Kit for multiple detection of drug-resistant genes of pulmonary tuberculosis

By designing sample oscillation mechanism and auxiliary storage components in the kit, the problem of insufficient adjustment of the existing reagent detection kits being unable to oscillate reagents and storage environment is solved, and higher detection accuracy and sample storage time are achieved.

CN222592297UActive Publication Date: 2025-03-11SICHUAN UNIV
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Patent Information

Application Number
CN202421040830.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-14
Publication Date
2025-03-11
Estimated Expiration
2034-05-14

AI Technical Summary

Technical Problem

The existing reagent detection kit cannot oscillate the reagent reservoir tube during use, resulting in poor oscillation effect and affecting the accuracy of the detection data. At the same time, the storage function of the reagent detection kit is insufficient and cannot be adjusted according to the storage environment requirements, which affects the storage time of the sample.

Method used

A kit for multiple detection of drug-resistant genes for tuberculosis was designed, including sample oscillation mechanism and auxiliary storage components. The sample oscillation mechanism generates vibration through a micro vibration motor, so that the reagent can be fully vibrated. The auxiliary storage component can place ice cubes or heating materials as needed to extend the storage time of the sample.

Benefits of technology

Through the use of the sample oscillation mechanism, the accuracy of the detection sample data is improved; through the design of auxiliary storage components, the storage time of the sample is extended, making the use of the kit more practical and convenient.

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Abstract

The utility model relates to a kit for multiple detection of drug-resistant genes of pulmonary tuberculosis, which belongs to the technical field of reagent detection and comprises a detection box body, a sample oscillating mechanism and an auxiliary storage component are arranged on the detection box body, and the sample oscillating mechanism is arranged on the auxiliary storage component. The sample oscillation mechanism comprises a partition plate fixedly mounted in the detection box body. According to the kit for multiple detection of the drug-resistant genes of the pulmonary tuberculosis, through the sample oscillation mechanism and the auxiliary storage assembly, under the mutual cooperation of all structures on the detection box body, a sample containing the drug-resistant genes of the pulmonary tuberculosis can be placed on a placement rack, and a reagent is fully oscillated by virtue of vibration generated by a micro vibration motor, so that the detection accuracy of the drug-resistant genes of the pulmonary tuberculosis is improved; the sample detection kit is simple in structure, convenient to use and capable of facilitating improvement of accuracy of subsequent detection sample data, ice blocks or heating materials can be placed in the material placing box according to sample storage requirements, so that the preservation time of samples is prolonged, and the sample detection kit is more practical and convenient to use.
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Description

Technical Field

[0001] The utility model relates to the technical field of reagent detection, in particular to a reagent kit for multiple detection of tuberculosis drug resistance genes. Background Art

[0002] Pulmonary tuberculosis, also often referred to as "pulmonary tuberculosis", is an infectious respiratory disease caused by infection with Mycobacterium tuberculosis. The disease mainly forms lesions in the lung tissue, trachea, bronchi and pleura. A detection kit is a device used to detect diseases, and the device can be packaged during transportation, and the reagents in the package can be taken out for testing when testing is needed. Depending on the composition of the reagents included in the detection kit, the detection kit can be used to detect different diseases.

[0003] Existing detection kits have some limitations and deficiencies in design and function. The reagent containing tube cannot be oscillated during use, and the staff needs to oscillate it manually during actual testing. This method is likely to result in poor oscillation effect, thus affecting the accuracy of the test data. In addition, general reagent test kits only have a simple storage function, which is not convenient for adjustment according to the storage environment requirements, thus affecting the storage time of the sample. Therefore, a kit for multiple detection of tuberculosis drug-resistant genes is proposed to solve the above technical problems. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a kit for multiple detection of tuberculosis drug-resistant genes, which has the advantages of shaking reagents, adjusting the storage environment, improving the accuracy of test results, and extending the sample storage time. It solves some limitations and deficiencies in the design and function of existing detection kits. The reagent containing tube cannot be shaken during use, and the staff needs to shake it manually during actual testing. This method is likely to cause poor shaking effect, thereby affecting the accuracy of the test data. In addition, general reagent detection boxes only have a simple storage function, which is not convenient for adjustment according to the storage environment requirements, thus affecting the storage time of the sample.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a reagent kit for multiple detection of drug-resistant genes of pulmonary tuberculosis, comprising a detection box body, a sample oscillation mechanism is provided on the detection box body, and an auxiliary storage component is provided on the detection box body;

[0006] The sample oscillation mechanism comprises a partition plate fixedly mounted inside the detection box body, a mounting seat is fixedly mounted on the left side of the partition plate and the left inner wall of the detection box body, a fixing rod is fixedly mounted inside the two mounting seats, a movable connecting rod is slidably connected to the outer side of the two fixing rods, a placing rack is fixedly mounted on the opposite side of the two movable connecting rods, and a buffer spring sleeved on the outer side of the fixing rod is fixedly mounted on the top and bottom of the movable connecting rod;

[0007] A connecting frame is fixedly installed on the bottom of the placing frame, a placing base is fixedly installed on the inner side of the connecting frame, a micro vibration motor located at the bottom of the placing base is arranged on the connecting frame, a shock absorbing seat is fixedly installed on the inner bottom wall of the detection box body, a shock absorbing spring is fixedly installed inside the shock absorbing seat, and a support rod extending to the top of the shock absorbing seat and fixedly connected to the bottom of the connecting frame is fixedly installed on the top of the shock absorbing spring.

[0008] Furthermore, the auxiliary storage component includes a fixed block fixedly installed on the right side of the partition plate and the right inner wall of the detection box body, a sample storage box is movably placed on the top of the fixed block, a limiting plate is arranged inside the sample storage box, and a material placement box is movably inserted into the bottom of the fixed block.

[0009] Furthermore, limiting grooves are provided on the inner walls on opposite sides of the two mounting seats, and the movable connecting rod is slidably connected to the inner wall of the mounting seat through the limiting grooves.

[0010] Furthermore, a groove is provided on the top of the placing base, a silicone protective pad is provided inside the placing frame, and a mounting hole is provided inside the silicone protective pad.

[0011] Furthermore, a first through hole is formed on the top of the shock absorbing seat, and the support rod extends to the top of the shock absorbing seat through the first through hole.

[0012] Furthermore, a plurality of placement holes are provided inside the limiting plate, and the placement holes are distributed from small to large.

[0013] Furthermore, a mounting slot is provided at the bottom of the fixed block, a plug-in slot is provided at the front of the detection box body, and the material placement box extends through the plug-in slot to the inside of the detection box body and is slidably plugged into the mounting slot at the bottom of the fixed block.

[0014] Compared with the prior art, the technical solution of this application has the following beneficial effects:

[0015] The test kit for multiple detection of tuberculosis drug-resistant genes can place samples containing tuberculosis drug-resistant genes on a storage rack through the arrangement of a sample oscillation mechanism and an auxiliary storage component, with the cooperation of various structures on the test kit body, and fully oscillate the reagents by using the vibration generated by a micro-vibration motor, thereby helping to improve the accuracy of subsequent test sample data. In addition, according to the sample storage requirements, ice cubes or heated materials can be placed inside the material storage box, thereby extending the storage time of the samples, making the use of the sample test kit more practical and convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic cross-sectional view of the structure of the utility model;

[0017] Figure 2 It is a side view schematic diagram of the structure of the utility model;

[0018] Figure 3 It is a three-dimensional schematic diagram of the structure of the utility model.

[0019] In the figure: 1. Test box body; 2. Partition plate; 3. Mounting seat; 4. Fixing rod; 5. Movable connecting rod; 6. Placement rack; 7. Buffer spring; 8. Connecting rack; 9. Placement base; 10. Micro vibration motor; 11. Shock-absorbing seat; 12. Buffer spring; 13. Support rod; 14. Fixing block; 15. Sample storage box; 16. Limiting plate; 17. Material placement box. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] See also Figure 1-3 A reagent kit for multiple detection of tuberculosis drug-resistant genes in this embodiment includes a detection box body 1, a sample oscillation mechanism is provided on the detection box body 1, and an auxiliary storage component is provided on the detection box body 1.

[0022] See also Figure 1 , Figure 2 and Figure 3 The sample oscillation mechanism includes a partition plate 2 fixedly installed inside the detection box body 1, a mounting seat 3 is fixedly installed on the left side of the partition plate 2 and the left inner wall of the detection box body 1, a fixing rod 4 is fixedly installed inside the two mounting seats 3, and a movable connecting rod 5 is slidably connected to the outer sides of the two fixing rods 4.

[0023] Among them, limiting grooves are provided on the inner walls of the opposite sides of the two mounting seats 3, and the movable connecting rod 5 is slidably connected to the inner wall of the mounting seat 3 through the limiting groove, so that the movable connecting rod 5 can be limited by the limiting groove when moving, so that the moving state of the movable connecting rod 5 remains stable, and a placing rack 6 is fixedly installed on the opposite sides of the two movable connecting rods 5, and the top and bottom of the movable connecting rod 5 are fixedly installed with a buffer spring 7 sleeved on the outside of the fixed rod 4, and a connecting rack 8 is fixedly installed at the bottom of the placing rack 6. When the connecting rack 8 is vibrated, it shakes up and down through the buffer spring 7, thereby oscillating the test tube.

[0024] Among them, a placing base 9 is fixedly installed on the inner side of the connecting frame 8, and a groove is opened on the top of the placing base 9. A silicone protective pad is arranged inside the placing frame 6, and a mounting hole is opened inside the silicone protective pad, so that the test tube can be placed inside the placing frame 6 to remain stable, and its bottom is in contact with the groove at the top of the placing base 9, thereby realizing double limiting, so that the test tube will not tip over or slide during the shaking process. A micro vibration motor 10 is arranged on the connecting frame 8 and located at the bottom of the placing base 9, and the vibration generated by the micro vibration motor 10 is used to oscillate the sample.

[0025] Among them, a shock-absorbing seat 11 is fixedly installed on the inner bottom wall of the detection box body 1, and a shock-absorbing spring 12 is fixedly installed inside the shock-absorbing seat 11. A support rod 13 extending to the top of the shock-absorbing seat 11 and fixedly connected to the bottom of the connecting frame 8 is fixedly installed on the top of the shock-absorbing spring 12. A first through hole is opened on the top of the shock-absorbing seat 11, and the support rod 13 extends to the top of the shock-absorbing seat 11 through the first through hole, so that the support rod 13 can reduce the vibration of the connecting frame 8 through the first through hole, thereby achieving the stability of the detection box body 1.

[0026] In this embodiment, the auxiliary storage component includes a fixed block 14 fixedly installed on the right side of the partition plate 2 and the right inner wall of the detection box body 1, and a sample storage box 15 is movably placed on the top of the fixed block 14. A limiting plate 16 is arranged inside the sample storage box 15. A plurality of placement holes are opened inside the limiting plate 16, and the placement holes are distributed from small to large, so that sample storage tubes of different specifications can be placed conveniently using the limiting plate 16.

[0027] Among them, a material placement box 17 is movably inserted at the bottom of the fixed block 14, a mounting slide groove is opened at the bottom of the fixed block 14, and a plug-in groove is opened on the front of the detection box body 1. The material placement box 17 extends to the inside of the detection box body 1 through the plug-in groove and is slidably inserted with the mounting slide groove at the bottom of the fixed block 14, so that the material placement box 17 can be easily taken and placed, so that ice cubes or heated items can be placed according to usage requirements, thereby realizing long-term preservation of samples.

[0028] It should be noted that the test kit for multiple detection of tuberculosis drug-resistant genes, through the arrangement of a sample oscillation mechanism and an auxiliary storage component, with the cooperation of various structures on the test kit body 1, can place the sample containing the tuberculosis drug-resistant gene on the storage rack 6, and utilize the vibration generated by the micro-vibration motor 10 to fully oscillate the reagent, thereby helping to improve the accuracy of subsequent test sample data, and according to the sample storage requirements, ice cubes or heated materials can be placed inside the material storage box 17, thereby extending the storage time of the sample, making the use of the sample detection kit more practical and convenient.

[0029] The working principle of the above embodiment is:

[0030] When using the test kit for multiple detection of tuberculosis drug-resistant genes, the box cover is first opened, and then the reagent tube containing the sample is placed in the middle position of the placement rack 6, and the bottom is in contact with the top of the placement base 9, and then the micro-vibration motor 10 is started to drive the placement rack 6 to vibrate, so that the reagent vibrates evenly with the vibration. When it is necessary to store the sample in the test tube, an ice bag or a warming item can be placed in the material placement box 17 according to the storage environment, so that the storage time of the sample is extended, which is more convenient for the use of the sample detection box.

[0031] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0032] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A kit for multiplex detection of tuberculosis drug resistance genes, comprising a detection kit body (1), characterized in that: The detection box body (1) is provided with a sample oscillation mechanism, and the detection box body (1) is provided with an auxiliary storage component; The sample oscillation mechanism comprises a partition plate (2) fixedly mounted inside the detection box body (1); a mounting seat (3) is fixedly mounted on the left side of the partition plate (2) and the left inner wall of the detection box body (1); a fixing rod (4) is fixedly mounted inside the two mounting seats (3); a movable connecting rod (5) is slidably connected to the outer sides of the two fixing rods (4); a placement rack (6) is fixedly mounted on the opposite side of the two movable connecting rods (5); and a buffer spring (7) sleeved on the outer side of the fixing rod (4) is fixedly mounted on the top and bottom of the movable connecting rod (5); A connecting frame (8) is fixedly mounted on the bottom of the placement frame (6), a placement base (9) is fixedly mounted on the inner side of the connecting frame (8), a micro vibration motor (10) is arranged on the connecting frame (8) and is located at the bottom of the placement base (9), a shock absorbing seat (11) is fixedly mounted on the inner bottom wall of the detection box body (1), a shock absorbing spring (12) is fixedly mounted inside the shock absorbing seat (11), and a support rod (13) extending to the top of the shock absorbing seat (11) and fixedly connected to the bottom of the connecting frame (8) is fixedly mounted on the top of the shock absorbing spring (12).

2. A kit for multiplex detection of tuberculosis drug resistance genes according to claim 1, characterized in that: The auxiliary storage component comprises a fixed block (14) fixedly mounted on the right side of the partition plate (2) and the right inner wall of the detection box body (1); a sample storage box (15) is movably placed on the top of the fixed block (14); a limiting plate (16) is arranged inside the sample storage box (15); and a material placement box (17) is movably inserted at the bottom of the fixed block (14).

3. A kit for multiplex detection of tuberculosis drug resistance genes according to claim 1, characterized in that: Limiting grooves are provided on the inner walls of the two mounting seats (3) on opposite sides, and the movable connecting rod (5) is slidably connected to the inner wall of the mounting seat (3) via the limiting grooves.

4. A kit for multiplex detection of tuberculosis drug resistance genes according to claim 1, characterized in that: A groove is provided on the top of the placement base (9), a silicone protective pad is provided inside the placement frame (6), and a mounting hole is provided inside the silicone protective pad.

5. The kit for multiplex detection of tuberculosis drug resistance genes according to claim 1, characterized in that: A first through hole is formed at the top of the shock absorbing seat (11), and the support rod (13) extends through the first through hole to the top of the shock absorbing seat (11).

6. A kit for multiplex detection of tuberculosis drug resistance genes according to claim 2, characterized in that: A plurality of placement holes are provided inside the limiting plate (16), and the placement holes are distributed from small to large.

7. A kit for multiplex detection of tuberculosis drug resistance genes according to claim 2, characterized in that: The bottom of the fixed block (14) is provided with a mounting slot, the front of the detection box body (1) is provided with a plug-in slot, and the material placement box (17) extends through the plug-in slot to the inside of the detection box body (1) and is slidably plugged into the mounting slot at the bottom of the fixed block (14).