Rotor spacing adjustable structure based on rotating flow focusing

Abstract

The invention discloses a rotor spacing adjustable structure based on rotary flow focusing, and relates to the technical field of microfluidics. The device comprises a supporting frame, the supporting frame is rotationally connected with a plurality of rotor shafts, the rotor shafts are connected with rotors, the rotors are of a circular truncated cone structure, and any two adjacent rotors are arranged in an up-and-down reversing mode and used for adjusting the width of a slit between the two adjacent rotors by adjusting the axial positions of the rotors. By adjusting the axial positions of the rotors, the width of a slit between every two adjacent rotors can be adjusted, so that adjustment can be carried out flexibly according to the size of a needle head or the size of micro-droplets needing to be prepared, and the overall use flexibility and adaptability are effectively improved; the multiple rotors are arranged side by side, and the different slit widths of the rotors are adjusted, so that the droplet preparation device can prepare micro-droplets with different particle sizes at the same time, and the overall preparation efficiency is greatly improved.

Description

Technical Field

[0001] The invention belongs to the field of microfluidic technology, and in particular relates to a rotor spacing adjustable structure based on rotational flow focusing. Background Art

[0002] Microdroplets are tiny droplets with micro-nano size, involving many types of materials and structures, and are extremely widely used. They have important application value in many fields such as biomedicine, energy and environment. In these practical applications, the preparation and molding of droplets usually involve complex conditions such as high temperature, and place high demands on the particle size, yield, uniformity, surface morphology, etc. of the droplets.

[0003] Traditional methods for preparing microdroplets include emulsification, microfluidics and flow focusing. The emulsification method is simple to operate and has high efficiency, but the droplet uniformity is poor, the repeatability between batches is low, and the material application range is narrow. The droplets prepared by the microfluidics method have good uniformity and high repeatability, but the preparation efficiency is low and it also has the defect of a narrow material application range. Flow focusing technology is difficult to apply to high-viscosity fluids due to the limitation of pipeline size.

[0004] For example, Chinese invention CN111569965A discloses an open nanometer-scale droplet preparation device and method based on a symmetrical rotor, which uses a symmetrical rotor to drive the surrounding continuous phase fluid to form a focusing effect at the slit, so that the dispersed phase flowing out of the capillary needle forms a jet and eventually breaks into droplets.

[0005] However, in this method, the rotors rotate through gears, so that the spacing between the rotors cannot be flexibly adjusted, and thus cannot be flexibly adjusted according to the size of the needle or the particle size of the microdroplets to be prepared, resulting in poor overall flexibility and adaptability. Summary of the invention

[0006] The object of the present invention is to provide a rotor spacing adjustable structure based on rotating flow focusing. The rotor is formed into a truncated cone structure, and any two adjacent rotors are arranged upside down relative to each other. By adjusting the axial position of the rotor, the slit width between the two adjacent rotors can be adjusted, thereby solving the problem that the spacing between the existing rotors cannot be flexibly adjusted and the overall flexibility and adaptability of use are poor.

[0007] In order to solve the above technical problems, the present invention is achieved through the following technical solutions:

[0008] The present invention is a rotor spacing adjustable structure based on rotational flow focusing, comprising a support frame, the support frame is rotatably connected to a plurality of rotor shafts, the plurality of rotor shafts are all connected to rotors, the rotors are in a truncated cone structure, and any two adjacent rotors are arranged upside down relative to each other, so as to adjust the slit width between two adjacent rotors by adjusting the axial position of the rotors.

[0009] As a preferred technical solution of the present invention, the upper ends of several of the rotor shafts are rotatably connected to support sleeves, the outer wall of the support sleeves is provided with external threads and is threadedly connected to the support frame, so as to adjust the axial position of the rotor by rotating the support sleeves.

[0010] As a preferred technical solution of the present invention, a flange is provided at the upper end of the support sleeve, and a set screw is threadedly connected to the flange for fixing the support sleeve through the set screw.

[0011] As a preferred technical solution of the present invention, the circumferential surface of the flange is provided with anti-slip grooves.

[0012] As a preferred technical solution of the present invention, the number of the rotor shafts is two or more. When the number of the rotor shafts is greater than two, the axial position of the rotors is adjusted so that the rotors have different slit widths, thereby achieving simultaneous preparation of micro-droplets of different particle sizes.

[0013] The present invention has the following beneficial effects:

[0014] The present invention forms a truncated cone structure for the rotors, and sets any two adjacent rotors upside down relative to each other. By adjusting the axial positions of the rotors, the slit width between the two adjacent rotors can be adjusted, so that the slit width can be flexibly adjusted according to the size of the needle or the size of the micro-droplets to be prepared, thereby effectively improving the overall flexibility and adaptability of use.

[0015] At the same time, by arranging multiple rotors side by side and adjusting the axial position of the rotors, the rotors can have different slit widths. Slits of different widths can adapt to needles of different sizes and prepare micro-droplets of different particle sizes. Therefore, the droplet preparation device can prepare micro-droplets of different particle sizes at the same time, greatly improving the overall preparation efficiency.

[0016] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0018] Figure 1 It is a structural schematic diagram of the rotor spacing adjustable structure based on rotational flow focusing of the present invention;

[0019] Figure 2 It is a schematic diagram of the structure of the frame, the supporting sleeve and the rotor shaft;

[0020] Figure 3 for Figure 2 A front view of

[0021] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0022] 1-support frame, 2-rotor shaft, 3-rotor, 4-support sleeve, 5-needle head, 401-flange, 402-set screw. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] In the description of the present invention, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inside", "all around" and the like indicating orientation or positional relationship are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the components or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0025] See also Figures 1 to 3 As shown, the present invention is a rotor spacing adjustable structure based on rotational flow focusing, including a support frame 1, the support frame 1 is rotatably connected to a plurality of rotor shafts 2, the plurality of rotor shafts 2 are all connected to a rotor 3, the number of rotor shafts 2 is two or more, and the support frame 1 can adopt the support frame structure in the prior art. The rotor shafts 2 are arranged side by side, and are driven by gear meshing with each other. A drive motor is installed on the support frame 1, and the drive motor drives the rotor shafts 2 to rotate through gear transmission. The drive motor is not shown in the figure, and the specific installation method in the prior art can be referred to.

[0026] The rotor 3 is a truncated cone structure, and any two adjacent rotors 3 are arranged upside down relative to each other, so that the slit width between the two adjacent rotors 3 can be adjusted by adjusting the axial position of the rotor 3, so that it can be flexibly adjusted according to the size of the needle or the size of the micro-droplets to be prepared, effectively improving the overall flexibility and adaptability of use.

[0027] And, if Figure 1 As shown, when the number of rotor shafts 2 is greater than two, such as four as shown in the figure, four rotors 3 are arranged side by side to form three slits, and the end of the needle 5 is located in the slit. By adjusting the axial position of one or two rotors 3, the rotors 3 have different slit widths with each other, so that needles 5 of different sizes can be accommodated at the same time, and micro-droplets of different particle sizes can be prepared, so that the droplet preparation device can prepare micro-droplets of different particle sizes at the same time, greatly improving the overall preparation efficiency.

[0028] The upper end of each rotor shaft 2 is rotatably connected to a support sleeve 4. The rotor shaft 2 and the support sleeve 4 are axially rotatably connected and their axial positions are limited, for example, by installing a retaining spring.

[0029] The outer wall of the support sleeve 4 is provided with an external thread, and a threaded hole is provided on the horizontal plate of the support frame 1, so that the support sleeve 4 is threadedly connected to the support frame 1, which is used to rotate the support sleeve 4 to make the support sleeve 4 move in the axial position, thereby driving the rotor shaft 2 to move axially, and then realizing the adjustment of the axial position of the rotor 3.

[0030] The upper end of the support sleeve 4 is provided with a flange 401, and the circumferential surface of the flange 401 is provided with anti-slip grooves, so that the support sleeve 4 can be rotated manually through the flange 401. At the same time, the flange 401 is provided with a threaded hole, and a set screw 402 is threadedly connected. The lower end of the set screw 402 is abutted against the horizontal plate of the support frame 1, and the support sleeve 4 is fixed by the set screw 402 to prevent the support sleeve 4 from rotating unexpectedly, which may cause the axial position of the rotor 3 to change, so that the overall stability and reliability of use can be guaranteed by the set screw 402.

[0031] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0032] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A rotor spacing adjustable structure based on rotational flow focusing, comprising a support frame (1), the support frame (1) being rotatably connected to a plurality of rotor shafts (2), the plurality of rotor shafts (2) being all connected to a rotor (3), characterized in that: The rotor (3) is in a truncated cone structure, and any two adjacent rotors (3) are arranged upside down relative to each other, so as to adjust the slit width between the two adjacent rotors (3) by adjusting the axial position of the rotor (3).

2. The rotor spacing adjustable structure based on rotational flow focusing according to claim 1, characterized in that: The upper ends of the plurality of rotor shafts (2) are rotatably connected to support sleeves (4), the outer wall of the support sleeves (4) is provided with external threads and is threadedly connected to the support frame (1), so as to adjust the axial position of the rotor (3) by rotating the support sleeves (4).

3. The rotor spacing adjustable structure based on rotational flow focusing according to claim 2 is characterized in that: The upper end of the support sleeve (4) is provided with a flange (401), and the flange (401) is threadedly connected with a set screw (402) for fixing the support sleeve (4) via the set screw (402).

4. The rotor spacing adjustable structure based on rotational flow focusing according to claim 3 is characterized in that: The circumferential surface of the flange (401) is provided with anti-slip grooves.

5. The rotor spacing adjustable structure based on rotational flow focusing according to claim 1, 2, 3 or 4, characterized in that: The number of the rotor shafts (2) is two or more. When the number of the rotor shafts (2) is greater than two, the axial positions of the rotors (3) are adjusted so that the rotors (3) have different slit widths, thereby achieving simultaneous preparation of micro-droplets of different particle sizes.

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