Bee venom traditional Chinese medicine combined preparation for treating rheumatic arthritis and preparation method thereof

Abstract

The invention belongs to the technical field of bee venom traditional Chinese medicine combined preparations, and particularly relates to a bee venom traditional Chinese medicine combined preparation for treating rheumatic arthritis and a preparation method thereof. The bee venom oral liquid is prepared from the following raw materials in percentage by mass: 26% of bee venom extracting solution, 1%-1.5% of clove extracting solution, 18%-20% of propolis extracting solution, 1%-3% of murraya paniculata extracting solution, 20%-25% of cinnamon extracting solution, 8%-10% of radix aconiti agrestis extracting solution, 12%-15% of safflower extracting solution, 8%-10% of radix curcumae extracting solution and 6%-10% of myrrh extracting solution. Through reasonable traditional Chinese medicine proportioning and bee venom combination, the drug effect of bee venom is enhanced, and the cure rate of rheumatic patients is increased; the method of externally coating the preparation is convenient for patients to use, the treatment risk of bee venom therapy is reduced, and the self-treatment of the patients at home is facilitated.

Description

Technical Field

[0001] The invention belongs to the technical field of bee venom Chinese medicine combination preparations, and particularly relates to a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis and a preparation method thereof. Background Art

[0002] The occurrence of rheumatoid arthritis is an immune response caused by hemolytic streptococcal infection. Severe patients have bone and joint deformation, redness and swelling of joints, and are at risk of loss of joint function. Moreover, the disease is a migratory disease with strong recurrence and is difficult to treat thoroughly. Currently, most medical fields use surgery, antibiotics, and hormone drugs to treat and control the disease. After stopping the medication, the disease will recur. Even with surgical treatment, the high probability of recurrence risk cannot be avoided. In addition, bee sting therapy uses bee venom to treat rheumatoid arthritis in the private sector and some medical institutions, but there are still some shortcomings. For example, the sensitization rate is high, which will cause shock to the patient and there is a certain risk of use; the treatment process is relatively complicated, the treatment efficiency is low, and it imposes a certain burden on the patient's energy and financial resources. Summary of the invention

[0003] In view of the above-mentioned deficiencies in the prior art, the present invention provides a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis and a preparation method thereof, so as to solve the above-mentioned existing problems.

[0004] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0005] A bee venom Chinese medicine combination preparation for treating rheumatoid arthritis is prepared from the following raw materials in percentage by mass: 26% of honey bee venom extract, 1%-1.5% of clove extract, 18%-20% of propolis extract, 1%-3% of Murraya osmanthus extract, 20%-25% of cinnamon extract, 8%-10% of aconite extract, 12%-15% of safflower extract, 8%-10% of curcuma extract, and 6%-10% of myrrh extract;

[0006] Preferably, a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis is made of the following percentages by mass of raw materials: 26% bee venom extract, 1% clove extract, 18% propolis extract, 1% Murraya extract, 20% cinnamon extract, 8% aconite extract, 12% safflower extract, 8% turmeric extract, 6% myrrh extract. It is made of the following percentages by mass of raw materials: 26% bee venom extract, 1% clove extract, 18% propolis extract, 1% Murraya extract, 20% cinnamon extract, 8% aconite extract, 12% safflower extract, 8% turmeric extract, 6% myrrh extract;

[0007] A method for preparing a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis comprises the following steps:

[0008] S1. Dissolve the bee venom freeze-dried powder in purified water at a ratio of 1:20 and place in a fresh-keeping box for later use;

[0009] S2. Weigh the above raw materials according to their weight, crush them into 2-3 mm particles and pour them into an unsealed stainless steel storage tank for later use;

[0010] S3, add yeast, 5% sorghum and 50% purified water in proportion and ferment at room temperature for 21 days, stirring evenly once a day during the fermentation process;

[0011] S4. After 21 days of fermentation, add 50% ethanol and stir evenly. Stir twice a day for 5 consecutive days.

[0012] S5, filtering the drug residue and introducing it into a material storage tank for standby use;

[0013] S6, mixing the alcoholized propolis with a purity of 99% with the inner material after filtering in step 5 according to a certain proportion and letting it stand for 2 days;

[0014] S7, adding honey bee venom according to proportion to prepare a bee venom Chinese medicine combination preparation;

[0015] S8. Fill the prepared bee venom Chinese medicine combination preparation, sterilize it with high-pressure steam in the purification area, and then fill and seal it.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] 1. The present invention enhances the efficacy of bee venom and improves the cure rate of rheumatic patients through a reasonable combination of Chinese medicine ratio and bee venom; the external application preparation is used to make it convenient for patients to use, reduce the risk of bee venom therapy, and facilitate patients to self-treat at home;

[0018] 2. The present invention can treat joint pain, swelling and other related symptoms caused by rheumatism and rheumatoid arthritis, and has good inhibitory and killing effects on bacteria and inflammation on the surface of the skin as tested by a third party. By adding bee venom and propolis extract, the user's immune function to hemolytic streptococci can be effectively improved, and the disease resistance can be enhanced. DETAILED DESCRIPTION

[0019] In order to enable those skilled in the art to better understand the present invention, the technical solution of the present invention is further described below in conjunction with embodiments.

[0020] Example:

[0021] The invention discloses a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis, which is prepared from the following raw materials in percentage by mass: 26% of bee venom extract, 1%-1.5% of clove extract, 18%-20% of propolis extract, 1%-3% of Murraya odorifera extract, 20%-25% of cinnamon bark extract, 8%-10% of Aconitum kusnezoffii extract, 12%-15% of safflower extract, 8%-10% of Curcuma aromatica extract, and 6%-10% of myrrh extract;

[0022] Preferably, a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis is made of the following percentages by mass of raw materials: 26% bee venom extract, 1% clove extract, 18% propolis extract, 1% Murraya extract, 20% cinnamon extract, 8% aconite extract, 12% safflower extract, 8% turmeric extract, 6% myrrh extract. It is made of the following percentages by mass of raw materials: 26% bee venom extract, 1% clove extract, 18% propolis extract, 1% Murraya extract, 20% cinnamon extract, 8% aconite extract, 12% safflower extract, 8% turmeric extract, 6% myrrh extract;

[0023] A method for preparing a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis comprises the following steps:

[0024] S1. Dissolve the bee venom freeze-dried powder in purified water at a ratio of 1:20 and place in a fresh-keeping box for later use;

[0025] S2. Weigh the above raw materials according to their weight, crush them into 2-3 mm particles and pour them into an unsealed stainless steel storage tank for later use;

[0026] S3, add yeast, 5% sorghum and 50% purified water in proportion and ferment at room temperature for 21 days, stirring evenly once a day during the fermentation process;

[0027] S4. After 21 days of fermentation, add 50% ethanol and stir evenly. Stir twice a day for 5 consecutive days.

[0028] S5, filtering the drug residue and introducing it into a material storage tank for standby use;

[0029] S6, mixing the alcoholized propolis with a purity of 99% with the inner material after filtering in step 5 according to a certain proportion and letting it stand for 2 days;

[0030] S7, adding honey bee venom according to proportion to prepare a bee venom Chinese medicine combination preparation;

[0031] S8. Fill the prepared bee venom Chinese medicine combination preparation, sterilize it with high-pressure steam in the purification area, and then fill and seal it.

[0032] The above are only embodiments of the present invention. The common knowledge such as the known specific structures and characteristics in the scheme is not described in detail here. The ordinary technicians in the relevant field are aware of all the common technical knowledge in the technical field of the invention before the application date or priority date, can obtain all the existing technologies in the field, and have the ability to apply the conventional experimental means before that date. The ordinary technicians in the relevant field can improve and implement the scheme in combination with their own abilities under the enlightenment given by this application. Some typical known structures or known methods should not become obstacles for the ordinary technicians in the relevant field to implement this application. It should be pointed out that for the technicians in this field, without departing from the structure of the present invention, several deformations and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent.

[0033] In the description of the present invention, unless otherwise clearly specified and limited, if the term "connection" or the like appears to indicate the connection relationship between components, the term should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two components or the interaction relationship between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. A bee venom Chinese medicine combination preparation for treating rheumatoid arthritis, characterized in that: The invention is prepared from the following raw materials in percentage by weight: 26% of bee venom extract, 1%-1.5% of clove extract, 18%-20% of propolis extract, 1%-3% of osmanthus fragrans extract, 20%-25% of cinnamon bark extract, 8%-10% of aconite extract, 12%-15% of safflower extract, 8%-10% of turmeric extract and 6%-10% of myrrh extract.

2. A bee venom Chinese medicine combination preparation for treating rheumatoid arthritis as claimed in claim 1, characterized in that: The invention is prepared from the following raw materials in percentage by mass: 26% of bee venom extract, 1% of clove extract, 18% of propolis extract, 1% of osmanthus fragrans extract, 20% of cinnamon extract, 8% of aconite extract, 12% of safflower extract, 8% of turmeric extract and 6% of myrrh extract.

3. The method for preparing a bee venom Chinese medicine combination preparation for treating rheumatoid arthritis according to claim 1, characterized in that: The steps include: S1. Dissolve the bee venom freeze-dried powder in purified water at a ratio of 1:20 and place in a fresh-keeping box for later use; S2. Weigh the above raw materials according to their weight, crush them into 2-3 mm particles and pour them into an unsealed stainless steel storage tank for later use; S3, add yeast, 5% sorghum and 50% purified water in proportion and ferment at room temperature for 21 days, stirring evenly once a day during the fermentation process; S4. After 21 days of fermentation, add 50% ethanol and stir evenly. Stir twice a day for 5 consecutive days. S5, filtering the drug residue and introducing it into a material storage tank for standby use; S6, mixing the alcoholized propolis with a purity of 99% with the inner material after filtering in step 5 according to a certain proportion and letting it stand for 2 days; S7, adding honey bee venom according to proportion to prepare a bee venom Chinese medicine combination preparation; S8. Fill the prepared bee venom Chinese medicine combination preparation, sterilize it with high-pressure steam in the purification area, and then fill and seal it.