Stirring and mixing device for high-viscosity medicinal preparation

Abstract

The invention discloses a stirring and mixing device for a high-viscosity medicinal preparation, and belongs to the technical field of medicinal preparation production.The stirring and mixing device comprises a base, and by arranging a driving unit, the position of a stirring straight plate can be changed in the process that the stirring straight plate stirs raw materials, so that the mixing effect of the raw materials is improved; a stirring straight plate corresponding to a first lifting sliding plate can be moved to the position where the axis of the mixing cylinder is located, and therefore the situation that raw materials in the center area of the mixing cylinder cannot be stirred and mixed is prevented; the first lifting sliding plate and the second lifting sliding plate move up and down in the mixing cylinder, so that the mixing effect of the raw materials is further improved, homogeneous mixing of the raw materials can be achieved through mutual cooperation of the stirring assembly, the cleaning assembly and the covering assembly, the mixing effect of the raw materials is improved, and then the quality of the prepared high-viscosity pharmaceutical preparation is improved.

Description

Technical Field

[0001] The invention relates to the technical field of pharmaceutical preparation production, in particular to a stirring and mixing device for high-viscosity pharmaceutical preparations. Background Art

[0002] Due to their physical properties, high-viscosity drug preparations need to ensure that drug raw materials, additives and excipients are fully and evenly mixed under high viscosity conditions, and even mixing is crucial to improving the quality and stability of drug preparations. However, traditional stirring methods achieve even mixing. Therefore, a special stirring and mixing device is used to help avoid stratification or agglomeration during the production process, thereby ensuring the consistency and effectiveness of the drug. However, existing stirring and mixing devices have poor mixing effects, cannot ensure sufficient mixing of raw materials, and are not convenient for taking out the mixed high-viscosity drug preparations. Therefore, the present invention provides a stirring and mixing device for high-viscosity drug preparations. Summary of the invention

[0003] The present invention aims at the defects of the prior art and provides a stirring and mixing device for high-viscosity drug preparations, which overcomes the problems of poor mixing effect, inability to ensure sufficient mixing of raw materials, and inconvenience in taking out and cleaning the mixed high-viscosity drug preparations.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a stirring and mixing device for high-viscosity drug preparations, comprising a base, a transposition ring frame movably arranged on the base, a mixing cylinder rotatably mounted on the transposition ring frame, a stirring assembly and a cleaning assembly arranged on the mixing cylinder, the stirring assembly comprising a lifting slide plate 1 and two lifting slide plates 2, three arc-shaped long plates slidably mounted in a circular array on the mixing cylinder, the lifting slide plate 1 and the two lifting slide plates 2 are respectively slidably mounted on the corresponding arc-shaped long plates, the ends of the lifting slide plate 1 and the lifting slide plate 2 closest to the axis of the mixing cylinder are both slidably mounted with stirring straight plates, a driving unit is arranged between the lifting slide plate 1 and the two lifting slide plates 2, the driving unit is used to make the displacement of the lifting slide plate 1 twice the displacement of the lifting slide plate 2, the cleaning assembly comprises a circular scraper, the circular scraper is used to scrape and clean the attachments on the stirring straight plate and the inner wall of the mixing cylinder, the transposition ring frame is also provided with a covering assembly, the covering assembly comprises an auxiliary slide, semicircular cover plates are symmetrically and movably arranged on the auxiliary slide, and the two semicircular cover plates are used to cover the ends of the mixing cylinder.

[0005] Furthermore, a transposition circular plate is fixedly arranged on the side of the transposition ring frame, and the transposition circular plate is rotatably mounted on the base. The arc surface of the arc-shaped long plate closest to the axis of the mixing cylinder and the circumferential surface inside the mixing cylinder are on the same circumferential surface, and there is no gap between the two sides of the semicircular cover plate and the mixing cylinder.

[0006] Furthermore, the driving unit includes a positioning gear 1 and two positioning gears 2, which are respectively rotatably mounted on the corresponding arc-shaped long plates, a positioning rack 1 is fixedly mounted on the side of the lifting slide 1, and a positioning rack 2 is fixedly mounted on the side of the lifting slide 2, the positioning rack 1 is meshed with the positioning gear 1 to form a gear rack pair, and the positioning gear 2 is meshed with the corresponding positioning rack 2 to form a gear rack pair.

[0007] Furthermore, the driving unit also includes a driving gear ring and three driving gears. The driving gear ring is movably connected to the three arc-shaped long plates. The three driving gears are respectively fixedly connected to the corresponding adjustment gear 1 and adjustment rack 2. The driving gears are all meshed with the driving gear ring to form a gear pair.

[0008] Furthermore, a lifting ring plate is slidably installed on the transposition ring frame, and the ends of the arc-shaped long plate closest to the lifting ring plate are fixedly connected to the lifting ring plate. Three auxiliary long plates are movably arranged in a circular array on the lifting ring plate, and the outer circumferential surface of the circular scraper, the inner circumferential surface of the mixing cylinder, and the surface of the auxiliary long plate farthest from the axis of the circular scraper are on the same circumferential surface.

[0009] Furthermore, the auxiliary long plates are slidably matched with the circular scraper. When the stirring straight plate moves to directly below the auxiliary long plate, the projections of the stirring straight plate and the auxiliary long plate on the lower surface of the base overlap. A cleaning screw is fixedly installed on the circular scraper, and a transmission long shaft is rotatably installed on the transposition ring frame. The cleaning screw and the transmission long shaft constitute a spiral pair.

[0010] Furthermore, the auxiliary slide is slidably installed on the transposition ring frame, and a U-shaped slide is fixedly installed on the surface of the semicircular cover plate farthest from the circular scraper. The two U-shaped slides are correspondingly slidably installed on the auxiliary slide. When the two semicircular cover plates are joined, a complete circular plate is formed. The diameter of the circular plate formed when the two semicircular cover plates are joined is equal to the inner diameter of the semicircular cover plate.

[0011] Furthermore, when the circular plate formed by joining the two semicircular cover plates is joined with the mixing cylinder, a closed chamber is formed inside the mixing cylinder, the semicircular cover plates, the arc-shaped long plate and the circular scraper.

[0012] Compared with the prior art, the present invention has the following beneficial effects: (1) By providing a driving unit, the present invention can change the position of the stirring straight plate during the stirring of the raw materials by the stirring straight plate, thereby improving the mixing effect of the raw materials, and can also make the stirring straight plate corresponding to the lifting slide plate 1 move to the position where the axis of the mixing cylinder is located, thereby preventing the raw materials in the central area of ​​the mixing cylinder from being unable to be stirred and mixed. (2) By providing the lifting slide plate 1 and the lifting slide plate 2, the present invention can make the lifting slide plate 1 and the lifting slide plate 2 move up and down in the mixing cylinder under the action of the lifting ring plate, thereby further improving the mixing effect of the raw materials. (3) By providing an auxiliary long plate, the present invention can scrape off the raw materials attached to the inner wall of the mixing cylinder, and can also scrape off the raw materials attached to the semicircular cover plate and the circular scraper under the action of the lifting slide plate 1, thereby preventing this part of the raw materials from being unable to be mixed. (4) By providing a cleaning component, the present invention can scrape off the high-viscosity drug preparation attached to the mixing cylinder, the stirring straight plate, and the arc-shaped long plate, thereby facilitating the removal of the prepared high-viscosity drug preparation. (5) The present invention can achieve homogeneous mixing of raw materials through the cooperation of the stirring component, the cleaning component, and the covering component, thereby improving the mixing effect of the raw materials and further improving the quality of the prepared high-viscosity pharmaceutical preparation. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0014] Figure 2 It is a schematic structural diagram of the covering assembly of the present invention.

[0015] Figure 3 It is a structural schematic diagram of the semicircular cover plate of the present invention.

[0016] Figure 4 It is a structural schematic diagram of the transposition ring frame of the present invention.

[0017] Figure 5 for Figure 4 A local enlarged schematic diagram of point A in the middle.

[0018] Figure 6 It is a structural schematic diagram of the circular scraper of the present invention.

[0019] Figure 7 for Figure 6 A local enlarged schematic diagram of point B in the middle.

[0020] Figure 8 It is a schematic structural diagram of the driving unit of the present invention.

[0021] Fig. 9 for Figure 8 A partial enlarged schematic diagram of point C in the middle.

[0022] Fig.10 for Figure 8 A partial enlarged schematic diagram of point D in the middle.

[0023] Fig.11 It is a top view of the driving unit of the present invention.

[0024] Fig.12 It is a cross-sectional view of the structure of the mixing cylinder of the present invention.

[0025] Figure numerals: 101-base; 102-transposition circular plate; 103-transposition motor; 104-transposition ring frame; 105-mixing cylinder; 106-semicircular cover plate; 107-U-shaped slide plate; 108-auxiliary slide frame; 109-double-threaded screw rod; 110-separation motor; 111-auxiliary screw rod; 112-auxiliary motor; 113-arc long plate; 114-lifting slide plate 1; 115-circular scraper; 116-stirring straight plate; 117-stirring motor ; 118-stirring gear; 119-lifting motor; 120-lifting screw; 121-driving gear ring; 122-cleaning screw; 123-lifting ring plate; 124-transmission long shaft; 125-cleaning motor; 126-auxiliary long plate; 127-adjusting rack one; 128-driving motor; 129-adjusting gear one; 130-driving gear; 131-lifting slide plate two; 132-adjusting gear two; 133-adjusting rack two; 134-stirring gear ring. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0027] Example: Reference Figure 1-Figure 12 A stirring and mixing device for high-viscosity drug preparations includes a base 101, a transposition ring frame 104 is movably arranged on the base 101, a transposition circular plate 102 is fixedly arranged on the side of the transposition ring frame 104, the transposition circular plate 102 is rotatably mounted on the base 101, the transposition circular plate 102 is fixedly mounted on the base 101, the output shaft of the transposition circular plate 102 is fixedly connected to a transposition motor 103, a mixing cylinder 105 is rotatably mounted on the transposition ring frame 104, a stirring gear ring 134 is fixedly mounted on the mixing cylinder 105, a stirring motor 117 is fixedly mounted on the transposition ring frame 104, a stirring gear 118 is fixedly mounted on the output shaft of the stirring motor 117, and the stirring gear 118 and the stirring gear ring 134 are meshed to form a gear pair.

[0028] Start the transposition motor 103 to drive the transposition circular plate 102 to rotate, so that the transposition ring frame 104 rotates relative to the axis of the transposition motor 103, start the stirring motor 117 to drive the stirring gear 118 to rotate, and under the action of the stirring gear ring 134, the mixing cylinder 105 rotates relative to the axis of the transposition ring frame 104, and the axes of the transposition ring frame 104, the mixing cylinder 105 and the stirring gear ring 134 are on the same straight line.

[0029] The mixing cylinder 105 is provided with a stirring assembly, which includes a lifting slide plate 114 and two lifting slide plates 131. The mixing cylinder 105 is provided with three arc-shaped long plates 113 in a sliding manner in a circumferential array. The arc surface of the arc-shaped long plate 113 closest to the axis of the mixing cylinder 105 and the circumferential surface inside the mixing cylinder 105 are on the same circumferential surface. There is no gap between the two sides of the semicircular cover plate 106 and the mixing cylinder 105, that is, at this time, the circumferential surface inside the mixing cylinder 105 is a complete circumferential surface. The lifting ring plate 123 is slidably installed on the transposition ring frame 104. The arc-shaped long plate 113 is provided with a lifting ring plate 123 in a slidable manner in a circumferential array ... The ends closest to the lifting ring plate 123 are fixedly connected to the lifting ring plate 123. A lifting screw 120 is rotatably mounted on the mixing cylinder 105. A lifting motor 119 is fixedly mounted on the mixing cylinder 105. The output shaft of the lifting motor 119 is fixedly connected to the lifting screw 120. The lifting motor 119 is started to drive the lifting screw 120 to rotate, so that the lifting ring plate 123 moves along the axis of the lifting screw 120. Under the action of the lifting ring plate 123, the three arc-shaped long plates 113 move synchronously, so that the arc-shaped long plates 113 slide relative to the mixing cylinder 105.

[0030] The lifting slide 1 114 and the two lifting slides 131 are respectively slidably installed on the corresponding arc-shaped long plates 113. The lifting slide 114 and the two lifting slides 131 are arranged in a circular array relative to the axis of the mixing cylinder 105. The ends of the lifting slide 114 and the lifting slide 131 closest to the axis of the mixing cylinder 105 are both slidably installed with stirring straight plates 116. A driving unit is arranged between the lifting slide 1 114 and the two lifting slides 131. The driving unit is used to make the displacement of the lifting slide 114 twice the displacement of the lifting slide 2 131.

[0031] The driving unit includes a positioning gear 129 and two positioning gears 132. The positioning gear 129 and the two positioning gears 132 are respectively rotatably mounted on the corresponding arc-shaped long plate 113. The side of the lifting slide 114 is fixedly mounted with a positioning rack 127. The side of the lifting slide 131 is fixedly mounted with a positioning rack 133. The positioning rack 127 and the positioning gear 129 are meshed to form a gear rack pair. The positioning gear 132 is meshed with the corresponding positioning rack 133 to form a gear rack pair. The driving unit also includes a driving gear ring 121 and three driving gears 130. The driving gear ring 121 is movably connected to the three arc-shaped long plates 113. The three driving gears 130 are respectively fixedly connected to the corresponding positioning gear 1 129 and the positioning rack 2 133. The driving gears 130 are all meshed with the driving gear ring 121 to form a gear pair. A driving motor 128 is fixedly installed on the arc-shaped long plate 113 on which the positioning gear 1 129 is rotatably installed, and the output shaft of the driving motor 128 is fixedly connected to the positioning gear 1 129.

[0032] The driving motor 128 is started to drive the adjusting gear 129 to rotate, and the driving gear 130 corresponding to the adjusting gear 129 rotates synchronously. Under the action of the driving gear ring 121, the three driving gears 130 rotate synchronously, thereby causing the adjusting gear 129 and the two adjusting gears 132 to rotate synchronously, and then under the action of the adjusting rack 127 and the adjusting rack 133, the lifting slide 114 and the two lifting slides 131 move synchronously toward the direction close to the axis of the mixing cylinder 105 or synchronously. Move in the direction away from the axis of the mixing cylinder 105, that is, the three stirring straight plates 116 are synchronously moved in the direction close to the axis of the mixing cylinder 105 or synchronously moved in the direction away from the axis of the mixing cylinder 105. Under the effect of the transmission ratio between the positioning rack 127 and the positioning gear 129 and the transmission ratio between the positioning gear 2 132 and the positioning rack 2 133, when the lifting slide 114 and the lifting slide 2 131 are moving, the displacement of the lifting slide 114 is twice the displacement of the lifting slide 2 131.

[0033] A cleaning assembly is provided on the mixing cylinder 105, and the cleaning assembly includes a circular scraper 115, which is slidably mounted on the transposition ring frame 104, and the diameter of the circular scraper 115 is equal to the inner diameter of the mixing cylinder 105. The circular scraper 115 is used to scrape and clean the attachments on the stirring straight plate 116 and the inner wall of the mixing cylinder 105. A cleaning screw 122 is fixedly mounted on the circular scraper 115, and a transmission long shaft 124 is rotatably mounted on the transposition ring frame 104. The cleaning screw 122 and the transmission long shaft 124 constitute a spiral pair, and a cleaning motor 125 is fixedly mounted on the transposition ring frame 104. Pulleys are fixedly mounted on the output shaft of the cleaning motor 125 and the transmission long shaft 124, and a belt is arranged between the pulley on the output shaft of the cleaning motor 125 and the pulley on the transmission long shaft 124.

[0034] The cleaning motor 125 is started to drive the transmission shaft 124 to rotate, so that the cleaning screw 122 moves relative to the axis of the transmission shaft 124, thereby causing the circular scraper 115 to slide relative to the mixing cylinder 105.

[0035] Three auxiliary long plates 126 are movably arranged in a circular array on the lifting ring plate 123. The outer circumferential surface of the circular scraper 115, the inner circumferential surface of the mixing cylinder 105, and the surface of the auxiliary long plates 126 farthest from the axis of the circular scraper 115 are on the same circumferential surface. The auxiliary long plates 126 are slidably matched with the circular scraper 115. When the stirring straight plate 116 moves to directly below the auxiliary long plates 126, the projections of the stirring straight plate 116 and the auxiliary long plates 126 on the lower surface of the base 101 overlap.

[0036] In the initial position, the lifting slide plate 114 and the lifting slide plate 2 131 are both located at the farthest position from the axis of the mixing cylinder 105, that is, at this time, the three stirring straight plates 116 are all located at the farthest position from the axis of the mixing cylinder 105, the surface of the stirring straight plate 116 farthest from the axis of the mixing cylinder 105 and the inner circumferential surface of the mixing cylinder 105 are on the same circumferential surface, and the lifting ring plate 123 is located at the farthest position from the mixing cylinder 105. At this time, the end surface of the arc-shaped long plate 113 farthest from the lifting ring plate 123 and the mixing cylinder 1 05The end surface farthest from the lifting ring plate 123 is on the same plane, the end surface farthest from the lifting ring plate 123 of the auxiliary long plate 126 and the surface closest to the lifting ring plate 123 of the circular scraper 115 are on the same plane, the lifting slide 1 114 and the lifting slide 2 131 are both located at the farthest positions from the lifting ring plate 123, and at this time, the surfaces of the lifting slide 1 114 and the lifting slide 2 131 closest to the lifting ring plate 123 and the surface of the circular scraper 115 farthest from the lifting ring plate 123 are on the same plane.

[0037] The stirring motor 117 is started to drive the mixing cylinder 105 to rotate, that is, the mixing cylinder 105 rotates relative to the circular scraper 115, and the arc-shaped long plate 113, the lifting slide plate 1 14, the stirring straight plate 116, and the lifting slide plate 2 131 all rotate relative to the circular scraper 115. At this time, the auxiliary long plate 126 and the circular scraper 115 are in a state of engagement, that is, at this time, the lifting ring plate 123 rotates relative to the auxiliary long plate 126, and finally the auxiliary long plate 126 moves to the top of the corresponding stirring straight plate 116, that is, at this time, the positions of the three auxiliary long plates 126 and the three stirring straight plates 116 correspond one to one, and then the cleaning motor 125 is started to drive The circular scraper 115 moves in the direction away from the lifting ring plate 123, so that the circular scraper 115 gradually disengages from the auxiliary long plate 126, and the joint between the circular scraper 115 and the auxiliary long plate 126 engages with the corresponding stirring straight plate 116. When the joint between the circular scraper 115 and the auxiliary long plate 126 is completely disengaged from the auxiliary long plate 126, the joint between the circular scraper 115 and the auxiliary long plate 126 is completely engaged with the stirring straight plate 116, and the circular scraper 115 continues to move in the direction away from the lifting ring plate 123. Under the action of the circular scraper 115, the attachments on the inner wall of the mixing cylinder 105 and the stirring straight plate 116 are scraped off.

[0038] The stirring motor 117 is started to drive the mixing cylinder 105 to rotate, so that the mixing cylinder 105, the arc-shaped long plate 113, the lifting slide 114, the stirring straight plate 116, and the lifting slide 2 131 rotate synchronously. Under the action of the lifting slide 114, the stirring straight plate 116, and the lifting slide 2 131, the high-viscosity drug preparation raw materials inside the mixing cylinder 105 are stirred and mixed. In the process of stirring the high-viscosity drug preparation raw materials by the lifting slide 114, the stirring straight plate 116, and the lifting slide 2 131, the driving motor 128 is started to drive the lifting slide 114 and the lifting slide 2 131 to move, so that the stirring straight plate 116 slides relative to the axis of the mixing cylinder 105.

[0039] The transposition ring frame 104 is also provided with a covering assembly, which includes an auxiliary slide 108, on which a semicircular cover plate 106 is symmetrically and movably provided, and the two semicircular cover plates 106 are used to cover the end of the mixing cylinder 105, and the auxiliary slide 108 is slidably mounted on the transposition ring frame 104, and an auxiliary screw rod 111 is rotatably mounted on the auxiliary slide 108, and the auxiliary screw rod 111 and the transposition ring frame 104 form a spiral pair, and an auxiliary motor 112 is fixedly mounted on the auxiliary slide 108, and the output shaft of the auxiliary motor 112 is fixedly connected to the auxiliary screw rod 111, and the semicircular cover plate 106 is 100 meters away from the circular scraper 1 A U-shaped slide 107 is fixedly mounted on the farthest surface of 15, and two U-shaped slides 107 are correspondingly slidably mounted on an auxiliary slide 108. When the two semicircular cover plates 106 are joined, a complete circular plate is formed. The diameter of the circular plate formed when the two semicircular cover plates 106 are joined is equal to the inner diameter of the semicircular cover plates 106. A double-threaded screw rod 109 is rotatably mounted on the auxiliary slide 108, and the threads at both ends of the double-threaded screw rod 109 respectively form a spiral pair with the corresponding U-shaped slides 107. A separation motor 110 is fixedly mounted on the auxiliary slide 108, and the output shaft of the separation motor 110 is fixedly connected to the double-threaded screw rod 109.

[0040] When the circular plate formed by the two semicircular cover plates 106 is joined to the mixing cylinder 105, a closed chamber is formed inside the mixing cylinder 105, the semicircular cover plates 106, the arc-shaped long plate 113, and the circular scraper 115. When a closed chamber is formed inside the mixing cylinder 105, the semicircular cover plates 106, the arc-shaped long plate 113, and the circular scraper 115, the two ends of the stirring straight plate 116 are in contact with the semicircular cover plates 106 and the circular scraper 115 respectively.

[0041] Working principle: Start the transposition motor 103 to drive the transposition circular plate 102 and the transposition ring frame 104 to rotate synchronously, so that the semicircular cover plate 106 moves to the top of the circular scraper 115, that is, at this time the circular scraper 115 is located at the position closest to the lower surface of the base 101, and then start the auxiliary motor 112 to drive the auxiliary screw 111 to rotate, so that the auxiliary slide 108 moves upward, and finally the lower surface of the semicircular cover plate 106 moves to the top of the upper surface of the mixing cylinder 105, and then start the separation motor 110 to drive the double-headed threaded screw 109 to rotate, so that the two U-shaped slides 107 move away from each other, and then the two semicircular cover plates 106 move away from each other, and finally the two semicircular cover plates 106 move to both sides of the mixing cylinder 105, at this time the upper end surface of the arc-shaped long plate 113 and the upper end surface of the mixing cylinder 105 are on the same plane.

[0042] Then, the raw materials for preparing high-viscosity drug preparations are placed into the interior of the cylinder formed by the mixing cylinder 105, the arc-shaped long plate 113, and the circular scraper 115. After the raw materials are added, the separation motor 110 and the auxiliary motor 112 are started, so that the two stirring straight plates 116 are joined to form a complete circular plate and the circular plate is joined to the mixing cylinder 105. That is, at this time, a closed chamber is formed inside the mixing cylinder 105, the semicircular cover plate 106, the arc-shaped long plate 113, and the circular scraper 115.

[0043] Then, the stirring motor 117 is started to drive the mixing cylinder 105 to rotate, and the lifting slide plate 114, the stirring straight plate 116, and the lifting slide plate 2 131 are moved synchronously, so that the stirring straight plate 116 stirs the raw materials in the sealed chamber, and the driving motor 128 is started to move the stirring straight plate 116 relative to the axis of the mixing cylinder 105, that is, the position of the stirring straight plate 116 is changed during the stirring of the raw materials in the sealed chamber by the stirring straight plate 116, thereby improving the stirring effect of the stirring straight plate 116 on the raw materials, thereby improving the mixing effect of the raw materials, and the lifting motor 119 is started to move the lifting ring plate 123 downward, so that the arc-shaped long plate 113 and the auxiliary long plate 126 are moved downward synchronously, so that the auxiliary long plate 126 moves to the inside of the sealed chamber. During the rotation process of the mixing cylinder 105 In the embodiment, the auxiliary long plate 126 cannot rotate synchronously with the mixing cylinder 105, so that the auxiliary long plate 126 scrapes off the attachments on the inner wall of the mixing cylinder 105, thereby preventing the raw materials from adhering to the inner wall of the mixing cylinder 105 and being unable to be mixed, and the lifting slide 114 and the lifting slide 2 131 move up and down under the action of the lifting ring plate 123, so that the lifting slide 114 and the lifting slide 2 131 lift and move the raw materials inside the closed chamber up and down, thereby improving the mixing effect of the raw materials. Since the displacement of the lifting slide 114 is twice the displacement of the lifting slide 2 131, the stirring straight plate 116 corresponding to the lifting slide 114 can be moved to the axial position of the mixing cylinder 105, thereby preventing the raw materials in the central area of ​​the mixing cylinder 105 from being stirred and mixed by the stirring straight plate 116.

[0044] The position of the lifting ring plate 123 is controlled so that the lifting slide 114 and the lifting slide 2 131 are in contact with the lower surface of the circular scraper 115, that is, the attachments on the lower surface of the circular scraper 115 are scraped off, and the lifting slide 114 and the lifting slide 2 131 are in contact with the upper surface of the semicircular cover plate 106, that is, the attachments on the upper surface of the semicircular cover plate 106 are scraped off, so that the raw materials in the closed chamber can be fully mixed.

[0045] After the raw materials in the closed chamber are mixed, the transposition motor 103 is started to rotate the semicircular cover plate 106 to be directly below the circular scraper 115, and then the collecting cylinder is placed directly below the mixing cylinder 105, and then the lifting ring plate 123 is moved to the position farthest from the semicircular cover plate 106. At this time, the end surface of the arc-shaped long plate 113 farthest from the lifting ring plate 123 and the end surface of the mixing cylinder 105 farthest from the lifting ring plate 123 are on the same plane, and then the auxiliary motor 112 is started to make the surface of the semicircular cover plate 106 closest to the circular scraper 115 and the surface of the mixing cylinder 105 farthest from the circular scraper 115 on the same plane, and then the separation motor 110 is started to make the two semicircular cover plates 106 move away from each other. Under the action of the mixing cylinder 105, the attached materials on the semicircular cover plates 106 are The objects are scraped off, and the high-viscosity drug preparation in the mixing cylinder 105 falls into the collecting cylinder below, and then the stirring motor 117 and the driving motor 128 are started, so that the stirring straight plate 116 moves to the position farthest from the axis of the mixing cylinder 105, and the stirring straight plate 116 moves to just below the corresponding auxiliary long plate 126, and then the cleaning motor 125 is started to drive the circular scraper 115 to move downward, and the circular scraper 115 scrapes off the high-viscosity drug preparation attached to the mixing cylinder 105, the arc-shaped long plate 113, and the stirring straight plate 116, and finally makes the lower surface of the circular scraper 115 and the lower surface of the mixing cylinder 105 on the same plane, and then the staff scrapes off the high-viscosity drug preparation attached to the lower surface of the circular scraper 115, that is, all the high-viscosity drug preparation mixed by the device is taken out.

[0046] The present invention is not limited to the above-mentioned specific implementation modes. Various changes made by technicians in the relevant technical field based on the above-mentioned conception without creative work all fall within the protection scope of the present invention.

Claims

1. A stirring and mixing device for a high-viscosity pharmaceutical preparation, comprising a base (101), characterized in that: The base (101) is movably provided with a transposition ring frame (104), a mixing cylinder (105) is rotatably mounted on the transposition ring frame (104), a stirring assembly and a cleaning assembly are arranged on the mixing cylinder (105), the stirring assembly comprises a lifting slide plate 1 (114) and two lifting slide plates 2 (131), three arc-shaped long plates (113) are slidably mounted in a circular array on the mixing cylinder (105), the lifting slide plate 1 (114) and the two lifting slide plates 2 (131) are respectively slidably mounted on corresponding arc-shaped long plates (113), and the lifting slide plate The ends of the first lifting slide (114) and the second lifting slide (131) closest to the axis of the mixing cylinder (105) are both slidably mounted with a stirring straight plate (116); a driving unit is provided between the first lifting slide (114) and the two second lifting slides (131); the driving unit is used to make the displacement of the first lifting slide (114) twice the displacement of the second lifting slide (131); the cleaning component comprises a circular scraper (115); the circular scraper (115) is used to scrape and clean the attachments on the stirring straight plate (116) and the inner wall of the mixing cylinder (105); A lifting ring plate (123) is slidably mounted on the transposition ring frame (104), and the ends of the arc-shaped long plates (113) closest to the lifting ring plate (123) are fixedly connected to the lifting ring plate (123); The transposition ring frame (104) is also provided with a covering assembly, which includes an auxiliary slide (108), and semicircular cover plates (106) are symmetrically and movably provided on the auxiliary slide (108), and the two semicircular cover plates (106) are used to cover the end of the mixing cylinder (105).

2. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 1, characterized in that: A transposition circular plate (102) is fixedly provided on the side of the transposition ring frame (104), and the transposition circular plate (102) is rotatably mounted on the base (101). The arc surface of the arc-shaped long plate (113) closest to the axis of the mixing cylinder (105) and the circumferential surface inside the mixing cylinder (105) are on the same circumferential surface, and there is no gap between the two sides of the semicircular cover plate (106) and the mixing cylinder (105).

3. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 2, characterized in that: The driving unit comprises a positioning gear 1 (129) and two positioning gear 2s (132), wherein the positioning gear 1 (129) and the two positioning gear 2s (132) are respectively rotatably mounted on the corresponding arc-shaped long plates (113), a positioning rack 1 (127) is fixedly mounted on the side of the lifting slide plate 1 (114), and a positioning rack 2 (133) is fixedly mounted on the side of the lifting slide plate 2 (131), the positioning rack 1 (127) and the positioning gear 1 (129) are meshed to form a gear rack pair, and the positioning gear 2 (132) is meshed with the corresponding positioning rack 2 (133) to form a gear rack pair.

4. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 3, characterized in that: The driving unit further comprises a driving gear ring (121) and three driving gears (130); the driving gear ring (121) is movably connected to the three arc-shaped long plates (113); the three driving gears (130) are respectively fixedly connected to the corresponding positioning gear 1 (129) and positioning rack 2 (133); the driving gears (130) are all meshed with the driving gear ring (121) to form a gear pair.

5. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 4, characterized in that: The lifting ring plate (123) is provided with three auxiliary long plates (126) in a movable circular array, and the outer circumferential surface of the circular scraper (115), the inner circumferential surface of the mixing cylinder (105), and the surface of the auxiliary long plate (126) farthest from the axis of the circular scraper (115) are on the same circumferential surface.

6. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 5, characterized in that: The auxiliary long plates (126) are slidably matched with the circular scraper (115). When the stirring straight plate (116) moves to the position directly below the auxiliary long plates (126), the projections of the stirring straight plate (116) and the auxiliary long plates (126) on the lower surface of the base (101) overlap. A cleaning screw (122) is fixedly mounted on the circular scraper (115). A transmission long shaft (124) is rotatably mounted on the transposition ring frame (104). The cleaning screw (122) and the transmission long shaft (124) form a spiral pair.

7. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 6, characterized in that: The auxiliary slide (108) is slidably mounted on the transposition ring frame (104); a U-shaped slide plate (107) is fixedly mounted on the surface of the semicircular cover plate (106) farthest from the circular scraper (115); two U-shaped slide plates (107) are correspondingly slidably mounted on the auxiliary slide (108); a complete circular plate is formed when the two semicircular cover plates (106) are joined; and a diameter of the circular plate formed when the two semicircular cover plates (106) are joined is equal to an inner diameter of the semicircular cover plates (106).

8. A stirring and mixing device for high-viscosity pharmaceutical preparations according to claim 7, characterized in that: When the circular plate formed by joining the two semicircular cover plates (106) is joined to the mixing cylinder (105), a closed chamber is formed inside the mixing cylinder (105), the semicircular cover plates (106), the arc-shaped long plate (113), and the circular scraper (115).

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