Sampling device for sampling direct ionization and use method thereof

Abstract

The invention belongs to the field of ionization sampling, and particularly relates to a sampling device for direct ionization of sampling and a using method thereof.The sampling device comprises a device shell, a small air pump, a third magnetic plate, a filter screen plate and a dehumidification screen plate, a protective door is installed on the device shell, and a fixing plate is fixedly welded in the device shell; a first air inlet pipe is fixedly welded to the top of the device shell, a first treatment box is connected to the bottom end of the first air inlet pipe, a second air inlet pipe is connected to the bottom end of the first treatment box, a fixing pipe is connected to the bottom end of the second air inlet pipe, and an air guide pipe is connected to one end of the fixing pipe. The problems that an existing sampling device for sampling and direct ionization is low in practicability and automation degree, samples cannot be automatically fed and detected, and meanwhile used sample containing vessels cannot be automatically cleaned and dried, so that workers need to manually clean, dry and feed and detect, and the working efficiency is high are solved. The working efficiency is low; and the labor intensity is high.

Description

Technical Field

[0001] The invention relates to the field of ionization sampling, and in particular to a sampling device for direct ionization sampling and a use method thereof. Background Art

[0002] Due to the characteristics of high sensitivity, high precision, and high throughput, mass spectrometers play an important role in the analysis of complex mixtures such as biological tissues, body fluids, and environmental samples. Mass spectrometers can be used to detect the vast majority of compounds in the sample to be tested, thereby achieving structural identification of the target compound, quantitative analysis of low-level drugs and biomarkers in the body, etc. However, during the operation of the mass spectrometer, it is necessary to collect, store, and inject the samples to be tested, which has problems such as complex operation and great influence of human factors, and cannot meet the requirements of fast, efficient, and environmentally friendly analysis. The direct ionization technology developed in recent years can analyze samples quickly and non-destructively, and is therefore widely used in mass spectrometry analysis.

[0003] However, there are some problems in the actual working process of the existing sampling devices for direct sampling ionization. For example, the mass spectrometry sampling and ionization device and method for direct sample extraction and ionization with publication number CN103048378B can realize the direct extraction and ionization of liquid samples during the working process, but its practicality and automation level are low, and it is not possible to automatically load and detect the samples, and it is not possible to automatically clean and dry the sample placement containers after use. Therefore, the staff needs to manually clean, dry and load the inspection work, which has low work efficiency and high labor intensity, and it is very easy to cause errors in subsequent detection due to operational errors; and during the working process, it is not possible to filter and dehumidify the sheath gas to be used, so the dust, impurities and moisture in the sheath gas can easily affect the accuracy of subsequent detection results. Therefore, it is necessary to provide a sampling device for direct sampling ionization and a method for using it to meet the needs of users. Summary of the invention

[0004] In view of the problems existing in the existing sampling device for direct ionization of samples and the use method thereof, the present invention is proposed.

[0005] To solve the above technical problems, according to one aspect of the present invention, the present invention provides the following technical solutions: a sampling device for direct ionization of samples, comprising a device housing, a small air pump, a third magnetic plate, a filter plate and a dehumidification screen plate, a protective door is installed on the device housing, a fixing plate is welded and fixed inside the device housing, a first air inlet pipe is welded and fixed to the top of the device housing, the bottom end of the first air inlet pipe is connected to a first processing box, the bottom end of the first processing box is connected to a second air inlet pipe, the bottom end of the second air inlet pipe is connected to a fixed pipe, one end of the fixed pipe is connected to an air guide pipe, the end of the air guide pipe is fixedly connected to a sleeve, the end of the sleeve is bolted to the inlet end of a mass spectrometer, a capillary is fixedly connected inside the fixed pipe, and a ring is fixedly installed inside the fixed pipe. shaped electrode, the annular electrode sleeve is arranged on the capillary, the fixed tube is fixedly connected with the first liquid guide tube, the side end of the first liquid guide tube is connected with the second liquid guide tube, the second liquid guide tube is fixedly connected to the side end of the device shell, the bottom end of the first liquid guide tube is connected with the third liquid guide tube, the top of the first liquid guide tube is threadedly connected with a threaded rod, the bottom end of the threaded rod is rotatably connected with a sealing ring, a multi-functional workbench is installed at the bottom of the device shell, an automatic processing component is installed on the fixed plate, a third air inlet pipe is flange-connected to the small air pump, one end of the third air inlet pipe is fixedly connected to the side end of the device shell, the bottom end of the third air inlet pipe is connected with a second processing box, the bottom end of the second processing box is connected with a fourth air inlet pipe, and the fourth air inlet pipe is fixedly connected to the fixed plate.

[0006] As a preferred solution of the present invention, the inner diameter of the air guide tube and the inner diameter of the third liquid guide tube are both larger than the diameter of the fixed tube, the fixed tube is arranged in the middle part of the fixed tube, the annular electrodes are equidistantly distributed in the fixed tube, the threaded rods are symmetrically distributed on both sides of the sealing ring, the sealing ring is slidably connected in the first liquid guide tube, the sealing ring is sleeved on the capillary tube, the outer wall of the sealing ring is in contact with the inner wall of the first liquid guide tube, and the inner wall of the sealing ring is in contact with the outer wall of the capillary tube.

[0007] As a preferred solution of the present invention, the multifunctional workbench comprises a first hydraulic rod, the bottom end of the first hydraulic rod is fixedly mounted on the inner bottom end surface of the device housing, the top end of the first hydraulic rod is fixedly connected with a support plate, the bottom end surface of the support plate is fixedly mounted with a first servo motor, a turntable and a first limit plate are welded and fixed on the output shaft of the first servo motor, a lever is welded and fixed on the turntable, a connecting shaft is rotatably connected with the support plate, a second limit plate is welded and fixedly mounted on the bottom end of the connecting shaft, a limit slot is provided on the second limit plate, a rotating plate is welded and fixedly mounted on the top end of the connecting shaft, four first hydraulic rods are arranged, and the four first hydraulic rods are evenly distributed around the bottom of the support plate, the side end surface of the first limit plate is fitted with the side end surface of the second limit plate, four limit slots are arranged, and the four limit slots are respectively arranged at equal angles on the second limit plate, the bottom end surface of the rotating plate is fitted with the top end surface of the support plate, and the top end of the connecting shaft is fixed to the bottom middle part of the rotating plate.

[0008] As a preferred solution of the present invention, a material storage frame is bolted to the top surface of the rotating plate, a through groove is penetrated through the rotating plate, a first magnetic plate is slidably connected in the through groove, a first material discharge barrel and a second material discharge barrel are welded and fixed to the support plate, a second hydraulic rod is fixedly installed at the bottom of the first material discharge barrel and the bottom of the second material discharge barrel, a second magnetic plate is fixedly connected to the top of the second hydraulic rod, a sealing ring is fixedly connected to the first magnetic plate and the second magnetic plate, a bottom side end of the first material discharge barrel and a bottom side end of the second material discharge barrel are fixedly installed Both ends are fixedly connected with a rubber tube, the other end of the rubber tube is fixedly connected with a material guide tube, the material guide tube is welded and fixed to the bottom side end of the device shell, four storage frames are provided, and the four storage frames are distributed on the rotating plate at equal angles, the storage frames correspond to the through grooves one by one, the diameter of the through grooves, the inner diameter of the storage frames and the inner diameter of the first discharge barrel are equal, the inner wall of the storage frame fits with the outer wall of the sealing ring, the shape and size of the first discharge barrel are the same as those of the second discharge barrel, and the shape and size of the first magnetic plate are the same as those of the second magnetic plate.

[0009] As a preferred solution of the present invention, the automatic processing component includes a second servo motor, the second servo motor is welded and fixed on the top surface of the fixed plate, a first driving gear is welded and fixed on the output shaft of the second servo motor, one side of the first driving gear is meshed and connected with the second driving gear, the other side of the first driving gear is meshed and connected with the third driving gear, a first transfer frame is welded and fixed on the second driving gear, the first transfer frame is rotatably connected with a first connecting pipe through a sealed bearing, a first through hole and a second through hole are penetrated through the first connecting pipe, a first driven gear is welded and fixed on the top of the first connecting pipe, the first driven gear is meshed and connected with a first internal gear, the top of the first internal gear is welded and fixed on the bottom surface of the fixed plate, a flexible brush is fixedly connected to the first connecting pipe, a small water pump is installed and fixed on the bottom surface of the fixed plate, a water inlet pipe is flange-connected to the small water pump, one end of the water inlet pipe is fixedly connected to the side end of the device housing, and the bottom end of the water inlet pipe is rotatably connected to the top center of the first transfer frame through a sealed bearing.

[0010] As a preferred solution of the present invention, wherein: the shape and size of the second driving gear are the same as the shape and size of the third driving gear, the first connecting tubes are distributed at equal angles on the first transfer frame, the first through holes are symmetrically distributed on both sides of the top of the first connecting tube, four groups of second through holes are arranged, the four groups of second through holes are distributed at equal angles on the first connecting tube, each group of second through holes is equidistantly distributed on the first connecting tube, the first connecting tube corresponds one-to-one to the first driven gear, and the second through holes are alternately distributed with the flexible brushes.

[0011] As a preferred scheme of the present invention, wherein: a second transfer frame is welded and fixed on the third driving gear, a rubber plate is fixedly connected to the bottom end surface of the first transfer frame and the bottom end surface of the second transfer frame, the second transfer frame is rotatably connected to the second connecting pipe through a sealed bearing, the shape and size of the first transfer frame are the same as those of the second transfer frame, the diameter of the first transfer frame is larger than the diameter of the storage frame, a third through hole and a fourth through hole are penetrated through the second connecting pipe, a second driven gear is welded and fixed on the top end of the second connecting pipe, a second driven gear is meshed and connected with a second internal gear, the top end of the second internal gear is welded and fixed on the bottom end surface of the fixed plate, the shape and size of the first connecting pipe are the same as those of the second connecting pipe, the second connecting pipes are equiangularly distributed on the second transfer frame, the second connecting pipe corresponds one to one to the second driven gear, and the bottom end of the fourth intake pipe is rotatably connected to the top of the second transfer frame through a sealed bearing.

[0012] As a preferred solution of the present invention, the shape and size of the second processing box are the same as those of the first processing box, a positioning rod is welded and fixed to the side end surface of the first processing box and the side end surface of the second processing box, a return spring is welded and fixed inside the positioning rod, a stopper is welded and fixed to the other end of the return spring, the stopper is slidably connected to the positioning rod, a positioning groove is penetrated through the third magnetic plate, the positioning rod is slidably connected to the positioning groove, the upper and lower sides of the third magnetic plate are provided with card slots, the return spring is symmetrically distributed on both sides of the positioning rod, the return spring corresponds to the stopper one by one, the end cross-section of the stopper is a right-angled trapezoid, and the length of the positioning rod is greater than the thickness of the third magnetic plate.

[0013] As a preferred scheme of the present invention, wherein: the side ends of the filter plate and the side ends of the dehumidification screen plate are fixedly connected with magnetic blocks, the magnetic blocks are snap-connected in the card slots, the magnetic blocks are magnetically adsorbed and connected to the third magnetic plate, the filter plate is provided with a collecting slot, the collecting slots are distributed at equal angles on the filter plate, electric heating tubes are equidistantly installed on the inner wall of the first processing box and the inner wall of the second processing box, the inner wall of the first air intake pipe and the inner wall of the third air intake pipe are both connected with connecting rings with bearings, the inner wall of the connecting ring is welded and fixed with guide blades, the guide blade is welded and fixed with a rotating shaft, the bottom end of the rotating shaft is fixedly connected with a rubber scraper, the bottom end surface of the rubber scraper is in contact with the top end surface of the filter plate, a feed pipe is welded and fixed on the fixed plate, an electromagnetic valve is installed on the feed pipe, and a fourth magnetic plate is magnetically adsorbed and connected to the top end surface of the feed pipe.

[0014] A method for using a sampling device for direct ionization of samples comprises the following steps:

[0015] S1: When ionization sampling is performed on liquid samples, the liquid sample to be tested is transported to the multifunctional workbench through the feed pipe; when ionization sampling is performed on solid samples, the staff transports the sample to the multifunctional workbench by opening the protective door on the device housing;

[0016] S2: Use the multifunctional workbench and automatic processing components to automatically complete the cleaning, drying, testing and subsequent unloading of utensils;

[0017] S3: After the sample to be tested is transported to the multifunctional workbench, ensure that the sample is in contact with the sampling port at the bottom of the capillary;

[0018] S4: Deliver sheath gas into the fixed tube. When the sheath gas is ejected at high speed at the outlet of the air guide tube, a micro-vacuum environment can be formed at the top outlet of the capillary tube, providing a pressure gradient for extracting liquid samples, which is used to assist in extracting samples from the sampling port at the bottom of the capillary tube.

[0019] S5: using each annular electrode on the capillary to form a high voltage to ionize the sample, electrospray ionization occurs under the action of the high voltage to generate sample ions, which are transported to the mass spectrometer through the mass spectrometer inlet on the sleeve for detection and analysis;

[0020] S6: When the sample is solid, the solvent is sprayed on the solid surface through the first liquid guide tube and the third liquid guide tube to perform liquid-solid extraction, and then extraction and ionization are performed through the same operation, and subsequent detection and analysis are performed.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] 1. The present invention is provided with a multifunctional workbench, and the height of the supporting plate and the rotating plate can be conveniently adjusted by using the first hydraulic rod, so that each material storage frame can be pushed to move to a suitable position, thereby ensuring the convenience of subsequent sampling work; and the lever on the turntable and the second limit plate on the connecting shaft can drive the rotating plate to rotate intermittently, and each rotation is 90°, thereby driving the four material storage frames to automatically and stably switch positions, thereby driving the four material storage frames to automatically and intermittently move to the cleaning, drying, loading and testing positions, ensuring the convenience and efficiency of subsequent automated sampling and ionization work, effectively improving the automation degree of the sampling device, and increasing the diversity of use of the sampling device.

[0023] 2. The present invention is provided with an automatic processing component. By utilizing the intermittent movement of the four material storage frames, the four material storage frames can be moved one by one to the position directly below the first transfer frame and the position directly below the second transfer frame. By utilizing the meshing drive of the first active gear, in cooperation with the first driven gear and the first internal gear, each of the first connecting tubes can be driven to automatically rotate during the revolution, thereby automatically and efficiently performing all-round cleaning treatment on the used material storage frames. Similarly, by utilizing the revolution and rotation of each second connecting tube, the cleaned material storage frames can be automatically and efficiently performed all-round drying treatment, thereby ensuring the convenience and efficiency of the subsequent repeated use of the material storage frames, effectively improving the working efficiency of the sampling device, and at the same time preventing dust, impurities or moisture attached to the material storage frames from affecting the accuracy of subsequent sampling and detection results.

[0024] 3. The present invention is provided with a first processing box and a second processing box. The filter plate and the dehumidification mesh plate in the first processing box can be used to filter and dehumidify the sheath gas. At the same time, the temperature of the sheath gas can be adjusted according to actual needs to prevent dust, impurities or moisture in the sheath gas from affecting the accuracy of subsequent sampling and detection results. Similarly, the filter plate and the dehumidification mesh plate in the second processing box can be used to filter and dehumidify the drying gas, thereby improving the efficiency of subsequent drying work and avoiding internal contamination of the storage frame to ensure the accuracy of subsequent detection results.

[0025] 4. The present invention is provided with a rubber scraper and a positioning rod. During the transportation of the gas inside the first processing box and the second processing box, the guide fan blades can drive the rubber scraper on the rotating shaft to rotate automatically, so that the dust and impurities filtered on the filter plate can be moved to the collection tank for automatic collection, thereby avoiding blockage of the filter plate during long-term operation, which affects the stability of subsequent gas transportation. And the positioning rod and the block cooperate with the third magnetic plate and the magnetic block to conveniently complete the disassembly and installation of the filter plate and the dehumidification screen plate, thereby ensuring the convenience and efficiency of the subsequent cleaning and replacement of the filter plate and the dehumidification screen plate, thereby ensuring the stability of the filter plate and the dehumidification screen plate in subsequent long-term working conditions, thereby increasing the diversity and convenience of the sampling device. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the present invention will be described in detail below in combination with the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0027] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the present invention;

[0028] Figure 2 It is a schematic diagram of the connection structure of the threaded rod and the sealing ring of the present invention;

[0029] Figure 3 It is a schematic diagram of the connection structure between the second connecting pipe and the third through hole of the present invention;

[0030] Figure 4 It is a schematic diagram of the connection structure between the magnetic block and the filter plate of the present invention;

[0031] Figure 5 It is a schematic diagram of the main cross-sectional structure of the housing of the device of the present invention;

[0032] Figure 6 The present invention Figure 5 The enlarged structural diagram at A in the middle;

[0033] Figure 7 It is a schematic diagram of the side cross-section structure of the first liquid catheter of the present invention;

[0034] Figure 8 It is a schematic diagram of the main cross-sectional structure of the first liquid catheter of the present invention;

[0035] Fig. 9 It is a schematic diagram of the side section structure of the support plate of the present invention;

[0036] Fig.10 is a bottom view structural diagram of the second limiting plate of the present invention;

[0037] Fig.11 It is a schematic diagram of the top view of the material storage frame of the present invention;

[0038] Fig.12 This is a bottom view of the structure of the fixing plate of the present invention;

[0039] Fig.13 is a schematic diagram of the top view of the structure of the first driving gear of the present invention;

[0040] Fig.14 It is a schematic diagram of the side sectional structure of the first transfer frame of the present invention;

[0041] Fig.15 is a schematic diagram of a top-sectional structure of a first connecting pipe of the present invention;

[0042] Fig.16 It is a schematic diagram of the main cross-sectional structure of the first processing box of the present invention;

[0043] Fig.17 The present invention Fig.16 The enlarged structural diagram at B in the middle;

[0044] Fig.18 This is a schematic diagram of the top view of the electric heating tube of the present invention;

[0045] Fig.19 1. It is a schematic diagram of the top view of the rubber scraper rod of the present invention;

[0046] Fig. 20 It is a schematic diagram of the top view structure of the connecting ring of the present invention;

[0047] Fig.21 It is a schematic diagram of the main cross-sectional structure of the second processing box of the present invention.

[0048] In the figure: 1, device housing; 2, protective door; 3, fixed plate; 4, first air inlet pipe; 5, first processing box; 6, second air inlet pipe; 7, fixed pipe; 8, air guide pipe; 9, sleeve; 10, mass spectrometer inlet end; 11, capillary; 12, ring electrode; 13, first liquid guide pipe; 14, second liquid guide pipe; 15, third liquid guide pipe; 16, threaded rod; 17, sealing ring; 18, multifunctional workbench; 1801, first hydraulic rod; 1802, support plate; 1803, first servo motor; 1804, turntable; 1805 , first limit plate; 1806, lever; 1807, connecting shaft; 1808, second limit plate; 1809, limit slot; 1810, rotating plate; 1811, material storage frame; 1812, through slot; 1813, first magnetic plate; 1814, sealing ring; 1815, first discharge barrel; 1816, second hydraulic rod; 1817, second magnetic plate; 1818, rubber tube; 1819, material guide tube; 1820, second discharge barrel; 19, automatic processing component; 1901, second servo motor; 1902, first main driving gear; 1903, second driving gear; 1904, first transfer frame; 1905, rubber plate; 1906, first connecting pipe; 1907, first through hole; 1908, second through hole; 1909, first driven gear; 1910, first internal gear; 1911, flexible brush; 1912, small water pump; 1913, water inlet pipe; 1914, third driving gear; 1915, second transfer frame; 1916, second connecting pipe; 1917, third through hole; 1918, fourth through hole; 1919, second driven gear Gear; 1920, second internal gear; 20, small air pump; 21, third air inlet pipe; 22, second processing box; 23, fourth air inlet pipe; 24, positioning rod; 25, return spring; 26, block; 27, third magnetic plate; 28, positioning groove; 29, card slot; 30, magnetic block; 31, filter plate; 32, collecting groove; 33, dehumidification mesh plate; 34, electric heating tube; 35, connecting ring; 36, guide fan blade; 37, rotating shaft; 38, rubber scraper; 39, feed pipe; 40, solenoid valve; 41, fourth magnetic plate. DETAILED DESCRIPTION

[0049] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0050] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0051] Secondly, the present invention is described in detail with reference to schematic diagrams. When describing the embodiments of the present invention in detail, for the sake of convenience, the cross-sectional diagrams showing the device structure will not be partially enlarged according to the general scale, and the schematic diagrams are only examples, which should not limit the scope of protection of the present invention. In addition, in actual production, the three-dimensional dimensions of length, width and depth should be included.

[0052] Example

[0053] In order to make the objectives, technical solutions and advantages of the present invention more clear, the embodiments of the present invention will be further described in detail below with reference to the accompanying drawings.

[0054] like Figure 1-21 As shown, a sampling device for direct ionization of samples comprises a device housing 1, a small air pump 20, a third magnetic plate 27, a filter plate 31 and a moisture removal screen plate 33, a protective door 2 is installed on the device housing 1, a fixing plate 3 is welded and fixed inside the device housing 1, a first air inlet pipe 4 is welded and fixed on the top of the device housing 1, the bottom end of the first air inlet pipe 4 is connected to a first processing box 5, the bottom end of the first processing box 5 is connected to a second air inlet pipe 6, the bottom end of the second air inlet pipe 6 is connected to a fixing pipe 7, and the fixing One end of the tube 7 is connected to an air guide tube 8, the end of the air guide tube 8 is fixedly connected to a sleeve 9, the end of the sleeve 9 is bolted to the inlet end 10 of the mass spectrometer, a capillary 11 is fixedly connected in the fixed tube 7, an annular electrode 12 is fixedly installed in the fixed tube 7, the annular electrode 12 is sleeved on the capillary 11, a first liquid guide tube 13 is fixedly connected to the fixed tube 7, the side end of the first liquid guide tube 13 is connected to the second liquid guide tube 14, the second liquid guide tube 14 is fixedly connected to the side end of the device housing 1, and the first guide tube 13 is fixedly connected to the second liquid guide tube 14. The bottom end of the liquid tube 13 is connected to a third liquid guide tube 15, the top of the first liquid guide tube 13 is threadedly connected to a threaded rod 16, the bottom end of the threaded rod 16 is rotatably connected to a sealing ring 17, a multifunctional workbench 18 is installed at the bottom of the device housing 1, an automatic processing component 19 is installed on the fixed plate 3, a third air inlet pipe 21 is flange-connected to the small air pump 20, one end of the third air inlet pipe 21 is fixedly connected to the side end of the device housing 1, the bottom end of the third air inlet pipe 21 is connected to a second processing box 22, the bottom end of the second processing box 22 is connected to a fourth air inlet pipe 23, and the fourth air inlet pipe 23 is fixedly connected to the fixed plate 3. By utilizing the cooperation of the multifunctional workbench 18 and the automatic processing component 19, the cleaning, drying, testing and subsequent unloading of the sample placement vessel can be automatically completed, thereby ensuring the convenience and efficiency of the subsequent automated sampling and ionization work, effectively improving the automation degree and work efficiency of the sampling device, and avoiding the contamination of the sample, thereby improving the accuracy of the subsequent sampling and detection results.

[0055] In this embodiment, the inner diameter of the air guide tube 8 and the inner diameter of the third liquid guide tube 15 are both larger than the diameter of the fixed tube 7. The fixed tube 7 is arranged in the middle part of the fixed tube 7. The annular electrodes 12 are equidistantly distributed in the fixed tube 7. The threaded rods 16 are symmetrically distributed on both sides of the sealing ring 17. The sealing ring 17 is slidably connected in the first liquid guide tube 13. The sealing ring 17 is sleeved on the capillary 11. The outer wall of the sealing ring 17 is in contact with the inner wall of the first liquid guide tube 13, and the inner wall of the sealing ring 17 is in contact with the outer wall of the capillary 11. The various annular electrodes 12 can form a stable high voltage, thereby ensuring the stability of the subsequent ionization work of the sample.

[0056] In this embodiment, the multifunctional workbench 18 includes a first hydraulic rod 1801, the bottom end of the first hydraulic rod 1801 is fixedly mounted on the inner bottom end surface of the device housing 1, the top end of the first hydraulic rod 1801 is fixedly connected to a support plate 1802, the bottom end surface of the support plate 1802 is fixedly mounted with a first servo motor 1803, a turntable 1804 and a first limit plate 1805 are welded and fixed on the output shaft of the first servo motor 1803, a lever 1806 is welded and fixed on the turntable 1804, a connecting shaft 1807 is rotatably connected to the support plate 1802, a second limit plate 1808 is welded and fixed to the bottom end of the connecting shaft 1807, a limit slot 1809 is provided on the second limit plate 1808, and the top end of the connecting shaft 1807 is welded and fixed. A rotating plate 1810 is fixed, four first hydraulic rods 1801 are provided, and the four first hydraulic rods 1801 are evenly distributed around the bottom of the support plate 1802, the side end surface of the first limiting plate 1805 is fitted with the side end surface of the second limiting plate 1808, four limiting grooves 1809 are provided, and the four limiting grooves 1809 are respectively on the second limiting plate 1808 at equal angles, the bottom end surface of the rotating plate 1810 is fitted with the top end surface of the support plate 1802, the top end of the connecting shaft 1807 is fixed to the middle part of the bottom of the rotating plate 1810, and a storage frame 1811 is bolted on the top surface of the rotating plate 1810, and a through groove 1812 is opened through the rotating plate 1810, and the first magnetic plate 181 is slidably connected in the through groove 1812 3. A first material discharge barrel 1815 and a second material discharge barrel 1820 are welded and fixed on the support plate 1802. A second hydraulic rod 1816 is installed and fixed on the bottom of the first material discharge barrel 1815 and the bottom of the second material discharge barrel 1820. A second magnetic plate 1817 is fixedly connected to the top of the second hydraulic rod 1816. A sealing ring 1814 is fixedly connected to the first magnetic plate 1813 and the second magnetic plate 1817. A rubber tube 1818 is fixedly connected to the bottom side end of the first material discharge barrel 1815 and the bottom side end of the second material discharge barrel 1820. The other end of the rubber tube 1818 is fixedly connected to a material guide pipe 1819. The material guide pipe 1819 is welded and fixed to the bottom side end of the device housing 1. The storage frame 1811 is provided with four, four storage The material frames 1811 are distributed at equal angles on the rotating plate 1810. The material storage frames 1811 correspond to the through grooves 1812 one by one. The diameter of the through grooves 1812, the inner diameter of the material storage frame 1811 and the inner diameter of the first material discharge barrel 1815 are equal. The inner wall of the material storage frame 1811 fits the outer wall of the sealing ring 1814. The shape and size of the first material discharge barrel 1815 are the same as those of the second material discharge barrel 1820. The shape and size of the first magnetic plate 1813 are the same as those of the second magnetic plate 1817. The first hydraulic rod 1801 can be used to conveniently adjust the height of the support plate 1802 and the rotating plate 1810, thereby pushing each material storage frame 1811 to a suitable position, thereby ensuring the convenience of subsequent sampling work.And by using the lever 1806 on the turntable 1804 and the second limit plate 1808 on the connecting shaft 1807, the rotating plate 1810 can be driven to rotate intermittently, and each rotation is 90 degrees, which can drive the four storage frames 1811 to automatically and stably switch positions, so that the four storage frames 1811 can be automatically and intermittently moved to the cleaning, drying, loading and testing positions, ensuring the convenience and efficiency of the subsequent automated sampling and ionization work. ;

[0057] In this embodiment, the automatic processing component 19 includes a second servo motor 1901, which is welded and fixed on the top surface of the fixed plate 3. A first driving gear 1902 is welded and fixed on the output shaft of the second servo motor 1901. One side of the first driving gear 1902 is meshed and connected with a second driving gear 1903, and the other side of the first driving gear 1902 is meshed and connected with a third driving gear 1914. A first transfer frame 1904 is welded and fixed on the second driving gear 1903. The first transfer frame 1904 is rotatably connected to a first connecting pipe 1906 through a sealed bearing. The connecting pipe 1906 is provided with a first through hole 1907 and a second through hole 1908. A first driven gear 1909 is welded and fixed to the top of the first connecting pipe 1906. A first internal gear 1910 is meshed and connected to the first driven gear 1909. The top of the first internal gear 1910 is welded and fixed to the bottom end surface of the fixing plate 3. A flexible brush 1911 is fixedly connected to the first connecting pipe 1906. A small water pump 1912 is fixedly installed on the bottom end surface of the fixing plate 3. A water inlet pipe 1913 is flange-connected to the small water pump 1912. One end of the water inlet pipe 1913 is fixedly connected to the device housing 1 The bottom end of the water inlet pipe 1913 is rotatably connected to the top center of the first transfer frame 1904 through a sealed bearing. The shape and size of the second driving gear 1903 are the same as those of the third driving gear 1914. The first connecting pipe 1906 is equiangularly distributed on the first transfer frame 1904. The first through holes 1907 are symmetrically distributed on both sides of the top of the first connecting pipe 1906. Four groups of second through holes 1908 are provided. The four groups of second through holes 1908 are equiangularly distributed on the first connecting pipe 1906. Each group of second through holes 1908 is equidistantly distributed on the first connecting pipe 1906. The tubes 1906 correspond one to one with the first driven gears 1909, the second through holes 1908 and the flexible brushes 1911 are distributed alternately, and by utilizing the intermittent motion of the four storage frames 1811, the four storage frames 1811 can be moved one by one to the bottom of the first transfer frame 1904 and the bottom of the second transfer frame 1915, and by utilizing the meshing drive of the first driving gear 1902, in cooperation with the first driven gear 1909 and the first internal gear 1910, each of the first connecting tubes 1906 can be driven to automatically rotate during the revolution, thereby enabling the used storage frames 1811 to be automatically and efficiently cleaned in all directions.

[0058] In this embodiment, a second transfer frame 1915 is welded and fixed on the third driving gear 1914, a rubber plate 1905 is fixedly connected to the bottom end surface of the first transfer frame 1904 and the bottom end surface of the second transfer frame 1915, the second transfer frame 1915 is rotatably connected to a second connecting pipe 1916 through a sealed bearing, the shape and size of the first transfer frame 1904 are the same as those of the second transfer frame 1915, the diameter of the first transfer frame 1904 is larger than the diameter of the storage frame 1811, a third through hole 1917 and a fourth through hole 1918 are penetrated through the second connecting pipe 1916, a second driven gear 1919 is welded and fixed to the top end of the second connecting pipe 1916, a second internal gear 1920 is meshed and connected to the second driven gear 1919, and the top end of the second internal gear 1920 Welded and fixed on the bottom end surface of the fixed plate 3, the shape and size of the first connecting tube 1906 are the same as those of the second connecting tube 1916, and the second connecting tubes 1916 are distributed at equal angles on the second transfer frame 1915. The second connecting tubes 1916 correspond one to one to the second driven gear 1919, and the bottom end of the fourth air intake pipe 23 is rotatably connected to the top of the second transfer frame 1915 through a sealed bearing. By utilizing the revolution and rotation of each second connecting tube 1916, the cleaned storage frame 1811 can be automatically and efficiently dried in all directions, thereby ensuring the convenience and efficiency of subsequent repeated use of the storage frame 1811, effectively improving the working efficiency of the sampling device, and at the same time avoiding the dust, impurities or moisture attached to the storage frame 1811 affecting the accuracy of subsequent sampling and detection results.

[0059] In this embodiment, the shape and size of the second processing box 22 are the same as those of the first processing box 5. A positioning rod 24 is welded and fixed to the side end surface of the first processing box 5 and the side end surface of the second processing box 22. A reset spring 25 is welded and fixed inside the positioning rod 24. A stopper 26 is welded and fixed to the other end of the reset spring 25. The stopper 26 is slidably connected to the positioning rod 24. A positioning groove 28 is opened through the third magnetic plate 27. The positioning rod 24 is slidably connected to the positioning groove 28. The third magnetic plate 27 is provided with a card slot 29 on both sides of the upper and lower sides. The reset spring 25 is fixed to the positioning rod 24. The stopper 26 is distributed on both sides of the positioning rod 24, the return spring 25 corresponds to the stopper 26 one by one, the end cross-section of the stopper 26 is a right-angled trapezoid, and the length of the positioning rod 24 is greater than the thickness of the third magnetic plate 27. By utilizing the cooperation of the positioning rod 24 and the stopper 26, combined with the third magnetic plate 27 and the magnetic block 30, the filter plate 31 and the dehumidification screen plate 33 can be easily disassembled and installed, thereby ensuring the convenience and efficiency of the subsequent cleaning and replacement of the filter plate 31 and the dehumidification screen plate 33, thereby ensuring the stability of the filter plate 31 and the dehumidification screen plate 33 in subsequent long-term working conditions.

[0060] In the present embodiment, the side ends of the filter plate 31 and the side ends of the moisture removal screen plate 33 are fixedly connected with magnetic blocks 30, the magnetic blocks 30 are snap-fitted and connected in the card slots 29, the magnetic blocks 30 are magnetically adsorbed and connected with the third magnetic plate 27, the filter plate 31 is provided with a collecting groove 32, the collecting grooves 32 are distributed at equal angles on the filter plate 31, the inner wall of the first processing box 5 and the inner wall of the second processing box 22 are equidistantly installed with electric heating tubes 34, the inner wall of the first air inlet pipe 4 and the inner wall of the third air inlet pipe 21 are both connected with connecting rings 35 by bearings, the inner wall of the connecting ring 35 is welded and fixed with guide blades 36, the guide blades 36 are welded and fixed with a rotating shaft 37, and the bottom end of the rotating shaft 37 is fixed A rubber scraper 38 is fixedly connected, and the bottom end surface of the rubber scraper 38 fits with the top end surface of the filter plate 31. A feed pipe 39 is welded and fixed on the fixed plate 3, and a solenoid valve 40 is installed on the feed pipe 39. A fourth magnetic plate 41 is magnetically adsorbed and connected to the top end surface of the feed pipe 39. During the transportation of gas inside the first processing box 5 and the second processing box 22, the guide fan blades 36 can drive the rubber scraper 38 on the rotating shaft 37 to rotate automatically, so that the dust and impurities filtered on the filter plate 31 can be moved to the collection tank 32 for automatic collection, so as to avoid blockage of the filter plate 31 during long-term operation, which affects the stability of subsequent gas transportation.

[0061] It should be noted that the present invention is a sampling device for direct ionization of sampling and a method of using the same. First, when ionizing and sampling a liquid sample, the staff can open the protective door 2 on the device housing 1 and lift up the fourth magnetic plate 41 at the top of the feed tube 39. Then the staff can transport the liquid sample to be ionized into the feed tube 39. After the transport is completed, the fourth magnetic plate 41 can be covered on the top of the feed tube 39 and magnetically fixed. When starting the sampling work, the staff can drive the first servo motor 1803 and the second servo motor 1901. Under the driving action of the first servo motor 1803, the turntable 1804 and the first limit plate 1805 on the output shaft can be driven to rotate simultaneously. Under the rotation of the turntable 1804, the lever 1806 can be driven to perform a circular motion. During the movement of the lever 1806, The lever 1806 moves into the limiting groove 1809 on the second limiting plate 1808, and the second limiting plate 1808 on the connecting shaft 1807 is moved to rotate automatically. Under the continuous movement of the lever 1806, the limiting grooves 1809 on the second limiting plate 1808 can be moved to drive the second limiting plate 1808 to rotate automatically and intermittently, and each time it rotates 90°. When the second limiting plate 1808 stops rotating, it can fit with the first limiting plate 1805. Under the fitting and limiting action of the first limiting plate 1805, the second limiting plate 1808 can be prevented from shaking, thereby ensuring the stability of the intermittent rotation of the second limiting plate 1808. When the second limiting plate 1808 needs to rotate, the depression on the first limiting plate 1805 can be aligned with the second limiting plate 1808, thereby preventing the first limiting plate 1805 from blocking the rotation of the second limiting plate 1808.

[0062] Under the 90° intermittent rotation of the second limit plate 1808, the rotating plate 1810 can be driven to rotate synchronously on the supporting plate 1802 through the connecting shaft 1807. Under the 90° intermittent rotation of the rotating plate 1810, the four storage frames 1811 can be driven to automatically and stably switch positions. At this time, the first storage frame 1811 moves to the bottom of the first transfer frame 1904. At this time, under the driving action of each first hydraulic rod 1801, each storage frame on the turntable 1804 can be pushed through the supporting plate 1802. The frame 1811 moves upward until the rubber plate 1905 on the first transfer frame 1904 seals and covers the storage frame 1811 below. At this time, under the driving action of the second servo motor 1901, the second driving gear 1903 and the third driving gear 1914 that are meshed and connected can be driven to rotate simultaneously through the first driving gear 1902. At this time, under the rotation action of the second driving gear 1903, the first transfer frame 1904 can be driven to rotate synchronously. During the rotation of the first transfer frame 1904, each of the first connecting tubes 1906 can be driven to perform circular motion, that is, revolution. At this time, during the revolution of each of the first connecting tubes 1906, the top first driven gear 1909 can be driven to revolve in the first internal gear 1910. Under the meshing action of the first internal gear 1910, each of the first driven gears 1909 can be driven to automatically rotate during the revolution, and then the corresponding first connecting tubes 1906 can be driven to automatically rotate during the revolution. At this time, during the movement of each of the first connecting tubes 1906, The clean water can be delivered to the first transfer frame 1904 through the water inlet pipe 1913 on the small water pump 1912. At this time, the water in the first transfer frame 1904 can be delivered to each first connecting pipe 1906 through the first through hole 1907, and then the water can be sprayed in the storage frame 1811 through each second through hole 1908. At the same time, under the continuous rotation of the first connecting pipe 1906, in conjunction with each flexible brush 1911, the storage frame 1811 can be automatically and efficiently cleaned in all directions;

[0063] During the cleaning process, the second hydraulic rod 1816 can drive the second magnetic plate 1817 to move downward to the lowest end of the first discharge barrel 1815. At the same time, under the action of magnetic adsorption, the second magnetic plate 1817 can drive the first magnetic plate 1813 in the storage frame 1811 to move downward synchronously. At this time, the cleaned waste water can be automatically transported to the first discharge barrel 1815 through the through groove 1812 under the storage frame 1811, and then automatically drained through the rubber tube 1818 and the guide pipe 1819. After the cleaning work is completed, the second hydraulic rod 1816 can be driven, and then the first magnetic plate 1813 can be pushed to move and reset through the second magnetic plate 1817; then the first hydraulic rod 1801 can be driven to push the turntable 1804 through the support plate 1802 Each material storage frame 1811 on the upper part moves downward to reset, and then the cleaned material storage frame 1811 can move to the bottom of the second transfer frame 1915 under the 90° rotation of the turntable 1804, and then the operation can be repeated, and each first hydraulic rod 1801 is used to drive each material storage frame 1811 to move upward through the support plate 1802 and the turntable 1804, and the rubber plate 1905 on the second transfer frame 1915 is used to seal and cover the material storage frame 1811 below; similarly, the meshing drive of the first driving gear 1902 can drive the second transfer frame 1915 to rotate synchronously through the third driving gear 1914, and combined with the meshing of the second driven gear 1919 and the second internal gear 1920, each second connecting pipe 1916 can be driven to automatically rotate during the revolution;

[0064] At the same time, driven by the small air pump 20, air can be sucked through the third air inlet pipe 21 and delivered to the second processing box 22. At this time, under the action of the filter plate 31 and the dehumidification screen plate 33 inside the second processing box 22, the gas can be filtered and dehumidified, and the drying effect of the air can be improved in cooperation with each electric heating tube 34. Then, the heated and dried air can be stably delivered to the second transfer frame 1915 through the fourth air inlet pipe 23. Similarly, the heated and dried air can be stably delivered to each second connecting tube 1916 through the third through hole 1917. Then, under the jet action of each fourth through hole 1918, in cooperation with the revolution and rotation of each second connecting tube 1916, the cleaned storage frame 1811 can be cleaned. The drying process is automatic and efficient in all directions; similarly, during the drying process, the second hydraulic rod 1816 can drive the second magnetic plate 1817 to move downward to the lowest end of the second discharge barrel 1820. At the same time, under the action of magnetic adsorption, the second magnetic plate 1817 can drive the first magnetic plate 1813 in the storage frame 1811 to move downward synchronously. At this time, the excess air can be automatically transported to the second discharge barrel 1820 through the through slot 1812 under the storage frame 1811, and then the rubber tube 1818 and the guide pipe 1819 are used for automatic exhaust. After the drying work is completed, the second hydraulic rod 1816 can be driven, and the first magnetic plate 1813 can be pushed to move and reset through the second magnetic plate 1817.

[0065] After the drying work is completed, the first hydraulic rod 1801 can be driven to push the various storage frames 1811 on the turntable 1804 to move downward and reset through the supporting plate 1802. Subsequently, the dried storage frames 1811 can move to the positive direction of the feeding pipe 39 under the 90° rotation of the turntable 1804, and the automatic loading work can be carried out by opening the solenoid valve 40 on the feeding pipe 39. After the loading work is completed, the 90° rotation of the turntable 1804 can be used again to drive the loaded storage frames 1811 to automatically move to the bottom of the capillary 11. At this time, the first hydraulic rod 1801 is driven again to push the storage frames 1811 containing the liquid sample upward through the supporting plate 1802, and the sampling port at the bottom end of the capillary 11 is brought into contact with the liquid sample. At this time, sheath gas is transported to the first processing box 5 through the first air inlet pipe 4. At this time, the filter plate inside the first processing box 5 31 and the dehumidification mesh plate 33, the sheath gas can be filtered and dehumidified, and the temperature of the sheath gas can be adjusted according to actual needs in conjunction with each electric heating tube 34. Then the sheath gas can be stably transported to the fixed tube 7 through the second air inlet pipe 6, and discharged through the air guide tube 8 at the end of the fixed tube 7. At this time, when the sheath gas is ejected at a high speed at the outlet of the air guide tube 8, a micro-vacuum environment can be formed at the top outlet of the capillary 11, providing an air pressure gradient for extracting liquid samples, which is used to assist in extracting samples from the bottom sampling port of the capillary 11; then the sucked liquid sample can be transported through the capillary 11, and during the sample transportation process, a high voltage is formed by each annular electrode 12 on the capillary 11 to ionize the sample, and electrospray ionization occurs under the action of the high voltage to generate sample ions, which are transported to the mass spectrometer through the mass spectrometer inlet end 10 on the sleeve 9 for detection and analysis;

[0066] After the detection work is completed, the first hydraulic rod 1801 is used to drive the storage frame 1811 to move downward to reset. Then, the storage frame 1811 after use can move to the bottom of the first transfer frame 1904 under the 90° rotation of the turntable 1804, and carry out subsequent cleaning treatment, and so on. By using the movement of the four storage frames 1811 one by one, multiple sampling, ionization and detection work of the same liquid sample can be automatically and efficiently completed to avoid detection errors; when the sample is solid, the staff can manually load the material, and the staff can rotate the threaded rod 16 on the sealing ring 17. Under the action of the threaded rotation of the threaded rod 16, the sealing ring 17 can be driven to move upward to the top of the second liquid guide tube 14 to ensure the stability of the subsequent solvent transportation work. Then, the liquid-solid extraction liquid can be transported to the first liquid guide tube 13 through the second liquid guide tube 14, and the solvent is sprayed on the solid surface through the third liquid guide tube 15 for liquid-solid extraction, and then extraction and ionization are performed through the same operation, and subsequent detection and analysis are performed;

[0067] During the operation of the sampling device, when the sheath gas is being transported, the guide blades 36 can be driven to automatically rotate in the first air inlet pipe 4 through the connecting ring 35, and then the rubber scraper 38 can be driven to automatically rotate through the rotating shaft 37. At this time, under the rotation of the rubber scraper 38, the dust and impurities filtered on the filter plate 31 can be moved to the inside of the collection tank 32 for automatic collection, thereby avoiding clogging of the filter plate 31 during long-term operation, which affects the stability of subsequent gas transportation. Similarly, during the drying gas transportation process, the guide blades 36 in the third air inlet pipe 21 also rotate automatically, and the rubber scraper 38 can also be used to move the dust and impurities filtered on the filter plate 31 inside the second processing box 22 to the inside of the collection tank 32 for automatic collection.

[0068] After the sampling device is finished working, the staff can push the stopper 26 to move into the positioning rod 24. At this time, the third magnetic plate 27 loses its blocking force, and the magnetic block 30 is connected to the second processing box 22 and the first processing box 5 through sliding. Therefore, the third magnetic plate 27 can use magnetism to pull the filter plate 31 and the moisture-removing screen plate 33 on the two magnetic blocks 30 to automatically move outward, thereby conveniently completing the removal of the filter plate 31 and the moisture-removing screen plate 33, thereby ensuring the convenience and efficiency of subsequent cleaning and replacement of the filter plate 31 and the moisture-removing screen plate 33. Similarly, when the filter plate 31 and the moisture-removing screen plate 33 need to be snap-fitted and installed, it is only necessary to insert the magnetic blocks 30 on the filter plate 31 and the moisture-removing screen plate 33 into the slots 29 on the upper and lower sides of the third magnetic plate 27, and then The filter plate 31 and the dehumidification screen plate 33 can be stably inserted into the second processing box 22 or the first processing box 5, and during the insertion process of the filter plate 31 and the dehumidification screen plate 33, the positioning groove 28 on the third magnetic plate 27 can be stably inserted on the positioning rod 24. At this time, the third magnetic plate 27 can use the positioning groove 28 to push the inclined surface of the block 26. At this time, under the guiding action of the inclined surface of the block 26, the third magnetic plate 27 can use the positioning groove 28 to push the block 26 to automatically move into the positioning rod 24 until the third magnetic plate 27 passes over the block 26. At this time, the block 26 can automatically move outward and reset under the elastic action of the reset spring 25, and then the third magnetic plate 27 can be automatically limited to ensure the stability of the subsequent engagement work of the third magnetic plate 27, the filter plate 31 and the dehumidification screen plate 33.

[0069] Although the present invention has been described above with reference to the embodiments, various modifications may be made thereto and parts thereof may be replaced by equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the various features in the embodiments disclosed in the present invention may be used in combination with each other in any manner, and the fact that these combinations are not exhaustively described in this specification is only for the sake of omitting space and saving resources. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A sampling device for direct ionization of samples, comprising a device housing (1), a small air pump (20), a third magnetic plate (27), a filter plate (31) and a moisture removal screen plate (33), characterized in that: A protective door (2) is installed on the device housing (1); a fixing plate (3) is welded and fixed inside the device housing (1); a first air inlet pipe (4) is welded and fixed on the top of the device housing (1); the bottom end of the first air inlet pipe (4) is connected to a first processing box (5); the bottom end of the first processing box (5) is connected to a second air inlet pipe (6); the bottom end of the second air inlet pipe (6) is connected to a fixing pipe (7); one end of the fixing pipe (7) is connected to an air guide pipe (8); the end of the air guide pipe (8) is fixedly connected to a sleeve (9); the end of the sleeve (9) is bolted to an inlet end (10) of a mass spectrometer; a capillary tube (11) is fixedly connected inside the fixing pipe (7); an annular electrode (12) is fixedly installed inside the fixing pipe (7); the annular electrode (12) is sleeved on the capillary tube (11); a first liquid guide tube (13) is fixedly connected to the fixing pipe (7); the first liquid guide tube (13) is fixedly connected to the fixing pipe (7); The side end of the tube (13) is connected to a second liquid guide tube (14), the second liquid guide tube (14) is fixedly connected to the side end of the device housing (1), the bottom end of the first liquid guide tube (13) is connected to a third liquid guide tube (15), the top of the first liquid guide tube (13) is threadedly connected to a threaded rod (16), the bottom end of the threaded rod (16) is rotatably connected to a sealing ring (17), a multifunctional workbench (18) is installed at the bottom of the device housing (1), an automatic processing component (19) is installed on the fixed plate (3), a third air intake pipe (21) is flange-connected to the small air pump (20), one end of the third air intake pipe (21) is fixedly connected to the side end of the device housing (1), the bottom end of the third air intake pipe (21) is connected to a second processing box (22), the bottom end of the second processing box (22) is connected to a fourth air intake pipe (23), and the fourth air intake pipe (23) is fixedly connected to the fixed plate (3).

2. A sampling device for direct ionization of samples according to claim 1, characterized in that: The inner diameters of the air guide tube (8) and the third liquid guide tube (15) are both larger than the diameter of the fixed tube (7); the fixed tube (7) is arranged in the middle of the fixed tube (7); the annular electrodes (12) are equidistantly distributed in the fixed tube (7); the threaded rods (16) are symmetrically distributed on both sides of the sealing ring (17); the sealing ring (17) is slidably connected in the first liquid guide tube (13); the sealing ring (17) is sleeved on the capillary tube (11); the outer wall of the sealing ring (17) is in contact with the inner wall of the first liquid guide tube (13); and the inner wall of the sealing ring (17) is in contact with the outer wall of the capillary tube (11).

3. A sampling device for direct ionization of samples according to claim 1, characterized in that: The multifunctional workbench (18) comprises a first hydraulic rod (1801), the bottom end of the first hydraulic rod (1801) is fixedly mounted on the inner bottom end surface of the device housing (1), the top end of the first hydraulic rod (1801) is fixedly connected to a support plate (1802), the bottom end surface of the support plate (1802) is fixedly mounted with a first servo motor (1803), a turntable (1804) and a first limit plate (1805) are welded and fixedly mounted on the output shaft of the first servo motor (1803), a shifting rod (1806) is welded and fixedly mounted on the turntable (1804), a connecting shaft (1807) is rotatably connected to the support plate (1802), a second limit plate (1808) is welded and fixedly mounted on the bottom end of the connecting shaft (1807), and the A limiting groove (1809) is provided on the second limiting plate (1808); a rotating plate (1810) is welded and fixed to the top end of the connecting shaft (1807); four first hydraulic rods (1801) are provided, and the four first hydraulic rods (1801) are evenly distributed around the bottom of the supporting plate (1802); the side end surface of the first limiting plate (1805) is in contact with the side end surface of the second limiting plate (1808); four limiting grooves (1809) are provided, and the four limiting grooves (1809) are respectively provided on the second limiting plate (1808) at equal angles; the bottom end surface of the rotating plate (1810) is in contact with the top end surface of the supporting plate (1802); and the top end of the connecting shaft (1807) is fixed to the middle part of the bottom of the rotating plate (1810).

4. A sampling device for direct ionization of samples according to claim 3, characterized in that: A material storage frame (1811) is bolted to the top surface of the rotating plate (1810), a through groove (1812) is formed through the rotating plate (1810), a first magnetic plate (1813) is slidably connected in the through groove (1812), a first material discharge barrel (1815) and a second material discharge barrel (1820) are welded and fixed to the support plate (1802), a second hydraulic rod (1816) is fixedly installed at the bottom of the first material discharge barrel (1815) and the bottom of the second material discharge barrel (1820), a second magnetic plate (1817) is fixedly connected to the top of the second hydraulic rod (1816), a sealing ring (1814) is fixedly connected to the first magnetic plate (1813) and the second magnetic plate (1817), a bottom side end of the first material discharge barrel (1815) and a bottom side end of the second material discharge barrel (1820) are fixedly connected A rubber tube (1818), the other end of which is fixedly connected to a material guide tube (1819), and the material guide tube (1819) is welded and fixed to the bottom side end of the device housing (1). Four material storage frames (1811) are provided, and the four material storage frames (1811) are distributed at equal angles on the rotating plate (1810). The material storage frames (1811) correspond to the through grooves (1812) one by one, and the diameter of the through grooves (1812), the inner diameter of the material storage frames (1811) and the inner diameter of the first material discharge barrel (1815) are equal. The inner wall of the material storage frame (1811) fits with the outer wall of the sealing ring (1814), the shape and size of the first material discharge barrel (1815) are the same as the shape and size of the second material discharge barrel (1820), and the shape and size of the first magnetic plate (1813) are the same as the shape and size of the second magnetic plate (1817).

5. A sampling device for direct ionization of samples according to claim 4, characterized in that: The automatic processing component (19) comprises a second servo motor (1901), the second servo motor (1901) is welded and fixed on the top surface of the fixing plate (3), a first driving gear (1902) is welded and fixed on the output shaft of the second servo motor (1901), one side of the first driving gear (1902) is meshedly connected with a second driving gear (1903), the other side of the first driving gear (1902) is meshedly connected with a third driving gear (1914), a first transfer frame (1904) is welded and fixed on the second driving gear (1903), the first transfer frame (1904) is rotatably connected with a first connecting pipe (1906) via a sealed bearing, and the first connecting pipe (1906) is penetrated by a first through hole (1907) and a second through hole (1914). The first connecting tube (1906) has a hole (1908), a first driven gear (1909) is welded and fixed to the top end of the first connecting tube (1906), a first internal gear (1910) is meshed and connected to the first driven gear (1909), the top end of the first internal gear (1910) is welded and fixed to the bottom end surface of the fixing plate (3), a flexible brush (1911) is fixedly connected to the first connecting tube (1906), a small water pump (1912) is installed and fixed to the bottom end surface of the fixing plate (3), a water inlet pipe (1913) is flange-connected to the small water pump (1912), one end of the water inlet pipe (1913) is fixedly connected to the side end of the device housing (1), and the bottom end of the water inlet pipe (1913) is rotatably connected to the top center of the first transfer frame (1904) through a sealed bearing.

6. A sampling device for direct ionization of samples according to claim 5, characterized in that: The shape and size of the second driving gear (1903) are the same as those of the third driving gear (1914); the first connecting tube (1906) is distributed at equal angles on the first transfer frame (1904); the first through holes (1907) are symmetrically distributed on both sides of the top of the first connecting tube (1906); four groups of second through holes (1908) are provided; the four groups of second through holes (1908) are distributed at equal angles on the first connecting tube (1906); each group of second through holes (1908) is equidistantly distributed on the first connecting tube (1906); the first connecting tube (1906) corresponds to the first driven gear (1909) one by one; and the second through holes (1908) and the flexible brushes (1911) are distributed alternately.

7. The sampling device for direct ionization of samples according to claim 5, characterized in that: A second transfer frame (1915) is welded and fixed on the third driving gear (1914); a rubber plate (1905) is fixedly connected to the bottom end surface of the first transfer frame (1904) and the bottom end surface of the second transfer frame (1915); the second transfer frame (1915) is rotatably connected to a second connecting pipe (1916) via a sealing bearing; the shape and size of the first transfer frame (1904) are the same as those of the second transfer frame (1915); the diameter of the first transfer frame (1904) is larger than the diameter of the material storage frame (1811); a third through hole (1917) and a fourth through hole (1918) are penetrated through the second connecting pipe (1916); A second driven gear (1919) is welded and fixed to the top end of the tube (1916); a second internal gear (1920) is meshedly connected to the second driven gear (1919); the top end of the second internal gear (1920) is welded and fixed to the bottom end surface of the fixed plate (3); the shape and size of the first connecting tube (1906) are the same as those of the second connecting tube (1916); the second connecting tubes (1916) are distributed at equal angles on the second transfer frame (1915); the second connecting tubes (1916) correspond one to one to the second driven gear (1919); and the bottom end of the fourth intake pipe (23) is rotatably connected to the top of the second transfer frame (1915) via a sealed bearing.

8. The sampling device for direct ionization of samples according to claim 1, characterized in that: The shape and size of the second processing box (22) are the same as those of the first processing box (5). A positioning rod (24) is welded and fixed on the side end surface of the first processing box (5) and the side end surface of the second processing box (22). A return spring (25) is welded and fixed inside the positioning rod (24). A stopper (26) is welded and fixed at the other end of the return spring (25). The stopper (26) is slidably connected in the positioning rod (24). A positioning groove (28) is provided through the third magnetic plate (27). The positioning rod (24) is slidably connected in the positioning groove (28). The third magnetic plate (27) has slots (29) on the upper and lower sides. The return spring (25) is symmetrically distributed on both sides of the positioning rod (24). The return spring (25) corresponds to the stopper (26) one by one. The end cross section of the stopper (26) is a right-angle trapezoid. The length of the positioning rod (24) is greater than the thickness of the third magnetic plate (27).

9. A sampling device for direct ionization of samples according to claim 8, characterized in that: The side ends of the filter plate (31) and the side ends of the moisture removal screen plate (33) are both fixedly connected with magnetic blocks (30), the magnetic blocks (30) are snap-fitted and connected in the slots (29), the magnetic blocks (30) are magnetically adsorbed and connected to the third magnetic plate (27), the filter plate (31) is provided with collecting grooves (32), the collecting grooves (32) are distributed at equal angles on the filter plate (31), the inner wall of the first processing box (5) and the inner wall of the second processing box (22) are both equidistantly installed with electric heating pipes (34), the inner wall of the first air inlet pipe (4) and the inner wall of the third air inlet pipe (21) are The bearing is connected to a connecting ring (35), a guide blade (36) is welded and fixed on the inner wall of the connecting ring (35), a rotating shaft (37) is welded and fixed on the guide blade (36), a rubber scraper (38) is fixedly connected to the bottom end of the rotating shaft (37), the bottom end surface of the rubber scraper (38) is in contact with the top end surface of the filter plate (31), a feed pipe (39) is welded and fixed on the fixed plate (3), a solenoid valve (40) is installed on the feed pipe (39), and a fourth magnetic plate (41) is magnetically adsorbed and connected to the top end surface of the feed pipe (39).

10. A method for using a sampling device for direct ionization of samples, using the sampling device for direct ionization of samples as claimed in claim 1, characterized in that: The following steps are involved: S1: When ionization sampling is performed on a liquid sample, the liquid sample to be tested is transported to the multifunctional workbench (18) through the feed pipe (39); when ionization sampling is performed on a solid sample, the staff transports the sample to the multifunctional workbench (18) by opening the protective door (2) on the device housing (1); S2: using the cooperation of the multifunctional workbench (18) and the automatic processing component (19) to automatically complete the cleaning, drying, testing and subsequent unloading of the vessel; S3: After the sample to be tested is transported to the multifunctional workbench (18), ensure that the sample is in contact with the bottom sampling port of the capillary tube (11); S4: delivering sheath gas into the fixed tube (7). When the sheath gas is ejected at high speed at the outlet of the air guide tube (8), a micro-vacuum environment can be formed at the top outlet of the capillary tube (11), providing a gas pressure gradient for extracting liquid samples, and assisting the extraction of samples from the sampling port at the bottom end of the capillary tube (11); S5: using each annular electrode (12) on the capillary (11) to form a high voltage to ionize the sample, electrospray ionization occurs under the action of the high voltage, and sample ions are generated, which are transported to the mass spectrometer through the mass spectrometer inlet end (10) on the sleeve (9) for detection and analysis; S6: When the sample is solid, a solvent is sprayed on the solid surface through the first liquid conduit (13) and the third liquid conduit (15) to perform liquid-solid extraction, and then extraction and ionization are performed through the same operation, and subsequent detection and analysis are performed.

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