Method for preparing high-purity catechin gallate CG
Through high-temperature conversion and liquid chromatography separation technology, the problem of low purity of catechin gallate CG in the existing technology is solved, high-purity preparation is achieved, the cost is reduced and the separation efficiency is improved.
CN105646429AInactive Publication Date: 2016-06-08ZHEJIANG INSTITUTE OF QUALITY SCIENCES
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Patent Information
- Application Number
- CN201610129514.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2016-03-08
- Publication Date
- 2016-06-08
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Technical Problem
It is difficult to effectively prepare high-purity catechin gallate CG monomer compounds with the existing technology, and the cost of raw materials in common methods is high, impurities are introduced, and the purity is low.
Method used
Green tea polyphenols are used as raw materials, and high-purity catechin gallate CG is prepared through high-temperature conversion and rapid preparative liquid chromatography, combined with high-pressure preparative liquid chromatography separation methods to optimize the separation conditions.
Benefits of technology
The high-purity (greater than 99%) preparation of catechin gallate CG is achieved, avoiding the introduction of inorganic salts and heavy metal impurities, reducing production costs, and improving separation efficiency.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention relates to a method for preparing high-purity catechin gallate CG. The method includes: taking a green tea polyphenol sample, and adding a solvent for dissolving; placing a proper amount of a tea polyphenol dissolved sample in an airtight container, and performing high-temperature conversion; taking conversion liquid, adopting quickly-prepared liquid chromatogram for separation, and collecting CG distillate; preparing the distillate into a CG monomeric compound crude product through rotating, evaporating and concentrating; taking a proper amount of the crude product, and adding a solvent for dissolving; utilizing high-pressure-prepared liquid chromatogram to separate and purify the monomeric compound crude product, and collecting CG distillate; preparing the CG distillate into a CG high-purity monomeric compound through rotating, evaporating and concentrating, freeze drying and vacuum drying. A high-temperature conversion method is adopted, so that content of CG in a green tea polyphenol solution is increased.
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