Multifunctional mouse simulation exercise device and use method

Abstract

The invention belongs to the technical field of mouse simulation, and discloses a multifunctional mouse simulation exercise device and a using method thereof, and the multifunctional mouse simulation exercise device is characterized in that a trunk structure is arranged at the top end of a tail structure; a lung structure is arranged in the front 1 / 3 of the trunk structure, and a stomach structure is arranged in the center; the top of the trunk structure is provided with a head structure. The multifunctional mouse simulation practice device can provide a training scene close to practical operation practice for a user at relatively low cost, and has the characteristics of relatively low and controllable cost, relatively low environment dependence, high resource reuse rate, relatively good training platform consistency and the like compared with a real mouse experiment; the method can effectively supplement intermediate training links between theoretical learning and in-vivo experiments, thereby cultivating operation standard consciousness of related personnel, improving practical operation proficiency, further reducing dosage expectation of experimental animals, saving experimental resources, and improving the welfare level of the experimental animals.

Description

Technical Field

[0001] The present invention belongs to the technical field of rodent simulation, and in particular to a multifunctional rodent simulation training device and a method of using the same. The present invention belongs to the technical field of animal medicine teaching equipment, and in particular to a multifunctional rodent simulation training device and a method of using the same, which are suitable for animal medicine teaching and experimental operation training of scientific researchers. Background Art

[0002] Models have been widely used in human medical education and have achieved good results. However, in animal medicine education, most experimental operations rely on live rodents. This not only increases the consumption of experimental resources, but may also cause unnecessary harm to experimental animals.

[0003] Therefore, it is urgent to develop a rodent operation model. By using animal medical models in teaching, students can improve their operation standards and proficiency through animal medical model training, and then conduct practical operations on live animals. This can not only reduce the waste of resources caused by unskilled operation, but also improve teaching efficiency and animal welfare. The use of animal medical models will greatly improve the level of animal welfare, and can also provide practical training resources for the reform of teaching and assessment models, and effectively improve teaching efficiency. The promotion and use of these models will help promote changes in teaching methods and models for similar majors across the country.

[0004] Through the above analysis, the problems and defects of the prior art are as follows:

[0005] In traditional medicine, live mice are generally used for operation and practice, but this results in a waste of resources and may cause unnecessary harm to the experimental animals. Summary of the invention

[0006] In view of the problems existing in the prior art, the present invention provides a multifunctional rodent simulation training device, which integrates multiple simulation functions such as tracheal intubation, gavage, intraperitoneal injection and tail vein injection, aiming to reduce the waste of resources in experiments and improve the operation standards and proficiency of teaching and scientific research. The device can provide comprehensive simulation training in different operation scenarios by accurately restoring the key anatomical structures of rodents, realize repeated practice of multiple operations, and help scientific researchers and students improve their operation standards and operation skills without live rodents.

[0007] The present invention is achieved in that a multifunctional rodent simulation training device comprises:

[0008] Head structure, trachea and lung structure, esophagus and stomach structure, trunk structure, limb structure, abdominal injection port, tail structure, tail vein injection port;

[0009] A trunk structure is arranged at the top of the tail structure; a lung structure is arranged in the front 1 / 3 of the trunk structure, and a stomach structure is arranged in the center; and a head structure is arranged at the top of the trunk structure.

[0010] Furthermore, the head structure is provided with a trachea and an esophagus; on the surface of the trunk structure, an intraperitoneal injection port is provided on each side 1 cm away from the midline of the abdomen along a line connecting the roots of the hind limbs.

[0011] Furthermore, tail vein injection ports are provided at the distal end, the central end and the proximal end of the tail structure surface.

[0012] The present invention also provides an operating method of a multifunctional rodent simulation training device for anatomical teaching, comprising the following steps:

[0013] Perform tracheal intubation, insert the cannula needle into the trachea through the glottis, retrieve the guide wire, connect the catheter with the ventilator tube, adjust the ventilator parameters such as gas flow, frequency and pressure, and control lung breathing activity. Perform gavage, connect the gavage needle to the injection tube, insert the gavage needle through the mouth into the esophagus until the stomach tube, and inject the liquid in the injection tube into the stomach;

[0014] The head is dissected to identify the relative positions of the trachea and esophagus, and the head structure is cut open to reveal the internal trachea 2 and esophagus 4.

[0015] Further comprising the steps of:

[0016] Perform dissection operations on the torso structure, and cut through the simulated skin and muscles on the outside of the torso to display the internal lung and stomach structures for further anatomical teaching.

[0017] Further, the following steps are included:

[0018] The drug was injected into the simulated mouse peritoneal cavity through an intraperitoneal injection port located on the surface of the trunk structure, on the left and right sides of the line connecting the roots of the hind limbs 1 cm away from the midline of the abdomen;

[0019] Tail vein injection or simulated blood sampling is performed through the tail vein injection port on the tail structure, and the tail vein injection port is located at the distal end, the middle end and the proximal end of the tail structure.

[0020] In combination with the above technical solutions and the technical problems solved, the advantages and positive effects of the technical solutions to be protected by the present invention are as follows:

[0021] First, the present invention provides a multifunctional rodent simulation training device, which can effectively solve the problem of waste of resources and potential harm to experimental animals in traditional teaching. The device integrates multiple functions such as tracheal intubation, gavage, intraperitoneal injection and tail vein injection, allowing researchers to perform multiple operation exercises on one device, significantly improving teaching efficiency, while reducing the use of experimental animals, and complying with modern experimental ethics standards.

[0022] Traditionally, researchers need to use a large number of experimental mice to master these operations. However, with the simulation device of the present invention, researchers can repeatedly practice the operations, become familiar with each step, and reduce the use of experimental animals. This not only greatly reduces the waste of resources, but also improves the level of animal welfare, and makes the practice process more flexible without relying on a dedicated experimental site.

[0023] The design of this device is a detailed reproduction of the anatomical structure of mice. For example, when practicing tracheal intubation, the device simulates the tongue and glottis structure of mice to ensure the authenticity of the operation. In the tail vein injection function, the dorsal vein is designed as a positioning mark, and the left and right veins are the best injection points. When the injection is successful, the liquid will flow out from the vein at the top of the tail; if the injection does not enter the vein but mistakenly enters the surrounding tissue, the special surrounding tissue material will swell slightly to simulate tissue swelling, and then the material will gradually return to its original state as the water evaporates.

[0024] In terms of the intraperitoneal injection function, the device simulates the actual situation of the abdominal viscera of mice in an abacus-like arrangement. When practicing intraperitoneal injection, the device also simulates the changes in the body position of mice in real experiments, that is, when the abdomen of the mouse is facing up and the head is slightly lower, the organs are moved closer to the head due to gravity to prevent the needle tip from piercing the organs or injecting liquid into the organs. In addition, the device is designed with protective devices on both sides of the chest cavity to prevent the simulated organs from falling off. The tail, head and body of the device are all detachable, and provide transparent or removable visualization options to more intuitively observe and confirm the operation effect.

[0025] Through the use of this device, researchers can gain real operating experience in a non-living environment, reduce the use of experimental animals, optimize the experimental teaching process, and improve operating standards and proficiency.

[0026] Second, the present invention has achieved significant technical progress, which is specifically reflected in the following aspects:

[0027] 1) Multifunctional integration: The present invention integrates multiple parts such as the head structure, trachea and lung structure, esophagus and stomach structure, trunk structure, limb structure, abdominal cavity injection port, tail structure and tail vein injection port to form a multifunctional rodent simulation training device. This design enables the device to simulate a variety of rodent experimental operations, such as tracheal intubation, gavage, abdominal cavity injection and tail vein injection, thereby meeting a wider range of training needs.

[0028] 2) Improve the efficiency of practice: Since the device integrates multiple functions, researchers can practice multiple operations on one simulation device without changing different simulation equipment. The simulation device can also be split into the head, torso and tail, allowing multiple researchers to practice different operations on the simulation device at the same time. This not only saves time, but also improves the consistency and efficiency of practice.

[0029] 3) Enhanced simulation authenticity: The present invention makes the simulation device closer to real mice in appearance and use experience by carefully designing the structure and position of each component. This highly realistic simulation environment helps scientific researchers better adapt to actual operations and improve their skills.

[0030] 4) Promote skill improvement: Through repeated practice on the multifunctional simulation device, researchers can master various mouse experimental operation techniques more proficiently. This helps them to operate live mice skillfully and accurately in actual operations and improve animal welfare.

[0031] In summary, the multifunctional rodent simulation training device provided by the embodiment of the present invention has achieved significant technological progress by integrating multiple functions, improving training efficiency, enhancing simulation authenticity and promoting skill improvement, and has broad market application prospects.

[0032] Third, the technical solution of the present invention has significant expected benefits and commercial value. For a laboratory or research group, the purchase and use of the device only requires a one-time investment, and the device can be reused until it can no longer be used, and the cost is relatively fixed. Traditional experimental live mouse exercises require continuous investment, including the purchase of experimental mice and feeding costs for each exercise. The cost continues to rise with the number of exercises and the number of people, and there is no upper limit. Therefore, the device will significantly reduce the training costs of scientific researchers and bring higher economic benefits.

[0033] There is no similar simulation device on the market that is specifically used for experimental rodent operation practice. Traditional scientific research operations can only rely on live experimental rodents, which not only consumes a lot of resources, but also requires special laboratory facilities and environments. The emergence of this device provides an alternative for researchers, filling the gap in the field of rodent experimental operation simulation practice, and is highly innovative.

[0034] In addition, the present invention solves a technical problem that researchers have long been eager to solve. In the past, researchers could only practice operations in specific places such as animal rooms, and they had to prepare experimental mice and venues in advance, which limited the flexibility and convenience of the operation. The simulation device of the present invention allows researchers to practice operations at any time in conventional environments such as molecular biology laboratories and teaching and research rooms, reducing dependence on time, venues and resources. This groundbreaking design overcomes the limitations of traditional methods and enables researchers to conduct efficient training without being restricted by time and place. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 It is a top view of the structure of the multifunctional rodent simulation training device provided by an embodiment of the present invention.

[0036] Figure 2 It is a cross-sectional view of the tail structure in the multifunctional rodent simulation training device provided by an embodiment of the present invention.

[0037] In the figure: 1. Head structure; 2. Trachea; 3. Lung structure; 4. Esophagus; 5. Stomach structure; 6. Trunk structure; 7. Limb structure; 8. Intraperitoneal injection port; 9. Tail structure; 10. Tail vein injection port. DETAILED DESCRIPTION

[0038] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0039] In view of the shortcomings of the existing teaching equipment for rodent dissection and injection practice, the present invention proposes a multifunctional rodent simulation practice device, which aims to solve the problems of single function, unrealistic structure, and incomplete operation experience of traditional teaching models. The simulation devices in the prior art usually only have partial functions and cannot fully simulate the anatomical structure and various operation requirements of rodents, which makes it difficult for students to master key technologies in actual operations and the teaching effect is limited. Through comprehensive design, the present invention integrates multiple operation functions such as rodent dissection and injection into one device, thereby improving the comprehensiveness and practicality of teaching.

[0040] The multifunctional rodent simulation training device of the present invention innovatively integrates simulation structures of multiple key parts such as the trachea, lungs, stomach, and tail vein, so that a variety of experimental operation training for animal medicine teaching and scientific researchers can be completed on one device, such as tracheal intubation, gavage, intraperitoneal injection, and tail vein injection. This integrated design not only greatly improves teaching efficiency, but also reduces the use of animals in experiments, which meets the standards of modern experimental ethics.

[0041] In teaching applications, the present invention enables students to repeatedly practice key techniques, such as endotracheal intubation, intragastric injection, dissection, etc., by accurately simulating the anatomical structure and operation process of mice. This highly simulated design improves students' operational standards and proficiency, and shortens the adaptation time from simulation training to real experiments. At the same time, since the device can be reused, it also reduces the use of live animals, helps protect animal welfare, and meets modern teaching and experimental ethical standards.

[0042] The present invention has achieved significant technical progress in industrial applications, which is specifically manifested in the improvement of teaching efficiency and the reduction of teaching costs. By adopting this multifunctional simulation practice device, the experimental teaching process is more efficient and controllable, and teachers can better guide students to perform complex operation training. Compared with traditional teaching methods, this device can not only improve students' operating standards and proficiency, but also reduce the use of animals, and has obvious animal welfare protection and economic benefits. In summary, the present invention has important technical value and broad application prospects in the field of rodent anatomy and injection teaching.

[0043] The following are two specific embodiments for illustrating the practical application scenarios of the multifunctional rodent simulation training device of the present invention:

[0044] Example 1: Simulation exercise of rat gavage operation

[0045] In animal experiments, gavage is a common technique, and students need to master how to accurately deliver drugs or solutions into the stomach of mice through a gavage needle. Traditional teaching methods usually use live mice for practice, but this poses certain operational risks.

[0046] Steps:

[0047] 1. Equipment preparation: The gavage operation is to grasp the skin on the back of the mouse's neck with one hand and fix the mouse, and insert the gavage needle into the mouse's esophagus through the mouth and finally into the stomach with the other hand.

[0048] 2. Gavage simulation: Connect the gavage needle to the injection tube, and the student inserts the gavage needle through the oral cavity of the simulation device. The needle passes through the simulated esophagus and enters the stomach structure.

[0049] 3. Liquid injection: Students slowly push the liquid in the syringe and understand the process of liquid entering the stomach by observing the liquid flow path inside the device.

[0050] 4. Process feedback: The device is designed with a sensor that can emit a prompt sound when the liquid is correctly injected into the stomach, helping students confirm whether the operation is correct. Students can practice repeatedly until they are proficient in the gavage operation.

[0051] Through this embodiment, students can repeatedly practice gavage without using live animals, master the operating skills, and reduce experimental errors.

[0052] Example 2: Simulation exercise of tail vein injection

[0053] Tail vein injection is a commonly used drug administration method in experimental animal research. However, since the tail vein is small and hidden, it is often difficult for beginners to operate accurately, which can easily cause blood vessel rupture or drug extravasation.

[0054] Steps:

[0055] 1. Device preparation: Place the tail structure of the multifunctional rodent simulation training device in an easy-to-operate position, confirm that the tail vein injection port is in an open state, use the dorsal vein as a positioning mark, and the left and right veins as the best injection points.

[0056] 2. Injection simulation: Students use the needle to align with the tail vein injection port set on the surface of the tail structure, and gently press the needle to insert the needle into the simulated tail vein. It should be noted that the needle must accurately enter the left and right veins to ensure the injection effect.

[0057] 3. Drug injection: The simulated drug (such as dyed water) in the injection tube enters the tail vein through the needle. When the needle enters the vein correctly, the liquid will flow out from the vein at the top of the tail, indicating that the injection is successful. If the needle does not enter the vein correctly, but enters the surrounding tissue by mistake, the special tissue material in the device will simulate tissue swelling and change color to indicate that the needle has not entered the vein, and gradually return to its original state.

[0058] 4. Correction practice: If students fail to inject correctly and observe tissue swelling and discoloration, they need to adjust the needle angle and depth and re-inject until the liquid flows out from the top of the vein, indicating a successful operation. This embodiment allows students to repeatedly practice tail vein injection in a safe environment, improve accuracy and confidence in operation, and lay a solid foundation for actual experimental operation.

[0059] These two embodiments demonstrate the application scenarios of the multifunctional rodent simulation training device of the present invention, which helps students to perform highly simulated experimental technology exercises under non-living conditions, greatly improving the teaching effect and the success rate of experimental operations.

[0060] like Figure 1 As shown, a multifunctional rodent simulation training device provided by an embodiment of the present invention comprises:

[0061] Head structure 1, trachea 2 and lung structure 3, esophagus 4 and stomach structure 5, trunk structure 6, limb structure 7, abdominal injection port 8, tail structure 9, tail vein injection port 10;

[0062] A trunk structure 6 is arranged at the top of the tail structure 9; a lung structure 3 is arranged in the front 1 / 3 of the trunk structure 6, and a stomach structure 5 is arranged in the center; and a head structure 1 is arranged at the top of the trunk structure 6.

[0063] The head structure 1 is provided with a trachea 2 and an esophagus 4; on the surface of the trunk structure 6, an intraperitoneal injection port 8 is provided on each side of the line connecting the roots of the hind limbs, 1 cm away from the midline of the abdomen.

[0064] The tail structure 9 is provided with tail vein injection ports 10 at the distal end, the center and the proximal end thereof.

[0065] The detailed working principle of the present invention:

[0066] 1) Tail structure 9

[0067] The tail structure 9 is a part that simulates the tail of a mouse, and is mainly used to simulate the scene of tail vein injection of a mouse. A tail vein injection port 10 is arranged in the center of the surface of the tail structure 9. The injection port is designed to be a reusable and highly simulated structure, allowing researchers to practice injections multiple times and experience the real injection feeling.

[0068] 2) Trunk structure 6

[0069] The trunk structure 6 is the core part of the whole simulation device, simulating the body of a mouse. The design of the trunk structure 6 takes into account anatomical accuracy in order to provide a more realistic experimental experience.

[0070] 3) Stomach structure 5

[0071] The stomach structure 5 is located in the center of the trunk structure 6, simulating the stomach of a mouse. By performing operations on the stomach structure 5, intragastric operations, such as drug injection, etc., can be simulated.

[0072] 4) Endotracheal intubation

[0073] The endotracheal tube is arranged in the head structure 1 to simulate the endotracheal tube operation. The structural design allows researchers to practice endotracheal tube intubation to improve the operation standard and proficiency in actual operation.

[0074] 5) Header structure 1

[0075] The head structure 1 simulates the head of a mouse, including the nasal cavity, oral cavity and trachea. The head structure 1 is provided with a tracheal cannula so that the tracheal cannula operation can be practiced in this part.

[0076] 6) Intraperitoneal injection port 8

[0077] The intraperitoneal injection port 8 is arranged on the upper left side of the surface of the trunk structure 6 to simulate the intraperitoneal injection scene of mice. Researchers can practice intraperitoneal injection through the injection port and experience the real injection feeling.

[0078] 7) Tail vein injection port 10

[0079] The tail vein injection port 10 is arranged at the center of the surface of the tail structure 9 to simulate the tail vein injection of mice. The injection port is designed to be a highly simulated structure, making the injection practice closer to the actual operation.

[0080] Working principle:

[0081] 1) Simulated injection operation: Through the tail vein injection port 10 and the abdominal cavity injection port 8, researchers can practice different types of injection operations, including tail vein injection and abdominal cavity injection. These injection ports are designed to be reusable and highly simulated, providing a realistic injection experience.

[0082] 2) Simulated endotracheal intubation operation: The endotracheal tube is set in the head structure 1, trachea 2 and lung structure 3. Researchers can practice endotracheal intubation through the above structures and experience the difficulty and skill requirements in actual operation.

[0083] 3) Simulated gavage operation: The esophagus 4 and the stomach structure 5 allow researchers to practice gavage operation, simulating the operation scene in the actual experiment.

[0084] 4) Overall coordination: The trunk structure 6 connects the head structure 1 and the tail structure 9 to form a complete simulation device. The structural design of each part is reasonable and coordinated with each other, making the overall operation more coherent and realistic.

[0085] Through this multifunctional rodent simulation training device, scientific researchers can conduct a variety of operation exercises in the laboratory, improve their experimental skills and operational proficiency, and provide effective training and preparation for actual experiments.

[0086] The multifunctional rodent simulation training device involved in the present invention is intended to effectively solve the problem of resource waste in traditional training methods. Specifically, traditionally, in order to master relevant operating skills, individuals need to practice with a large number of experimental animals, which is not only costly but also inconsistent with the principle of efficient use of resources. However, this device provides a highly simulated simulation practice environment, allowing users to master basic operating methods and processes in advance without consuming life, greatly improving the welfare level of experimental animals.

[0087] The advantage of this simulation training device is that it allows users to be more standardized and skilled in operating on live experimental mice in actual applications after becoming familiar with the simulation operation, thereby significantly reducing resource waste and improving animal welfare. In addition, the use of this device is not restricted by location, and users can practice anytime and anywhere according to their own needs. Compared with the traditional training method that must use live experimental mice in a specific place, this device provides higher flexibility and convenience.

[0088] In summary, the multifunctional mouse simulation exercise device of the present invention reduces the dependence on experimental live mice through simulation exercises, which not only reduces the training cost, but also improves the welfare level of experimental animals, as well as the flexibility and efficiency of training, and at the same time helps to cultivate the user's operating skills and reduce the waste of resources in actual operation. The key components of the simulation training model, such as the tongue and throat structure of the mouse, must be as realistic as possible; three veins should be set in the superficial layer of the tail to truly simulate the tail vein structure, so as to achieve key operations such as positioning and injection; and a simulated response should be given according to the operation results of the trainer, such as when the injection fails, the liquid will infiltrate around the tail vein, and when the injection is successful, the liquid will flow out from the top of the tail vein. In the abdominal cavity, the internal organs should be arranged in a simulated state. When the mouse is flat, the internal organs are evenly distributed in the abdominal cavity and are easily damaged during the intraperitoneal injection process; when the mouse abdomen is upward and the head is low, the internal organs will be close to the chest due to gravity, which is convenient for intraperitoneal injection operation. The tail, head and trunk of the model should be designed as a detachable structure for easy operation and observation. To improve the visualization effect, the exterior of the model should be made of transparent materials, or designed with a removable skin to facilitate observation of the internal structure. The overall material of the model has not yet been determined.

[0089] Example 1: Multifunctional rodent simulation training device for anatomy teaching

[0090] Device composition:

[0091] Head structure 1: simulates the head structure of a mouse, including a simulated nasal cavity, oral cavity, and internal trachea 2 and esophagus 4 connected thereto. This structure is used to simulate the head anatomy and tracheal intubation operation of mice in teaching.

[0092] Trachea 2 and lung structure 3: The trachea 2 is connected to the lung structure 3, which is located in the front 1 / 3 of the trunk structure 6. The lung structure 3 can simulate the breathing process by pumping gas from the outside to show the state of lung expansion and contraction.

[0093] The esophagus 4 and the stomach structure 5: the esophagus 4 is connected to the stomach structure 5 located in the center of the trunk, simulating the digestive tract structure of mice, which is convenient for teaching and practicing gavage operations. The injection tube is connected with a gavage needle, and the gavage needle is inserted from the mouth into the esophagus to the stomach tube, and then the liquid in the injection tube is injected into the stomach.

[0094] Trunk structure 6: the main trunk structure, which contains the lung structure 3 and the stomach structure 5, and is covered with simulated skin on the outside, so that anatomical incision practice can be performed.

[0095] Limb structure 7: The limb structure is used to simulate the limbs of mice, which is convenient for practicing injection and other operations.

[0096] Intraperitoneal injection port 8: It is arranged on the surface of the trunk structure 6, located on the left and right sides of the line connecting the roots of the hind limbs 1 cm away from the midline of the abdomen, simulating the intraperitoneal injection site of real mice for students to practice intraperitoneal injection techniques.

[0097] Tail structure 9: connected to the tail of the trunk structure 6, with tail vein injection ports 10 respectively arranged at the distal end, the center and the proximal end of the surface for practicing tail vein injection techniques.

[0098] Application scenarios:

[0099] This device is mainly used for laboratory teaching, allowing students to practice anatomical operations, tracheal intubation, intraperitoneal injections, and tail vein injections. Through the simulation structure and materials, students can master experimental operation skills in a realistic environment.

[0100] Example 2: Multifunctional rodent simulation training device for pharmacological experiments

[0101] Device composition:

[0102] Head structure 1: including simulated trachea 2 and esophagus 4, the head is detachable, which is convenient for simulating tracheal intubation and drug gavage experiments on mice.

[0103] Trachea 2 and lung structure 3: The trachea 2 is connected to the internal lung structure 3, and the lung structure 3 simulates the anatomical structure of the lungs of real mice and can simulate breathing after tracheal intubation.

[0104] Esophagus 4 and stomach structure 5: The esophagus 4 is connected to the stomach structure 5, and the stomach structure 5 is arranged in the center of the trunk structure 6 for simulating the experimental operation of intragastric drug administration.

[0105] Trunk structure 6: It has built-in lung and stomach structures, and its exterior simulates real mouse skin and muscles, allowing for experimental operations such as drug gavage, subcutaneous injection, and intradermal injection.

[0106] Limb structure 7: simulates the limbs of mice and can be used to simulate experimental operations such as subcutaneous injection.

[0107] Intraperitoneal injection port 8: It is arranged on the surface of the trunk structure 6, and one injection port is arranged on the left and right of the line connecting the roots of the hind limbs 1 cm away from the midline of the abdomen, so as to facilitate the practice of intraperitoneal injection of drugs.

[0108] Tail structure 9: simulates the tail of a mouse, with tail vein injection ports 10 respectively arranged at the distal, central and proximal ends of the tail surface for practicing tail vein injection and blood sampling operations.

[0109] Application scenarios:

[0110] The device is suitable for pharmacology experimental teaching, helping students master the drug administration operations commonly used in rodent experiments. Through the simulation structure, students can repeatedly practice various experimental operations, master the drug administration routes and operation techniques, reduce the number of experimental animals, and improve experimental operation standards and proficiency.

[0111] The above description is only a specific implementation mode of the present invention, but the protection scope of the present invention is not limited thereto. Any modifications, equivalent substitutions and improvements made by any technician familiar with the technical field within the technical scope disclosed by the present invention and within the spirit and principle of the present invention should be covered by the protection scope of the present invention.

Claims

1. A multifunctional rodent simulation training device, characterized in that: The multifunctional rodent simulation training device comprises: Head structure, trachea and lung structure, esophagus and stomach structure, trunk structure, limb structure, abdominal injection port, tail structure, tail vein injection port; A trunk structure is arranged at the top of the tail structure; a lung structure is arranged in the front 1 / 3 of the trunk structure, and a stomach structure is arranged in the center; and a head structure is arranged at the top of the trunk structure.

2. The multifunctional rodent simulation training device according to claim 1, characterized in that: The head structure is provided with a trachea and an esophagus; on the surface of the trunk structure, an intraperitoneal injection port is provided on each side 1 cm away from the abdominal midline on the line connecting the roots of the hind limbs.

3. The multifunctional rodent simulation training device as claimed in claim 1, characterized in that: A peritoneal injection port is respectively arranged on the upper left side and the upper right side of the trunk structure surface.

4. The multifunctional rodent simulation training device according to claim 1, characterized in that: Tail vein injection ports are respectively arranged at the distal end, the central end and the proximal end of the tail structure surface.

5. An operating method of a multifunctional rodent simulation training device for anatomical teaching, characterized in that: The following steps are involved: The head structure is connected to the trunk structure, a simulated tracheal tube is inserted through the trachea in the head structure, and the lung structure is inflated by an external air pump to simulate the breathing process of mice; Perform gavage operation, connect the gavage needle to the injection tube, insert the gavage pillow from the mouth into the esophagus until the stomach tube, and then inject the liquid in the injection tube into the stomach; Perform head dissection to identify the relative position of the trachea and esophagus and display the internal trachea and esophagus by cutting open the head structures.

6. The method for operating the multifunctional rodent simulation training device for anatomical teaching according to claim 6, characterized in that: The following steps are involved: Perform dissection operations on the torso structure, and cut through the simulated skin and muscles on the outside of the torso to display the internal lung and stomach structures for further anatomical teaching.

7. A method for operating a multifunctional rodent simulation training device for pharmacological experiments, comprising the following steps: The drug was injected into the simulated mouse peritoneal cavity through an intraperitoneal injection port located on the surface of the trunk structure, on the left and right sides of the line connecting the roots of the hind limbs 1 cm away from the midline of the abdomen; Tail vein injection or simulated blood sampling is performed through the tail vein injection port on the tail structure, and the tail vein injection port is located at the distal end, the middle end and the proximal end of the tail structure.

8. The method for operating the multifunctional rodent simulation training device for pharmacological experiments according to claim 7, characterized in that: The following steps are involved: The head structure was removed, and the trachea was inserted and connected to the lung structure to perform tracheal intubation, which was then inflated by an external air pump to observe the expansion and contraction of the lung structure to simulate the breathing process of mice.

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