Extraction method of auricularia auricula polysaccharides and preparing method of preparations of auricularia auricula polysaccharides

Abstract

The invention provides an extraction method of auricularia auricula polysaccharides and a preparing method of preparations of auricularia auricula polysaccharides and belongs to the field of biological medicine. The extraction method includes the steps of baking raw material of auricularia auricula, superfine grinding, extracting by adding water, and centrifuging to obtain auricularia auricula polysaccharides. Compared with the prior art, the yield and the .02- clearance rate of the auricularia auricula polysaccharides prepared according to the technical scheme are increased greatly.

Description

technical field

[0001] The invention relates to the field of biomedicine, in particular to a method for extracting polysaccharides from fungus and a preparation method thereof. Background technique

[0002] With the advancement of science and technology and the improvement of living standards, people's pursuit of high-quality life, health and comfort is becoming more and more intense. Fungal polysaccharides are currently the most promising new resource for health food and medicine. Scientific experiments have shown that fungal polysaccharides have anti-tumor activity, strong inhibitory effect on cancer cells, and play an important role in immune regulation, lowering blood pressure, lowering blood fat, and antithrombotic. At present, the research on the relationship between the structure, properties and pharmacodynamics of polysaccharides has become one of the most active research fields in life sciences. The main active ingredient in black fungus - black fungus polysacchar...

Examples

Embodiment 1

[0026] Bake 500g of dry black fungus raw material at a temperature of 75°C for 180min, then ultrafinely pulverize it to a particle size of 100 mesh, add water 40 times the weight ratio and soak for 30min, extract at a temperature of 100°C, extract for 1h, and centrifuge the extract at 5000rpm , vacuum-dried to obtain 52.8g of fungus polysaccharide, which was crushed into fine powder, added an appropriate amount of auxiliary materials such as starch and dextrin, mixed evenly, made into granules, and packed into hard capsules to obtain 1000 capsules.

Embodiment 2

[0028] Bake 800g of dried black fungus raw material at a temperature of 95°C for 30 minutes, then ultrafinely pulverize it to a particle size of 200 mesh, add water 30 times the weight ratio and soak for 90 minutes, extract at a temperature of 95°C, extract for 3 hours, and centrifuge the extract at 3000rpm , vacuum-dried to obtain 72.2g of fungus polysaccharide, crushed into fine powder, added appropriate amount of starch, dextrin and other auxiliary materials, mixed, wet granulated, granulated after drying, packaged to obtain 1000g granules.

Embodiment 3

[0030] Bake 650g of dried black fungus raw material at a temperature of 85°C for 60 minutes, then ultrafinely pulverize it to a particle size of 160 mesh, add water 35 times the weight ratio and soak for 60 minutes, extract at a temperature of 98°C, extract for 2 hours, and centrifuge the extract at 4000rpm , vacuum-dried to obtain 78.1g of fungus polysaccharide, crushed into fine powder, added appropriate amount of starch, dextrin and other auxiliary materials, mixed evenly, made into granules, and pressed into tablets to obtain 1000 preparations.

[0031] Example 1

[0032] 650g of dried black fungus raw materials were ultrafinely pulverized to a particle size of 160 mesh, soaked in 35 times of water by weight for 60 minutes, extracted at 98°C for 2 hours, centrifuged at 4000rpm, and dried in vacuum to obtain 35.9g of fungus polysaccharides. Crush it into fine powder, add appropriate amount of auxiliary materials such as starch and dextrin, mix well, make granules, and press...

technical field

[0001] The invention relates to the field of biomedicine, in particular to a method for extracting polysaccharides from fungus and a preparation method thereof. Background technique

[0002] With the advancement of science and technology and the improvement of living standards, people's pursuit of high-quality life, health and comfort is becoming more and more intense. Fungal polysaccharides are currently the most promising new resource for health food and medicine. Scientific experiments have shown that fungal polysaccharides have anti-tumor activity, strong inhibitory effect on cancer cells, and play an important role in immune regulation, lowering blood pressure, lowering blood fat, and antithrombotic. At present, the research on the relationship between the structure, properties and pharmacodynamics of polysaccharides has become one of the most active research fields in life sciences. The main active ingredient in black fungus - black fungus polysacchar...

Examples

Embodiment 1

[0026] Bake 500g of dry black fungus raw material at a temperature of 75°C for 180min, then ultrafinely pulverize it to a particle size of 100 mesh, add water 40 times the weight ratio and soak for 30min, extract at a temperature of 100°C, extract for 1h, and centrifuge the extract at 5000rpm , vacuum-dried to obtain 52.8g of fungus polysaccharide, which was crushed into fine powder, added an appropriate amount of auxiliary materials such as starch and dextrin, mixed evenly, made into granules, and packed into hard capsules to obtain 1000 capsules.

Embodiment 2

[0028] Bake 800g of dried black fungus raw material at a temperature of 95°C for 30 minutes, then ultrafinely pulverize it to a particle size of 200 mesh, add water 30 times the weight ratio and soak for 90 minutes, extract at a temperature of 95°C, extract for 3 hours, and centrifuge the extract at 3000rpm , vacuum-dried to obtain 72.2g of fungus polysaccharide, crushed into fine powder, added appropriate amount of starch, dextrin and other auxiliary materials, mixed, wet granulated, granulated after drying, packaged to obtain 1000g granules.

Embodiment 3

[0030] Bake 650g of dried black fungus raw material at a temperature of 85°C for 60 minutes, then ultrafinely pulverize it to a particle size of 160 mesh, add water 35 times the weight ratio and soak for 60 minutes, extract at a temperature of 98°C, extract for 2 hours, and centrifuge the extract at 4000rpm , vacuum-dried to obtain 78.1g of fungus polysaccharide, crushed into fine powder, added appropriate amount of starch, dextrin and other auxiliary materials, mixed evenly, made into granules, and pressed into tablets to obtain 1000 preparations.

[0031] Example 1

[0032] 650g of dried black fungus raw materials were ultrafinely pulverized to a particle size of 160 mesh, soaked in 35 times of water by weight for 60 minutes, extracted at 98°C for 2 hours, centrifuged at 4000rpm, and dried in vacuum to obtain 35.9g of fungus polysaccharides. Crush it into fine powder, add appropriate amount of auxiliary materials such as starch and dextrin, mix well, make granules, and press...

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