Formula and preparation method of scald medicine

Abstract

The invention discloses a formula of a scald medicine and a preparation method thereof, and particularly relates to the technical field of traditional Chinese medicine agentia. Comprising the following components in parts by weight: 350-450 parts of beeswax, 50-60 parts of radix paeoniae rubra, 20-35 parts of angelica sinensis, 25-45 parts of ligusticum chuanxiong hort, 10-25 parts of myrrh, 18-22 parts of frankincense, 50-55 parts of golden cypress, 40-55 parts of fructus kochiae, 50-65 parts of ligusticum, 30-45 parts of cicada slough, 15-25 parts of schizonepeta, 50-65 parts of paris polyphylla, 90-110 parts of ampelopsis japonica, 40-60 parts of cortex dictamni, 20-40 parts of garden balsam stem, 25-35 parts of semen momordicae, 5-10 parts of borneol, 10-20 parts of aloe and 5-10 parts of liquorice. All the raw materials are jointly prepared into paste, and the paste is used for being externally applied to burn and scald areas and cannot be wrapped. The device not only improves the treatment effect of burns and scalds, but also improves the use experience of patients, and has wide application prospects and social value.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations, and more specifically, to a formula of a scald medicine and a preparation method thereof. Background Art

[0002] Burns and scalds are one of the common accidental injuries in daily life. Boiling water, boiling porridge, hot oil, hot steam, etc. can cause burns and scalds. The incidence rate is high and may cause serious complications, such as infection and scar formation, which have a serious impact on the patient's physical health and quality of life. Traditional treatments for burns and scalds mostly use Western medicine, such as antibiotics, disinfectants, painkillers, etc., but these drugs often have side effects, and for some patients with severe burns and scalds, the treatment effect is limited.

[0003] At present, burns are generally divided into three degrees according to their depth: first-degree burns: only the epidermis is damaged, the injured skin becomes red and swollen, and feels burning pain, but no blisters appear; second-degree burns: the dermis is damaged, with local redness, swelling, heat, unbearable pain, and obvious blisters; third-degree burns: the entire layer of skin including the fat, bones and muscles under the skin are damaged, the skin is charred and necrotic, but the pain is not severe at this time because many nerves are also damaged.

[0004] In recent years, as people's recognition of traditional Chinese medicine continues to increase, more and more traditional Chinese medicines have been used to treat burns and scalds, and have achieved certain therapeutic effects. However, we have found that the treatment of burns and scalds still has the following difficulties:

[0005] 1. Second-degree or third-degree burns can damage the deep tissue of the skin, causing a severe inflammatory reaction in the skin, releasing a large amount of inflammatory mediators, which can promote the formation of scars and make it difficult for the skin to regenerate naturally. Therefore, how to effectively control the inflammatory reaction and reduce the formation of scars is an important problem in the treatment of burns;

[0006] 2. Due to the high blood sugar level, diabetic patients have reduced skin healing ability and difficulty in wound healing. At the same time, high blood sugar will increase the risk of infection and further prolong the treatment cycle. Some diabetic patients may have other complications, such as cardiovascular disease and kidney disease, which requires more caution when choosing treatment drugs to avoid drug interactions or aggravation of complications.

[0007] 3. After burns and scalds, the skin barrier is damaged, and bacteria can easily invade the wound and cause infection. For patients with severe burns and scalds, the risk of infection is higher, which may lead to serious complications such as sepsis. With the widespread use of antibiotics, bacteria's resistance to antibiotics has gradually increased, making it more difficult to treat infections.

[0008] In summary, although the existing technology has made certain progress in the treatment of burns and scalds, there are still few treatment methods that can simultaneously meet the three requirements of leaving no scars, providing effective treatment for diabetic patients, and preventing sepsis. Especially for patients with second-degree or third-degree burns and scalds, the existing technology often cannot achieve rapid healing without leaving scars in a short period of time.

[0009] In view of the above situation, the present invention provides a formula of scald medicine and a preparation method thereof. Summary of the invention

[0010] In order to overcome the above defects of the prior art, the present invention provides a formula of a scald medicine and a preparation method thereof to solve the problems raised in the above background technology.

[0011] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a formula of a burn medicine, specifically comprising the following ingredients and their weight portions: 350-450 parts of yellow wax, 50-60 parts of red peony root, 20-35 parts of angelica, 25-45 parts of Chuanxiong, 10-25 parts of myrrh, 18-22 parts of frankincense, 50-55 parts of phellodendron, 40-55 parts of kochia scoparia, 50-65 parts of ligusticum, 30-45 parts of cicada shell, 15-25 parts of schizonepeta, 50-65 parts of parsnip, 90-110 parts of white ampel, 40-60 parts of dittany, 20-40 parts of radix schizonepetae, 25-35 parts of momordica, 5-10 parts of borneol, 10-20 parts of aloe and 5-10 parts of liquorice. All the raw materials are prepared into a paste together for external application on the burn area, and cannot be wrapped.

[0012] Preferably, the Paris polyphylla needs to be subjected to low-temperature drying within 24 hours after picking, the drying temperature is 30-40°C, the drying equipment is a vacuum freeze dryer, the vacuum degree is 10-50Pa, and the freezing temperature is -20--30°C.

[0013] Preferably, the content of berberine, the active ingredient of Phellodendron chinense, should be between 5% and 10%, the content of paeoniflorin in red peony root should be ≥2%, the content of ferulic acid in angelica root should be ≥0.05%, and the content of ferulic acid in Chuanxiong root should be ≥0.1%.

[0014] The present invention also provides a preparation method for preparing the above-mentioned scald medicine, which specifically comprises the following steps:

[0015] S1, yellow wax melting treatment, placing the yellow wax in a heating container, heating at a temperature of 120-150° C. until completely melted, to obtain melted yellow wax liquid, stirring at a speed of 30-50 r / min during the heating process, and stirring for 5-10 min;

[0016] S2, preparation and mixing of medicinal powder, respectively crushing red peony root, angelica, Chuanxiong, myrrh, frankincense, phellodendron, Kochia scoparia, Ligusticum chuanxiong, Periostracum cicadae, Nepeta tenuifolia, Paris polyphylla, Bletilla striata, Dictamni, Radix schizonepetae, Momordica charantia, and licorice into 80-120 mesh fine powder, and mixing in a mixer at a speed of 10-20 r / min for 30-60 min to obtain a mixed medicinal powder;

[0017] S3, the powder and yellow wax are mixed and stirred, the mixed powder prepared in step S2 is slowly added to the melted yellow wax liquid, and stirred at a speed of 50-80r / min for 10-15min, and then stirred at a speed of 100-150r / min for 20-30min, the stirring blade is a double-layer frame blade, and the distance between the blade and the bottom of the container is 5-10cm;

[0018] S4, add auxiliary materials and stir, add borneol and aloe vera during stirring, continue stirring for 10-15 minutes, stirring speed is 80-120r / min;

[0019] S5, ultrasonic oscillation treatment, the stirred mixture is treated with ultrasonic oscillation for 30-60 min, the frequency is 20-30 kHz, the power is 500-1000 W, the treatment container is made of stainless steel, the inner diameter of the container is 30-50 cm, and the height is 40-60 cm, to obtain a preliminary ointment;

[0020] S6. Standing and aging: placing the preliminary ointment in a ceramic container, the inner wall of which is coated with a layer of nano-silver antibacterial coating, the thickness of which is 50-100 nm, and sealing and standing for 24-48 hours, the ambient temperature is controlled at 20-25° C., and the humidity is 40%-60%, to obtain a finished burn ointment.

[0021] Preferably, the outer packaging of the paste medicine is made of a composite material with a one-way air permeability function, the composite material includes a polylactic acid layer and a nanoporous polyethylene layer, wherein the thickness of the polylactic acid layer is 0.1-0.2 mm, the thickness of the nanoporous polyethylene layer is 0.05-0.1 mm, and the air permeability of the composite material is 500-1000 ml / m 2 ·24h.

[0022] Preferably, rosemary extract is added as a stabilizer during the preparation of the drug, the amount of the rosemary extract added is 0.5-1% of the total weight of the drug, and the content of carnosic acid, an active ingredient in the rosemary extract, is ≥20%.

[0023] Preferably, it also includes a traditional Chinese medicine cleaning solution used in conjunction with the paste medicine. The traditional Chinese medicine cleaning solution is prepared by mixing and boiling honeysuckle, wild chrysanthemum and dandelion in a weight ratio of 1:1:2. The boiling time is 30-60 minutes. The boiling container is a ceramic casserole. The cleaning solution temperature is controlled at 30-40°C. The cleaning time is 3-5 minutes. After cleaning, the solution is naturally dried before applying the burn medicine.

[0024] Preferably, the total bacterial count of the finished burn ointment shall not exceed 1000 CFU / g, the total mold and yeast count shall not exceed 100 CFU / g, and Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli shall not be detected in every 1g.

[0025] Preferably, the continuous use period for first-degree and second-degree burns and scalds is 3-7 days, and the use period for third-degree burns and scalds is 8-12 days.

[0026] Technical effects and advantages of the present invention:

[0027] 1. The present invention carefully selects and proportions a variety of Chinese herbal medicine ingredients, such as yellow wax, red peony root, Chinese angelica, Chuanxiong, etc. These ingredients have the effects of clearing away heat and detoxifying, promoting blood circulation and removing blood stasis, promoting tissue regeneration and relieving pain in traditional Chinese medicine theory. After a specific preparation process, these ingredients can give full play to their pharmacological effects and show significant therapeutic effects on first-degree, second-degree and third-degree burns and scalds. At the same time, the burn medicine of the present invention is suitable for patients of different ages and degrees of burns and scalds, and has a wide range of applicability;

[0028] 2. The preparation method of the present invention comprises the steps of melting yellow wax, preparing and mixing medicinal powder, mixing and stirring medicinal powder and yellow wax, adding and stirring auxiliary materials, ultrasonic oscillation treatment and static aging, thereby ensuring the effective extraction and mixing of medicinal ingredients and the stability and uniformity of the ointment. In addition, by adding rosemary extract as a stabilizer, the stability and long-term storage effect of the ointment are further improved, providing a strong guarantee for the stability of the drug efficacy.

[0029] 3. The present invention not only provides an efficient burn ointment, but also provides a Chinese medicine cleaning solution and a specific usage plan. The Chinese medicine cleaning solution is made from Chinese herbal medicines such as honeysuckle, wild chrysanthemum, and dandelion, and has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain. It can clean wounds and promote the absorption of drugs. At the same time, the outer packaging of the ointment of the present invention adopts a composite material with one-way breathable function, which can keep the ointment dry and fresh, and improve the patient's usage experience. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is the overall flow chart of the present invention. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] Embodiment 1,

[0033] The embodiment of the present invention provides a formula of a burn medicine, which specifically includes the following components and their weight portions:

[0034] 350 parts of yellow wax, 50 parts of red peony root, 20 parts of angelica, 25 parts of Chuanxiong, 10 parts of myrrh, 18 parts of frankincense, 50 parts of Phellodendron chinense with berberine content of 5%, 40 parts of Kochia scoparia, 50 parts of Ligusticum chuanxiong, 30 parts of Periostracum cicadae, 15 parts of Schizonepeta, 50 parts of Paris polyphylla (processed in a vacuum freeze dryer within 24h as required after picking, vacuum degree 10Pa, freezing temperature -20℃, drying temperature 30℃), 90 parts of Bletilla striata, 40 parts of Dictamni, 20 parts of Herba spermatae, 25 parts of Semen Momordica, 5 parts of Borneolum, 10 parts of Aloe, and 5 parts of Licorice.

[0035] The embodiment of the present invention also provides a preparation method for preparing the above-mentioned scald medicine, which specifically comprises the following steps:

[0036] S1. Place yellow wax in a heating container, heat at 120°C, stir at 30r / min, and stir for 5min until completely melted to obtain melted yellow wax liquid;

[0037] S2, crushing the above medicinal materials except borneol and aloe into 80 mesh fine powder respectively, and mixing them in a mixer at a speed of 10r / min for 30min to obtain mixed medicinal powder;

[0038] S3. Slowly add the mixed powder into the melted yellow wax solution, stir at 50 r / min for 10 min, then stir at 100 r / min for 20 min. The stirring blade is a double-layer frame blade, and the blade is 5 cm away from the bottom of the container.

[0039] S4. Add borneol and aloe vera during stirring and stir at 80 r / min for 10 min;

[0040] S5, treating the mixture with ultrasonic oscillation for 30 min, with a frequency of 20 kHz and a power of 500 W, in a stainless steel treatment container with an inner diameter of 30 cm and a height of 40 cm, to obtain a preliminary ointment;

[0041] S6. Place the preliminary ointment in a ceramic container with a 50nm nano-silver antibacterial coating on the inner wall, seal it in an environment of 20°C and 40% humidity and let it stand for 24 hours to obtain a finished burn ointment.

[0042] Embodiment 2,

[0043] The embodiment of the present invention provides a formula of a burn medicine, which specifically includes the following components and their weight portions:

[0044] 400 parts of yellow wax, 55 parts of red peony root with 2.5% paeoniflorin content, 30 parts of angelica with 0.06% ferulic acid content, 35 parts of Chuanxiong with 0.12% ferulic acid content, 18 parts of myrrh, 20 parts of frankincense, 53 parts of phellodendron with 7% berberine, 48 parts of Kochia scoparia, 58 parts of Ligusticum chuanxiong, 38 parts of Periostracum cicadae, 20 parts of Schizonepeta, 58 parts of Paris polyphylla (vacuum freeze-drying parameters after picking: vacuum degree 30Pa, freezing temperature -25°C, drying temperature 35°C), 100 parts of Bletilla striata, 50 parts of Dictamni, 30 parts of Herba schizonepetae, 30 parts of Semen Momordica, 8 parts of Borneolum, 15 parts of Aloe, and 8 parts of Licorice.

[0045] The embodiment of the present invention also provides a preparation method for preparing the above-mentioned scald medicine, which specifically comprises the following steps:

[0046] S1. Melt the yellow wax at 135°C, stir at 40r / min, and stir for 8min;

[0047] S2, crush the medicinal materials into 100 mesh fine powder, and mix them in a mixer at 15r / min for 45min;

[0048] S3. Add the mixed powder to the melted yellow wax liquid, stir at 65r / min for 13min, then at 125r / min for 25min, with the blade 8cm away from the bottom of the container;

[0049] S4. Add borneol and aloe vera and stir at 100 r / min for 13 min.

[0050] S5, ultrasonic oscillation for 45 min, frequency 25 kHz, power 750 W, container inner diameter 40 cm, height 50 cm.

[0051] S6. Place the nanosilver antibacterial coating in a ceramic container with a thickness of 75 nm and place it in an environment of 23°C and 50% humidity for 36 hours.

[0052] Embodiment 3,

[0053] The embodiment of the present invention provides a formula of a burn medicine, which specifically includes the following components and their weight portions:

[0054] 450 parts of yellow wax, 60 parts of red peony root with 3% paeoniflorin content, 35 parts of angelica with 0.08% ferulic acid content, 45 parts of Chuanxiong with 0.15% ferulic acid content, 25 parts of myrrh, 22 parts of frankincense, 55 parts of phellodendron with 10% berberine, 55 parts of Kochia scoparia, 65 parts of Ligusticum chuanxiong, 45 parts of Periostracum cicadae, 25 parts of Schizonepeta tenuifolia, 65 parts of Paris polyphylla (vacuum freeze-drying parameters after picking: vacuum degree 50Pa, freezing temperature -30°C, drying temperature 40°C), 110 parts of Bletilla striata, 60 parts of Dictamni cortex, 40 parts of Radix spermatii, 35 parts of Momordica charantia, 10 parts of borneol, 20 parts of aloe, and 10 parts of liquorice.

[0055] The embodiment of the present invention also provides a preparation method for preparing the above-mentioned scald medicine, which specifically comprises the following steps:

[0056] S1. Melt the yellow wax at 150℃, stir at 50r / min, and stir for 10min;

[0057] S2, crush the medicinal materials into 120 mesh fine powder, and mix them in a mixer at 20r / min for 60min;

[0058] S3, add the mixed powder to the melted yellow wax liquid, stir at 80r / min for 15min, then stir at 150r / min for 30min, with the blade 10cm away from the bottom of the container;

[0059] S4, add borneol and aloe vera and stir at 120r / min for 15min;

[0060] S5, ultrasonic oscillation for 60 min, frequency 30 kHz, power 1000 W, container inner diameter 50 cm, height 60 cm;

[0061] S6. Place the ceramic container with a nano-silver antibacterial coating of 100 nm in thickness in an environment of 25°C and 60% humidity for 48 hours.

[0062] In the above embodiments, the prepared scald ointment meets the microbial limit standards of finished scald ointment, such as the total number of bacteria shall not exceed 1000 CFU / g, the total number of molds and yeasts shall not exceed 100 CFU / g, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli shall not be detected in 1g, and the continuous use period for first-degree and second-degree burns is 3-7 days, and the use period for third-degree burns is 8-12 days.

[0063] At the same time, the matching Chinese medicine cleaning liquid is mixed and boiled according to the weight ratio of honeysuckle, wild chrysanthemum and dandelion of 1:1:2, the boiling time is 30-60 minutes, the boiling time is 30-40℃ in a ceramic casserole, the cleaning liquid temperature is 30-40℃, the cleaning time is 3-5 minutes, and the burn medicine is applied after natural drying after cleaning. The medicine is used in conjunction with specific parameters, such as irradiation distance of 20-30cm, irradiation time of 10-20min, infrared wavelength of 8-14μm, and irradiation power of 30-50W to irradiate the scalded area with an infrared irradiation device to promote drug absorption and blood circulation in the scalded area.

[0064] The burn medicine prepared in the above embodiment has different usage time for different patients with different physiques and degrees of burns and scalds, but the summary data of patients' use shows that the longest usage time for first-degree and second-degree burns and scalds is 7 days, and the longest usage time for third-degree burns and scalds is 12 days. In many years of use practice, the patient recovery rate is 100%, without scars, recurrence, and sequelae.

[0065] Regarding the description of the raw material composition, the above-disclosed usage amounts all give a defined range, and these ranges constitute the proportion of the above-disclosed dosage. For example, yellow wax, whose main component is the ester formed by higher fatty acids and higher monohydric alcohols, has slightly different chemical components due to different bee species and origins. The main chemical components are: carbohydrates 14%, monoesters 42%, diesters 14%, triesters 3%, hydroxymonoesters 4%, hydroxypolyesters 8%, acidic polyesters 1%, free acids 12%, and other substances 2%. In addition, it also contains carotenoids, vitamin A, a small amount of aromatic substances and trace elements, etc. The present invention takes its effects of astringing sores, promoting tissue regeneration and relieving pain. In the prescription disclosed in the present invention, when its dosage is less than 300 parts, the effect of the prescription cannot be achieved, and when it is greater than 500 parts, the raw materials are wasted, the efficacy is not increased, and because its dosage is too large, the combined effect of other drugs is reduced, resulting in a decrease in the effect. The usage range of borneol is 5-10 parts, which is very different from the usage ratio of yellow wax. The reason is that the present invention aims to use borneol to clear all the orifices and disperse stagnant fire, but it is toxic. It is used in combination with Phellodendron chinense to clear away heat and purge fire, detoxify and reduce swelling, dry dampness and astringe sores, relieve pain and itching, but the prescription is not a single or simple combination of several flavors, but a combination of multiple raw materials. Phellodendron chinense is also compatible with Schizonepeta tenuifolia to regulate qi and blood, break up knots and detoxify. So for the usage, Phellodendron chinense 50-55 parts, Schizonepeta tenuifolia 15-25 parts, and borneol 5-10, when the usage of borneol is less than 2 parts, its effect disappears, and when it is greater than 15 parts, its auxiliary effect is reduced, resulting in changes in the compatibility properties of the entire prescription and changes in the medicinal properties.

[0066] Another example: red peony root, Chinese angelica, Chuanxiong, myrrh, frankincense, red peony root and Chinese angelica are compatible, red peony root clears heat and cools blood, removes stasis and relieves pain; Chinese angelica promotes blood circulation, replenishes blood and relieves pain, while red peony root and Phellodendron are compatible, red peony root clears heat and cools blood and relieves pain, Phellodendron specializes in damp heat in the lower jiao, and the two are used together, which has the effect of clearing heat, cooling blood and drying dampness. Red peony root and Chuanxiong can significantly reduce whole blood viscosity, whole blood reduced viscosity, whole blood relative viscosity, red blood cell deformation index and red blood cell aggregation index. Myrrh and frankincense are compatible to promote blood circulation and relax muscles. In the present invention, red peony root, Chinese angelica, Chuanxiong, myrrh, frankincense are mainly used to promote qi and blood, relax muscles and bones, clear heat and toxicity, eliminate qi and blood stagnation, and can achieve rapid epidermal repair. And the dosage is controlled to achieve this purpose, 50-60 parts of red peony root, 20-35 parts of angelica, 25-45 parts of Chuanxiong, 18-22 parts of frankincense, 10-25 parts of myrrh, among which 50-60 parts of red peony root are the largest. In addition, the present invention needs to use angelica to protect the liver and prevent the reduction of liver glycogen, red peony root improves insulin resistance, lowers blood sugar and blood lipids, and Phellodendron chinense lowers blood pressure and blood sugar, which has achieved the same therapeutic effect on diabetic patients;

[0067] For example: Radix Bletillae clears away heat, detoxifies and resolves stagnation, Radix Dictamni dispels wind, relieves itching and detoxifies, Herba Polygoni Multiflori dispels rheumatism and treats heat toxins, and Semen Momordicae reduces swelling, resolves stagnation and removes toxins; 90-110 parts of Radix Bletillae, 40-60 parts of Radix Dictamni, 20-40 parts of Herba Polygoni Multiflori, and 25-35 parts of Semen Momordicae, with Radix Bletillae used in the largest amount, leading the heat-clearing and detoxification, stagnation-resolving and pain-relieving, and promoting tissue regeneration and healing sores. Radix Dictamni combined with Radix Bletillae can help it clear away heat, detoxify, heal sores and promote tissue regeneration, and can also dispel dampness and relieve itching, while Herba Polygoni Multiflori combined with Radix Dictamni can further dispel rheumatism, treat heat toxins, and prevent and treat eczema and heat rash, while Semen Momordicae and Rhizoma Parispida clear away heat and detoxify, and Radix Ligustici Radix, Periostracum Cicadae, and Herba Schizonepetae clear away heat and resolve the exterior symptoms, and the application of these effects can detoxify and promote tissue regeneration while clearing away heat and detoxifying, preventing various possible problems;

[0068] Another example: 50-55 parts of Phellodendron chinense and 40-55 parts of Kochia scoparia. The present invention needs to prevent the occurrence of sepsis, so the antibacterial function of Phellodendron chinense, Kochia scoparia and Borneol is used. Kochia scoparia is compatible with Dictamni cortex and is specifically used for skin itching. When the amount of Kochia scoparia is less than 30 parts, its ability to inhibit skin fungi in the finished ointment decreases, and its compatibility with Dictamni cortex decreases. When it is greater than 60 parts, Kochia scoparia is cold in nature and is a yin-tonifying drug. A large amount of Kochia scoparia will change the medicinal properties of the whole drug.

[0069] Another example: 10-20 parts of aloe vera and 5-10 parts of licorice, aloe vera is used to enhance the anti-inflammatory, antibacterial and moisturizing effects, while licorice is used to harmonize the medicinal properties and enhance the overall efficacy of the drug.

[0070] Through the above description, the present invention has provided the principle of achieving rapid healing of wound surface, preventing sepsis, and still achieving rapid healing of wound surface for diabetic patients. In long-term clinical medical treatment, the prescription can cure first-degree and second-degree burns and scalds after continuous use for 3-7 days, and cure third-degree burns and scalds after continuous use for 8-12 days without leaving scars, recurrence, or sequelae. The cure rate of hundreds of patients using the prescription is 100%, and the prescription is an excellent external medicine for treating burns and scalds with traditional Chinese medicine.

[0071] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A formula of a scald medicine, characterized in that: Specifically, it includes the following ingredients and their weight portions: 350-450 parts of yellow wax, 50-60 parts of red peony root, 20-35 parts of angelica, 25-45 parts of Chuanxiong, 10-25 parts of myrrh, 18-22 parts of frankincense, 50-55 parts of phellodendron, 40-55 parts of kochia scoparia, 50-65 parts of ligusticum, 30-45 parts of cicada shells, 15-25 parts of schizonepeta, 50-65 parts of parsnip, 90-110 parts of white ampel, 40-60 parts of dittany, 20-40 parts of radix scutellariae, 25-35 parts of momordica seeds, 5-10 parts of borneol, 10-20 parts of aloe and 5-10 parts of liquorice. All the raw materials are prepared into a paste together for external application on the burned area, and it cannot be wrapped.

2. The formula of the scald medicine according to claim 1, characterized in that: The Paris polyphylla needs to be low-temperature dried within 24 hours after being picked, the drying temperature is 30-40°C, the drying equipment is a vacuum freeze dryer, the vacuum degree is 10-50Pa, and the freezing temperature is -20--30°C.

3. The formula of the scald medicine according to claim 2, characterized in that: The content of berberine, the active ingredient of Phellodendron chinense, should be between 5% and 10%, the content of paeoniflorin in red peony root should be ≥2%, the content of ferulic acid in angelica root should be ≥0.05%, and the content of ferulic acid in Chuanxiong root should be ≥0.1%.

4. A preparation method for preparing the scald medicine according to claim 3, characterized in that: The specific steps include: S1, yellow wax melting treatment, placing the yellow wax in a heating container, heating at a temperature of 120-150° C. until completely melted, to obtain melted yellow wax liquid, stirring at a speed of 30-50 r / min during the heating process, and stirring for 5-10 min; S2, preparation and mixing of medicinal powder, respectively crushing red peony root, angelica, Chuanxiong, myrrh, frankincense, phellodendron, Kochia scoparia, Ligusticum chuanxiong, Periostracum cicadae, Nepeta tenuifolia, Paris polyphylla, Bletilla striata, Dictamni, Radix schizonepetae, Momordica charantia, and licorice into 80-120 mesh fine powder, and mixing in a mixer at a speed of 10-20 r / min for 30-60 min to obtain a mixed medicinal powder; S3, the powder and yellow wax are mixed and stirred, the mixed powder prepared in step S2 is slowly added to the melted yellow wax liquid, and stirred at a speed of 50-80r / min for 10-15min, and then stirred at a speed of 100-150r / min for 20-30min, the stirring blade is a double-layer frame blade, and the distance between the blade and the bottom of the container is 5-10cm; S4, add auxiliary materials and stir, add borneol and aloe vera during stirring, continue stirring for 10-15 minutes, stirring speed is 80-120r / min; S5, ultrasonic oscillation treatment, the stirred mixture is treated with ultrasonic oscillation for 30-60 min, the frequency is 20-30kHz, the power is 500-1000W, the treatment container is made of stainless steel, the inner diameter of the container is 30-50cm, and the height is 40-60cm, to obtain a preliminary ointment; S6. Standing and aging: placing the preliminary ointment in a ceramic container, the inner wall of which is coated with a layer of nano-silver antibacterial coating, the thickness of which is 50-100 nm, and sealing and standing for 24-48 hours, the ambient temperature is controlled at 20-25° C., and the humidity is 40%-60%, to obtain a finished burn ointment.

5. The preparation method according to claim 4, characterized in that: The outer packaging of the paste medicine is made of a composite material with one-way air permeability. The composite material includes a polylactic acid layer and a nanoporous polyethylene layer. The thickness of the polylactic acid layer is 0.1-0.2 mm, the thickness of the nanoporous polyethylene layer is 0.05-0.1 mm, and the air permeability of the composite material is 500-1000 ml / m 2 ·24h.

6. The preparation method according to claim 5, characterized in that: During the preparation of the medicine, rosemary extract is added as a stabilizer, the added amount of the rosemary extract is 0.5-1% of the total weight of the medicine, and the content of carnosic acid, an effective ingredient in the rosemary extract, is ≥20%.

7. The preparation method according to claim 6, characterized in that: It also includes a traditional Chinese medicine cleaning liquid used in conjunction with the ointment medicine. The traditional Chinese medicine cleaning liquid is made by mixing honeysuckle, wild chrysanthemum, and dandelion in a weight ratio of 1:1:2 and boiling for 30-60 minutes. The boiling container is a ceramic casserole. The cleaning liquid temperature is controlled at 30-40°C and the cleaning time is 3-5 minutes. After cleaning, it is naturally dried before applying burn medicine.

8. The preparation method according to claim 7, characterized in that: The total bacterial count of the finished burn ointment shall not exceed 1000 CFU / g, the total mold and yeast count shall not exceed 100 CFU / g, and Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli shall not be detected in every 1g.

9. The preparation method according to claim 8, characterized in that: The continuous use period for first-degree and second-degree burns is 3-7 days, and the use period for third-degree burns is 8-12 days.

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