A human exhaled breath sampling device based on liquid phase collection

By using a liquid-phase-based human exhaled breath sampling device, which utilizes components such as a disposable inhalation mask and an inhalation pump, efficient virus collection is achieved. This solves the problems of long collection time and high infection risk in existing technologies, improves the efficiency and accuracy of respiratory sample collection, and reduces the infection risk for medical staff.

CN111317514BActive Publication Date: 2025-01-10青岛国际旅行卫生保健中心
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Patent Information

Application Number
CN202010312747.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-04-20
Publication Date
2025-01-10
Estimated Expiration
2040-04-20

AI Technical Summary

Technical Problem

Existing methods for collecting respiratory samples are time-consuming, can cause discomfort to the subjects, and pose a high risk of infection for medical staff, making it difficult to guarantee the effectiveness of epidemic control.

Method used

The exhaled breath sampling device based on liquid phase acquisition uses a disposable inhalation mask, inhalation pump, buffer tank, gas flow meter and enrichment component, combined with automatic sample dispensing component and turbine fan stirring, to achieve efficient virus collection and reduce the risk of infection for operators.

Benefits of technology

It improves the efficiency and accuracy of respiratory sample collection, reduces the risk of viral infection for healthcare workers, and is suitable for rapid and efficient virus detection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention belongs to the field of respiratory sample collection equipment, specifically a human exhaled breath sampling equipment based on liquid phase collection, including a temporary storage box; a discharge pipe is opened at the lower left end of the temporary storage box, and the discharge rate of the discharge pipe is controlled by an automatic sample discharge component; a gas sample collection bag is installed on the end part of the discharge pipe, and a restriction box is provided on the outer side of the gas sample collection bag; an air inlet port is installed at the upper end of the temporary storage box, and the air inlet port is connected to an enrichment component through an air pipe, and the enrichment component is connected to a gas flow meter, a buffer tank and an air suction pump in sequence through the air pipe, and a disposable blowing hood is installed at the upper end of the air suction pump; in the process of collecting respiratory samples of incoming personnel, the human exhaled breath sampling equipment based on liquid phase collection, the incoming personnel blow air through the disposable blowing hood, and the blown gas samples pass through the air suction pump, the buffer tank, the gas flow meter and the enrichment component in sequence, and are finally transported to the inside of the temporary storage box through the air pipe, and the viruses in the gas samples adhere to the virus collection liquid, and the collection efficiency is high.
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Description

Technical Field

[0001] The invention relates to the field of respiratory sample collection equipment, in particular to a human exhaled breath sampling equipment based on liquid phase collection. Background Art

[0002] When respiratory diseases such as the new coronavirus occur, respiratory samples need to be collected from people entering and leaving the country at border ports. The main methods for collecting samples for respiratory diseases include throat swabs, bronchoalveolar lavage, nasopharyngeal aspirates or sputum specimens. These methods are time-consuming and can easily cause discomfort to the subjects of the collection, and can easily cause passive infection to the medical staff performing the collection operations. In addition, when influenza epidemics or sudden biological events occur, the number of infected people surges. Due to the limitations of the entry and exit environment conditions, customs health quarantine personnel can only screen for diseases by strengthening epidemiological history inquiries and clinical symptom monitoring. The epidemic control effect is difficult to guarantee, and there is a certain degree of subjective blindness.

[0003] In view of the problems in the above-mentioned background technology, the present invention aims to provide a human exhaled breath sampling device based on liquid phase collection. Summary of the invention

[0004] The purpose of the present invention is to provide a human exhaled breath sampling device based on liquid phase collection, which not only has a high sample collection efficiency, but also has a large respiratory sample collection density and high accuracy; in addition, the risk of medical staff being infected with the virus during the collection process is greatly reduced.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A human exhaled breath sampling device based on liquid phase collection, comprising: a temporary storage box, wherein liquid inlets are provided on the left and right sides of the upper end of the temporary storage box, and virus collection liquid (i.e., liquid adsorbent) is put into the temporary storage box through the liquid inlets; a discharge pipe is provided at the lower left end of the temporary storage box, and the discharge rate of the discharge pipe is controlled by an automatic sample discharge component; a gas sample collection bag is installed on the end portion of the discharge pipe, and a restriction box is provided on the outer side of the gas sample collection bag; an air inlet port is installed on the upper end of the temporary storage box, and the air inlet port is connected to an enrichment component through an air pipe, and the enrichment component is connected to a gas flow meter, a buffer tank and an air pump in sequence through the air pipe, and a disposable blowing hood is installed on the upper end of the air pump.

[0007] Compared with the prior art, the present invention has the following beneficial effects:

[0008] In the process of collecting respiratory samples from inbound personnel, the inbound personnel blow air through a disposable blowing mask, and the blown gas samples pass through the suction pump, buffer tank, gas flow meter and enrichment component in sequence, and are finally transported to the inside of the temporary storage box through the trachea. The viruses in the gas sample adhere to the virus collection liquid, and finally the automatic sample discharging component is turned on to make the mixed virus sample in the temporary storage box enter the gas sample collection bag inside the restriction box together with the virus collection liquid; after testing an inbound person, the gas sample collection bag is removed and replaced, and the disposable blowing mask is replaced for the next person to use, and the collection efficiency is high;

[0009] In addition, in order to increase the number of viruses collected in respiratory samples, the enrichment component usually heats the respiratory samples to a certain temperature; and when the respiratory samples pass through the enrichment component and enter the temporary storage box, the high-pressure airflow generated will impact the rotation of the turbofan, so that the viruses in the respiratory samples are fully mixed and stirred with the virus collection liquid inside the temporary storage box, thereby expanding the density range of virus adhesion;

[0010] More importantly, the automatic sample discharging component set up by electromagnetic induction eliminates the need for the operator to manually open and close the discharging pipe, reducing the risk of the operator being infected with the virus. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 It is a schematic diagram of the structure of a human exhaled breath sampling device based on liquid phase collection according to an embodiment of the present invention.

[0012] Figure 2 This is a schematic diagram of the structure of an enrichment component of a human exhaled breath sampling device based on liquid phase collection in an embodiment of the present invention.

[0013] Figure 3 This is a schematic diagram of the structure of an automatic sampling component of a human exhaled breath sampling device based on liquid phase collection in an embodiment of the present invention.

[0014] In the figure: 1-gas sample collection bag, 2-automatic sample discharging component, 3-turbofan, 4-liquid inlet, 5-temporary storage box, 6-air inlet port, 7-trachea, 8-enrichment component, 9-gas flow meter, 10-buffer tank, 11-suction pump, 12-disposable blowing hood, 13-enrichment box, 14-enrichment tube, 15-resistance wire, 16-temperature probe, 17-cavity, 18-refrigeration plate, 19-suction fan, 20-motor, 21-valve, 22-movable rod, 23-compression spring, 24-magnetic induction coil, 25-conductive column, 26-sleeve. DETAILED DESCRIPTION

[0015] The technical solution of the present invention is further described in detail below in conjunction with specific implementation methods.

[0016] Example 1

[0017] See also Figure 1 In Embodiment 1 of the present invention, a human exhaled breath sampling device based on liquid phase collection comprises: a temporary storage box 5, wherein liquid inlets 4 are provided on the left and right sides of the upper end of the temporary storage box 5, and virus collection liquid (i.e., liquid adsorbent) is put into the temporary storage box 5 through the liquid inlet 4; a discharge pipe is provided at the lower left end of the temporary storage box 5, and the discharge rate of the discharge pipe is controlled by an automatic sample discharge component 2; a gas sample collection bag 1 is installed on the end portion of the discharge pipe, and a restriction box is provided on the outer side of the gas sample collection bag 1; an air inlet port 6 is installed on the upper end of the temporary storage box 5, and the air inlet port 6 is connected to an enrichment component 8 through an air pipe 7, and the enrichment component 8 is connected to a gas flow meter 9, a buffer tank 10 and an air pump 11 in sequence through the air pipe 7, and a disposable blowing hood 12 is installed on the upper end of the air pump 11;

[0018] When collecting respiratory samples from incoming personnel, the virus collection liquid is first put into the temporary storage box 5 through the liquid inlet 4 for temporary storage, then the suction pump 11 is started, and the incoming personnel blow air through the disposable blowing hood 12. The blown gas sample passes through the suction pump 11, the buffer tank 10, the gas flow meter 9 and the enrichment component 8 in turn, and is finally transported to the temporary storage box 5 through the air pipe 7. The virus in the gas sample adheres to the virus collection liquid. Finally, the automatic sample discharge component 2 is turned on to make the mixed virus sample in the temporary storage box 5 enter the gas sample collection bag 1 inside the restriction box together with the virus collection liquid; after testing an incoming person, the gas sample collection bag 1 is removed and replaced, and the disposable blowing hood 12 is replaced for the next person to use; in addition, in order to increase the number of viruses collected in the respiratory sample, the enrichment component 8 usually heats the respiratory sample to a certain temperature.

[0019] Furthermore, a turbofan 3 is hingedly installed inside the temporary storage box 5. When the respiratory sample enters the temporary storage box 5 through the enrichment component 8, the generated high-pressure airflow will impact the turbofan 3 to rotate, so that the virus in the respiratory sample and the virus collection liquid inside the temporary storage box 5 are fully mixed and stirred, thereby expanding the density range of virus adhesion.

[0020] Example 2

[0021] See also Figure 2 Further, the enrichment assembly 8 includes an enrichment box 13, the interior of the enrichment box 13 is a cavity 17, the left and right sides of the cavity 17 are connected to the air pipe 7 at the same time, the air pipe 7 on the left side is connected to the air pipe 7 on the right side through an enrichment pipe 14, the enrichment pipe 14 is made of metal material, a resistance wire 15 is provided on the surface of the enrichment pipe 14, and a temperature probe 16 is installed inside the enrichment pipe 14;

[0022] When the respiratory sample enters the cavity 17 through the trachea 7, the diameter of the enrichment tube 14 in the cavity 17 is smaller than that of the trachea 7, and the respiratory sample is enriched in the enrichment tube 14. The temperature of the respiratory sample in the enrichment tube 14 is detected by the temperature probe 16. If the temperature is too low, the resistance wire 15 is energized to heat the enrichment tube 14, so that the respiratory sample in the enrichment tube 14 expands to a suitable temperature.

[0023] Specifically, the upper end of the enrichment box 13 is connected to the heat dissipation box, and a heat dissipation component is installed inside the heat dissipation box. A cooling fin 18 is installed inside the pipeline connecting the heat dissipation box and the enrichment box 13. There are two cooling fins 18, and both surfaces of the two cooling fins 18 are provided with through holes.

[0024] Furthermore, the heat dissipation assembly includes a suction fan 19 and a motor 20, and the suction fan 19 is mounted on the output shaft of the motor 20;

[0025] When the temperature probe 16 detects that the temperature of the respiratory sample inside the enrichment tube 14 is too high, the motor 20 is started, and the output shaft of the motor 20 causes the suction fan 19 to rotate to generate negative pressure, sucking out the hot air inside the cavity 17 through the cooling fins 18, and cooling the respiratory sample inside the enrichment tube 14;

[0026] The remaining structural parts of Example 2 are the same as those of Example 1.

[0027] Example 3

[0028] See also Figure 3 Further, the automatic sample discharging component 2 includes a valve 21, a movable rod 22 and a sleeve 26, the valve 21 is movably installed inside the discharging pipe, the upper end of the valve 21 is provided with a movable rod 22, the upper end of the movable rod 22 is movably installed inside the sleeve 26, and the sleeve 26 is arranged outside the discharging pipe;

[0029] Specifically, the movable rod 22 is provided with a magnetic block on the part inside the sleeve 26, and a compression spring 23 is provided on the part between the magnetic block and the inner wall of the sleeve 26; a conductive column 25 is provided on the inner wall of the top end of the sleeve 26, and a magnetic induction coil 24 is installed on the outer side of the conductive column 25;

[0030] When the discharge pipe needs to be opened for unloading, the conductive column 25 is powered on, and the conductive column 25 generates the same electromagnetic field as the magnetic block through the magnetic induction coil 24 arranged on the surface, and like charges repel each other, pushing the valve 21 at the lower end of the movable rod 22 to move downward to block the inside of the discharge pipe; when the discharge pipe needs to be opened, the direction of the current connected to the conductive column 25 is changed, so that the magnetic induction coil 24 generates an electromagnetic field opposite to that of the magnetic block, and opposite charges attract each other, pushing the valve 21 upward to open the discharge pipe;

[0031] The automatic sample discharging component 2 provided by electromagnetic induction eliminates the need for the operator to manually open and close the discharging pipe, thereby reducing the risk of the operator being infected with the virus.

[0032] The remaining structural parts of Example 3 are the same as those of Example 1.

[0033] The working principle of the present invention is:

[0034] When collecting respiratory samples from incoming personnel, the virus collection liquid is first put into the temporary storage box 5 through the liquid inlet 4 for temporary storage, then the suction pump 11 is started, and the incoming personnel blow air through the disposable blowing hood 12. The blown gas sample passes through the suction pump 11, the buffer tank 10, the gas flow meter 9 and the enrichment component 8 in turn, and is finally transported to the temporary storage box 5 through the air pipe 7. The virus in the gas sample adheres to the virus collection liquid. Finally, the automatic sample discharge component 2 is turned on to make the mixed virus sample in the temporary storage box 5 enter the gas sample collection bag 1 inside the restriction box together with the virus collection liquid; after testing an incoming person, the gas sample collection bag 1 is removed and replaced, and the disposable blowing hood 12 is replaced for the next person to use; in addition, in order to increase the number of viruses collected in the respiratory sample, the enrichment component 8 usually heats the respiratory sample to a certain temperature.

[0035] The preferred embodiments of the present invention are described in detail above, but the present invention is not limited to the above embodiments. Various changes can be made within the knowledge scope of ordinary technicians in this field without departing from the purpose of the present invention.

Claims

1. A human exhaled breath sampling device based on liquid phase collection, comprising: The temporary storage box (5) is characterized by: The temporary storage box (5) is provided with liquid inlets (4) on both sides of the upper end, and the virus collection liquid is introduced into the temporary storage box (5) through the liquid inlets (4); a discharge pipe is provided at the lower end of the left side of the temporary storage box (5), and the discharge rate of the discharge pipe is controlled by an automatic sample discharge component (2); a gas sample collection bag (1) is installed on the end portion of the discharge pipe, and a restriction box is provided on the outer side of the gas sample collection bag (1); The temporary storage box (5) is provided with an air inlet port (6) at the upper end thereof, the air inlet port (6) is connected to an enrichment component (8) via an air pipe (7), the enrichment component (8) is connected to a gas flow meter (9), a buffer tank (10) and an air suction pump (11) in sequence via the air pipe (7), and a disposable blowing hood (12) is provided at the upper end of the air suction pump (11); A turbofan (3) is hingedly mounted inside the temporary storage box (5); The enrichment assembly (8) comprises an enrichment box (13), the interior of the enrichment box (13) is a cavity (17), the left and right sides of the cavity (17) are connected to the air pipe (7), the air pipe (7) on the left side is connected to the air pipe (7) on the right side via an enrichment pipe (14), the enrichment pipe (14) is made of a metal material, a resistance wire (15) is provided on the surface of the enrichment pipe (14), and a temperature probe (16) is installed inside the enrichment pipe (14); The upper end of the enrichment box (13) is connected to a heat dissipation box, a heat dissipation assembly is installed inside the heat dissipation box, a cooling fin (18) is installed inside a pipeline connecting the heat dissipation box and the enrichment box (13), the number of cooling fins (18) is two, and through holes are provided on the surfaces of the two cooling fins (18); The heat dissipation component comprises a suction fan (19) and a motor (20), wherein the suction fan (19) is mounted on an output shaft of the motor (20); The automatic sample discharging component (2) comprises a valve (21), a movable rod (22) and a sleeve (26); the valve (21) is movably mounted inside the discharging pipe; a movable rod (22) is provided at the upper end of the valve (21); the upper end of the movable rod (22) is movably mounted inside the sleeve (26); and the sleeve (26) is arranged outside the discharging pipe; A magnetic block is provided on the portion of the movable rod (22) inside the sleeve (26), and a compression spring (23) is provided on the portion of the movable rod (22) between the magnetic block and the inner wall of the sleeve (26); a conductive column (25) is provided on the inner wall of the top end of the sleeve (26), and a magnetic induction coil (24) is installed on the outer side of the conductive column (25).

Citation Information

Patent Citations

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