Multi-channel nucleic acid amplification detection device and color development method

Abstract

The multichannel nucleic acid amplification detection device comprises a shell, a heating reaction device is arranged in the shell, the heating reaction device comprises a flow guide cover, the outer wall of the top of the flow guide cover is communicated with a sample inlet, and the outer wall of the bottom of the flow guide cover is fixedly connected with a flow dividing cavity; a sealing gasket is arranged at the bottom of the inner wall of the flow dividing cavity, and a reaction plate is arranged on the outer wall of the bottom of the flow dividing cavity. A sample liquid is added into a heating reaction device internally provided with a reaction reagent, the sample liquid is added through a sample inlet in a flow guide cover and enters a flow dividing cavity for liquid separation, the sample liquid is averagely divided into a plurality of parts and sent to corresponding reaction tank cavities, and the sample liquid is uniformly distributed into a plurality of different fluid channels through the upper layer of the flow dividing cavity; and the lower layer is used for guiding the sample liquid into a chromogenic reaction layer in the reaction plate from a liquid outlet of the vertical channel.

Description

Technical Field

[0001] The present invention belongs to the field of medical detection technology, and in particular relates to a multi-channel nucleic acid amplification detection device and a color development method. Background Art

[0002] Nucleic acid amplification testing is a method of amplifying the nucleic acid sequence to be tested through the action of enzymes and then detecting it. It mainly includes polymerase chain reaction (PCR), loop-mediated isothermal amplification reaction (LAMP), recombinase polymerase amplification (RPA), etc.

[0003] Traditional nucleic acid amplification detection methods require steps such as polymerase chain reaction, agarose gel electrophoresis, and fluorescence detection and interpretation, which requires a lot of equipment and time. At the same time, various types of luminescence or color change reaction detections have many disadvantages, such as high difficulty in operation, complex procedures, high detection thresholds, and cannot be applied to instant detection of sample chemical analysis or biochemical analysis in various occasions. Summary of the invention

[0004] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a multi-channel nucleic acid amplification detection device and a color development method, which have the advantage of being easy to use.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a multi-channel nucleic acid amplification detection device, comprising a shell, a heating reaction device is arranged inside the shell, the heating reaction device comprises a guide cover, the top outer wall of the guide cover is connected to the sample inlet, the bottom outer wall of the guide cover is fixedly connected with a diversion chamber, a sealing gasket is arranged at the bottom of the inner wall of the diversion chamber, a reaction plate is arranged on the bottom outer wall of the diversion chamber, a reaction pool chamber is opened on the inner wall of the reaction plate, a reaction reagent is arranged on the inner wall of the reaction pool chamber, a connecting plate is fixedly connected to the bottom outer wall of the reaction plate, a heating plate is fixedly connected to the bottom outer wall of the connecting plate, the outer wall of the heating plate, a light guide column is arranged on the top of the heating plate, and a slot is fixedly connected to the outer wall of the heating plate.

[0006] Preferably, the reaction structure of the reaction pool cavity includes a color development reaction layer, the color development reaction layer includes two symmetrical light path entrances, the top of the light path entrance is provided with a first reflection surface, the inner wall of the light path entrance is connected to the reaction chamber, the outer wall of the reaction chamber is fixedly connected with a second reflection surface, the inner wall of the light path entrance is fixedly connected with a central penetration point, the detection light source, the bottom of the light path entrance is provided with a detection light source, and the bottom of the central penetration point is provided with sensor 2 and sensor 1.

[0007] Preferably, the bottom of the entrance of the light path can also be set as sensor 1, and the bottom of the central transparent point can also be set as a detection light source.

[0008] Preferably, a cover plate is provided on the outer wall of the shell, and a button is fixedly connected to the outer wall of the cover plate.

[0009] Preferably, a display screen is fixedly connected to the outer wall of the shell, and a switch is fixedly connected to the outer wall of the shell.

[0010] Preferably, the outer wall of the shell is provided with a power interface, and the outer wall of the shell is fixedly connected with a signal interface.

[0011] A multi-channel nucleic acid amplification detection color development method comprises the following steps:

[0012] S1. Add the sample liquid into the heating reaction device with built-in reaction reagents, wherein the sample liquid is added through the sample inlet on the guide cover and enters the diversion chamber for liquid separation, and the sample liquid is evenly divided into several parts and sent to the corresponding reaction pool chamber, wherein the upper layer of the diversion chamber evenly distributes the sample liquid into several different fluid channels, and the lower layer introduces the sample liquid from the liquid outlet of the vertical channel into the color reaction layer in the reaction plate, and the sealing gasket is used to seal the diversion chamber and the reaction plate to ensure that the sample liquid enters the color reaction layer from each fluid channel of the diversion chamber of the liquid separation structure, and then the cover is opened by pressing the button, and the heating reaction device is placed in it. The reaction plate and the heating plate are directly contacted and heated through the slots, and the heating plate is connected to the main control circuit for communication to complete the temperature management and signal of the equipment. Processing, result interpretation, information display and information transmission, etc., are also used to complete the signal processing and function realization of all modules. After the cover is closed, the detection starts according to the set parameters. The sample liquid and the reaction reagent undergo subsequent chemical reactions. The heating plate uses an aluminum plate as a heat sink to adjust the reaction temperature. The reaction pool cavity is used to receive the final external sample for reaction. The light guide column on the connecting plate plays a role. Through the internal light path, the external light source is guided to enter and illuminate the sample liquid in the reaction, and finally the light is led out to the color sensor unit for detection. The color sensor unit identifies the visible light or fluorescence changes caused by the chemical reaction or biochemical reaction process of each channel reaction chamber to achieve the result identification of the chemical analysis process. The positive result can be read in thirty to sixty minutes.

[0013] S2. The detection light source is placed below the entrance of the light path. The entrance of the light path usually has a convex structure with a bunching structure. A first reflecting surface is arranged above the entrance of the light path. The first reflecting surface can reflect the incident light from the direction from bottom to top to the direction from left to right or from right to left. The light enters from one side of the reaction chamber and emerges from the other side. It is irradiated to the second reflecting surface of the entrance of the light path. Through the reflection effect of the second reflecting surface, it is irradiated to the central penetration point position, and finally the sensor measurement is performed by the second color sensor unit;

[0014] S3. The positions of the detection light source and sensor 1 can be changed, which makes the detection method more flexible and applicable to more detection scenarios;

[0015] S4. The cover can be closed by pressing the upper cover button, and the display screen can facilitate human-computer interaction;

[0016] S5. After the power interface is connected to the power supply, the switch can be used to turn the machine on and off;

[0017] S6. The power interface can be connected to the power supply to provide power for the device, and the signal interface can facilitate data interaction.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] 1. Add the sample liquid into the heating reaction device with built-in reaction reagents, wherein the sample liquid is added through the sample inlet on the guide cover and enters the diversion chamber for liquid separation, and the sample liquid is evenly divided into several parts and sent to the corresponding reaction pool chamber, wherein the upper layer of the diversion chamber evenly distributes the sample liquid into several different fluid channels, and the lower layer introduces the sample liquid from the liquid outlet of the vertical channel into the color reaction layer in the reaction plate, and the sealing gasket is used to seal the diversion chamber and the reaction plate to ensure that the sample liquid enters the color reaction layer from each fluid channel of the diversion chamber of the liquid separation structure, and then the cover is opened by the button, and the heating reaction device is placed in it. The reaction plate and the heating plate are directly contacted and heated through the slots, and the heating plate is connected to the main control circuit for communication to complete the temperature management and signal processing of the equipment. It has functions such as processing, result interpretation, information display and information transmission. It is also used to complete the signal processing and function realization of all modules. After the cover is closed, the detection starts according to the set parameters. The sample liquid and the reaction reagent undergo subsequent chemical reactions. The heating plate uses an aluminum plate as a heat sink to adjust the reaction temperature. The reaction pool cavity is used to receive the final external sample for reaction. The light guide column on the connecting plate plays a role. Through the internal light path, it guides the external light source to enter and illuminate the sample liquid in the reaction, and finally leads the light to the colorimetric sensing unit for detection. The colorimetric sensing unit identifies the visible light or fluorescence changes caused by the chemical reaction or biochemical reaction process in the reaction chamber of each channel to achieve the result identification of the chemical analysis process. A positive result can be read out in thirty to sixty minutes.

[0020] 2. When the detection light source is placed below the entrance of the light path of the color reaction layer, the incident light is reflected from the bottom to the top to the left to the right or the right to the left by relying on the reflection surface above the entrance of the light path, so that the light enters from one side of the reaction chamber and emerges from the other side, and shines on the exit reflection surface of the light path, and then through the reflection effect of the reflection surface, shines on the exit center point position, and finally is sensed and measured by the sensor of the color sensing unit.

[0021] 3. The color reaction layer is provided with reaction chambers for color reaction. These chambers are arranged according to certain rules, usually distributed around a center point, and can be regular polygons formed by a circular arrangement, or can be an axisymmetric rectangular structure; accordingly, the inner and outer sides of the reaction chambers of the implemented color reaction layer are provided with light path conduction structures, and the center of the area formed by these reaction chambers is a hollow structure. When light is irradiated from the outside to the light path conduction structure on the outside of the reaction chamber and passes through the reaction hole, it is irradiated to the surrounding center point through the light path conduction structure. By constructing the detection logic formed by the detection lamp, the reaction chamber, the color sensor, the main control unit and the result display unit, it is conducive to the qualitative or quantitative analysis of the reaction process and the rapid and intuitive output of the detection results. By detecting that the light source emits visible light and irradiates it into a transparent solution, the light passes through the solution to absorb light or other color changes, and the optical signal generated is received by the sensor and transmitted to the main control unit. The main control unit controls the result display unit to display the reaction detection result according to the detection result. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the main structure of the present invention;

[0023] Figure 2 It is a schematic diagram of the main top structure of the present invention;

[0024] Figure 3 It is a structural schematic diagram of the back side of the main body of the present invention;

[0025] Figure 4 This is a schematic diagram of the color development reaction layer of the present invention having two light sources;

[0026] Figure 5 The color development reaction layer of the present invention has a light source structure schematic diagram.

[0027] In the figure: 1. shell; 2. cover plate; 3. button; 4. display screen; 5. switch; 6. power interface; 7. signal interface; 8. light guide column; 9. slot; 100. heating reaction device; 200. flow guide cover; 201. injection port; 203. color reaction layer; 300. diversion chamber; 301. sensor 1; 304. sensor 2; 400. reaction reagent; 500. sealing gasket; 600. reaction plate; 602. reaction pool chamber; 603. connecting plate; 700. heating plate; 20311. detection light source; 20312. light path entrance; 20313. first reflection surface; 20314. reaction chamber; 20315. second reflection surface; 20316. center penetration point. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] Embodiment 1:

[0030] See also Figure 1-Figure 5 The present invention provides a technical solution: a multi-channel nucleic acid amplification detection device, comprising a shell 1, a heating reaction device 100 is arranged inside the shell 1, the heating reaction device 100 comprises a guide cover 200, the top outer wall of the guide cover 200 is connected with an injection port 201, the bottom outer wall of the guide cover 200 is fixedly connected with a shunt chamber 300, a sealing gasket 500 is arranged at the bottom of the inner wall of the shunt chamber 300, a reaction plate 600 is arranged on the bottom outer wall of the shunt chamber 300, a reaction pool chamber 602 is opened on the inner wall of the reaction plate 600, a reaction reagent 400 is arranged on the inner wall of the reaction pool chamber 602, a connecting plate 603 is fixedly connected to the bottom outer wall of the reaction plate 600, a heating plate 700 is fixedly connected to the bottom outer wall of the connecting plate 603, the outer wall of the heating plate 700, the top of the heating plate 700 is provided with a light guide column 8, and the outer wall of the heating plate 700 is fixedly connected with a slot 9.

[0031] In this embodiment, the sample liquid is added to the heating reaction device 100 with the reaction reagent 400 built in, wherein the sample liquid is added through the sample inlet 201 on the guide cover 200, enters the diversion chamber 300 for liquid separation, and evenly divides the sample liquid into several parts, and sends it to the corresponding reaction pool chamber 602, wherein the upper layer of the diversion chamber 300 evenly distributes the sample liquid into several different fluid channels, and the lower layer introduces the sample liquid from the liquid outlet of the vertical channel into the color reaction layer 203 in the reaction plate 600, and the sealing gasket 500 is used to seal the diversion chamber 300 and the reaction plate 600 to ensure that the sample liquid enters the color reaction layer 203 from each fluid channel of the diversion chamber 300 of the liquid separation structure, and then the cover plate 2 is opened by the button 3, and the heating reaction device 100 is placed therein, and the reaction plate 600 is directly contacted and heated with the heating plate 700 through the slot 9, and the heating plate 700 communicates It is connected to the main control circuit to complete the functions of temperature management, signal processing, result interpretation, information display and information transmission of the equipment. It is also used to complete the signal processing and function realization of all modules. After the cover plate 2 is covered, the detection is started according to the set parameters. The sample liquid and the reaction reagent 400 undergo subsequent chemical reactions. The heating plate 700 uses an aluminum plate as a heat sink to adjust the reaction temperature. The reaction pool cavity 602 is used to receive the final external sample for reaction. The light guide column 8 on the connecting plate 603 plays a role. Through the internal light path, the external light source is guided to enter and irradiate the sample liquid in the reaction, and finally the light is led out to the color sensor unit for detection. The color sensor unit identifies the visible light or fluorescence changes caused by the chemical reaction or biochemical reaction process of each channel reaction chamber 20314 to achieve the result identification of the chemical analysis process. A positive result can be read in thirty to sixty minutes.

[0032] Embodiment 2:

[0033] See also Figure 4-Figure 5 On the basis of the first embodiment, the present invention provides a technical solution: the reaction structure of the reaction pool chamber 602 includes a color reaction layer 203, the color reaction layer 203 includes two symmetrical light path entrances 20312, the top of the light path entrance 20312 is provided with a first reflection surface 20313, the inner wall of the light path entrance 20312 is connected to the reaction chamber 20314, the outer wall of the reaction chamber 20314 is fixedly connected with a second reflection surface 20315, the inner wall of the light path entrance 20312 is fixedly connected with a central penetration point 20316 and a detection light source 20311, the bottom of the light path entrance 20312 is provided with a detection light source 20311, the bottom of the central penetration point 20316 is provided with a sensor two 304 and a sensor one 301, the bottom of the light path entrance 20312 can also be set as a sensor 301 one, and the bottom of the central penetration point 20316 can also be set as a detection light source 20311.

[0034] In this embodiment, the light path entrance 20312 usually has a beam-forming convex structure, and a first reflecting surface 20313 is arranged above the light path entrance 20312. The first reflecting surface 20313 can reflect the incident light from the direction from bottom to top to from left to right or from right to left. The light enters from one side of the reaction chamber 20314 and emerges from the other side, and is irradiated onto the second reflecting surface 20315 of the light path entrance 20312. Through the reflection effect of the second reflecting surface 20315, it is irradiated to the center transmission point 20316 position, and finally sensed and measured by the color sensing unit sensor 2 304. The positions of the detection light source 20311 and the sensor 1 301 can be replaced, which can make the detection method more flexible and applicable to more detection scenarios.

[0035] Embodiment three:

[0036] See also Figure 1-Figure 3 On the basis of Embodiment 1 and Embodiment 2, the present invention provides a technical solution: the outer wall of the shell 1 is provided with a cover plate 2, the outer wall on the cover plate 2 is fixedly connected with a button 3, the outer wall of the shell 1 is fixedly connected with a display screen 4, the outer wall of the shell 1 is fixedly connected with a switch 5, the outer wall of the shell 1 is provided with a power interface 6, and the outer wall of the shell 1 is fixedly connected with a signal interface 7.

[0037] In this embodiment, the upper cover button 3 can be used to close the cover 2, and the display screen 4 can facilitate human-computer interaction. After the power interface 6 is connected to the power, the switch 5 can be used to turn the device on and off. The power interface 6 can be connected to the power supply to provide power for the device, and the signal interface 7 can facilitate data interaction.

[0038] The working principle and use process of the present invention are as follows: the sample liquid is added into the heating reaction device 100 with the reaction reagent 400 built in, wherein the sample liquid is added through the sample inlet 201 on the flow guide cover 200, enters the diversion chamber 300 for liquid separation, and the sample liquid is evenly divided into several parts, and sent to the corresponding reaction pool chamber 602, wherein the upper layer of the diversion chamber 300 evenly distributes the sample liquid into several different fluid channels, and the lower layer introduces the sample liquid from the liquid outlet of the vertical channel into the color reaction layer 203 in the reaction plate 600, and the sealing gasket 500 is used to seal the diversion chamber 300 and the reaction plate 600 to ensure that the sample liquid enters the color reaction layer 203 from each fluid channel of the diversion chamber 300 of the liquid separation structure, and then passes through The cover plate 2 is opened by pressing the button 3, and the heating reaction device 100 is placed therein. The reaction plate 600 and the heating plate 700 are directly contacted and heated through the slot 9. The heating plate 700 is connected to the main control circuit for communication, and is used to complete the functions of temperature management, signal processing, result interpretation, information display and information transmission of the equipment, and is also used to complete the signal processing and function realization of all modules. After the cover plate 2 is closed, the detection is started according to the set parameters, and the sample liquid and the reaction reagent 400 undergo subsequent chemical reactions. The heating plate 700 uses an aluminum plate as a heat sink to adjust the reaction temperature. The reaction pool cavity 602 is used to receive the final external sample for reaction. The light guide column 8 on the connecting plate 603 plays a role in guiding the external light source to enter through the internal light path. The light is introduced into and illuminated the sample liquid in the reaction, and finally the light is led out to the colorimetric sensing unit for detection, wherein the colorimetric sensing unit identifies the visible light or fluorescence changes caused by the chemical reaction or biochemical reaction process of each channel reaction chamber 20314 to realize the result identification of the chemical analysis process, and a positive result can be read out in thirty to sixty minutes. The light path entrance 20312 usually has a bunched convex structure, and a first reflecting surface 20313 is arranged above the light path entrance 20312. The first reflecting surface 20313 can reflect the incident light from the direction from bottom to top to from left to right or from right to left. The light enters from one side of the reaction chamber 20314, emerges from the other side, and illuminates the first side of the light path entrance 20312. On the second reflecting surface 20315, through the reflection effect of the second reflecting surface 20315, it irradiates the center penetration point 20316 position, and finally the sensing measurement is carried out through the color sensing unit sensor 2 304. The positions of the detection light source 20311 and the sensor 1 301 can be replaced, which can make the detection method more flexible and applicable to more detection scenarios. The upper cover button 3 can play the effect of closing the cover 2, and the display screen 4 can facilitate human-computer interaction. After the power interface 6 is connected to the power, the switch 5 can play the effect of turning on and off. The power interface 6 can be connected to the power supply to provide power for the device, and the signal interface 7 can facilitate data interaction.

[0039] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A multi-channel nucleic acid amplification detection device, comprising a housing (1), characterized in that: A heating reaction device (100) is arranged inside the housing (1), and the heating reaction device (100) comprises a flow guide cover (200), the top outer wall of the flow guide cover (200) is connected to a sample inlet (201), the bottom outer wall of the flow guide cover (200) is fixedly connected to a flow diversion chamber (300), a sealing gasket (500) is arranged at the bottom of the inner wall of the flow diversion chamber (300), and a reaction plate (600) is arranged on the bottom outer wall of the flow diversion chamber (300), and the reaction plate ( A reaction pool cavity (602) is provided on the inner wall of the reaction pool cavity (602), a reaction reagent (400) is arranged on the inner wall of the reaction pool cavity (602), a connecting plate (603) is fixedly connected to the bottom outer wall of the reaction plate (600), a heating plate (700) is fixedly connected to the bottom outer wall of the connecting plate (603), an outer wall of the heating plate (700), a light guide column (8) is arranged on the top of the heating plate (700), and a slot (9) is fixedly connected to the outer wall of the heating plate (700).

2. A multi-channel nucleic acid amplification detection device according to claim 1, characterized in that: The reaction structure of the reaction pool cavity (602) includes a color development reaction layer (203), and the color development reaction layer (203) includes two symmetrical light path entrances (20312). The top of the light path entrance (20312) is provided with a first reflection surface (20313), the inner wall of the light path entrance (20312) is connected to a reaction chamber (20314), the outer wall of the reaction chamber (20314) is fixedly connected with a second reflection surface (20315), the inner wall of the light path entrance (20312) is fixedly connected with a central penetration point (20316), the detection light source (20311), the bottom of the light path entrance (20312) is provided with a detection light source (20311), and the bottom of the central penetration point (20316) is provided with sensor 2 (304) and sensor 1 (301).

3. A multi-channel nucleic acid amplification detection device according to claim 2, characterized in that: The bottom of the light path entrance (20312) can also be set as sensor 1 (301), and the bottom of the central transparent point (20316) can also be set as a detection light source (20311).

4. A multi-channel nucleic acid amplification detection device according to claim 1, characterized in that: The outer wall of the housing (1) is provided with a cover plate (2), and the outer wall of the cover plate (2) is fixedly connected with a button (3).

5. A multi-channel nucleic acid amplification detection device according to claim 1, characterized in that: A display screen (4) is fixedly connected to the outer wall of the housing (1), and a switch (5) is fixedly connected to the outer wall of the housing (1).

6. A multi-channel nucleic acid amplification detection device according to claim 1, characterized in that: The outer wall of the housing (1) is provided with a power interface (6), and the outer wall of the housing (1) is fixedly connected with a signal interface (7).

7. A multi-channel nucleic acid amplification detection color development method according to claims 1-6, characterized in that: The following steps are involved: S1. Add the sample liquid into the heating reaction device (100) with the reaction reagent (400) built therein, wherein the sample liquid is added through the sample inlet (201) on the flow guide cover (200), enters the flow separation chamber (300) for liquid separation, and divides the sample liquid into several portions, and sends them to the corresponding reaction pool chamber (602), wherein the upper layer of the flow separation chamber (300) evenly distributes the sample liquid into several different fluid channels, and the lower layer distributes the sample liquid from the liquid in the vertical channel The outlet is introduced into the color reaction layer (203) in the reaction plate (600), and the sealing gasket (500) is used to seal the diversion chamber (300) and the reaction plate (600), so as to ensure that the sample liquid enters the color reaction layer (203) from each fluid channel of the diversion chamber (300) of the liquid separation structure, and then the cover plate (2) is opened by the button (3), and the heating reaction device (100) is placed therein, and the reaction plate (600) is directly contacted with the heating plate (700) through the slot hole (9) for heating. Heat, the heating plate (700) is connected to the main control circuit for communication, and is used to complete the functions of temperature management, signal processing, result interpretation, information display and information transmission of the equipment. It is also used to complete the signal processing and function realization of all modules. After the cover plate (2) is covered, the detection starts according to the set parameters. The sample liquid and the reaction reagent (400) undergo subsequent chemical reactions. The heating plate (700) uses an aluminum plate as a heat sink to adjust the reaction temperature. The reaction pool chamber (602) serves as a final external sample for reaction. The light guide column (8) on the connecting plate (603) plays a role in guiding the external light source to enter and illuminate the sample liquid in the reaction through the internal light path, and finally leads the light to the color sensor unit for detection. The color sensor unit identifies the visible light or fluorescence changes caused by the chemical reaction or biochemical reaction process of each channel reaction chamber (20314) to achieve the result identification of the chemical analysis process. A positive result can be read in thirty to sixty minutes; S2, the detection light source (20311) is placed below the light path entrance (20312), the light path entrance (20312) usually has a beam-forming convex structure, and a first reflection surface (20313) is arranged above the light path entrance (20312), and the first reflection surface (20313) can reflect the incident light from the direction from bottom to top to from left to right or from right to left, and the light enters from one side of the reaction chamber (20314), emerges from the other side, and irradiates the second reflection surface (20315) of the light path entrance (20312), and irradiates the center transmission point (20316) through the reflection effect of the second reflection surface (20315), and finally performs sensing measurement through the second color sensor unit sensor (304); S3. The positions of the detection light source (20311) and the sensor 1 (301) can be changed, so that the detection method can be more flexible and applicable to more detection scenarios; S4, the cover button (3) can be used to close the cover (2), and the display screen (4) can facilitate human-computer interaction; S5. After the power interface (6) is connected to the power supply, the switch (5) can be used to turn the machine on and off; S6. The power interface (6) can be connected to the power source to provide power for the device, and the signal interface (7) can facilitate data interaction.

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