Automatic blood sample testing device

By combining the magnetic separation assembly and the mixing assembly in the blood sample automatic testing device, the problem of long execution cycle of mixing operation in the prior art is solved, and the sufficient mixing of the reaction liquid and the accuracy of the test results are improved.

CN119643848AActive Publication Date: 2025-03-18NINGBO AUCHEER BIOTECHNOLOGY CO LTD

Patent Information

Application Number
CN202510188625.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-02-20
Publication Date
2025-03-18
Estimated Expiration
2045-02-20

AI Technical Summary

Technical Problem

In the existing automatic blood sample testing device, the mixing operation of the mixing mechanism is performed for a long time, resulting in insufficient mixing of the reaction liquid, which affects the accuracy of the test results.

Method used

A blood sample automatic testing device is designed, using a structure that combines a magnetic separation assembly and a mixing assembly. The magnetic particles in the reaction cup are adsorbed and cleaned by the magnetic separation assembly, and the reaction cup is shaken by the mixing assembly to achieve sufficient mixing of the reaction liquid.

Benefits of technology

The mixing cycle and reaction time of the liquid in the reaction cup are shortened, and the accuracy of the test results is improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses an automatic blood sample testing device, and relates to the technical field of blood sample detection, the automatic blood sample testing device comprises a fixing frame, a magnetic suction separation assembly is arranged on the fixing frame, a reaction cup is placed on the magnetic suction separation assembly, and a waste liquid discharge assembly located above the magnetic suction separation assembly is arranged on the fixing frame. The waste liquid discharging assembly corresponds to a reaction cup placed on the magnetic suction separation assembly, the fixing frame is provided with uniform mixing assemblies located on the two sides of the magnetic suction separation assembly, and the uniform mixing assemblies make contact with the bottom of the reaction cup. Magnetic particles combined with antigens in a blood sample in the reaction cup are adsorbed through the magnetic attraction separation assembly, cleaning liquid is added into the reaction cup for cleaning, waste liquid obtained after cleaning in the reaction cup is discharged through the waste liquid discharging assembly, then acid is added into the reaction cup for reaction, and the uniform mixing assembly makes contact with the bottom of the reaction cup, so that the reaction cup is uniformly mixed. The reaction cup is shaken in time, so that liquid in the reaction cup is uniformly mixed, and the uniform mixing time of the uniform mixing assembly is shortened.
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Description

Technical Field

[0001] The present application relates to the technical field of blood sample detection, and in particular to an automatic blood sample testing device. Background Art

[0002] In chemiluminescent immunoassay, magnetic particle complex is a carrier of the signal to be tested. Magnetic separation technology is to separate the solid-liquid phase of the reaction solution after the magnetic particle complex is mixed with the blood sample and the reaction reagent. In order to ensure the effect of magnetic separation, the reaction solution needs to be fully mixed during the separation process. So as to obtain accurate test results. In the current prior art, contact paddle mixing and suction liquid mixing structures are mainly used. In the automatic detection device, a mixing mechanism and a stirring rod are usually used to stir the solution in a reactor at a time to mix the liquid in the reactor.

[0003] With respect to the above-mentioned related technologies, the inventors believe that the solution in the reactor is mixed by a mixing mechanism and a stirring rod, and the mixing action execution cycle of the mixing mechanism is relatively long. Summary of the invention

[0004] The purpose of the present application is to provide an automatic blood sample testing device to improve the problem that a solution in a reactor is mixed by a mixing mechanism and a stirring rod, and the mixing action execution cycle of the mixing mechanism is relatively long.

[0005] The present application provides an automatic blood sample testing device, which adopts the following technical solution: A blood sample automatic testing device comprises a fixing frame, a magnetic separation component for placing a reaction cup is arranged above the fixing frame, a waste liquid discharge component corresponding to the reaction cup is arranged above the magnetic separation component, and mixing components are arranged on both sides of the fixing frame on the magnetic separation component, and the mixing components are in contact with the bottom of the reaction cup.

[0006] By adopting the above technical scheme, the reaction cup is placed in the magnetic separation component, the magnetic separation component is used to adsorb the magnetic particles combined with the antigen in the blood sample in the reaction cup, a cleaning liquid is added to the reaction cup for cleaning, the waste liquid after cleaning in the reaction cup is discharged through the waste liquid discharge component located above the magnetic separation component, and then acid is added to the reaction cup for reaction, and the mixing components arranged on both sides of the magnetic separation component are in contact with the bottom of the reaction cup, and the reaction cup is shaken to fully mix the liquid in the reaction cup, shorten the mixing cycle of mixing the reaction cup, and shorten the reaction time of the liquid in the reaction cup.

[0007] Optionally, the magnetic separation component includes a fixed seat arranged above the fixed frame, the fixed seat is provided with a fixing hole, a rotating rod is rotatably arranged in the fixing hole, the rotating rod is located above the fixed seat and is fixedly connected to a rotating disk, a driving member 1 is connected to the lower part of the fixed frame and is belt-driven with the rotating rod, a fixing groove 1 corresponding to the reaction cup is provided on the edge of the rotating disk, the fixing groove 1 is in contact with the edge of the reaction cup, and a chamfer is provided on the side of the fixing groove close to the fixed frame.

[0008] By adopting the above technical scheme, a fixing seat is installed on the fixing frame, a fixing hole is provided at the center position of the fixing seat, the rotating rod is rotatably set in the fixing hole, a driving member 1 connected to the rotating rod with a transmission is connected to the fixing frame, the rotating disk and the rotating rod are fixedly connected above the fixing seat, and the rotating rod is driven by the driving member 1 to drive the rotating disk to rotate; a fixing groove 1 is provided on the rotating disk, and a chamfer is provided on one side of the fixing groove 1 close to the fixing seat, so that the reaction cup placed in the fixing groove 1 can be shaken under the action of the mixing component, so as to prevent the reaction cup from being broken due to excessive contact area between the reaction cup and the side wall of the fixing groove 1 when the mixing component shakes the reaction cup.

[0009] Optionally, the fixing frame is connected to a support frame one above the fixing seat, and the support frame one is located on the side of the waste liquid discharge component close to the rotating disk. One end of the support frame one is provided with a cleaning liquid adding hole corresponding to the reaction cup, and the other end of the support frame one is provided with an acid adding hole corresponding to the reaction cup. The acid adding hole, the cleaning liquid adding hole and the mixing component are on the same axis.

[0010] By adopting the above technical scheme, a support frame 1 is connected to the fixed frame, so that the support frame 1 is located above the rotating disk, and the support frame 1 corresponds to the waste liquid discharge component. A cleaning liquid adding hole is set at one end of the support frame 1. The reaction cup rotates with the rotating disk and is located at the same axial position as the cleaning liquid adding hole. Cleaning liquid is added to the reaction cup, and the mixing component on the fixed frame starts to shake the reaction cup to mix the liquid in the reaction cup; an acid adding hole is set at the other end of the support frame 1, acid is added to the reaction cup, and the reaction cup after acid addition is shaken by the mixing component, so that the mixing cycle of the mixing component is shortened, and the liquid in the reaction cup is fully mixed.

[0011] Optionally, a connecting groove is provided on the side wall of the fixing seat, a magnetic member for adsorbing antigens combined with magnetic particles in the reaction cup is connected in the connecting groove, and a groove corresponding to the mixing component is provided on the side wall of the fixing seat.

[0012] By adopting the above technical solution, a magnetic part is installed in the connecting groove opened on the fixed seat. When the reaction cup on the rotating disk rotates with the rotating disk, the magnetic part adsorbs the magnetic particles in the reaction cup that are magnetically connected to the antigens in the blood sample, thereby preventing the waste liquid in the reaction cup from being discharged together with the antigens in the reaction cup when the cleaning liquid is subsequently added to the reaction cup for cleaning, thereby preventing the waste liquid in the reaction cup from being discharged together with the antigens in the reaction cup when the waste liquid discharge component is drawn out, causing errors in subsequent test results.

[0013] Optionally, the waste liquid discharge component includes a waste liquid needle, the fixed frame is connected to a mounting frame extending upward, the mounting frame is slidably connected to a connecting frame, the connecting frame is in contact with a mixing component, a support frame 2 is connected above the connecting frame, the support frame 2 is located above the support frame 1 and is connected to the waste liquid needle, and a driving member 2 is connected below the fixed frame, the driving rod of the driving member 2 is fixedly connected to a screw rod, and the screw rod is rotatably connected to the connecting frame.

[0014] By adopting the above technical scheme, the mounting frame extending upward is connected to the fixed frame, the connecting frame is slidably connected to the mounting frame, the connecting screw is rotated on the connecting frame, the driving member 2 is connected and set on the fixed frame, the driving rod of the driving member 2 is fixedly connected to the screw, and the screw is driven to rotate by the driving member 2, so that the screw pushes the connecting frame to move on the mounting frame, and the connecting frame drives the mixing component to move and contact the bottom of the reaction cup; the supporting frame 2 is connected to the connecting frame, and the waste liquid needle is connected to the supporting frame 2, so that the waste liquid needle moves toward the reaction cup with the movement of the connecting frame, and the waste liquid generated after the cleaning liquid is added to the reaction cup is extracted.

[0015] Optionally, a fixed block is connected to one side of the support frame 1 close to the support frame 2, and the fixed block and the support frame 1 are provided with interconnected positioning grooves, and the end of the waste liquid needle away from the support frame 1 is located in the positioning groove and is on the same axis as the reaction cup placed on the rotating disk.

[0016] By adopting the above technical solution, a fixed block is connected to the support frame one, and interconnected positioning grooves are provided on the fixed block and the support frame one to support the end of the waste liquid needle away from the support frame two, thereby preventing the end of the waste liquid needle from shaking too much and being offset from the reaction cup when the driving member two drives the connecting frame to move and drives the waste liquid needle to approach the reaction cup, thereby preventing the waste liquid in the reaction cup from being discharged.

[0017] Optionally, an elastic member 1 is connected between the side of the support frame 2 close to the rotating disk and the waste liquid needle, and the elastic member 1 abuts against the fixed block when the driving member 2 drives the waste liquid needle to move toward the reaction cup.

[0018] By adopting the above technical solution, an elastic member 1 is connected and arranged between the side of the supporting frame 2 close to the rotating disk and the waste liquid needle. When the driving member 2 drives the connecting frame to move toward the fixed frame and the waste liquid needle moves toward the reaction cup, the elastic member 1 abuts against the fixed block on the supporting frame 1, and the elastic member 1 contracts, thereby playing a certain buffering role for the waste liquid needle to enter the reaction cup, thereby reducing the possibility of collision between the waste liquid needle and the bottom of the reaction cup. At the same time, when the driving member 2 drives the connecting frame away from the fixed frame, the elastic member 1 slowly resets, pushing the waste liquid needle to still stay in the reaction cup for a period of time, thereby reducing the possibility of waste liquid residue in the reaction cup.

[0019] Optionally, the mixing assembly includes cams arranged on both sides of the fixed frame, a mounting plate overlapped with the connecting frame is arranged above the fixed frame, the cam is rotatably arranged above the mounting plate, a driving member three for driving the cam to rotate is connected and arranged below the mounting plate, a fixing groove two in contact with the reaction cup is opened above the cam, and the fixing groove two is arranged offset from the rotation center of the cam.

[0020] By adopting the above technical scheme, a mounting plate overlapped with the connecting frame is arranged on the fixing frame, a cam is rotatably connected to the mounting plate, the connecting frame is driven to move on the mounting frame by the second driving member to drive the mounting plate to move, so that the cam moves at a position corresponding to the groove provided on the fixing seat, so as to prevent the cam from colliding with the fixing seat when moving up and down; a second fixing groove in contact with the reaction cup is provided at a position deviating from the rotation center of the cam, the cam moves with the mounting plate so that the second fixing groove contacts the bottom of the reaction cup; a third driving member is connected to the mounting plate, the cam is driven to rotate by the third driving member, so that the second fixing groove on the cam drives the reaction cup to rotate around the rotation center of the cam, the reaction cup is shaken, and the liquid in the reaction cup is mixed.

[0021] Optionally, one end of the mounting plate close to the connecting frame is connected to connecting plate 1, and both sides of the connecting frame are connected to connecting plate 2 in contact with connecting plate 1. The ends of connecting plate 1 and connecting plate 2 close to each other are bent, and the bent portion of connecting plate 1 is located above the bent portion of connecting plate 2 and overlaps with connecting plate 2.

[0022] By adopting the above technical solution, connecting plate one is connected to one end of the mounting plate close to the connecting frame, and connecting plate two is connected to the connecting frame. The bent portion of connecting plate one is located above the bent portion of connecting plate two and overlaps with connecting plate two, so that the mounting plate can move upward with the connecting frame, driving the cam to approach the reaction cup, preventing the reaction cup from being unable to contact the cam and affecting the mixing of the liquid in the reaction cup.

[0023] Optionally, the mounting plate and the side walls of the fixing frame are both connected with protrusions, and two elastic members are arranged between the protrusions, and the two elastic members pull the mounting plate to move toward a position close to the fixing frame; the fixing frame is provided with a connecting groove that is three-phase compatible with a driving member fixed to the mounting plate, and the mounting plate is provided with a positioning hole, in which a positioning rod connected to the fixing frame is inserted.

[0024] By adopting the above technical scheme, a protruding piece is connected to the side wall of the mounting plate and the fixing frame, and an elastic piece 2 is arranged between the protruding pieces. When the connecting frame moves toward the fixing frame under the drive of the driving piece 2, the elastic piece 2 contracts and pulls the mounting plate close to the fixing frame, so that the cam is away from the reaction cup, and the reaction cup can continue to rotate with the rotating disk; the mounting plate is positioned by the positioning hole provided on the mounting plate and the positioning rod connected to the fixing frame inserted in the positioning hole, so as to prevent the mounting plate from shifting when moving up and down, and the cam from being misaligned with the reaction cup, so as to prevent the liquid in the reaction cup from being improperly mixed; a connecting groove adapted to the driving piece 3 is provided on the fixing frame, so as to prevent the driving piece 3 from colliding with the fixing frame when the mounting plate moves downward, thereby affecting the operation of the device.

[0025] In summary, the present application includes at least one of the following beneficial technical effects: 1. A fixing seat is installed on the fixing frame, a fixing hole is provided at the center of the fixing seat, a rotating rod is rotatably set in the fixing hole, a driving member 1 connected to the rotating rod with a transmission is provided on the fixing frame, a rotating disk and the rotating rod are fixedly connected above the fixing seat, and the rotating rod is driven by the driving member 1 to drive the rotating disk to rotate; a fixing groove 1 is provided on the rotating disk, and a chamfer is provided on one side of the fixing groove 1 close to the fixing seat, so that the reaction cup placed in the fixing groove 1 can be shaken under the action of the mixing component, so as to prevent the reaction cup from being broken due to excessive contact area between the reaction cup and the side wall of the fixing groove 1 when the mixing component shakes the reaction cup; 2. A mounting plate overlapped with the connecting frame is arranged on the fixing frame, a cam is rotatably connected to the mounting plate, the connecting frame is driven to move on the mounting frame by the driving member 2 to drive the mounting plate to move, so that the cam moves at a position corresponding to the groove provided on the fixing seat, to prevent the cam from colliding with the fixing seat when moving up and down; a fixing groove 2 in contact with the reaction cup is provided at a position deviating from the rotation center of the cam, the cam moves with the mounting plate so that the fixing groove 2 contacts the bottom of the reaction cup; a driving member 3 is connected to the mounting plate, the cam is driven to rotate by the driving member 3, so that the fixing groove 2 on the cam drives the reaction cup to rotate around the rotation center of the cam, the reaction cup is shaken, and the liquid in the reaction cup is mixed; 3. A protruding piece is connected to the side wall of the mounting plate and the fixing frame, and an elastic piece 2 is arranged between the protruding pieces. When the connecting frame moves toward the fixing frame under the drive of the driving piece 2, the elastic piece 2 contracts and pulls the mounting plate close to the fixing frame, so that the cam is away from the reaction cup, and the reaction cup can continue to rotate with the rotating disk; the mounting plate is positioned by the positioning hole opened on the mounting plate and the positioning rod connected to the fixing frame inserted in the positioning hole to prevent the mounting plate from shifting when moving up and down, and the cam and the reaction cup from being misaligned, so that the liquid in the reaction cup is improperly mixed. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 is an overall schematic diagram of an automatic blood sample testing device in an embodiment; Figure 2 yes Figure 1 A partial enlarged view of middle A; Figure 3 yes Figure 1 A partial schematic diagram of B in the middle; Figure 4 It is a cross-sectional schematic diagram of a mixing component and a magnetic separation component of a blood sample testing device.

[0027] In the figure, 1, fixing frame; 12, supporting frame 1; 121, fixing block; 122, positioning groove; 123, adding cleaning liquid hole; 124, adding acid hole; 13, mounting frame; 14, connecting groove; 2, magnetic separation component; 21, fixing seat; 211, fixing hole; 212, connecting groove; 213, groove; 22, rotating rod; 23, rotating disk; 231, fixing groove 1; 24, driving member 1; 25, magnetic member; 3, Reaction cup; 4. Waste liquid discharge assembly; 41. Waste liquid needle; 411. Elastic part 1; 42. Connecting frame; 421. Connecting plate 2; 43. Support frame 2; 44. Driving part 2; 45. Screw; 5. Mixing assembly; 51. Cam; 511. Fixing groove 2; 52. Mounting plate; 521. Connecting plate 1; 522. Protruding part; 523. Elastic part 2; 524. Positioning hole; 53. Driving part 3; 54. Positioning rod. DETAILED DESCRIPTION

[0028] The following is combined with Figure 1 -Attached Figure 4 , further details of this application are given.

[0029] A blood sample automatic testing device, referring to Figure 1 and Figure 4, including a fixing frame 1, on which a metal fixing seat 21 in a magnetic separation component 2 is connected and fixed to the fixing frame 1 by bolts, a fixing hole 211 is opened at the center position of the fixing seat 21, and a rotating rod 22 is rotatably connected in the fixing hole 211 through a bearing and a sleeve, and a driving member 24 is fixedly connected with bolts on a side of the fixing frame 1 away from the fixing seat 21, and the driving member 24 is a stepping motor connected to a power supply, and a driving rod of the driving member 24 is connected to the rotating rod 22 through a pulley and a belt transmission, and a rotating disk 23 is fixedly connected to the end of the rotating rod 22 located above the fixing seat 21 by bolts, and the rotating rod 22 is driven to rotate by the driving member 24 to drive the rotating disk 23 to rotate in a step-by-step manner.

[0030] Reference Figure 1 and Figure 3 A mounting frame 13 extending upward is fixed on the fixing frame 1 with bolts, a connecting frame 42 is slidably connected to the mounting frame 13 through a guide rail and a slider, a screw rod 45 is rotatably connected to the connecting frame 42 through a thread, a driving member 2 44 is fixed on the fixing frame 1 by bolts, the driving member 2 44 is a driving motor connected to the power supply, the driving rod of the driving member 2 44 is fixedly connected to the screw rod 45 through a coupling, the screw rod 45 is driven to rotate by the driving member 2 44, and the connecting frame 42 is pushed to move on the mounting frame 13; a supporting frame 2 43 is fixed on the connecting frame 42 with bolts, and the supporting frame 2 43 is clamped with the waste liquid needle 41, so that the connecting frame 42 drives the waste liquid needle 41 to move in the direction close to the rotating disk 23; a supporting frame 12 is fixedly connected to the fixing frame 1 by a metal vertical rod and bolts, and the supporting frame 1 12 is located between the rotating disk 23 and the supporting frame 2 43.

[0031] Reference Figure 1 and Figure 2 A fixing groove 231 is evenly provided at the edge of the rotating disk 23, and a chamfer is provided on one side of the fixing groove 231 close to the fixing seat 21, and the reaction cup 3 is placed in the fixing groove 231 on the rotating plate; a connecting groove 212 corresponding to the position of the reaction cup 3 is provided on the side wall of the metal fixing seat 21, and a magnetic member 25 is adsorbed and fixed in the connecting groove 212, and the magnetic member 25 is a strong magnet. After the antigen in the blood sample in the reaction cup 3 combines with the magnetic particles, the magnetic member 25 is adsorbed and fixed in the reaction cup 3.

[0032] Reference Figure 1 and Figure 3A cleaning liquid adding hole 123 for adding cleaning liquid is provided at one end of the support frame 12 above the rotating disk 23, and is located on the same axis as the reaction cup 3 placed on the rotating disk 23, and cleaning liquid is added to the reaction cup 3 for cleaning; an acid adding hole 124 for adding acid to the reaction cup 3 is provided at one end of the support frame 12 away from the cleaning liquid adding hole 123, and is located on the same axis as the reaction cup 3 placed on the rotating disk 23, and acid is added to the reaction cup 3 after the liquid in the reaction cup 3 is cleaned, so that the liquid in the reaction cup 3 reacts.

[0033] Reference Figure 1 and Figure 3 A metal fixing block 121 is fixed to the support frame 12 by bolts, and a communicating positioning groove 122 is provided on the fixing block 121 and the support frame 12. The waste liquid needle 41 on the support frame 2 43 is on the same axis as the positioning groove 122. When the waste liquid needle 41 moves toward the rotating disk 23 along with the support frame 2 43, the waste liquid needle 41 is supported by the positioning groove 122 to prevent the end of the waste liquid needle 41 close to the reaction cup 3 from being offset from the reaction cup 3; an elastic member 411 is fixed to the side of the support frame 2 43 close to the rotating disk 23 and the waste liquid needle 41. The elastic member 411 is a spring. When the waste liquid needle 41 moves toward the reaction cup 3, the spring and the fixing block 121 are pressed against each other and contracted, which has a certain buffering effect on the waste liquid needle 41 entering the reaction cup 3, thereby reducing the possibility of the waste liquid needle 41 colliding with the bottom of the reaction cup 3.

[0034] Reference Figure 1 , Figure 2 and Figure 4 A second connecting plate 421 is fixed on both sides of the connecting frame 42 by bolts, and a first connecting plate 521 is overlapped on the second connecting plate 421. The bending portion of the first connecting plate 521 is located above the bending portion of the second connecting plate 421. A mounting plate 52 is fixedly connected to the end of the first connecting plate 521 away from the connecting frame 42 by bolts. The mounting plate 52 is located below the rotating plate, so that the mounting plate 52 moves with the connecting frame 42 to the side close to the rotating plate; a cam 51 is rotatably connected to the mounting plate 52 located on both sides of the fixed seat 21 through a bearing, and a second fixing groove 511 is opened at the eccentric position of the cam 51. The second fixing groove 511 is moved along the cam 51. When the mounting plate 52 moves upward, it contacts the bottom of the reaction cup 3. A groove 213 is provided at a position corresponding to the fixing seat 21 and the cam 51 to prevent the cam 51 from colliding with the fixing seat 21 when the connecting frame 42 drives the connecting plate 1 521 and the mounting plate 52 to move upward through the connecting plate 2 421. A driving member 3 53 is fixed by bolts on the side of the mounting plate 52 away from the cam 51. The driving member 3 53 is a driving motor connected to a power source. The driving rod of the driving member 3 53 is connected and fixed to the cam 51 by a flat key. The driving member 3 53 drives the cam 51 to rotate, so that the fixing groove 2 511 at the eccentric position of the cam 51 drives the reaction cup 3 to shake.

[0035] Reference Figure 1 and Figure 2 The mounting plate 52 and the side wall of the fixing frame 1 are fixedly connected with a protruding piece 522, which is a metal screw with a stop cap that is threadedly connected to the mounting plate 52 and the fixing frame 1. An elastic piece 523 is fixedly connected between the protruding pieces 522, and the elastic piece 523 is a contraction spring. After the liquid in the reaction cup 3 is mixed, when the connecting frame 42 moves toward the fixing frame 1 under the drive of the driving piece 44, the elastic piece 523 contracts and pulls the mounting plate 52 close to the fixing frame 1, so that the cam 51 is away from the reaction cup 3, so that the reaction cup 3 can move with The rotating disk 23 continues to rotate; a connecting groove 14 adapted to the driving member three 53 is provided on the fixing frame 1 to prevent the driving member three 53 from colliding with the fixing frame 1 when the mounting plate 52 moves together with the connecting frame 42, thereby affecting the operation of the device; a positioning hole 524 is provided on the mounting plate 52, and a metal positioning rod 54 that fits the positioning hole 524 is fixed to the fixing frame 1 with bolts to position the mounting plate 52 to prevent the positioning groove 1222 on the cam 51 from being misaligned with the reaction cup 3 when the mounting plate 52 moves up and down.

[0036] The implementation principle of the embodiment of the present application is: The reaction cup 3 is placed in the positioning groove 1222 on the rotating disk 23, and the driving member 1 24 drives the rotating rod 22 to drive the rotating disk 23 to rotate, so that the reaction cup 3 and the cleaning liquid adding hole 123 on the support frame 12 are on the same axis, and the cleaning liquid is added to the reaction cup 3 through the cleaning liquid adding hole 123, and then the driving member 2 44 drives the connecting frame 42 to move up, so that the connecting frame 42 drives the connecting plate 1 521 and the mounting plate 52 to move up through the connecting plate 2 421, so that the fixing groove 2 511 on the cam 51 on the mounting plate 52 is aligned with the reaction cup 3. The bottom of the cup 3 is in contact, and the driving member 3 53 drives the cam 51 to rotate, and shakes the reaction cup 3 to mix the liquid in the reaction cup 3; then the driving member 2 44 drives the connecting frame 42 to move downward, and the elastic member 2 523 between the mounting plate 52 and the fixing frame 1 contracts, pulling the mounting plate 52 to move downward, so that the cam 51 is away from the reaction cup 3, and the driving member 1 24 drives the rotating disk 23 to continue to rotate, and the magnetic member 25 fixed in the connecting groove 212 on the fixing seat 21 adsorbs and fixes the magnetic particles combined with the antigen in the reaction cup 3 , the reaction cup 3 on the rotating disk 23 and the positioning groove 122 on the support frame 12 are located on the same axis; the driving member 2 44 drives the connecting frame 42 to continue to move downward, so that the waste liquid needle 41 on the support frame 2 43 fixed on the connecting frame 42 moves toward the reaction cup 3 through the positioning groove 122 on the support frame 12, and the waste liquid generated after washing in the reaction cup 3 is extracted, and then the driving member 2 44 drives the connecting frame 42 to move upward, driving the waste liquid needle 41 away from the reaction cup 3; the driving member 1 24 drives the rotating disk 23 to continue to rotate, and the waste liquid needle 41 moves away from the reaction cup 3. 2 is on the same axis, and acid is added to the reaction cup 3 that discharges waste liquid after cleaning, so as to react with the antigens combined with magnetic particles remaining in the reaction cup 3; then the driving member 2 44 drives the connecting frame 42 to continue to move upward, so that the connecting frame 42 drives the mounting plate 52 to move upward, so that the cam 51 on the mounting plate 52 located at the same position as the acid adding hole 124 contacts the bottom of the reaction cup 3 after acid addition, and the driving member 3 53 drives the cam 51 to rotate and drive the reaction cup 3 to shake, so as to evenly shake the liquid in the reaction cup 3. The driving member 2 44 drives the connecting frame 42 to drive the cam 51 on the mounting plate 52 to move, so that the reaction cup 3 placed on the rotating disk 23 can be quickly and timely shaken after the cleaning liquid is added and the reaction cup 3 after acid addition after the reaction cup 3 is transferred, thereby shortening the mixing cycle for mixing the reaction cup 3.

[0037] The embodiments of this specific implementation are all preferred embodiments of the present application, and are not intended to limit the protection scope of the present application. The same components are represented by the same figure marks. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A blood sample automatic testing device, comprising a fixing frame (1), characterized in that: A magnetic separation component (2) for placing a reaction cup (3) is arranged above the fixing frame (1); a waste liquid discharge component (4) corresponding to the reaction cup (3) is arranged above the magnetic separation component (2); and mixing components (5) are arranged on both sides of the magnetic separation component (2) on the fixing frame (1); the mixing components (5) are in contact with the bottom of the reaction cup (3); The magnetic separation component (2) comprises a fixing seat (21) arranged above the fixing frame (1), the fixing seat (21) is provided with a fixing hole (211), a rotating rod (22) is rotatably arranged in the fixing hole (211), the rotating rod (22) is located above the fixing seat (21) and is fixedly connected to a rotating disk (23), a driving member (24) is connected to the rotating rod (22) and is belt-drivenly connected to the driving member (24) below the fixing frame (1), a fixing groove (231) corresponding to the reaction cup (3) is arranged on the edge of the rotating disk (23), the fixing groove (231) is in contact with the edge of the reaction cup (3), and a chamfer is arranged on a side of the fixing groove (231) close to the fixing frame (1); The fixing frame (1) is located above the fixing seat (21) and is connected to a supporting frame 1 (12). The supporting frame 1 (12) is located on a side of the waste liquid discharge component (4) close to the rotating disk (23). One end of the supporting frame 1 (12) is provided with a cleaning liquid adding hole (123) corresponding to the reaction cup (3). The other end of the supporting frame 1 (12) is provided with an acid adding hole (124) corresponding to the reaction cup (3). The acid adding hole (124), the cleaning liquid adding hole (123) and the mixing component (5) are located on the same axis.

2. The blood sample automatic testing device according to claim 1, characterized in that: The side wall of the fixing seat (21) is provided with a connection groove (212), in which a magnetic member (25) for adsorbing antigens combined with magnetic particles in the reaction cup (3) is connected, and the side wall of the fixing seat (21) is provided with a groove (213) corresponding to the mixing component (5).

3. The automatic blood sample testing device according to claim 1, characterized in that: The waste liquid discharge assembly (4) comprises a waste liquid needle (41), the fixed frame (1) is connected to a mounting frame (13) extending upward, the mounting frame (13) is slidably connected to a connecting frame (42), the connecting frame (42) is in contact with a mixing assembly (5), a second support frame (43) is connected above the connecting frame (42), the second support frame (43) is located above the first support frame (12) and is connected to the waste liquid needle (41), and a second driving member (44) is connected below the fixed frame (1), the driving rod of the second driving member (44) is fixedly connected to a screw rod (45), and the screw rod (45) is rotatably connected to the connecting frame (42).

4. The automatic blood sample testing device according to claim 3, characterized in that: A fixing block (121) is connected to one side of the support frame 1 (12) close to the support frame 2 (43); the fixing block (121) and the support frame 1 (12) are provided with mutually communicating positioning grooves (122); an end of the waste liquid needle (41) away from the support frame 1 (12) is located in the positioning groove (122) and is located on the same axis as the reaction cup (3) placed on the rotating disk (23).

5. The automatic blood sample testing device according to claim 4, characterized in that: An elastic member 1 (411) is connected between the side of the support frame 2 (43) close to the rotating disk (23) and the waste liquid needle (41), and the elastic member 1 (411) abuts against the fixed block (121) when the driving member 2 (44) drives the waste liquid needle (41) to move toward the reaction cup (3).

6. The blood sample automatic testing device according to claim 3, characterized in that: The mixing assembly (5) comprises cams (51) arranged on both sides of a fixing frame (1); a mounting plate (52) overlapped with a connecting frame (42) is arranged above the fixing frame (1); the cam (51) is rotatably arranged above the mounting plate (52); a driving member (53) for driving the cam (51) to rotate is connected to the lower side of the mounting plate (52); a fixing groove (511) for contacting a reaction cup (3) is provided above the cam (51); and the fixing groove (511) is arranged offset from the rotation center of the cam (51).

7. The automatic blood sample testing device according to claim 6, characterized in that: One end of the mounting plate (52) close to the connecting frame (42) is connected to a connecting plate 1 (521), and both sides of the connecting frame (42) are connected to connecting plates 2 (421) in contact with the connecting plate 1 (521). The connecting plate 1 (521) and the connecting plate 2 (421) are bent at one end close to each other, and the bent portion of the connecting plate 1 (521) is located above the bent portion of the connecting plate 2 (421) and overlaps with the connecting plate 2 (421).

8. The blood sample automatic testing device according to claim 7, characterized in that: The mounting plate (52) and the side wall of the fixing frame (1) are both connected to be provided with a protruding member (522), and a second elastic member (523) is provided between the protruding members (522), and the second elastic member (523) pulls the mounting plate (52) to move toward a position close to the fixing frame (1); the fixing frame (1) is provided with a connecting groove (14) adapted to a third driving member (53) fixed to the mounting plate (52), and the mounting plate (52) is provided with a positioning hole (524), and a positioning rod (54) connected to the fixing frame (1) is inserted into the positioning hole (524).

Citation Information

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