Surface treatment process of implant

Abstract

The present invention discloses a surface treatment process for an implant. The process comprises the following steps: the implant is sandblasted, then acid treated, irradiated with ultraviolet light of wavelength 320-400nm for 20-40s, and then placed in a packaging bottle, wherein the packaging bottle contains a protective liquid. The implant of the present invention is first sandblasted, then acid treated, then activated by ultraviolet light, and finally placed in a packaging bottle. Under the protection of the protective liquid in the packaging bottle until use, the hydrophilicity of the implant is protected from changing, thereby meeting the use requirements.

Description

Technical Field

[0001] The invention relates to a surface treatment process of an implant, and belongs to the technical field of medical devices. Background Art

[0002] Dental implants are implanted into the upper and lower jaws of the human body through surgical procedures. After the surgical wound heals, a repair base and crown are installed on the upper part. In modern dentistry, dental implants are widely used in tooth loss and repair due to their beauty, comfort and long life. They are called the third set of teeth for humans.

[0003] Hydrophilic dental implants tend to have better biological activity. A series of studies have shown that hydrophilic implants promote the differentiation of bone cells and are particularly effective for early bone integration. However, existing implants generally have a high contact angle (above 30°), and the hydrophilicity of some hydrophilic implants decreases significantly after being placed for a period of time.

[0004] Ultraviolet irradiation is a process that can activate the surface of the implant before dental implant surgery to regain its hydrophilic surface. Although the corresponding implant activation instrument can make the implant hydrophilic to a certain extent, it has not been widely promoted in the market. The main reason is that ordinary UVC ultraviolet rays (wavelength 253.7nm) have low activation power, unconcentrated energy, and long activation time (generally more than 4 hours). During clinical use, doctors need to prepare for implant activation 4 hours in advance, which is cumbersome and time-consuming in actual operation. In addition, the implant cannot be sterilized again after removal. Once the operation time needs to be changed due to patient or doctor reasons, the implant will no longer be able to be used, resulting in waste. Summary of the invention

[0005] In order to overcome the deficiencies of the prior art, the present invention provides a surface treatment process for an implant.

[0006] The present invention is achieved through the following technical solutions:

[0007] A surface treatment process for an implant comprises the following steps: the implant is sandblasted and then acid treated, irradiated with ultraviolet light of a wavelength of 320-400nm for 20-40s, and then placed in a packaging bottle containing a protective liquid.

[0008] The surface treatment process of the implant described above, the sandblasting treatment specifically includes: using two sand particles with different particle sizes to sandblast the implant, dividing the implant into an upper part and a lower part, and the particle size of the sandblasted on the upper part is smaller than the particle size of the sandblasted on the lower part.

[0009] In the surface treatment process of the implant, the roughness of the upper part is 0.5-1 μm, and the roughness of the lower part is 1.5-2.5 μm.

[0010] In the surface treatment process of the implant, the length of the upper part is 0.5-3 mm.

[0011] The specific steps of the surface treatment process of the implant include: treating with a mixture of hydrochloric acid and sulfuric acid for 2-8 minutes.

[0012] In the surface treatment process of the implant, the weight proportions of the hydrochloric acid and the sulfuric acid are 10-20 parts and 80-100 parts respectively; the mass fraction of the hydrochloric acid is 10-35%, and the mass fraction of the sulfuric acid is 40-65%.

[0013] The surface treatment process of an implant is described, the packaging bottle includes a main body, a partition is arranged on the main body, the partition divides the main body into a first part and a second part, the implant is placed in the second part, and the protective liquid is arranged in the first part; the partition is detachable to allow the first part and the second part to be connected.

[0014] In the surface treatment process of the implant, the protective liquid is a mixture of saline, BMP and RGD or a mixture of BMP and EPO.

[0015] In the surface treatment process of an implant, the implant is vertically located in the second part.

[0016] The beneficial effects achieved by the present invention are:

[0017] The implant of the present invention is first sandblasted, then acid treated and then activated by ultraviolet light, and finally placed in a packaging bottle. Under the protection of the protective liquid in the packaging bottle until use, the hydrophilicity of the implant is protected from change, thus meeting the use requirements.

[0018] The higher roughness of the lower part of the implant can accelerate bone integration, while the lower roughness of the upper part can effectively prevent bacterial invasion, thereby improving the implantation success rate of the implant of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the packaging bottle.

[0020] In the figure: 1. main body, 11. first part, 12. second part, 2. partition, 3. implant. DETAILED DESCRIPTION

[0021] The present invention is further described below. The following examples are only used to more clearly illustrate the technical solution of the present invention, and are not intended to limit the protection scope of the present invention.

[0022] Example 1

[0023] A surface treatment process for an implant comprises the following steps:

[0024] (1) Sandblasting: Sandblast the implant with two different particle sizes to divide the implant into an upper part and a lower part. The particle size of the sandblasted on the upper part is smaller than that of the sandblasted on the lower part. The roughness of the upper part is 0.5 μm, and the roughness of the lower part is 1.5 μm; the length of the upper part is 0.5-3 mm;

[0025] (2) Acid treatment: using a mixture of hydrochloric acid and sulfuric acid for 2 minutes; the weight proportions of the hydrochloric acid and sulfuric acid are 10 parts and 80 parts respectively; the mass fraction of the hydrochloric acid is 10%, and the mass fraction of the sulfuric acid is 40%;

[0026] (3) Ultraviolet light treatment: After the implant surface is cleaned multiple times with purified water, it is irradiated with ultraviolet light at a wavelength of 320 nm for 20 seconds;

[0027] (4) Packaging: Then place in packaging bottle.

[0028] The contact angle of this example was measured to be 3° before packaging, and the contact angle was 6° after being taken out of the packaging bottle one month later.

[0029] The packaging bottle comprises a main body 1, on which a partition 2 is arranged, the partition 2 divides the main body 1 into a first part 11 and a second part 12, the second part 12 contains an implant 3, and the first part 11 contains a protective liquid; the partition 2 is detachable, so that the first part 11 and the second part 12 are connected. The protective liquid is saline. The implant 3 is vertically arranged in the second part 12.

[0030] When it is to be used, the partition 2 is disassembled, and the protective liquid falls into the second part 12 to cover the implant 3. With the packaging bottle of this embodiment, the contact angle after being treated with the protective liquid is 4°.

[0031] The higher roughness of the lower part of the implant can accelerate bone integration, while the lower roughness of the upper part can effectively prevent bacterial invasion, thereby improving the implantation success rate of the implant of the present application.

[0032] Example 2

[0033] A surface treatment process for an implant comprises the following steps:

[0034] (1) Sandblasting: Sandblast the implant with two different particle sizes to divide the implant into an upper part and a lower part. The particle size of the sandblasted on the upper part is smaller than that of the sandblasted on the lower part. The roughness of the upper part is 1 μm, and the roughness of the lower part is 2.5 μm; the length of the upper part is 0.5-3 mm;

[0035] (2) Acid treatment: using a mixture of hydrochloric acid and sulfuric acid for 8 minutes; the weight proportions of the hydrochloric acid and sulfuric acid are 20 parts and 100 parts respectively; the mass fraction of the hydrochloric acid is 35%, and the mass fraction of the sulfuric acid is 65%;

[0036] (3) Ultraviolet light treatment: After the implant surface is cleaned multiple times with purified water, it is irradiated with ultraviolet light with a wavelength of 400 nm for 40 seconds;

[0037] (4) Packaging: Then place in packaging bottle.

[0038] The contact angle of this example was measured to be 4° before packaging, and the contact angle was 9° after the sample was taken out of the packaging bottle two months later.

[0039] The packaging bottle comprises a main body 1, on which a partition 2 is arranged, the partition 2 divides the main body 1 into a first part 11 and a second part 12, the second part 12 contains an implant 3, and the first part 11 contains a protective liquid; the partition 2 is detachable, so that the first part 11 and the second part 12 are connected. The protective liquid is a mixture of BMP and RGD. The implant 3 is vertically arranged in the second part 12.

[0040] When it is to be used, the partition 2 is disassembled, and the protective liquid falls into the second part 12 to cover the implant 3. With the packaging bottle of this embodiment, the contact angle after being treated with the protective liquid is 4°.

[0041] Example 3

[0042] A surface treatment process for an implant comprises the following steps:

[0043] (1) Sandblasting: Sandblast the implant with two different particle sizes to divide the implant into an upper part and a lower part. The particle size of the sandblasted on the upper part is smaller than that of the sandblasted on the lower part. The roughness of the upper part is 1 μm, and the roughness of the lower part is 2 μm; the length of the upper part is 0.5-3 mm;

[0044] (2) Acid treatment: using a mixture of hydrochloric acid and sulfuric acid for 5 minutes; the weight proportions of the hydrochloric acid and sulfuric acid are 15 parts and 90 parts respectively; the mass fraction of the hydrochloric acid is 20%, and the mass fraction of the sulfuric acid is 50%;

[0045] (3) Ultraviolet light treatment: After the implant surface is cleaned multiple times with purified water, it is irradiated with ultraviolet light at a wavelength of 380 nm for 30 seconds;

[0046] (4) Packaging: Then place in packaging bottle.

[0047] The contact angle of this example was measured to be 4° before packaging, and the contact angle was 12° after the sample was taken out of the packaging bottle three months later.

[0048] The packaging bottle comprises a main body 1, on which a partition 2 is arranged, the partition 2 divides the main body 1 into a first part 11 and a second part 12, the second part 12 contains an implant 3, and the first part 11 contains a protective liquid; the partition 2 is detachable, so that the first part 11 and the second part 12 are connected. The protective liquid is a mixture of BMP and EPO. The implant 3 is vertically arranged in the second part 12.

[0049] When it is to be used, the partition 2 is disassembled, and the protective liquid falls into the second part 12 to cover the implant 3. With the packaging bottle of this embodiment, the contact angle after being treated with the protective liquid is 5°.

[0050] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A surface treatment process for an implant, characterized in that: The method comprises the following steps: the implant is subjected to sandblasting treatment, then acid treatment, irradiated with ultraviolet light of a wavelength of 380 nm for 30 seconds, and then placed in a packaging bottle containing a protective liquid; The sandblasting treatment specifically includes: using two sand particles with different particle sizes to sandblast the implant, dividing the implant into an upper part and a lower part, wherein the particle size of the sand particles blasted on the upper part is smaller than the particle size of the sand particles blasted on the lower part; The roughness of the upper part is 1 μm, and the roughness of the lower part is 2 μm; The specific steps of the acid treatment are: treating with a mixture of hydrochloric acid and sulfuric acid for 5 minutes; The weight proportions of the hydrochloric acid and sulfuric acid are 15 and 90 parts respectively; the mass fraction of the hydrochloric acid is 20%, and the mass fraction of the sulfuric acid is 50%; The packaging bottle comprises a main body, on which a partition is arranged, the partition divides the main body into a first part and a second part, the implant is placed in the second part, and the first part is provided with a protective liquid; the partition is detachable, so that the first part and the second part are connected; The protective solution is a mixture of saline, BMP and RGD or a mixture of BMP and EPO.

2. The surface treatment process of an implant according to claim 1, characterized in that: The length of the upper portion is 0.5-3 mm.

3. The surface treatment process of an implant according to claim 1, characterized in that: The implant is vertically disposed in the second portion.

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