Preparation method and application of summer medicated diet capable of clearing heat, promoting diuresis, tonifying spleen and nourishing stomach
Through the combination of medicinal and food in the beginning of summer medicinal diet, the shortcomings of existing medicinal products in clearing heat and dampness, calming the mind and promoting salivation, strengthening the spleen and nourishing the stomach in summer, achieving the healthy dietary needs of traditional Chinese medicine theory, providing clearing heat and dampness, calming the mind and promoting salivation, promoting salivation, and promoting salivation. , the effect of nourishing the spleen and stomach, and has good market prospects and safety.
Patent Information
- Application Number
- CN202411218888.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-02
- Publication Date
- 2024-12-13
AI Technical Summary
Existing medicinal products are difficult to follow the traditional Chinese medicine health theory, especially in summer, they cannot effectively clear heat and dampness, calm the mind and promote salivation, strengthen the spleen and nourish the stomach, and cannot meet seasonal health needs.
A method of preparing a medicinal diet for the Beginning of Summer is adopted, and the raw materials that are of the same origin as medicinal and food are combined, including coix seed, red beans, yam, poria, water chestnut, kapok, tangerine peel, pig keel and lean pork meat, etc., are pretreated, soup, seasoned and Prepare through sterilization and other steps to form medicinal foods that have the effects of clearing heat and dampness, calming the mind and promoting fluid, strengthening the spleen and nourishing the stomach.
It has achieved medicinal products that conform to the solar term under the guidance of traditional Chinese medicine theory, with good health value and market prospects. The products are delicious and easy to absorb, suitable for the needs of different groups of people, without additive preservatives, suitable for industrial production, extending the shelf life, and the raw materials are Both medicine and food are safe and have no toxic side effects.
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Figure CN119111773A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of functional foods, and in particular to a preparation method and application of a medicinal diet for the beginning of summer capable of clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach. Background Art
[0002] With the rapid development of social economy, the continuous improvement of people's living standards and health awareness, the medical model of modern society has changed from traditional treatment to preventive health care, and people are paying more and more attention to medicinal food products made of Chinese medicinal materials that are both medicinal and edible. Human life activities are closely related to the 24 solar terms. The 24 solar terms of the lunar calendar specifically reflect the changes in natural climate, and people's physiological and psychological functions also change. According to the four properties and five flavors of food and their relationship with the solar terms and human internal organs, dietary health care should focus on nourishing the liver in spring, nourishing the heart in summer, nourishing the lungs in autumn, and nourishing the kidneys in winter. The regular changes of spring temperature, summer growth, autumn harvest, and winter storage of all organisms in nature are used to regulate the human body to improve sub-healthy people and patients, thereby achieving the purpose of "preventing disease and maintaining health".
[0003] According to the theory of "harmony between heaven and man" in traditional Chinese medicine, summer is the season when the body's yang energy is at its peak in a year. The sun shines down, the ground heats up, the climate is hot, the rain is abundant, and the creatures in nature grow vigorously. The human body's yang energy is radiating outward, while the yin energy is hidden inside. The qi and blood are running vigorously and are active on the surface of the body, forming a physiological state in which the human body's yang energy is strong outside and weak inside. Since the summer heat consumes qi and hurts yin, the ability to resist diseases will naturally decrease. According to the principle of "replenishing deficiency" in traditional Chinese medicine, only "replenishing method" can better adjust the body's physiological functions and ensure good health.
[0004] In summer, it is advisable to choose supplements that are neutral and cool in nature, and have the effects of relieving heat and increasing fluid, strengthening the spleen and removing dampness, clearing the heart and promoting urination, invigorating Qi and nourishing yin, and promoting body fluid and quenching thirst.
[0005] At present, many medicinal diet formula products on the market cannot follow the basic theory of TCM health preservation very well. However, this project has developed a summer medicinal diet that follows the TCM health preservation theory, conforms to the solar terms, is easy to use, and uses both medicine and food as raw materials. It has the effects of clearing away heat and dampness, calming the nerves and promoting fluid production, and strengthening the spleen and stomach, which can fill the gap in such products. Based on the theory of TCM, it integrates the production technology of Chinese cuisine to achieve the effects of health care and deliciousness, and has good health value and broad market prospects. Summary of the invention
[0006] In order to overcome the above-mentioned shortcomings of the prior art, the purpose of the present invention is to provide a preparation method and application of a Lixia medicinal diet with the effects of clearing heat and dampness, calming the nerves and promoting fluid production, and strengthening the spleen and nourishing the stomach.
[0007] The technical solution adopted by the present invention to solve the technical problem is: a method for preparing a medicinal diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach, comprising the following steps:
[0008] A. Weigh the corresponding important parts of each material in the formula and pre-treat each raw material;
[0009] The raw materials include medicinal materials and meat materials; the meat materials are fed with cold water;
[0010] B. Put the soup ingredients into the pot and add water;
[0011] C. Control of heat and cooking time;
[0012] D. Seasoning;
[0013] E. Packaging and sterilization.
[0014] As a further improvement of the present invention: Step A pretreatment includes the following steps:
[0015] a. Medicinal materials: Clean them thoroughly before cooking and wash to remove impurities before putting them into the pot.
[0016] b. Meat ingredients: first blanch the meat in boiling water for 5 minutes.
[0017] As a further improvement of the present invention: Step B comprises the following steps:
[0018] First add 4000ml of water into the pot, then put the processed soup into the pot. After adding the soup, stir it lightly with a spoon.
[0019] As a further improvement of the present invention: Step C comprises the following steps:
[0020] After the soup ingredients are put into the pot, they should be boiled over high heat for 20 to 30 minutes, then turned to low heat and simmered, and then turned to low heat and continued to simmer for 2 hours.
[0021] As a further improvement of the present invention: Step D comprises the following steps:
[0022] When the soup is about to be removed from the heat, add 1 teaspoon of salt, about 8g, or add as needed.
[0023] As a further improvement of the present invention: Step E includes the following steps: prepare high-temperature resistant easy-to-pull aluminum bowls, put 1 portion of optimized solid medicinal materials and 10 portions of meat in each bowl in advance, and then put in about 230 ml of the soup that has been seasoned in step D, after pressing the cover, place it in a sterilizer for high-temperature sterilization at 121°C for 30 minutes.
[0024] As a further improvement of the present invention: comprising the following raw materials in parts by weight:
[0025] 20-60 parts of yam, 20-60 parts of coix seed, 20-60 parts of red bean, 10-30 parts of Poria cocos, 10-30 parts of Euryale ferox, 10-30 parts of kapok, 2-4 parts of candied dates, 1-5 parts of tangerine peel, 250-750 parts of pig dragon bones, 150-500 parts of lean pork, 3-8 parts of ginger, and 2000-10000 parts of purified water.
[0026] As a further improvement of the present invention: the following raw materials are included in parts by weight: 40 parts of yam, 40 parts of coix seeds, 30 parts of red beans, 20 parts of Poria cocos, 20 parts of Euryale ferox, 20 parts of kapok flowers, 3 parts of candied dates, 3 parts of tangerine peel, 500 parts of pig dragon bones, 300 parts of lean pork, 5 parts of ginger, and 4000 parts of purified water.
[0027] The present invention also includes the use of a heat-clearing, damp-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet, which is prepared by using the above heat-clearing, damp-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet preparation method.
[0028] Compared with the prior art, the present invention has the following beneficial effects:
[0029] (1) The present invention is guided by the theory of traditional Chinese medicine and complies with the solar terms. It is composed of materials that are both medicinal and edible. Coix seeds, red beans and Chinese yam have the effects of tonifying the spleen and stomach, promoting diuresis and removing dampness, detoxifying and eliminating carbuncle, and are the main drugs. Poria has the effects of removing dampness and promoting diuresis, benefiting the spleen and stomach and protecting the kidney, calming the nerves and promoting fluid production; Euryale ferox has the effects of benefiting the kidney and consolidating essence, tonifying the spleen and stopping diarrhea, removing dampness and stopping leukorrhea; Kapok has the effects of clearing heat and removing dampness, and detoxifying; these three flavors are the minister drugs. Tangerine peel and ginger have the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm, warming the middle and stopping vomiting, and are compatible with the main and minister drugs to restore the function of the transportation and transformation of the middle jiao, so that the food is nourishing without stagnation and nourishing without being greasy, and are adjuvant drugs. It is matched with ingredients such as pig dragon bones and lean pork that have the effects of tonifying the liver and kidneys, nourishing yin and suppressing yang, strengthening tendons and bones, nourishing blood and moistening dryness. All of them are used together to achieve the effects of clearing heat and removing dampness, calming the nerves and promoting fluid production, and tonifying the spleen and nourishing the stomach.
[0030] (2) No preservatives are added, and modern sterilization methods are used to effectively extend the shelf life;
[0031] (3) The composition of the present invention can be prepared into various dosage forms according to the needs to meet the needs of different groups of people;
[0032] (4) The raw materials of the composition are both medicinal and edible, and have the characteristics of no toxic side effects when consumed for a long time.
[0033] (5) The method for preparing the functional food provided by the present invention has stable process, high preparation efficiency, strong operability, and is suitable for large-scale industrial production.
[0034] (6) The soup of the composition is rich in flavor, delicious, easy to absorb, and convenient to take, and is deeply loved by consumers. BRIEF DESCRIPTION OF THE DRAWINGS
[0035] In order to more clearly illustrate the technical solution, the drawings required for use in the implementation will be briefly introduced below. Obviously, the drawings described below are only some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.
[0036] Figure 1 It is a process flow chart of the preparation method of the present invention. DETAILED DESCRIPTION
[0037] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the specific embodiments of the present invention and the corresponding drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0038] It should be noted that the terms "including" and "having" and any variations thereof in the specification and claims of the present invention and the above-mentioned drawings are intended to cover non-exclusive inclusions. For example, a process, method, system, product or apparatus comprising a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or apparatus.
[0039] According to the theory of traditional Chinese medicine, human life activities are closely related to the 24 solar terms. The 24 solar terms reflect the climate changes in nature, and these changes will affect people's physiological and psychological functions. Therefore, dietary health care should focus on adjusting according to the solar terms, nourishing the liver in spring, nourishing the heart in summer, nourishing the lungs in autumn, and nourishing the kidneys in winter, so as to regulate the human body, improve sub-health status and prevent diseases. Summer is the season when the human body's yang energy is at its peak. According to the theory of "correspondence between heaven and man" in traditional Chinese medicine, the body is in a state of yang energy being strong outside and weak inside at this time. Since summer heat damages yin and consumes qi, the ability to resist disease decreases. Therefore, according to the principle of "replenishing deficiency", in summer, tonics with the effects of neutral cooling, cooling off heat and increasing fluid, strengthening the spleen and removing dampness should be selected to adjust the body's physiological functions and maintain health. Existing medicated diet products on the market often fail to follow the basic theory of traditional Chinese medicine health care well. Based on the theory of traditional Chinese medicine health care and combined with the 24 solar terms, the development of medicated diet products with the same origin of medicine and food as raw materials can fill this gap. Such products not only conform to the theory of traditional Chinese medicine, but also incorporate the production process of Chinese cuisine, and have good health value and market prospects.
[0040] The present invention provides a preparation method and application of a heat-clearing, damp-removing, spleen-nourishing and stomach-nourishing Lixia medicated diet. The present invention is further described in conjunction with the accompanying drawings and embodiments: a heat-clearing, damp-removing, spleen-nourishing and stomach-nourishing Lixia medicated diet preparation method comprises the following steps:
[0041] A. Weigh the corresponding important parts of each material in the formula and pre-treat each raw material;
[0042] The raw materials include medicinal materials and meat materials; the meat materials are fed with cold water;
[0043] B. Put the soup ingredients into the pot and add water;
[0044] C. Control of heat and cooking time;
[0045] D. Seasoning;
[0046] E. Packaging and sterilization.
[0047] The invention provides a medicine for the treatment of edible phlegm, which is provided under the guidance of traditional Chinese medicine theory, conforms to the solar terms, selects medicine and food homologous materials, and realizes the effects of clearing away heat and dampness, calming the nerves and promoting the production of body fluid, and nourishing the spleen and stomach through reasonable compatibility. The combination of the monarch medicine, the ministerial medicine, and the adjuvant medicine in the formula ensures the comprehensiveness and complementarity of the effects, and the use of ingredients such as pig keel and lean pork improves the nourishing effect. The invented product does not add preservatives, adopts modern sterilization methods to extend the shelf life, and can be prepared into a variety of dosage forms according to needs to meet the needs of different groups of people. The raw materials selected by the composition are both medicine and food, with high safety, no toxic side effects, and harmless to long-term consumption. The preparation method has stable process, high preparation efficiency, and is suitable for industrial production. In addition, the product is delicious, easy to absorb, and easy to use, and is deeply loved by consumers.
[0048] As an embodiment of the present invention, a method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicinal diet comprises the following steps:
[0049] A. Weigh the corresponding important parts of each material in the formula of the optimization group, optimize the pretreatment of each raw material,
[0050] a. Medicinal materials: Clean them thoroughly before cooking and wash to remove impurities before putting them into the pot.
[0051] b. Meat ingredients: The meat (note: add cold water) should be blanched in boiling water for 5 minutes. This process is called "draining water" or "blanching water". It can not only remove the blood in the meat, but also remove some fat to avoid the soup being too greasy.
[0052] B. Check the amount of soup ingredients and water added
[0053] First, pour clean water (4000ml) into the pot, and then add the processed soup ingredients into the pot. Generally, the ingredients should be added when the water is cold, because boiling hot water will cause the protein of the ingredients to coagulate, thus weakening the flavor of the soup. Avoid the soup ingredients from sticking to the bottom of the pot. After adding the soup ingredients, stir lightly with a spoon.
[0054] C. Control of heat and time of cooking soup
[0055] After the soup is put into the pot, it should be boiled over high heat for 20 to 30 minutes, then slowly simmered over low heat. Continue to simmer over low heat for 2 hours, and the fire (600W) should not be too low to keep the soup slightly boiling.
[0056] D. Seasoning method
[0057] In order to maintain the natural flavor of the ingredients, it is recommended not to add salt first. It is best to add 1 teaspoon of salt (about 8g or as needed) when the soup is about to be removed from the heat to avoid coagulation of meat protein and affect the taste.
[0058] E. Packaging and Sterilization
[0059] Prepare high temperature resistant easy-pull aluminum bowls, put 1 portion of optimized solid medicinal materials and 10 portions of meat in each bowl in advance, and then put in about 230ml of the soup that has been seasoned in step D, cover it, and place it in the sterilizer for high temperature sterilization at 121℃ for 30 minutes. This product uses the packaging and sterilization process that combines the DTFG-I semi-automatic vacuum nitrogen filling canning machine with the DN700-1000 spray / steam dual-purpose autoclave, and uses the reverse pressure sterilization method to effectively ensure the safety of the medicinal food and a shelf life of 1 year.
[0060] In the above-mentioned medicinal diet preparation method, the packaging is any one of a high-temperature resistant easy-pull aluminum bowl and a high-temperature resistant sterilization bag.
[0061] Dosage and Administration: Oral administration, once a day, 1 bowl or 1 bag at a time.
[0062] Further: The raw materials selected in the preparation method of the Lixia Medicinal Diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach of the present invention have the following characteristics:
[0063] Chinese Yam: sweet, neutral in nature. It enters the spleen, lung and kidney meridians. It has the effects of nourishing the spleen and stomach, promoting fluid and benefiting the lungs, nourishing the kidneys and astringing semen. It is used for spleen deficiency, poor appetite, chronic diarrhea, lung deficiency, wheezing and coughing, kidney deficiency, spermatorrhea, leucorrhea, frequent urination, and thirst due to deficiency heat. Chinese Yam stir-fried with bran nourishes the spleen and strengthens the stomach. It is used for spleen deficiency, poor appetite, diarrhea, loose stools, and excessive leucorrhea. The main chemical components include proteins and amino acids, trace elements, mucins, allantoins, Chinese yam saponins, polysaccharides, etc. Modern pharmacological effects include lowering blood sugar, lowering blood lipids, protecting the liver, anti-oxidation, anti-aging, anti-tumor, enhancing immunity, and regulating intestinal microecology.
[0064] Coix seeds: sweet, light, cool in nature. Enters the spleen, stomach, and lung meridians. Has the effects of promoting water and eliminating dampness, strengthening the spleen and stopping diarrhea, removing numbness, draining pus, and detoxifying and dispersing knots. Used for edema, beriberi, dysuria, spleen deficiency diarrhea, dampness and stiffness, lung abscess, intestinal abscess, warts, and cancer. The main chemical components include fatty oil, coix ester, coixol, coixolide, as well as coix polysaccharides A, B, C, amino acids, vitamin B1, etc. Modern pharmacological effects include anti-tumor, analgesia and anti-inflammatory, sedation, regulation of sugar and lipid metabolism, enhancement of immunity, lowering blood pressure, anti-oxidation, anti-aging, whitening, etc.
[0065] Adzuki bean: sweet, sour, neutral in nature. It enters the heart and small intestine meridians. It has the effects of promoting diuresis and reducing swelling, detoxifying, eliminating carbuncle and draining pus, nourishing blood and nourishing the skin, moistening the intestines and relieving constipation. It is used for edema, beriberi, jaundice, red urine, rheumatism, carbuncle, intestinal carbuncle and abdominal pain. The main chemical components include triterpenes, glycosides, tannins and flavonoids. Modern pharmacological effects include promoting diuresis and reducing swelling, clearing away heat and detoxifying, etc.
[0066] Poria: sweet, light, and neutral in nature. It enters the heart, spleen, lung, and kidney meridians. It has the effects of dispelling dampness and promoting diuresis, benefiting the spleen and stomach and protecting the kidneys, and calming the nerves and promoting the production of body fluids. It is used to treat nephritis, colitis, urinary tract infections, hepatitis, etc. The main chemical components include triterpenes, polysaccharides, sterols, volatile oils, etc. Modern pharmacological effects include dispelling dampness and promoting diuresis, protecting the liver, anti-tumor, anti-oxidation, anti-aging, and immune regulation.
[0067] Gorgon Fruit: Sweet, astringent, neutral in nature. Enters the spleen and kidney meridians. Has the effects of nourishing the kidney and consolidating essence, tonifying the spleen and stopping diarrhea, removing dampness and stopping leukorrhea. Used to treat spermatorrhea, enuresis, frequent urination, spleen deficiency and chronic diarrhea, leukorrhea, leukorrhea, kidney disease, chronic enteritis, sequelae of stroke, etc. The main chemical components contain starch, protein, fat, carbohydrates, calcium, phosphorus, iron, thiamine, riboflavin, nicotinic acid, ascorbic acid, etc. Modern pharmacological effects include lowering blood sugar, anti-oxidation, anti-fatigue, anti-neuronal cell toxicity, anti-myocardial ischemia, etc.
[0068] Kapok flower: light, astringent, flat. It belongs to the large intestine meridian. It has the effects of clearing away heat, removing dampness and detoxifying. It is used for diarrhea, dysentery, metrorrhagia, sores. The main chemical components include volatile oils, flavonoids, phenylpropanoids, steroids, fatty acids, trace elements, triterpenoid compounds, phenolic acid compounds, etc. Modern pharmacological effects include anti-inflammatory and antibacterial, anti-tumor, anti-oxidation, hypoglycemic, liver protection, etc.
[0069] Tangerine peel: bitter, pungent, warm. Enters the lung and spleen meridians. Has the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm. Used for abdominal distension, loss of appetite, vomiting and diarrhea, cough and sputum. The main chemical components include flavonoids, volatile oils, polysaccharides, alkaloids, trace elements, phenols, vitamins, limonin and inositol. Modern pharmacological effects include improving the cardiovascular system, respiratory system, digestive system, improving sugar metabolism, lipid metabolism, protecting the liver, anti-tumor, antibacterial and anti-inflammatory, antioxidant, scavenging free radicals, antiviral, immunosuppressive, etc.
[0070] Pig dragon bone: slightly warm, sweet. Enters the kidney and liver meridians. It has the effects of nourishing the liver and kidney, nourishing yin and suppressing yang, strengthening tendons and bones, etc. The main chemical components contain minerals, proteins, amino acids, iron, vitamins, etc. Modern pharmacological effects include enhancing immunity, improving anemia, relieving fatigue, and promoting bone health.
[0071] Pork lean meat: sweet, salty, neutral in nature. Enters the spleen, stomach, and kidney meridians. It has the effects of nourishing the kidney and yin, nourishing blood and moistening dryness. It is used to treat stomatitis, dermatitis, angular cheilitis, oral ulcers, vaginal itching, etc. The main chemical components contain protein, carbohydrates, fat, multiple vitamins, niacin, multiple minerals, etc. Modern pharmacological effects include providing nutrition for the human body, promoting the repair of damaged cells, improving malnutrition and physical weakness symptoms, increasing appetite, relieving indigestion, improving memory, improving vision, preventing vision loss, supplementing iron, supplementing calcium, etc.
[0072] Ginger: spicy, slightly warm. Enters the lung, spleen, and stomach meridians. It has the effects of dispelling cold, warming the middle and stopping vomiting, warming the lungs and stopping coughs, and detoxification. It is used to treat colds, spleen and stomach coldness, stomach cold vomiting, lung cold coughs, and detoxification of fish and crabs. The main chemical components include volatile oils, terpenes, resins, amino acids, flavonoids, etc. Modern pharmacological effects include antipyretic and analgesic, antiemetic, gastric mucosal protection, intestinal peristalsis promotion, liver protection and gallbladder promotion, anti-inflammatory, antibacterial, antioxidant, expectorant and cough relieving, etc.
[0073] The present invention provides a recipe for Lixia medicated diet, which comprehensively utilizes the spleen and stomach of traditional Chinese medicine as the source of the biochemical transformation of Yingwei Qi and blood. The spleen and stomach are qi-deficient, and the transport is weak, so the diet is reduced, the qi is less and the speech is lazy. If the spleen is deficient, the clear yang does not rise and sinks into the lower jiao, and the depression is not reached, and fever occurs. In the prescription, coix seed, red bean and yam are reused, which have the effects of tonifying the spleen and stomach, promoting water and dampness, detoxifying and eliminating carbuncle, and are the main medicine. Poria has the effects of penetrating dampness and promoting water, benefiting the spleen and stomach to protect the kidney, calming the mind and producing body fluid; Euryale has the effects of benefiting the kidney and consolidating essence, tonifying the spleen and stopping diarrhea, removing dampness and stopping leukorrhea; Kapok has the effects of clearing heat and promoting dampness, and detoxifying; these three flavors are the ministerial medicines. Tangerine peel and ginger have the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm, warming the middle and stopping vomiting, etc., and are compatible with the main and ministerial medicines to restore the function of transportation and transformation of the middle jiao, so that the supplement is not stagnant, and the nourishment is not greasy, and it is the adjuvant. It is paired with ingredients such as pig keel and lean pork, which have the effects of nourishing the liver and kidney, nourishing yin and suppressing yang, strengthening tendons and bones, nourishing blood and moistening dryness. All of these ingredients are used together to achieve the effects of clearing away heat and dampness, calming the mind and promoting fluid production, and nourishing the spleen and stomach.
[0074] In order to detect the taste of the Lixia medicinal diet prepared by the Lixia medicinal diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach and the accuracy of the results, the decoction process of the medicinal diet adopts a four-factor three-level orthogonal test, and the four factors are: the number of decoctions (A), the decoction time (B), the amount of water added (C), the firepower (D), and the medicinal diet sensory score is used as the evaluation index. The levels that have a greater impact on the score index are selected respectively, and L9 (3 4) design for orthogonal test. The factors and levels are shown in Table 1, and the orthogonal test and overall evaluation results are shown in Table 1
[0075] Table 1. Table of factors and levels in orthogonal experiment design of medicinal diet
[0076]
[0077] Table 2 Orthogonal test L9(3 4 ) and the overall evaluation results are shown in Table
[0078]
[0079]
[0080] The orthogonal test and its results are shown in Table 2. When the overall evaluation is used as an indicator, the amount of water added has the greatest impact, followed by firepower, decoction time, and number of decoctions. The optimal combination is A2B1C3D2 (i.e., decoction number 1, decoction time 2 hours, water addition 3L, and firepower 600).
[0081] The sensory evaluation of the prepared Lixia medicinal diet comprises the following steps:
[0082] 10 people were randomly selected to score based on the product sensory evaluation (30 points) (color, smell, taste, overall acceptability of taste) and personal physical performance (70 points) (current main discomfort and symptoms, facial features, mental state, urination, defecation, appetite, tongue coating, sleep) on a 100-point scale. The sensory evaluation standards for medicinal diets are shown in Table 3.
[0083] Table 3 Sensory evaluation standards for medicinal diet
[0084]
[0085]
[0086]
[0087] Note: The average scores of 9 orthogonal samples from 10 people are: 91, 93, 94, 93, 94, 92, 95, 89, 92
[0088] In order to detect the efficacy of the Lixia medicinal diet prepared by the Lixia medicinal diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach, a research experiment was conducted on the effect of the Lixia medicinal diet on the direct sleep of mice and the effect of extending the sleep time of mice by sodium pentobarbital.
[0089] Experimental methods: SPF male NIH mice were randomly divided into negative control group, positive control group and Lixia decoction group, 10 mice / group. All mice were intragastrically administered with the corresponding dose of the test sample at 19mL / kg, and the negative control group was given an equal amount of purified water, twice a day, for 30 consecutive days. It was observed whether the animals in each group fell asleep within 1 hour after administration of D29, and whether the intraperitoneal injection of 55mg / kg of sodium pentobarbital 1 hour after the last administration of the test sample could prolong the sleeping time of sodium pentobarbital.
[0090] Animal information: 34 SPF-grade NIH mice, male, body weight at administration ranged from 18.5 to 23.4 g.
[0091] Animal source: from Zhuhai Baishitong Biotechnology Co., Ltd., production license number: SCXK(Guangdong)2020-0051, animal certificate number: 44822700033787.
[0092] Feeding and management: The animals were kept in the SPF animal room of Zhuhai Baishitong Biotechnology Co., Ltd. Building 3. Experimental certificate number: 00395606, ethics number: IAC24W038(C). Animal feeding conditions: group-raising, 5 / cage, feeding temperature and humidity 20-26℃, 40-70%, 12h:12h day and night lighting; the feeding room conditions were always kept stable to ensure the reliability of the test results. During the experiment, the animals were fed with corresponding pellet feed according to the experimental requirements. The SPF feed was provided by Jiangsu Medison Biomedicine Co., Ltd., and the SFP animal drinking online sterilized water. The animals were free to eat and drink.
[0093] Identification method: Use ear tagging and double numbering for identification.
[0094] Euthanasia: The patients were killed by an overdose of anesthesia via intraperitoneal injection of 20% ethyl formate 1.5g / kg body weight. The bodies were temporarily stored in a body freezer and handed over to a qualified third-party organization by Zhuhai Baishitong Biotechnology Co., Ltd. for pollution-free disposal.
[0095] Quarantine observation: The purchased animals were quarantined for 3 days. During this period, the animals were checked once a day. All animals showed no abnormalities. 30 of them were included in the formal experiment, and the remaining 4 were euthanized and eliminated.
[0096] Reagent preparation: Sodium pentobarbital solution (5.5 mg / mL): Accurately weigh 137.5 mg of sodium pentobarbital powder, add 25 mL of normal saline and dissolve and mix well.
[0097] Preparation of positive control solution: Compound diazepam tablet solution (0.16 mg / mL): Take 3 tablets of compound diazepam (each tablet contains 1.25 mg of diazepam), grind into powder, add 23.4 mL of purified water to dissolve and mix well.
[0098] Grouping: After passing the quarantine, 30 NIH mice were randomly divided into a negative control group, a positive control group, and a Lixia soup diet group, 10 mice per group. The excess animals were euthanized. The groups are shown in Table 4 below.
[0099] Table 4 Grouping table
[0100]
[0101] Drug administration: All mice were intragastrically administered with the test sample at a dose of 19 mL / kg, twice a day, for 30 consecutive days. The negative control group was given an equal amount of purified water.
[0102] The animals were observed daily for general clinical signs.
[0103] Direct sleep test: After 29 consecutive days of drug administration, observe whether the animals in each group fall asleep within 1 hour after drug administration. The loss of righting reflex is used as an indicator of sleep. When the mouse is placed in a dorsal recumbent position, it can turn right immediately. If it cannot turn right for more than 30 to 60 seconds, it is considered that the righting reflex has disappeared and the mouse has entered sleep.
[0104] Test for prolonging the sleeping time of sodium pentobarbital: One hour after the animals were last given the solvent and the test samples of different concentrations, each group of animals was intraperitoneally injected with 55 mg / kg of sodium pentobarbital (at this dose, 100% of the mice fell asleep, but the sleeping time was not too long). The injection volume was 10 mL / kg, and the disappearance of the righting reflex was used as an indicator to observe whether the test sample could prolong the sleeping time of sodium pentobarbital.
[0105] All data are SPSS 21.0 software was used for statistical analysis. For measurement data with homogeneous variance, one-way analysis of variance with pairwise comparison between groups was used. For unequal variance, rank sum test was used for statistical analysis. Rank sum test was used for statistical analysis of rank data or percentages and ratios. P ≤ 0.05 was considered statistically significant.
[0106] Weight results ( n=10,g)
[0107]
[0108] Compare the difference in prolonged sleep time between the experimental group and the control group. If the prolonged sleep time is significant, the experimental result is positive.
[0109] Results of the experiment on prolonging the sleep time of mice by sodium pentobarbital ( n=10,g)
[0110]
[0111] If any two of the three tests, namely, the pentobarbital sodium sleep time extension test, the pentobarbital sodium (or barbital sodium) subthreshold dose hypnosis test, and the barbital sodium sleep latency test, are positive, and there is no obvious direct sleep effect, it can be determined that the test sample has the effect of helping to improve sleep.
[0112] Results: General clinical condition Results: During the experiment, no abnormalities were observed in the body shape, fur, skin, feces, muscle tension, gait, spirit, breathing and other general clinical observations of all mice, and their weight increased normally. There was no statistical difference in the weight of mice in each group at each time point compared with the negative control group (P>0.05).
[0113] Results of direct sleep test: One hour after each group of animals were gavaged with the corresponding test samples, all mice did not fall asleep, indicating that the test samples had no direct sleep effect on mice.
[0114] The results of the test on prolonging the sleeping time with sodium pentobarbital: compared with the negative control group, the mice in the positive control group had a significantly increased sleeping time with sodium pentobarbital (P<0.01); there was no statistical difference in the sleeping time with sodium pentobarbital (P>0.05) in the mice in the Lixia soup group.
[0115] Conclusion: Under the conditions of this experiment, according to the 2023 edition of "Health Food Function Test and Evaluation Methods-Improving Sleep Function Test Methods", Lixia Soup has no direct sleep effect, and no effect of prolonging the sleep time of sodium pentobarbital was observed, indicating that the experimental results of Lixia Soup to prolong the sleep time of sodium pentobarbital are negative.
[0116] The main function of the present invention: The present invention provides a recipe for the beginning of summer medicinal diet, which comprehensively uses the spleen and stomach of traditional Chinese medicine as the source of the biochemical transformation of the nutrient qi and blood. The spleen and stomach are qi-deficient, and the transport is weak, so the diet is reduced, the qi is less and the speech is lazy. The spleen is deficient, and the clear yang does not rise and sinks into the lower jiao, and the depression is not reached, resulting in fever. The prescription reuses coix seed, red bean and yam, which have the effects of tonifying the spleen and stomach, promoting water and dampness, detoxifying and eliminating carbuncle, and are the main medicine. Poria has the effects of penetrating dampness and promoting water, benefiting the spleen and stomach to protect the kidney, calming the mind and producing fluid; Euryale has the effects of benefiting the kidney and consolidating essence, tonifying the spleen and stopping diarrhea, removing dampness and stopping leukorrhea; Kapok has the effects of clearing heat and dampness, and detoxifying; these three flavors are the minister medicines. Tangerine peel and ginger have the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm, warming the middle and stopping vomiting, etc., and are compatible with the main and minister medicines to restore the function of the transportation and transformation of the middle jiao, so that the supplement is not stagnant, and the nourishment is not greasy, which is the adjuvant medicine. It is matched with ingredients such as pig dragon bones and lean pork, which have the effects of nourishing the liver and kidney, nourishing yin and suppressing yang, strengthening tendons and bones, nourishing blood and moistening dryness. All of them are used together to play the effects of clearing heat and dampness, calming the nerves and promoting fluid production, and nourishing the spleen and stomach; under the guidance of the theory of traditional Chinese medicine, the present invention conforms to the solar terms and is composed of medicine and food materials of the same origin. Coix seeds, red beans and yam have the effects of nourishing the spleen and stomach, promoting water and dampness, detoxifying and eliminating carbuncle, and are the main medicine. Poria has the effects of penetrating dampness and promoting water, benefiting the spleen and stomach and protecting the kidney, calming the nerves and promoting fluid production; Euryale has the effects of benefiting the kidney and consolidating essence, nourishing the spleen and stopping diarrhea, removing dampness and stopping leukorrhea; Kapok has the effects of clearing heat and dampness, and detoxifying; these three flavors are therefore the minister medicines. Tangerine peel and ginger have the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm, warming the middle and stopping vomiting, etc., and are compatible with the monarch and minister medicines to restore the function of the transportation and transformation of the middle jiao, so that it can be nourished without stagnation, nourishing without greasiness, and is an adjuvant. It is paired with ingredients such as pig keel and lean pork, which have the effects of nourishing liver and kidney, nourishing yin and suppressing yang, strengthening tendons and bones, nourishing blood and moistening dryness. All of them are used together to achieve the effects of clearing away heat and dampness, calming the mind and promoting fluid production, and nourishing the spleen and stomach; the combination has a rich soup flavor, delicious taste, easy absorption, and convenient consumption, and is deeply loved by consumers.
[0117] In summary, after reading the present invention document, ordinary technicians in this field can make various other corresponding transformation schemes based on the technical scheme and technical concept of the present invention without creative mental work, which all fall within the scope of protection of the present invention.
Claims
1. A method for preparing a medicinal diet for the beginning of summer that clears away heat, removes dampness, strengthens the spleen and nourishes the stomach, characterized in that: The following steps are involved: A. Weigh the corresponding important parts of each material in the formula and pre-treat each raw material; The raw materials include medicinal materials and meat materials; the meat materials are fed with cold water; B. Put the soup ingredients into the pot and add water; C. Control of heat and cooking time; D. Seasoning; E. Packaging and sterilization.
2. The method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet according to claim 1, characterized in that: Step A pretreatment includes the following steps: a. Medicinal materials: Clean them thoroughly before cooking and remove impurities before putting them into the pot. b. Meat ingredients: first blanch the meat in boiling water for 5 minutes.
3. The method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet according to claim 1, characterized in that: Step B includes the following steps: First add 4000ml of water into the pot, then put the processed soup into the pot. After adding the soup, stir it lightly with a spoon.
4. The method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet according to claim 1, characterized in that: Step C includes the following steps: After the soup ingredients are put into the pot, they should be boiled over high heat for 20 to 30 minutes, then turned to low heat and simmered, and then turned to low heat and continued to simmer for 2 hours.
5. The method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet according to claim 1, characterized in that: Step E includes the following steps: Prepare high-temperature resistant easy-pull aluminum bowls, put 1 portion of optimized solid medicinal materials and 10 portions of meat in each bowl in advance, then add about 230 ml of the seasoned soup from step D, cover it, and place it in a sterilizer at 121°C for 30 minutes.
6. The method for preparing the Lixia Medicinal Diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 20-60 parts of yam, 20-60 parts of coix seed, 20-60 parts of red bean, 10-30 parts of Poria cocos, 10-30 parts of Euryale ferox, 10-30 parts of kapok, 2-4 parts of candied dates, 1-5 parts of tangerine peel, 250-750 parts of pig dragon bones, 150-500 parts of lean pork, 3-8 parts of ginger, and 2000-10000 parts of purified water.
7. The method for preparing a heat-clearing, dampness-removing, spleen-strengthening and stomach-nourishing Lixia medicated diet according to claim 6, characterized in that: The invention comprises the following raw materials in parts by weight: 40 parts of yam, 40 parts of coix seeds, 30 parts of red beans, 20 parts of tuckahoe, 20 parts of euryale seeds, 20 parts of kapok flowers, 3 parts of candied dates, 3 parts of tangerine peel, 500 parts of pig dragon bones, 300 parts of lean pork, 5 parts of ginger, and 4000 parts of purified water.
8. Use of a Lixia medicinal diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach, prepared by the method for preparing a Lixia medicinal diet for clearing away heat, removing dampness, strengthening the spleen and nourishing the stomach according to any one of claims 1 to 7.
