Application of calcium beta-hydroxy-beta-methylbutyrate in improving production performance of horses

By feeding β-hydroxy-β-methylbutyrate after horse foal production, the problems of low horse milk production and poor mare production performance were solved, which significantly improved milk production and improved the metabolic function of mare.

CN119563768APending Publication Date: 2025-03-07XINJIANG AGRI UNIV
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Patent Information

Application Number
CN202510074385.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-16
Publication Date
2025-03-07

AI Technical Summary

Technical Problem

The low yield of horse milk and insufficient energy and nutrition during the lactation period leads to poor mare production performance and cannot fully meet the growth and development and nutritional needs of foals.

Method used

Increase the milk production of mares by feeding β-hydroxy-β-methylbutyrate, especially one to three months after the mare has a foal. After mixing β-hydroxy-β-methylbutyrate with the concentrate, the feeding amount is 10-50g/day/pi.

Benefits of technology

It significantly increased the milk production of mares, improved the metabolic function of mares, reduced blood sugar, total bilirubin and triglyceride content, and increased the total protein content.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The invention provides an application of calcium beta-hydroxy-beta-methylbutyrate in improving the production performance of horses, and belongs to the technical field of animal breeding. Research finds that the milk yield of mare can be remarkably increased through supplementary feeding of the calcium beta-hydroxy-beta-methylbutyrate, but milk components are not remarkably influenced; the content of urea in plasma can be reduced on the 30th day after the calcium beta-hydroxy-beta-methylbutyrate is fed, and the content of blood sugar, the content of total bilirubin and the content of triglyceride can be remarkably reduced on the 60th day, and the content of total protein can be increased. And the calcium beta-hydroxy-beta-methylbutyrate can effectively improve the production performance of the mare.
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Description

Technical Field

[0001] The invention belongs to the technical field of animal breeding, and in particular relates to application of calcium beta-hydroxy-beta-methylbutyrate in improving the production performance of horses. Background Art

[0002] The yield and quality of mare's milk are not only important factors in determining the normal growth and development of offspring, but also have important economic value because its nutritional components are similar to human milk and easy to absorb. However, the yield of mare's milk is low and there is a problem of competition between humans and animals for food during the lactation period, which means that the mare's milk produced cannot fully meet the growth and development and nutritional needs of foals and market needs. Secondly, during lactation, mares will use a lot of energy and nutritional substrates to meet the needs of milk component synthesis, and grazing alone cannot guarantee the full performance of mare's production performance. Increasing the amount of milk produced by mares or improving the quality of milk components through energy supplementation during lactation is of great significance to promoting the healthy growth and development of foals and the performance of mare's production performance.

[0003] Calcium β-hydroxy-β-methylbutyrate is a metabolite of branched-chain amino acids and plays an important role in the protein synthesis of muscle tissue. As a new type of anabolic nutrient for high-intensity athletes, calcium β-hydroxy-β-methylbutyrate can reduce body fat and reduce muscle protein consumption. Calcium β-hydroxy-β-methylbutyrate is also a strong immune stimulant that can enhance the body's immune function. In recent years, more and more studies have shown that calcium β-hydroxy-β-methylbutyrate also has multiple biological functions such as lowering blood lipids, improving inflammation, regulating cell proliferation, and affecting intestinal microbial composition. At present, there are no reports on whether supplementation with β-hydroxy-β-methylbutyrate and its calcium salt can have a positive effect on horse milk production. Summary of the invention

[0004] In view of this, the object of the present invention is to provide an application of calcium β-hydroxy-β-methylbutyrate in improving the production performance of horses. The milk production of mares can be significantly increased by supplementing calcium β-hydroxy-β-methylbutyrate.

[0005] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0006] The use of calcium β-hydroxy-β-methylbutyrate in improving horse production performance.

[0007] Preferably, improving the production performance of the horse includes increasing the milk production of the horse.

[0008] Another object of the present invention is to provide a method for increasing milk production of horses, comprising the following steps: supplementing the mare with calcium β-hydroxy-β-methylbutyrate after giving birth.

[0009] Preferably, the period after foaling is 1 to 3 months after foaling.

[0010] Preferably, the supplementary feeding amount of calcium β-hydroxy-β-methylbutyrate is 10 to 50 g / d / horse.

[0011] Preferably, the mare is ≥ 3.5 years old.

[0012] Preferably, the mass of the mare is 350-500 kg / horse.

[0013] Preferably, calcium β-hydroxy-β-methylbutyrate is mixed with concentrate and then fed to the mares.

[0014] Preferably, the horse breeds include Ili horses, Kazakh horses, Yanqi horses or Kirgiz horses.

[0015] Another object of the present invention is to provide an additive for improving the production performance of horses, wherein the additive contains calcium β-hydroxy-β-methylbutyrate.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The present invention provides an application of calcium β-hydroxy-β-methylbutyrate in improving the production performance of horses. The present invention has found that supplementing calcium β-hydroxy-β-methylbutyrate can significantly increase the milk production of mares, but has no significant effect on milk components; supplementing calcium β-hydroxy-β-methylbutyrate can reduce plasma urea content on the 30th day, and significantly reduce blood sugar content, total bilirubin content and triglyceride content on the 60th day, and increase total protein content. Calcium β-hydroxy-β-methylbutyrate can effectively improve the production performance of horses. DETAILED DESCRIPTION

[0018] The invention provides application of calcium beta-hydroxy-beta-methylbutyrate in improving production performance of horses, wherein improving production performance of horses comprises improving milk production of horses.

[0019] The present invention also provides a method for increasing the milk production of horses, comprising the following steps: supplementing the mare with calcium beta-hydroxy-beta-methylbutyrate after the mare gives birth.

[0020] In the method for increasing the milk production of horses of the present invention, the concentrate supplement is mixed with calcium β-hydroxy-β-methylbutyrate and placed in a feed bag for supplementary feeding; the post-foaling period is the first to third months after the foaling; the supplementary feeding amount of calcium β-hydroxy-β-methylbutyrate is 10 to 50 g / d / horse, preferably 15 to 30 g / d / horse, and more preferably 20 g / d / horse; the age of the mare is ≥3.5 years old; the weight of the mare is 350 to 500 kg / horse. The present invention supplements calcium β-hydroxy-β-methylbutyrate when the mare is in the lactation period after the foaling, which can effectively increase the milk production of the mare. At the same time, supplementary feeding of calcium β-hydroxy-β-methylbutyrate can also increase the total protein content, reduce blood sugar, total bilirubin and triglyceride content, and improve the metabolic function of the mare.

[0021] In the present invention, the horse breeds include Ili horse, Kazakh horse, Yanqi horse or Kirgiz horse, preferably Ili horse.

[0022] The present invention also provides an additive for improving the production performance of horses, wherein the additive contains calcium β-hydroxy-β-methylbutyrate. The additive provided by the present invention can be added to the daily feed of horses, and the production performance of horses can be effectively improved by feeding the horses.

[0023] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0024] Example 1

[0025] A method for increasing milk production in horses, comprising the following steps:

[0026] For mares aged 5 to 7 years old, with a body weight between 350 and 500 kg / horse, they should be fed with calcium β-hydroxy-β-methylbutyrate in the first to third months after giving birth. The concentrate supplement should be mixed with calcium β-hydroxy-β-methylbutyrate and placed in a feed bag for supplementary feeding. The supplementary feeding amount is 10g / d / horse.

[0027] Example 2

[0028] A method for increasing milk production in horses, comprising the following steps:

[0029] For mares aged 5 to 7 years old, with a body weight between 350 and 500 kg / horse, they should be fed with calcium β-hydroxy-β-methylbutyrate in the first to third months after giving birth. The concentrate supplement should be mixed with calcium β-hydroxy-β-methylbutyrate and placed in a feed bag for supplementary feeding. The supplementary feeding amount is 20 g / d / horse.

[0030] Example 3

[0031] A method for increasing milk production in horses, comprising the following steps:

[0032] For mares aged 5 to 7 years old, with a body weight between 350 and 500 kg / horse, they should be fed with calcium β-hydroxy-β-methylbutyrate in the first to third months after foaling. The concentrate supplement should be mixed with calcium β-hydroxy-β-methylbutyrate and placed in a feed bag for supplementary feeding. The supplementary feeding amount is 30 g / d / horse.

[0033] Example 4

[0034] Effect of supplemental feeding with calcium β-hydroxy-β-methylbutyrate.

[0035] 1. Experimental animals and experimental design.

[0036] The experiment selected 18 Ili horses aged 5-7 years and with 2-4 parities, and randomly divided them into 3 groups according to the average milk production, namely the control group, test group I and test group II (N=6). The control group, test group I and test group II were supplemented with 500g / d / horse of concentrate supplement, and test group I and test group II were supplemented with 10g / d / horse of β-hydroxy-β-methylbutyrate calcium (Example 1) and 20g / d / horse of β-hydroxy-β-methylbutyrate calcium (Example 2) on the basis of supplementing the concentrate supplement. The roughage fed to the experimental horses was green hay, and the nutritional level of the concentrate supplement was shown in Table 1.

[0037] Table 1 Nutritional level of concentrate supplementary feed

[0038] Nutritional Levels content(%) Dry matter 90.09 Organic matter 83.19 Crude Protein 17.45 Crude fat 2.99 Crude Fiber 3.27 Coarse ash 6.90

[0039] 2. Feeding and management.

[0040] All mares were milked for 10 hours during the day, and milk production was recorded every two hours. During this period, the foals were separated from the mares and did not eat breast milk. The foals were grazed together with the mares for the remaining 14 hours. At 10:00 a.m. every day, the mares and foals were driven from the grazing pasture to the sty for tethering. The mares in the experimental group were fed with corresponding levels of calcium β-hydroxy-β-methylbutyrate using a feed bag. At the same time, the mares and foals were separated during the milking time. At 20:00 p.m., when the last milking was over, the mares and foals were grouped together and driven back to the grazing pasture together. During the milking period, the mares were free to eat green hay and drink water.

[0041] 3. Results

[0042] 3.1 Effect of supplemental feeding of calcium β-hydroxy-β-methylbutyrate on milk production in mares

[0043] The effect of supplementing calcium β-hydroxy-β-methylbutyrate on milk production in horses is shown in Table 2. In the method provided by the present invention, supplementing calcium β-hydroxy-β-methylbutyrate from day 1 to day 15, the milk production of test group II was significantly higher than that of the control group, from day 16 to day 30, the milk production of test group I was significantly higher than that of the control group, and the milk production of test group II was significantly higher than that of the control group, and from day 31 to day 45 and from day 46 to day 60, the milk production of test group I and test group II was significantly higher than that of the control group. The test results show that supplementing calcium β-hydroxy-β-methylbutyrate can significantly increase the milk production of mares.

[0044] Table 2 Effect of supplementary feeding of calcium β-hydroxy-β-methylbutyrate on milk production in mares

[0045]

[0046] Note: Data in the same row without letters or with the same letters indicate no significant difference (P>0.05), different capital letters indicate extremely significant difference (P<0.01), and different lowercase letters indicate significant difference (P<0.05).

[0047] 3.2 Effect of supplementing calcium β-hydroxy-β-methylbutyrate on the composition of mare milk.

[0048] The effect of supplementing calcium β-hydroxy-β-methylbutyrate on the composition of mare milk is shown in Table 3. As shown in Table 3, there was no significant difference in milk composition between the control group, test I and test II groups at day 0, day 30 and day 60.

[0049] Table 3 Effect of supplementing calcium β-hydroxy-β-methylbutyrate on mare milk composition

[0050]

[0051] Note: Data in the same row without letters or with the same letters indicate no significant difference (P>0.05), different capital letters indicate extremely significant difference (P<0.01), and different lowercase letters indicate significant difference (P<0.05).

[0052] 3.3 Effect of supplementing calcium β-hydroxy-β-methylbutyrate on blood biochemical parameters of horses.

[0053] The effects of supplementing with calcium β-hydroxy-β-methylbutyrate on blood biochemical indices of horses are shown in Table 4. On the 30th day after supplementing with calcium β-hydroxy-β-methylbutyrate, the total protein in the control group was significantly higher than that in the experimental group II. On the 60th day, the urea content in the experimental groups I and II was significantly higher than that in the control group; the blood glucose content, total bilirubin content, and triglyceride content were significantly lower than those in the control group; the total protein content in the experimental group I was significantly higher than that in the control group; and there were no significant differences in the other indices. It can be seen that supplementing with calcium β-hydroxy-β-methylbutyrate improved the metabolic function of mares.

[0054] Table 4 Effects of supplementary feeding of calcium β-hydroxy-β-methylbutyrate on blood biochemical parameters of horses

[0055]

[0056] Note: Data in the same row without letters or with the same letters indicate no significant difference (P>0.05), different capital letters indicate extremely significant difference (P<0.01), and different lowercase letters indicate significant difference (P<0.05).

[0057] In summary, supplementing with calcium β-hydroxy-β-methylbutyrate significantly increased the milk production of mares, but had no significant effect on milk composition; supplementing with calcium β-hydroxy-β-methylbutyrate could reduce plasma urea content on the 30th day, and significantly reduce blood glucose content, total bilirubin content and triglyceride content on the 60th day, and increase total protein content.

[0058] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. Application of calcium β-hydroxy-β-methylbutyrate in improving the production performance of horses.

2. The use according to claim 1, characterized in that: The improving the production performance of the horse includes improving the milk production of the horse.

3. A method for increasing milk production in horses, characterized in that: The method comprises the following steps: supplementing beta-hydroxy-beta-methylbutyrate calcium to the mare after the mare gives birth.

4. The method according to claim 3, characterized in that The post-foaling period refers to the 1st to 3rd month after the foaling period.

5. The method according to claim 3, characterized in that: The supplementary feeding amount of β-hydroxy-β-methylbutyrate calcium is 10-50g / d / horse.

6. The method according to claim 3, characterized in that The mare is ≥ 3.5 years old.

7. The method according to claim 3, characterized in that The mass of the mare is 350-500 kg / horse.

8. The method according to claim 3, characterized in that Calcium β-hydroxy-β-methylbutyrate is mixed with concentrate and fed to mares.

9. The use according to claim 1 or the method according to claim 3, characterized in that: The horse breeds include Ili horses, Kazakh horses, Yanqi horses or Kirgiz horses.

10. An additive for improving the production performance of horses, characterized in that: The additive contains calcium β-hydroxy-β-methylbutyrate.