Traditional Chinese medicine composition for improving sleep

Abstract

The invention discloses a traditional Chinese medicine composition for improving sleep. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-30 parts of radix glehniae, 5-20 parts of radix scrophulariae, 6-30 parts of lily, 5-15 parts of radix ophiopogonis, 2-10 parts of schisandra chinensis, 5-30 parts of caulis bambusae in taeniam, 5-30 parts of astragalus membranaceus and 10-30 parts of salvia miltiorrhiza. The traditional Chinese medicine composition for improving sleep has the technical effects of improving the sleep quality of patients and improving the traditional Chinese medicine syndromes of insomnia patients.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a Chinese medicine composition for improving sleep. Background Art

[0002] Sleep is a common physiological phenomenon of human beings. It is a periodic and reversible resting phenomenon regulated by the sleep visual center. It is an important means for the human body to relieve fatigue and improve physical functions. Studies have shown that reasonable sleep is an important factor affecting health. Long-term lack of sleep and poor sleep quality can lead to mental problems such as anxiety and depression. In severe cases, it can affect various body functions. Sleep is also an important guarantee for the growth and development of the human body during childhood. During sleep, the body secretes various hormones that promote physical development, such as growth hormone and thyroid hormone, and the secretion reaches a peak during sleep at night. One-third of a person's life is spent in sleep. Sleep is a necessity of life. People cannot live without sleep. Sleep quality plays a vital role in human health.

[0003] Insomnia refers to a subjective experience in which patients are not satisfied with their sleep duration and / or quality, which affects their daytime social functions. According to the cause, it can be divided into primary and secondary types.

[0004] Primary insomnia usually lacks a clear cause, or insomnia symptoms remain after excluding possible causes of insomnia. It mainly includes three types: psychophysiological insomnia, idiopathic insomnia and subjective insomnia. The diagnosis of primary insomnia lacks specific indicators and is mainly an exclusion diagnosis. When possible causes of insomnia are excluded or cured, if insomnia symptoms still remain, it can be considered primary insomnia. Clinically, it is found that the causes of psychophysiological insomnia can be traced back to the impact of a certain or long-term event on the functional stability of the patient's brain limbic system. The imbalance of the stability of the limbic system function ultimately leads to the disorder of the brain's sleep function and insomnia occurs.

[0005] Secondary insomnia includes insomnia caused by physical illness, mental disorders, drug abuse, etc., as well as insomnia related to sleep-disordered breathing, sleep movement disorders, etc.

[0006] Insomnia often occurs with other diseases, and sometimes it is difficult to determine the causal relationship between these diseases and insomnia. Therefore, in recent years, the concept of comorbid insomnia has been proposed to describe insomnia that is accompanied by other diseases. Lack of sleep may lead to poor spirits, memory loss, low immunity, endocrine disorders, skin abnormalities and other hazards.

[0007] Currently, most sleeping aids on the market are Western medicines, while traditional Chinese medicine has unique advantages in improving insomnia through multiple pathways and fewer side effects; however, the types of Chinese patent medicine preparations are still relatively small, and the efficacy is not very significant. Summary of the invention

[0008] In order to solve the above technical problems, the present invention provides a Chinese medicine composition for improving sleep, which has the technical effects of improving the sleep quality of patients and improving the TCM symptoms of insomnia patients.

[0009] In order to achieve the above object, the present invention adopts the following technical solutions: The present invention provides a Chinese medicine composition for improving sleep, which is prepared from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-30 parts of Rhizoma Anemarrhenae, 5-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0010] Further, it is prepared from the following Chinese medicine raw materials in parts by weight: 10-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 10-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 3-10 parts of Schisandra chinensis, 10-30 parts of Rhizoma Anemarrhenae, 5-20 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0011] Further, it is prepared from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-10 parts of Rhizoma Anemarrhenae, 15-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0012] In summary, the beneficial effects of the present invention are: The Chinese medicine composition for improving sleep of the present invention comprises Radix Adenophorae, Radix Scrophulariae, Lilium, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Rhizoma Anemarrhenae, Radix Astragali and Radix Salviae Miltiorrhizae. Radix Adenophorae has the effects of nourishing yin and clearing lung, removing phlegm and relieving cough, etc.; Radix Scrophulariae has the effects of clearing heat and cooling blood, nourishing yin and reducing fire, detoxifying and dispersing knots, etc.; Lilium has the effects of nourishing yin and moistening lung, clearing heart and calming nerves, etc.; Radix Ophiopogonis has the effects of nourishing yin and promoting body fluid, moistening lung and clearing heart, etc.; Fructus Schisandrae Chinensis has the effects of astringing and consolidating, invigorating qi and promoting body fluid, nourishing kidney and calming heart, etc.; Rhizoma Anemarrhenae has the effects of clearing heat and resolving phlegm, eliminating restlessness, and stopping vomiting, etc.; Radix Astragali has the effects of strengthening spleen and replenishing middle, raising yang and lifting depression, invigorating defense and strengthening exterior, diuresis, supporting poison and promoting muscle regeneration, etc.; Radix Salviae Miltiorrhizae has the effects of removing blood stasis and relieving pain, promoting blood circulation and dredge menstruation, clearing heart and removing restlessness, etc. The Chinese medicine composition for improving sleep of the present invention is completely consistent with the pathogenesis of insomnia, has been verified by clinical trials, has significant clinical efficacy, and is used to improve sleep and improve sleep quality.

[0013] It should be noted that Adenophora scabra, Lilium bulbifera, Scrophularia ningpoensis, soothing the liver, nourishing the heart and lungs, nourishing the heart and calming the mind are the main drugs, Schisandra chinensis, Ophiopogon japonicus replenish qi and nourish yin to assist the main drugs to calm the mind. Salvia miltiorrhiza and Rhizoma Anemarrhenae nourish the heart, activate blood circulation, cool blood, relieve restlessness and calm the mind, and make the drugs enter the heart meridian, which are the adjuvant drugs, and Astragalus membranaceus replenishes qi and strengthens the spleen, so that all the drugs can work together to achieve the effect of calming the mind. DETAILED DESCRIPTION

[0014] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0015] The present invention provides a Chinese medicine composition for improving sleep, which is prepared from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-30 parts of Rhizoma Anemarrhenae, 5-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0016] Among them, it can also be made from the following Chinese medicine raw materials in parts by weight: 10-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 10-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 3-10 parts of Schisandra chinensis, 10-30 parts of Rhizoma Anemarrhenae, 5-20 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0017] Among them, it can also be made from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-10 parts of Rhizoma Anemarrhenae, 15-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

[0018] Among them, the above weight ratio is obtained through scientific screening. For special patients, such as severe or mild, obese or thin patients, the amount ratio of the composition can be adjusted accordingly, and the increase or decrease does not exceed 100%, and the efficacy remains basically unchanged. The Chinese medicine composition for improving sleep of the present invention, if in g, is usually used for one dose, and greasy, raw, cold, fishy, ​​irritating and indigestible food is forbidden during the treatment period.

[0019] In the Chinese medicine composition for improving sleep of the present invention: Radix Adenophorae: Nature and flavor: sweet, bitter, light, cool. Enters the lung and spleen meridians. Functions and indications: nourishing yin and clearing the lungs, removing phlegm and relieving cough. Treats lung heat and dry cough, chronic cough due to consumptive tuberculosis, dry throat and thirst due to yin injury. "New Compendium of Materia Medica": Specially nourishes lung yin, clears lung fire, treats chronic cough and pulmonary tuberculosis. "New Reference for Decoction Pieces": nourishes lung and stomach yin, treats cough due to fatigue and sputum and blood. "Zhongyao Zhi": nourishes lung yin, clears lung heat, removes phlegm and relieves cough. Treats fever due to consumptive tuberculosis, dry cough due to yin injury, thirst and dry throat.

[0020] Scrophularia: Nature and flavor: sweet, bitter, salty, slightly cold. Enters the spleen, stomach, and kidney meridians. Functions and indications: clearing heat and cooling blood; nourishing yin and reducing fire; detoxifying and dispersing stagnation. "Medical Origin": "It can treat heart annoyance and insomnia, mental confusion, blood stasis and urinary incontinence." "Yao Xing Lun": "It can treat sudden heat, hot wind headache, typhoid fever, fatigue, and tumors. "Rihuazi Materia Medica": "It can treat head wind, heat toxicity, wandering wind, replenishing deficiency and fatigue, heart palpitations and irritability, lack of bone steaming, corpse evil spirits, stop forgetfulness, and reduce swelling and poison." Lily: Nature and flavor: sweet, cold. Enters the heart and lung meridians. Functions and indications: nourishing yin and moistening the lungs, clearing the heart and calming the mind. "Compendium of Materia Medica": "The function of lily is to replenish qi and benefit qi, to nourish the body and remove evil, so Li Zhen called it a good medicine for penetrating, benefiting and harmonizing the middle. For example, in the case of typhoid fever with lily, "Essentials" says that the patient cannot stand still when walking, sitting or lying down, as if there is a spirit. This shows that the evil and the body are intertwined and in chaos in the chest, and the meaning of using this flavor as the main treatment is worth thinking about." "Medical Collection": "Lily is used for astringency, and is suitable for those with internal deficiency, deficiency heat, deficiency cough, and deficiency swelling. It is the opposite of the function of ginger." Ophiopogon japonicus: Nature and flavor: sweet, slightly bitter, slightly cold. It enters the heart, lung, and stomach meridians. Functions and indications: nourishing yin and producing body fluid, moistening the lungs and clearing the heart. Used for dry cough due to lung dryness. Consumption cough, thirst due to loss of body fluid, restlessness and insomnia, internal heat and thirst, dry intestines and constipation; diphtheria. "Ben Jing": "It is used to treat qi stagnation in the heart and abdomen, injury to the middle and fullness, severance of stomach collaterals, emaciation and shortness of breath." "Bie Lu": "It is used to treat heaviness of the body and yellow eyes, fullness under the heart, asthenia and guest heat, dry mouth and thirst, stop vomiting, cure paralysis, strengthen yin and benefit essence, digest food and regulate the middle, protect the mind, stabilize lung qi, calm the five internal organs, and make people fat and healthy." "Yao Xing Lun": "It is used to treat heat toxicity, stop thirst, and treat edema of the face, eyes and limbs caused by large water, and to treat water discharge. It is used to treat pulmonary tuberculosis and vomiting of pus, and to treat spermatorrhea." "Ben Cao Shi Yi": "It is used to treat cold and heat body fatigue, and to treat phlegm and fluid." "Yao Yu Xin Fa": "It is used to replenish insufficient heart qi and treat blood circulation." Schisandra chinensis: Nature and flavor: sour, sweet, warm. Enters the lung, heart, and kidney meridians. Functions and indications: astringent, invigorating qi and generating body fluid, tonifying the kidney and calming the mind. Used for chronic cough, weak asthma, nocturnal emission, frequent urination, chronic diarrhea, spontaneous sweating, night sweats, thirst due to loss of body fluid, internal heat and thirst, palpitations and insomnia. "Compendium of Materia Medica" nourishes the five internal organs, removes heat, and generates yin and muscles. Schisandra chinensis is specialized in tonifying the kidney and the five internal organs. The kidney stores essence. When the essence is abundant, the yin is strong. When it is collected, the true qi returns to the origin. The dantian is warm, the water and grain are rotten, the dregs are steamed and transformed into essence, then the essence is produced naturally, and when the essence is produced, the yin grows, so it is used for the above diseases. "Annotation to Treatise on Febrile Diseases": "Huangdi Neijing" says that if the lungs want to be contracted, eat sour food to contract them. The sourness of peony and Schisandra chinensis can be used to contract the adverse qi and calm the lungs.

[0021] Bamboo Shavings: Nature and flavor: sweet, slightly cold. Enters the lung, stomach, heart, and gallbladder meridians. Functions and indications: clearing away heat and resolving phlegm, eliminating restlessness, and stopping vomiting. Used for phlegm-heat cough, gallbladder fire with phlegm, palpitations, restlessness, insomnia, stroke with phlegm, stiff tongue and speechlessness, stomach heat vomiting, nausea during pregnancy, and restless fetuses. "Compendium of Materia Medica": Treats typhoid fever, fever epilepsy in children, and fetal movements in women. "Compendium of Materia Medica": Treats pulmonary tuberculosis with spitting phlegm, hematuria, blood-heat metrorrhagia in women, fetal movements, and wind-heat epilepsy in children, phlegm, asthma, cough, and hot and astringent urination. "Bielu": Treats vomiting, warming qi, cold and heat, vomiting blood, metrorrhagia, and tendon overflow.

[0022] Astragalus: Nature and flavor: sweet, slightly warm; enters the spleen and lung meridians; Functions and indications: invigorates the spleen and replenishes the middle, raises yang and lifts the sunken, benefits the defense and consolidates the exterior, promotes urination, removes toxins and promotes muscle regeneration; mainly treats spleen qi deficiency syndrome, lung qi deficiency syndrome, qi deficiency and spontaneous sweating syndrome, qi and blood deficiency, sores that are difficult to ulcerate and decay, or sores that are difficult to heal for a long time. "Shennong's Herbal Classic": sweet, slightly warm. Mainly used for carbuncle, long-term wound, pus discharge, pain relief, leprosy, five hemorrhoids, rat fistula, tonifying deficiency, and all kinds of diseases in children. "Famous Doctors' Records": replenishes the deficiency of men, five kinds of labor and emaciation. Quenches thirst, abdominal pain, diarrhea, replenishes qi, and benefits yin qi.

[0023] Danshen: Nature and flavor: bitter, slightly cold. Enters the heart and liver meridians. Functions and indications: removes blood stasis and relieves pain, promotes blood circulation and dredges the menstruation, clears the heart and relieves restlessness. Used for irregular menstruation, amenorrhea, dysmenorrhea, accumulation of lumps, stabbing pain in the chest and abdomen, pain caused by heat arthralgia, swelling and pain in sores, restlessness and insomnia; hepatosplenomegaly, angina pectoris. "Ben Jing": "It treats evil qi in the heart and abdomen, rumbling in the intestines like running water, and accumulation of cold and heat; it can break up symptoms and remove masses, stop restlessness and fullness, and replenish qi." "Wu Pu's Materia Medica": "It treats heart and abdominal pain." "Bie Lu": "It nourishes blood, removes chronic diseases and qi in the heart and abdomen, strengthens the waist and spine, and relieves leg numbness; it removes wind evil and retained heat, and long-term use is beneficial to people." "Diannan Materia Medica": "It nourishes the heart and calms the mind, calms the mind and calms the heart. It treats forgetfulness, palpitations and insomnia." "Compendium of Materia Medica": "It promotes blood circulation and clears the pericardium. It treats hernia pain." "Yunnan Chinese Herbal Medicine Selection": "It promotes blood circulation and disperses blood stasis, calms and relieves pain. It treats irregular menstruation, dysmenorrhea, rheumatic pain, uterine bleeding, vomiting blood, mastitis, and carbuncle." Example

[0024] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-30 parts of Rhizoma Anemarrhenae, 5-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza. Example

[0025] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 10-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 10-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 3-10 parts of Schisandra chinensis, 10-30 parts of Rhizoma Anemarrhenae, 5-20 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza. Example

[0026] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-10 parts of Rhizoma Anemarrhenae, 15-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza. Example

[0027] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 5 parts of Adenophora adenophora, 5 parts of Scrophularia ningpoensis, 6 parts of Lilium, 5 parts of Ophiopogon japonicus, 2 parts of Schisandra chinensis, 5 parts of Rhizoma Anemarrhenae, 5 parts of Astragalus, and 10 parts of Salvia miltiorrhiza. Example

[0028] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 30 parts of Adenophora adenophora, 20 parts of Scrophularia ningpoensis, 30 parts of Lilium, 15 parts of Ophiopogon japonicus, 10 parts of Schisandra chinensis, 10 parts of Rhizoma Anemarrhenae, 30 parts of Astragalus, and 30 parts of Salvia miltiorrhiza. Example

[0029] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 15 parts of Adenophora adenophora, 15 parts of Scrophularia ningpoensis, 15 parts of Lilium, 10 parts of Ophiopogon japonicus, 8 parts of Schisandra chinensis, 8 parts of Rhizoma Anemarrhenae, 20 parts of Astragalus, and 15 parts of Salvia miltiorrhiza. Example

[0030] Provided is a Chinese medicine composition for improving sleep, wherein the weight proportions of the raw materials are as follows: 20 parts of Adenophora adenophora, 17 parts of Scrophularia ningpoensis, 20 parts of Lilium, 12 parts of Ophiopogon japonicus, 7 parts of Schisandra chinensis, 22 parts of Rhizoma Anemarrhenae, 20 parts of Astragalus, and 25 parts of Salvia miltiorrhiza.

[0031] The inventors conducted a clinical pharmacodynamics test on the Chinese medicine of Example 1, the details are as follows: Study subjects 150 patients with insomnia were selected. Inclusion criteria: (1) The diagnosis of insomnia complies with the relevant diagnostic criteria in Diagnostics; the TCM diagnosis of insomnia complies with the relevant diagnostic criteria for "insomnia" in the Guiding Principles for Clinical Research of New Chinese Medicines: symptoms: frequent dreams, easy awakening, restlessness, palpitations, chest tightness, loss of appetite, dry mouth and bitter taste, stomach discomfort, fever in the five parts, forgetfulness, pale complexion, insufficient qi and blood, yin deficiency and hyperactivity of fire, liver fire disturbing the heart, etc.; (2) 30 years old < age < 80 years old; (3) voluntary participation in this study and signing of the informed consent form.

[0032] Exclusion criteria: (1) patients with severe liver and kidney dysfunction, blood system and malignant tumors; (2) pregnant or lactating women; (3) patients with poor compliance due to mental illness and unable to cooperate with treatment and observation.

[0033] Treatment The Chinese medicine composition for improving sleep of the present invention has the functions of soothing the liver and strengthening the spleen, clearing away heat and reducing fire, nourishing kidney yin, and calming the mind; the formula is as follows: 20g of Adenophora australis, 15g of Scrophularia ningpoensis, 30g of Salvia miltiorrhiza, 30g of Lilium, 15g of Ophiopogon japonicus, 10g of Schisandra chinensis, 30g of Rhizoma Anemarrhenae, and 20g of Astragalus membranaceus; decoction is taken in water, one dose per day, divided into morning and evening. A course of treatment is 2 months.

[0034] Efficacy indicators Sleep duration and sleep quality: The sleep duration was recorded before and after treatment, and the sleep quality was scored (out of 100).

[0035] TCM symptom scores: frequent dreams, easy awakening, restlessness, palpitations, chest tightness, loss of appetite, dry and bitter mouth, stomach discomfort, fever in the five parts of the body, forgetfulness, pale complexion, insufficient qi and blood, yin deficiency and hyperactivity of fire, liver fire disturbing the heart, etc., from mild to severe, 1, 2, and 3 points respectively.

[0036] Safety indicators: routine blood tests, urine tests, and liver and kidney function tests were performed before and after treatment, and adverse events were recorded.

[0037] Efficacy evaluation criteria Refer to the evaluation criteria for the efficacy of TCM symptoms of insomnia in the "Guidelines for Clinical Research of New Chinese Medicines": Safety indicators: routine blood tests, urine tests, and liver and kidney function tests were performed before and after treatment, and adverse events were recorded.

[0038] Refer to the evaluation criteria for the efficacy of TCM symptoms of insomnia in the "Guidelines for Clinical Research of New Chinese Medicines"; Cure: After treatment, clinical symptoms and signs were significantly improved, and the TCM symptom score improved by >90% compared with before treatment.

[0039] Markedly effective: Clinical symptoms and signs were significantly improved after treatment, and the TCM symptom score improved by >70% compared with before treatment.

[0040] Effective: After treatment, the clinical signs improved and the TCM symptom score improved by 30% to 70% compared with the treatment.

[0041] Ineffective: After treatment, the clinical signs did not improve or even worsened, and the TCM symptom score improved by <30% compared with the treatment.

[0042] Cure rate %=number of cured cases / total number of cases x 100%; total effective rate %=(number of cured + markedly effective + effective) cases / total number of cases x 100%.

[0043] result Sleep improvement After treatment, the patients' sleep duration (hours) and sleep quality (percentage system) were significantly lower than those before treatment, and the difference was statistically significant (P<0.05), as shown in Table 1. Table 1. Comparison of sleep before and after treatment time Sleep duration Sleep quality Before treatment 3 55 After treatment 5.6 76 TCM symptom efficacy Among 150 patients with insomnia, 128 were cured, 15 were significantly effective, 7 were effective, and 0 were ineffective. The cure rate was 85%, and the total effective rate was 100.0%.

[0044] Improvement in quality of life After treatment, the patient's quality of life scores were significantly improved compared with those before treatment, and the difference was statistically significant (P<0.05). See Table 2 for details. Table 2. Comparison of quality of life scores between the two groups time G F1.4-F22.1 F2.1-F9.1 F3.3-F23.3 26 101-104 Before treatment 3±1.8 10.6±4.5 11±5.6 18±2.8 2.9±1.3 4.7±3.5 After treatment 5±2.5 20±5.2 18±6.7 30±4.1 3.2±0.5 9±2.4 The Chinese medicine composition for improving sleep of the present invention comprises Radix Adenophorae, Radix Scrophulariae, Lilium, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Rhizoma Anemarrhenae, Radix Astragali and Radix Salviae Miltiorrhizae. Radix Adenophorae has the effects of nourishing yin and clearing lung, removing phlegm and relieving cough, etc.; Radix Scrophulariae has the effects of clearing heat and cooling blood, nourishing yin and reducing fire, detoxifying and dispersing knots, etc.; Lilium has the effects of nourishing yin and moistening lung, clearing heart and calming nerves, etc.; Radix Ophiopogonis has the effects of nourishing yin and promoting body fluid, moistening lung and clearing heart, etc.; Fructus Schisandrae Chinensis has the effects of astringing and consolidating, invigorating qi and promoting body fluid, nourishing kidney and calming heart, etc.; Rhizoma Anemarrhenae has the effects of clearing heat and resolving phlegm, eliminating restlessness, and stopping vomiting, etc.; Radix Astragali has the effects of strengthening spleen and replenishing middle, raising yang and lifting depression, invigorating defense and strengthening exterior, diuresis, supporting poison and promoting muscle regeneration, etc.; Radix Salviae Miltiorrhizae has the effects of removing blood stasis and relieving pain, promoting blood circulation and dredge menstruation, clearing heart and removing restlessness, etc. The Chinese medicine composition for improving sleep of the present invention is completely consistent with the pathogenesis of insomnia, has been verified by clinical trials, has significant clinical efficacy, and is used to improve sleep and improve sleep quality.

[0045] It should be noted that Adenophora scabra, Lilium bulbifera, Scrophularia ningpoensis, soothing the liver, nourishing the heart and lungs, nourishing the heart and calming the mind are the main drugs, Schisandra chinensis, Ophiopogon japonicus replenish qi and nourish yin to assist the main drugs to calm the mind. Salvia miltiorrhiza and Rhizoma Anemarrhenae nourish the heart, activate blood circulation, cool blood, relieve restlessness and calm the mind, and make the drugs enter the heart meridian, which are the adjuvant drugs, and Astragalus membranaceus replenishes qi and strengthens the spleen, so that all the drugs can work together to achieve the effect of calming the mind.

[0046] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. A Chinese medicine composition for improving sleep, characterized in that: Made from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-30 parts of Rhizoma Anemarrhenae, 5-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

2. The Chinese medicine composition for improving sleep according to claim 1, characterized in that: Made from the following Chinese medicine raw materials in parts by weight: 10-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 10-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 3-10 parts of Schisandra chinensis, 10-30 parts of Rhizoma Anemarrhenae, 5-20 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.

3. The Chinese medicine composition for improving sleep according to claim 2, characterized in that: Made from the following Chinese medicine raw materials in parts by weight: 5-30 parts of Adenophora adenophora, 5-20 parts of Scrophularia ningpoensis, 6-30 parts of Lilium, 5-15 parts of Ophiopogon japonicus, 2-10 parts of Schisandra chinensis, 5-10 parts of Rhizoma Anemarrhenae, 15-30 parts of Astragalus, and 10-30 parts of Salvia miltiorrhiza.