Integrated organic synthesis console

Abstract

The invention relates to the technical field of experimental equipment, in particular to an integrated organic synthesis console which comprises a console body, and a multi-channel embedded temperature controller and an embedded stirring speed regulator are arranged on the console body; a plurality of groups of stirrers and heaters which are equal to the stirrers in number and are in one-to-one correspondence with the stirrers are arranged in the console body, and the temperature controller is connected with the plurality of groups of heaters and used for simultaneously monitoring and controlling the plurality of groups of heaters; the stirring speed regulator is connected with the plurality of groups of stirrers and is used for simultaneously monitoring and controlling the plurality of groups of stirrers; meanwhile, a nitrogen input module, a vacuum input module and a cooling water input module are further integrated on the console body, nitrogen, vacuum and cooling water can be provided at the same time during an experiment, a plurality of modules which are not related originally are integrated in an integration mode, reaction control under different scenes is achieved, and the organic synthesis experiment efficiency is greatly improved.

Description

Technical Field

[0001] The invention relates to the technical field of experimental equipment, in particular to an integrated organic synthesis console. Background Art

[0002] At present, in organic synthesis laboratories, common synthesis reactions require the use of temperature control, magnetic stirring, nitrogen, vacuum, water cooling and other operating methods. Temperature control mainly uses oil bath heating, and the common method is a heat-collecting magnetic stirrer, which integrates heating and magnetic stirring together; another temperature control method is to use a temperature controller + transformer, and at the same time put the oil bath on the magnetic stirrer to achieve the purpose of heating and stirring. These are the two common temperature control and magnetic stirring methods in laboratories; nitrogen and vacuum are provided by nitrogen cylinders and vacuum pumps respectively, and water cooling is directly connected to tap water.

[0003] For the heat-collecting magnetic stirrer, although the integration of temperature control and magnetic stirring is realized and the volume is reduced, the temperature control method can only adopt the relay method, that is, the temperature control accuracy is not high, especially when the voltage is unstable or the voltage increases at the trough at night, it is easy to cause the oil bath temperature to fluctuate greatly, especially for low temperatures such as room temperature and 37°C and when precise control is required, the temperature cannot be accurately controlled. In addition, the oil bath of the heat-collecting magnetic stirrer is fixed. When heating and stirring reaction bottles of different specifications, it is necessary to replace heat-collecting magnetic stirrers of different specifications, which is not very applicable. In addition, the combination of temperature controller + transformer + magnetic stirrer can solve the voltage problem to a certain extent (the heating voltage is lowered by transformer or voltage regulator to reduce the influence of voltage on temperature control accuracy), but a set of heating and stirring system requires three instruments, which occupies a large area and is inconvenient to use, especially when multiple parallel reactions need to be thrown at the same time; in addition, there are generally more corrosive gases and solvents in chemical laboratories, which have a greater impact on transformers, especially when voltage regulators are prone to produce electric sparks when regulating voltage, which is a huge safety hazard in laboratories.

[0004] At the same time, no matter which of the above-mentioned heating and stirring methods is used, it is impossible to directly use nitrogen, vacuum, cooling water and other operations, and additional docking is required, which also makes the operation in the synthesis process cumbersome.

[0005] Based on this, this scheme provides an integrated organic synthesis console, which not only realizes the integration of temperature control and stirring, but also integrates functions such as nitrogen, vacuum, cooling water, etc. on the console, while basically taking up no operating space, and fully realizing the integration of operations commonly used in the field of organic synthesis. Summary of the invention

[0006] The present invention aims to at least solve the problem in the prior art that multiple functions need to be highly integrated in an organic synthesis experiment.

[0007] The present invention provides an integrated organic synthesis console, which is achieved by the following specific technical means: comprising a console body, on which a plurality of embedded temperature controllers and embedded stirring speed regulators are arranged; a plurality of stirrers and heaters equal in number to and corresponding to the stirrers are arranged in the console body, the temperature controller is connected to the plurality of heaters to simultaneously monitor and control the plurality of heaters; and the stirring speed regulator is connected to the plurality of stirrers to simultaneously monitor and control the plurality of stirrers;

[0008] At the same time, the console body is also integrated with a nitrogen input module, a vacuum input module and a cooling water input module, which can provide nitrogen, vacuum and cooling water at the same time during the experiment.

[0009] Preferred technical solution 1: A console front panel is arranged on the front side of the console body, and the control panels of the temperature controller and the speed regulator are also arranged on the console front panel; a main power switch is also arranged on the console front panel.

[0010] Preferred technical solution 2: The vacuum input module includes a vacuum input port and a vacuum supply interface arranged on the right side panel of the console body, the vacuum input port is externally connected to a vacuum pump or other vacuum generator, and the vacuum input module also includes a filtration vacuum interface arranged on the right side panel of the console body; the vacuum input module also includes a vacuum pump speed regulator connected to the vacuum pump;

[0011] The cooling water input module includes a cooling water input port and a cooling water supply interface arranged on the right side panel of the console body, and the cooling water input port is externally connected to a tap water pipeline; the cooling water input module also includes a micro peristaltic pump and a peristaltic pump speed regulator arranged on the right side panel of the console body, the micro peristaltic pump is connected to the cooling water input port and the cooling water supply interface, and the peristaltic pump speed regulator is used to control the speed of the micro peristaltic pump;

[0012] The nitrogen input module includes a nitrogen input port and a nitrogen supply interface arranged on the right side panel of the console body, and the nitrogen input port is externally connected to a nitrogen cylinder; the nitrogen input module also includes a positive pressure fine-tuning valve connected to the nitrogen supply interface;

[0013] At the same time, an equipment operation timer is installed on the right side panel, which is connected to the micro peristaltic pump and the vacuum pump to control their working time.

[0014] Preferred technical solution three: A cooling fan is provided on the rear side panel of the console body to dissipate heat from the console body; at the same time, a vacuum pressure gauge connection port, a communication port, and an AC220V power input port are also provided on the rear side panel.

[0015] Preferred technical solution 4: The left panel of the console body is provided with multiple groups of temperature sensor input sockets, multiple groups of temperature control heating power output sockets, and multiple groups of signal lights;

[0016] The temperature sensor input socket is used to connect the temperature sensor of the oil bath pot. At the same time, the group plugs the power supply of the oil bath pot heating ring into the corresponding temperature control heating power output socket, and the heating temperature of the oil bath pot can be fed back through the temperature sensor; at the same time, the temperature control heating power output socket is connected to the temperature controller.

[0017] Preferred technical solution five: The front panel is also provided with a multi-way temperature control switch, a stirring control switch, a speed switch, a nitrogen control switch, a vacuum control switch, a cooling water control switch, a timer, etc.

[0018] Preferred technical solution six: the upper panel of the console body is a flat plate, and a number of rods are installed on the rear side of the upper panel as fixing devices, and different numbers of oil bath pots are placed according to needs; each group of oil bath pots is placed on a corresponding group of agitators.

[0019] Preferred technical solution seven: The console body is in the shape of a rectangular parallelepiped and can be customized according to the experimental site.

[0020] The above structure enables this solution to have the following beneficial effects:

[0021] 1. Through equipment integration, multi-channel temperature control, magnetic stirring control, nitrogen vacuum control, and cooling water control can be achieved on one device. All operating modules are carried out inside the console, which can reduce the corrosion of each module in the chemical synthesis corrosive environment, extend the service life, and increase the safety during use. (Currently, the company has designed and manufactured 7 devices, all of which have been running stably for more than 2,000 hours);

[0022] 2. Through equipment integration, the laboratory space is used to the maximum extent (each fume hood or glove box can carry out more than 4 reactions at the same time), thus improving the utilization rate of laboratory space;

[0023] 3. The system integrates multiple previously unrelated modules to achieve reaction control in different scenarios, greatly improving the efficiency of organic synthesis experiments. By using oil baths of different sizes (oil baths of different sizes can be used at the same time and are easy to replace), it can meet almost all constant, trace and semi-trace reaction specifications.

[0024] 4. By connecting to the host computer through RS485 communication, automatic control of temperature and stirring, as well as networking control between multiple devices can be achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0026] Figure 1 This is the main view of this scheme;

[0027] Figure 2 This is the rear view of this scheme;

[0028] Figure 3 This is the left view of this scheme;

[0029] Figure 4 This is the right view of this scheme;

[0030] Figure 5 This is a top view of this scheme.

[0031] Among them, 1. console body, 11. front panel, 111. temperature control switch, 112. timer, 113. main power switch, 114. temperature controller, 115. stirring speed regulator, 12. upper panel, 121. stirrer, 122. rod, 13. right side panel, 131. vacuum input port, 132. vacuum supply interface, 133. filtration vacuum interface, 134. cooling water input port, 135. cooling water supply interface, 136. micro peristaltic pump, 137. Peristaltic pump speed regulator, 138, vacuum pump speed regulator, 139, nitrogen supply interface, 1310, positive pressure fine-tuning valve, 1311, equipment operation timer, 14, rear panel, 141, cooling fan, 142, vacuum pressure gauge connection port, 143, communication port, 144, AC220V power input port, 145, insurance and indicator light, 15, left panel, 151, temperature sensor input socket, 152, temperature control heating power output socket, 153, signal light. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0033] See also Figure 1 and Figure 5 , an integrated organic synthesis console, comprising a console body 1, on which a multi-channel embedded temperature controller 114 (adopting the existing technology) and an embedded stirring speed regulator 115 (adopting the existing technology) are arranged, wherein the temperature controller 114 serves as a main controller;

[0034] The console body 1 is provided with a plurality of groups of stirrers 121 (using the existing technology) and heaters (using the existing technology) equal in number and corresponding to the stirrers 121. The stirrers 121 and heaters are preferably provided with 4-10 groups, and 4-10 parallel reactions (oil bath and stirring) can be carried out simultaneously. A group of heaters is combined with a group of stirrers 121, such as the electric heating plate in the heater is installed on the top surface of the stirrer 121. The upper panel 12 of the console body 1 is a flat plate, and a plurality of stainless steel or iron rods 122 are installed on the rear side of the upper panel 12 as a fixing device. At the same time, different numbers of oil bath pots are placed according to needs; each group of oil bath pots is placed on a corresponding group of stirrers 121;

[0035] The temperature controller 114 is connected to the multiple sets of heaters for simultaneously monitoring and controlling the multiple sets of heaters; the stirring speed regulator 115 is connected to the multiple sets of stirrers 121 for simultaneously monitoring and controlling the multiple sets of stirrers 121;

[0036] At the same time, the console body 1 is also integrated with a nitrogen input module, a vacuum input module and a cooling water input module, which can provide nitrogen, vacuum and cooling water at the same time during the experiment;

[0037] The temperature controller 114 and the control panel of the speed regulator are arranged on the front panel 11 of the console body 1. The front panel 11 of the console is also provided with a main power switch 113, which is used to switch on and off the circuit system in the console body 1 and the power supply.

[0038] The stirrer 121 is preferably a magnetic stirrer.

[0039] See also Figure 4 , an integrated organic synthesis console, a vacuum input module includes a vacuum input port 131 and a vacuum supply interface 132 arranged on the right side panel 13 of the console body 1, the vacuum input port 131 is externally connected to a vacuum pump or other vacuum generator, and the vacuum supply interface 132 is communicated with the vacuum input port 131; at the same time, the vacuum input module also includes a filtration vacuum interface 133 arranged on the right side panel 13 of the console body 1, and the filtration vacuum interface 133 is also communicated with the vacuum input port 131; the vacuum input module also includes a vacuum pump speed regulator 138 (using the existing technology) connected to the vacuum pump, and the vacuum pump speed regulator 138 is used to control the speed of the vacuum pump;

[0040] The cooling water input module includes a cooling water input port 134 and a cooling water supply interface 135 arranged on the right side panel 13 of the console body 1. The cooling water input port 134 is externally connected to a tap water pipeline, and the cooling water supply interface 135 is used to discharge the tap water entering the cooling water input port 134; the cooling water input module also includes a micro peristaltic pump 136 and a peristaltic pump speed regulator 137 (using the existing technology) arranged on the right side panel 13 of the console body 1. The micro peristaltic pump 136 is connected to the cooling water input port 134 and the cooling water supply interface 135, and the peristaltic pump speed regulator 137 is used to control the rotation speed of the micro peristaltic pump 136, thereby controlling the supply amount of cooling water;

[0041] The nitrogen input module includes a nitrogen input port and a nitrogen supply interface 139 provided on the right side panel 13 of the console body 1. The nitrogen input port is externally connected to a nitrogen cylinder, and the nitrogen in the nitrogen cylinder is directly connected to the nitrogen supply interface 139. The nitrogen input module also includes a positive pressure fine-tuning valve 1310 connected to the nitrogen supply interface 139 for accurately adjusting the nitrogen flow rate.

[0042] At the same time, a device operation timer 1311 is also installed on the right side panel 13, which is connected to the micro peristaltic pump 136 and the vacuum pump to control their working time;

[0043] The centralized supply of nitrogen, vacuum and cooling water is realized on the console body 1 .

[0044] See also Figure 2 , an integrated organic synthesis console, a plurality of cooling fans 141 are arranged on the rear side panel 14 of the console body 1 for cooling the console body 1;

[0045] At the same time, the rear side panel 14 is also provided with a vacuum pressure gauge connection port 142, a communication port 143, and an AC220V power input port 144;

[0046] The vacuum pressure gauge connection port 142 is used to connect a vacuum pressure gauge to monitor the vacuum pressure value in the vacuum supply interface 132;

[0047] Communication port 143 is used to access other devices and exchange data between devices. Communication port 143 is preferably an RS485 communication port, such as communicating with a host computer to achieve networking of multiple devices and automatic temperature control;

[0048] The AC220V power input port 144 is used to connect the power supply to the circuit system in the console body 1;

[0049] The rear panel 14 is also provided with a fuse and an indicator light 145 , which are connected to the circuit system.

[0050] See also Figure 3, an integrated organic synthesis console, the left panel 15 of the console body 1 is provided with a plurality of groups of temperature sensor input sockets 151, a plurality of groups of temperature control heating power output sockets 152, and a plurality of groups of signal lights 153;

[0051] The temperature sensor input socket 151 is used to connect the temperature sensor of the oil bath pot. At the same time, the group plugs the power supply of the oil bath pot heating coil into the corresponding temperature control heating power supply output socket 152, and the heating temperature of the oil bath pot can be fed back through the temperature sensor; at the same time, the temperature control heating power supply output socket 152 is connected to the temperature controller 114;

[0052] The signal light 153 is connected to the corresponding temperature-controlled heating power output socket 152 for displaying the working status.

[0053] See also Figure 1 , an integrated organic synthesis console, the front panel 11 is also provided with a multi-way temperature control switch 111, a stirring control switch, a speed switch, a nitrogen control switch, a vacuum control switch, a cooling water control switch, a timer 112, etc.;

[0054] The timer 112 is connected to the plurality of stirrers 121 and is used to set the stirring time;

[0055] A plurality of groups of temperature control switches 111 are respectively connected to corresponding heaters to control the switches of the heaters;

[0056] A plurality of stirring control switches are respectively connected to corresponding stirrers 121, and are used to control the switches of the stirrers 121;

[0057] The speed switch is connected to the corresponding stirring speed regulator 115 and is used to control the switch of the stirring speed regulator 115;

[0058] The nitrogen control switch is connected to the nitrogen supply interface 139 and is used to control the switch of the nitrogen supply interface 139;

[0059] A plurality of vacuum control switches are connected to the corresponding vacuum supply interface 132 and the filtration vacuum interface 133, and are used to control the switches of the vacuum supply interface 132 and the filtration vacuum interface 133;

[0060] The cooling water control switch is connected to the cooling water supply interface 135 and is used to control the switch of the cooling water supply interface 135;

[0061] All control units are concentrated on the front panel 11, which facilitates the control of reaction conditions and greatly improves the reaction efficiency;

[0062] The instrument adopts an integrated approach to integrate conventional operations such as temperature control, magnetic stirring, nitrogen supply, vacuum supply, cooling water supply, etc. commonly used in organic synthesis into one instrument, which can realize multi-channel temperature control, multi-channel magnetic stirring, nitrogen vacuum supply, cooling water supply and communication control.

[0063] See also Figure 1-Figure 5 , integrated organic synthesis console, the console body 1 is in the shape of a rectangular parallelepiped, which can be customized according to the experimental site, and can be integrated with commonly used fume hoods, glove boxes, etc., and basically does not occupy additional countertops, fume hood countertops or glove box countertops;

[0064] The height of the console body 1 is between 100-200mm according to the requirements, and the width and depth can be customized according to the use site. The general width is 1000-1800mm (the net width of a general fume hood or glove box), and the depth is 400-750mm (the net depth of a general fume hood or glove box);

[0065] It saves experimental operation space, enables multiple reactions to be carried out simultaneously (especially for parallel reactions that require the same nitrogen, vacuum, stirring or temperature control for easy control), improves the operating efficiency of single-step or multi-step reactions, and improves the level of automation control of the equipment.

[0066] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An integrated organic synthesis console, comprising a console body (1), characterized in that: The console body (1) is provided with a multi-channel embedded temperature controller (114) and an embedded stirring speed regulator (115); The console body (1) is provided with a plurality of groups of stirrers (121) and heaters having the same number and corresponding to the stirrers (121), and the temperature controller (114) is connected to the plurality of groups of heaters; At the same time, the stirring speed regulator (115) is connected to multiple groups of stirrers (121); At the same time, a nitrogen input module, a vacuum input module and a cooling water input module are also integrated on the console body (1).

2. An integrated organic synthesis console according to claim 1, characterized in that: A front panel (11) is arranged on the front side of the console body (1), and the temperature controller (114) and the control panel of the speed regulator are also arranged on the front panel (11).

3. An integrated organic synthesis console according to claim 2, characterized in that: The vacuum input module comprises a vacuum input port (131) and a vacuum supply interface (132) arranged on the right side panel (13) of the console body (1); the vacuum input port (131) is externally connected to a vacuum pump or other vacuum generator, and the vacuum supply interface (132) is in communication with the vacuum input port (131); the vacuum input module also comprises a filtration vacuum interface (133) arranged on the right side panel (13) of the console body (1), and the filtration vacuum interface (133) is in communication with the vacuum input port (131); the vacuum input module also comprises a vacuum pump speed regulator (138) connected to the vacuum pump.

4. An integrated organic synthesis console according to claim 3, characterized in that: The cooling water input module comprises a cooling water input port (134) and a cooling water supply interface (135) arranged on the right side panel (13) of the console body (1); the cooling water input port (134) is externally connected to a tap water pipeline, and the cooling water supply interface (135) is used to discharge the tap water entering the cooling water input port (134); the cooling water input module also comprises a micro peristaltic pump (136) and a peristaltic pump speed regulator (137) arranged on the right side panel (13) of the console body (1); the micro peristaltic pump (136) is connected to the cooling water input port (134) and the cooling water supply interface (135), and the peristaltic pump speed regulator (137) is used to control the rotation speed of the micro peristaltic pump (136).

5. An integrated organic synthesis console according to claim 4, characterized in that: The nitrogen input module comprises a nitrogen input port and a nitrogen supply interface (139) arranged on the right side panel (13) of the console body (1); the nitrogen input port is externally connected to a nitrogen cylinder, and the nitrogen in the nitrogen cylinder is directly connected to the nitrogen supply interface (139); the nitrogen input module also comprises a positive pressure fine-tuning valve (1310) connected to the nitrogen supply interface (139); The right side panel (13) is also provided with a device operation timer (1311), which is connected to the micro peristaltic pump (136) and the vacuum pump.

6. An integrated organic synthesis console according to claim 5, characterized in that: The rear side panel (14) of the console body (1) is provided with a cooling fan (141), a vacuum pressure gauge connection port (142), a communication port (143), an AC220V power input port (144), and a fuse and indicator light (145).

7. An integrated organic synthesis console according to claim 2, characterized in that: The left panel (15) of the console body (1) is provided with a plurality of groups of temperature sensor input sockets (151), a plurality of groups of temperature-controlled heating power output sockets (152), and a plurality of groups of signal lights (153).

8. The integrated organic synthesis console according to claim 5, characterized in that: The front panel (11) is also provided with a main power switch (113), a timer (112), a temperature control switch (111), a stirring control switch, a speed switch, a nitrogen control switch, a vacuum control switch, and a cooling water control switch.

9. The integrated organic synthesis console according to claim 1, characterized in that: The upper panel (12) of the console body (1) is a flat plate, and a plurality of stainless steel or iron rods (122) are installed on the rear side of the upper panel (12) as fixing devices, and different numbers of oil bath pots are placed according to needs; each group of oil bath pots is placed on a corresponding group of stirrers (121).

10. The integrated organic synthesis console according to claim 1, characterized in that: The console body (1) is in the shape of a rectangular parallelepiped and can be integrated with a commonly used fume hood or glove box.

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