Pressurizing and filtering device for preparing drug intermediates

Abstract

The utility model provides a pressure filtration device for preparing drug intermediates, and relates to the technical field of drug intermediate related equipment, the pressure filtration device comprises a filtration box, one end of the outer top of the filtration box is communicated and connected with a feed pipe, and the other end of the outer top of the filtration box is connected with a pressure pump; the pressurizing end of the pressurizing pump is communicated and connected with the filtering box through a pipeline, and a filtering assembly used for filtering the drug intermediates in a layered mode is arranged in the filtering box. The driving motor is used as a power source to drive the driving rod to rotate, and meanwhile, under the meshing characteristic of the main bevel gear, the first driven bevel gear and the second driven bevel gear, the rotating rod and the limiting sleeve can drive the first annular filtering frame and the second annular filtering frame to synchronously rotate forwards and backwards; furthermore, the contact area between the drug intermediate and the first and second filtering frames is increased under the action of centrifugal force, so that the layered filtering treatment effect is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of equipment related to drug intermediates, in particular to a pressure filtering device for preparing drug intermediates. Background Art

[0002] The so-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product can be produced in ordinary chemical plants. As long as it reaches a certain level, it can be used in the synthesis of drugs. When preparing pharmaceutical intermediates, they need to be filtered.

[0003] At present, most general filtration devices adopt the processing form of layered filtration. For example, Chinese patent publication number CN218357799U discloses a multi-stage pressurized filtration device for preparing pharmaceutical intermediates, including a box body and a box door, a feed port is arranged at the left end of the upper surface of the box body, and a pressure pump is arranged in the middle of the upper surface of the box body. In the above-mentioned public document, the pressurized pump and the material discharge inclined plate are used to enable the pharmaceutical intermediates to be discharged quickly under the action of the material discharge inclined plate, and the pharmaceutical intermediates can be prevented from being blocked during the discharge under the action of the pressurized pump, thereby promoting the discharge process of the pharmaceutical intermediates. However, when the patent is used, due to the small contact area between the pharmaceutical intermediate and the filter frame, the layered filtration effect of the pharmaceutical intermediate is not good, thereby making the filtration work efficiency low. To this end, those skilled in the art provide a pressurized filtration device for preparing pharmaceutical intermediates to solve the problems raised in the above-mentioned background technology. Utility Model Content

[0004] In view of the shortcomings of the prior art, the utility model provides a pressurized filtration device for preparing drug intermediates, which can effectively solve the problem in the background technology that the contact area between the drug intermediates and the filter frame is small, resulting in poor layered filtration effect of the drug intermediates, thereby resulting in low filtration efficiency.

[0005] To achieve the above purpose, the utility model is implemented by the following technical scheme: a pressure filtration device for preparing a drug intermediate, comprising a filter box, one end of the outer top of the filter box is connected with a feed pipe, the other end of the outer top of the filter box is connected with a pressure pump, and the boosting end of the pressure pump is connected with the filter box through a pipeline, and a filter assembly for layered filtration of the drug intermediate is arranged inside the filter box;

[0006] A driving component for driving the filter assembly to perform synchronous forward and reverse rotation is provided at the middle position of an outer side wall of the filter box;

[0007] An opening and a discharge port are respectively provided at the middle and bottom of the other side outer wall of the filter box, and a first arc-shaped sealing plate and a second arc-shaped sealing plate are respectively provided at the opening and the discharge port on the outer wall of the filter box.

[0008] As a further technical solution of the utility model, the filter assembly includes a fixed rod fixedly installed in the middle position of the inner bottom surface of the filter box, the outer top of the fixed rod is rotatably connected to a rotating rod, the end of the rotating rod is rotatably connected to the inner top surface of the filter box, and the first annular filter frame and the first driven bevel gear are respectively installed at both ends of the outer surface of the rotating rod;

[0009] The top end of the outer wall of the fixing rod is rotatably connected with a limiting sleeve, and the outer surface of the limiting sleeve is respectively connected with a second driven bevel gear and a second annular filter frame.

[0010] As a further technical solution of the utility model, the drive assembly includes a drive motor fixedly installed in the middle position of the outer side wall of the filter box, the output end of the drive motor is fixedly connected to a drive rod, one end of the drive rod extends to the interior of the filter box, and a main bevel gear is also fixedly installed on the outer surface, the main bevel gear is located between the first driven bevel gear and the second driven bevel gear, and is meshed with each other.

[0011] As a further technical solution of the utility model, an inverted conical material introduction ring is connected to the inner wall of the filter box and located between the first annular filter frame and the first driven bevel gear, and the material introduction ring is sleeved on the outside of the rotating rod.

[0012] As a further technical solution of the utility model, a limiting ring is connected to the outer side wall of the first annular filter frame and the second annular filter, and the outer surface of the limiting ring is slidably inserted into the matching limiting groove opened on the inner side wall of the filter box.

[0013] As a further technical solution of the utility model, the inner bottom end of the filter box is inclined, and its inclined end corresponds to the discharge port.

[0014] As a further technical solution of the utility model, the first arc-shaped sealing plate and the second arc-shaped sealing plate are connected to the filter box through a movable hinge and a lock.

[0015] As a further technical solution of the utility model, support columns are fixedly installed at the four corners of the outer bottom of the filter box.

[0016] The utility model provides a pressure filtration device for preparing a pharmaceutical intermediate, which has the following beneficial effects compared with the prior art:

[0017] 1. A pressurized filtration device for preparing a drug intermediate. When the drug intermediate needs to be filtered, a driving motor can be used as a power source to drive a driving rod to rotate. At the same time, under the meshing characteristics of the main bevel gear and the first and second driven bevel gears, the rotating rod and the limiting sleeve can drive the first and second annular filter frames to rotate synchronously forward and reversely, so that the drug intermediate increases the contact area with the first and second filter frames under the action of centrifugal force, thereby improving the effect of layered filtration, and secondly reducing the risk of clogging, avoiding the problem that the drug intermediate has a small contact area with the filter frame, resulting in poor layered filtration effect of the drug intermediate, which easily leads to a long processing time and thus low processing efficiency, thereby helping to improve the working efficiency of the filtration process.

[0018] 2. A pressurized filtration device for preparing drug intermediates, which facilitates the opening and closing of the first and second arc-shaped sealing plates through movable hinges and locks, thereby facilitating the cleaning of the first and second annular filter frames and the discharge of the filtered drug intermediates, further improving the applicability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of a pressure filtration device for preparing a pharmaceutical intermediate;

[0020] Figure 2 It is a schematic diagram of the cross-sectional three-dimensional structure of a pressure filtration device for preparing a pharmaceutical intermediate;

[0021] Figure 3 The present invention is a schematic diagram of the structure of a filtering component of a pressure filtering device for preparing a pharmaceutical intermediate.

[0022] In the figure: 1. filter box; 2. feed pipe; 3. pressure pump; 4. open mouth; 5. discharge port; 6. first arc-shaped sealing plate; 7. second arc-shaped sealing plate; 8. support column; 9. drive motor; 10. fixed rod; 11. rotating rod; 12. main bevel gear; 13. first driven bevel gear; 14. second driven bevel gear; 15. first annular filter frame; 16. second annular filter frame; 17. drive rod; 18. guide ring; 19. limit ring; 20. limit groove. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0024] See also Figure 1-3 As shown, a pressure filtration device for preparing a drug intermediate comprises a filter box 1, one end of the outer top of the filter box 1 is connected with a feed pipe 2, the other end of the outer top of the filter box 1 is connected with a pressure pump 3, and the boosting end of the pressure pump 3 is connected with the filter box 1 through a pipeline, and a filter assembly for layered filtration of the drug intermediate is arranged inside the filter box 1, and the filter assembly comprises a fixed rod 10 fixedly installed at the middle position of the inner bottom surface of the filter box 1, the outer top of the fixed rod 10 is rotatably connected with a rotating rod 11, the end of the rotating rod 11 is rotatably connected to the inner top surface of the filter box 1, and the two ends of the outer surface of the rotating rod 11 are respectively arranged A first annular filter frame 15 and a first driven bevel gear 13 are installed, and a limiting sleeve is rotatably connected to the top position of the outer wall of the fixed rod 10. The second driven bevel gear 14 and the second annular filter frame 16 are respectively connected to the outer surfaces of the limiting sleeve. An inverted cone-shaped feed ring 18 is connected to the inner wall of the filter box 1 and is located between the first annular filter frame 15 and the first driven bevel gear 13. The feed ring 18 is sleeved on the outside of the rotating rod 11. A limiting ring 19 is connected to the outer walls of the first annular filter frame 15 and the second annular filter frame 16. The outer surface of the limiting ring 19 is slidably inserted into the matching limiting groove 20 opened on the inner wall of the filter box 1. The drug intermediate can be transported to the first annular filter frame 15 through the feed pipe 2, and the first annular filter frame 15 is rotated by rotating the rotating rod 11, and the drug intermediate moves to both sides under the action of centrifugal force, thereby increasing the contact area with the first annular filter frame 15, and then flows into the introduction ring 18 through the filter hole at the bottom, and under the auxiliary drainage of the introduction ring 18, the drug intermediate is introduced into the second annular filter frame 16, and rotated on the fixed rod 10 through the limit sleeve, so that the second annular filter frame 16 is rotated, and then filtered again, and then flows into the inner bottom surface of the filter box 1 through the filter hole at the bottom of the second annular filter frame 16 for storage. Since the filter hole size of the first annular filter frame 15 is larger than the filter hole size of the second annular filter frame 16, the first annular filter frame 15 and the second annular filter frame 16 can achieve the effect of graded filtration of the drug intermediate, which is conducive to improving the efficiency of filtering the drug intermediate. At the same time, the pressure pump 3 is an air booster pump, so that the purpose of continuously pressurizing the filter box 1 can be achieved to avoid blockage of the drug intermediate and promote the filtering process of the drug intermediate. Secondly, when rotating, the limiting ring 19 rotates in the inner side of the limiting groove 20, so that the first annular filter frame 15 and the second annular filter frame 16 are more stable when rotating.

[0025] A driving assembly for driving the filter assembly to perform synchronous forward and reverse rotation is provided at the middle position of the outer wall of one side of the filter box 1. The driving assembly includes a driving motor 9 fixedly installed at the middle position of the outer wall of the filter box 1. The output end of the driving motor 9 is fixedly connected to a driving rod 17. One end of the driving rod 17 extends to the inside of the filter box 1, and a main bevel gear 12 is also fixedly installed on the outer surface. The main bevel gear 12 is located between the first driven bevel gear 13 and the second driven bevel gear 14, and is meshed and connected with each other. By using the driving motor 9 as a power source, the driving rod 17 is driven to rotate, so that the main bevel gear 12 drives the first driven bevel gear 13 and the second driven bevel gear 14 to perform synchronous forward and reverse rotation.

[0026] An opening 4 and a discharge port 5 are respectively provided at the middle and bottom of the other side outer wall of the filter box 1. A first arc-shaped sealing plate 6 and a second arc-shaped sealing plate 7 are respectively provided at the opening 4 and the discharge port 5 on the outer wall of the filter box 1. The inner bottom end of the filter box 1 is inclined, and its inclined end corresponds to the discharge port 5. The first arc-shaped sealing plate 6 and the second arc-shaped sealing plate 7 are connected to the filter box 1 through a movable hinge and a lock. Support columns 8 are respectively fixedly installed at the four corners of the outer bottom of the filter box 1. The support columns 8 play a supporting and fixing role for the filter box 1. After the drug intermediate is filtered, the second arc-shaped sealing plate 7 can be opened by the mutual cooperation of the movable hinge and the lock, and then the drug intermediate can be taken out. Since the inner bottom surface of the filter box 1 is inclined, it is convenient for the drug intermediate to flow out. At the same time, by opening the first arc-shaped sealing plate 6, it is convenient to clean the impurities in the first annular filter frame 15 and the second annular filter frame 16.

[0027] The working principle of the utility model is as follows: the drug intermediate to be filtered is transported to the first annular filter frame 15 along the feed pipe 2, and then the main bevel gear 12 on the drive rod 17 is driven to rotate by the driving motor 9, and then the first driven bevel gear 13 and the second driven bevel gear 14 are driven to rotate synchronously under the meshing characteristics of the gears, so that the first annular filter frame 15 and the second annular filter frame 16 are synchronously rotated in positive and negative directions, so that the drug intermediate moves to both sides under the action of centrifugal force, thereby increasing the filtering contact area between the drug intermediate and the first annular filter frame 15 and the second annular filter frame 16, and at the same time, the first annular filter frame 15 and the second annular filter frame 16 can promote the drug intermediate to be layered filtered, which is beneficial to improve the efficiency of filtering the drug intermediate, and secondly, the pressure pump 3 can be turned on to pressurize the drug intermediate to promote the blocked drug intermediate to be discharged, and then fall onto the inner bottom surface of the filter box 1.

[0028] At the same time, when the drug intermediate is filtered, the second arc-shaped sealing plate 7 can be opened by the movable hinge and the lock, and then the drug intermediate can be taken out. Then, the first arc-shaped sealing plate 6 is opened to clean the impurities in the first annular filter frame 15 and the second annular filter frame 16.

[0029] The above is only a preferred embodiment of the present invention. It should be noted that, for ordinary technicians in the technical field, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention shall be implemented according to the conventional means in the field unless otherwise specified and limited.

Claims

1. A pressure filtration device for preparing a pharmaceutical intermediate, characterized in that: The invention comprises a filter box (1), wherein one end of the outer top of the filter box (1) is connected to a feed pipe (2), the other end of the outer top of the filter box (1) is connected to a pressure pump (3), and the boosting end of the pressure pump (3) is connected to the filter box (1) through a pipeline, and a filter assembly for performing layered filtration on a drug intermediate is arranged inside the filter box (1); A driving component for driving the filter component to perform synchronous forward and reverse rotation is provided at the middle position of an outer side wall of the filter box (1); An opening (4) and a discharge port (5) are respectively provided at the middle and bottom of the other side outer wall of the filter box (1), and a first arc-shaped sealing plate (6) and a second arc-shaped sealing plate (7) are respectively provided at the opening (4) and the discharge port (5) on the outer wall of the filter box (1).

2. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 1, characterized in that: The filter assembly comprises a fixed rod (10) fixedly mounted on the middle position of the inner bottom surface of the filter box (1); the outer top of the fixed rod (10) is rotatably connected to a rotating rod (11); the end of the rotating rod (11) is rotatably connected to the inner top surface of the filter box (1); and the first annular filter frame (15) and the first driven bevel gear (13) are respectively mounted on the two ends of the outer surface of the rotating rod (11); A limiting sleeve is rotatably connected at the top end of the outer wall of the fixing rod (10), and a second driven bevel gear (14) and a second annular filter frame (16) are respectively connected to the outer surface of the limiting sleeve.

3. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 2, characterized in that: The driving assembly comprises a driving motor (9) fixedly mounted on the middle of the outer wall of the filter box (1); the output end of the driving motor (9) is fixedly connected to a driving rod (17); one end of the driving rod (17) extends into the interior of the filter box (1), and a main bevel gear (12) is fixedly mounted on the outer surface; the main bevel gear (12) is located between a first driven bevel gear (13) and a second driven bevel gear (14), and is meshed with each other.

4. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 2, characterized in that: An inverted conical material introduction ring (18) is connected to the inner wall of the filter box (1) and is located between the first annular filter frame (15) and the first driven bevel gear (13). The material introduction ring (18) is sleeved on the outside of the rotating rod (11).

5. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 2, characterized in that: A limiting ring (19) is connected to the outer side walls of the first annular filter frame (15) and the second annular filter frame (16), and the outer surface of the limiting ring (19) is slidably inserted into a matching limiting groove (20) provided on the inner side wall of the filter box (1).

6. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 1, characterized in that: The inner bottom end of the filter box (1) is inclined, and its inclined end corresponds to the discharge port (5).

7. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 1, characterized in that: The first arc-shaped sealing plate (6) and the second arc-shaped sealing plate (7) are connected to the filter box (1) via a movable hinge and a lock.

8. A pressure filtration device for preparing a pharmaceutical intermediate according to claim 1, characterized in that: Support columns (8) are respectively fixedly mounted at the four corners of the outer bottom of the filter box (1).

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