A method of delivering a fluid to the nasal airway of a user

Abstract

The present invention discloses a method for delivering fluid to the nasal airway of a user, including steps S1 to S5, S1, providing a fluid delivery device; S2, applying a loading force to the supply unit of the fluid delivery device and locking it in a first position; S3, respectively configuring the nasal piece and the oral piece of the fluid delivery device to the nose and mouth of the user; S4, the user outputs the first fluid through the oral piece, and the supply unit is unlocked from the first position by the pressure of the first fluid; S5, the supply unit moves to the second position, and delivers the second fluid to the nasal airway through the nasal piece, and at the same time, the first fluid flows to the nasal piece and gives constant power assistance to the second fluid. The method for delivering fluid to the nasal airway of the user is simple to operate, compatible with all people, and the blowing force is stable and controllable, and the depth of the drug delivered to the nose each time is nearly consistent, which is more conducive to achieving precise treatment. Before the air is blown to unlock, there is no possibility of triggering the spray of the supply unit, realizing the function of preventing misoperation.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and more particularly to a method for delivering fluid to the nasal airway of a user. Background Art

[0002] As the environment deteriorates, the number of nasal diseases in the human body is on the rise. Nasal drug delivery devices are widely used in nasal treatment because they can deliver drugs directly to the nose. Medically proven, daily nasal cleaning can effectively relieve various rhinitis symptoms such as nasal congestion and runny nose, and can reduce the invasion of bacteria and allergens into the nasal cavity, thereby improving one's own respiratory immunity.

[0003] For existing dual-powered nasal sprays, when they are used, air is blown first to provide auxiliary power, and then a switch is pressed to activate the release of the drug, or the blowing and pressing are operated synchronously in the hope of delivering the drug deeply into the user's nasal airway.

[0004] In actual use, it is found that among the above operation methods, the first operation method requires continuous blowing, which has high requirements on lung capacity, and the second operation method has high requirements on human body reaction and coordination of movements. The above two methods have certain limitations and are not compatible with all people. In addition, it is difficult to control the size of the blowing force during operation. Because the blowing force of the mouth-blown gas output by different users is different, the depth of drug delivery to the nose also changes accordingly. Especially for children or the elderly, the output blowing force is small, and the enhanced power may not be able to reach the predetermined drug delivery position, thus affecting the treatment effect.

[0005] Based on the above problems, the present application proposes a method for delivering fluid to the nasal airway of a user. Summary of the invention

[0006] An object of the present invention is to provide a method for delivering fluid to the nasal airway of a user, at least for optimizing the drug administration operation and improving the effect of drug delivery.

[0007] The purpose of the present invention is achieved by the following technical solutions:

[0008] A method of delivering a fluid to the nasal airway of a user, comprising the steps of:

[0009] S1. providing a fluid delivery device;

[0010] S2, applying a loading force to the supply unit of the fluid delivery device and locking it in the first position;

[0011] S3, placing the nosepiece and mouthpiece of the fluid delivery device on the nose and mouth of the user respectively;

[0012] S4, the user outputs the first fluid through the mouthpiece, and the supply unit is unlocked from the first position by the pressure of the first fluid;

[0013] S5. The supply unit moves to the second position and delivers the second fluid to the nasal airway through the nasal holder. At the same time, the first fluid flows toward the nasal holder and provides constant power assistance to the second fluid.

[0014] In some embodiments, the nose piece extends at least 2 cm into the user's nose.

[0015] In some embodiments, the end of the nose piece closer to the user's nose is tapered.

[0016] In some embodiments, during step S4 to step S5, the user's soft palate is in a closed state.

[0017] In some embodiments, the fluid delivery device further comprises a valve unit, wherein the valve unit is disposed in a flow passage connecting the nasal piece and the oral piece;

[0018] In the initial state, the valve unit cuts off the flow channel and locks the supply unit in the first position;

[0019] When the pressure of the first fluid reaches a preset pressure, the valve unit opens the flow channel and unlocks the supply unit from the first position.

[0020] In some embodiments, the flow channel includes an air storage chamber, and the air storage chamber is provided with an inlet and an outlet;

[0021] The valve unit is rotatably arranged between the inlet and the outlet, and the valve unit has two deflection strokes:

[0022] In the first deflection stroke, the outlet is closed, and the first fluid enters the air storage chamber from the inlet and continues to accumulate; in the second deflection stroke, the outlet is opened, and the first fluid quickly flows from the air storage chamber to the nasal bearing.

[0023] In some embodiments, the fluid delivery device further comprises a loading mechanism;

[0024] In the initial state, the loading mechanism is engaged with the valve unit so that the supply unit is locked in the first position;

[0025] When the pressure of the first fluid reaches a preset pressure, the loading mechanism and the valve unit are separated from each other, so that the supply unit moves to the second position.

[0026] In some embodiments, the fluid delivery device further comprises an actuation unit;

[0027] The actuating unit is connected to the loading mechanism, and by operating the actuating unit, the loading mechanism can be driven to apply a loading force to the supply unit in advance.

[0028] In some embodiments, when the user outputs the first fluid through the mouthpiece, the actuating unit is always in a squeezed state.

[0029] In some embodiments, the first fluid is oral gas from the user's mouth;

[0030] The second fluid is a powdery substance, a granular substance or a liquid substance, and the second fluid is delivered in the form of a spray or a jet.

[0031] In some embodiments, the fluid delivery device is configured to provide an actuation performance of 0.8 L / min when a user outputs a first fluid pressure of at least 3 kPa.

[0032] In some embodiments, at a pressure of 3 kPa, at least 85% of the first fluid in the mouthpiece flows to the nasal piece.

[0033] In some embodiments, the supply unit provides delivery of the second fluid in less than 120 ms from unlocking.

[0034] In some embodiments, the fluid delivery device has a spray angle in the sagittal plane of not less than 35°; and / or,

[0035] The fluid delivery device has a spray angle of no greater than 30° in the vertical sagittal plane.

[0036] Compared with the prior art, the beneficial effects of the present invention include at least:

[0037] 1. This method is easy to operate, compatible with all people, and the blowing force is stable and controllable. The depth of drug delivery to the nose is almost consistent each time, which is more conducive to precise treatment.

[0038] 2. Before the air is blown to unlock, no matter whether the actuating unit is operated or not, the supply unit cannot trigger the spray, thus realizing the function of preventing misoperation. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 It is a schematic diagram of the three-dimensional structure of a dual-power-driven fluid delivery device.

[0040] Figure 2 It is a schematic diagram of the exploded structure of a dual-power-driven fluid delivery device.

[0041] Figure 3 It is a schematic structural diagram of a dual-power-driven fluid delivery device in a first position with a valve unit locked.

[0042] Figure 4 It is a schematic structural diagram of a dual-power-driven fluid delivery device in a first position and a valve unit at a sealing critical point.

[0043] Figure 5 It is a schematic diagram of the structure of the dual-power-driven fluid delivery device when it is in the second position and the valve unit is unlocked.

[0044] Figure 6 It is a schematic structural diagram of a single-power-driven fluid delivery device in a first position with a valve unit locked.

[0045] Figure 7 It is a schematic structural diagram of a single-power-driven fluid delivery device in a second position with the valve unit unlocked.

[0046] Figure 8 It is a schematic diagram of the connection structure between the actuating unit and the loading structure.

[0047] Fig. 9 It is a schematic diagram of the coordination between the valve unit, the loading mechanism and the air storage chamber.

[0048] Fig.10 It is a structural diagram of the supply unit.

[0049] In the figure:

[0050] 1. Shell; 11. First half shell; 12. Second half shell; 13. Mounting cavity; 14. Sealing groove; 15. Guide groove;

[0051] 2. Nose bearing; 21. Ring channel;

[0052] 3. Supply unit; 31. Nozzle; 32. Pump assembly; 321. Through hole; 33. Fluid receiving member;

[0053] 4. loading mechanism; 41. first cylinder; 411. locking tongue; 4111. first locking surface; 4112. first guide surface; 412. stopper; 42. second cylinder; 421. limiting groove; 422. slider; 423. driven block; 43. elastic member;

[0054] 5. Actuating unit; 51. Pressing portion; 52. Connecting portion; 521. Guide groove; 5211. Driving section; 5212. Anti-slip section;

[0055] 6. valve unit; 61. first rotating part; 62. second rotating part; 63. third rotating part; 64. latching protrusion; 641. second locking surface; 642. second guide surface;

[0056] 7. Oral inheritance;

[0057] 8. air storage chamber; 81. inlet; 82. outlet; 83. first arc surface; 84. second arc surface; 85. third arc surface; 86. air hole;

[0058] 9. Seals. DETAILED DESCRIPTION

[0059] Example embodiments will now be described more fully with reference to the accompanying drawings. However, example embodiments can be implemented in a variety of forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided to make the present invention more comprehensive and complete and to fully convey the concepts of example embodiments to those skilled in the art. The same reference numerals in the figures represent the same or similar structures, and thus their repeated description will be omitted.

[0060] The words expressing positions and directions described in the present invention are all explained with reference to the accompanying drawings as examples, but they can be changed as needed, and all such changes are included in the protection scope of the present invention.

[0061] See also Figures 1 to 9 As shown, the present invention discloses a fluid delivery device, which is mainly used in the treatment of nasal diseases. By delivering drugs deep into the respiratory tract, the absorption efficiency of the drugs is improved, and the degradation of the drugs in the digestive system is reduced, thereby exerting the therapeutic effect more quickly.

[0062] The fluid delivery device of the present application may be a single-power nasal spray, that is, it is operated by only one power source, such as a manual switch, to spray the drug. Figure 6 and Figure 7 As shown, the fluid delivery device mainly includes a housing 1 , a nasal piece 2 , a supply unit 3 , a loading mechanism 4 and an actuating unit 5 .

[0063] The housing 1 is constructed as a single-handed grip, which contains a supply unit 3, a loading mechanism 4 and a part of an actuating unit 5. In this embodiment, the housing 1 is generally an elongated box body, and a mounting cavity 13 is provided inside the housing 1, in which both the supply unit 3 and the loading mechanism 4 can be disposed.

[0064] The nose piece 2 is arranged on the housing 1, so that the nose piece 2 is sealed and connected to the housing 1. When in use, the nose piece 2 is arranged on the nose of the user, and the second fluid can be delivered to the nasal airway of the user in cooperation with the supply unit 3.

[0065] The supply unit 3 is used to store a second fluid. The second fluid may be a powdery substance, a granular substance or a liquid substance. The second fluid has a specific therapeutic effect.

[0066] The supply unit 3 can deliver the second fluid outward under the drive of an external force (such as a loading force), for example, in the form of a spray or a jet. In this embodiment, the supply unit 3 can move between a first position and a second position, wherein the first position is defined as an invalid working position. Figure 6 As shown, in this position, the supply unit 3 cannot be triggered to output the second fluid; the second position is defined as the effective working position, such as Figure 7 As shown, in this position, the supply unit 3 can be triggered to output the second fluid.

[0067] The loading mechanism 4 is connected to the supply unit 3 and is used to apply a loading force to the supply unit 3. In this embodiment, the loading mechanism 4 can be manually operated in advance, for example, by squeezing the actuating unit 5 to apply a loading force to the supply unit 3, so that the supply unit 3 can be driven to move from the first position to the second position after the valve unit 6 is unlocked.

[0068] The actuating unit 5 is linked with the loading mechanism 4, and the user can drive the loading mechanism 4 to provide the loading force by operating the actuating unit 5. In this embodiment, the actuating unit 5 is rotatably arranged on one side of the housing 1 and connected to the loading mechanism 4. This design facilitates the user to apply the actuating force by gripping and pressing, which improves the convenience of operation compared to the conventional up and down pressing to apply the actuating force.

[0069] Still see Figure 6 As shown, in the fluid delivery device (single-power nasal sprayer), in the initial state, the supply unit 3 is locked in the first position. In some embodiments, the supply unit 3 can be directly restricted in the first position by a locking member (such as a pin, a hook, etc., not shown), or can be indirectly restricted in the first position by cooperating with the loading mechanism 4 through the locking member.

[0070] Exemplarily, the locking member in this embodiment is a valve unit 6, which is arranged on one side of the supply unit 3 and can be engaged with the loading mechanism 4 to indirectly lock the supply unit 3 in the first position. Without being unlocked, the supply unit 3 always remains in the first position, that is, the invalid working position. Therefore, no matter whether the actuating unit 5 is operated or not, the supply unit 3 does not have the possibility of triggering the spray, thereby realizing the function of preventing misoperation and improving the reliability of the device.

[0071] like Figure 7 As shown, when in use, the user operates the actuating unit 5 to drive the loading mechanism 4 to apply a loading force to the supply unit 3. After the lock is released (the toggle valve unit 6 is separated from the loading mechanism 4), the supply unit 3 moves to the second position and delivers the second fluid through the nasal piece 2.

[0072] It is worth noting that in this device, since the supply unit 3 is always subjected to a loading force by the loading mechanism 4, at the moment when the valve unit 6 is unlocked, the supply unit 3 will quickly move to the second position in a catapult-like motion. Compared with the conventional method of driving the supply unit 3, the trigger force acting on the supply unit 3 is greater and the speed is faster. Accordingly, the supply unit 3 will also move quickly and deliver the second fluid to a farther position by squeezing the pump assembly 32, thereby effectively improving the delivery stroke.

[0073] In addition, the fluid delivery device of the present application can also be a dual-power nasal spray, that is, while the single-power operation allows the drug to be sprayed, the additional first fluid is output through the oral cavity 7 to provide additional power. Figures 1 to 5 As shown, the fluid delivery device mainly includes a housing 1 , a nose piece 2 , a mouth piece 7 , a supply unit 3 , a loading mechanism 4 , an actuating unit 5 and a valve unit 6 .

[0074] Among them, the shell 1, the nasal holder 2, the supply unit 3, the loading unit and the actuating unit 5 can be arranged with reference to the single-power nasal sprayer, which will not be repeated here.

[0075] The mouthpiece 7 is arranged on the housing 1 and is sealed to the housing 1. When in use, the mouthpiece 7 is placed on the user's mouth, so that the user can output the first fluid through the mouthpiece 7. The first fluid is the oral gas from the user's mouth, thereby providing power to assist the delivery of the second fluid.

[0076] The valve unit 6 is arranged in the flow passage connecting the mouthpiece 7 and the nosepiece 2 ( Figure 5 The arrow in the middle shows the complete flow channel), and is preferably arranged at one end of the flow channel close to the mouthpiece 7. The valve unit 6 has two main functions: on the one hand, it locks the supply unit 3 in the first position to achieve the function of preventing misoperation; on the other hand, it cooperates with the second fluid to provide constant power assistance to optimize the drug administration operation.

[0077] See also Figure 2 and Figure 3 As shown, in the fluid delivery device (dual-power nasal sprayer), in the initial state, the valve unit 6 cuts off the flow path and locks the supply unit 3 in the first position. It should be noted that the valve unit 6 here also indirectly locks the supply unit 3 in the first position by snap-fitting through the loading mechanism 4, so that it cannot be triggered to spray, thereby preventing waste and pollution caused by misoperation.

[0078] And due to the cut-off effect of the valve unit 6 itself, most of the flow channels in the shell 1 are in a closed state, and external gas cannot enter the shell 1, so it has a good dust-proof effect, can effectively prevent flow channel pollution, and improve the cleanliness and sanitary quality of the device.

[0079] When the pressure of the first fluid reaches the preset pressure, the pressure of the first fluid will drive the valve unit 6 to unlock, so that the supply unit 3 moves to the second position under the driving force of the loading force and outputs the second fluid, and at the same time, the flow channel is connected so that the first fluid can provide constant power assistance to the second fluid. This makes the device spray more powerful and stronger, making it easier to deliver and settle the drug in the nasal vestibule, and when the user outputs the first fluid, the soft palate connecting the oral cavity and the nasal cavity is closed, which will avoid adverse reactions or drug degradation caused by some drugs entering the esophagus through the nasal cavity.

[0080] Figures 3 to 5 The flow process of the valve unit 6 is shown, and the flow channel part is introduced first. In this embodiment, the flow channel includes an air storage chamber 8, which is a fan-shaped structure and is provided with an inlet 81 and an outlet 82. Among them, the mouthpiece 7 is sealed and connected to the inlet 81, and the valve unit 6 is rotatably arranged between the inlet 81 and the outlet 82. The valve unit 6 is configured as an air-driven control member, which can selectively control the opening and closing state of the outlet 82 according to the pressure of the first fluid. In short, the valve unit 6 has two deflection strokes: in the first deflection stroke, the outlet 82 is closed, and the first fluid enters the air storage chamber 8 from the inlet 81 and continues to accumulate; in the second deflection stroke, the outlet 82 is opened, and the first fluid flows rapidly from the air storage chamber 8 to the nosepiece 2.

[0081] As an example, a first arc surface 83 is provided on one side of the inlet 81, and a second arc surface 84 and a third arc surface 85 are provided on both sides of the outlet 82. The first arc surface 83 is arranged concentrically with the second arc surface 84, and the arc length of the first arc surface 83 is greater than the arc length of the second arc surface 84. The valve unit 6 is rotatably arranged at the arc center of the air storage chamber 8, and the valve unit 6 includes a first rotating part 61, a second rotating part 62 and a third rotating part 63. The first rotating part 61 is always in sealing cooperation with the first arc surface 83, and the third rotating part 63 is always in sealing cooperation with the third arc surface 85, so as to ensure the sealing of the valve unit 6 during the operation. However, in the first deflection stroke, the valve unit 6 is affected by the first fluid continuously input, and the second rotating part 62 and the second arc surface 84 will turn from the sealing cooperation to the sealing critical point, and in the second deflection stroke, the second rotating part 62 and the second arc surface 84 will turn from the sealing critical point to form a gap. At this time, the first fluid reaching the preset pressure will quickly flow from the notch to the nose piece 2, providing constant power assistance, while the valve unit 6 is unlocked and separated from the loading mechanism 4, and the supply unit 3 quickly moves to the second position and outputs the second fluid, which is mixed with the first fluid and delivered to the user's nose through the nose piece 2. The cooperation between the valve unit 6 and the loading mechanism 4 will be described later.

[0082] It should be emphasized that in this device, since the force driving the valve unit 6 to separate from the loading mechanism 4 is constant, that is, only when the pressure of the first fluid reaches the constant force, that is, the preset pressure, the valve unit 6 will unlock the supply unit 3 from the first position and open the flow channel, which makes the blowing force of the first fluid flowing to the nose piece 2 always constant and controllable, and the power assistance constituted by the blowing force is very stable, and there is no fluctuation. Compared with conventional dual-power nasal sprayers, the design of regulating the blowing force of the first fluid by the valve unit 6 in this application makes the depth of drug delivery to the nose close to the same each time, which is conducive to precise treatment.

[0083] Furthermore, the air storage chamber 8 is also provided with an air hole 86, so that during the resetting process of the valve unit 6 (the valve unit 6 is provided with a resetting torsion spring at the rotating part), air is introduced through the air hole 86 to balance the internal and external air pressures of the air storage chamber 8, thereby ensuring the smooth resetting of the valve unit 6. Figure 2 As shown, in some embodiments, the housing 1 includes a first half shell 11 and a second half shell 12 that are arranged opposite to each other. The first half shell 11 and the second half shell 12 can be arranged opposite to each other up and down or left and right, and the two can be detachably connected and fixed, so that the user can replace the supply unit 3 under the guidance of medical staff, thereby reducing the cost of use. Of course, in some other embodiments, the housing 1 after the first half shell 11 and the second half shell 12 are combined can also be non-detachable, so that the device becomes a disposable device.

[0084] See also Figures 3 to 7 and Fig.10 As shown, in some embodiments, the supply unit 3 includes a nozzle 31, a pump assembly 32 and a fluid container 33. The fluid container 33 may be a bottle structure, which is used to store the second fluid. The pump assembly 32 may be a mechanical infusion pump or a powder delivery pump, which is used to deliver a prescribed dose of the second fluid from the fluid container 33 to the nozzle 31. The nozzle 31 is disposed in the nosepiece 2, protected by the nosepiece 2, and is used to convert the second fluid into a spray or a jet, thereby increasing the contact area between the drug and the nose and improving the treatment effect.

[0085] Furthermore, an annular channel 21 is formed between the nozzle 31 and the nose piece 2, and the annular diameter of at least part of the annular channel 21 gradually decreases along the delivery direction of the second fluid, so that the first fluid is squeezed when passing through the annular channel 21 and the flow rate is accelerated in the area with a smaller annular diameter, thereby enhancing the power assist effect of the first fluid.

[0086] Furthermore, a through hole 321 is provided on the pump assembly 32, and the through hole 321 is connected to the fluid container 33 to balance the internal and external air pressures of the fluid container 33, thereby ensuring that the normal output of the pump assembly 32 is not affected.

[0087] See also Figures 3 to 7As shown, in some embodiments, the loading mechanism 4 includes a first cylinder 41 , the first cylinder 41 is sleeved on the bottom of the supply unit 3 , and the supply unit 3 is locked in the first position by the first cylinder 41 .

[0088] See Figure 3 and Fig. 9 As shown, a locking tongue 411 is provided at the top of the first tube 41. The locking tongue 411 is generally in an inclined triangular structure, including a first locking surface 4111 and a first guide surface 4112. Correspondingly, a locking protrusion 64 is provided on the valve unit 6 to cooperate with the locking tongue 411. The locking protrusion 64 has a second locking surface 641 inclined downward, and a second guide surface 642 is provided on the outer side of the locking protrusion 64 above the second locking surface 641.

[0089] In the initial state, the locking tongue 411 is locked into the locking protrusion 64 by the loading force, the first locking surface 4111 and the second locking surface 641 are locked with each other, the position of the first tube 41 is restricted, and the supply unit 3 is locked in the first position. Figure 4 As shown, as the first fluid drives the valve unit 6 to rotate to the second deflection stroke, the second locking surface 641 gradually separates from the first locking surface 4111. Under the action of the pre-applied loading force, the first tube 41 moves upward to drive the supply unit 3 to move from the first position to the second position to output the second fluid, which is the action of drug spraying. When the user cancels the loading force, for example, after releasing the grip on the actuating unit 5, the supply unit 3 can be reset to the first position. During this process, the first guide surface 4112 moves along the second guide surface 642, so that the locking tongue 411 is re-engaged in the locking protrusion 64 and restored to the initial state.

[0090] In addition, the loading mechanism 4 further includes a second tube 42 and an elastic member 43 .

[0091] The second tube 42 is sleeved on the bottom of the first tube 41, and the two are slidably matched. Note that there should be a certain gap between the second tube 42 and the first tube 41 to prevent the first tube 41 from moving away from the second tube 42 to generate negative pressure adsorption and weaken the loading force.

[0092] The elastic member 43 is disposed between the first tube 41 and the second tube 42. For example, the elastic member 43 may be a spring, and a spring seat is provided below the first tube 41 and at the inner bottom of the second tube 42. Both ends of the spring are clamped on the two spring seats. The second tube 42 can be operated to move toward the first tube 41 to compress the elastic member 43 to obtain a loading force. For example, the second tube 42 can be driven to move toward the first tube 41 by operating the actuating unit 5. See the following description for details.

[0093] Furthermore, a stopper 412 is provided in the middle of the first cylinder 41. As an example, there are two stoppers 412, which are symmetrically distributed on both sides of the first cylinder 41 to improve the stability of the movement of the first cylinder 41. Correspondingly, a limiting groove 421 is provided on the inner wall of the second cylinder 42, and the length direction of the limiting groove 421 is parallel to the longitudinal axis direction of the device. By slidingly matching the stopper 412 with the limiting groove 421, the first cylinder 41 and the second cylinder 42 are prevented from being separated or the locking tongue 411 on the first cylinder 41 is hit to cause the loading mechanism 4 structure to be damaged.

[0094] Furthermore, a seal 9 is provided between the inner wall of the housing 1 and the second tube 42 to keep the inner wall of the housing 1 and the loading mechanism 4 sealed, thereby preventing leakage of the first fluid and ensuring that the strength of the power assist is not affected. Exemplarily, the seal 9 can be a sealing ring, and the inner wall of the housing 1 is provided with a sealing groove 14, the sealing ring is installed in the sealing groove 14, and is always sealed with the outer periphery of the second tube 42.

[0095] Furthermore, the inner wall of the housing 1 is provided with a guide groove 15, the length direction of which is parallel to the longitudinal axis of the device. Correspondingly, a slider 422 is also provided on the outer side of the second cylinder 42, and the slider 422 is slidably arranged in the guide groove 15, thereby improving the stability of the movement of the second cylinder 42 through the guiding effect.

[0096] In some embodiments, the deflection angle of the actuating unit 5 is 30°-60°, and preferably 30°-40°, so as to facilitate the user's gripping operation.

[0097] See also Figure 2 and Figure 8 As shown, in some embodiments, the actuating unit 5 includes a pressing portion 51 and a connecting portion 52 .

[0098] The pressing portion 51 is generally a trapezoidal structure, one end of the pressing portion 51, for example, the upper end, is rotatably connected to the inside of the housing 1 (a reset torsion spring is provided at the rotation point of the pressing portion 51), and the pressing portion 51 at least partially protrudes from the outer contour of the housing 1. In addition, the surface of the pressing portion 51 may be provided with anti-slip grooves to increase friction with the user's hand.

[0099] The connecting portion 52 extends from the pressing portion 51 into the housing 1. As an example, there are two connecting portions 52, which are symmetrically distributed on both sides of the pressing direction of the pressing portion 51 to improve the balance of the actuation force, and the connecting portion 52 can be integrally formed with the pressing portion 51. The connecting portion 52 is provided with a guide groove 521, and correspondingly, a driven block 423 matching the guide groove 521 is provided on the outer side of the second cylinder 42 of the loading mechanism 4. When the user squeezes the pressing portion 51, the connecting portion 52 drives the driven block 423 to move through the guide groove 521, so that the second cylinder 42 moves along the longitudinal axis of the device, and the loading force is formed by squeezing the elastic member 43.

[0100] Furthermore, the guide slot 521 includes an inclined driving section 5211 and an anti-slip section 5212 connecting the two ends of the driving section 5211. During the actuation process, as the guide slot 521 moves toward the inside of the housing 1, the driving section 5211 can drive the driven block 423 to move upward, thereby driving the second cylinder 42 to move toward the first cylinder 41. After the actuation force is withdrawn, during the resetting process of the pressing portion 51, the anti-slip section 5212 can prevent the driving section 5211 from being detached from the driven block 423, thereby avoiding affecting the next actuation operation.

[0101] See also Figures 1 to 5 As shown, in some embodiments, the angle between the nose piece 2 and the mouth piece 7 is 30°-70°, and the preferred angle is 35°-45° to facilitate user operation.

[0102] In some embodiments, an antibacterial layer (not shown) is provided on the inner wall of the mouthpiece 7 and / or the nosepiece 2 to prevent or reduce the growth of microorganisms and ensure healthy and safe use. Exemplarily, the antibacterial layer can be a healthy and non-toxic coating such as a titanium dioxide layer, an antibacterial polymer layer, or an antibacterial nano-coating. Preferably, the antibacterial layer in the present application is a nano-silver layer, and the silver ions released by the nano-silver layer have a certain killing effect on bacteria, fungi and viruses, which can prevent the growth and spread of microorganisms inside the mouthpiece 7 and / or the nosepiece 2. In addition, the nano-silver layer has good electrical conductivity. When the mouthpiece 7 and / or the nosepiece 2 contacts the human body, the static electricity generated during the use of the device can be guided to the ground through the human body, thereby realizing the function of removing static electricity and avoiding the influence of static adsorption on the delivery process of drug delivery.

[0103] See also Figures 1 to 5 As shown, the present invention also discloses a method for delivering fluid to the nasal airway of a user, which method is applicable to the above-mentioned dual-power nasal sprayer and includes steps S1 to S5.

[0104] S1. Provide a fluid delivery device, which includes a nosepiece 2, a mouthpiece 7, a supply unit 3, a loading unit, an actuation unit 5 and a valve unit 6.

[0105] S2. Apply a loading force to the supply unit 3 of the fluid delivery device and lock it in the first position. Specifically, the user can squeeze the actuation unit 5 to make the loading mechanism 4 apply a loading force to the supply unit 3, and the valve unit 6 cooperates with the loading mechanism 4 to lock the supply unit 3 in the first position.

[0106] S3. The nose piece 2 and the mouth piece 7 of the fluid delivery device are respectively placed on the nose and mouth of the user. Specifically, the nose piece 2 can be inserted into the nose of the user to a depth of not less than 2 cm to improve the sealing between the nose piece 2 and the nose of the user and ensure the delivery depth of the drug. The mouth piece 7 is held in the mouth of the user, and it is noted that the patency of the mouth piece 7 is not damaged.

[0107] S4, the user outputs the first fluid through the mouthpiece 7, and the supply unit 3 is unlocked from the first position by the pressure of the first fluid. Specifically, as the first fluid is continuously output, the valve unit 6 is driven to deflect, and the locking protrusion 64 on the valve unit 6 gradually separates from the locking tongue 411 on the loading mechanism 4, until the locking protrusion 64 is completely separated from the locking tongue 411, at which time the supply unit 3 is unlocked from the first position.

[0108] S5, the supply unit 3 moves to the second position, and delivers the second fluid to the nasal airway through the nasal piece 2, and at the same time, the first fluid flows toward the nasal piece 2 and provides constant power assistance to the second fluid. Specifically, since the actuating unit 5 is always in a gripped state, the loading force applied by the loading mechanism 4 always acts on the supply unit 3. At the moment of unlocking, the loading force is released to drive the supply unit 3 to move to the second position to output the second fluid, and at the same time, the valve unit 6 also conducts the flow channel, causing the first fluid to flow toward the nasal piece 2 to provide constant power assistance for the delivery of the second fluid.

[0109] In the above method, the fluid delivery device is configured to provide an actuation performance of 0.8 L / min when the user outputs a first fluid pressure of at least 3 kPa. The actuation performance refers to the performance of promoting the flow of the second fluid, which is the so-called auxiliary power. In this application, it can be a constant value of 0.8 L / min, so as to ensure that the delivery stroke of the device is nearly consistent each time.

[0110] At a pressure of 3 kPa, at least 85% of the first fluid in the mouthpiece 7 flows to the nosepiece 2 to provide sufficient auxiliary power and ensure the drug delivery effect. The pressure of 3 kPa is the opening force of the valve unit 6. Below this pressure, the valve unit 6 cuts off the flow channel. Only when the pressure of the first fluid is greater than or equal to 3 kPa, the valve unit 6 can be driven to open to provide auxiliary power, thereby achieving the function of preventing misoperation.

[0111] Furthermore, the supply unit 3 provides the delivery of the second fluid within less than 120ms after unlocking, preferably within less than 80ms after unlocking, more preferably within less than 50ms after unlocking, and even more preferably within less than 10ms after unlocking, so that the second fluid can form an explosive spray with the first fluid that flows in instantly. Moreover, the actuation performance of 0.8L / min will hardly change in this extremely short time, and the triggering force of the supply unit 3 is constant, which ultimately enables the drug delivery stroke to be precisely controlled.

[0112] Further, the spray angle of the fluid delivery device in the sagittal plane is not less than 35°, for example, the spray angle in the sagittal plane may be 40°, 45°, 50°, etc. And / or, the spray angle of the fluid delivery device in the vertical sagittal plane is not greater than 30°, for example, the spray angle in the vertical sagittal plane may be 25°, 20°, 15°, etc. By limiting the spray angle of the device in the sagittal plane and / or the vertical sagittal plane, the spray state can be improved and the treatment effect can be enhanced.

[0113] It should be noted that the above method adopts a mode of pressing first and then blowing, that is, the user first squeezes the actuator to make the loading mechanism 4 apply a loading force to the supply unit 3 locked in the first position, and then blows in gas to make the valve unit 6 synchronously complete the unlocking position and the function of conducting the fluid. This design makes the blowing force of the first fluid always constant and controllable. Compared with the conventional dual-power nasal spray mode of blowing first and then pressing / blowing and pressing synchronously, the method of the present application accumulates gas in the gas storage chamber, and can only output power assistance after the gas pressure reaches the preset pressure, and uses blowing to unlock the restriction to output the drug synchronously. This method is compatible with all people, simple to operate, and the blowing force of the first fluid is controllable. The depth of drug delivery to the nose is nearly consistent each time, which is more conducive to precise treatment.

[0114] In addition, before unlocking by blowing force, no matter whether the actuating unit 5 is operated or not, the supply unit 3 has no possibility of triggering the injection, thus realizing the function of preventing misoperation; during this period, the valve unit 6 cuts off the flow channel and also plays a dust-proof role, thereby improving the cleanliness and hygienic quality inside the device.

[0115] After being unlocked by the blowing force, the loading force can instantly trigger the supply unit 3, so that the pump assembly 32 delivers the second fluid to a farther position, thereby effectively increasing the drug delivery depth.

[0116] In some embodiments, the end of the nose piece 2 close to the user's nose is tapered. The nose piece 2 with a tapered structure can adapt to the noses of different users and keep it centered after being inserted into the nose, thereby reducing the collision between the second fluid and the nasal airway and improving the delivery effect.

[0117] In some embodiments, during step S4 to step S5, the user's soft palate is in a closed state, which can prevent adverse reactions or drug degradation caused by some drugs entering the esophagus through the nasal cavity, thereby improving the treatment effect.

[0118] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations on the present invention. A person skilled in the art may change, modify, substitute and modify the above embodiments within the scope of the invention without departing from the principles and purpose of the present invention. All such changes should fall within the scope of protection of the claims of the present invention.

Claims

1. A fluid delivery device, characterized in that include: case; A mouthpiece and a nosepiece are arranged on the shell, wherein the mouthpiece is used to output a first fluid, and a flow channel is arranged between the mouthpiece and the nosepiece, the flow channel includes an air storage cavity, and the air storage cavity is a fan-shaped structure and is provided with an inlet and an outlet; A supply unit, disposed in the housing, wherein the supply unit stores a second fluid; A loading mechanism, disposed below the supply unit, and configured to apply a loading force to the supply unit; A valve unit is rotatably disposed at the arc center of the gas storage chamber. In an initial state, the valve unit cuts off the flow channel and engages with the loading mechanism to lock the supply unit in the first position; The valve unit comprises a first rotating part, a second rotating part and a third rotating part, and the valve unit has two deflection strokes: in the first deflection stroke, the outlet is closed, and the first fluid enters the air storage chamber from the inlet and continues to accumulate; in the second deflection stroke, the outlet is opened, and the first fluid quickly flows from the air storage chamber to the nasal bearing; The delivery operation method of the fluid delivery device comprises: S1, applying a loading force to the supply unit through the loading mechanism, and locking it in a first position in cooperation with the valve unit; S2, placing the nose piece and the mouth piece on the user's nose and mouth respectively; S3, outputting the first fluid through the mouthpiece, and when the pressure of the first fluid reaches a preset pressure, the valve unit deflects the flow channel and separates from the loading mechanism, so that the supply unit is unlocked from the first position; S4. The supply unit moves to the second position under the action of the loading force, so that the second fluid is delivered to the nasal airway through the nasal holder, and at the same time the first fluid flows to the nasal holder through the flow channel and provides constant power assistance to the second fluid.

2. The fluid delivery device according to claim 1, characterized in that The nose piece (2) extends into the nose by at least 2 cm.

3. The fluid delivery device according to claim 1, characterized in that One end of the nose piece (2) is tapered.

4. The fluid delivery device according to claim 1, characterized in that The fluid delivery device further comprises an actuation unit (5); The actuating unit (5) is connected to the loading mechanism (4), and by operating the actuating unit (5), the loading mechanism (4) can be driven to apply a loading force to the supply unit (3) in advance.

5. The fluid delivery device according to claim 4, characterized in that When the first fluid is input into the mouthpiece (7), the actuating unit (5) is always in a squeezed state.

6. The fluid delivery device according to claim 1, characterized in that The first fluid is a mouth-blown gas; The second fluid is a powdery substance, a granular substance or a liquid substance, and the second fluid is delivered in the form of a spray or a jet.

7. The fluid delivery device according to any one of claims 1 to 6, characterized in that: The fluid delivery device is configured to provide an actuation performance of 0.8 L / min when a first fluid pressure of 3 kPa-6 kPa is input.

8. The fluid delivery device according to claim 7, characterized in that At a pressure of 3 kPa, at least 85% of the first fluid in the mouthpiece (7) flows toward the nosepiece (2).

9. The fluid delivery device according to any one of claims 1 to 6, characterized in that: The supply unit provides delivery of the second fluid in less than 120 ms from unlocking.

10. The fluid delivery device according to any one of claims 1 to 6, characterized in that: The fluid delivery device has a spray angle of not less than 35° in the sagittal plane; and / or, The fluid delivery device has a spray angle of no greater than 30° in the vertical sagittal plane.

Images