Osmanthus essential oil as well as extraction method and application thereof

Abstract

The invention provides sweet-scented osmanthus essential oil and an extraction method and application thereof.The extraction method of the sweet-scented osmanthus essential oil comprises the specific steps that S1, pretreatment is conducted, fresh and impurity-free sweet-scented osmanthus is repeatedly frozen and thawed 2-4 times, vacuum drying is conducted, and pretreated sweet-scented osmanthus is obtained; s2, micronization: putting the pretreated osmanthus fragrans in the S1 into an ultramicro jet mill to obtain osmanthus fragrans ultrafine powder; and S3, adding the osmanthus fragrans ultrafine powder obtained in S2 into an ethanol-isopropanol-ammonium sulfate three-aqueous-phase extraction system, carrying out primary ultrasonic treatment, adding a cosolvent, carrying out secondary ultrasonic treatment, collecting an extracting solution, evaporating to remove the cosolvent, and carrying out vacuum concentration to obtain the osmanthus fragrans essential oil. The extracted osmanthus essential oil is higher in purity and high in yield, and when the extracted osmanthus essential oil serves as an inflammation inhibitor, the extracted osmanthus essential oil has the good TNF-alpha inhibition rate and has the practical application value.

Description

Technical Field

[0001] The invention relates to the field of essential oil extraction, and in particular to osmanthus essential oil and an extraction method and application thereof. Background Art

[0002] Osmanthus fragrans is an evergreen tree or shrub with four-lobed corolla and small shape. It has a significant sweet and fragrant smell and taste. It has been widely used and has a long history as an additive in the field of food processing and is regarded as a traditional famous flower. Because it is rich in polysaccharides, polyphenols, flavonoids, terpenes, pigments and other effective ingredients, osmanthus fragrans and its products have antioxidant, anti-aging, anti-tumor, lipid-lowering, blood pressure-lowering, cough-relieving and phlegm-reducing, halitosis relief, antibacterial and other effects. The ancients named osmanthus fragrans as "the best of all medicines".

[0003] Essential oils, also known as aromatic oils or volatile oils, are obtained from the flowers, stems, leaves, roots and fruits of plants through certain extraction techniques. Essential oils have a complex chemical composition, mainly including hydrocarbons (such as terpenes and sesquiterpenes) and oxygenated hydrocarbons (such as phenols, epoxides, ethers, esters, acids, alcohols and ketones). Essential oils have unique physical and chemical properties, including antibacterial, anti-inflammatory, antiviral, analgesic, anti-tumor, mosquito repellent, penetration promoting, antioxidant, etc. Therefore, essential oils have been widely used in cosmetics, perfumes, spices, food and pharmaceutical industries. Extraction technology plays an important role in the research of essential oils. Different extraction techniques have an important impact on the quality and yield of essential oils.

[0004] At present, the extraction technology of osmanthus essential oil includes steam distillation, supercritical extraction and organic solvent extraction, etc., and the osmanthus raw materials extracted are fresh osmanthus flowers, salted osmanthus and frozen osmanthus, etc. However, steam distillation has a high operating temperature, large energy consumption, and is easy to cause the hydrolysis of some effective ingredients in the essential oil, while causing the decomposition of heat-sensitive compounds, and the extraction rate is low. In addition, the extracted osmanthus essential oil carries moisture, is prone to mildew, and can cause the loss of active ingredients in the osmanthus essential oil, reducing the application value; supercritical extraction has a high cost and is not suitable for large-scale production; organic solvent extraction can cause the quality of osmanthus essential oil to decline, and the purity becomes low. Therefore, how to improve the quality and yield of essential oils, and reduce the cost of the extraction process, has become a problem that has always been faced in the field of osmanthus essential oil extraction technology. Summary of the invention

[0005] In view of this, the present invention provides an osmanthus essential oil and an extraction method and application thereof.

[0006] The technical solution of the present invention is achieved in this way:

[0007] A method for extracting osmanthus essential oil, the specific steps comprising:

[0008] S1, pretreatment: fresh, impurity-free osmanthus is repeatedly frozen and thawed 2-4 times, and vacuum dried to obtain pretreated osmanthus;

[0009] S2, micronization: placing the pretreated osmanthus fragrans in S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus fragrans powder;

[0010] S3, adding the osmanthus ultrafine powder of S2 into an ethanol-isopropanol-ammonium sulfate tri-phase extraction system, performing a first ultrasonic treatment, adding a cosolvent, performing a second ultrasonic treatment, collecting the extract, evaporating to remove the cosolvent, and concentrating under reduced pressure to obtain osmanthus essential oil.

[0011] Furthermore, in step S1, the freeze-thaw is first frozen at -5 to -2°C for 12 to 24 hours, and then thawed naturally at room temperature.

[0012] Furthermore, in step S2, the particle size of the osmanthus ultrafine powder is 1-50 μm.

[0013] Furthermore, in step S3, the solid-liquid ratio of the osmanthus ultrafine powder to the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 1:10-15 g / mL; the concentration of ammonium sulfate in the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 5%-10% w / v, the concentration of ethanol is 50%-70% v / v, and the concentration of isopropanol is 30%-50% v / v.

[0014] Furthermore, in step S3, the first ultrasonic treatment is performed at 20-30 kHz and 40-50° C. for 1-3 h; and the second ultrasonic treatment is performed at 20-30 kHz and 25-35° C. for 30-60 min.

[0015] Furthermore, in step S3, the co-solvent is lactic acid and glycerol in a mass ratio of 1:2-4; the volume ratio of the co-solvent to the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 0.01-0.03:1.

[0016] A sweet osmanthus essential oil is extracted by the extraction method.

[0017] The osmanthus essential oil extracted by the extraction method is used in the preparation of inflammation inhibitor products.

[0018] Furthermore, the concentration of osmanthus essential oil in the product is 1-5wt%.

[0019] Furthermore, the product is a skin care product, including lotion, emulsion, cream, essence, ointment, and facial mask.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] 1. The extraction process of the present invention avoids the problems of sticking to layers and insufficient and uneven cooking caused by direct steaming and extraction of fresh osmanthus. The extracted osmanthus essential oil has higher purity and high yield, and has practical application value. The osmanthus essential oil extracted by the present invention is used as an inflammation inhibitor and has a good TNF-α inhibition rate.

[0022] 2. The present invention repeatedly freezes and thaws fresh and impure osmanthus to loosen the plant cell structure, form finer powder, and increase the release of effective ingredients. After ultrafine grinding of osmanthus, the particle size and structure of the powder can be effectively improved. The surface area and porosity of the ultrafine powder of 1-50 μm are greatly increased, the solubility is improved, and the subsequent extraction efficiency is improved. The ultrafine powder is ultrasonically extracted by a three-phase extraction system to fully and comprehensively extract the active components. A cosolvent of a specific composition is added to fully dissolve the osmanthus essential oil in the cosolvent, the effective ingredients in the essential oil are not hydrolyzed, the essential oil yield is higher, and the cosolvent is removed by evaporation, so that the osmanthus essential oil has a higher purity. DETAILED DESCRIPTION

[0023] In order to better understand the technical content of the present invention, specific embodiments are provided below to further illustrate the present invention.

[0024] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.

[0025] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.

[0026] Example 1

[0027] A method for extracting osmanthus essential oil, the specific steps comprising:

[0028] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -3°C for 18h, then thaw naturally at room temperature, repeat freeze-thaw 3 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0029] S2, micronization: placing the pretreated osmanthus flowers of S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus powder with a particle size of 20±1 μm;

[0030] S3, according to the solid-liquid ratio of 1:13g / mL, the osmanthus ultrafine powder of S2 was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.08g / mL, the concentration of ethanol was 0.474g / mL, and the concentration of isopropanol was 0.314g / mL), and the first ultrasonic (25kHz, 45°C) extraction was carried out for 2h, and a co-solvent (lactic acid and glycerol in a mass ratio of 1:3) was added, and the volume ratio of the co-solvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system was 0.02:1, and then a second ultrasonic (25kHz, 30°C) extraction was carried out for 45min, the extract was collected, the co-solvent was evaporated to remove the co-solvent, and it was concentrated under reduced pressure to obtain osmanthus essential oil.

[0031] Example 2

[0032] A method for extracting osmanthus essential oil, the specific steps comprising:

[0033] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -5°C for 12h, then thaw naturally at room temperature, repeat freeze-thaw twice, and vacuum dry to obtain pretreated sweet osmanthus;

[0034] S2, micronization: placing the pretreated osmanthus flowers of S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus powder with a particle size of 5±1 μm;

[0035] S3, according to the solid-liquid ratio of 1:10g / mL, the osmanthus ultrafine powder of S2 was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.05g / mL, the concentration of ethanol was 0.3945g / mL, and the concentration of isopropanol was 0.2355g / mL), and the first ultrasonic (20kHz, 40°C) extraction was carried out for 1h, and a co-solvent (lactic acid and glycerol in a mass ratio of 1:2) was added, and the volume ratio of the co-solvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system was 0.01:1, and then a second ultrasonic (20kHz, 25°C) extraction was carried out for 30min, the extract was collected, the co-solvent was evaporated to remove the co-solvent, and it was concentrated under reduced pressure to obtain osmanthus essential oil.

[0036] Example 3

[0037] A method for extracting osmanthus essential oil, the specific steps comprising:

[0038] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -2°C for 24h, then thaw naturally at room temperature, repeat freeze-thaw 4 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0039] S2, micronization: placing the pretreated osmanthus flowers of S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus powder with a particle size of 45±1 μm;

[0040] S3, according to the solid-liquid ratio of 1:15g / mL, the osmanthus ultrafine powder of S2 was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.1g / mL, the concentration of ethanol was 0.5523g / mL, and the concentration of isopropanol was 0.3925g / mL), and the first ultrasonic (30kHz, 50°C) extraction was carried out for 3h, and a cosolvent (lactic acid and glycerol in a mass ratio of 1:4) was added, and the volume ratio of the cosolvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system was 0.03:1, and then a second ultrasonic (30kHz, 35°C) extraction was carried out for 60min, the extract was collected, the cosolvent was evaporated to remove the cosolvent, and it was concentrated under reduced pressure to obtain osmanthus essential oil.

[0041] Comparative Example 1

[0042] The difference from Example 1 is that no pretreatment is performed, and the rest is the same as Example 1.

[0043] That is, the extraction method of the osmanthus essential oil of this comparative example, the specific steps include:

[0044] S1, micronization: fresh, pure osmanthus is dried and placed in an ultra-fine airflow pulverizer to obtain osmanthus ultra-fine powder with a particle size of 20±1 μm;

[0045] S2. According to the solid-liquid ratio of 1:13 g / mL, the osmanthus superfine powder is added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate is 0.08 g / mL, the concentration of ethanol is 0.474 g / mL, and the concentration of isopropanol is 0.314 g / mL), and the first ultrasonic (25 kHz, 45 ° C) extraction is performed for 2 hours, and a cosolvent (lactic acid and glycerol in a mass ratio of 1:3) is added, and the volume ratio of the cosolvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system is 0.02:1, and then a second ultrasonic (25 kHz, 30 ° C) extraction is performed for 45 minutes, the extract is collected, the cosolvent is evaporated to remove the cosolvent, and it is concentrated under reduced pressure to obtain osmanthus essential oil.

[0046] Comparative Example 2

[0047] The difference from Example 1 is that the powder is not micronized, and the other parts are the same as Example 1.

[0048] That is, the extraction method of the osmanthus essential oil of this comparative example, the specific steps include:

[0049] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -3°C for 18h, then thaw naturally at room temperature, repeat freeze-thaw 3 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0050] S2. According to the solid-liquid ratio of 1:13 g / mL, the pretreated osmanthus was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.08 g / mL, the concentration of ethanol was 0.474 g / mL, and the concentration of isopropanol was 0.314 g / mL), and the first ultrasonic (25 kHz, 45 ° C) extraction was performed for 2 hours, and a cosolvent (lactic acid and glycerol in a mass ratio of 1:3) was added, and the volume ratio of the cosolvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system was 0.02:1, and then a second ultrasonic (25 kHz, 30 ° C) extraction was performed for 45 minutes, the extract was collected, the cosolvent was evaporated to remove the cosolvent, and it was concentrated under reduced pressure to obtain osmanthus essential oil.

[0051] Comparative Example 3

[0052] The difference from Example 1 is that the pretreated osmanthus is crushed into ordinary powder with a particle size of 250 μm, and the rest is the same as Example 1.

[0053] That is, the extraction method of the osmanthus essential oil of this comparative example, the specific steps include:

[0054] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -3°C for 18h, then thaw naturally at room temperature, repeat freeze-thaw 3 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0055] S2, micronization: crush the pretreated osmanthus flowers prepared in S1, sieve, and collect osmanthus flower powder with a particle size of 250 μm;

[0056] S3. According to the solid-liquid ratio of 1:13 g / mL, the osmanthus powder of S2 was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.08 g / mL, the concentration of ethanol was 0.474 g / mL, and the concentration of isopropanol was 0.314 g / mL), and the first ultrasonic (25 kHz, 45 ° C) extraction was carried out for 2 hours, and a co-solvent (lactic acid and glycerol in a mass ratio of 1:3) was added, and the volume ratio of the co-solvent to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system was 0.02:1, and then a second ultrasonic (25 kHz, 30 ° C) extraction was carried out for 45 minutes, the extract was collected, the co-solvent was evaporated to remove the co-solvent, and it was concentrated under reduced pressure to obtain osmanthus essential oil.

[0057] Comparative Example 4

[0058] The difference from Example 1 is that the ethanol-isopropanol-ammonium sulfate tri-aqueous phase extraction system is replaced with an ethanol solution with a concentration of 60% v / v, and the rest is the same as Example 1.

[0059] That is, the extraction method of the osmanthus essential oil of this comparative example, the specific steps include:

[0060] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -3°C for 18h, then thaw naturally at room temperature, repeat freeze-thaw 3 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0061] S2, micronization: placing the pretreated osmanthus flowers of S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus powder with a particle size of 20±1 μm;

[0062] S3. According to the solid-liquid ratio of 1:13 g / mL, the osmanthus ultrafine powder of S2 was added to an ethanol solution with a concentration of 60% v / v, and the first ultrasonic (25 kHz, 45°C) extraction was carried out for 2 hours, and a co-solvent (lactic acid and glycerol in a mass ratio of 1:3) was added, and the volume ratio of the co-solvent to the ethanol solution with a concentration of 60% v / v was 0.02:1, and then a second ultrasonic (25 kHz, 30°C) extraction was carried out for 45 minutes, the extract was collected, the co-solvent was evaporated to remove the extract, and the extract was concentrated under reduced pressure to obtain osmanthus essential oil.

[0063] Comparative Example 5

[0064] The difference from Example 1 is that no co-solvent is added, and the rest is the same as Example 1.

[0065] That is, the extraction method of the osmanthus essential oil of this comparative example, the specific steps include:

[0066] S1. Pretreatment: freeze-thaw fresh sweet osmanthus without impurities, first freeze at -3°C for 18h, then thaw naturally at room temperature, repeat freeze-thaw 3 times, and vacuum dry to obtain pretreated sweet osmanthus;

[0067] S2, micronization: placing the pretreated osmanthus flowers of S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus powder with a particle size of 20±1 μm;

[0068] S3. According to the solid-liquid ratio of 1:13 g / mL, the osmanthus ultrafine powder of S2 was added to the ethanol-isopropanol-ammonium sulfate tri-phase extraction system (the concentration of ammonium sulfate was 0.08 g / mL, the concentration of ethanol was 0.474 g / mL, and the concentration of isopropanol was 0.314 g / mL), and ultrasonic (25 kHz, 45°C) extraction was performed for 2 h. The extract was collected and concentrated under reduced pressure to obtain osmanthus essential oil.

[0069] 1. Performance test data

[0070] The performance of the osmanthus essential oils prepared by specific processes in Examples 1-3 and Comparative Examples 1-5 was evaluated, and the data results are shown in Table 1.

[0071] The essential oil extraction rate is calculated as follows: essential oil extraction rate = (essential oil mass / fresh osmanthus mass without impurities) × 100%

[0072] Among them, the contents of hexahydroxytaxene and dihydro-β-ionol were determined by GC-MS analysis.

[0073] Chromatographic conditions: the chromatographic column was HP-5MS, a quartz capillary column (30 m×0.25 mm, 0.25 μm), and the carrier gas was high-purity nitrogen.

[0074] Injection method: injection volume is 0.5 μL, split ratio is 5:1, and injection port temperature is 250 °C.

[0075] Temperature program: initial temperature was 60 °C, increased to 280 °C at a rate of 4 °C / min, and maintained for 1 min.

[0076] Mass spectrometry conditions: electron impact (EI) electron source, ion source temperature 230°C, electron energy 70 eV, scanning mass range 30-550 amu.

[0077] Table 1

[0078]

[0079]

[0080] As can be seen from Table 1, compared with Comparative Examples 1-5, the processes of repeated freeze-thaw pretreatment, ultrafine grinding, ultrasonic extraction in the three-phase extraction system and cosolvent are indispensable to improve the extraction rate of osmanthus essential oil.

[0081] 2. Inflammatory factor inhibition experiment

[0082] Study subjects: RAW 264.7 macrophages

[0083] The cellular inflammation model was established by stimulating cells with lipopolysaccharide LPS (bacterial endotoxin), and the osmanthus essential oil (concentration 1%) of Example 1 and 0.5% quercetin were added as the positive control group. The cells were cultured for 24 h, and the cell supernatant was collected. The release level of the pro-inflammatory inflammatory factor TNF-α of RAW 264.7 macrophages was analyzed by ELISA kit. The results are shown in Table 2.

[0084] Table 2

[0085] sample TNF-α inhibition rate / % Example 1 57.8 Positive control group 55.7

[0086] As can be seen from Table 2, the osmanthus essential oil of Example 1 of the present invention has a good TNF-α inhibition rate, has a good anti-inflammatory effect, and can be used as an inflammation inhibitor.

[0087] 3. Irritation test

[0088] With reference to the Technical Specifications for Safety of Cosmetics (2015 edition), a closed patch test was performed behind the ear of the test subject. 0.02 mL of the test substance was dropped into the patch tester, which was then sealed behind the left ear of the test subject with tape. After 30 minutes, the test substance patch tester was removed, the skin reaction was observed, and the score was recorded.

[0089] Among them, skin reaction is a negative reaction, with a score of 0;

[0090] The skin reaction is a suspicious reaction with only slight erythema, and the score is 1;

[0091] Skin reactions include erythema, infiltration, edema, and papules, with a score of 2;

[0092] Skin reactions included erythema, infiltration, edema, and herpes, with a score of 3;

[0093] Skin reactions included obvious erythema, severe infiltration, edema, and confluent herpes, with a score of 4.

[0094] The test results of each group were averaged, and the specific results are shown in Table 3.

[0095] Table 3

[0096] sample Rating scale result Examples 1-3 0 No stimulation

[0097] As can be seen from Table 3, the osmanthus essential oils prepared in Examples 1-3 of the present invention are non-irritating and non-harmful to the skin and are highly safe.

[0098] Application Examples

[0099] The osmanthus essential oil essence comprises the following raw materials, calculated by mass percentage: 3% osmanthus essential oil, 10% 1,3-butylene glycol, 1% triethanolamine, 0.1% p-hydroxyacetophenone, 0.5% disodium ethylenediaminetetraacetate, and the balance water, totaling 100%.

[0100] The preparation method of osmanthus essential oil essence comprises the following specific steps:

[0101] (1) 1,3-butanediol, triethanolamine, p-hydroxyacetophenone and disodium ethylenediaminetetraacetate are uniformly mixed to obtain a premix;

[0102] (2) adding the premix to water and treating with ultrasound (40 kHz, 50° C.) for 40 min to obtain a mixed solution;

[0103] (3) Add osmanthus essential oil to the mixed solution, homogenize (temperature 65° C., first stir at 4000 rpm for 10 min, then continue stirring at 2000 rpm for 15 min), filter, and sterilize to obtain osmanthus essential oil essence.

[0104] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A method for extracting osmanthus essential oil, characterized in that: The specific steps include: S1, pretreatment: fresh, impurity-free osmanthus is repeatedly frozen and thawed 2-4 times, and vacuum dried to obtain pretreated osmanthus; S2, micronization: placing the pretreated osmanthus fragrans in S1 in an ultrafine airflow pulverizer to obtain ultrafine osmanthus fragrans powder; S3, adding the osmanthus ultrafine powder of S2 into an ethanol-isopropanol-ammonium sulfate tri-phase extraction system, performing a first ultrasonic treatment, adding a cosolvent, performing a second ultrasonic treatment, collecting the extract, evaporating to remove the cosolvent, and concentrating under reduced pressure to obtain osmanthus essential oil.

2. The method for extracting osmanthus essential oil according to claim 1, wherein: In step S1, the freeze-thaw is first frozen at -5 to -2°C for 12 to 24 hours, and then thawed naturally at room temperature.

3. The method for extracting osmanthus essential oil according to claim 1, characterized in that: In step S2, the particle size of the osmanthus ultrafine powder is 1-50 μm.

4. The method for extracting osmanthus essential oil according to claim 1, wherein: In step S3, the solid-liquid ratio of the osmanthus ultrafine powder to the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 1:10-15 g / mL; the concentration of ammonium sulfate in the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 5%-10% w / v, the concentration of ethanol is 50%-70% v / v, and the concentration of isopropanol is 30%-50% v / v.

5. The method for extracting osmanthus essential oil according to claim 1, characterized in that: In step S3, the first ultrasonic treatment is performed at 20-30 kHz and 40-50° C. for 1-3 h; and the second ultrasonic treatment is performed at 20-30 kHz and 25-35° C. for 30-60 min.

6. The method for extracting osmanthus essential oil according to claim 1, characterized in that: In step S3, the co-solvent is lactic acid and glycerol in a mass ratio of 1:2-4; the volume ratio of the co-solvent to the ethanol-isopropanol-ammonium sulfate tri-aqueous extraction system is 0.01-0.03:

1.

7. An osmanthus essential oil, characterized in that: The extract is obtained by the extraction method according to any one of claims 1 to 6.

8. Use of the osmanthus essential oil extracted by the extraction method according to any one of claims 1 to 6 in the preparation of products of inflammation inhibitors.

9. The use according to claim 8, characterized in that The concentration of osmanthus essential oil in the product is 1-5wt%.

10. The use according to claim 8, characterized in that The products are skin care products, including lotion, emulsion, cream, essence, ointment and facial mask.

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