Tissue sample cutting and collecting device

Abstract

The invention provides a tissue sample cutting and collecting device which is provided with a cutting direction and comprises a hollow body, the two opposite sides, in the cutting direction, of the inner wall of the hollow body are the first side and the second side correspondingly, and the two ends, in the length direction, of the hollow body are the exposed end and the cutting end correspondingly. And the cutting end is provided with a cutting edge. According to the tissue sample cutting and collecting device, the cutting end of the hollow main body is vertically pressed into tissue to be sampled, the cutting wire is switched from an initial state to a cutting completion state, the cutting wire cuts the tissue entering the inner side of the hollow main body, and regular sampling of the tissue is achieved; the tension of the cutting wire can be adjusted, in the non-use state, the tension of the cutting wire can be lowered, it is avoided that the cutting wire is kept in the high-tension state for a long time, and the service life of the cutting wire is affected, the tension of the cutting wire is increased to the proper tension before use, and it is ensured that the cutting wire can smoothly cut tissue.

Description

Technical Field

[0001] The present invention relates to the technical field of tissue sample cutting and collecting, and in particular to a tissue sample cutting and collecting device. Background Art

[0002] In biomedical and scientific research, obtaining tissue samples is one of the key steps in experiments and analysis. Obtaining complete and standardized tissue samples is crucial for a variety of subsequent research applications, such as gene sequencing, tissue analysis, pathological research, and sample preservation.

[0003] Existing sampling tools have the following shortcomings in the sample organization process, making it difficult to meet the high requirements of scientific research applications for sample integrity and standardization:

[0004] The tools currently used mainly include surgical scissors, scalpels, puncture needles, etc. These tools often lack precise control over the cutting depth and shape, resulting in irregular shapes of cut samples and difficulty in standardizing the volume, which has an adverse effect on subsequent analysis. Especially when multiple sampling or comparative experiments are required, irregular samples will increase the error range of the experiment and affect the accuracy of the research results. In addition, traditional cutting tools will cause mechanical damage to the samples during contact with the tissue. Especially when using scissors, the surface of the sample is often squeezed or twisted, thereby destroying the cell structure and reducing the accuracy of the experiment. When cutting deep tissues, the operation process is complicated and it is difficult to ensure the integrity and consistency of the tissue samples. In addition, when transferring the sampled tissue, irregular tissue samples are prone to slipping, affecting the normal progress of the experiment.

[0005] Therefore, in order to solve the above problems, the present invention proposes a tissue sample cutting and collecting device with a regular shape of tissue samples and in which the tissue samples are not easy to slip during the transfer process. Summary of the invention

[0006] In order to solve the problems existing in the above-mentioned existing tissue sample cutting and collecting tools, the present invention provides a tissue sample cutting and collecting device.

[0007] According to one object of the present invention, the present invention provides a tissue sample cutting and collecting device, wherein the tissue sample cutting and collecting device is provided with a cutting direction, and comprises a hollow body, wherein two opposite sides of the inner wall of the hollow body in the cutting direction are respectively a first side and a second side, and two ends of the hollow body in the length direction are respectively an exposed end and a cutting end, and the cutting end is provided with a cutting blade;

[0008] A cutting wire with adjustable tension is arranged on the inner side of the hollow body close to the cutting end. The cutting wire is movably connected to the hollow body along the cutting direction through a guide assembly. A shielding assembly is arranged between the cutting wire and the hollow body. The cutting wire has at least two working states, namely an initial state and a cutting completion state. When the cutting wire is in the initial state, the cutting wire and the shielding assembly are both hidden in the first side inner wall of the hollow body. When the cutting wire is in the cutting completion state, the cutting wire is hidden in the second side inner wall of the hollow body, and the shielding assembly shields the cutting end of the hollow body.

[0009] Preferably, the shape of the hollow body in the cutting direction is square or circular, and the radial outer side of the hollow body gradually decreases in a manner close to the cutting end to form the cutting edge.

[0010] Preferably, the guide assembly is hidden in the inner wall of the hollow body;

[0011] A groove for accommodating the cutting wire and the shielding assembly is formed on a first side of the hollow body, and a groove for accommodating the cutting wire is formed on a second side of the hollow body.

[0012] Preferably, the guide assembly includes a lower slide, a lower slider, a connecting rod, an upper slider and an upper slide, the inner wall of the hollow body is provided with a lower slide on both sides perpendicular to the cutting direction, the lower slide is arranged along the cutting direction, the lower slide is movably connected with the lower slide, the cutting wire is connected between the lower sliders, the lower slider is connected with a connecting rod extending toward the exposed end, the connecting rod is connected with the upper slider, the side of the hollow body close to the exposed end is provided with an upper slide, the upper slide and the lower slide are parallel to each other, the upper slide has an upper slider as a movably connecting part, the end of the connecting rod is located on the outside of the hollow body, and the end of the connecting rod is connected by a handle.

[0013] Preferably, the lower slider is provided with a through hole in a manner perpendicular to the cutting direction, the end of the cutting wire is passed through the inner side of the through hole, and the cutting wire and the lower slider are connected by a ratchet structure.

[0014] Preferably, the shielding assembly includes a winding rod and a shielding member, the winding rod and the cutting wire are parallel to each other, the winding rod and the hollow body are connected by a rotating pair, and a coil spring is arranged between the winding rod and the hollow body, in the cutting direction, one end of the shielding member is connected to the winding rod, and the other end of the shielding member is connected to the cutting wire, and the shielding member is arranged to be suitable for winding around the outside of the winding rod.

[0015] Preferably, the exposed end is connected to a pushing component, and the pushing component is configured to move along the length direction of the hollow body to push the target tissue in the hollow body out through the cutting end.

[0016] Preferably, the ejection assembly and the exposed end are detachably connected.

[0017] Preferably, the ejection assembly includes a cover body, a push rod and a push piece, the cover body and the exposed end are connected by threads, the push rod is movably connected to the cover body along the length direction of the hollow body, the first end of the push rod is exposed to the outside of the cover body, the second end of the push rod is located on the inside of the cover body, the push piece is arranged at the second end of the push rod, and the outer periphery of the push piece is close to the inner wall of the hollow body.

[0018] Preferably, a transparent window is provided on the hollow body, and scales are provided on the transparent window along the length direction of the hollow body.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] The tissue sample cutting and collecting device vertically presses the cutting end of the hollow body into the tissue to be sampled, and switches the cutting wire from the initial state to the cutting completion state, so that the cutting wire cuts the tissue entering the inner side of the hollow body, thereby achieving regular sampling of the tissue, wherein the shielding component shields the tissue inside the hollow body to prevent the tissue from falling during the transfer process;

[0021] The tension of the cutting wire is adjustable. When not in use, the tension of the cutting wire can be lowered to prevent the cutting wire from maintaining a high tension state for a long time, which affects the service life of the cutting wire. Before use, adjust the cutting wire to an appropriate tension to ensure that the cutting wire can cut the tissue smoothly.

[0022] The present invention is further described below with reference to the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of an overall front section of one embodiment of a tissue sample cutting and collecting device according to the present invention;

[0024] Figure 2 This is a schematic diagram of the connection between the guide assembly and the hollow body of one embodiment of the tissue sample cutting and collecting device of the present invention;

[0025] Figure 3 It is a schematic top view of the initial state of the cutting wire of one embodiment of the tissue sample cutting and collecting device of the present invention;

[0026] Figure 4This is a top view of a handle of one embodiment of a tissue sample cutting and collecting device of the present invention when the cutting wire is in the initial state;

[0027] Figure 5 It is a top view schematic diagram of a state where the cutting wire of one embodiment of the tissue sample cutting and collecting device of the present invention is cut and completed;

[0028] Figure 6 This is a top view of a handle of one embodiment of a tissue sample cutting and collecting device of the present invention when the cutting wire is cut and completed;

[0029] Figure 7 This is a schematic diagram of a ratchet structure of one embodiment of a tissue sample cutting and collecting device according to the present invention;

[0030] Figure 8 This is a schematic diagram of the connection between the guide assembly and the hollow body of another embodiment of the tissue sample cutting and collecting device of the present invention. DETAILED DESCRIPTION

[0031] The following description is used to fully explain the present invention so that those skilled in the art can implement the present invention. The preferred embodiments described below are only examples, and those skilled in the art can think of other obvious variations. The basic principles of the present invention defined in the following description can be applied to other embodiments, variations, improvements, equivalents, and other technical solutions that do not deviate from the spirit and scope of the present invention.

[0032] See also Figure 1-8 The present invention provides a technical solution: a tissue sample cutting and collecting device, the tissue sample cutting and collecting device is provided with a cutting direction, comprising a hollow body 100, the inner wall of the hollow body 100 having two opposite sides in the cutting direction, namely a first side 100a and a second side 100b, the two ends of the hollow body 100 in the length direction are respectively an exposed end 101 and a cutting end 102, and the cutting end 102 is provided with a cutting blade 1021;

[0033] A cutting wire 200 with adjustable tension is arranged inside the hollow body 100 in a manner close to the cutting end 102. The cutting wire 200 is arranged to be movable along the cutting direction to cut the target tissue entering the inside of the hollow body 100. A shielding component 400 is arranged between the cutting wire 200 and the hollow body 100. The cutting wire 200 has at least two working states, namely, an initial state and a cutting completion state. When the cutting wire 200 is in the initial state, see Figure 3 and 4 The cutting wire 200 and the shielding assembly 400 are both hidden in the inner wall of the first side 100a of the hollow body 100. When the cutting wire 200 is in the cutting completion state, see Figure 5 and 6 The cutting wire 200 is hidden in the inner wall of the second side 100 b of the hollow body 100 , and the shielding assembly 400 shields the cutting end 102 of the hollow body 100 .

[0034] The tissue sample cutting and collecting device vertically presses the cutting end 102 of the hollow body 100 into the tissue to be sampled, and switches the cutting wire 200 from the initial state to the cutting completion state, so that the cutting wire 200 cuts the tissue entering the inner side of the hollow body 100, thereby achieving regular sampling of the tissue, wherein the shielding component 400 shields the tissue inside the hollow body 100 to prevent the tissue from falling during the transfer process;

[0035] The tension of the cutting wire 200 is adjustable. When not in use, the tension of the cutting wire 200 can be lowered to prevent the cutting wire 200 from maintaining a high tension state for a long time, which affects the service life of the cutting wire 200. Before use, the cutting wire 200 is adjusted to an appropriate tension to ensure that the cutting wire 200 can cut the tissue smoothly.

[0036] It should be noted that the cutting wire 200 can be an electric heating wire or a non-heating wire. When the cutting wire 200 is an electric heating wire, the cutting wire 200 is connected to an external heating device to heat it, thereby enabling the cutting wire 200 to cut the tissue.

[0037] The shape of the hollow body 100 in the cutting direction is square or circular.

[0038] The radial outer side of the hollow body 100 is gradually reduced in size toward the cutting end 102 to form the cutting edge 1021 .

[0039] A groove for accommodating the cutting wire 200 and the shielding assembly 400 is formed on the first side 100 a of the hollow body 100 , and a groove for accommodating the cutting wire 200 is formed on the second side 100 b of the hollow body 100 .

[0040] The cutting wire 200 is movably connected to the hollow body 100 through a guide assembly 300, and the guide assembly 300 is hidden in the inner wall of the hollow body 100. The inner wall of the hollow body 100 is provided with a lower slide 301 on both sides perpendicular to the cutting direction. The lower slide 301 is arranged along the cutting direction, and a lower slider 302 is movably connected in the lower slide 301. The cutting wire 200 is connected between the lower sliders 302.

[0041] In one embodiment, see Figure 2The lower slider 302 is connected with a connecting rod 303 extending toward the exposed end 101, and the connecting rod 303 is connected with an upper slider 305. An upper slide 304 is provided on the side of the hollow body 100 close to the exposed end 101. The upper slide 304 and the lower slide 301 are parallel to each other. The movable connecting member in the upper slide 304 has an upper slider 305. The end of the connecting rod 303 is located outside the hollow body 100, and the end of the connecting rod 303 is connected through a handle 306. Preferably, the handle 306, the connecting rod 303, the upper slider 305 and the lower slider 302 are connected as one piece.

[0042] In another embodiment, see Figure 8 A lower guide wheel 307 is provided at one end of the lower slide track 301 close to the second side 100b of the hollow body 100, and an upper guide wheel 308 is provided above the lower guide wheel 307. A flexible member 309 is connected to the lower slider 302, and the flexible member 309 is guided by the lower guide wheel 307 and the upper guide wheel 308. The end of the flexible member 309 passes through the outside of the hollow body 100, and the end of the flexible member 309 is connected through a handle 306.

[0043] The lower slider 302 is provided with a through hole 3021 in a manner perpendicular to the cutting direction, and the end of the cutting wire 200 is passed through the inner side of the through hole 3021. The cutting wire 200 and the lower slider 302 are connected by a ratchet structure 3022. Specifically, the end of the cutting wire 200 is provided with a ratchet lock along the length direction of the cutting wire 200, and the lower slider 302 is provided with a buckle matching the ratchet lock. When in use, the end of the cutting wire 200 can be pulled, and the ratchet structure 3022 on the cutting wire 200 can limit the cutting wire 200 and the lower slider 302 in one direction, thereby adjusting the tension of the cutting wire 200. The buckle can be detached from the ratchet lock by oscillating the buckle, thereby reducing the tension of the cutting wire 200 and separating the cutting wire 200 and the lower slider 302.

[0044] The shielding assembly 400 is disposed on the first side 100a of the cutting wire 200 facing the hollow body 100, and the shielding assembly 400 includes a reeling rod 401 and a shielding member 402. The reeling rod 401 and the cutting wire 200 are parallel to each other, the reeling rod 401 and the hollow body 100 are connected by a rotating pair, and a coil spring is disposed between the reeling rod 401 and the hollow body 100. In the cutting direction, one end of the shielding member 402 is connected to the reeling rod 401, and the other end of the shielding member 402 is connected to the cutting wire 200. The shielding member 402 is configured to be wound around the outside of the reeling rod 401. Preferably, the shielding member 402 is a mesh-shaped shielding member 402.

[0045] For further information, see Figure 1 The exposed end 101 is connected to a push-out assembly 500, and the push-out assembly 500 is configured to move along the length direction of the hollow body 100 to push the target tissue in the hollow body 100 through the cutting end 102. The push-out assembly 500 is added to solve the problem of the complexity of the traditional tissue sample extraction process. Specifically, after obtaining the sample, the traditional tool often needs manual operation to extract the sample, which is not only time-consuming and labor-intensive, but also easy to cause sample damage. For example, when using a puncture needle to cut deep tissue, the tissue may remain on the inner wall of the needle or the inner cavity of the tool, and it is easy to break or stick when it is taken out, affecting the integrity of the sample.

[0046] Furthermore, the ejection assembly 500 and the exposed end 101 are detachably connected.

[0047] Specifically, the ejection assembly 500 includes a cover body 501, a push rod 502 and a push piece 503. The cover body 501 and the exposed end 101 are detachably connected via threads. The push rod 502 is movably connected to the cover body 501 along the length direction of the hollow body 100. The first end of the push rod 502 is exposed to the outside of the cover body 501, and the second end of the push rod 502 is located on the inside of the cover body 501. The push piece 503 is arranged at the second end of the push rod 502, and the outer periphery of the push piece 503 is close to the inner wall of the hollow body 100.

[0048] The hollow body 100 is provided with a transparent window 103 , and the transparent window 103 is provided with scales 104 arranged along the length direction of the hollow body 100 .

[0049] The specific specifications of the hollow body 100 can be customized, such as a sampling space of 1 cm×1 cm.

[0050] In one embodiment, the hollow body 100 is made of medical grade 316L stainless steel, the outer size of the hollow body 100 is 1.2 cm×1.2 cm, the inner size of the hollow body 100 is 1 cm×1 cm, the total length of the hollow body 100 is 10 cm, and the wall thickness of the hollow body 100 is 1 mm;

[0051] The width of the upper slideway 304 and the lower slideway 301 is 2 mm, and the depth is 1 mm;

[0052] The handle 306 is made of medical-grade PP plastic, the lower slider 302 and the upper slider 305 are made of medical-grade PEEK material, the cutting wire 200 is made of medical-grade 316L stainless steel wire, and the diameter of the cutting wire 200 is 0.2 mm.

[0053] Directions:

[0054] S1. Preoperative preparation, including:

[0055] S11. Routine disinfection; S12. Check the connection of each component;

[0056] S2. Sampling steps, specifically including:

[0057] S21. Determine the sampling position; S22. Press the cutter vertically to press the cutting blade 1021 of the cutter into the tissue to be sampled, such as a depth of 1 cm, and the tissue enters the hollow tube; S23. Push the handle 306; S24. The handle 306 drives the cutting wire 200 to cut the bottom of the tissue through the connecting rod 303; S25. Remove the device; S26. Operate the push assembly 500 to separate the sample;

[0058] S3. Postoperative treatment, including:

[0059] S31. Clean and disinfect; S32. Inspect and maintain; S33. Store properly.

[0060] In summary, the tissue sample cutting and collecting device has the following advantages:

[0061] 1. Complete sampling in one go, with high efficiency;

[0062] 2. Accurate sample volume;

[0063] 3. Simple operation, reducing the difficulty of use;

[0064] 4. The cutting wound surface is neat and reduces tissue damage;

[0065] 5. Simple structure and easy maintenance.

[0066] The embodiments described above are only used to illustrate the technical ideas and features of the present invention, and their purpose is to enable technicians in this field to understand the contents of the present invention and implement them accordingly. The patent scope of the present invention cannot be limited only by this embodiment, that is, any equivalent changes or modifications made according to the spirit disclosed by the present invention still fall within the patent scope of the present invention.

Claims

1. A tissue sample cutting and collecting device, wherein a cutting direction is provided on the tissue sample cutting and collecting device, characterized in that: It comprises a hollow body (100), wherein two opposite sides of the inner wall of the hollow body (100) in the cutting direction are respectively a first side (100a) and a second side (100b), and two ends of the hollow body (100) in the length direction are respectively an exposed end (101) and a cutting end (102), and the cutting end (102) is provided with a cutting blade (1021); A cutting wire (200) with adjustable tension is arranged on the inner side of the hollow body (100) in a manner close to the cutting end (102); the cutting wire (200) is movably connected to the hollow body (100) along the cutting direction via a guide assembly (300); a shielding assembly (400) is arranged between the cutting wire (200) and the hollow body (100); the cutting wire (200) has at least two working states, namely an initial state and a cutting completion state. When the cutting wire (200) is in the initial state, the cutting wire (200) and the shielding assembly (400) are both hidden in the inner wall of the first side (100a) of the hollow body (100); when the cutting wire (200) is in the cutting completion state, the cutting wire (200) is hidden in the inner wall of the second side (100b) of the hollow body (100), and the shielding assembly (400) shields the cutting end (102) of the hollow body (100).

2. A tissue sample cutting and collecting device according to claim 1, characterized in that: The shape of the hollow body (100) in the cutting direction is square or circular, and the radial outer side of the hollow body (100) gradually decreases in size in a manner close to the cutting end (102) to form the cutting edge (1021).

3. A tissue sample cutting and collecting device according to claim 1, characterized in that: The guide assembly (300) is hidden in the inner wall of the hollow body (100); A first side (100a) of the hollow body (100) is provided with a groove for accommodating the cutting wire (200) and the shielding assembly (400), and a second side (100b) of the hollow body (100) is provided with a groove for accommodating the cutting wire (200).

4. A tissue sample cutting and collecting device according to claim 1, characterized in that: The guide assembly (300) comprises a lower slideway (301), a lower slider (302), a connecting rod (303), an upper slider (305) and an upper slideway (304); the inner wall of the hollow body (100) is provided with lower slideways (301) on both sides perpendicular to the cutting direction; the lower slideway (301) is provided along the cutting direction; the lower slider (302) is movably connected in the lower slideway (301); the cutting wire (200) is connected between the lower sliders (302); the lower slider (302) is connected with a slideway (305) toward the exposed end ( A connecting rod (303) extends from one side of the hollow body (100), an upper slider (305) is connected to the connecting rod (303), an upper slideway (304) is arranged on one side of the hollow body (100) close to the exposed end (101), the upper slideway (304) and the lower slideway (301) are parallel to each other, an upper slider (305) is provided in the movable connecting piece in the upper slideway (304), the end of the connecting rod (303) is located on the outside of the hollow body (100), and the ends of the connecting rod (303) are connected via a handle (306).

5. A tissue sample cutting and collecting device according to claim 1, characterized in that: The lower slider (302) is provided with a through hole (3021) in a manner perpendicular to the cutting direction, the end of the cutting wire (200) is passed through the inner side of the through hole (3021), and the cutting wire (200) and the lower slider (302) are connected via a ratchet structure (3022).

6. A tissue sample cutting and collecting device according to claim 1, characterized in that: The shielding assembly (400) comprises a winding rod (401) and a shielding member (402); the winding rod (401) and the cutting wire (200) are parallel to each other; the winding rod (401) and the hollow body (100) are connected via a rotating pair; and a coil spring is arranged between the winding rod (401) and the hollow body (100); in the cutting direction, one end of the shielding member (402) is connected to the winding rod (401), and the other end of the shielding member (402) is connected to the cutting wire (200); the shielding member (402) is arranged to be wound around the outside of the winding rod (401).

7. A tissue sample cutting and collecting device according to claim 1, characterized in that: The exposed end (101) is connected to a pushing assembly (500), and the pushing assembly (500) is configured to move along the length direction of the hollow body (100) to push the target tissue in the hollow body (100) out through the cutting end (102).

8. A tissue sample cutting and collecting device according to claim 7, characterized in that: The ejection assembly (500) and the exposed end (101) are detachably connected.

9. A tissue sample cutting and collecting device according to claim 8, characterized in that: The ejection assembly (500) comprises a cover body (501), a push rod (502) and a push piece (503); the cover body (501) and the exposed end (101) are connected by threads; the push rod (502) is movably connected to the cover body (501) along the length direction of the hollow body (100); the first end of the push rod (502) is exposed to the outside of the cover body (501); the second end of the push rod (502) is located on the inside of the cover body (501); the push piece (503) is arranged at the second end of the push rod (502); and the outer periphery of the push piece (503) is close to the inner wall of the hollow body (100).

10. The tissue sample cutting and collecting device according to claim 1, characterized in that: The hollow body (100) is provided with a transparent window (103), and the transparent window (103) is provided with scales (104) arranged along the length direction of the hollow body (100).

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