Pellet type buccal cigarette and preparation method thereof

Abstract

The invention discloses a pellet type buccal cigarette and a preparation method thereof. The preparation method comprises the following steps: S1, preparing the spraying liquid from the adhesive, the nicotine salt, the pH regulator, the sweetening agent, the cooling agent and the essence. And S2, based on combination of centrifugal granulation and fluidization, performing coating treatment on the medicinal pill core by using a spraying liquid to obtain a wet pill. S3, the wet pellets are subjected to sieving treatment, and pellet particles with the particle size ranging from 300 micrometers to 1500 micrometers are obtained. And S4, drying the pellet particles, and bagging to obtain the buccal cigarette product. The prepared buccal cigarette product is high in quality, the discomfortableness caused by too high nicotine release speed is overcome, the problems that fragrance is poor in release uniformity, short in release time and prone to deterioration are solved, and the buccal cigarette has the advantages of being comfortable in taste, small in irritation to the mouth, good in fragrance uniformity and good in sensory experience and has excellent popularization prospects.

Description

Technical Field

[0001] The invention relates to the field of nicotine buccal products, in particular to a micro-pellet type buccal cigarette, and also to a preparation method of the buccal cigarette. Background Art

[0002] Oral nicotine products are becoming more and more popular among consumers due to their exquisite appearance and unique taste experience. At present, in the preparation process of nicotine oral products, nicotine, flavors, fillers and flavoring agents are usually directly mixed into powder. The oral tobacco products made by this method will cause the nicotine release rate to be too fast, which is easy to cause discomfort, and the flavor release uniformity is poor, the release time is short, and it is easy to deteriorate, thus affecting the quality of the product.

[0003] At present, various methods have been used to solve the problem of nicotine release being too fast. For example, CN114521669A discloses a nicotine-stabilized oral tobacco product and a preparation method thereof, which mixes nicotine and a polymer material into a solution, and coats the oral tobacco particles to allow nicotine to be slowly released during the oral process. Another example is CN115997965A discloses a nicotine sustained-release oral tobacco and a preparation method thereof, which achieves a sustained-release effect with the help of a composite solid nicotine salt. However, there is currently no clear solution on how to overcome the excessively fast nicotine release rate and at the same time improve the uniformity of flavor release. Summary of the invention

[0004] In view of the above-mentioned shortcomings of the prior art, the object of the present invention is to provide a micro-pellet type buccal cigarette and a preparation method thereof to solve the problem of too fast nicotine release rate and improve the uniformity of the flavor release of the buccal cigarette.

[0005] A method for preparing a pellet-type buccal cigarette comprises the following steps: S1 takes a binder, nicotine salt, a pH adjuster, a sweetener, a cooling agent and a flavor to prepare a spray liquid; S2 is based on the combination of centrifugal granulation and fluidization, and uses a spray liquid to coat the medicinal pellet core to obtain wet pellets; The coating treatment method is specifically performed as follows: S21 takes the medicinal pellet core as the masterbatch and adds it into the coating machine; The S22 medicinal pill core is driven by the coating machine turntable to perform centrifugal motion. At this time, the spray liquid, filler and preservative are sprayed into the coating machine through the peristaltic pump, so that the pill core grows; S23 spraying is finished, lubricant is added to obtain wet pellets; S3: sieving the wet pellets to obtain pellets with a particle size of 300-1500 μm; S4: drying the micro-pellets and bagging them to obtain a snus product.

[0006] As a further improvement of the above scheme, the method for preparing the spray liquid is specifically performed as follows: S11: dissolving a binder in pure water to obtain a binder solution; S12: Add nicotine salt, pH adjuster, sweetener, cooling agent and flavor to the adhesive solution in sequence, and stir at room temperature for 10 to 20 minutes until the mixture is completely mixed.

[0007] As a further improvement of the above scheme, the binder is at least one of povidone, sodium carboxymethyl cellulose, sodium carboxymethyl starch, hydroxypropyl methylcellulose, methyl cellulose, ethyl cellulose and microcrystalline cellulose. The nicotine salt is at least one of pure nicotine, nicotine tartrate, nicotine tartrate dihydrate, nicotine levulinate, nicotine lactate, nicotine salicylate, nicotine benzoate, nicotine malate and nicotine citrate.

[0008] As a further improvement of the above scheme, the pH adjuster is at least one of sodium hydroxide, potassium hydroxide, sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, sodium phosphate, disodium hydrogen phosphate, sodium acetate, potassium acetate, sodium pyrophosphate, potassium phosphate, dipotassium hydrogen phosphate, calcium hydrogen phosphate, potassium polymetaphosphate, sodium citrate, potassium citrate, sodium gluconate and diammonium hydrogen phosphate.

[0009] As a further improvement of the above scheme, the sweetener is at least one of monosaccharide, disaccharide, trisaccharide, polysaccharide, polyol, acesulfame potassium, aspartame, sucralose and neotame. The cooling agent is any one of WS-3, WS-5, WS-10, WS-12, WS-23, WS-27 and menthol. The flavor is any one of strawberry, watermelon, mango, grape, banana, lemon, orange, blueberry, raspberry, mint and coffee flavor.

[0010] As a further improvement of the above solution, the particle size of the medicinal pill core is 100-800 μm, and the medicinal pill core is at least one of a microcrystalline cellulose pill core and a sucrose pill core.

[0011] As a further improvement of the above scheme, in S22, the rotating disk speed is 200-400r / min, the fan speed is 1000~3000r / min, the air inlet temperature is 40~80°C, the atomization pressure is 0.1~0.5MPa, and the peristaltic pump speed is 2~30r / min. The filler is at least one of mannitol, lactose, isomaltulose, sorbitol, maltodextrin, microcrystalline cellulose and pregelatinized starch. The preservative is at least one of potassium sorbate, sodium benzoate and ethyl paraben; the lubricant is at least one of magnesium stearate, talc and silicon dioxide.

[0012] As a further improvement of the above scheme, the sieving method is specifically operated as follows: the wet pellets are sifted using a layer screen to screen out pellet particles with a particle size of 300-1500 μm. A 16-mesh to 50-mesh screen is used as the layer screen.

[0013] As a further improvement of the above scheme, the drying method is specifically operated as follows: the screened micro-pellet particles are placed in a coating machine and dried for 5 to 20 minutes, the inlet air temperature is 40 to 80°C, and the fan speed is 1000 to 3000 r / min.

[0014] A buccal tobacco product is prepared by the method for preparing a micro-pellet type buccal tobacco, and the buccal tobacco product has the following composition by weight: 15% to 50% of a medicinal pellet core, 1% to 30% of a nicotine salt, 1% to 30% of a binder, 10% to 70% of a filler, 0.1% to 1% of a lubricant, 1% to 15% of a sweetener, 1% to 10% of a flavor, 0.5% to 3% of a pH adjuster, 0.01% to 1% of a cooling agent, 0.05% to 1% of a preservative, and 5% to 10% of pure water.

[0015] Compared with the prior art, the present invention has the following beneficial effects: The present invention provides a specific solution to the problem of overcoming the problem of too fast nicotine release rate and improving the uniformity of flavor release at the same time, that is, using pellet cores for coating to prepare oral tobacco products in the form of micro-pellets. Compared with traditional unit preparations, micro-pellets have many advantages such as good fluidity, uniform quality, stable release, and high bioavailability. In addition, different release properties can be obtained by selecting suitable skeleton materials and coating materials, meeting the requirements of the multi-particle drug release system for release at different times and locations. At the same time, the defects of a single micro-pellet do not affect the release behavior of the overall preparation.

[0016] The oral tobacco product prepared by the present invention has high quality, overcomes the problems of discomfort caused by too fast nicotine release speed, poor flavor release uniformity, short release time, and easy deterioration, has the advantages of comfortable taste, small entrance irritation, good flavor uniformity, and good sensory experience, and has excellent promotion prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 The nicotine release curves of the snus prepared in Example 1, Example 2, Comparative Example 1 and Comparative Example 2 of the present invention are shown.

[0018] Figure 2 Shown are the olfactory analysis results of Example 1 and Comparative Example 1.

[0019] Figure 3 Shown are the olfactory analysis results of Example 2 and Comparative Example 2.

[0020] Figure 4 The following table shows the sensory quality evaluation criteria for the oral preparations prepared in Examples 1 and 2 and Comparative Examples 1 and 2.

[0021] Figure 5 The following are the evaluation results of the sensory quality of the oral preparations of each group of Examples 1 and 2 and Comparative Examples 1 and 2. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is further described in detail below in conjunction with the embodiments. Additional aspects and advantages of the present invention will be given in part in the following description, and will become apparent from the following description, or will be understood through the practice of the present invention. It should be understood that the following description is only used to explain the present invention and is not intended to limit the present invention.

[0023] As used herein, the terms "comprises," "including," "contains," or any other variation thereof, are intended to cover a non-exclusive inclusion. For example, a composition, process, method, article, or apparatus that comprises the listed elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, process, method, article, or apparatus.

[0024] When an amount, concentration, or other value or parameter is expressed as a range, a preferred range, or a range limited by a series of upper preferred values ​​and lower preferred values, this should be understood as specifically disclosing all ranges formed by any pairing of any range upper limit or preferred value with any range lower limit or preferred value, regardless of whether the range is disclosed separately. For example, when a range of "1 to 5" is disclosed, the described range should be interpreted as including a range of "1 to 4", "1 to 3", "1 to 2", "1 to 2 and 4 to 5", "1 to 3 and 5" etc. When a numerical range is described in this article, unless otherwise specified, the range is intended to include its end values ​​and all integers and fractions within the range.

[0025] The specific embodiments of the present invention are described in detail below. Example 1

[0026] This embodiment provides a method for preparing a pellet-type oral cigarette, which comprises the following steps: S1: dissolve povidone in pure water to obtain a solution, then add pure nicotine, sodium carbonate, sucralose, WS-23 and blueberry flavor to the solution in sequence, stir at room temperature for 10 minutes until completely mixed, and obtain a spray liquid.

[0027] S2 takes sucrose pellet cores with a particle size of 600μm and adds them into the coating machine. The sucrose pellet cores are driven by a turntable with a rotation speed of 200r / min to perform centrifugal motion. At this time, the spray liquid, filler (mannitol + maltodextrin + pregelatinized starch + sorbitol + microcrystalline cellulose) and ethyl paraben are sprayed into the coating machine through a peristaltic pump with a rotation speed of 10r / min to make the pellet core grow. In the above process, the fan speed is 2000r / min, the inlet air temperature is 50℃, and the atomization pressure is 0.2MPa. After the spraying is completed, silicon dioxide is added to obtain wet pellets.

[0028] S3 uses a 20-mesh screen to sieve the wet pellets to screen out pellet particles with a particle size of 800 μm.

[0029] S4 puts the screened micro-pellets into the coating machine, adjusts the air inlet temperature to 50°C, the fan speed to 2000r / min, and dries for 10 minutes. The micro-pellets are then bagged at 0.5g / bag to obtain oral tobacco products.

[0030] The oral tobacco product prepared by the preparation method of this embodiment has the following composition by weight: sucrose pellet core 15%, povidone 2%, pure nicotine 1.4%, sodium carbonate 2%, mannitol 30%, maltodextrin 10%, pregelatinized starch 6%, sorbitol 15%, microcrystalline cellulose 7%, sucralose 0.04%, blueberry flavor 5%, ws-23 0.07%, ethyl paraben 0.15%, silicon dioxide 0.2%, and water 6.14%. Example 2

[0031] This embodiment provides a method for preparing a pellet-type oral cigarette, which comprises the following steps: S1: Dissolve hydroxypropyl methylcellulose in pure water to obtain a solution, then add nicotine benzoate, sodium carbonate, sucralose, WS-23 and strawberry flavor to the solution in sequence, stir for 15 minutes at room temperature until completely mixed to obtain a spray liquid.

[0032] S2 takes sucrose pellet cores with a particle size of 800μm and adds them into the coating machine. The sucrose pellet cores are driven by a turntable with a rotation speed of 300r / min to perform centrifugal motion. At this time, the spray liquid, filler (mannitol + maltodextrin + pregelatinized starch + sorbitol + lactose) and sodium benzoate are sprayed into the coating machine through a peristaltic pump with a rotation speed of 20r / min to make the pellet core grow. In the above process, the fan speed is 2500r / min, the inlet air temperature is 50℃, and the atomization pressure is 0.2MPa. After the spraying is completed, magnesium stearate is added to obtain wet pellets.

[0033] S3 uses a 14-mesh screen to sieve the wet pellets to screen out pellet particles with a particle size of 1200 μm.

[0034] S4 puts the screened micro-pellets into the coating machine, adjusts the inlet air temperature to 50°C, the fan speed to 2500r / min, and dries for 15 minutes. The micro-pellets are then bagged at 0.5g / bag to obtain oral tobacco products.

[0035] The oral tobacco product prepared by the preparation method of this embodiment has the following composition by weight: 45% sucrose pellet core, 3% hydroxypropyl methylcellulose, 1% nicotine benzoate, 0.75% sodium carbonate, 10% lactose, 6% maltodextrin, 11% pregelatinized starch, 4% sorbitol, 5% mannitol, 0.02% sucralose, 5% strawberry flavor, 0.07% ws-23, 0.2% sodium benzoate, 0.5% magnesium stearate, and 8.46% water.

[0036] In order to facilitate the performance analysis of the oral tobacco products prepared in Examples 1 and 2, Comparative Examples 1 and 2 are designed below. The preparation methods adopted in Comparative Examples 1 and 2 do not introduce medicinal pellet cores.

[0037] Comparative Example 1 This comparative example provides a method for preparing a buccal tobacco product, which comprises the following steps: Step 1: Take pregelatinized starch, mannitol, sorbitol and microcrystalline cellulose, mix them evenly to obtain a mixed powder.

[0038] Step 2: Add pure nicotine, sodium carbonate and WS-23 to the mixed powder in sequence and mix well; Step 3. Continue to add sucralose, neotame, sodium chloride and blueberry flavor and stir evenly; Step 4: Finally, add water to adjust the humidity of the product, stir evenly, and bag it at 0.5 g / bag to obtain a snus product.

[0039] The oral tobacco product prepared in this comparative example has the following composition by weight: 15% pregelatinized starch, 6% mannitol, 8% sorbitol, 38% microcrystalline cellulose, 1.4% pure nicotine, 1% sodium carbonate, 0.1% WS-23, 0.3% sucralose, 0.02% neotame, 8% blueberry flavor, 1% sodium chloride, and 21.18% water.

[0040] Comparative Example 2 This comparative example provides a method for preparing a buccal tobacco product, which comprises the following steps: Step 1: Take maltodextrin, lactose, sorbitol and microcrystalline cellulose, mix them evenly to obtain a mixed powder.

[0041] Step 2: Add nicotine benzoate, sodium carbonate and WS-23 to the mixed powder in sequence and mix well; Step 3. Continue to add sucralose, neotame, sodium chloride and strawberry flavor and stir evenly; Step 4: Finally, add water to adjust the humidity of the product, stir evenly, and bag it at 0.5 g / bag to obtain a snus product.

[0042] The oral tobacco product prepared in this comparative example has the following composition by weight: 20% maltodextrin, 10% lactose, 5% sorbitol, 32% microcrystalline cellulose, 1% nicotine benzoate, 0.75% sodium carbonate, 0.1% WS-23, 0.3% sucralose, 0.02% neotame, 8% strawberry flavor, 1% sodium chloride, and 21.83% water.

[0043] The following are the nicotine release evaluation test, aroma active component GC-O analysis, olfactory analysis and taste evaluation test of the snus prepared in Examples 1-2 and Comparative Examples 1-2.

[0044] Nicotine release evaluation test: The oral cigarettes prepared in Examples 1-2 and Comparative Examples 1-2 were placed in 50 mL of phosphate buffer with a pH value of 8.1, and samples were taken for testing according to the experimental design time. Based on the relationship between nicotine sustained release and time, the release curve of nicotine / nicotine salt was prepared, as shown in FIG. Figure 1 As shown. Figure 1 It can be seen that the release rates of Comparative Examples 1 and 2 both reach more than 90% at about 5 minutes, while the release rates of Examples 1 and 2 reach more than 90% at about 9 minutes. The above results prove that the nicotine release rate of the buccal cigarette prepared by the preparation method of the present invention is slower, and nicotine can be continuously and slowly released in the oral cavity, thus solving the problem of too fast nicotine release in the traditional preparation method.

[0045] GC-O analysis of aroma active ingredients: When conducting the nicotine release evaluation test, the aroma olfactory evaluation was performed on the comparative examples 1-2 and examples 1-2 soaked for 0 min, 5 min and 10 min. Specifically, three bags of soaked samples were taken and the bag mouths were cut open, placed in a 20 mL sealed headspace bottle, equilibrated at 70°C, enriched and extracted for 60 min, and desorbed at 230°C for 3 min.

[0046] The GC-O conditions were as follows: 1. Chromatographic conditions: chromatographic column: RTX-5MS quartz capillary column (30mx0.25mm, 0.25mm); injection port temperature: 250℃, detector temperature: 280℃, carrier gas (nitrogen, purity ≥99.99%) flow rate: 1.0mmin, hydrogen flow rate: 40mL / min, air flow rate: 400m / min; the initial temperature of the temperature program was 60℃, which was increased to 180℃ at 2℃ / min, and then increased to 250℃ at 10℃ / min, and maintained for 3min. The total running time was 70min, and the temperature was not split mode.

[0047] 2. Olfactometer conditions: The transfer line temperature was 170 °C, and the effluent from the chromatographic column entered the detector and the olfactometer in a 1:1 split mode at the end of the capillary.

[0048] Three people with sensory evaluation experience will conduct an olfactory analysis test to describe the aroma components they smell (aroma type and aroma intensity), where the aroma intensity is divided into three levels: "1" represents weak aroma; "5" represents medium aroma intensity; "10" represents high aroma intensity. If at least two sniffers smell the aroma at the same retention time, the aroma substance at that retention time is determined to be a valid result, and the final aroma intensity is the average of the aroma intensities smelled by the three sniffers. The analysis results are as follows: Figure 2 and Figure 3 As shown, Figure 2 It is the olfactory analysis result of Example 1 and Comparative Example 1, Figure 3 It is the olfactory analysis result of Example 2 and Comparative Example 2.

[0049] analyze Figure 2 It can be seen that 11 characteristic aroma components were smelled in both Example 1 and Comparative Example 1, and the aroma intensity gradually weakened with the extension of the soaking time. From the weakening rate, the intensity of each aroma component in Example 1 was higher than that in Comparative Example 1 when soaked for 5min and 10min, indicating that the aroma loss of Example 1 was relatively slow, which was more conducive to the maintenance of the aroma and was the key to the uniformity of the aroma.

[0050] analyze Figure 3It can be seen that 10 characteristic aroma components can be smelled in both Example 2 and Comparative Example 2. As the soaking time increases, the aroma intensity gradually weakens. Similarly, from the perspective of the weakening rate, the aroma weakening rate of Example 2 is significantly slower than that of Comparative Example 2, indicating that the aroma loss of Example 2 is relatively slow, which is different from that of Comparative Example 2. Figure 2 The trends shown are consistent.

[0051] The taste evaluation test was conducted in 10 groups, with 10 people in each group, to evaluate the sensory quality of the oral products prepared in Examples 1 and 2 and Comparative Examples 1 and 2. Evaluation indicators are as follows: Figure 4 shown.

[0052] The sensory quality evaluation results of the oral products of each group of Examples 1 and 2 and Comparative Examples 1 and 2 were statistically analyzed, and the average value of each result was taken. The results are as follows: Figure 5 shown.

[0053] analyze Figure 5 It can be seen that the examples and the comparative examples have similar scores in terms of sweetness, coolness and astringency. However, in terms of the evaluation of the feeling of being topped up, mouth irritation and aroma uniformity, the examples are superior to the comparative examples, which has a certain correspondence with the nicotine release results and the aroma olfactory results, further illustrating that compared with the traditional preparation method, the preparation method using micro-pellet drug coating can obtain a sensory experience of comfortable taste, low mouth irritation and good aroma uniformity through the sustained release of nicotine and flavors.

[0054] The above embodiments are merely preferred implementations of the present invention. Any simple modification, amendment and substitution of the above embodiments based on the technical essence of the present invention shall fall within the scope of the technical solution of the present invention.

Claims

1. A method for preparing a pellet-type oral cigarette, characterized in that: The following steps are involved: S1 takes a binder, nicotine salt, a pH adjuster, a sweetener, a cooling agent and a flavor to prepare a spray liquid; S2 is based on the combination of centrifugal granulation and fluidization, and uses a spray liquid to coat the medicinal pellet core to obtain wet pellets; The coating treatment method is specifically performed as follows: S21 takes the medicinal pellet core as the masterbatch and adds it into the coating machine; The S22 medicinal pill core is driven by the coating machine turntable to perform centrifugal motion. At this time, the spray liquid, filler and preservative are sprayed into the coating machine through the peristaltic pump, so that the pill core grows; S23 spraying is finished, lubricant is added to obtain wet pellets; S3: sieving the wet pellets to obtain pellets with a particle size of 300-1500 μm; S4: drying the micro-pellets and bagging them to obtain a snus product.

2. The method for preparing the micro-pellet type buccal cigarette according to claim 1, characterized in that: The method for preparing the spray liquid, the specific operation is as follows: S11: dissolving a binder in pure water to obtain a binder solution; S12: Add nicotine salt, pH adjuster, sweetener, cooling agent and flavor to the adhesive solution in sequence, and stir at room temperature for 10 to 20 minutes until the mixture is completely mixed.

3. The method for preparing the micro-pellet type buccal cigarette according to claim 2, characterized in that: The binder is at least one of povidone, sodium carboxymethyl cellulose, sodium carboxymethyl starch, hydroxypropyl methyl cellulose, methyl cellulose, ethyl cellulose and microcrystalline cellulose; The nicotine salt is at least one of pure nicotine, nicotine tartrate, nicotine tartrate dihydrate, nicotine levulinate, nicotine lactate, nicotine salicylate, nicotine benzoate, nicotine malate and nicotine citrate.

4. The method for preparing the micro-pellet type buccal cigarette according to claim 3, characterized in that: The pH regulator is at least one of sodium hydroxide, potassium hydroxide, sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, sodium phosphate, disodium hydrogen phosphate, sodium acetate, potassium acetate, sodium pyrophosphate, potassium phosphate, dipotassium hydrogen phosphate, calcium hydrogen phosphate, potassium polymetaphosphate, sodium citrate, potassium citrate, sodium gluconate and diammonium hydrogen phosphate.

5. The method for preparing the micro-pellet type buccal cigarette according to claim 4, characterized in that: The sweetener is at least one of monosaccharide, disaccharide, trisaccharide, polysaccharide, polyol, acesulfame potassium, aspartame, sucralose and neotame; the cooling agent is any one of WS-3, WS-5, WS-10, WS-12, WS-23, WS-27 and menthol; The flavor is any one of strawberry, watermelon, mango, grape, banana, lemon, orange, blueberry, raspberry, mint and coffee flavor.

6. The method for preparing the micro-pellet type buccal cigarette according to claim 1, characterized in that: The particle size of the medicinal pill core is 100-800 μm, and the medicinal pill core is at least one of a microcrystalline cellulose pill core and a sucrose pill core.

7. The method for preparing the micro-pellet type buccal cigarette according to claim 1, characterized in that: In S22, the turntable speed is 200-400r / min, the fan speed is 1000~3000r / min, the inlet air temperature is 40~80℃, the atomization pressure is 0.1~0.5MPa, and the peristaltic pump speed is 2~30r / min; The filler is at least one of mannitol, lactose, isomaltulose, sorbitol, maltodextrin, microcrystalline cellulose and pregelatinized starch; the preservative is at least one of potassium sorbate, sodium benzoate and ethyl paraben; and the lubricant is at least one of magnesium stearate, talc and silicon dioxide.

8. The method for preparing the micro-pellet type buccal cigarette according to claim 1, characterized in that: The sieving method is specifically operated as follows: the wet pellets are sifted using a layer screen to screen out pellet particles with a particle size of 300-1500 μm; A sieve with a mesh size of 16 to 50 is used as the layer sieve.

9. The method for preparing the micro-pellet type buccal cigarette according to claim 1, characterized in that: The drying method is specifically operated as follows: the screened pellet particles are placed in a coating machine and dried for 5 to 20 minutes, the inlet air temperature is 40 to 80°C, and the fan speed is 1000 to 3000 r / min.

10. A buccal tobacco product, produced by the method for preparing a micro-pellet-type buccal tobacco according to any one of claims 1 to 9, characterized in that: The oral tobacco product is composed of the following components by weight: 15% to 50% medicinal pellets, 1% to 30% nicotine salt, 1% to 30% adhesive, 10% to 70% filler, 0.1% to 1% lubricant, 1% to 15% sweetener, 1% to 10% flavor, 0.5% to 3% pH adjuster, 0.01% to 1% cooling agent, 0.05% to 1% preservative, and 5% to 10% pure water.

Images