Pulse detection device and method based on digital holography

Abstract

The invention discloses a pulse detection device and method based on digital holography, and belongs to the technical field of digital holography. The device comprises a coherent light source laser, a beam splitter, a beam expander, a pinhole filter, a Fourier lens, an image acquisition device CCD (Charge Coupled Device), an optical path compensator, a total reflective mirror, an optical power attenuator, a window and a movable pulse pillow, wherein the whole device is fixed in an upper cassette and a lower cassette. Wherein the optical path compensation device, the optical power attenuator and the image acquisition device CCD are connected with the computer. The digital holographic technology is used for pulse detection, the three-dimensional beating condition of the pulse at the radial artery can be detected in a non-contact and high-precision mode, the detected pulse three-dimensional shape is applied to pulse detection and traditional Chinese medicine pulse condition analysis, and the accuracy of pulse detection and the objectivity of pulse condition diagnosis can be greatly improved.

Description

Technical Field

[0001] The invention relates to a pulse detection device and method based on digital holography, belonging to the technical field of digital holography. Background Art

[0002] Pulse measurement is an important method to evaluate the health of the human cardiovascular system. The pressure wave generated in the blood vessels by the heart's pumping is called the pulse wave. The pulse wave carries a lot of information about the cardiovascular state. We can analyze this information to make a preliminary diagnosis of the cardiovascular health state. When the human pulse is in a quiet state, the pulse of an adult is 60-100 beats / minute, and the pulse of a child or newborn can be faster, reaching 110-140 beats / minute.

[0003] Pulse diagnosis is a non-invasive diagnostic method in traditional Chinese medicine. It obtains information about the patient's health status by feeling the pulse of the patient's radial artery. Through the changes in the pulse, traditional Chinese medicine can determine the disease the patient may have; it can understand the development and outcome of the disease. It is an important part of the "cut" in "look, smell, ask, and feel" in traditional Chinese medicine. The pulse theory of traditional Chinese medicine divides the pulse into 6 categories and a total of 28 types according to the characteristics of different pulses. The main pulse characteristics include pulse size, hardness, speed, evenness, and floating pulse. These pulse characteristics can represent some health conditions, but because each doctor's level is uneven, the diagnosis of patients is often based on experience and subjective feelings, and it is inevitable that the analysis of the patient's condition will be inaccurate and subjective.

[0004] At present, the main methods for pulse detection are palpation, auscultation, electrocardiogram, and photoplethysmography. Among them, palpation and auscultation rely more on the doctor's judgment and are prone to misjudgment; the latter two require the measuring device to be close to the patient, which is easy to cause discomfort to the patient, and neither can achieve non-contact detection.

[0005] At present, the automatic and intelligent identification of the collection position in non-contact heart rate monitoring technology is mainly determined by using the two-dimensional image of the radial artery. Although certain achievements and progress have been made, there are still many shortcomings.

[0006] Since the deformation of the skin caused by the pulse beating at the radial artery is very small, only the frequency of the pulse can be obtained, and it is difficult to obtain the amplitude of the pulse; when using ordinary photography technology, the pulse signal obtained is often of poor quality and low signal-to-noise ratio, making it difficult to accurately analyze; the existing technology lacks a non-contact method that can accurately obtain the patient's pulse information; therefore, there is an urgent need for a method and device that can objectively and accurately analyze the patient's pulse. Summary of the invention

[0007] In order to solve the above problems, the present invention introduces digital holography technology into pulse detection; the present invention provides a pulse detection device and method based on digital holography, which makes up for the deficiency of the prior art that only pulse frequency can be detected but pulse amplitude cannot be measured; at the same time, it also makes up for the defect that the analysis of patient's pulse is not objective and accurate enough due to the difference of subjective feelings of doctors in traditional Chinese medicine pulse diagnosis, and realizes the acquisition and analysis of patient's pulse information in a contactless way.

[0008] To achieve the above objectives, the present invention combines the characteristics of digital holography that can accurately measure tiny vibrations, introduces digital holography technology into pulse detection, and can achieve non-contact detection while ensuring non-invasive detection; the present invention adopts a reflective holographic method to capture and record information at the radial artery of the human arm, and further analyzes the acquired information to obtain the amplitude, frequency and three-dimensional morphology of the pulse.

[0009] In order to achieve the above technical requirements, the technical solution adopted by the present invention is as follows:

[0010] A pulse detection device based on digital holography comprises an upper dark box and a lower dark box. The upper dark box is provided with: a coherent light source laser, a beam splitter I, a beam expander I, a pinhole filter I, a Fourier lens I, a beam splitter II, an image acquisition device CCD, an optical path compensator, a total reflection mirror, a beam expander II, a Fourier lens II, a pinhole filter II, an arm of a patient to be tested, and an optical power attenuator. A window is provided in the partition between the upper and lower dark boxes; the lower dark box is provided with a movable pulse pillow, and the movable pulse pillow is located below the window; the upper dark box 19 is connected to the lower dark box 20, and a light-shielding curtain is provided at the hole of the lower dark box.

[0011] The image acquisition device CCD, optical path compensator, and optical power attenuator are connected to a computer. After adjusting the optical path compensator and optical power attenuator through computer processing to achieve the best imaging effect, the pulse at the radial artery is recorded, and the recorded pulse information is processed to obtain information such as pulse amplitude, frequency, pulse waveform, and three-dimensional morphology of pulse vibration.

[0012] The laser emitted by the coherent light source laser is divided into two beams after passing through beam splitter I. One beam passes through the optical path compensator, optical power attenuator, beam expander I, pinhole filter I, and Fourier lens I to form a parallel beam, which is the reference light; the other beam is adjusted by the reflector, and then passes through beam expander II, pinhole filter II, and Fourier lens II to form a parallel beam, which is then irradiated to the surface of the area to be measured through the window and then reflected. The reflected speckle field passes through the window and falls on beam splitter II, which is the object light. The object light and the reference light form interference fringes at beam splitter II, which are received by the image acquisition device CCD; the collected information is then transmitted to the computer for processing, and finally the computer completes the analysis and reproduction process and displays the measurement results.

[0013] The present invention adopts a pinhole filter to eliminate the influence of stray light on the optical path, so as to improve the imaging quality. In the process of holographic imaging, the optical path difference between the object light and the reference light needs to be within the coherence length of the coherent light source laser to form an image. For the target detected by the present invention, the radial artery of the arm detected is a moving target. Therefore, the present invention sets a movable pulse pillow in the dark box in the lower half of the test device. The pulse pillow can ensure that when measuring different targets, the measured target is moved and fixed at a position with good imaging effect to ensure the imaging requirements. The present invention sets an optical power attenuator and an optical path compensation device in the upper dark box, which cooperate with the movable pulse pillow to modulate the reference optical path and light intensity of different measured targets.

[0014] The device of the present invention can simultaneously measure the following three indicators during the detection process: the vibration amplitude of the pulse of the detected object, the vibration frequency of the pulse of the detected object, and the dynamic three-dimensional shape formed by the pulse beating in the measured area during the detection period.

[0015] The coherent light source laser is a 632.8 nm continuous laser.

[0016] The working bands of the beam splitter I, beam expander I, Fourier lens I, beam splitter II, image acquisition device CCD, optical path compensator, total reflection mirror, beam expander II, Fourier lens II, window and optical power attenuator in the device all correspond to the 632.8nm laser band.

[0017] After the arm is placed on the dark box, a shading cloth needs to be used for shading during the measurement process.

[0018] The dark box should be made of a material with greater hardness and better stability to provide sufficient stability while protecting the internal device.

[0019] The dark box should be placed on a stable platform when working, and its stability should be ensured as much as possible.

[0020] The beam splitter has a splitting ratio of 1:1 or 1:2.

[0021] The optical path compensator is controlled by a computer so that the optical paths of the reference light and the object light are substantially the same.

[0022] The optical power attenuator is controlled by a computer so that the light intensities of the reference light and the object light are substantially the same.

[0023] The radial artery position where the pulse is detected is adjusted by a movable pulse pillow so that the area to be detected is located at a suitable position, and the arm to be detected is fixed by the movable pulse pillow to prevent nerve impulses and muscle contractions on the arm from affecting the detection process.

[0024] The movable pulse pillow can be adjusted in position up and down, left and right, and front and back.

[0025] When the movable pulse pillow is used to fix the arm, the force should be moderate and the arm should not be pressed too much to cause inaccurate detection.

[0026] The inner wall of the upper part of the dark box is pure black to prevent light from being reflected back and forth inside the opaque dark box and being received by the image acquisition device CCD, thereby affecting the image acquisition device CCD's reception of the interference fringe pattern.

[0027] The present invention provides a pulse detection method based on digital holography technology, which uses the above device to perform pulse detection. The specific steps of the detection method are as follows:

[0028] S1: Place and fix the arm on the movable pulse pillow and turn on the light source laser.

[0029] S2: Adjust the optical power attenuator and optical path compensator, and adjust the position of the movable pulse pillow to make the light intensity and optical path of the reference light and the object light basically consistent, so that the device can obtain a hologram with good imaging.

[0030] S3: Use the image collector CCD to collect the hologram and transfer the hologram to the computer for storage.

[0031] S4: The first hologram acquired by the image acquisition device CCD is called the initial deformation field hologram. The initial deformation field hologram is digitally reproduced in the computer through a reproduction program to obtain an initial deformation complex light field.

[0032] S5: The hologram subsequently acquired by the image collector CCD is called a changed deformation field hologram. The changed deformation field hologram is digitally reproduced in a computer through a reproduction program to obtain a changed deformation complex light field.

[0033] S6: numerically divide the corresponding points of the initial deformed complex light field and the deformed complex light field after the change, and take the phase angle of the complex light field after the division to obtain the wrapped phase of the deformed field after the change.

[0034] S7: Unwrapping the changed deformation field wrapped phase to obtain the deformation of the skin surface caused by the pulse beating at the radial artery.

[0035] S8: The deformation of the pulse is recorded by computer software, and the difference between the highest point and the lowest point of the vibration amplitude is calculated, that is, the vibration amplitude of the pulse is obtained.

[0036] S9: Draw a waveform diagram of the pulse vibration amplitude change period through computer software, and calculate the pulse vibration frequency.

[0037] S10: Correlate the three-dimensional pulse images at each moment to obtain a dynamic three-dimensional appearance of the pulse vibration.

[0038] S11: Monitor and judge the pulse deformation through computer software and output a diagnosis report, including: pulse vibration frequency, vibration amplitude, waveform, dynamic three-dimensional morphology.

[0039] Furthermore, before the measurement begins, the position of the movable occipital is adjusted according to the thickness of the arm of the subject so that the device of the present invention can obtain good detection results.

[0040] Furthermore, the present invention adjusts the optical power attenuator and the optical path compensation device by computer before the measurement starts so that the device of the present invention can obtain good detection results.

[0041] Furthermore, during the test, silicone oil may be applied to the area of ​​the patient's radial artery to be tested to increase the reflection efficiency of the skin, so as to obtain a good test result.

[0042] Furthermore, during the test, the surrounding environment needs to be quiet and stable, and the patient being tested needs to remain calm and relaxed to avoid additional nerve impulses and muscle contractions that may affect the test.

[0043] Furthermore, when the movable pulse pillow is used to fix the arm, the force should be moderate and the arm should not be pressed too much to cause inaccurate detection.

[0044] Furthermore, the hologram reconstruction method uses Fresnel diffraction calculations.

[0045] Furthermore, the unwrapping method is a least squares unwrapping method or other path-independent phase unwrapping method.

[0046] Furthermore, the pulse vibration frequency is the number of pulse beats per minute, based on the point at the lower part of the radial artery of the wrist where the pulse is most obvious, and is counted from the first minimum deformation of the skin surface to the second minimum.

[0047] Furthermore, the pulse vibration amplitude is an average value of multiple maximum differences in skin surface deformation.

[0048] Furthermore, the collected data has high requirements on computing resources, and it should be ensured that the processing power of the computer can meet this demand.

[0049] Beneficial effects of the present invention:

[0050] (1) The present invention is based on the principle of digital holography, uses the interference phenomenon of light waves to obtain information, and performs computational analysis on the image to obtain a waveform diagram of the pulse vibration in the measurement area. After analyzing it, information such as heart rate and heart rhythm can be obtained, and the entire process is non-invasive and contactless.

[0051] (2) Holographic technology can be used to record and reproduce the three-dimensional information of an object. After computer processing, a three-dimensional dynamic image of the pulse vibration on the skin surface can be obtained. Holographic measurement has high accuracy and the accuracy of detecting the pulse vibration amplitude can reach the wavelength level. The specific accuracy is related to the wavelength of the coherent light source laser used.

[0052] (3) The present invention detects the vibration of the skin surface by recording the reflected light from the skin surface, so it is less affected by skin color. Since holographic measurement obtains three-dimensional information, including intensity and phase, the amplitude and frequency of the pulse can be calculated from it. The present invention associates the detected holographic reconstructed images to form a three-dimensional dynamic image, which can clearly observe the pulse beating in the detected area and can use traditional Chinese medicine to perform a preliminary pulse analysis.

[0053] (4) The present invention is provided with a movable pulse pillow, which can be adjusted to suit different detection objects; the entire device of the present invention is protected and fixed by a dark box, and the inner side of the side wall of the dark box used is pure black. Only a window position is left on the device to facilitate the transmission of the experimental light beam, so as to avoid interference from ambient visible light and improve the phase acquisition accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0054] Figure 1 It is the internal structure diagram of the dark box of the present invention;

[0055] Figure 2 is an external three-dimensional diagram of the device of the present invention;

[0056] Figure 3 It is a schematic diagram of the working of the movable pulse pillow in the device of the present invention;

[0057] Figure 4 It is a schematic diagram of the flow chart of the detection method of the device of the present invention.

[0058] In the figure: 1-coherent light source laser; 2-beam splitter I; 3-beam expander I; 4-pinhole filter I; 5-Fourier lens; 6-beam splitter II; 7-image acquisition device CCD; 8-optical path compensator; 9-total reflection mirror; 10-beam expander II; 11-Fourier lens II; 12-pinhole filter II; 13-movable pulse pillow; 14-arm of the patient to be tested; 15-window; 16-optical power attenuator; 17-hole, 18-computer; 19-upper part dark box; 20-lower part dark box; 21-movable platform; 22-fixed splint; 23-guide rail. DETAILED DESCRIPTION

[0059] The following will be combined with the drawings in the embodiments of the present disclosure to clearly and completely describe the technical solutions in the embodiments of the present disclosure. Obviously, the described embodiments are part of the embodiments of the present disclosure, rather than all of the embodiments. Based on the embodiments in the present disclosure, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present disclosure.

[0060] Example 1

[0061] like Figures 1 to 3 As shown, the present embodiment provides a pulse detection device based on digital holography, including an upper dark box 19 and a lower dark box 20, wherein the upper dark box 19 is provided with: a coherent light source laser 1, a beam splitter Ⅰ2, a beam expander Ⅰ3, a pinhole filter Ⅰ4, a Fourier lens Ⅰ5, a beam splitter Ⅱ6, an image acquisition device CCD 7, an optical path compensator 8, a total reflection mirror 9, a beam expander Ⅱ10, a Fourier lens Ⅱ11, a pinhole filter Ⅱ12, and an optical power attenuator 16, and a window 15 is provided in the partition between the upper and lower dark boxes; the lower dark box is provided with a movable pulse pillow 13, and the pulse pillow is located below the window 15; the upper dark box 19 is connected to the lower dark box 20, and a shade curtain is provided at the hole 17 of the lower dark box 20, wherein the optical path compensator 8, the optical power attenuator 16, and the image acquisition device CCD7 are connected to the computer 18.

[0062] like Figure 1 , Figure 2 As shown, the device is placed on a stable platform. When starting measurement, the patient's arm is placed on the movable pulse pillow 13. The movable pulse pillow 13 moves according to the imaging requirements, and the patient's arm 14 to be measured is fixed on the movable pulse pillow 13 to prevent the patient's arm from sliding; turn on the coherent light source laser 1 to test the hologram imaging.

[0063] The laser emitted by the coherent light source laser 1 is divided into two beams after passing through the beam splitter Ⅰ2. One beam of light passes through the optical path compensator 8, the optical power attenuator 16, the beam expander Ⅰ3, the pinhole filter Ⅰ4, and the Fourier lens Ⅰ5 to form a parallel light beam, which is the reference light; the other beam of light is adjusted by the reflector 9, and then passes through the beam expander Ⅱ10, the pinhole filter Ⅱ12, and the Fourier lens Ⅱ11 to form a parallel light beam. This beam of light passes through the window 15 and irradiates the skin surface of the patient's arm 14. The reflected light beam passes through the window 15 and returns to the upper dark box 19 and falls on the beam splitter Ⅱ6. This light beam is the object light; at this time, the light beam already carries the phase information of the measurement area. This light beam interferes with the reference light at the beam splitter Ⅱ to form fringes, that is, the required hologram. These interference fringes are collected by the image acquisition device CCD and transmitted to the computer. This is the data recording process of the device.

[0064] During the recording process, the coherent light source laser and the image acquisition device CCD work continuously, recording 30 holograms of the patient's arm for 20 seconds; the collected holograms are used for phase reconstruction to obtain a three-dimensional image of the pulse beating in the measurement area, and the three-dimensional images in the measured time period are combined according to time to obtain a three-dimensional dynamic image of the pulse beating in the measurement area.

[0065] Example 2

[0066] like Figures 1 to 3 As shown, this embodiment provides a pulse detection method based on digital holography according to the detection device described in Embodiment 1, which specifically includes the following steps:

[0067] S1: Place and fix the arm on the movable pulse pillow and turn on the light source laser.

[0068] S2: Adjust the optical power attenuator and optical path compensator, and adjust the position of the movable pulse pillow to make the light intensity and optical path of the reference light and the object light basically consistent, so that the device can obtain a hologram with good imaging.

[0069] S3: Use the image collector CCD to collect the hologram and transfer the hologram to the computer for storage; this step takes 20 seconds and records 30 holograms per second.

[0070]

[0071] S4: The first hologram acquired by the image acquisition device CCD is called the initial deformation field hologram. The initial deformation field hologram is digitally reproduced in the computer through a reproduction program to obtain an initial deformation complex light field.

[0072] Where o0(x, y) is the amplitude of the initial deformed complex light field, j is an imaginary unit, and ф0(x, y) is the phase of the initial deformed complex light field.

[0073] S5: The hologram subsequently acquired by the image acquisition device CCD is called the changed deformation field hologram (recorded as time t), and the changed deformation field hologram is digitally reproduced in the computer through a reproduction program to obtain the deformation complex light field at the changed time t;

[0074]

[0075] Among them t (x, y) is the amplitude at time t, j is the imaginary unit, ф t (x, y) is the phase of the complex light field at time t.

[0076] S6: Divide the corresponding points of the initial deformed complex light field and the deformed complex light field after the change by numerical values ​​to obtain a new complex light field:

[0077]

[0078] And take the phase angle of the complex light field after the division to get the wrapped phase of the changed deformation field:

[0079]

[0080] S7: Unwrapping the changed deformation field wrapped phase to obtain the deformation of the skin surface caused by the pulse beating at the radial artery.

[0081] S8: The deformation of the pulse is recorded by computer software, and the difference between the highest point and the lowest point of the vibration amplitude is calculated, that is, the vibration amplitude of the pulse is obtained.

[0082] S9: Draw a waveform of the vibration amplitude of the pulse through computer software, establish a coordinate system with time as the horizontal axis and the vibration amplitude as the vertical axis, and draw a pulse waveform. When the deformation amount reaches the lowest point twice, it is recorded as one vibration, and the vibration frequency of the pulse is calculated.

[0083] S10: Correlate the three-dimensional pulse images at each moment to obtain a dynamic three-dimensional appearance of the pulse vibration.

[0084] S11: Monitor and judge the pulse deformation through computer software and output a diagnosis report, including: pulse vibration frequency, vibration amplitude, waveform, dynamic three-dimensional morphology.

[0085] Furthermore, the pulse information obtained includes: the pulse vibration frequency represents the heart rate; it represents the contractility of the heart, the fullness of blood vessels, the elasticity of the arterial wall, etc.; the pulse waveform reflects the changes in blood circulation and the state of cardiovascular function to a certain extent, and recording and analyzing the pulse graph can assist in the diagnosis of some cardiovascular diseases; the three-dimensional movement form of the radial artery is closely related to the formation and transformation of the median situation of traditional Chinese medicine pulse diagnosis, from which the health of the heart and other organs can be inferred.

[0086] Furthermore, when testing patients, they should be instructed on how to position their arms and ensure that they remain calm during the test to avoid nerve impulses and muscle contractions affecting data collection.

[0087] Furthermore, when processing the hologram, if there is excessive noise or distortion, it is necessary to repeatedly collect data or perform noise reduction on the data.

[0088] Furthermore, the collected data has high requirements on computing resources, and it should be ensured that the processing power of the computer can meet this demand.

[0089] This embodiment detects the pulse at the radial artery of the arm based on the detection device given in Example 1 and the measurement method given in Example 2, draws a dynamic three-dimensional view of the pulse at the radial artery of the arm by processing the data, and performs a preliminary pulse diagnosis.

[0090] The specific steps include:

[0091] S1: Collect a hologram according to the steps in Example 2, and perform the same processing on the hologram, unwrap the deformation field wrapped phase, and obtain the three-dimensional vibration of the pulse at the radial artery at a certain moment.

[0092] S2: Arrange the three-dimensional vibration conditions at each moment using the time axis to obtain a dynamic three-dimensional view of the pulse.

[0093] S3: Based on the obtained three-dimensional pulse dynamic view, observe the fluctuation of the pulse at the Cunguan point, and combine it with the pulse judgment basis in traditional Chinese medicine pulse diagnosis to preliminarily diagnose the type of pulse.

[0094] The above embodiments are merely exemplary embodiments of the present application and are not intended to limit the present invention. Any modifications, equivalent substitutions and modifications made by those skilled in the art within the essence and protection scope of the present application are still within the scope of the technical solution of the present invention.

Claims

1. A pulse detection device based on digital holography, characterized in that: The invention comprises an external upper dark box (19) and a lower dark box (20), wherein the upper dark box (19) is provided with a coherent light source laser (1), a beam splitter I (2), a beam expander I (3), a pinhole filter I (4), a Fourier lens I (5), a beam splitter II (6), an image acquisition device CCD (7), an optical path compensator (8), a total reflection mirror (9), a beam expander II (10), a Fourier lens II (11), a pinhole filter II (12), an optical power attenuator The device (16) and the partition between the upper and lower dark boxes are provided with a window (15); the lower dark box (20) is provided with a movable pulse pillow (13), and the movable pulse pillow (13) is located below the window (15); the optical path compensator (8), the optical power attenuator (16), and the image acquisition device CCD (7) are connected to the computer (18); the upper dark box (19) and the lower dark box (20) are connected, and a blackout curtain is provided at the hole (17) of the lower dark box (20); The laser light emitted by the coherent light source laser (1) is divided into two beams after passing through a beam splitter I (2). One beam passes through an optical path compensator (8), an optical power attenuator (16), a beam expander I (3), a pinhole filter I (4), and a Fourier lens I (5) to form a parallel beam, which is the reference light. The other beam passes through a reflector (9) to adjust the angle, and then passes through a beam expander II (10), a pinhole filter II (12), and a Fourier lens II (11) to form a parallel beam. This beam of light passes through a window (15) to irradiate the skin surface of the patient's arm (14). The reflected beam passes through the window (15) and returns to the upper dark box (19) and falls on the beam splitter II (6). This beam of light is the object light. The reference light and the object light form interference fringes at the beam splitter II (6) and are received by the image acquisition device CCD (7); the collected information is then transmitted to the computer (18) for processing, and finally the computer (18) completes the hologram reconstruction and analysis process and displays the detection results.

2. The pulse detection device based on digital holography according to claim 1, characterized in that: The coherent light source laser (1) adopts a helium-neon laser, and its operating wavelength is 632.8 nm.

3. The pulse detection device based on digital holography according to claim 1, characterized in that: The dark box has only a coherent light source laser (1) as the only light source, and there is no other stray light influence in the dark box.

4. The pulse detection device based on digital holography according to claim 1, characterized in that: When the device detects the pulse at the radial artery of a patient, the detection device and the patient are not in contact, and only the movable pulse pillow (13) is in contact with the patient.

5. The pulse detection device based on digital holography according to claim 1, characterized in that: The working bands of the beam splitter I (2), beam expander I (3), Fourier lens I (5), beam splitter II (6), image acquisition device CCD (7), optical path compensator (8), total reflection mirror (9), beam expander II (10), Fourier lens II (11), window (15) and optical power attenuator (16) in the device all correspond to the 632.8nm laser band.

6. A pulse detection method based on digital holography, characterized in that: The specific steps include: S1: Place and fix the arm on the movable pulse pillow and turn on the light source laser; S2: Adjust the optical power attenuator and optical path compensator, and adjust the position of the movable pulse pillow to make the light intensity and optical path of the reference light and the object light consistent; S3: Use the image collector CCD to collect the hologram and transfer the hologram to the computer for storage; S4: The first hologram acquired by the image acquisition device CCD is called the initial deformation field hologram, and the initial deformation field hologram is digitally reproduced in the computer through a reproduction program to obtain an initial deformation complex light field; S5: The hologram subsequently acquired by the image acquisition device CCD is called a changed deformation field hologram, and the changed deformation field hologram is digitally reproduced in a computer through a reproduction program to obtain a changed deformation complex light field; S6: numerically dividing the corresponding points of the initial deformed complex light field and the deformed complex light field after the change, and taking the phase angle of the complex light field after the division to obtain the wrapped phase of the deformed field after the change; S7: unwrapping the changed deformation field wrapped phase to obtain the deformation of the skin surface caused by the pulse beating at the radial artery; S8: Record the deformation of the pulse by computer software, and find the difference between the highest point and the lowest point of the vibration amplitude, that is, the vibration amplitude of the pulse; S9: Draw a waveform diagram of the pulse vibration amplitude change period through computer software, and calculate the pulse vibration frequency; S10: associating the three-dimensional pulse images at each moment to obtain a dynamic three-dimensional appearance of the pulse vibration; S11: Monitor and judge the pulse deformation through computer software and output a diagnosis report, including: pulse vibration frequency, vibration amplitude, waveform, dynamic three-dimensional morphology.

Images