the second motor, the second screw rod is threadedly connected to the pressure column lock seat, a second limit switch is provided on the pressure column slide, the second limit switch is distributed at the upper and lower ends of the pressure column slide, a pressure column slide fixing frame is installed on the upper part of the vertical plate, and the pressure column slide is installed on the pressure column slide fixing frame.

[0009] Preferably, the support seat includes a push column motor fixing seat and a slider seat, the push column motor is installed on the push column motor fixing seat, and the slider is slidably connected to the slider seat.

[0010] Preferably, the sensor assembly includes a falling column sensor and a pushing column sensor, the falling column sensor is mounted on a pushing column motor fixing seat, a fixing frame is provided on the slider seat, and the pushing column sensor is installed on both sides of the fixing frame.

[0011] Preferably, the limit assembly includes a third limit switch and a limit switch trigger clip, the third limit switch is arranged on both sides of the turntable motor seat, and the limit switch trigger clip is installed at the lower end of the turntable.

[0012] Preferably, a turntable guard plate is provided on one side of the turntable, and a column-losing baffle is provided on the other side of the turntable.

[0013] Preferably, a push column baffle is installed between the turntable motor seat and the vertical plate.

[0014] Preferably, a column drop baffle is installed at the bottom end of the filter column box.

[0015] Preferably, a pressure column baffle is installed on the outer side of the turntable motor base.

[0016] By adopting the above technical solution, the beneficial effects of the present invention are:

[0017] 1. The present invention provides a storage and retrieval device, a column pushing device, a column changing device, and a column pressing device. A limit assembly and a sensor assembly are installed in the four devices, so that the device can realize automatic functions when operating. The coordinated use of the four devices can realize the function of automatically replacing the filter column of the drug detection device, thereby greatly improving the efficiency of online drug analysis and detection.

[0018] 2. The present invention optimizes the setting of the pressure column device, sets a sealing ring and a sealing column to ensure that sewage will not flow out when it flows between the pressure column device and the filter column, thereby improving the safety of the equipment, ensuring the normal operation of the equipment, and avoiding pollution and harm to human health.

[0019] 3. The present invention is optimally provided with a column-dropping baffle to prevent the filter column from falling out when it falls into the column-dropping bucket; the column-pushing baffle is optimally provided to ensure that the filter column can completely enter the turntable slot when the column is pushed; the turntable guard plate is optimally provided to prevent the filter column from being thrown out during transportation to the bottom of the column-pressing device; the column-losing baffle is optimally provided to prevent the used filter column from affecting the operation of the equipment when it is thrown away; the column-pressing baffle is optimally provided to prevent the column-pressing device from warping when pressing the filter column; the release limit baffle is optimally provided to ensure that when the sealing column releases the filter column, the sealing ring and the filter column are completely separated.

[0020] It is to be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present disclosure.

[0021] Undoubtedly, these and other objects of the present invention will become more apparent after the following detailed description of the preferred embodiment described with reference to various figures and drawings.

[0022] In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, one or several preferred embodiments are given below and described in detail with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation of the present invention.

[0024] In the drawings, the same reference numerals are used for the same components and the drawings are schematic and not necessarily drawn to scale.

[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only one or several embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on such drawings without paying creative work.

[0026] Figure 1 It is a rear perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention;

[0027] Figure 2 It is a front perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention;

[0028] Figure 3 It is a schematic diagram of the structure of the storage and retrieval device in the automatic column taking and sealing device of the online drug analysis equipment of the present invention;

[0029] Figure 4 It is a schematic structural diagram of a column pushing device in an automatic column taking and sealing device for online drug analysis equipment according to the present invention;

[0030] Figure 5 It is a schematic structural diagram of a column changing device in an automatic column taking and sealing device for online drug analysis equipment according to the present invention;

[0031] Figure 6 It is a schematic diagram of the structure of the column pressing device in the automatic column taking and sealing device used in the online drug analysis equipment of the present invention;

[0032] Figure 7 It is a schematic diagram of the coordination structure of the column pushing device, column changing device and column pressing device in the automatic column taking and sealing device for online drug analysis equipment of the present invention;

[0033] Figure 8 A top view of the column drop bucket in the automatic column removal and sealing device for online drug analysis equipment of the present invention.

[0034] Description of main reference numerals:

[0035] 1. Bottom plate;

[0036] 2. Vertical board;

[0037] 3. Storage and access device;

[0038] 31. Filter column box;

[0039] 32. Filter column;

[0040] 33. Column removal slide;

[0041] 331, first motor; 332, first screw rod; 333, first limit switch;

[0042] 34. Gear lever;

[0043] 35. Falling column baffle;

[0044] 36. Falling column bucket;

[0045] 361, groove;

[0046] 4. Push column device;

[0047] 41. Support seat;

[0048] 411, push column motor fixing seat; 412, slider seat; 413, fixing bracket;

[0049] 42. Push column motor;

[0050] 43. Slider;

[0051] 44. Sensing components;

[0052] 441, push column sensor; 442, drop column sensor;

[0053] 5. Column changing device;

[0054] 51. Turntable;

[0055] 52. Turntable motor seat;

[0056] 53. Limiting assembly;

[0057] 531, limit switch trigger clip; 532, third limit switch;

[0058] 54. Notch;

[0059] 55. Turntable guard plate;

[0060] 56. Pressure column baffle;

[0061] 57. Push column baffle;

[0062] 58. Lost column baffle;

[0063] 59. Release the limit baffle;

[0064] 6. Column pressing device;

[0065] 61. Press column slide;

[0066] 611, second motor; 612, second screw rod; 613, second limit switch;

[0067] 62. Press column lock seat;

[0068] 621, sealing column; 622, sealing ring; 623, liquid inlet;

[0069] 63. Pressure column slide fixing bracket. DETAILED DESCRIPTION

[0070] The following will describe the implementation methods of the present invention in detail with reference to the accompanying drawings and embodiments, so that the implementation process of how the present invention applies technical means to solve technical problems and achieve technical effects can be fully understood and implemented accordingly. It should be noted that as long as there is no conflict, the various embodiments of the present invention and the various features in the embodiments can be combined with each other, and the technical solutions formed are all within the protection scope of the present invention.

[0071] Meanwhile, in the following description, many specific details are set forth for the purpose of explanation to provide a thorough understanding of the embodiments of the present invention. However, it is obvious to those skilled in the art that the present invention can be implemented without the specific details or the specific manner described herein.

[0072] Reference Figure 1-3 and Figure 7-8 , Figure 1 It is a rear perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 2 It is a front perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 3 It is a schematic diagram of the structure of the storage and retrieval device in the automatic column taking and sealing device of the online drug analysis equipment of the present invention; Figure 7 It is a schematic diagram of the coordination structure of the column pushing device, column changing device and column pressing device in the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 8 A top view of the column drop bucket in the automatic column removal and sealing device for online drug analysis equipment of the present invention.

[0073] The present embodiment provides an automatic column extraction and sealing device for online drug analysis equipment, including a bottom plate 1, a vertical plate 2, an access device 3, a column pushing device 4, a column changing device 5, and a column pressing device 6. The vertical plate 2 is arranged on the bottom plate 1; the access device 3 is arranged on the upper part of the vertical plate 2, and the access device 3 includes a filter column box 31, and a plurality of filter columns 32 are arranged in the filter column box 31. The filter columns 32 can be increased according to the needs of the user. A column extraction slide 33 is arranged on the outside of the filter column box 31, and the column extraction slide 33 is connected to a blocking rod 34, and the column extraction slide 33 is used to control the movement of the blocking rod 34, and the blocking rod 34 is released by moving left and right. A filter column 32, a column drop bucket 36 is provided at the bottom of the filter column box 31, and a groove 361 is opened in the column drop bucket 36. After the filter column 32 is released, it falls into the column drop bucket 36. A column drop baffle 35 is installed at the bottom end of the filter column box 31 to prevent the filter column 32 from falling out when it falls into the column drop bucket 36. The column removal slide 33 includes a first motor 331 and a first screw rod 332. The first screw rod 332 is embedded and installed on the first motor 331 to realize transmission connection. The first screw rod 332 is threadedly connected to the baffle rod 34. First limit switches 333 are provided on both sides of the column removal slide 33, and the motor screw principle is adopted to control the left and right movement of the baffle rod.

[0074] Reference Figure 1 , Figure 4 and Figure 7 , Figure 1 It is a rear perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 4 It is a schematic structural diagram of a column pushing device in an automatic column taking and sealing device for online drug analysis equipment according to the present invention; Figure 7 The present invention is a schematic diagram of the coordination structure of the column pushing device, the column changing device and the column pressing device in the automatic column taking and sealing device for online drug analysis equipment.

[0075] The push column device 4 is arranged below the column bucket 36, and the push column device 4 includes a support seat 41, a push column motor 42, a slider 43, and a sensor assembly 44. The push column motor 42 and the slider 43 are arranged on the support seat 41, and the slider 43 is connected to the push column motor 42. The push column motor 42 is used to push the slider 43. The sensor assembly 44 is used to sense the signal that the filter column 32 is in place and control the push column motor 42 to push. The support seat 41 includes a push column motor fixing seat 411 and a slider seat 412. The push column motor 42 is installed on the push column motor fixing seat 41. 1, the slider 43 is slidably connected to the slider seat 412, the sensor assembly 44 includes a column drop sensor 442 and a column push sensor 441, the column drop sensor 442 is installed on the column push motor fixing seat 411, the slider seat 412 is provided with a fixing frame 413, the column push sensor 441 is installed on both sides of the fixing frame 413, the column drop sensor 442 is used to detect whether the filter column 32 falls into the column drop bucket 36, and the column push sensor 441 is used to detect whether the slider 43 is pushed into place, and control the column push motor 42 to make corresponding actions.

[0076] Reference Figure 2 , Figure 5 and Figure 7 , Figure 2 It is a front perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 5 It is a schematic structural diagram of a column changing device in an automatic column taking and sealing device for online drug analysis equipment according to the present invention; Figure 7 The present invention is a schematic diagram of the coordination structure of the column pushing device, the column changing device and the column pressing device in the automatic column taking and sealing device for online drug analysis equipment.

[0077] The column changing device 5 includes a turntable 51, a turntable motor seat 52, and a limit assembly 53. The outer ring of the turntable 51 is provided with a plurality of notches 54, and the notches 54 are used to receive the filter column 32 pushed by the push column device 4. The turntable motor seat 52 is installed on the bottom plate 1 and is arranged on a plate opposite to the push column device. The turntable 51 is rotatably connected to the turntable motor seat 52. The limit assembly 53 is used for sensing the position of the turntable 51 and controlling the operation of the turntable motor seat 52 to control the turntable 51 to switch between the push column device 4 position and the pressure column device 6 position. The limit assembly 53 includes a third limit switch 532 and a limit switch trigger clip 531. The third limit switch 532 is arranged on both sides of the turntable motor seat 52, and the two sides are the push column devices. 4 position and the position of the column pressing device 6, the limit switch trigger clip 531 is installed at the lower end of the turntable 51, and cooperates with the third limit switch 532 to switch the turntable 51 between the column pushing device 4 position and the column pressing device 6 position; a turntable guard plate 55 is provided on one side of the turntable 51 to prevent the filter column 32 from being thrown out during the transportation to the bottom of the column pressing device 6, and a column throwing baffle 58 is provided on the other side of the turntable to prevent the used filter column 32 from being thrown away and affecting the operation of the equipment; a column pushing baffle 57 is installed between the turntable motor seat 52 and the vertical plate 2 to ensure that the filter column 32 can fully enter the turntable slot 54 when pushing the column, and a column pressing baffle 56 is installed on the outside of the turntable motor seat 52 to prevent the column pressing device 6 from warping when pressing into the filter column 32.

[0078] Reference Figure 2 , Figure 6 and Figure 7 , Figure 2 It is a front perspective structural schematic diagram of the automatic column taking and sealing device for online drug analysis equipment of the present invention; Figure 6 It is a schematic diagram of the structure of the column pressing device in the automatic column taking and sealing device used in the online drug analysis equipment of the present invention; Figure 7 The present invention is a schematic diagram of the coordination structure of the column pushing device, the column changing device and the column pressing device in the automatic column taking and sealing device for online drug analysis equipment.

[0079] The column pressing device 6 is arranged above the column changing device 5, and the column pressing device 6 includes a column pressing slide 61 and a column pressing lock seat 62. The column pressing lock seat 62 is connected to the column pressing slide 61, and the column pressing slide 61 is used to control the movement of the column pressing lock seat 62. The upper end of the column pressing lock seat 62 is provided with a liquid inlet 623, and sewage flows in from the liquid inlet 623. The lower end of the column pressing lock seat 62 is provided with a sealing column 621, and a sealing ring 622 is sleeved on the sealing column 621. A release limit baffle 59 is installed between the column changing device 5 and the column pressing device 6 to ensure that when the sealing column 621 releases the filter column 32, the sealing ring 622 and the filter column 32 are completely Fully disengaged, the pressure column slide 61 includes a second motor 611 and a second screw rod 612. The second screw rod 612 is embedded and installed on the second motor 611 to realize transmission connection. The second screw rod 612 is threadedly connected to the pressure column lock seat 62. The pressure column slide 61 is provided with a second limit switch 613. The second limit switch 613 is distributed at the upper and lower ends of the pressure column slide 61. The motor screw principle is used to control the up and down movement of the pressure column lock seat 62. A pressure column slide fixing frame 63 is installed on the upper part of the vertical plate 2. The pressure column slide 61 is installed on the pressure column slide fixing frame 63 and is arranged on the vertical plate 2 opposite to the access device 3.

[0080] When the automatic column taking and sealing device for online drug analysis equipment is used, the filter column 32 is placed in the filter column box 31, the filter columns 32 are placed alternately, and the column taking slide 33 controls the lever to move left and right to control the release of the filter column 32. A column drop baffle 35 is provided at the lower end of the filter column box 31 to prevent the filter column 32 from falling into the column drop bucket 36 and falling out. After the filter column 32 is released, it falls into the column drop bucket 36. After the column drop sensor 442 detects the filter column 32, it controls the column push motor 42 to push the slider 43. A column push baffle 57 is installed between the turntable motor seat 52 and the vertical plate 2 to ensure that the filter column is filtered when pushed. The column 32 can completely enter the slot 54 of the turntable 51. After the slider 43 pushes the filter column 32 from the slot 361 in the column bucket 36 into the slot 54 of the turntable 51, the push column sensor 441 detects that the slider 43 is in place (that is, the filter column 32 is pushed into place) and then controls the push column motor 42 to slide the slider 43 to the initial position. After the filter column 32 is in place, the limit switch trigger clamp 531 cooperates with the third limit switch 532 to control the rotation of the turntable motor seat 52. The turntable 51 is installed with a turntable guard plate 55 on the path of transporting the filter column 32 to the column pressing device 6 to prevent the turntable 51 from rotating at high speed during transportation. When the filter column 32 is transported to the position of the pressure column device 6, the pressure column lock seat 62 slides downward, and the sealing column 621 is pressed into the filter column 32. The sealing ring 622 set on the sealing column 621 plays a sealing role to prevent sewage from leaking. A pressure column baffle 56 is installed on the outside of the turntable motor seat 52 (that is, between the filter column 32 in place and the turntable motor seat 52) ​​to prevent the filter column 32 from bending and affecting the test when pressed down. After the pressing is completed, the sewage pipe is connected to the liquid inlet 623, and the sewage then enters the filter column 32. The speed of the liquid passing through the column is achieved by adjusting the liquid delivery speed of the control pump. The speed at which the liquid passes through the column will affect the test effect. A waste liquid bucket is set under the filter column 32 to collect the waste liquid. The drugs in the sewage are adsorbed by the filter column 32 when passing through the column. A waste liquid bucket is set under the filter column 32 to collect the waste liquid. After the adsorption is completed, the sewage pipe is pulled out and the reagent pipe is connected from the liquid inlet 623. The reagent elutes the drugs, and then the eluent is collected. When replacing the next filter column 32, the rotation of the turntable 51 will throw out the used filter column 32. A column loss baffle 58 is installed on one side of the turntable for throwing out the filter column 32 to prevent the used filter column 32 from affecting the operation of the equipment when it is thrown away.

[0081] It should be understood that the embodiments disclosed in the present invention are not limited to the specific processing steps or materials disclosed herein, but should be extended to equivalent substitutions of such features understood by ordinary technicians in the relevant field. It should also be understood that the terms used herein are only used for the purpose of describing specific embodiments and are not meant to be limiting.

[0082] The "embodiment" mentioned in the specification means that the specific features or characteristics described in conjunction with the embodiment are included in at least one embodiment of the present invention. Therefore, the phrases or "embodiment" appearing in various places throughout the specification do not necessarily refer to the same embodiment.

[0083] In addition, the described features or characteristics may be combined in one or more embodiments in any other suitable manner. In the above description, some specific details, such as thickness, quantity, etc., are provided to provide a comprehensive understanding of the embodiments of the present invention. However, those skilled in the relevant art will understand that the present invention can be implemented without one or more of the above specific details or can also be implemented using other methods, components, materials, etc.

Claims

1. An automatic column extraction and sealing device for online drug analysis equipment, characterized in that: include Base plate; A vertical plate, which is arranged on the bottom plate; A storage and retrieval device is arranged on the upper part of the vertical plate, the storage and retrieval device includes a filter column box, a plurality of filter columns are arranged in the filter column box, a column retrieval slide is arranged on the outside of the filter column box, the column retrieval slide includes a first motor and a first screw rod, the first screw rod is embedded and installed on the first motor, the first screw rod is threadedly connected with the blocking rod, first limit switches are arranged on both sides of the column retrieval slide, a blocking rod is arranged on the column retrieval slide, and the column retrieval slide is used to control the movement of the blocking rod, a column drop bucket is arranged below the filter column box, and a groove is opened in the column drop bucket; A column pushing device is arranged below the column drop bucket, and includes a support seat, a column pushing motor, a slider, and a sensor assembly. The column pushing motor and the slider are arranged on the support seat, and the slider is connected to the column pushing motor. The sensor assembly is used to sense the filter column in place signal and control the column pushing motor to make corresponding actions; The column changing device comprises a turntable, a turntable motor seat, and a limit assembly. The outer ring of the turntable is provided with a plurality of notches. The turntable motor seat is mounted on a bottom plate. The turntable is rotatably connected to the turntable motor seat. The limit assembly is used for turntable position sensing and controlling the rotation of the turntable motor seat. A pressure column device is arranged above the column changing device, the pressure column device includes a pressure column slide and a pressure column lock seat, the pressure column slide includes a second motor and a second screw rod, the second screw rod is embedded and installed on the second motor, the second screw rod is threadedly connected to the pressure column lock seat, a second limit switch is provided on the pressure column slide, and the second limit switch is distributed at the upper end and the lower end of the pressure column slide, a pressure column slide fixing frame is installed on the upper part of the vertical plate, the pressure column slide is installed on the pressure column slide fixing frame, the pressure column lock seat is arranged on the pressure column slide, and the pressure column slide is used to control the movement of the pressure column lock seat, a liquid inlet is provided at the upper end of the pressure column lock seat, a sealing column is provided at the lower end of the pressure column lock seat, a sealing ring is sleeved on the sealing column, and a release limit baffle is installed between the column changing device and the pressure column device.

2. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: The support seat comprises a push column motor fixing seat and a slider seat. The push column motor is installed on the push column motor fixing seat, and the slider is slidably connected to the slider seat.

3. The automatic column extraction and sealing device for online drug analysis equipment according to claim 2 is characterized in that: The sensor assembly comprises a column drop sensor and a column push sensor. The column drop sensor is mounted on a column push motor fixing seat. A fixing frame is arranged on the slider seat. The column push sensor is mounted on both sides of the fixing frame.

4. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: The limit assembly comprises a third limit switch and a limit switch triggering clip. The third limit switch is arranged on both sides of the turntable motor seat, and the limit switch triggering clip is installed at the lower end of the turntable.

5. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: A turntable guard plate is arranged on one side of the turntable, and a column-losing baffle is arranged on the other side of the turntable.

6. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: A push column baffle is installed between the turntable motor seat and the vertical plate.

7. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: A column drop baffle is installed at the bottom end of the filter column box.

8. The automatic column extraction and sealing device for online drug analysis equipment according to claim 1 is characterized in that: A pressure column baffle is installed on the outer side of the turntable motor seat.

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