Quantitative instrument for cardiovascular pharmacological experiment
By using a transparent dosing barrel and a motor-driven drug pushing mechanism in the quantitative instrument used for cardiovascular pharmacology experiments, combined with the scale line and clamping mechanism, the quantitative deviation problem during the configuration of the drug solution is solved, and the accurate quantification of the drug solution and The stability of the test tube improves the accuracy of the experiment and the effectiveness of the equipment.
Patent Information
- Application Number
- CN202411621708.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-14
- Publication Date
- 2024-12-27
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
When the existing quantitative instruments for cardiovascular pharmacology experiments are configured, the operator needs to manually control the droplets of the drug while observing the drug liquid in the test tube, which can easily lead to excessive or low droplets of the drug liquid, resulting in deviations in the quantification, affecting Accuracy of pharmacological experiments.
A quantitative instrument for cardiovascular pharmacology experiments was designed, using transparent dosing barrels and drug pushing mechanisms, and the moving position of the piston was determined through the scale marks, and combined with the motor-driven drug pushing and control components to achieve accurate quantitative distribution of the drug solution. , and fix the test tube through a clamping mechanism to ensure its stability.
It improves the accuracy of the dosage of the drug solution and the stability of the experiment, reduces the droplet deviation of the drug solution, and improves the success rate of the experiment and the effectiveness of the equipment.
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Figure CN119186671A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of quantitative instruments, and in particular to a quantitative instrument for cardiovascular pharmacology experiments. Background Art
[0002] A quantitative instrument for cardiovascular pharmacology experiments was developed against the background of the increasing importance of cardiovascular disease research and the rising incidence rate. With the trend of younger people suffering from cardiovascular and cerebrovascular diseases and the enhancement of public health awareness, the demand for cardiovascular pharmacology experiments is growing. This quantitative instrument is designed to improve the accuracy of experimental drug preparation, thereby increasing the success rate of experiments and providing strong support for the treatment and research of cardiovascular diseases. It not only helps researchers to deeply understand the mechanism of action of drugs on the cardiovascular system, but also provides reliable experimental tools for the development of new cardiovascular drugs. With the continuous advancement of technology, this quantitative instrument is gradually becoming intelligent, automated and precise to meet the higher needs of scientific research and clinical practice.
[0003] After searching, the Chinese patent number CN218590564U discloses a quantitative instrument for pharmacological experiments, including a placing table, a pillar, a medicine cartridge and a piston pressing assembly. The pillar is arranged on the side wall of the placing table, the side wall of the medicine cartridge is provided with a fixed column, the fixed column is arranged on the side wall of the pillar, a piston is arranged in the medicine cartridge, and the piston pressing assembly is arranged on the pillar; the piston pressing assembly includes a screw, a screw pair, an active bevel gear and a driven bevel gear, the side wall of the pillar is provided with a slideway, both ends of the screw are slidably arranged on the slideway, the screw pair is threadedly connected to the screw and slidably arranged on the slideway, the bottom end of the screw pair is provided with a connecting rod, the bottom end of the connecting rod is connected to the top wall of the piston, the top wall of the placing table is provided with a placing groove, the active bevel gear is rotatably arranged on the side wall of the slideway, the driven bevel gear is fixedly sleeved on the screw, and the active bevel gear and the driven bevel gear are meshed. Compared with the prior art, the Chinese patent number CN218590564U solves the problem that when operating the prior art equipment, the worker has to manually rotate the turntable while observing the content of the solution in the test tube at the same time. During this operation, it is impossible to ensure that the worker's line of sight can be level and directly look at the scale on the test tube, which is prone to deviation.
[0004] However, in actual use of the above device, when using the device to prepare the drug solution, the personnel need to observe the drug solution in the test tube while manually controlling the dripping of the drug solution, which can easily lead to more or less drug solution dripping during the operation, resulting in quantitative deviations and affecting the accuracy of the pharmacological experiment. Therefore, a quantifier for cardiovascular pharmacological experiments is proposed. Summary of the invention
[0005] The purpose of the present invention is to solve the problem in the prior art that when using a device to prepare a drug solution, a person needs to observe the drug solution in a test tube while manually controlling the dripping of the drug solution, which can easily lead to too much or too little dripping of the drug solution during the operation, resulting in quantitative deviations and affecting the accuracy of the pharmacological experiment. A quantitative instrument for cardiovascular pharmacology experiments is proposed to solve the problem.
[0006] In order to achieve the above object, the present invention adopts the following technical solutions:
[0007] A quantitative instrument for cardiovascular pharmacology experiments, comprising a medicine adding barrel, the medicine adding barrel is made of a transparent material, and a scale line is arranged at the front end of the medicine adding barrel, a medicine pushing mechanism is arranged at the upper part of the medicine adding barrel, the medicine pushing mechanism can drive a piston slidably connected inside the medicine adding barrel to move and push out the medicine liquid, a control mechanism is arranged inside the piston, and a medicine adding tube is fixedly connected to the upper part of the control mechanism;
[0008] The control mechanism can control the internal movable baffle to rotate and control the opening and closing of the piston. The upper part of the medicine pushing mechanism is fixedly connected to the test bench. The upper part of the test bench is provided with a clamping mechanism. The clamping mechanism drives the clamps provided on both sides to close inward and fix the test tube placed in the middle. The test tube is located directly below the medicine adding barrel.
[0009] The above technical solution further includes:
[0010] The medicine pushing mechanism comprises a medicine adding shell fixedly connected to the upper part of the test bench, a second motor is arranged on the upper part of the medicine adding shell, and a medicine pushing assembly is arranged at the output end of the second motor.
[0011] The medicine pushing assembly includes a screw rod arranged at the output end of the second motor, the screw rod is rotatably connected to the medicine adding shell, the screw rod is threadedly connected to a transmission plate, a piston is fixedly connected to the lower part of the transmission plate, and the piston is slidably connected to the medicine adding barrel.
[0012] The rear end of the transmission plate is rotatably connected to two rotating wheels, a limiting plate is arranged in the middle of the rotating wheels, and the limiting plate is fixedly connected to the medicine adding shell.
[0013] The control mechanism comprises a control housing fixedly connected to the inside of the piston, the upper part of the control housing is fixedly connected to a dosing tube, the dosing tube is made of soft material and can inject medicine into the dosing barrel by connecting a syringe.
[0014] A third motor is arranged inside the control housing, and a control component is arranged at an output end of the third motor, and the control component drives the movable baffle to rotate.
[0015] The control component includes a fifth gear arranged at the output end of the third motor, the fifth gear is meshingly connected with the sixth gear, five eccentric shafts are fixedly connected to the bottom of the sixth gear, the eccentric shaft is rotatably connected to a movable baffle on the side away from the sixth gear, and the bottom of the movable baffle is rotatably connected to a control housing.
[0016] The clamping mechanism comprises a clamping shell fixedly connected to the upper part of the test bench, a first motor is arranged on the upper part of the clamping shell, and a clamping assembly is arranged at the output end of the first motor.
[0017] The clamping assembly includes a first gear arranged at the output end of the first motor, the first gear is symmetrically meshed with a second gear and a third gear on both sides, the second gear is meshed with a fourth gear, the third gear and the fourth gear are meshed with a rack, and the rack is slidably connected to the clamping shell.
[0018] The front end of the rack is fixedly connected with a clamp, and the upper part of the clamp is provided with a plurality of rubber protrusions.
[0019] The present invention has the following beneficial effects:
[0020] 1. In the present invention, when quantitatively dispensing medicine, the precise amount of medicine required for configuration is first determined according to the experimental requirements, and then the piston is driven to move by the medicine pushing mechanism. The scale lines arranged on the outside of the medicine adding barrel can help personnel determine the moving position of the piston. By moving the piston to different scale lines, the medicine liquid introduced into the medicine adding barrel can be quantitatively measured. Personnel no longer need to observe the test tube scale for quantitative measurement, which effectively improves the quantitative accuracy. After the quantitative medicine liquid is introduced into the medicine adding barrel through the medicine adding tube, the control component in the control shell can be started, and the movable baffle is driven to rotate by the control component to close the piston, so that subsequent liquid addition can be carried out, which is convenient and quick, and improves the use effect of the device.
[0021] 2. In the present invention, before adding liquid, the test tube can be placed between the two clamps, and then the clamping mechanism can be started. The clamps on both sides can be driven to close inward through the clamping mechanism, so as to clamp and fix the test tube, effectively ensuring the stability of the test tube during the experiment. In addition, a number of rubber protrusions are provided on the surface of the clamp, and these protrusions can increase the friction between the clamp and the test tube, thereby further improving the stability. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 A schematic diagram of the structure of a quantitative instrument for cardiovascular pharmacology experiments proposed by the present invention;
[0023] Figure 2 It is a schematic diagram of the overall structure of the clamping mechanism in the present invention;
[0024] Figure 3 It is a schematic diagram of the internal structure of the clamping shell in the present invention;
[0025] Figure 4 It is a schematic diagram of the overall structure of the medicine pushing mechanism in the present invention;
[0026] Figure 5 This is a schematic diagram of the connection relationship of the dosing barrels in the present invention;
[0027] Figure 6 This is a schematic diagram of the internal structure of the medicine adding barrel in the present invention;
[0028] Figure 7 It is a schematic diagram of the overall structure of the control mechanism in the present invention;
[0029] Figure 8 It is a schematic diagram of the internal structure of the control housing in the present invention.
[0030] In the figure: 1. dosing barrel; 2. clamping shell; 3. test bench; 4. test tube; 5. dosing shell; 6. first motor; 7. fixture; 8. first gear; 9. second gear; 10. third gear; 11. fourth gear; 12. rack; 13. dosing tube; 14. second motor; 15. screw rod; 16. limit plate; 17. rotating wheel; 18. transmission plate; 19. piston; 20. control shell; 21. movable baffle; 22. third motor; 23. fifth gear; 24. sixth gear; 25. eccentric shaft. DETAILED DESCRIPTION
[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0032] Embodiment 1
[0033] like Figure 1-Figure 8 As shown, the quantitative instrument for cardiovascular pharmacology experiments proposed by the present invention includes a medicine adding barrel 1, the medicine adding barrel 1 is made of transparent material, and a scale line is set at the front end of the medicine adding barrel 1, and a medicine pushing mechanism is set on the upper part of the medicine adding barrel 1. The medicine pushing mechanism can drive a piston 19 slidably connected inside the medicine adding barrel 1 to move and push out the medicine liquid, and a control mechanism is set inside the piston 19, and a medicine adding tube 13 is fixedly connected to the upper part of the control mechanism;
[0034] The control mechanism can control the internal movable baffle 21 to rotate and control the opening and closing of the piston 19. The upper part of the drug pushing mechanism is fixedly connected to the test bench 3. The upper part of the test bench 3 is provided with a clamping mechanism. The clamping mechanism drives the clamps 7 provided on both sides to close and fix the test tube 4 placed in the middle. The test tube 4 is located directly below the drug adding barrel 1.
[0035] The medicine pushing mechanism includes a medicine adding shell 5 fixedly connected to the upper part of the test bench 3, a second motor 14 is arranged on the upper part of the medicine adding shell 5, a medicine pushing assembly is arranged at the output end of the second motor 14, and the medicine pushing assembly includes a screw rod 15 arranged at the output end of the second motor 14, the screw rod 15 is rotatably connected to the medicine adding shell 5, the screw rod 15 is threadedly connected to a transmission plate 18, a piston 19 is fixedly connected to the lower part of the transmission plate 18, the piston 19 is slidably connected to the medicine adding barrel 1, and the rear end of the transmission plate 18 is rotatably connected to two rotating wheels 17, a limit plate 16 is arranged at the middle position of the rotating wheel 17, and the limit plate 16 is fixedly connected to the medicine adding shell 5;
[0036] The control mechanism includes a control shell 20 fixedly connected to the inside of the piston 19, the upper part of the control shell 20 is fixedly connected to the dosing tube 13, the dosing tube 13 is made of soft material, and can be connected to the dosing barrel 1 to inject medicine, a third motor 22 is arranged inside the control shell 20, and a control component is arranged at the output end of the third motor 22, and the control component drives the movable baffle 21 to rotate, and the control component includes a fifth gear 23 arranged at the output end of the third motor 22, the fifth gear 23 is meshingly connected to the sixth gear 24, and five eccentric shafts 25 are fixedly connected to the bottom of the sixth gear 24, and the eccentric shaft 25 is rotatably connected to the movable baffle 21 on the side away from the sixth gear 24, and the bottom of the movable baffle 21 is rotatably connected to the control shell 20.
[0037] In this embodiment, when the experiment is quantitatively dispensing, the precise amount of medicine required for configuration is first determined according to the experimental requirements, and then the second motor 14 on the upper part of the medicine-adding shell 5 is started, and the screw rod 15 is driven to rotate by the second motor 14. The rotation of the screw rod 15 can drive the threaded transmission plate 18 to move, and during the movement of the transmission plate 18, the two rotating wheels 17 arranged at the rear end are synchronously rotated along the limit plate 16, which effectively ensures the stability of the transmission plate 18 during movement. The movement of the transmission plate 18 can drive the piston 19 to move inside the medicine-adding barrel 1, and the scale lines arranged on the outside of the medicine-adding barrel 1 can help personnel determine the position of the piston 19. By moving the piston 19 to different scale lines, the liquid medicine introduced into the medicine-adding barrel 1 can be quantified, and personnel no longer need to observe the scale of the test tube 4 for quantification, which effectively improves the quantitative accuracy;
[0038] After a quantitative amount of liquid medicine is introduced into the dosing barrel 1 through the dosing tube 13, the third motor 22 inside the control shell 20 is started, and the fifth gear 23 is driven to rotate by the third motor 22. The rotation of the fifth gear 23 can drive the meshing connected sixth gear 24 to rotate, and the rotation of the sixth gear 24 can drive the eccentric shaft 25 fixedly connected to the bottom to rotate. The rotation of the eccentric shaft 25 can drive the movable baffle 21 rotatably connected to the bottom to rotate and close inward, which can ensure that the liquid medicine will not leak out through the control shell 20 during subsequent liquid pushing. Finally, the liquid pushing mechanism drives the piston 19 to be pressed down, so that the liquid medicine inside the dosing barrel 1 can be pushed out and added to the test tube 4 at the bottom, completing the quantitative liquid adding, which is convenient and quick, and improves the use effect of the device.
[0039] Embodiment 2
[0040] like Figure 1-Figure 8 As shown, the clamping mechanism includes a clamping housing 2 fixedly connected to the upper part of the test bench 3, a first motor 6 is arranged on the upper part of the clamping housing 2, and a clamping assembly is arranged at the output end of the first motor 6;
[0041] The clamping assembly includes a first gear 8 arranged at the output end of the first motor 6, the first gear 8 is symmetrically meshed with a second gear 9 and a third gear 10 on both sides, the second gear 9 is meshed with a fourth gear 11, the third gear 10 and the fourth gear 11 are meshed with a rack 12, the rack 12 is slidably connected to the clamping shell 2, the front end of the rack 12 is fixedly connected to a clamp 7, and a plurality of rubber protrusions are arranged on the upper part of the clamp 7.
[0042] In this embodiment, before adding liquid, the test tube 4 can be placed between the two clamps 7, and then the first motor 6 can be started. The first motor 6 can drive the first gear 8 to rotate. The rotation of the first gear 8 can drive the second gear 9 and the third gear 10 meshing on both sides to rotate, and the rotation of the second gear 9 can drive the meshing fourth gear 11 to rotate. The rotation of the fourth gear 11 and the third gear 10 can drive the meshing rack 12 to move. The movement of the rack 12 can drive the clamp 7 fixed at the front end to close inward, thereby clamping and fixing the test tube 4, effectively ensuring the stability of the test tube 4 during the experiment, and a number of rubber protrusions are provided on the surface of the clamp 7, through which the friction between the clamp 7 and the test tube 4 can be increased, thereby further improving the stability.
[0043] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A quantitative instrument for cardiovascular pharmacology experiments, comprising a drug adding barrel (1), characterized in that: The medicine adding barrel (1) is made of a transparent material, and a scale line is arranged at the front end of the medicine adding barrel (1). A medicine pushing mechanism is arranged at the upper part of the medicine adding barrel (1), and the medicine pushing mechanism can drive a piston (19) slidably connected inside the medicine adding barrel (1) to move and push out the medicine liquid. A control mechanism is arranged inside the piston (19), and a medicine adding tube (13) is fixedly connected to the upper part of the control mechanism. The control mechanism can control the rotation of the movable baffle (21) arranged inside to control the opening and closing of the piston (19). The upper part of the medicine pushing mechanism is fixedly connected to a test bench (3). The upper part of the test bench (3) is provided with a clamping mechanism. The clamping mechanism drives the clamps (7) arranged on both sides to close inwards and fix the test tube (4) placed in the middle. The test tube (4) is located directly below the medicine adding barrel (1).
2. A quantitative instrument for cardiovascular pharmacology experiments according to claim 1, characterized in that: The medicine pushing mechanism is equipped with a medicine adding shell (5) fixedly connected to the upper part of the test bench (3), a second motor (14) is arranged on the upper part of the medicine adding shell (5), and a medicine pushing component is arranged at the output end of the second motor (14).
3. A quantitative instrument for cardiovascular pharmacology experiments according to claim 2, characterized in that: The medicine pushing assembly comprises a screw rod (15) arranged at the output end of the second motor (14), the screw rod (15) being rotatably connected to the medicine adding shell (5), the screw rod (15) being threadedly connected to a transmission plate (18), a piston (19) being fixedly connected to the lower part of the transmission plate (18), and the piston (19) being slidably connected to the medicine adding barrel (1).
4. A quantitative instrument for cardiovascular pharmacology experiments according to claim 3, characterized in that: The rear end of the transmission plate (18) is rotatably connected to two rotating wheels (17), a limiting plate (16) is arranged in the middle of the rotating wheels (17), and the limiting plate (16) is fixedly connected to the medicine adding shell (5).
5. A quantitative instrument for cardiovascular pharmacology experiments according to claim 1, characterized in that: The control mechanism comprises a control housing (20) fixedly connected to the inside of the piston (19); the upper part of the control housing (20) is fixedly connected to a dosing tube (13); the dosing tube (13) is made of a soft material and can be connected to a syringe to inject medicine into the dosing barrel (1).
6. A quantitative instrument for cardiovascular pharmacology experiments according to claim 5, characterized in that: A third motor (22) is arranged inside the control housing (20), and a control component is arranged at the output end of the third motor (22), and the control component drives the movable baffle (21) to rotate.
7. A quantitative instrument for cardiovascular pharmacology experiments according to claim 6, characterized in that: The control assembly comprises a fifth gear (23) arranged at the output end of a third motor (22); the fifth gear (23) is meshingly connected with a sixth gear (24); five eccentric shafts (25) are fixedly connected to the bottom of the sixth gear (24); a side of the eccentric shaft (25) away from the sixth gear (24) is rotatably connected to a movable baffle (21); and a bottom of the movable baffle (21) is rotatably connected to a control housing (20).
8. A quantitative instrument for cardiovascular pharmacology experiments according to claim 1, characterized in that: The clamping mechanism comprises a clamping shell (2) fixedly connected to the upper part of the test bench (3), a first motor (6) is arranged on the upper part of the clamping shell (2), and a clamping assembly is arranged at the output end of the first motor (6).
9. A quantitative instrument for cardiovascular pharmacology experiments according to claim 8, characterized in that: The clamping assembly comprises a first gear (8) arranged at the output end of a first motor (6), the first gear (8) being symmetrically meshed with a second gear (9) and a third gear (10) on both sides, the second gear (9) being meshed with a fourth gear (11), the third gear (10) and the fourth gear (11) being meshed with a rack (12), and the rack (12) being slidably connected to the clamping housing (2).
10. A quantitative instrument for cardiovascular pharmacology experiments according to claim 9, characterized in that: The front end of the rack (12) is fixedly connected to a clamp (7), and a plurality of rubber protrusions are arranged on the upper part of the clamp (7).
Citation Information
Patent Citations
Quantitative instrument for pharmacological experiment
CN218590564U
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CN118707128A
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CN211755101U
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