Magnetic resonance imaging enhancement device and system

By using the resonant ring and closed substrate of the metamaterial array in MRI, the automatic detuning and resonant response in the MRI transmission and reception stage is achieved, and the limitations of the existing MRI signal-to-noise ratio enhancement method is solved, which significantly improves the MRI Signal-to-noise ratio and image quality.

CN119439016APending Publication Date: 2025-02-14TSINGHUA UNIVERSITY
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Patent Information

Application Number
CN202411515433.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-29
Publication Date
2025-02-14

AI Technical Summary

Technical Problem

The existing MRI signal-to-noise ratio enhancement methods have limitations, and imaging quality still needs to be further improved.

Method used

A metamaterial array is adopted, including periodically arranged metamaterial units, which contain a closed substrate with through holes and a resonant ring. The resonant ring is automatically detuned during the MRI emission stage and resonates during the receiving stage to improve the MRI imaging quality.

Benefits of technology

Through automatic detuning and resonant response, the signal-to-noise ratio of MRI is significantly improved, image quality is improved, and the original operating parameters settings of the MRI device remain unchanged.

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Abstract

The invention relates to a magnetic resonance imaging enhancement device and system. The magnetic resonance imaging enhancement device comprises: a metamaterial array; the metamaterial array comprises a plurality of metamaterial units which are periodically arranged, and each metamaterial unit comprises a closed substrate with a through hole and a resonant ring; the resonant ring is embedded into the closed substrate; the resonance ring is used for enabling the metamaterial array to be automatically detuned in the transmitting stage of magnetic resonance imaging and generate resonance in the receiving stage of magnetic resonance imaging so as to improve the quality of magnetic resonance imaging. According to the magnetic resonance imaging enhancement device provided by the invention, in an MRI emission stage, the resonance ring enables the enhancement device to exit a resonance state through an automatic detuning function, so that interference on a normal excitation process of magnetic resonance imaging equipment is avoided; in the MRI receiving stage, the resonance response of the resonant ring and the resonator enables the enhancement device to enhance the radio frequency magnetic field signal emitted by the measured object, so that the enhancement of the MRI receiving signal is realized, the signal-to-noise ratio of imaging is remarkably improved, and the image quality is further improved.
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Description

Technical Field

[0001] The present application relates to the field of magnetic resonance imaging enhancement technology, and in particular to a magnetic resonance imaging enhancement device and system. Background Art

[0002] Magnetic resonance imaging (MRI), as an imaging technology widely used in clinical medicine, has attracted much attention for its significant advantages of non-invasiveness, no ionizing radiation, high tissue contrast and multi-parameter imaging.

[0003] In MRI, the signal-to-noise ratio (SNR) is a key indicator for measuring image quality, which directly affects the image resolution and imaging speed. Therefore, effectively enhancing the SNR is crucial to improving the imaging performance of MRI. Currently, the commonly used methods for enhancing the SNR of MRI include increasing the static magnetic field strength, using contrast agents, and applying surface coils.

[0004] However, the above-mentioned MRI SNR enhancement methods still have their limitations, and the imaging quality still needs to be further enhanced. Summary of the invention

[0005] Based on this, it is necessary to provide a magnetic resonance imaging enhancement device and system that can enhance the imaging quality of MRI in order to solve the above technical problems.

[0006] In a first aspect, the present application provides a magnetic resonance imaging enhancement device, the magnetic resonance imaging enhancement device comprising: a metamaterial array;

[0007] The metamaterial array includes a plurality of periodically arranged metamaterial units, wherein the metamaterial unit includes a closed substrate with a through hole and a resonant ring; the resonant ring is embedded in the closed substrate;

[0008] The resonant ring is used to automatically detune the metamaterial array during the transmitting phase of magnetic resonance imaging and to resonate during the receiving phase of magnetic resonance imaging to improve the quality of magnetic resonance imaging.

[0009] The magnetic resonance imaging enhancement device provided by the present application has the following characteristics: in the MRI transmission phase, the resonant ring uses the automatic detuning function to make the enhancement device exit the resonance state, thereby avoiding interference with the normal excitation process of the magnetic resonance imaging equipment; in the MRI reception phase, the resonant response of the resonant ring and the resonator enables the enhancement device to enhance the radio frequency magnetic field signal emitted by the object under test, thereby achieving the enhancement of the MRI reception signal, significantly improving the imaging signal-to-noise ratio, and thus improving the image quality.

[0010] In one embodiment, the resonant ring includes a substrate material, a metal wire and a varactor diode;

[0011] The variable capacitance diode is arranged on the metal wire, and the metal wire is embedded in the substrate material along the cross section of the substrate material.

[0012] The present application utilizes the rectifying effect of the varactor diode 10012 and the characteristic that the junction capacitance changes with the bias voltage at both ends, so that the resonant ring 1001 equipped with the varactor diode 10012 has the ability to automatically tune the resonant frequency as the excitation power of the external radio frequency magnetic field changes. This adaptive tuning characteristic enables the metamaterial array 10 to resonate in the magnetic resonance radio frequency receiving stage to enhance the radio frequency magnetic field, and automatically detune in the magnetic resonance radio frequency transmitting stage, thereby ensuring that the original working parameter settings of the MRI device remain unchanged, significantly improving the quality and efficiency of MRI imaging.

[0013] In one of the embodiments, the metamaterial unit further comprises: a resonator, the resonator being wound along an outer spiral of the closed substrate;

[0014] Resonators are used to make the metamaterial array resonate.

[0015] In the embodiment of the present application, the magnetic resonance imaging enhancement device also includes a resonator, which is used to enhance the local radio frequency magnetic field in the magnetic resonance radio frequency receiving stage, thereby further improving the magnetic resonance imaging signal-to-noise ratio and image quality.

[0016] In one embodiment, the magnetic resonance imaging enhancement device further includes: a substrate, and the substrate is bonded to the metamaterial array.

[0017] In one embodiment, a plurality of slit patterns are disposed on the substrate.

[0018] In the embodiment of the present application, a plurality of slit patterns are provided on the substrate so that the substrate can substantially fit the object to be measured, thereby improving the signal-to-noise ratio improvement effect of the magnetic resonance imaging enhancement device.

[0019] In one embodiment, the magnetic resonance imaging enhancement device further comprises: a bonding key, which is used to connect the substrate and the metamaterial array.

[0020] The magnetic resonance imaging enhancement device with a bonding key provided in the present application enables the substrate and the metamaterial array to be bonded together, so that the metamaterial array can accurately obtain the radio frequency magnetic field signal generated by the object under test, thereby enhancing the imaging effect of magnetic resonance imaging.

[0021] In one embodiment, the closed substrate is made of a polymer material.

[0022] In one embodiment, the closed substrate comprises a toroidal substrate, the major radius of the toroidal substrate is 15 mm, and the tube radius of the toroidal substrate is 1.8 mm.

[0023] In one embodiment, the wire diameter of the resonator is 0.6 mm, the width of the substrate material is 0.5 mm, the thickness is 0.035 mm, and the capacitance of the varactor diode is 18 pF.

[0024] In a second aspect, the present application provides a magnetic resonance imaging enhancement system, the magnetic resonance imaging enhancement system comprising: the magnetic resonance imaging enhancement device, the object to be measured and the magnetic resonance imaging equipment as described in the first aspect above;

[0025] The magnetic resonance imaging enhancement device and the object to be measured are fitted together;

[0026] The magnetic resonance imaging enhancement device is used to automatically detune during the radio frequency transmission stage of the magnetic resonance imaging device to avoid affecting the excitation of the object to be measured; and to resonate and enhance the magnetic resonance signal generated by the object to be measured during the radio frequency receiving stage of the magnetic resonance imaging device.

[0027] The above-mentioned magnetic resonance imaging enhancement device and system, the above-mentioned magnetic resonance imaging enhancement device includes: a metamaterial array; the metamaterial array includes a plurality of periodically arranged metamaterial units, the metamaterial unit includes a closed substrate with a through hole and a resonant ring; the resonant ring is embedded in the closed substrate; the resonant ring is used to automatically detune the metamaterial array in the transmitting stage of magnetic resonance imaging, and to resonate in the receiving stage of magnetic resonance imaging, so as to improve the quality of magnetic resonance imaging. The magnetic resonance imaging enhancement device provided by the present application, in the MRI transmitting stage, the resonant ring uses the automatic detuning function to make the enhancement device exit the resonant state to avoid interfering with the normal excitation process of the magnetic resonance imaging device; in the MRI receiving stage, the resonant response of the resonant ring and the resonator enables the enhancement device to enhance the radio frequency magnetic field signal emitted by the object under test, thereby achieving the enhancement of the MRI receiving signal, significantly improving the imaging signal-to-noise ratio, and thus improving the image quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the technical solutions in the embodiments of the present application or related technologies, the drawings required for use in the embodiments of the present application or related technical descriptions will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0029] FIG1 is a diagram showing an application environment of a magnetic resonance imaging enhancement device according to an embodiment;

[0030] Figure 2 is a schematic structural diagram of a magnetic resonance imaging enhancement device in one embodiment;

[0031] Figure 3A schematic cross-sectional view of a magnetic resonance imaging enhancement metamaterial unit in one embodiment;

[0032] Figure 4 is a schematic diagram of the structure of a resonant ring in a metamaterial unit in an embodiment;

[0033] Figure 5 is a schematic structural diagram of a resonator in a metamaterial unit in an embodiment;

[0034] Figure 6 A schematic diagram of a resonance response experimental result of a magnetic resonance imaging enhancement device in one embodiment;

[0035] Figure 7 The simulation result of the radio frequency magnetic field enhancement factor corresponding to the cylindrical object under test in one embodiment;

[0036] Figure 8 is a simulation result of the radio frequency magnetic field enhancement factor corresponding to a planar object under test in an embodiment;

[0037] Fig. 9 The simulation result of the radio frequency magnetic field enhancement factor corresponding to the spherical object under test in one embodiment;

[0038] Fig.10 Magnetic resonance imaging results of a magnetic resonance imaging enhancement device in an embodiment (wherein the left column, the middle column, and the right column are imaging results of the magnetic resonance imaging enhancement device conforming to the object to be measured having a cylindrical shape, a planar shape, and a spherical shape, respectively);

[0039] Description of Figure Numbers:

[0040] 01-Magnetic resonance imaging enhancement system;

[0041] 011-test object;

[0042] 012-Magnetic resonance imaging enhancement device;

[0043] 013-Magnetic resonance imaging equipment;

[0044] 10-Metamaterial array;

[0045] 20-Substrate;

[0046] 30-fit key;

[0047] 100-metamaterial unit;

[0048] 1000 - closed base;

[0049] 1001-resonance ring;

[0050] 1002- resonator;

[0051] 10010-substrate material;

[0052] 10011 - Metal wire;

[0053] 10012-Varactor diode. DETAILED DESCRIPTION

[0054] In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0055] Magnetic resonance imaging (MRI), as an imaging technology widely used in clinical medicine, has attracted much attention for its significant advantages of non-invasiveness, no ionizing radiation, high tissue contrast and multi-parameter imaging. In MRI, the signal-to-noise ratio (SNR) is a key indicator for measuring image quality, which directly affects the resolution and imaging speed of the image. Therefore, effectively enhancing the SNR of the image is crucial to improving the imaging performance of MRI. At present, commonly used signal-to-noise ratio enhancement methods include increasing the static magnetic field strength, using contrast agents, and applying surface coils. However, each of these methods has certain limitations. For example, enhancing the static magnetic field strength may lead to an aggravation of the biodielectric effect, the use of contrast agents is accompanied by the risk of allergic reactions, and the surface coil is insufficient in the imaging effect of deep tissues. That is, the above-mentioned MRI SNR enhancement method still has the problem of poor imaging quality. The present application aims to solve this problem.

[0056] After introducing the background technology of the magnetic resonance imaging enhancement device provided by the embodiment of the present application, the implementation environment involved in the magnetic resonance imaging enhancement device provided by the embodiment of the present application will be briefly described below. The magnetic resonance imaging enhancement device provided by the embodiment of the present application can be applied to the magnetic resonance imaging enhancement system 01 as shown in Figure 1, and the magnetic resonance imaging enhancement system 01 includes a measured object 011, a magnetic resonance imaging enhancement device 012 and a magnetic resonance imaging device 013, wherein the magnetic resonance imaging enhancement device 012 is placed in the magnetic resonance imaging device 013 after being attached to the measured object 011.

[0057] When performing magnetic resonance imaging, in the radio frequency transmission stage, the magnetic resonance imaging device 013 transmits radio frequency pulses to the object under test 011, and in the radio frequency reception stage, the object under test 011 sends out a magnetic resonance signal, which is then received by the magnetic resonance imaging device 013 after being enhanced by the magnetic resonance imaging enhancement device 012. In this process, the radio frequency magnetic field signal emitted by the object under test 011 is locally enhanced through the resonance response in the magnetic resonance imaging enhancement device 012, thereby improving the image quality.

[0058] The technical solution of the present application and how the technical solution of the present application solves the above-mentioned technical problems are described in detail below with specific embodiments. The following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be repeated in some embodiments. The embodiments of the present application will be described below in conjunction with the accompanying drawings.

[0059] In one embodiment, Figure 2 As shown, a magnetic resonance imaging enhancement device 01 is provided, comprising: a metamaterial array 10;

[0060] The metamaterial array 10 includes a plurality of periodically arranged metamaterial units 100, the metamaterial units 100 (see Figure 3 ) includes a closed substrate 1000 with a through hole and a resonant ring 1001; the resonant ring 1001 is embedded in the closed substrate 1000;

[0061] The resonant ring 1001 is used to automatically detune the metamaterial array 10 during the transmitting phase of magnetic resonance imaging, and to generate resonance during the receiving phase of magnetic resonance imaging, so as to improve the quality of magnetic resonance imaging.

[0062] Among them, see Figure 2 , a total of three magnetic resonance imaging enhancement devices 01 corresponding to objects under test of different shapes are provided. For example, the leftmost image refers to the magnetic resonance imaging enhancement device 01 corresponding to the curved surface of a cylindrical object under test, the middle image refers to the magnetic resonance imaging enhancement device 01 corresponding to the flat surface of a cylindrical object under test, and the rightmost image refers to the magnetic resonance imaging enhancement device 01 corresponding to the flat surface of a spherical object under test.

[0063] Among them, the metamaterial array 10 can significantly enhance the radio frequency magnetic field in MRI.

[0064] The material of the closed substrate 1000 with through holes is a polymer material. The closed substrate with through holes includes a torus-shaped substrate, a hollow polygonal substrate and an elliptical torus-shaped substrate. When the closed substrate with through holes is a torus-shaped substrate, the main radius of the torus-shaped substrate is 15 mm, and the tube radius of the torus-shaped substrate is 1.8 mm.

[0065] Among them, the typical thickness of the metamaterial unit 100 is less than 4 mm, and it has the significant advantages of compact structure and small size.

[0066] It should be noted that when performing magnetic resonance imaging, the magnetic resonance imaging device 300 first transmits a radio frequency pulse to the object 100 through the magnetic resonance imaging enhancement device 200. To avoid interference with the normal excitation process of the magnetic resonance imaging device 300, the metamaterial array 1000 exits the resonance state through the automatic detuning function. After the object 100 receives the radio frequency pulse, the metamaterial array 1000 enhances the radio frequency magnetic field signal emitted by the object 100, thereby enhancing the MRI receiving signal, significantly improving the imaging signal-to-noise ratio, and thus improving the image quality. During the entire magnetic resonance imaging process, the radio frequency magnetic field signal emitted by the object 100 is enhanced through the resonance response in the magnetic resonance imaging enhancement device 200, thereby improving the image quality.

[0067] Optionally, the resonant ring is embedded in an internal setting of the closed substrate. For example, the resonant ring can be embedded in the center position of the closed substrate, or the resonant ring can be embedded in other positions of the closed substrate that deviate from the center position. It should be noted that the specific position where the resonant ring is embedded in the closed substrate is not limited in the embodiments of the present application.

[0068] The above-mentioned magnetic resonance imaging enhancement device includes: a metamaterial array; the metamaterial array includes a plurality of periodically arranged metamaterial units, the metamaterial unit includes a closed substrate with a through hole and a resonant ring; the resonant ring is embedded in the closed substrate; the resonant ring is used to automatically detune the metamaterial array in the transmitting phase of magnetic resonance imaging, and to resonate in the receiving phase of magnetic resonance imaging, so as to improve the quality of magnetic resonance imaging. The magnetic resonance imaging enhancement device provided by the present application, in the MRI transmitting phase, the resonant ring uses the automatic detuning function to make the enhancement device exit the resonant state, so as to avoid interfering with the normal excitation process of the magnetic resonance imaging device; in the MRI receiving phase, the resonant response of the resonant ring and the resonator enables the enhancement device to enhance the radio frequency magnetic field signal emitted by the object under test, thereby achieving the enhancement of the MRI receiving signal, significantly improving the imaging signal-to-noise ratio, and thus improving the image quality.

[0069] In one embodiment, Figure 4 As shown, the resonant ring 1001 includes: a substrate material 10010, a metal wire 10011 and a varactor diode 10012;

[0070] The varactor diode 10012 is disposed on the metal line 10011 , and the metal line 10011 is embedded in the substrate material 10010 along a cross section of the substrate material 10010 .

[0071] The resonant ring may be a nonlinear metal resonant ring.

[0072] The width of the substrate material is 0.5 mm, the thickness is 0.035 mm, the material of the substrate material is a polymer material, and the capacitance of the varactor diode is 18 pF.

[0073] It should be noted that, by utilizing the rectifying effect of the varactor diode 10012 and the characteristic that the junction capacitance changes with the bias voltage at both ends, the resonant ring 1001 equipped with the varactor diode 10012 has the ability to automatically tune the resonant frequency as the excitation power of the external RF magnetic field changes. This adaptive tuning characteristic enables the metamaterial array 10 to resonate in the RF receiving stage of the magnetic resonance to enhance the RF magnetic field, and automatically detune in the RF transmitting stage of the magnetic resonance, thereby ensuring that the original working parameter settings of the MRI device remain unchanged, significantly improving the quality and efficiency of MRI imaging.

[0074] In one embodiment, Figure 5 As shown, the metamaterial unit 100 further includes a resonator 1002 , which is wound in a spiral shape along the outside of the closed substrate 1000 , and the resonator 1002 is used to make the metamaterial array 10 resonate.

[0075] The wire diameter of the resonator is 0.6 mm. The resonator may be a metal linear resonator. The number of turns of the resonator 1002 around the closed substrate 1000 may be 4.5.

[0076] It should be noted that, when the closed substrate 1000 is a circular ring, the resonator 1002 is a circular ring spiral, and the three-dimensional shape corresponding to the circular ring can be described by the following equation (1):

[0077]

[0078] Wherein, R and r are the main radius and tube radius of the closed base 1000, respectively, and the torus spiral is wound q times in the direction of the main radius of the closed base 1000, that is, the number of coils of the torus spiral along the outer path of the torus. The spiral is wound p times in the direction of the tube radius of the torus, that is, the number of rotations along the inner axis of the torus, and l is the length of the spiral.

[0079] In the embodiment of the present application, the magnetic resonance imaging enhancement device also includes a resonator, which can cause the metamaterial array to resonate to enhance the local radio frequency magnetic field and improve the signal-to-noise ratio of the magnetic resonance imaging.

[0080] In one embodiment, see Figure 2 The magnetic resonance imaging enhancement device 01 further includes: a substrate 20 , and the substrate 20 is bonded to the metamaterial array 10 .

[0081] In one embodiment, see Figure 2 , a plurality of slit patterns are arranged on the substrate 20 .

[0082] It should be noted that, in order to ensure that the metamaterial array 10 has the conformality to adapt to complex curved surfaces (curved surfaces of the object to be measured), the present application further introduces a substrate 20 with multiple slit patterns. By designing the slit pattern on the substrate 20, the original hard substrate 20 has the conformality of a quadratic surface, so that the metamaterial array 10 fixed on the substrate 20 can achieve precise fit with the complex curved surface (curved surface of the object to be measured), thereby improving the enhancement effect of imaging.

[0083] The objects to be tested may be bottle-shaped models of different shapes filled with aqueous solution, each having cylindrical, flat and spherical features.

[0084] In the embodiment of the present application, a plurality of slit patterns are provided on the substrate so that the substrate can substantially fit the object to be measured, thereby improving the imaging accuracy of the magnetic resonance imaging enhancement device.

[0085] In one embodiment, see Figure 2 The magnetic resonance imaging enhancement device 01 further includes: a bonding key 30 , which is used to connect the substrate 20 and the metamaterial array 10 .

[0086] The magnetic resonance imaging enhancement device with a bonding key provided in the present application enables the substrate and the metamaterial array to be bonded together, so that the metamaterial array can accurately obtain the radio frequency magnetic field signal reflected by the object under test collected by the substrate, thereby accurately enhancing the MRI receiving signal, significantly improving the imaging signal-to-noise ratio, and further improving the image quality.

[0087] In summary, the magnetic resonance imaging enhancement device provided by the present invention has a metamaterial structure with small size and thin thickness, and is combined with a flexible substrate that can be attached to complex curved surfaces, and has the advantages of compact structure, small size and good conformality. The overall magnetic resonance imaging signal-to-noise ratio is significantly improved, and the present invention provides strong technical support for high-quality medical diagnosis.

[0088] In one embodiment, as shown in FIG1 , a magnetic resonance imaging enhancement system is provided, the magnetic resonance imaging enhancement system comprising: a magnetic resonance imaging enhancement device, a subject to be measured, and a magnetic resonance imaging device as described in the above embodiments;

[0089] The magnetic resonance imaging enhancement device and the object to be measured are fitted together;

[0090] The magnetic resonance imaging enhancement device is used to automatically detune during the radio frequency transmission stage of the magnetic resonance imaging device to avoid affecting the excitation of the object to be measured; and to resonate and enhance the magnetic resonance signal generated by the object to be measured during the radio frequency receiving stage of the magnetic resonance imaging device.

[0091] In the embodiment of the present application, since a plurality of slit patterns are arranged on the substrate in the magnetic resonance imaging enhancement device, the magnetic resonance imaging enhancement device can be arranged to fit the object to be measured, so that the rays returned by the object to be measured can be accurately resonated and the image quality of the magnetic resonance imaging can be improved.

[0092] It should be noted that when performing magnetic resonance imaging, the magnetic resonance imaging device first transmits radio frequency pulses to the object under test through the magnetic resonance imaging enhancement device. In order to avoid interference with the normal excitation process of the magnetic resonance imaging device, the metamaterial array exits the resonant state through the automatic detuning function. After the object under test receives the radio frequency pulse, the metamaterial array enhances the radio frequency magnetic field signal emitted by the object under test, thereby enhancing the MRI receiving signal, significantly improving the imaging signal-to-noise ratio, and thus improving the image quality. During the entire magnetic resonance imaging process, the radio frequency magnetic field signal emitted by the object under test is enhanced through the resonant response in the magnetic resonance imaging enhancement device, thereby improving the image quality.

[0093] like Figure 6 The figure shows the experimental measurement results of the resonant response (reflection coefficient) of the magnetic resonance imaging enhancement device in the present application. The varactor diode in the magnetic resonance imaging enhancement device has a rectifying effect and the property that the junction capacitance changes with the bias voltage at both ends, so that the resonant ring equipped with the varactor diode has a nonlinear response to the external RF magnetic field excitation power. Furthermore, due to the coupling effect between the resonator and the resonant ring, and the coupling effect between multiple periodically arranged metamaterial units, the metamaterial array as a whole has a nonlinear response to the external RF magnetic field excitation power. See Figure 6 , showing the change curve between the resonant frequency and the reflection coefficient of the metamaterial array under different excitation powers. Under low excitation power (-30dBm), the reflection coefficient curve of the metamaterial array shows that the metamaterial array has a strong resonant response at the resonant frequency of 127 MHz; while under high excitation power (0 dBm), the reflection coefficient curve of the metamaterial array shows that the resonant frequency of the resonant ring 212 deviates from the original resonant frequency and the resonant response intensity decreases.

[0094] like Figure 7-Figure 9 As shown in the figure, the simulation results of the RF magnetic field enhancement multiples of the magnetic resonance imaging enhancement device in the present application are respectively shown under different test objects (for example, test objects with cylindrical, flat and spherical features). The simulation results show that the RF magnetic field is significantly enhanced in the region of interest near the metamaterial array, which verifies the effectiveness of the present invention.

[0095] It should be noted that Figure 7 Demonstrated the distribution of radio frequency magnetic field enhancement multiples of cylindrical metamaterial arrays. Figure 8 Demonstrated the distribution of radio frequency magnetic field enhancement multiples of planar metamaterial arrays. Fig. 9 The distribution of radio frequency magnetic field enhancement multiples of spherical metamaterial arrays is demonstrated.

[0096] like Fig.10 The figure shows the magnetic resonance imaging results obtained by applying the magnetic resonance imaging enhancement device provided by the present application. Under the condition that the object to be measured is a water solution bottle-shaped model with cylindrical, flat and spherical features, the experimental results show that the magnetic resonance imaging enhancement device achieves a signal-to-noise ratio enhancement factor of about 3.5 times in the region of interest near it, which further proves the significant effect of the magnetic resonance imaging enhancement device provided by the present application in practical applications.

[0097] Among them, see Fig.10 , the left column is the magnetic resonance imaging results of the object under test with a cylindrical shape, the middle column is the magnetic resonance imaging results of the object under test with a planar shape, and the right column is the magnetic resonance imaging results of the object under test with a spherical shape.

[0098] It should be understood that, although the various steps in the flowcharts involved in the above-mentioned embodiments are displayed in sequence according to the indication of the arrows, these steps are not necessarily executed in sequence according to the order indicated by the arrows. Unless there is a clear explanation in this article, the execution of these steps does not have a strict order restriction, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above-mentioned embodiments can include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily to be carried out in sequence, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

[0099] A person of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment method can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile memory and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. Non-relational databases may include distributed databases based on blockchains, etc., but are not limited to this. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, an artificial intelligence (AI) processor, etc., but are not limited to this.

[0100] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this application.

[0101] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A magnetic resonance imaging enhancement device, characterized in that: The magnetic resonance imaging enhancement device comprises: a metamaterial array; The metamaterial array includes a plurality of periodically arranged metamaterial units, wherein the metamaterial unit includes a closed substrate with a through hole and a resonant ring; the resonant ring is embedded in the closed substrate; The resonant ring is used to automatically detune the metamaterial array during the transmitting phase of magnetic resonance imaging, and to generate resonance during the receiving phase of magnetic resonance imaging, so as to improve the quality of magnetic resonance imaging.

2. The magnetic resonance imaging enhancement device according to claim 1, characterized in that: The resonant ring includes a substrate material, a metal wire and a varactor diode; The varactor diode is arranged on the metal wire, and the metal wire is embedded in the substrate material along the cross section of the substrate material.

3. The magnetic resonance imaging enhancement device according to claim 2, characterized in that: The metamaterial unit further includes: a resonator, the resonator being wound along an outer spiral of the closed substrate; The resonator is used to make the metamaterial array resonate.

4. The magnetic resonance imaging enhancement device according to claim 1 or 2, characterized in that: The magnetic resonance imaging enhancement device further includes: a substrate, and the substrate is bonded to the metamaterial array.

5. The magnetic resonance imaging enhancement device according to claim 4, characterized in that: A plurality of slit patterns are arranged on the substrate.

6. The magnetic resonance imaging enhancement device according to claim 4, characterized in that: The magnetic resonance imaging enhancement device further comprises: a bonding key, which is used to connect the substrate and the metamaterial array.

7. The magnetic resonance imaging enhancement device according to claim 1 or 2, characterized in that: The closed substrate is made of polymer material.

8. The magnetic resonance imaging enhancement device according to claim 1 or 2, characterized in that: The closed substrate comprises a torus-shaped substrate, the major radius of the torus-shaped substrate is 15 mm, and the tube radius of the torus-shaped substrate is 1.8 mm.

9. The magnetic resonance imaging enhancement device according to claim 3, characterized in that: The wire diameter of the resonator is 0.6 mm, the width of the substrate material is 0.5 mm, the thickness is 0.035 mm, and the capacitance of the varactor diode is 18 pF.

10. A magnetic resonance imaging enhancement system, characterized in that: The magnetic resonance imaging enhancement system comprises: an object to be measured, a magnetic resonance imaging device and a magnetic resonance imaging enhancement device as described in claims 1 to 9 above; The magnetic resonance imaging enhancement device and the object to be measured are arranged in close contact with each other; The magnetic resonance imaging enhancement device is used to automatically detune during the radio frequency transmission stage of the magnetic resonance imaging device to avoid affecting the excitation of the object to be measured; and is used to resonate and enhance the magnetic resonance signal generated by the object to be measured during the radio frequency reception stage of the magnetic resonance imaging device.

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