Sterile feeding isolator for medicine preparation
By introducing ventilation sterilization and scraping mechanisms into the sterile feeding isolator, air purification is performed using gasified hydrogen peroxide sterilization and filter nets, bacterial pollution problems are solved, ensuring the sterile environment inside the isolator and the long-term stability of the equipment. .
Patent Information
- Application Number
- CN202411506652.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-28
- Publication Date
- 2024-12-17
AI Technical Summary
Existing sterile feeding isolators are prone to bacterial contamination during operation, especially because tiny particles or aerosols generated during material mixing may carry bacteria, and improper maintenance or degradation of high-efficiency filters may lead to bacteria penetration, affecting Sterile environment of isolators.
The ventilation and sterilization mechanism and a scraping mechanism are adopted. The ventilation and sterilization mechanism includes a ventilation device and a suction mechanism. The air is purified by gasified hydrogen peroxide sterilization and filter screen. The scraping mechanism is cleaned by rotating drivers, transmission rods and fan blades. Filter the dust on the mesh to ensure the sterility of the air and materials.
Effectively prevent bacterial contamination inside the isolator, maintain a sterile environment, prevent cross-infection, extend the service life of the equipment, and improve the purification effect of air and materials.
Smart Images
Figure CN119139991A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of drug preparation, in particular to a sterile feeding isolator for drug preparation. Background Art
[0002] In the process of drug preparation, aseptic feeding isolators play a vital role. They are designed to mix and operate materials in a strict aseptic environment to ensure the safety and effectiveness of drugs. However, in the existing technology, although aseptic feeding isolators have made certain progress, they still face a series of challenges in actual operation, one of the most critical issues is the possible bacterial contamination inside the isolator.
[0003] Aseptic feeding isolators are usually designed to have a completely closed controlled environment, with key operating areas that meet Class A standards. They are mainly composed of key components such as the main frame, high-efficiency filters, operating units, environmental detection systems, control systems, and cleaning units. These components work together to provide a controlled environment that allows operators to physically intervene and achieves biological environmental isolation. However, in actual operations, when materials are mixed in the isolator, tiny particles or aerosols may be generated, which may carry bacteria and pose a threat to the sterile environment inside the isolator.
[0004] In addition, although isolators are usually equipped with high-efficiency filters to filter and purify the air entering the isolator, the filter itself may also pose certain risks. For example, if the filter is not properly maintained or its performance deteriorates, it may cause microorganisms such as bacteria to penetrate the filter and enter the isolator. Summary of the invention
[0005] In view of the above problems, a sterile feeding isolator for drug preparation is provided, which solves the problems of bacteria breeding in the isolator and excessive impurities in the air entering the isolator through a ventilation and sterilization mechanism and a scraping mechanism.
[0006] In order to solve the problems of the prior art, the present invention provides an aseptic feeding isolator for drug preparation, comprising a base, an auxiliary material tank arranged on the base, an isolator body installed on the base, a hopper arranged in the isolator body for infiltrating liquid wax discharged from the auxiliary material tank, a filter arranged on the base for filtering the liquid wax, a first material conveying pipe for conveying materials, a pipeline emulsifier arranged on the base and used for dispersing the material and liquid wax in the hopper, a preparation tank installed on the base and used for mixing the materials, and a ventilation and sterilization mechanism arranged on the isolator body and used for aseptic treatment of the inside of the isolator body, the ventilation and sterilization mechanism comprising a ventilation device and an air suction mechanism arranged on the isolator body, and a filter screen arranged on the ventilation device.
[0007] Preferably, the main body of the aseptic feeding isolator for drug preparation also includes a scraping mechanism arranged on the ventilation device and used to clean dust on the filter screen; the scraping mechanism includes a first rotary drive, a transmission rod and fan blades; the first rotary drive is arranged on the ventilation device; the transmission rod is arranged at the output end of the first rotary drive; and the fan blades are arranged on the transmission rod.
[0008] Preferably, the scraping mechanism also includes a second rotating rod, a first transmission belt and a contact rotating sleeve; the second rotating rod is rotatably arranged on the ventilation device; the first transmission belt is respectively sleeved on the transmission rod and the second rotating rod; the contact rotating sleeve is rotatably arranged on the ventilation device and is located above the second rotating rod.
[0009] Preferably, the scraping mechanism also includes a rotating block, an elastic support sheet and a contact tooth block; the rotating block is rotatably arranged on the second rotating rod; the elastic support sheet is arranged on the second rotating rod and is used to drive the rotating block to tilt and swing; the contact tooth block is arranged on the contact rotating sleeve, and the contact tooth block is used to contact the rotating block and cause the contact rotating sleeve to rotate.
[0010] Preferably, the scraping mechanism also includes a fixed limiting block, a swing block and a travel block; the fixed limiting block is arranged on the ventilation device and has a pair; the swing block is arranged on the fixed limiting block in the horizontal linear sliding direction, and the swing block and the fixed limiting block are clearance-matched; the travel block is arranged on the contact rotating sleeve and slides inside the swing block.
[0011] Preferably, the scraping mechanism further comprises a connecting block and a cleaning plate; the connecting block is arranged on the swing block and has a plurality of them; the cleaning plate is arranged on the connecting block and is located above the filter screen.
[0012] Preferably, the aseptic feeding isolator for drug preparation also includes a mixing mechanism arranged in the preparation tank and used to mix the materials; the mixing mechanism includes a second rotary driver, an output rotary rod and a first stirring rod; the second rotary driver is arranged on the preparation tank; the output rotary rod is arranged on the preparation tank, and the input end of the output rotary rod is connected to the output end of the second rotary driver through a coupling; the first stirring rod is arranged on the output rotary rod and has a plurality of them, and the first stirring rod is used to evenly mix the materials in the preparation tank.
[0013] Preferably, the mixing mechanism also includes a bearing rotating sleeve, a rotating rod, a contact block and a second transmission belt; the bearing rotating sleeve is rotatably arranged on the preparation tank; the rotating rod is rotatably arranged on the preparation tank; the contact block is arranged on the rotating rod and has a pair, the contact block is coaxially fixed with the rotating rod and is used for intermittent contact with the bearing rotating sleeve; the second transmission belt is respectively sleeved on the output rotating rod and the rotating rod.
[0014] Preferably, the mixing mechanism also includes a scraper and a bottom scraper block; the scraper is arranged on the bearing rotating sleeve and has a pair, and the scraper is used to scrape and clean the material attached to the inside of the preparation tank; the bottom scraper is arranged on the scraper and contacts the bottom of the preparation tank.
[0015] Preferably, the mixing mechanism further comprises a second stirring rod and a contact collision rod; the second stirring rod is arranged on the scraper and is a pair, and the second stirring rods are respectively located between the first stirring rods; and the contact collision rod is arranged on the second stirring rod and is a plurality of the second stirring rods.
[0016] Compared with the prior art, the present invention has the following beneficial effects:
[0017] 1. The present invention provides a ventilation and sterilization mechanism and a scraping mechanism to continuously purify and ventilate the inside of the isolator body, thereby maintaining a relatively sterile environment inside the isolator body, helping to prevent contamination and cross infection, and further ensuring that there are no bacteria inside the isolator body.
[0018] 2. The present invention provides a first rotary drive, a transmission rod and a fan blade, so that air can be introduced into the purifier from the filter screen. Finally, the air is filtered through the purifier to prevent bacteria in the air from entering the interior of the isolator body, thereby achieving an air filtering effect.
[0019] 3. The present invention provides a second rotating rod, a first transmission belt and a contact rotating sleeve, and the first transmission belt drives the second rotating rod to rotate, thereby completing the transmission of the rotating force.
[0020] 4. The present invention provides a connecting block and a cleaning plate to prevent dust from entering the purifier when the cleaning plate is scraping and cleaning the filter, thereby affecting the purifying effect of the purifier on bacteria in the air, thereby ensuring the sterility of the air entering the isolator body.
[0021] 5. The present invention can prevent the material from adhering to the inner wall of the preparation tank and accumulating and settling at the bottom of the preparation tank by setting a mixing mechanism. On the other hand, it can also prevent the scraper from always contacting the inner wall of the preparation tank and causing continuous damage to the inner wall of the preparation tank, thereby increasing the service life of the preparation tank in disguise. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 It is a three-dimensional structural diagram from the first perspective of a sterile feeding isolator for drug preparation.
[0023] Figure 2 It is a stereoscopic structural diagram of a sterile feeding isolator for drug preparation from a second perspective.
[0024] Figure 3It is a partial three-dimensional structural cross-sectional view of a sterile feeding isolator for drug preparation.
[0025] Figure 4 It is a partial three-dimensional structural cross-sectional view of a sterile feeding isolator for drug preparation.
[0026] Figure 5 yes Figure 3 Enlarged structural diagram at point A in the middle.
[0027] Figure 6 The present invention is a three-dimensional structural diagram of a scraping mechanism of a sterile feeding isolator for drug preparation.
[0028] Figure 7 The present invention is a three-dimensional structural diagram of a second rotating rod and a contact rotating sleeve of a sterile feeding isolator for drug preparation in an exploded state.
[0029] Figure 8 yes Figure 3 Enlarged structural diagram at point B in the middle.
[0030] Fig. 9 yes Figure 7 Enlarged structural diagram at center C.
[0031] Fig.10 It is a three-dimensional structural diagram of a mixing mechanism of a sterile feeding isolator for drug preparation.
[0032] Fig.11 It is a three-dimensional structural diagram of a contact collision rod of a sterile feeding isolator for drug preparation.
[0033] The numbers in the figure are: 1, base; 11, auxiliary material tank; 2, isolator body; 21, hopper; 3, first material conveying pipe; 31, second material conveying pipe; 32, third material conveying pipe; 4, pipeline emulsifier; 5, preparation tank; 6, ventilation and sterilization mechanism; 61, ventilation device; 62, suction mechanism; 621, filter; 622, purifier; 63, filter screen; 7, scraping mechanism; 71, first rotary drive; 72, transmission rod; 73, fan blade; 74, second rotary rod; 75, first transmission belt; 76. contact rotating sleeve; 77. rotating block; 78. elastic supporting sheet; 79. contact tooth block; 791. fixed limiting block; 792. swing block; 793. travel block; 794. connecting block; 795. cleaning plate; 8. mixing mechanism; 81. second rotating driver; 82. output rotating rod; 83. first stirring rod; 84. bearing rotating sleeve; 85. rotating rod; 86. contact block; 87. second transmission belt; 88. scraper; 89. bottom scraping block; 891. second stirring rod; 892. contact collision rod. DETAILED DESCRIPTION
[0034] In order to further understand the features, technical means, specific objectives and functions of the present invention, the present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.
[0035] See also Figure 1-Figure 3 As shown, a sterile feeding isolator for drug preparation includes a base 1, an auxiliary material tank 11 arranged on the base 1, an isolator body 2 installed on the base 1, a hopper 21 arranged in the isolator body 2 for infiltrating the liquid wax discharged from the auxiliary material tank 11, a filter 621 arranged on the base 1 for filtering the liquid wax, a first material conveying pipe 3 for conveying materials, a pipeline emulsifier 4 arranged on the base 1 and used to disperse the material and liquid wax in the hopper 21, a preparation tank 5 installed on the base 1 and used to mix the materials, and a ventilation and sterilization device arranged on the isolator body 2 and used to sterilize the inside of the isolator body 2. The ventilation and sterilization mechanism 6 includes a ventilation device 61 and an air suction mechanism 62 arranged on the isolator body 2, and a filter screen 63 arranged on the ventilation device 61. A filter 621 for purifying liquid wax is arranged on the base 1. The first material conveying pipe 3 is respectively connected to the auxiliary material tank 11 and the filter 621, the second material conveying pipe 31 is respectively connected to the discharge end of the filter 621 and the feed end of the hopper 21, the feed end of the third material conveying pipe 32 is connected to the discharge end of the hopper 21, and the discharge end of the third material conveying pipe 32 is connected to the feed end of the preparation tank 5. A purifier 622 connected to the ventilation device 61 is arranged on the isolator body 2.
[0036] First, liquid wax is added to the auxiliary material tank 11, and the liquid wax enters the filter 621 after passing through the auxiliary material tank 11 and the first material conveying pipe 3. The filter 621 has a pair, and the filter 621 can filter the liquid wax twice. The filtered liquid wax is first added to one-fourth of the hopper 21, and then the raw material is added to the hopper 21. After entering, a layer of liquid wax is laid on the raw material. At this time, the material and liquid wax in the hopper 21 can be fully infiltrated. The infiltrated material enters the pipeline emulsifier 4 through the first material conveying pipe 3. The pipeline emulsifier 4 can disperse and homogenize the soaked material. During the emulsification and dispersion process, the hopper 21 is cleaned to keep the hopper 21 clean and tidy, and then the above operation is repeated. Finally, the mixture of liquid wax and raw materials will enter the preparation tank 5 through the first material conveying pipe 3 to complete the mixing and preparation of the materials. When the material and liquid wax are mixed in the hopper 21, the ventilation device 61 is started, and then the air enters the filter 63 through the ventilation device 61 and the filter 63. The filter 63 can filter the air in the air. Dust, impurities and bacteria are filtered, and the filtered air enters the isolator body 2 and forms a vertical downward flow. The isolator body 2 is provided with hydrogen peroxide sterilization, and hydrogen peroxide sterilization is preferably vaporized hydrogen peroxide sterilization. The cell structure of microorganisms is destroyed by oxidation to achieve a complete sterilization effect. During the sterilization process, vaporized hydrogen peroxide is reduced to water and oxygen, without harmful residues, and is harmless to operators and the environment. At the same time, the suction mechanism 62 can timely extract the air inside the isolator body 2, and effective ventilation can be performed. Through continuous air purification and ventilation, a relatively sterile environment can be maintained inside the isolator body 2, which helps to prevent pollution and cross infection, and further ensure that there are no bacteria inside the isolator body 2. The dust at the filter 63 can be scraped and discharged by the scraping mechanism 7, so that continuous air purification and ventilation can be performed in the isolator body 2, so that a relatively sterile environment can be maintained inside the isolator body 2, which helps to prevent pollution and cross infection, and further ensure that there are no bacteria inside the isolator body 2.
[0037] See also Figure 2-Figure 4 As shown, the main body 2 of the aseptic feeding isolator for drug preparation also includes a scraping mechanism 7 arranged on the ventilation device 61 and used to clean the dust on the filter 63; the scraping mechanism 7 includes a first rotary driver 71, a transmission rod 72 and a fan blade 73; the first rotary driver 71 is arranged on the ventilation device 61; the transmission rod 72 is arranged at the output end of the first rotary driver 71; the fan blade 73 is arranged on the transmission rod 72, and the first rotary driver 71 is preferably a DC motor, and the first rotary driver 71 can be controlled by a controller to rotate forward or reverse.
[0038] When air needs to be introduced into the isolator body 2, the first rotary driver 71 is started first, thereby driving the transmission rod 72 and the fan blades 73 to rotate, so that air can be introduced from the filter screen 63 into the purifier 622. Finally, the air is filtered through the purifier 622 to prevent bacteria in the air from entering the interior of the isolator body 2, thereby achieving the filtering effect of the air.
[0039] See also Figure 5 and Figure 6 As shown, the scraping mechanism 7 also includes a second rotating rod 74, a first transmission belt 75 and a contact rotating sleeve 76; the second rotating rod 74 is rotatably set on the ventilation device 61; the first transmission belt 75 is respectively sleeved on the transmission rod 72 and the second rotating rod 74; the contact rotating sleeve 76 is rotatably set on the ventilation device 61 and is located above the second rotating rod 74.
[0040] During the rotation of the transmission rod 72 , the second rotation rod 74 can be driven to rotate by the first transmission belt 75 , and the transmission of the rotation force is completed at this time.
[0041] See also Figure 7-Figure 9 As shown, the scraping mechanism 7 also includes a rotating block 77, an elastic support sheet 78 and a contact tooth block 79; the rotating block 77 is rotatably arranged on the second rotating rod 74; the elastic support sheet 78 is arranged on the second rotating rod 74 and is used to drive the rotating block 77 to tilt and swing; the contact tooth block 79 is arranged on the contact rotating sleeve 76, and the contact tooth block 79 is used to contact the rotating block 77 and cause the contact rotating sleeve 76 to rotate.
[0042] When the second rotating rod 74 rotates, during this process, the elastic support sheet 78 can make the rotating block 77 always contact with the contact tooth block 79, and when the contact tooth block 79 and the contact rotating sleeve 76 are not driven to rotate, the contact rotating sleeve 76 does not rotate when the first rotating driver 71 is started and air passes through the filter screen 63. When it is necessary to drive the contact rotating sleeve 76 to rotate, the first rotating driver 71 rotates in the opposite direction, and the second rotating rod 74 can be driven to rotate in the opposite direction through the first transmission belt 75. During rotation, the elastic support sheet 78 can cause the rotating block 77 to engage with the contact tooth block 79, and cause the contact tooth block 79 and the contact rotating sleeve 76 to rotate, so that the contact rotating sleeve 76 can be driven to rotate only when the second rotating rod 74 rotates in the opposite direction, and the contact rotating sleeve 76 does not rotate when the transmission rod 72 rotates forward.
[0043] See also Figure 6As shown, the scraping mechanism 7 also includes a fixed limiting block 791, a swing block 792 and a travel block 793; the fixed limiting block 791 is arranged on the ventilation device 61 and has a pair; the swing block 792 is arranged on the fixed limiting block 791 in a horizontal linear sliding direction, and the swing block 792 and the fixed limiting block 791 are clearance-matched; the travel block 793 is arranged on the contact rotating sleeve 76 and slides in the swing block 792, and a displacement groove is provided on the swing block 792 for limiting the rotation and sliding of the travel block 793.
[0044] When the contact rotating sleeve 76 rotates, it can drive the travel block 793 to perform synchronous rotational motion. When the travel block 793 rotates, it can perform rotational swinging and sliding inside the swing block 792. During this process, the swing block 792 can be restricted by the fixed limiting block 791 with clearance fit and perform reciprocating sliding in the horizontal straight line direction.
[0045] See also Figure 6 As shown, the scraping mechanism 7 also includes a connecting block 794 and a cleaning plate 795 ; the connecting block 794 is arranged on the swing block 792 and has a plurality of them; the cleaning plate 795 is arranged on the connecting block 794 and is located above the filter screen 63 .
[0046] During the reciprocating sliding of the swing block 792 in the horizontal straight direction, the connecting block 794 and the cleaning plate 795 can be driven to scrape and clean the dust attached to the filter 63, and during the cleaning process, the fan blades 73 and the transmission rod 72 rotate in opposite directions, and the dust dropped during the cleaning process can be blown out of the ventilation device 61, thereby preventing the cleaning plate 795 from scraping and cleaning the filter 63. The dust will still enter the purifier 622, thereby affecting the purification effect of the purifier 622 on bacteria in the air, thereby ensuring the sterility of the air entering the isolator body 2.
[0047] See also Fig.10 and Fig.11 As shown, the aseptic feeding isolator for drug preparation also includes a mixing mechanism 8 arranged in the preparation tank 5 and used to mix materials; the mixing mechanism 8 includes a second rotary driver 81, an output rotary rod 82 and a first stirring rod 83; the second rotary driver 81 is arranged on the preparation tank 5; the output rotary rod 82 is arranged on the preparation tank 5, and the input end of the output rotary rod 82 is connected to the output end of the second rotary driver 81 through a coupling; the first stirring rod 83 is arranged on the output rotary rod 82 and has a plurality of them, and the first stirring rod 83 is used to evenly mix the materials in the preparation tank 5.
[0048] When the materials in the preparation tank 5 need to be mixed evenly, the second rotary driver 81 is started first, and then the second rotary driver 81 drives the output rotary rod 82 and the first stirring rod 83 to rotate. During this process, the first stirring rod 83 can mix the materials in the preparation tank 5 evenly and effectively.
[0049] See also Fig.10 and Fig.11 As shown, the mixing mechanism 8 also includes a bearing rotating sleeve 84, a rotating rod 85, a contact block 86 and a second transmission belt 87; the bearing rotating sleeve 84 is rotatably set on the preparation tank 5; the rotating rod 85 is rotatably set on the preparation tank 5; the contact block 86 is set on the rotating rod 85 and has a pair, the contact block 86 is coaxially fixed with the rotating rod 85 and is used for intermittent contact with the bearing rotating sleeve 84; the second transmission belt 87 is respectively sleeved on the output rotating rod 82 and the rotating rod 85.
[0050] During the rotation of the output rotating rod 82, the rotating rod 85 can be driven to perform synchronous rotation movement through the second transmission belt 87. When the rotating rod 85 rotates, it can drive the contact block 86 to form intermittent contact with the bearing rotating sleeve 84, and cause the bearing rotating sleeve 84 to rotate along the preparation tank 5, thereby achieving an intermittent contact rotation effect on the bearing rotating sleeve 84.
[0051] See also Fig.10 and Fig.11 As shown, the mixing mechanism 8 also includes a scraper 88 and a bottom scraper block 89; the scraper 88 is arranged on the bearing rotating sleeve 84 and has a pair, and the scraper 88 is used to scrape and clean the materials attached to the inside of the preparation tank 5; the bottom scraper is arranged on the scraper 88 and contacts the bottom of the preparation tank 5.
[0052] During the rotation process when the bearing rotating sleeve 84 contacts the contact block 86, the scraper 88 and the bottom scraper block 89 can be caused to rotate synchronously, so that when the contact block 86 contacts the bearing rotating sleeve 84, the scraper 88 and the bottom scraper block 89 can intermittently scrape the inner wall and bottom of the preparation tank 5, which can prevent the material from adhering to the inner wall of the preparation tank 5 and prevent the material from accumulating and settling at the bottom of the preparation tank 5. On the other hand, it can also prevent the scraper 88 from always contacting the inner wall of the preparation tank 5 and causing continuous damage to the inner wall of the preparation tank 5, thereby increasing the service life of the preparation tank 5 in disguise.
[0053] See also Fig.11 As shown, the mixing mechanism 8 also includes a second stirring rod 891 and a contact collision rod 892; the second stirring rod 891 is arranged on the scraper 88 and has a pair, and the second stirring rod 891 is respectively located between the first stirring rods 83; the contact collision rod 892 is arranged on the second stirring rod 891 and has a plurality of them.
[0054] During the rotation of the scraper 88 and the bearing rotating sleeve 84, the second stirring rod 891 and the contact collision rod 892 can be driven to perform synchronous rotational motion. When the contact collision rod 892 rotates intermittently, it can cooperate with the first stirring rod 83 to increase the efficiency of mixing the materials inside the preparation tank 5, improve the mixing effect of the materials, and avoid the phenomenon of material stratification caused by single stirring.
[0055] Working principle: First, liquid wax is added to the auxiliary material tank 11, enters the filter 621 through the first material conveying pipe 3 for two filtrations, and then is mixed with the raw material in the hopper 21, and a layer of liquid wax is laid to fully infiltrate. The infiltrated material enters the pipeline emulsifier 4 for dispersion and homogenization. At the same time, the ventilation device 61 is started, and the air enters the isolator body 2 after being filtered by the filter 63, forming a vertical downward flow, and the sterile environment is maintained by sterilizing with gasified hydrogen peroxide. The suction mechanism 62 is responsible for timely extracting the internal air for effective ventilation. When it is necessary to introduce air into the isolator body 2, the first rotary driver 71 is started, driving the transmission rod 72 and the fan blade 73 to rotate, and introducing the air from the filter 63 into the purifier 622 for filtration. During the rotation of the transmission rod 72, the second rotating rod 74 is driven to rotate by the first transmission belt 75. At this time, the elastic support sheet 78 ensures that the rotating block 77 is in contact with the contact tooth block 79, but does not drive it to rotate. When the contact rotating sleeve 76 needs to be driven to rotate, the first rotating driver 71 rotates in the opposite direction, and drives the second rotating rod 74 to rotate in the opposite direction through the first transmission belt 75, thereby driving the contact tooth block 79 and the contact rotating sleeve 76 to rotate. When the contact rotating sleeve 76 rotates, it drives the travel block 793 and other components to scrape and clean the filter screen 63, and at the same time, the fan blade 73 and the transmission rod 72 rotate in the opposite direction to blow out the dust.
[0056] During the rotation of the output rotating rod 82, the rotating rod 85 is driven to rotate by the second transmission belt 87, and then the contact block 86 is driven to form intermittent contact with the bearing rotating sleeve 84, so that the bearing rotating sleeve 84 rotates. During the contact process, the scraper 88 and the scraping block 89 intermittently scrape the inner wall and bottom of the preparation tank 5 to prevent material adhesion and accumulation. At the same time, the contact collision rod 892 cooperates with the stirring rod 83 to improve the material mixing efficiency.
[0057] The above embodiments only express one or several implementation modes of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for those of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the attached claims.
Claims
1. A sterile feeding isolator for drug preparation, comprising a base (1), an auxiliary material tank (11) arranged on the base (1), an isolator body (2) installed on the base (1), a hopper (21) arranged in the isolator body (2) for infiltrating liquid wax discharged from the auxiliary material tank (11), a filter (621) arranged on the base (1) for filtering the liquid wax, a first material conveying pipe (3) for conveying materials, a pipeline emulsifier (4) arranged on the base (1) for dispersing materials and liquid wax in the hopper (21), a preparation tank (5) installed on the base (1) for mixing materials, and a ventilation and sterilization mechanism (6) arranged on the isolator body (2) for aseptically treating the interior of the isolator body (2); It is characterized in that The ventilation and sterilization mechanism (6) comprises a ventilation device (61), an air suction mechanism (62) arranged on the isolator body (2), and a filter screen (63) arranged on the ventilation device (61).
2. A sterile feeding isolator for drug preparation according to claim 1, It is characterized in that The main body (2) of the aseptic feeding isolator for drug preparation further comprises a scraping mechanism (7) arranged on the ventilation device (61) and used for cleaning dust on the filter screen (63); the scraping mechanism (7) comprises a first rotary driver (71), a transmission rod (72) and a fan blade (73); the first rotary driver (71) is arranged on the ventilation device (61); the transmission rod (72) is arranged at the output end of the first rotary driver (71); and the fan blade (73) is arranged on the transmission rod (72).
3. A sterile feeding isolator for drug preparation according to claim 1, It is characterized in that The scraping mechanism (7) further comprises a second rotating rod (74), a first transmission belt (75) and a contact rotating sleeve (76); the second rotating rod (74) is rotatably arranged on the ventilation device (61); the first transmission belt (75) is respectively sleeved on the transmission rod (72) and the second rotating rod (74); and the contact rotating sleeve (76) is rotatably arranged on the ventilation device (61) and is located above the second rotating rod (74).
4. A sterile feeding isolator for drug preparation according to claim 3, It is characterized in that The scraping mechanism (7) further comprises a rotating block (77), an elastic support sheet (78) and a contact tooth block (79); the rotating block (77) is rotatably arranged on the second rotating rod (74); the elastic support sheet (78) is arranged on the second rotating rod (74) and is used to drive the rotating block (77) to perform tilting and swinging; the contact tooth block (79) is arranged on the contact rotating sleeve (76), and is used to contact the rotating block (77) and cause the contact rotating sleeve (76) to perform rotational movement.
5. A sterile feeding isolator for drug preparation according to claim 1, It is characterized in that The scraping mechanism (7) further comprises a fixed limiting block (791), a swinging block (792) and a travel block (793); the fixed limiting block (791) is arranged on the ventilation device (61) and comprises a pair of the fixed limiting blocks; the swinging block (792) is arranged on the fixed limiting block (791) in a horizontal linear sliding direction, and the swinging block (792) and the fixed limiting block (791) are clearance-matched; the travel block (793) is arranged on the contact rotating sleeve (76) and is located inside the swinging block (792) and slides.
6. A sterile feeding isolator for drug preparation according to claim 5, It is characterized in that The scraping mechanism (7) also includes a connecting block (794) and a cleaning plate (795); the connecting block (794) is arranged on the swing block (792) and has a plurality of them; the cleaning plate (795) is arranged on the connecting block (794) and is located above the filter screen (63).
7. A sterile feeding isolator for drug preparation according to claim 1, It is characterized in that The aseptic feeding isolator for drug preparation further comprises a mixing mechanism (8) arranged in the preparation tank (5) and used for mixing materials; the mixing mechanism (8) comprises a second rotary driver (81), an output rotary rod (82) and a first stirring rod (83); the second rotary driver (81) is arranged on the preparation tank (5); the output rotary rod (82) is arranged on the preparation tank (5), and the input end of the output rotary rod (82) is connected to the output end of the second rotary driver (81) through a coupling; the first stirring rod (83) is arranged on the output rotary rod (82) and has a plurality of them, and the first stirring rod (83) is used for uniformly mixing the materials in the preparation tank (5).
8. A sterile feeding isolator for drug preparation according to claim 1, It is characterized in that The mixing mechanism (8) further comprises a bearing rotating sleeve (84), a rotating rod (85), a contact block (86) and a second transmission belt (87); the bearing rotating sleeve (84) is rotatably mounted on the preparation tank (5); the rotating rod (85) is rotatably mounted on the preparation tank (5); a pair of contact blocks (86) are mounted on the rotating rod (85), the contact blocks (86) are coaxially fixed with the rotating rod (85) and are used for intermittent contact with the bearing rotating sleeve (84); and the second transmission belt (87) is respectively mounted on the output rotating rod (82) and the rotating rod (85).
9. A sterile feeding isolator for drug preparation according to claim 8, It is characterized in that The mixing mechanism (8) further comprises a scraper (88) and a bottom scraper block (89); the scraper (88) is arranged on the bearing rotating sleeve (84) and comprises a pair of scrapers (88), and the scraper (88) is used to scrape and clean the material attached to the inside of the preparation tank (5); the bottom scraper is arranged on the scraper (88) and contacts the bottom of the preparation tank (5).
10. A sterile feeding isolator for drug preparation according to claim 9, It is characterized in that The mixing mechanism (8) further comprises a second stirring rod (891) and a contact collision rod (892); the second stirring rod (891) is arranged on the scraper (88) and is in a pair, and the second stirring rods (891) are respectively located between the first stirring rods (83); and the contact collision rods (892) are arranged on the second stirring rod (891) and are in a plurality.