A winding device for concentrated growth factor sustained-release freeze-dried film

Abstract

The present invention relates to the technical field of collection and storage of freeze-dried films, and in particular to a winding device for concentrated growth factor sustained-release freeze-dried films, comprising an open box body, wherein lifting rollers and winding rollers are respectively arranged on both sides of the box body, a driving assembly for providing movement of the lifting rollers and the winding rollers is arranged on the outer side of the box body, and a pressing assembly is arranged on the top of the box body between the winding rollers and the lifting rollers; the freeze-dried film sustained-released inside the box body is attached to the surfaces of the lifting rollers and the winding rollers after freeze-drying through the action of the driving assembly, so that the freeze-dried film between the lifting rollers and the winding rollers is in a suspended state, and the winding rollers can be rotated to realize winding of the freeze-dried film, and the pressing assembly is arranged to press the front end of the winding roller so that the winding roller presses the upper surface of the freeze-dried film when winding, thereby ensuring the flatness of the winding roller when winding, and performing better winding, collection and processing of the freeze-dried film inside the box body, and the operation is simple.

Description

Technical Field

[0001] The invention relates to the technical field of collection and storage of freeze-dried films, and in particular to a winding device for concentrated growth factor sustained-release freeze-dried films. Background Art

[0002] Concentrated growth factors can promote soft tissue healing and have advantages such as higher tensile strength, more growth factors, better viscosity and higher bonding strength. They are of great significance to osteoblast growth and promotion of osteogenesis. Concentrated growth factors can be obtained by specific centrifugation methods, but the concentrated growth factors obtained by specific centrifugation methods have problems such as rapid release of concentrated growth factors, poor mechanical properties, and inability to store for a long time. To solve this problem, the concentrated growth factors can be slowly released into freeze-dried films for storage.

[0003] At present, the method for sustained-release of concentrated growth factors into freeze-dried films is as follows: disperse the concentrated growth factors in an aqueous solution of sodium alginate to obtain a mixed solution; add the mixed solution dropwise to an aqueous solution containing divalent metal cations while stirring so that the sodium alginate coats the concentrated growth factors to obtain composite microspheres of concentrated growth factors and sodium alginate; disperse the composite microspheres in an aqueous solution of chitosan, freeze-dry, and obtain a sustained-release freeze-dried film of concentrated growth factors; since the freeze-dried film will adhere to the inside of the processing device when it is frozen in a freeze dryer, there is a certain inconvenience in collecting and storing the freeze-dried film. Therefore, a winding device for a sustained-release freeze-dried film of concentrated growth factors is needed to solve the above problems. Summary of the Invention

[0004] (1) Technical problems solved

[0005] The purpose of the present invention is to overcome the deficiencies of the prior art and to provide a winding device for a concentrated growth factor sustained-release freeze-dried film.

[0006] (2) Technical solution

[0007] A winding device for concentrated growth factor sustained-release freeze-dried film comprises an open box body, with a lifting roller and a winding roller respectively provided on both sides of the box body, a driving component for providing movement of the lifting roller and the winding roller provided on the outer side of the box body, and a pressing component provided on the top of the box body between the winding roller and the lifting roller.

[0008] Preferably, the driving assembly includes a lifting rack and a winding rack that are rotatably connected to the lifting roller and the winding roller respectively. A rotating gear is engaged on one side of the lifting rack and the winding rack. The outer sides of the two rotating gears are fixedly connected to pulleys. The two pulleys are connected by a transmission belt, and a turntable is fixedly connected to the outer side of one of the pulleys.

[0009] Preferably, the pressing assembly includes two L-shaped plates respectively fixedly connected to the top of the box body, the bottom of the L-shaped plate is rotatably connected to a V-shaped rod, one end of the V-shaped rod is fixedly connected to a pressing roller extending to the inside of the box body, the V-shaped rod is located between the top of the pressing roller and the L-shaped plate and is fixedly connected to a pressing spring, and the top of the L-shaped plate is threadedly connected to a bolt that contacts one end of the V-shaped rod.

[0010] Preferably, when the winding roller extends to the outside of the box body, the bottom end of the pressing roller is located below the line connecting the lifting roller and the winding roller.

[0011] Preferably, the two ends of the winding roller are detachably connected to the two winding racks, and the two ends of the lifting roller are rotatably connected to the two lifting racks.

[0012] Preferably, a push rod is inserted into the top of the winding rack, and a groove adapted to the push rod is formed at one end of the V-shaped rod away from the pressing roller.

[0013] Preferably, when the push rod is in contact with the groove, the distance between the pressing roller and the bottom of the box body is smaller than the distance between the winding roller and the bottom of the box body.

[0014] (3) Beneficial effects

[0015] The present invention provides a winding device for a concentrated growth factor sustained-release freeze-dried film, which has the following advantages:

[0016] 1. The freeze-dried film slowly released inside the box is attached to the surface of the lifting roller and the winding roller after freeze-drying through the action of the driving component, so that the freeze-dried film between the lifting roller and the winding roller is in a suspended state. The winding roller is rotated to realize the winding of the freeze-dried film. The pressing component is set to press the front end of the winding roller so that the winding roller presses the upper surface of the freeze-dried film when winding, ensuring the flatness of the winding roller when winding. After the freeze-dried film is freeze-dried, the freeze-dried film inside the box is better wound and collected, and the operation is simple;

[0017] 2. After the height of the winding rack is adjusted, the top rod can contact the groove of the V-shaped rod, causing the V-shaped rod to rotate, thereby causing the pressing roller at the other end of the V-shaped rod to move downward. The height of the pressing roller can be adjusted without rotating the bolt. At this time, the setting of the bolt can further limit the position of the pressing roller to ensure the stability of the pressing roller. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only for protecting some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0019] Figure 1 This is a schematic diagram of the main cross-sectional structure of embodiment 1 of the present invention;

[0020] Figure 2 This is a schematic diagram of the main structure of the first embodiment of the present invention;

[0021] Figure 3 Schematic diagram of the top view of the structure of the first embodiment of the present invention;

[0022] Figure 4 This is a schematic diagram of the main cross-sectional structure of Example 2 of the present invention.

[0023] In the accompanying drawings, the components represented by the reference numerals are as follows:

[0024] 1. Box body; 2. Lifting roller; 3. Winding roller; 4. Driving assembly; 41. Lifting rack; 42. Winding rack; 43. Rotating gear; 44. Pulley; 45. Transmission belt; 46. Turntable; 5. Pressing assembly; 51. L-shaped plate; 52. V-shaped rod; 53. Pressing roller; 54. Pressing spring; 55. Bolt; 6. Push rod; 7. Groove. DETAILED DESCRIPTION

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts shall fall within the scope of protection of the present invention.

[0026] The present invention provides an embodiment 1:

[0027] See also Figure 1-3The lifting roller 2 and the winding roller 3 are respectively provided with the lifting roller 2 and the winding roller 3. The outer side of the box body 1 is provided with a driving assembly 4 for providing the lifting roller 2 and the winding roller 3 with movement. The top of the box body 1 is provided with a pressing assembly 5 between the winding roller 3 and the lifting roller 2. Specifically, the winding roller 3 and the lifting roller 2 are provided to release the freeze-dried film slowly from the inside of the box body 1 through the action of the driving assembly 4, so that the freeze-dried film adheres to the surface of the lifting roller 2 and the winding roller 3 after freeze-drying, so that the freeze-dried film between the lifting roller 2 and the winding roller 3 is in a suspended state. The winding roller 3 is rotated to realize the winding of the freeze-dried film. The pressing assembly 5 is provided to press the front end of the winding roller 3 so that the winding roller 3 presses the upper surface of the freeze-dried film when winding, thereby ensuring the flatness of the winding roller 3 when winding.

[0028] The drive assembly 4 includes a lifting rack 41 and a winding rack 42 that are rotatably connected to the lifting roller 2 and the winding roller 3 respectively. One side of the lifting rack 41 and the winding rack 42 is meshed with a rotating gear 43. The outer sides of the two rotating gears 43 are fixedly connected to pulleys 44. The two pulleys 44 are connected by a transmission belt 45. The outer side of one of the pulleys 44 is fixedly connected to a turntable 46. Specifically, a limiting device is provided on the outer side of the turntable 46 for limiting the rotation of the turntable 46 after adjustment. Through the rotation of the turntable 46 outside the box body 1, the belt pulley 44 and the transmission belt 45 drive the two rotating gears 43 to rotate synchronously, so that the lifting rack 41 and the winding rack 42 are synchronously raised, so that the lifting roller 2 and the winding roller 3 move toward the top of the box body 1 until the winding roller 3 moves to the top of the box body 1, so as to increase the hanging length of the freeze-dried film between the lifting roller 2 and the winding roller 3, and realize the winding process of the freeze-dried film by rotating the winding roller 3.

[0029] The pressing assembly 5 includes two L-shaped plates 51 respectively fixedly connected to the top of the box body 1. The bottom of the L-shaped plate 51 is rotatably connected to a V-shaped rod 52. One end of the V-shaped rod 52 is fixedly connected to a pressing roller 53 extending into the interior of the box body 1. The V-shaped rod 52 is located between the top of the pressing roller 53 and the L-shaped plate 51 and is fixedly connected to a pressing spring 54. The top of the L-shaped plate 51 is threadedly connected to a bolt 55 that contacts one end of the V-shaped rod 52. Specifically, before the turntable 46 is rotated, By rotating the internal thread of the L-shaped plate 51 through the bolt 55, the V-shaped rod 52 is driven to rotate through the bottom end of the bolt 55, so that the pressing spring 54 is stretched, so that the pressing roller 53 at the bottom of the V-shaped rod 52 is located inside the box body 1. At this time, the lifting roller 2, the winding roller 3 and the pressing roller 53 are at three heights: lower, middle and upper inside the box body 1. At this time, the winding process of the freeze-dried film can be achieved by rotating the winding roller 3, which makes the winding and collection of the freeze-dried film convenient and the flatness during winding is good.

[0030] When the winding roller 3 extends to the outside of the box body 1, the bottom end of the pressing roller 53 is located below the line connecting the lifting roller 2 and the winding roller 3. Specifically, when the driving component 4 adjusts the height of the lifting roller 2 and the winding roller 3, the pressing roller 53 flattens and presses the upper surface of the freeze-dried film, thereby ensuring the flatness of the freeze-dried film when the winding roller 3 winds it.

[0031] The two ends of the winding roller 3 are detachably connected to the two winding racks 42, and the two ends of the lifting roller 2 are rotatably connected to the two lifting racks 41. Specifically, the winding roller 3 is detachably connected, which ensures that the freeze-dried film and the winding roller 3 are stored together after the winding process.

[0032] A specific application of the first embodiment is as follows: after freeze drying, the freeze-dried film in the box body 1 is attached to the surface of the lifting roller 2 and the winding roller 3, so that the freeze-dried film between the lifting roller 2 and the winding roller 3 is in a suspended state. At this time, the bolt 55 is rotated on the inner thread of the L-shaped plate 51, and the bottom end of the bolt 55 drives the V-shaped rod 52 to rotate, so that the pressing spring 54 is stretched, so that the pressing roller 53 at the bottom of the V-shaped rod 52 is located inside the box body 1. At this time, the lifting roller 2, the winding roller 3 and the pressing roller 53 are at three heights: lower, middle and upper inside the box body 1, and are connected by the turntable 46 outside the box body 1. The rotation of the pulley 44 and the transmission belt 45 causes the two rotating gears 43 to rotate synchronously, causing the lifting rack 41 and the winding rack 42 to rise synchronously, so that the lifting roller 2 and the winding roller 3 move toward the top of the box body 1 until the winding roller 3 moves to the top of the box body 1, which is used to increase the hanging length of the freeze-dried film between the lifting roller 2 and the winding roller 3. By rotating the winding roller 3, the freeze-dried film is wound, ensuring that the freeze-dried film inside the box body 1 is better wound and collected after freeze-drying, and the operation is simple.

[0033] Based on the first embodiment, the present invention provides a second embodiment:

[0034] See also Figure 4 , a push rod 6 is inserted into the top of the winding rack 42, and a groove 7 adapted to the push rod 6 is opened at the end of the V-shaped rod 52 away from the pressing roller 53. Specifically, after the height of the winding rack 42 is adjusted, the push rod 6 can contact the groove 7 of the V-shaped rod 52, so that the V-shaped rod 52 rotates, thereby causing the pressing roller 53 at the other end of the V-shaped rod 52 to move downward, and the height of the pressing roller 53 can be adjusted without rotating and adjusting the bolt 55. At this time, the setting of the bolt 55 can further limit the position of the pressing roller 53 to ensure the stability of the pressing roller 53. The push rod 6 is connected to the winding rack 42, and push rods 6 of different lengths can be used to adjust the distance between the pressing roller 53 and the inside of the box body 1.

[0035] When the push rod 6 contacts the groove 7, the distance between the pressing roller 53 and the bottom of the box body 1 is smaller than the distance between the winding roller 3 and the bottom of the box body 1. Specifically, the setting of the groove 7 is used to limit the top end of the push rod 6 to a certain extent when the push rod 6 contacts the V-shaped rod 52, so that the push rod 6 has better stability when squeezing and rotating the V-shaped rod 52.

[0036] Based on the operating process of Example 1, it can be known that after the height of the winding rack 42 is adjusted, the top rod 6 can contact the groove 7 of the V-shaped rod 52, causing the V-shaped rod 52 to rotate, thereby causing the pressing roller 53 at the other end of the V-shaped rod 52 to move downward. The height adjustment of the pressing roller 53 can be achieved without rotating the bolt 55. At this time, the setting of the bolt 55 can further limit the position of the pressing roller 53 to ensure the stability of the pressing roller 53.

[0037] Throughout this specification, references to terms such as "one embodiment," "example," and "specific example" indicate that the specific features, structures, materials, or characteristics described in conjunction with that embodiment or example are included in at least one embodiment or example of the present invention. In this specification, schematic representations of these terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

[0038] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the present invention to specific embodiments. Obviously, many modifications and variations are possible based on the contents of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A winding device for concentrated growth factor sustained-release freeze-dried film, comprising an open box (1), characterized in that: A lifting roller (2) and a winding roller (3) are respectively arranged on both sides of the box body (1); a driving component (4) for providing movement of the lifting roller (2) and the winding roller (3) is arranged on the outer side of the box body (1); a pressing component (5) is arranged on the top of the box body (1) between the winding roller (3) and the lifting roller (2); the driving component (4) comprises a lifting rack (41) and a winding rack (42) which are respectively connected to the lifting roller (2) and the winding roller (3); a rotating gear (43) is meshed on one side of the lifting rack (41) and the winding rack (42); a pulley (44) is fixedly connected to the outer side of the two rotating gears (43); the two pulleys (44) are connected to each other by a transmission belt (45); one of the pulleys (44) is connected to the lifting roller (2) and the winding roller (3); The outer side of the box body (1) is fixedly connected with a turntable (46); the pressing assembly (5) comprises two L-shaped plates (51) respectively fixedly connected to the top of the box body (1); the bottom of the L-shaped plate (51) is rotatably connected with a V-shaped rod (52); one end of the V-shaped rod (52) is fixedly connected with a pressing roller (53) extending into the interior of the box body (1); the V-shaped rod (52) is located between the top of the pressing roller (53) and the L-shaped plate (51) and is fixedly connected with a pressing spring (54); the top of the L-shaped plate (51) is threadedly connected with a bolt (55) in contact with one end of the V-shaped rod (52); the top of the winding rack (42) is plugged with a push rod (6); the end of the V-shaped rod (52) away from the pressing roller (53) is provided with a groove (7) adapted to the push rod (6).

2. The winding device of the concentrated growth factor sustained-release freeze-dried film according to claim 1, characterized in that: When the winding roller (3) extends to the outside of the box body (1), the bottom end of the pressing roller (53) is located below the line connecting the lifting roller (2) and the winding roller (3).

3. The winding device of the concentrated growth factor sustained-release freeze-dried film according to claim 1, characterized in that: The two ends of the winding roller (3) are respectively detachably connected to the two winding racks (42), and the two ends of the lifting roller (2) are rotatably connected to the two lifting racks (41).

4. The winding device of the concentrated growth factor sustained-release freeze-dried film according to claim 1, characterized in that: When the push rod (6) contacts the groove (7), the distance between the pressing roller (53) and the bottom of the box body (1) is smaller than the distance between the winding roller (3) and the bottom of the box body (1).

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