Automatic-cleaning enzymolysis furnace for polypeptide preparation

Abstract

The invention relates to the technical field of enzymolysis, in particular to an automatic-cleaning enzymolysis furnace for polypeptide preparation, which comprises an enzymolysis furnace body, a stirring structure, a driving mechanism and an automatic cleaning mechanism, the enzymolysis furnace body comprises a tank body and a cover body, and a plurality of cleaning windows are formed in the tank body in an annular array; the stirring structure is arranged in the tank body; the driving mechanism is used for driving the stirring structure to move; the automatic cleaning mechanism comprises a plurality of high-pressure water pipes, the high-pressure water pipes correspond to the cleaning windows respectively, each high-pressure water pipe comprises a cleaning part and a water supply part, the cleaning parts are tightly attached to the cleaning windows, a plurality of spray heads are arranged on the cleaning parts, all the spray heads face the interior of the tank body, and the spray heads are arranged along buses of the high-pressure water pipes; the water supply part is located at the lower end of the cleaning part and externally connected with a pressurization water supply device. The stirring structure, the driving mechanism and the automatic cleaning mechanism are arranged, so that the cleaning effect of cleaning water on the inner wall of the tank body, the stirring shaft and the stirring blades is improved.

Description

Technical Field

[0001] The invention relates to the technical field of enzymolysis, in particular to an enzymolysis furnace for preparing polypeptides which can be automatically cleaned. Background Art

[0002] The enzymatic hydrolysis furnace for polypeptide preparation is a device specially used for enzymatic hydrolysis reaction in the process of polypeptide preparation. Enzymatic hydrolysis is a decomposition catalyzed by enzymes, which is specifically manifested as the process of decomposing macromolecular compounds into small molecular compounds.

[0003] The enzymolysis furnace for preparing polypeptides disclosed in Chinese patent CN212533017U has a water injection port on one side of a fixed column connected to a water pipe. Because the water inlet channel, the water injection port and the small nozzle arranged inside the rotating column are connected, water will flow into the small nozzle, forming a beam of water to clean the inner wall of the enzymolysis furnace body during the rotation of the rotating column.

[0004] The above scheme still has the following problems: 1. The water flows from the rotating column toward the inner wall of the enzymolysis furnace body. The distance between the water outlet on the rotating column and the enzymolysis furnace is relatively far, so the impact force of the water flow will be reduced. At the same time, the water outlet on the rotating column moves synchronously with the paddle component. The force of the paddle component hitting the water flow is relatively small, so that the splashing effect of the water flow is relatively poor, resulting in a relatively poor cleaning effect of the water flow on the enzymolysis furnace body. 2. One side surface of the paddle member is in contact with the water flow, while the other side surface of the paddle member is difficult to contact with the water flow, resulting in the other side of the paddle being difficult to clean. Summary of the invention

[0005] In view of the above problems, an automatically cleanable enzymolysis furnace for polypeptide preparation is provided. The invention is provided with a stirring structure, a driving mechanism and an automatic cleaning mechanism, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank, the stirring shaft and the stirring blades.

[0006] In order to solve the problems of the prior art, the present invention provides an automatically cleanable enzymolysis furnace for preparing polypeptides, comprising an enzymolysis furnace body, a stirring structure, a driving mechanism and an automatic cleaning mechanism; the enzymolysis furnace body comprises a tank body and a cover body, a plurality of cleaning windows are provided in a circular array on the tank body, the plurality of cleaning windows penetrate the side wall of the tank body, and the cover body is provided at the upper end of the tank body; the stirring structure is arranged inside the tank body; the driving mechanism is arranged at the upper end of the cover body, and the driving mechanism is used to drive the stirring structure to move; the automatic cleaning mechanism is arranged outside the tank body, the automatic cleaning mechanism comprises a plurality of high-pressure water pipes, the plurality of high-pressure water pipes respectively correspond to the plurality of cleaning windows, the high-pressure water pipe comprises a cleaning part and a water supply part, the cleaning part is closely attached to the cleaning window, a plurality of nozzles are provided on the cleaning part, the plurality of nozzles are all directed toward the inside of the tank body, and the plurality of nozzles are arranged along the busbar of the high-pressure water pipe, the water supply part is located at the lower end of the cleaning part, and the water supply part is externally connected to a pressurized water supply device.

[0007] Preferably, the driving mechanism includes a first driving structure and a second driving structure; the first driving structure is arranged on one side above the cover body, and the first driving structure is used to drive the stirring structure to stir various raw materials in the tank body; the second driving structure is arranged on the other side above the cover body, and the second driving structure is used to drive the stirring structure to clean the inner wall of the tank body.

[0008] Preferably, the driving mechanism also includes a switching structure, which is arranged between the first driving structure and the second driving structure, and the switching structure includes a U-shaped frame, a first connecting structure, a second connecting structure and a synchronous driving structure; the U-shaped frame cover is arranged above the first driving structure and the second driving structure, and the U-shaped frame is connected to the cover body, and the U-shaped frame is symmetrically provided with a first mounting groove and a second mounting groove; the first connecting structure is arranged in the first mounting groove, and the first connecting structure connects the first driving structure to the U-shaped frame; the second connecting structure is arranged in the second mounting groove, and the second connecting structure connects the second driving structure to the U-shaped frame; the synchronous driving structure is arranged on one side of the U-shaped frame, and the synchronous driving structure is used to drive the first driving structure and the second driving structure to move synchronously.

[0009] Preferably, the automatic cleaning mechanism also includes a first mounting bin, a second mounting bin, a first opening and closing mechanism and a rotating mechanism; the first mounting bin is arranged at the bottom of the tank body; the second mounting bin is arranged at the bottom of the first mounting bin; the first opening and closing mechanism is arranged in the first mounting bin, and the first opening and closing mechanism is used to drive a number of high-pressure water pipes away from the cleaning window or close to the cleaning window; the rotating mechanism is arranged in the second mounting bin, and the rotating mechanism is used to drive a number of high-pressure water pipes to rotate so that the nozzles of the high-pressure water pipes are away from the inner side of the tank body.

[0010] Preferably, a strip-shaped sealing block is also provided on the high-pressure water pipe, and the strip-shaped sealing block is arranged along the busbar of the high-pressure water pipe.

[0011] Preferably, the first opening and closing mechanism includes a fixed column, a driving plate, a plurality of driving arm assemblies and a second linear drive, the fixed column is arranged at the bottom of the tank body, and the axis of the fixed column is collinear with the central axis of the tank body; the driving plate is connected to the fixed column through a bearing, the axis of the driving plate is collinear with the axis of the fixed column, and the driving plate has a plurality of corners; the plurality of driving arm assemblies are respectively arranged at a plurality of corners of the driving plate, and the plurality of driving arm assemblies connect the driving plate to the lower ends of a plurality of high-pressure water pipes; the second linear drive is arranged on one side of the driving plate, and the second linear drive is used to push the driving plate to rotate around the axis of the fixed column.

[0012] Preferably, the automatic cleaning mechanism also includes a second opening and closing mechanism, which is arranged inside the cover body, has the same structure as the first opening and closing mechanism, and is connected to the upper ends of several high-pressure water pipes.

[0013] Preferably, the rotating mechanism includes several driven wheels, a synchronous transmission belt, a tensioning structure and a third driving structure; the several driven wheels correspond to several high-pressure water pipes respectively, and the driven gears are installed at the lower ends of the high-pressure water pipes; the synchronous transmission belt is connected to the several driven wheels; the tensioning structure is arranged in the middle of the several driven wheels, and the tensioning structure keeps the synchronous transmission belt in a tensioned state; the third driving structure is arranged in the second installation bin, and the third driving structure is used to drive a driven wheel to rotate.

[0014] Preferably, the rotating mechanism further comprises a synchronous moving structure, which connects the third driving structure to the driving arm assembly.

[0015] Preferably, the automatic cleaning mechanism also includes a fixing mechanism, which is arranged at the bottom of the tank body, and includes two clamping plates and a fourth driving structure; the two clamping plates are respectively arranged at both ends of the driving plate; and the fourth driving structure is arranged between the two clamping plates.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention is provided with a stirring structure, a driving mechanism and an automatic cleaning mechanism. An external pressurized water supply device provides cleaning water into a high-pressure water pipe. High-pressure water is sprayed out from a nozzle. The water flow can be sprayed to the middle of the tank body under the action of high pressure. At the same time, the driving mechanism drives the stirring structure to rotate. The stirring blades rotate at a high speed relative to the inner wall of the tank body, while the water flow is in a stationary state relative to the inner wall of the tank body. The high-speed rotating stirring blades collide with the water flow. The water flow will be hit by the stirring blades and hit the inner wall of the tank body. The water flow hits the inner wall of the tank body and rebounds and contacts the stirring blades again. This is repeated, so that the water flow has a large impact force each time it contacts the inner wall of the tank body and the stirring blades, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body, the stirring shaft and the stirring blades.

[0017] 2. The present invention sets a second driving structure, the first linear drive first drives the mounting block to move from one end of the guide rod to the other end, the mounting block drives the transmission rack to move from one end of the guide rod to the other end, the transmission rack drives the stirring shaft to rotate forward through the driven gear, the stirring shaft drives the stirring blade to rotate forward, one side surface of the stirring blade contacts with the cleaning water, and then the first linear drive drives the mounting block to return to its position, the mounting block drives the stirring shaft to reverse through the transmission rack and the driven gear, the stirring shaft drives the stirring blade to reverse, and the other side surface of the stirring blade contacts with the cleaning water, thereby achieving the cleaning of the surfaces on both sides of the stirring blade.

[0018] 3. The present invention provides a switching structure. When the stirring blade stirs the raw material, the first screw rotates forward, and the two connecting blocks respectively drive the first moving block and the second moving block to move in one direction. The first moving block drives the first rotation driver to move toward the driven gear, and the driving gear is meshed with the driven gear, so that the stirring blade rotates continuously in the opposite direction. When the self-cleaning mechanism is working, the first screw is reversed, and the first moving block and the second moving block move in opposite directions. The driving gear is disengaged from the driven gear, and the transmission rack is meshed with the driven gear, so that the stirring blade swings back and forth, thereby avoiding the problem of mutual interference between the first drive structure and the second drive structure, so that the stirring structure has two working modes. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a stereoscopic diagram of an enzymatic hydrolysis furnace for peptide preparation that can be cleaned automatically.

[0020] Figure 2 The front view of an enzymatic hydrolysis furnace for peptide preparation that can be cleaned automatically.

[0021] Figure 3 yes Figure 2 Cross-sectional view at AA in the middle.

[0022] Figure 4 The present invention is a stereoscopic diagram of a cover, a stirring shaft and a driving mechanism in an enzymatic hydrolysis furnace for preparing polypeptides which can be cleaned automatically.

[0023] Figure 5 The present invention is a stereoscopic diagram of a stirring shaft, a driven gear, a first driving structure and a second driving structure in an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0024] Figure 6 It is a stereoscopic diagram of a switching structure in an enzymatic hydrolysis furnace for peptide preparation that can be automatically cleaned.

[0025] Figure 7 The present invention is a stereoscopic diagram of a high-pressure water pipe, a first installation chamber, a second installation chamber, a first opening and closing mechanism and a rotating mechanism in an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0026] Figure 8 The present invention is a stereoscopic diagram of a high-pressure water pipe, a first opening and closing mechanism, a rotating mechanism and a fixing mechanism in an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0027] Fig. 9 The present invention is a stereoscopic diagram of a medium- and high-pressure water pipe and a first opening and closing mechanism of an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0028] Fig.10 The present invention is a stereoscopic diagram of a cover body, a high-pressure water pipe, a first opening and closing mechanism and a second opening and closing mechanism in an enzymolysis furnace for preparing polypeptides which can be automatically cleaned.

[0029] Fig.11 It is a stereoscopic diagram of a high-pressure water pipe and a rotating mechanism in an enzymatic hydrolysis furnace for peptide preparation that can be cleaned automatically.

[0030] Fig.12 The present invention is a stereoscopic diagram of a high-pressure water pipe, a driving plate, a driving arm assembly, a driven wheel, a third driving structure and a synchronous moving structure in an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0031] Fig.13 The present invention is a stereoscopic diagram of a fixed column, a driving plate and a fixing mechanism in an enzymatic hydrolysis furnace for preparing polypeptides which can be automatically cleaned.

[0032] The numbers in the figure are: 1, enzymolysis furnace body; 11, tank body; 111, cleaning window; 12, cover body; 2, stirring structure; 21, stirring shaft; 211, driven gear; 22, stirring blade; 3, driving mechanism; 31, first driving structure; 311, driving gear; 312, first rotary driver; 32, second driving structure; 321, transmission rack; 322, mounting block; 323, guide structure; 3231, guide rod; 3232, first spring; 324, first linear driver actuator; 33, switching structure; 331, U-shaped frame; 332, first connecting structure; 3321, first U-shaped plate; 3322, first guide crossbar; 3323, first moving block; 333, second connecting structure; 3331, second U-shaped plate; 3332, second guide crossbar; 3333, second moving block; 3334, mounting plate; 334, synchronous drive structure; 3341, connecting block; 3342, first screw; 4, automatic cleaning mechanism; 41, high-pressure water pipe; 411 , nozzle; 412, strip sealing block; 42, first installation chamber; 43, second installation chamber; 44, first opening and closing mechanism; 441, fixing column; 442, driving plate; 443, driving arm assembly; 4431, first driving arm; 4432, second driving arm; 4433, limiting sleeve; 444, second linear drive; 45, second opening and closing mechanism; 46, rotating mechanism; 461, driven wheel; 462, synchronous transmission belt; 463, tensioning structure; 464, third driving structure; 4641, driving wheel; 4642, second rotation driver; 465, synchronous moving structure; 4651, first rectangular frame; 4652, third guide cross bar; 4653, third moving block; 4654, connecting plate; 4655, connecting column; 47, fixing mechanism; 471, clamping plate; 472, fourth driving structure; 4721, second rectangular frame; 4722, second screw; 4723, fourth guide cross bar; 4724, fourth moving block; 4725, third rotation driver. DETAILED DESCRIPTION

[0033] In order to further understand the features, technical means, specific objectives and functions of the present invention, the present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0034] Reference Figures 1 to 13 As shown: an enzymolysis furnace for preparing polypeptides that can be automatically cleaned, comprising an enzymolysis furnace body 1, a stirring structure 2, a driving mechanism 3 and an automatic cleaning mechanism 4; the enzymolysis furnace body 1 comprises a tank body 11 and a cover body 12, a plurality of cleaning windows 111 are provided in a circular array on the tank body 11, and the plurality of cleaning windows 111 penetrate the side wall of the tank body 11, a material inlet is provided at the upper end of the tank body 11, a material outlet is provided at the lower end of the tank body 11, and the cover body 12 is covered at the upper end of the tank body 11; the stirring structure 2 is provided inside the tank body 11, and the stirring structure 2 comprises a stirring shaft 21 and a plurality of stirring blades 22, the axis of the stirring shaft 21 is colinear with the central axis of the tank body 11, one end of the stirring shaft 21 extends upward from the cover body 12, and one end of the stirring shaft 21 is coaxially provided with a driven gear 211, A plurality of stirring blades 22 are installed on the stirring shaft 21; a driving mechanism 3 is arranged at the upper end of the cover body 12, and the driving mechanism 3 is used to drive the stirring structure 2 to move, and the driving mechanism 3 drives the stirring shaft 21 to rotate by driving the driven gear 211; an automatic cleaning mechanism 4 is arranged on the outside of the tank body 11, and the automatic cleaning mechanism 4 includes a plurality of high-pressure water pipes 41, and the plurality of high-pressure water pipes 41 respectively correspond to the plurality of cleaning windows 111, and the high-pressure water pipe 41 includes a cleaning part and a water supply part, and the cleaning part is close to the cleaning window 111, and a plurality of nozzles 411 are provided on the cleaning part, and the plurality of nozzles 411 are all facing the inside of the tank body 11, and the plurality of nozzles 411 are arranged along the busbar of the high-pressure water pipe 41, and the water supply part is located at the lower end of the cleaning part, and the water supply part is externally connected to a pressurized water supply device.

[0035] The raw materials for preparing the polypeptide are put into the tank body 11 from the feed inlet, and the driving mechanism 3 drives the stirring structure 2 to move. The stirring structure 2 stirs the raw materials evenly. After the polypeptide is prepared, it is discharged from the discharge port. At this time, the enzymatically hydrolyzed substances are attached to the inner wall of the tank body 11 and the stirring blades 22. The external pressurized water supply device provides cleaning water to the high-pressure water pipe 41, and the high-pressure water is sprayed from the nozzle 411. The water flow can be sprayed to the middle of the tank body 11 under the action of the high pressure. At the same time, the driving mechanism 3 drives the stirring structure 2 to rotate, and the stirring blades 22 rotate. The inner wall of the tank body 11 rotates at a high speed, while the water flow is stationary relative to the inner wall of the tank body 11. The high-speed rotating stirring blades 22 collide with the water flow, and the water flow is hit by the stirring blades 22 and hits the inner wall of the tank body 11. The water flow hits the inner wall of the tank body 11 and bounces off it and contacts the stirring blades 22 again. This is repeated, so that the water flow has a greater impact force each time it contacts the inner wall of the tank body 11 and the stirring blades 22, thereby improving the cleaning effect of the cleaning water on the inner wall of the tank body 11, the stirring shaft 21 and the stirring blades 22.

[0036] Reference Figure 4 and Figure 5 As shown: the driving mechanism 3 includes a first driving structure 31 and a second driving structure 32; the first driving structure 31 is arranged on one side above the cover 12, and the first driving structure 31 is used to drive the stirring structure 2 to stir various raw materials in the tank body 11, and the first driving structure 31 includes a driving gear 311 and a first rotating driver 312, the driving gear 311 is meshed with the driven gear 211, and the first rotating driver 312 is used to drive the driving gear 311 to rotate; the second driving structure 32 is arranged on the other side above the cover 12, and the second driving structure 32 is used to drive the stirring structure 2 to clean the inner wall of the tank body 11, and the second driving structure 32 includes a transmission rack 321, a mounting block 322, a guide structure 323 and a first linear driver 32 4. The transmission rack 321 is meshed with the driven gear 211. The mounting block 322 is arranged at one side of the transmission rack 321, and the transmission rack 321 is installed on the mounting block 322. The guide structure 323 is arranged at one end of the mounting block 322. The guide structure 323 includes a guide rod 3231 and a first spring 3232. One end of the guide rod 3231 is inserted into the mounting block 322. The first spring 3232 is sleeved on the guide rod 3231. The two ends of the first spring 3232 are respectively abutted against the end of the mounting block 322 and the end of the guide rod 3231. The first linear driver 324 is arranged at the other end of the mounting block 322. The first linear driver 324 is used to drive the mounting block 322 to reciprocate along the guide rod 3231.

[0037] High-pressure water is sprayed from the nozzle 411 to the interior of the tank body 11, and the first rotary driver 312 drives the driving gear 311 to rotate. The driving gear 311 drives the stirring shaft 21 to rotate through the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to rotate. The surface of the stirring blade 22 facing the direction of its own rotation will continue to collide with the cleaning water, and the surface of the stirring blade 22 away from the direction of its own rotation is difficult to contact with the cleaning water, resulting in the surface of the stirring blade 22 away from the direction of its own rotation cannot be cleaned. By setting the second driving structure 32, the first linear driver 324 first drives the mounting block 322 to move from the guide rod 3231 The mounting block 322 moves from one end to the other end, and the transmission rack 321 moves from one end of the guide rod 3231 to the other end. The transmission rack 321 drives the stirring shaft 21 to rotate forward through the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to rotate forward. One side surface of the stirring blade 22 contacts with the cleaning water, and then the first linear drive 324 drives the mounting block 322 to return. The mounting block 322 drives the stirring shaft 21 to reverse through the transmission rack 321 and the driven gear 211, and the stirring shaft 21 drives the stirring blade 22 to reverse. The other side surface of the stirring blade 22 contacts with the cleaning water, thereby achieving the cleaning of the surfaces on both sides of the stirring blade 22.

[0038] Reference Figure 4 and Figure 6 As shown: the driving mechanism 3 also includes a switching structure 33, which is arranged between the first driving structure 31 and the second driving structure 32. The switching structure 33 includes a U-shaped frame 331, a first connecting structure 332, a second connecting structure 333 and a synchronous driving structure 334; the U-shaped frame 331 is arranged above the first driving structure 31 and the second driving structure 32, and the U-shaped frame 331 is connected to the cover body 12, and the U-shaped frame 331 is symmetrically provided with a first mounting groove and a second mounting groove; the first connecting structure 332 is arranged in the first mounting groove, and the first connecting structure 332 connects the first driving structure 31 and the second driving structure 31 to the first driving structure 31. The first driving structure 31 is connected to the U-shaped frame 331, the first connecting structure 332 includes a first U-shaped plate 3321, a first guide cross bar 3322 and a first moving block 3323, the first U-shaped plate 3321 is installed in the first installation groove, the two ends of the first guide cross bar 3322 are respectively connected to the two ends of the first U-shaped plate 3321, the first moving block 3323 is slidably arranged on the first guide cross bar 3322, and the first rotating driver 312 is installed on the first moving block 3323; the second connecting structure 333 is arranged in the second installation groove, and the second connecting structure 333 connects the second driving The movable structure 32 is connected to the U-shaped frame 331, and the second connecting structure 333 includes a second U-shaped plate 3331, a second guide cross bar 3332 and a second moving block 3333. The second U-shaped plate 3331 is installed in the second installation groove, and the two ends of the second guide cross bar 3332 are respectively connected to the two ends of the second U-shaped plate 3331, and the axis of the second guide cross bar 3332 is colinear with the axis of the first guide cross bar 3322. The second moving block 3333 is slidably arranged on the second guide cross bar 3332, and the middle part of the mounting plate 3334 is connected to the second moving block 3333. The first straight line The driver 324 is arranged at one end of the mounting plate 3334, and one end of the guide rod 3231 is fixedly connected to the other end of the mounting plate 3334; the synchronous drive structure 334 is arranged on one side of the U-shaped frame 331, and the synchronous drive structure 334 is used to drive the first drive structure 31 and the second drive structure 32 to move synchronously. The synchronous drive structure 334 includes two connecting blocks 3341 and a first screw rod 3342. The two connecting blocks 3341 are respectively connected to the first moving block 3323 and the second moving block 3333, and the first screw rod 3342 is transmission-connected to the two connecting blocks 3341.

[0039] When the first driving structure 31 is working, the driving gear 311 drives the driven gear 211 to rotate, and the driven gear 211 drives the transmission rack 321 to move. When the second driving structure 32 is working, the movement of the transmission rack 321 is transmitted to the driving gear 311 through the driven gear 211. Therefore, it is necessary to keep a certain distance between the first driving structure 31 and the second driving structure and the driven gear 211. By setting the switching structure 33, when the stirring blade 22 stirs the raw materials, the first screw 3342 rotates forward, and the two connecting blocks 3341 respectively drive the first moving block 3323 and the second moving block 3333 to move in one direction. The first moving block 3323 drives the first rotation driver 312 to move toward the driven gear 211, and the driving gear 311 is meshed with the driven gear 211, so that the stirring blade 22 rotates continuously in the reverse direction. When the self-cleaning mechanism is working, the first screw 3342 is reversed, and the first moving block 3323 and the second moving block 3333 move in opposite directions. The driving gear 311 is disengaged from the driven gear 211, and the transmission rack 321 is meshed with the driven gear 211, so that the stirring blade 22 swings back and forth, thereby avoiding the problem of mutual interference between the first driving structure 31 and the second driving structure 32, so that the stirring structure 2 has two working modes.

[0040] Reference Figure 3 , Figure 7 and Figure 8 As shown: the automatic cleaning mechanism 4 also includes a first mounting bin 42, a second mounting bin 43, a first opening and closing mechanism 44 and a rotating mechanism 46; the first mounting bin 42 is arranged at the bottom of the tank body 11; the second mounting bin 43 is arranged at the bottom of the first mounting bin 42; the first opening and closing mechanism 44 is arranged in the first mounting bin 42, and the first opening and closing mechanism 44 is used to drive a plurality of high-pressure water pipes 41 away from the cleaning window 111 or close to the cleaning window 111; the rotating mechanism 46 is arranged in the second mounting bin 43, and the rotating mechanism 46 is used to drive a plurality of high-pressure water pipes 41 to rotate so that the nozzles 411 of the high-pressure water pipes 41 are away from the inner side of the tank body 11.

[0041] The nozzle 411 of the high-pressure water pipe 41 is directed toward the interior of the tank body 11. When enzymatic hydrolysis is performed in the tank body 11, the raw material may enter the high-pressure water pipe 41 from the nozzle 411. By setting a first opening and closing mechanism 44 and a rotating mechanism 46, before injecting the raw material into the tank body 11, the first opening and closing mechanism 44 works to separate the plurality of high-pressure water pipes 41 from the tank body 11, and then the rotating mechanism 46 works to rotate the plurality of high-pressure water pipes 41 at the same time, and the nozzles 411 of the high-pressure water pipes 41 turn away from the tank body 11. Then the first opening and closing mechanism 44 works again to connect the plurality of high-pressure water pipes 41 to the tank body 11, so that the cleaning window 111 on the tank body 11 is blocked, thereby preventing the raw material from entering the high-pressure water pipe 41 from the nozzle 411.

[0042] Reference Figure 7 and Figure 8 As shown: a strip-shaped sealing block 412 is also provided on the high-pressure water pipe 41 , and the strip-shaped sealing block 412 is provided along the generatrix of the high-pressure water pipe 41 .

[0043] The side wall of the tank body 11 has a certain thickness. When the high-pressure water pipe 41 is pressed against the tank body 11, there is a certain distance between the inner wall surface of the tank body 11 and the outer surface of the high-pressure water pipe 41. Therefore, there is still a cavity at the cleaning window 111 of the tank body 11, and part of the prepared polypeptide may remain in the cavity. During cleaning, the first opening and closing mechanism 44 and the rotating mechanism 46 again direct the nozzle 411 on the high-pressure water pipe 41 toward the inside of the tank body 11. During this process, the prepared polypeptide in the cavity will flow to the outside of the tank body 11. By setting the strip sealing block 412, when the work of preparing the polypeptide is carried out, the strip sealing block 412 is attached to the cleaning window 111 to fill the cavity there, and at the same time, the inner wall surface of the tank body 11 is made into a complete ring, thereby avoiding interference with the stirring blade 22, thereby avoiding part of the prepared polypeptide from flowing to the outside of the tank body 11.

[0044] Reference Figure 8 and Fig. 9 As shown: the first opening and closing mechanism 44 includes a fixed column 441, a driving plate 442, a plurality of driving arm assemblies 443 and a second linear driver 444, the fixed column 441 is arranged at the bottom of the tank body 11, and the axis of the fixed column 441 is collinear with the central axis of the tank body 11; the driving plate 442 is connected to the fixed column 441 through a bearing, the axis of the driving plate 442 is collinear with the axis of the fixed column 441, and the driving plate 442 has a plurality of corners; a plurality of driving arm assemblies 443 are respectively arranged at a plurality of corners of the driving plate 442, and a plurality of driving arm assemblies 443 connect the driving plate 442 with the lower ends of a plurality of high-pressure water pipes 41, and the driving arm assemblies 44 The first driving arm 4431 comprises a first driving arm 4431, a second driving arm 4432 and a limiting sleeve 4433. One end of the first driving arm 4431 is axially connected to one end of the second driving arm 4432. The other end of the first driving arm 4431 is axially connected to an angle of the driving plate 442. The other end of the second driving arm 4432 is connected to the lower end of the high-pressure water pipe 41 through a bearing. The limiting sleeve 4433 is fixed to the lower end of the tank body 11. The first driving arm 4431 is slidably arranged inside the limiting sleeve 4433. The second linear driver 444 is arranged at one side of the driving plate 442. The second linear driver 444 is used to push the driving plate 442 to rotate around the axis of the fixing column 441.

[0045] When it is necessary to control the high-pressure water pipe 41 to move away from the tank body 11, the second linear driver 444 pushes the driving plate 442, the driving plate 442 rotates forward around the axis of the fixed column 441, the driving plate 442 pushes a number of first driving arms 4431 to move, and the first driving arms 4431 respectively push a number of second driving arms 4432 to move, and the second driving arms 4432 respectively push a number of high-pressure water pipes 41 away from the tank body 11. When it is necessary to control the high-pressure water pipe 41 to be close to the tank body 11, the second linear driver 444 pulls the driving plate 442 to reverse around the axis of the fixed column 441, the driving plate 442 drives a number of first driving arms 4431 to move, and the first driving arms 4431 respectively apply a force toward the central axis of the tank body 11 to the second driving arms 4432, thereby realizing the simultaneous control of the movement of a number of high-pressure water pipes 41.

[0046] Reference Figure 3 and Fig.10 As shown: the automatic cleaning mechanism 4 also includes a second opening and closing mechanism 45, which is arranged inside the cover body 12, and the structure of the second opening and closing mechanism 45 is the same as that of the first opening and closing mechanism 44, and the second opening and closing mechanism 45 is connected to the upper ends of several high-pressure water pipes 41.

[0047] The high-pressure water pipe 41 is relatively long, and the first opening and closing mechanism 44 pulls the lower end of the high-pressure water pipe 41 toward the central axis of the tank body 11. The force between the lower end of the high-pressure water pipe 41 and the tank body 11 is relatively large, while the force between the upper end of the high-pressure water pipe 41 and the tank body 11 is relatively small, which may cause a gap between the upper end of the high-pressure water pipe 41 and the cleaning window 111 of the tank body 11. By setting the second opening and closing mechanism 45, the second opening and closing mechanism 45 and the first opening and closing mechanism 44 keep synchronous movement, and the upper and lower ends of the high-pressure water pipe 41 are subjected to the same force, thereby avoiding the formation of a gap between the high-pressure water pipe 41 and the tank body 11.

[0048] Reference Figure 8 and Fig.11 As shown: the rotating mechanism 46 includes a plurality of driven wheels 461, a synchronous transmission belt 462, a tensioning structure 463 and a third driving structure 464; the plurality of driven wheels 461 correspond to a plurality of high-pressure water pipes 41 respectively, and the driven gear 211 is installed at the lower end of the high-pressure water pipe 41; the synchronous transmission belt 462 is connected to the plurality of driven wheels 461; the tensioning structure 463 is arranged in the middle of the plurality of driven wheels 461, and the tensioning structure 463 keeps the synchronous transmission belt 462 in a tensioned state; the third driving structure 464 is arranged in the second mounting bin 43, and the third driving structure 464 is used to drive a driven wheel 461 to rotate, and the third driving structure 464 includes a driving wheel 4641 and a second rotating driver 4642, the driving wheel 4641 is tangent to the driven wheel 461, and the second rotating driver 4642 is used to drive the driving wheel 4641 to rotate.

[0049] When several high-pressure water pipes 41 are away from the tank body 11, the distance between several driven wheels 461 increases, the tensioning structure 463 adjusts the circulation path of the synchronous transmission belt 462 to keep the tension of the synchronous transmission belt 462 unchanged, and the second rotation driver 4642 drives the driving wheel 4641 to rotate, the driving wheel 4641 drives a driven wheel 461 to rotate, the driven wheel 461 drives the synchronous transmission belt 462 to move synchronously, and the synchronous transmission belt 462 drives the remaining driven wheels 461 to rotate, and the several driven wheels 461 therefore rotate synchronously, and the several driven wheels 461 respectively drive several high-pressure water pipes 41 to rotate, thereby realizing simultaneous control of several high-pressure water pipes 41 to adjust their own postures.

[0050] Reference Figure 8 , Fig.11 and Fig.12 As shown: the rotating mechanism 46 also includes a synchronous moving structure 465, which connects the third driving structure 464 with the driving arm assembly 443. The synchronous moving structure 465 includes a first rectangular frame 4651, a third guide cross bar 4652, a third moving block 4653, a connecting plate 4654 and a connecting column 4655. The first rectangular frame 4651 is installed at the bottom of the first installation bin 42, and the two ends of the third guide cross bar 4652 are respectively connected to the two ends of the first rectangular frame 4651, and the direction of the axis of the third guide cross bar 4652 is parallel to the direction of movement of the first driving arm 4431. The third moving block 4653 is slidably set on the third guide cross bar 4652, the connecting plate 4654 connects the third moving block 4653 with the second rotation driver 4642, and the connecting column 4655 connects the second driving arm 4432 with the third moving block 4653.

[0051] Since the driven wheel 461 will move with the high-pressure water pipe 41, the third driving structure 464 also needs to move with the driven wheel 461 so that the power of the driving wheel 4641 can be transmitted to the driven wheel 461. Therefore, a synchronous moving structure 465 is set. When the second driving arm 4432 drives the high-pressure water pipe 41 to move, the second driving arm 4432 drives the third moving block 4653 to move along the third guide cross bar 4652 through the connecting column 4655. The third moving block 4653 drives the second rotation driver 4642 to move through the connecting plate 4654, so that the driving wheel 4641 and the driven wheel 461 keep moving synchronously, so that the driving wheel 4641 and the driven wheel 461 are always pressed against each other, so that the power of the driving wheel 4641 is transmitted to the driven wheel 461.

[0052] Reference Figure 8 and Fig.13As shown: the automatic cleaning mechanism 4 also includes a fixing mechanism 47, which is arranged at the bottom of the tank body 11, and the fixing mechanism 47 includes two clamping plates 471 and a fourth driving structure 472; the two clamping plates 471 are respectively arranged at the two ends of the driving plate 442; the fourth driving structure 472 is arranged between the two clamping plates 471, and the fourth driving structure 472 includes a second rectangular frame 4721, a second screw rod 4722, a fourth guide cross bar 4723, two fourth moving blocks 4724 and a third rotating driver 4725, and both ends of the second rectangular frame 4721 are connected to the tank body 11, two ends of the second screw 4722 are respectively connected to two ends of the second rectangular frame 4721, and the second screw 4722 is a double-headed screw, the fourth guide cross bar 4723 is arranged in parallel on one side of the second screw 4722, and two ends of the fourth guide cross bar 4723 are respectively connected to two ends of the second rectangular frame 4721, two fourth moving blocks 4724 are respectively arranged at two ends of the second screw 4722, and the two fourth moving blocks 4724 are respectively connected to the two clamping plates 471, and the third rotation driver 4725 is used to drive the second screw 4722 to rotate.

[0053] The stirring structure 2 will generate vibration during stirring and cleaning operations, and the vibration may cause the first opening and closing mechanism 44 to loosen, resulting in the high-pressure water pipe 41 being separated from the tank body 11. By setting the fixing mechanism 47, the third rotation driver 4725 drives the second screw 4722 to rotate, and the second screw 4722 drives the two fourth moving blocks 4724 to approach each other. The two fourth moving blocks 4724 respectively drive the two clamping plates 471 to approach each other, and the two clamping plates 471 respectively abut against the two opposite sides of the driving plate 442, so that the driving plate 442 cannot rotate, thereby preventing the high-pressure water pipe 41 from being separated from the tank body 11 under the influence of vibration.

[0054] The above embodiments only express one or several implementation modes of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for those of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the attached claims.

Claims

1. An enzymatic hydrolysis furnace for polypeptide preparation that can be automatically cleaned, characterized in that: It comprises an enzymatic hydrolysis furnace body (1), a stirring structure (2), a driving mechanism (3) and an automatic cleaning mechanism (4); The enzymatic hydrolysis furnace body (1) comprises a tank body (11) and a cover body (12); a plurality of cleaning windows (111) are provided in a circular array on the tank body (11); the plurality of cleaning windows (111) penetrate the side wall of the tank body (11); and the cover body (12) is provided on the upper end of the tank body (11); The stirring structure (2) is arranged inside the tank body (11); The driving mechanism (3) is arranged at the upper end of the cover body (12), and the driving mechanism (3) is used to drive the stirring structure (2) to move; The automatic cleaning mechanism (4) is arranged outside the tank body (11), and comprises a plurality of high-pressure water pipes (41), the plurality of high-pressure water pipes (41) respectively corresponding to the plurality of cleaning windows (111), the high-pressure water pipe (41) comprising a cleaning portion and a water supply portion, the cleaning portion being closely attached to the cleaning window (111), the cleaning portion being provided with a plurality of nozzles (411), the plurality of nozzles (411) all facing the inside of the tank body (11), and the plurality of nozzles (411) being arranged along a busbar of the high-pressure water pipe (41), the water supply portion being located at the lower end of the cleaning portion, and the water supply portion being externally connected to a pressurized water supply device.

2. The automatic cleaning enzymolysis furnace for polypeptide preparation according to claim 1, characterized in that: The driving mechanism (3) comprises a first driving structure (31) and a second driving structure (32); The first driving structure (31) is arranged on one side above the cover body (12), and the first driving structure (31) is used to drive the stirring structure (2) to stir various raw materials in the tank body (11); The second driving structure (32) is arranged on the other side above the cover body (12), and the second driving structure (32) is used to drive the stirring structure (2) to clean the inner wall of the tank body (11).

3. The automatic cleaning enzymolysis furnace for polypeptide preparation according to claim 2, characterized in that: The driving mechanism (3) further comprises a switching structure (33), the switching structure (33) being arranged between the first driving structure (31) and the second driving structure (32), the switching structure (33) comprising a U-shaped frame (331), a first connecting structure (332), a second connecting structure (333) and a synchronous driving structure (334); The U-shaped frame (331) is disposed above the first drive structure (31) and the second drive structure (32), and the U-shaped frame (331) is connected to the cover body (12). The U-shaped frame (331) is symmetrically provided with a first mounting groove and a second mounting groove; The first connection structure (332) is arranged in the first installation groove, and the first connection structure (332) connects the first driving structure (31) and the U-shaped frame (331); The second connection structure (333) is arranged in the second installation groove, and the second connection structure (333) connects the second driving structure (32) and the U-shaped frame (331); The synchronous driving structure (334) is arranged on one side of the U-shaped frame (331), and the synchronous driving structure (334) is used to drive the first driving structure (31) and the second driving structure (32) to move synchronously.

4. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 1, characterized in that: The automatic cleaning mechanism (4) further comprises a first installation chamber (42), a second installation chamber (43), a first opening and closing mechanism (44) and a rotating mechanism (46); The first installation bin (42) is arranged at the bottom of the tank body (11); The second installation bin (43) is arranged at the bottom of the first installation bin (42); The first opening and closing mechanism (44) is disposed in the first installation compartment (42), and the first opening and closing mechanism (44) is used to drive the plurality of high-pressure water pipes (41) away from the cleaning window (111) or to be close to the cleaning window (111); The rotating mechanism (46) is arranged in the second installation chamber (43), and the rotating mechanism (46) is used to drive the plurality of high-pressure water pipes (41) to rotate so that the nozzles (411) of the high-pressure water pipes (41) face away from the inner side of the tank body (11).

5. An automatically cleanable enzymolysis furnace for preparing polypeptides according to claim 1, characterized in that: A strip-shaped sealing block (412) is also provided on the high-pressure water pipe (41), and the strip-shaped sealing block (412) is provided along the busbar of the high-pressure water pipe (41).

6. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 4, characterized in that: The first opening and closing mechanism (44) comprises a fixing column (441), a driving plate (442), a plurality of driving arm assemblies (443) and a second linear drive (444). The fixing column (441) is arranged at the bottom of the tank body (11), and the axis of the fixing column (441) is colinear with the central axis of the tank body (11); The driving plate (442) is connected to the fixing column (441) via a bearing, the axis of the driving plate (442) is colinear with the axis of the fixing column (441), and the driving plate (442) has a plurality of corners; A plurality of driving arm assemblies (443) are respectively arranged at a plurality of corners of the driving plate (442), and the plurality of driving arm assemblies (443) connect the driving plate (442) and the lower ends of a plurality of high-pressure water pipes (41); The second linear driver (444) is arranged on one side of the driving plate (442), and the second linear driver (444) is used to drive the driving plate (442) to rotate around the axis of the fixing column (441).

7. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 4, characterized in that: The automatic cleaning mechanism (4) further comprises a second opening and closing mechanism (45), which is arranged inside the cover body (12), the structure of the second opening and closing mechanism (45) is the same as that of the first opening and closing mechanism (44), and the second opening and closing mechanism (45) is connected to the upper ends of a plurality of high-pressure water pipes (41).

8. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 4, characterized in that: The rotating mechanism (46) comprises a plurality of driven wheels (461), a synchronous transmission belt (462), a tensioning structure (463) and a third driving structure (464); A plurality of driven wheels (461) respectively correspond to a plurality of high-pressure water pipes (41), and a driven gear (211) is installed at the lower end of the high-pressure water pipe (41); A synchronous transmission belt (462) is connected to a plurality of driven wheels (461); A tensioning structure (463) is disposed in the middle of the plurality of driven wheels (461), and the tensioning structure (463) keeps the synchronous transmission belt (462) in a tensioned state; The third driving structure (464) is arranged in the second installation chamber (43), and the third driving structure (464) is used to drive a driven wheel (461) to rotate.

9. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 8, characterized in that: The rotating mechanism (46) further comprises a synchronous moving structure (465), wherein the synchronous moving structure (465) connects the third driving structure (464) and the driving arm assembly (443).

10. The automatically cleanable enzymolysis furnace for polypeptide preparation according to claim 7, characterized in that: The automatic cleaning mechanism (4) further comprises a fixing mechanism (47), wherein the fixing mechanism (47) is arranged at the bottom of the tank body (11), and the fixing mechanism (47) comprises two clamping plates (471) and a fourth driving structure (472); Two clamping plates (471) are respectively arranged at two ends of the driving plate (442); The fourth driving structure (472) is arranged between the two clamping plates (471).

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