Filter assembly and thrombus aspiration assembly for pulmonary embolism thrombus removal

Abstract

The present invention relates to the technical field of medical devices, and discloses a filter assembly and a thrombus aspiration assembly for removing pulmonary embolism thrombi. The filter assembly comprises: a thrombus crushing filter that can be radially elastically expanded and coaxially arranged, a first isolation filter and a second isolation filter; the thrombus crushing filter is arranged between the first isolation filter and the second isolation filter. The thrombus aspiration assembly comprises: a thrombus aspiration tube, a thrombus output tube, a thrombus aspirator and a connecting seat with a hollow channel; the hollow channel is used to pass through the filter assembly as described above after being stored; the thrombus aspiration tube is provided at the front end of the connecting seat, and a flexible sealing valve is provided at the rear end opening of the connecting seat, the inner end of the thrombus output tube is connected to the side of the connecting seat, and the outer end of the thrombus output tube is connected to the thrombus aspirator. This embodiment can effectively remove large pulmonary embolism thrombi, reduce the complexity of surgery, and shorten the operation time.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a filter assembly and a thrombus suction assembly for removing pulmonary embolism thrombus. Background Art

[0002] Acute pulmonary embolism (PE) is a common cardiovascular disease. It is a clinical and pathophysiological syndrome of pulmonary circulation disorder caused by endogenous or exogenous emboli blocking the pulmonary artery. It is often caused by the detachment of thrombi from deep vein thrombosis in the lower extremities. It has a high mortality rate and seriously endangers the health and quality of life of patients. Pulmonary thromboembolism is the most common type of acute PE, and deep vein thrombosis is the main source of thrombi that cause pulmonary thromboembolism.

[0003] Acute pulmonary embolism is a rapidly developing pulmonary circulation disorder. The main symptoms are dyspnea and chest tightness, and even death. Clinical studies have shown that the mortality rate of pulmonary embolism is very high. The main method of treating pulmonary embolism is surgery. Timely treatment after the onset of the disease can avoid recurrence and death of the patient.

[0004] Traditional surgical methods for treating pulmonary embolism mainly include thrombectomy and pulmonary endarterectomy, which are very traumatic. At present, endovascular treatment has become an effective and important treatment for acute pulmonary embolism. Common treatment methods now mainly include guidewire catheter thrombus fragmentation, thrombus aspiration, intra-catheter thrombolysis and other surgical treatments. When using existing instruments alone to remove thrombi, the removal effect of large pulmonary artery thrombi is not ideal, and when using multiple surgical methods, the surgical operation is complicated, the operation time is long, and the cost is high. Summary of the invention

[0005] The purpose of the present invention is to provide a filter assembly and a thrombus suction assembly for removing pulmonary embolism thrombus, which can effectively remove large pulmonary embolism thrombus, reduce surgical complexity and shorten surgical time.

[0006] In order to solve the above technical problems, an embodiment of the present invention provides a filter assembly for removing pulmonary embolism thrombus, comprising:

[0007] A thrombus-breaking filter, a first isolation filter and a second isolation filter which are radially elastically expandable and coaxially arranged; the thrombus-breaking filter is arranged between the first isolation filter and the second isolation filter.

[0008] The embodiment of the present invention also provides a thrombus aspiration assembly for removing pulmonary embolism thrombus, comprising: a thrombus aspiration tube, a thrombus output tube, a thrombus aspirator and a connecting seat;

[0009] The inner end of the thrombus aspiration tube is connected to the connection seat, and the thrombus aspiration tube and the connection seat form a channel, and the channel is used to penetrate the stored filter assembly as described above;

[0010] A flexible sealing valve is provided at the channel opening of the connecting seat, the inner end of the thrombus output tube is connected to the side of the connecting seat, and the outer end of the thrombus output tube is connected to the thrombus aspirator.

[0011] The filter assembly for removing pulmonary embolism thrombus provided in an embodiment of the present invention comprises a thrombus crushing filter that can be radially elastically expanded and coaxially arranged, a first isolation filter and a second isolation filter. The thrombus crushing filter is arranged between the first isolation filter and the second isolation filter. Before use, the filter assembly can be stored in a filter recovery tube. When the filter recovery tube is withdrawn, the filter assembly will radially expand and automatically open, and effective thrombus crushing can be achieved in this process, so that large pulmonary artery thrombi can be crushed. In addition, since the first isolation filter and the second isolation filter are respectively arranged at both ends of the thrombus crushing filter, the crushed large thrombus can be filtered and intercepted, and the smaller thrombus after crushing can be prevented from escaping and blocking the distal blood vessels. At the same time, the thrombus suction assembly provided in this embodiment can be used in conjunction with the filter assembly. The filter assembly in the stored state can be inserted through the channel of the thrombus suction assembly and pushed to the thrombus breaking position, and the broken thrombus can be sucked out through the thrombus suction tube, the thrombus output tube and the thrombus suction device. On the basis that the filter assembly of the present embodiment can effectively break up large pieces of thrombus, the thrombus removal effect can be greatly improved by using the thrombus suction assembly for suction. Therefore, the present embodiment can effectively remove large pieces of pulmonary artery thrombus, reduce the complexity of the operation, and shorten the operation time.

[0012] As an embodiment, the first isolation filter and the second isolation filter are both ellipsoidal; the thrombus fragmentation filter is lantern-shaped.

[0013] As an embodiment, the thrombus fragmentation filter, the first isolation filter, and the second isolation filter are all woven from elastic fine metal wires.

[0014] As an embodiment, the meshes of the first isolation filter and the second isolation filter are both in a diamond shape or approximately in a diamond shape.

[0015] As an embodiment, both ends of the thrombus fragmentation filter, both ends of the first isolation filter, and both ends of the second isolation filter are provided with developing points.

[0016] As an embodiment, the filter assembly further includes: a filter recovery device;

[0017] The filter recovery device comprises: a fixedly connected filter recovery pipe and a recovery pipe seat;

[0018] The thrombus fragmentation filter, the first isolation filter and the second isolation filter are all housed in the filter recovery tube.

[0019] As an embodiment, the outer end of the first isolation filter is provided with a pointed soft head, the inner end of the second isolation filter is connected to the injection liner, the other end of the injection liner is provided with a injection pipe seat, and the side of the injection pipe seat is provided with a drug injection joint.

[0020] As an embodiment, a plurality of guide grooves parallel to the axis and distributed along the circumference are provided between the two ends of the perfusion liner, and a plurality of micro holes connected to the guide grooves are provided on the outer side surface of the front end of the perfusion liner.

[0021] As an embodiment, a valve is provided at the connection between the thrombus aspirator and the thrombus output tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. It can be understood that the drawings in the following description are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0023] Figure 1 A schematic diagram of the structure of the filter assembly of an embodiment of the present application;

[0024] Figure 2 A schematic diagram of the structure of an isolation filter provided in an embodiment;

[0025] Figure 3 A schematic diagram of the structure of a thrombus fragmentation filter provided in an embodiment;

[0026] Figure 4 A schematic diagram of the connection structure between a grouting liner and a grouting pipe seat provided in an embodiment;

[0027] Figure 5 A schematic diagram of a partial structure of a perfusion liner provided in an embodiment;

[0028] Figure 6 A schematic diagram of the structure of a thrombus aspiration assembly provided in one embodiment;

[0029] Figure 7 A schematic diagram of the structure of a flexible sealing valve provided by an embodiment;

[0030] Figure 8 A schematic diagram of the use status of a filter assembly and a thrombus aspiration assembly provided in an embodiment;

[0031] Fig. 9A schematic diagram of the retracted state of a filter assembly provided in an embodiment.

[0032] In the figure: filter assembly 1, first isolation filter 11, thrombus crushing filter 12, first isolation filter 13, developing point 14, mesh 15, arc portion 16, filter recovery tube 17, recovery tube seat 18, perfusion liner 21, perfusion tube seat 22, injection connector 23, pointed soft head 24, micropore 211, guide groove 212, connecting tube 31, thrombus suction tube 32, flexible sealing valve 33, thrombus output tube 34, valve 35, thrombus suction device 36, puncture inner core 41, inner core connecting seat 42. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical scheme and advantages of the present invention clearer, the following will be described in detail with reference to the accompanying drawings. However, it will be appreciated by those skilled in the art that in the various embodiments of the present invention, many technical details are provided in order to enable the reader to better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical scheme claimed for protection in the claims of the present application can be implemented.

[0034] The present application embodiment provides a filter assembly for removing pulmonary embolism thrombus. Figures 1 to 3 As shown, the filter assembly 1 includes: a thrombus-breaking filter 12 that can elastically expand radially and is coaxially arranged, a first isolation filter 11 and a second isolation filter 13; the thrombus-breaking filter 12 is arranged between the first isolation filter 11 and the second isolation filter 13.

[0035] The filter assembly of this embodiment can be stored in the filter recovery device before use. During use, it is pushed to the location of the pulmonary embolism thrombus, and the large thrombus is broken by the thrombus breaking filter, and the first isolation filter and the second isolation filter filter respectively filter and intercept the broken small thrombus from both sides of the thrombus breaking filter to prevent the broken smaller thrombus from escaping and blocking the distal blood vessels. Therefore, the use of the filter assembly of this embodiment in conjunction with other suitable pulmonary embolism thrombus removal devices can more effectively remove large pulmonary embolism thrombi, while reducing the complexity of the operation and shortening the operation time.

[0036] Optionally, the thrombus crushing filter 12 is lantern-shaped, and the lantern-shaped thrombus crushing filter 12 has an arc-shaped portion 16 structure, which can squeeze and tear the thrombus at the large thrombus in the pulmonary artery without damaging the blood vessel, and the lantern-shaped thrombus crushing filter 12 has a strong supporting force performance, which can squeeze and tear the thrombus at the large thrombus. At the same time, the lantern-shaped thrombus crushing filter 12 applies a dragging force to the thrombus when it is opened, and mechanically stretches the thrombus, thereby achieving the purpose of crushing the large thrombus in the pulmonary artery.

[0037] The first isolation filter 11 and the second isolation filter 13 are both ellipsoidal in shape, so as to better filter and intercept broken thrombi.

[0038] Optionally, the thrombus-breaking filter screen 12, the first isolation filter screen 11, and the second isolation filter screen 13 are all woven from thin elastic metal wires. This embodiment does not impose any specific restrictions on this, and the filter screen assembly can also be made by other processing techniques.

[0039] Optionally, in this embodiment, the meshes 15 of the first isolation filter 11 and the second isolation filter 13 are both rhombus-shaped or approximately rhombus-shaped, and are regularly arranged on the first isolation filter 11 and the second isolation filter 13, so that the broken thrombus can be better filtered and intercepted. This embodiment does not specifically limit the mesh structure and arrangement of the first isolation filter 11 and the second isolation filter. It should be understood that in some applications, the mesh structure can also be a triangle or other mesh structure with good filtering performance.

[0040] Optionally, both ends of the thrombus fragmentation filter 12, both ends of the first isolation filter 11, and both ends of the second isolation filter 13 are provided with developing points 14. This can better assist in accurately locating the position of large thrombi. This embodiment does not impose any specific restrictions on the number and location of the developing points 14, as long as they are conducive to accurately locating the position of the thrombus.

[0041] Optionally, the filter assembly 1 may further include: a filter recovery device; the filter recovery device includes: a fixedly connected filter recovery pipe and a recovery pipe seat; the thrombus breaking filter 12, the first isolation filter 11 and the second isolation filter 13 are all received in the filter recovery pipe. The release and recovery methods of the thrombus breaking filter 12, the first isolation filter 11 and the second isolation filter 13 are described below.

[0042] In some applications, such as Figure 4~Figure 5 As shown, the outer end of the first isolation filter 11 is provided with a sharp soft head 24, the inner end of the second isolation filter 13 is connected to the perfusion liner 21, the other end of the perfusion liner 21 is provided with a perfusion pipe seat 22, and the side of the perfusion pipe seat 22 is provided with a drug injection joint 23. The sharp soft head 24 will not damage the blood vessel during the process of pushing the filter assembly to the thrombus position, and is conducive to the advancement of the filter assembly.

[0043] Optionally, a plurality of guide grooves 212 parallel to the axis and distributed along the circumference are provided between the two ends of the perfusion liner 21, and a plurality of micropores 211 connected to the guide grooves are provided on the outer side surface of the front end of the perfusion liner 21. The perfusion liner 21 and the perfusion tube seat 22 can not only be used to push the filter assembly to the thrombus position, but also to withdraw the filter assembly, and thrombolytic drugs can also be injected through the perfusion liner 23 to prevent foreign body invasion from causing coagulation and thrombus formation. This embodiment does not specifically limit the pushing and withdrawing device of the filter assembly. In some applications, other instruments can also be used to achieve the pushing and withdrawing of the filter assembly.

[0044] The filter assembly of this embodiment can be used in conjunction with other pulmonary embolism thrombus removal devices. It can remove pulmonary embolism thrombi during the pulmonary embolism thrombus removal process, and filter and intercept broken thrombi to prevent them from escaping and clogging distal blood vessels, thereby achieving effective removal of large pulmonary artery thrombi, reducing surgical complexity, and shortening surgical time.

[0045] The present application embodiment provides a thrombus aspiration assembly for removing pulmonary embolism thrombus, such as Figure 6 As shown, the thrombus suction assembly 3 comprises: a thrombus suction tube 32, a thrombus output tube 34, a thrombus suction device 36 and a connecting seat 31; the inner end of the thrombus suction tube 32 is connected to the connecting seat 31, and the thrombus suction tube 32 and the connecting seat 31 form a channel, and the channel is used to penetrate the stored filter assembly as described in the above embodiment; a flexible sealing valve 33 is provided at the channel opening of the connecting seat 31, the inner end of the thrombus output tube 34 is connected to the side of the connecting seat 31, and the outer end of the thrombus output tube 34 is connected to the thrombus suction device 36. Optionally, a valve 35 is provided at the connection between the thrombus suction device 36 and the thrombus output tube 34.

[0046] In this embodiment, there is a large gap between the thrombus aspiration tube 32 and the filter recovery tube loaded with the filter assembly, forming a guide gap between the two, and the thrombus output tube 34 is connected to the guide gap, so that the thrombus in the thrombus aspiration tube 32 can be aspirated by the thrombus aspirator 36.

[0047] like Figure 7 As shown, in this embodiment, the flexible sealing valve 33 is made of soft medical material, and the flexible sealing valve 33 has a closed sealing structure 331 .

[0048] Optionally, the thrombus output tube 34 and the connecting seat 31 are detachably connected, but not limited to this, and the two can also be fixedly connected.

[0049] In conjunction with the accompanying drawings, the method and steps for using the filter assembly and the thrombus aspiration assembly in the embodiment of the present application are as follows:

[0050] In the surgical treatment of acute pulmonary embolism, an instrument intervention channel is established in the femoral vein through a puncture needle, guide wire, catheter and small puncture sheath. The catheter is introduced into the central pulmonary artery through the intravascular intervention channel technology, and then selective main pulmonary artery angiography, pulmonary artery detection, and digital subtraction pulmonary angiography are performed to determine the location of the pulmonary artery thrombus in the blood vessel. The angiography catheter is replaced with a guide wire (the guide wire is introduced and then withdrawn from the catheter). Figure 6 The combined replacement catheter of the thrombus aspiration assembly, the puncture inner core 41, the inner core connection seat 42, etc., the puncture inner core 41 has a pointed structure, which can be easily punctured into the blood vessel in cooperation with the thrombus aspiration tube 32, and then the puncture inner core 41 is withdrawn through the inner core connection seat 42, and the thrombus aspiration assembly is retained, wherein the puncture inner core 41 and the inner core connection seat 42 may not belong to the thrombus aspiration assembly. Thereafter, the filter assembly loaded in the filter recovery device is pushed to the proximal occluded part of the pulmonary artery or the part with the largest thrombus content, such as Figure 8 As shown, the filter assembly with a pointed soft head 24 and the perfusion liner 21 is pushed to the part with large thrombus content. During the pushing process, the filter assembly is loaded in the filter recovery tube 17, and can be positioned through the developing point 14 on the filter assembly 1 while pushing. When it is determined that the thrombus crushing filter 12 in the filter assembly 1 is located at the position with the maximum thrombus content, the pushing is stopped. Then hold the perfusion tube seat 22, hold the perfusion liner 21, withdraw the filter recovery tube 17 through the recovery tube seat 18, release the filter assembly 1, and fully expand the filter assembly. At this time, the thrombus crushing filter 12 is fully embedded in and breaks up large pieces of thrombus. Connect the thrombus output tube 34 to the connecting seat 31, and use the thrombus aspirator 36 to aspirate the thrombus in the thrombus aspiration tube 32. Then, as Fig. 9 As shown, the recovery tube seat 18 can be held, and the perfusion tube seat 22 can be slowly pulled back to pull the broken thrombus of the filter assembly 1 into the thrombus suction tube 32 for continued suction, until the filter assembly 1 is completely withdrawn into the filter recovery tube 17. At this time, a part of the thrombus is collected in the filter recovery tube, and is withdrawn from the body together with the filter recovery tube 17 and the thrombus suction assembly to complete the thrombus removal. It should be noted that in actual operation, the thrombus aspirator 36 can be used at any time to aspirate the thrombus in the thrombus suction tube 32 to ensure more thorough thrombus removal.

[0051] The thrombus aspiration component of this embodiment is used in conjunction with the filter component. The filter component can break up large pieces of thrombus (thrombus that is difficult to be extracted by the thrombus aspiration component alone), and can filter and intercept the broken thrombus to prevent it from escaping and blocking the distal blood vessels. At the same time, most of the thrombus can be recovered into the filter recovery tube and withdrawn from the body, and the thrombus aspiration component can timely aspirate the broken part of the thrombus. Thus, the large pulmonary artery thrombus can be effectively removed, the complexity of the operation can be reduced, and the operation time can be shortened.

[0052] Although this article only describes the use of the filter assembly in conjunction with the thrombus aspiration assembly, it should be understood that the filter assembly disclosed in the embodiment of the present application can also be used in conjunction with other suitable pulmonary embolism thrombus removal devices.

[0053] Those skilled in the art will appreciate that the above-mentioned embodiments are specific examples for implementing the present invention, and in actual applications, various changes may be made thereto in form and detail without departing from the spirit and scope of the present invention.

Claims

1. A thrombus removal device for pulmonary embolism, characterized in that: include: Filter assembly and thrombus aspiration assembly; The filter assembly comprises: a thrombus-breaking filter that can be radially elastically expanded and coaxially arranged, a first isolation filter and a second isolation filter; the thrombus-breaking filter is arranged between the first isolation filter and the second isolation filter; The first isolation filter and the second isolation filter are both ellipsoidal; the thrombus crushing filter is lantern-shaped; The meshes of the first isolation filter screen and the second isolation filter screen are both rhombus-shaped; The filter assembly also includes: a fixedly connected filter recovery pipe and a recovery pipe seat; The thrombus fragmentation filter, the first isolation filter and the second isolation filter are all received in the filter recovery tube; The outer end of the first isolation filter is provided with a pointed soft head, the inner end of the second isolation filter is connected to the injection liner, the other end of the injection liner is provided with an injection pipe seat, and the side of the injection pipe seat is provided with a drug injection joint; A plurality of guide grooves parallel to the axis and distributed along the circumference are provided between the two ends of the perfusion liner, and a plurality of micropores connected to the guide grooves are provided on the outer side surface of the front end of the perfusion liner. The perfusion liner and the perfusion tube seat are used to push the filter assembly to the thrombus position and withdraw the filter assembly, and are also used to inject thrombolytic drugs; The thrombus aspiration assembly comprises: a thrombus aspiration tube, a thrombus output tube, a thrombus aspirator and a connecting seat; The inner end of the thrombus aspiration tube is connected to the connection seat, and the thrombus aspiration tube and the connection seat form a channel, and the channel is used to penetrate the filter assembly after being stored; A flexible sealing valve is provided at the channel opening of the connecting seat, the inner end of the thrombus output tube is connected to the side of the connecting seat, and the outer end of the thrombus output tube is connected to the thrombus aspirator.

2. The thrombus removal device for pulmonary embolism according to claim 1, characterized in that: The thrombus-breaking filter, the first isolation filter and the second isolation filter are all woven from elastic fine metal wires.

3. The thrombus removal device for pulmonary embolism according to claim 1, characterized in that: Both ends of the thrombus-breaking filter, both ends of the first isolation filter, and both ends of the second isolation filter are provided with developing points.

4. The thrombus removal device for pulmonary embolism according to claim 1, characterized in that: A valve is provided at the connection between the thrombus aspirator and the thrombus output tube.

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