Dehydration reaction device for producing benzyloxycarbonyl succinimide

Abstract

The utility model relates to the technical field of a dehydration reaction device for producing benzyloxycarbonyl succinimide, and discloses a dehydration reaction device for producing benzyloxycarbonyl succinimide, the top of a base is provided with a dehydration reaction mechanism, and the right side of the dehydration reaction mechanism is provided with a feeding mechanism. A connecting gear drives an external rotating gear and a gear II to rotate, so that a gear I rotates in the gear II, a stirring rod and a water filtering net barrel are driven to oppositely rotate in a reaction barrel, p-benzyloxycarbonyl succinimide and a medicament are fully mixed, the dehydration reaction effect of the benzyloxycarbonyl succinimide is improved, and the dehydration effect of the p-benzyloxycarbonyl succinimide is improved. A screw rod drives a scraping plate to slide outside a limiting rod, so that residual benzyloxycarbonyl succinimide on the inner wall of a water filtering net barrel can be scraped off, cleaning is facilitated, benzyloxycarbonyl succinimide in a feeding bin is driven by the feeding bin to enter a dehydration reaction mechanism for dehydration, and the dehydration efficiency is improved. Benzoxycarbonyl succinimide can be conveyed into the reaction barrel easily.

Description

Technical Field

[0001] The utility model relates to the technical field of a dehydration reaction device for producing benzyloxycarbonyl succinimide, in particular to a dehydration reaction device for producing benzyloxycarbonyl succinimide. Background Art

[0002] Benzyloxycarbonyl succinimide is a white to off-white solid and a peptide precursor reagent used to prepare peptide thioacids. It is also used to prepare aminoglycoside derivatives, has the function of topoisomerase, has inhibitory effects on humans and bacteria, and is used as a peptide reagent, amino acid, and aminoglycoside antibiotic synthesis to selectively introduce Z-amino protection reagents. In the process of producing Benzyloxycarbonyl succinimide, Benzyloxycarbonyl succinimide needs to be dehydrated, so a dehydration reaction device for the production of Benzyloxycarbonyl succinimide is needed.

[0003] In the prior art, when performing a dehydration reaction on benzyloxycarbonyl succinimide, the benzyloxycarbonyl succinimide is directly mixed with a reagent and allowed to stand to react and thereby dehydrate. If a dehydration reaction device for producing benzyloxycarbonyl succinimide and the reaction reagent are not sufficiently mixed, the dehydration effect may be poor, and the reactants may stick to the inner wall of the device, which is also very troublesome to clean. Utility Model Content

[0004] The utility model aims to provide a dehydration reaction device for producing benzyloxycarbonyl succinimide to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above object, the utility model provides the following technical solution: a dehydration reaction device for producing benzyloxycarbonyl succinimide, comprising a base, a dehydration reaction mechanism is arranged on the top of the base, and a feeding mechanism is arranged on the right side of the dehydration reaction mechanism;

[0006] The dehydration reaction mechanism comprises a mixing component and a dehydration filtering component, wherein the mixing component is arranged on the top of the dehydration filtering component;

[0007] The mixing assembly includes a placement stand, which is fixedly connected to the top of the base, a drive box is fixedly connected to the right side of the placement stand, a motor 1 is fixedly connected to the top of the drive box, a connecting gear is fixedly connected to the output end of the motor 1, a gear 2 is meshed on the outside of the connecting gear, a gear 1 is rotatably connected to the top of the gear 2, a rotating gear is meshed on the outside of the gear 1, a triangular bracket is arranged on the outside of the rotating gear, and since the motor 1 is arranged, it is beneficial to provide power for the connecting gear to drive the external rotating gear and the gear 1 to rotate.

[0008] Preferably, through holes are provided at corresponding positions of the triangular bracket and the rotating gear, connecting gear and gear one, and gear one is rotatably connected to the inside of the triangular bracket. Since gear one is provided, it is beneficial to drive the water filter net barrel at the bottom of gear one to rotate inside the reaction barrel.

[0009] Preferably, the dehydration and filtration assembly includes a stirring rod, which is fixedly connected to the bottom of gear two, the bottom of the drive box is fixedly connected to a reaction barrel, the bottom of gear one is fixedly connected to a rotating rod, the bottom of the rotating rod is fixedly connected to a water filter net barrel, the inner bottom end of the drive box is fixedly connected to motor two, the output end of motor two is fixedly connected to a screw, the bottom of the drive box is fixedly connected to a limiting rod, and the external thread of the screw is connected to a scraper. Since the scraper is provided, it is beneficial to scrape off the residual benzoyloxycarbonyl succinimide on the inner wall of the water filter net barrel.

[0010] Preferably, a rotating groove is provided at the corresponding positions of the reaction barrel and the water filter net barrel, and the water filter net barrel is rotatably connected to the inside of the reaction barrel. The provision of the water filter net barrel is conducive to the discharge of water released by benzyloxycarbonyl succinimide.

[0011] Preferably, the feeding mechanism includes a feeding pipe, which is fixedly connected to the right side of the placement stand, and the bottom of the feeding pipe is fixedly connected to a motor three, the output end of the motor three is fixedly connected to a feeding spiral blade, and the outside of the motor three is fixedly connected to a feed bin. Due to the feeding spiral blade, it is beneficial to bring benzoyloxycarbonyl succinimide into the water filter net barrel.

[0012] Preferably, through holes are provided at corresponding positions of the stirring rod and the rotating rod, and the rotating rod is rotatably connected to the inside of the stirring rod. The provision of the stirring rod is conducive to fully mixing the benzyloxycarbonyl succinimide and the reaction reagent.

[0013] Compared with the prior art, the utility model provides a dehydration reaction device for producing benzyloxycarbonyl succinimide, which has the following beneficial effects:

[0014] 1. The dehydration reaction device for producing benzyloxycarbonyl succinimide is provided with a mixing component and a dehydration filtering component in a dehydration reaction mechanism, wherein the mixing component is provided on the top of the dehydration filtering component, and the external rotating gear and the gear 2 are driven to rotate by a connecting gear, so that the gear 1 rotates inside the gear 2, and the stirring rod and the water filter net barrel are driven to rotate oppositely inside the reaction barrel, so that the benzyloxycarbonyl succinimide and the reagent are fully mixed, which is beneficial to improving the dehydration reaction effect of the benzyloxycarbonyl succinimide, and the scraper is driven by a screw to slide outside the limiting rod, so that the residual benzyloxycarbonyl succinimide on the inner wall of the water filter net barrel is scraped off, which is convenient for cleaning.

[0015] 2. The dehydration reaction device for producing benzyloxycarbonyl succinimide is used in conjunction with the dehydration reaction mechanism through a feeding mechanism, and the benzyloxycarbonyl succinimide in the feed bin is driven into the dehydration reaction mechanism through the feed bin for dehydration, thereby facilitating the transportation of the benzyloxycarbonyl succinimide into the reaction barrel. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative labor:

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the dehydration reaction mechanism of the utility model;

[0019] Figure 3 This is a schematic diagram of the structure of the mixing assembly of the dehydration reaction mechanism of the utility model;

[0020] Figure 4 This is a schematic diagram of the structure of the dehydration filtration component of the dehydration reaction mechanism of the utility model;

[0021] Figure 5 This is a schematic cross-sectional view of the dehydration filter assembly of the dehydration reaction mechanism of the utility model;

[0022] Figure 6 It is a schematic diagram of the structure of the feeding mechanism of the utility model.

[0023] In the figure: 1. base; 2. dehydration reaction mechanism; 21. mixing component; 211. placing stand; 212. driving box; 213. motor one; 214. rotating gear; 215. triangular bracket; 216. connecting gear; 217. gear one; 218. gear two; 22. dehydration filtration component; 221. stirring rod; 222. reaction barrel; 223. water filter net barrel; 224. motor two; 225. screw; 226. limit rod; 227. scraper; 228. rotating rod; 3. feeding mechanism; 31. feeding pipe; 32. motor three; 33. feeding spiral blade; 34. feeding bin. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0026] Embodiment 1:

[0027] See also Figure 1-6 The utility model provides a technical solution: a dehydration reaction device for producing benzyloxycarbonyl succinimide, comprising a base 1, a dehydration reaction mechanism 2 is arranged on the top of the base 1, and a feeding mechanism 3 is arranged on the right side of the dehydration reaction mechanism 2;

[0028] The dehydration reaction mechanism 2 includes a mixing component 21 and a dehydration filtering component 22, and the mixing component 21 is arranged on the top of the dehydration filtering component 22;

[0029] The mixing assembly 21 includes a placing stand 211, which is fixedly connected to the top of the base 1, and a driving box 212 is fixedly connected to the right side of the placing stand 211, and a motor 1 213 is fixedly connected to the top of the driving box 212, and a connecting gear 216 is fixedly connected to the output end of the motor 1 213, and a gear 2 218 is meshed with the outside of the connecting gear 216, and a gear 1 217 is rotatably connected to the top of the gear 218, and a rotating gear 214 is meshed with the outside of the gear 1 217, and a triangular bracket 215 is arranged outside the rotating gear 214. Since the motor 1 213 is arranged, it is conducive to providing power for the connecting gear 216 to drive the external rotating gears 214 and gear 1 217 to rotate.

[0030] Furthermore, through holes are provided at corresponding positions of the triangular bracket 215, the rotating gear 214, the connecting gear 216, and the gear 1 217. The gear 1 217 is rotatably connected to the inside of the triangular bracket 215. Since the gear 1 217 is provided, it is beneficial to drive the water filter net barrel 223 at the bottom of the gear 1 217 to rotate inside the reaction barrel 222.

[0031] Furthermore, the dehydration filtering assembly 22 includes a stirring rod 221, which is fixedly connected to the bottom of the gear 218, a reaction barrel 222 is fixedly connected to the bottom of the drive box 212, a rotating rod 228 is fixedly connected to the bottom of the gear 1 217, a water filter net barrel 223 is fixedly connected to the bottom of the rotating rod 228, a motor 224 is fixedly connected to the inner bottom end of the drive box 212, a screw 225 is fixedly connected to the output end of the motor 224, a limiting rod 226 is fixedly connected to the bottom of the drive box 212, and a scraper 227 is threadedly connected to the outer surface of the screw 225. Since the scraper 227 is provided, it is helpful to scrape off the residual benzoyloxycarbonyl succinimide on the inner wall of the water filter net barrel 223.

[0032] Furthermore, a rotating groove is provided at the corresponding position of the reaction barrel 222 and the water filter net barrel 223, and the water filter net barrel 223 is rotatably connected to the inside of the reaction barrel 222. The provision of the water filter net barrel 223 is conducive to draining the water released by the benzyloxycarbonyl succinimide.

[0033] Furthermore, through holes are provided at corresponding positions of the stirring rod 221 and the rotating rod 228, and the rotating rod 228 is rotatably connected to the inside of the stirring rod 221. The stirring rod 221 is provided to facilitate sufficient mixing of the benzyloxycarbonyl succinimide and the reaction reagent.

[0034] Embodiment 2:

[0035] See also Figure 6 In combination with Example 1, it is further obtained that the feeding mechanism 3 includes a feeding pipe 31, the feeding pipe 31 is fixedly connected to the right side of the placement stand 211, the bottom of the feeding pipe 31 is fixedly connected to a motor 32, the output end of the motor 32 is fixedly connected to a feeding spiral blade 33, and the outside of the motor 32 is fixedly connected to a feeding bin 34. Due to the feeding spiral blade 33, it is beneficial to bring the benzyloxycarbonyl succinimide into the water filter net barrel 223.

[0036] In actual operation, when the device is used, first, the benzyloxycarbonyl succinimide to be dehydrated is placed in the feed bin 34, and the driving motor 32 drives the feeding spiral blade 33 to rotate inside the feeding tube 31, so that the benzyloxycarbonyl succinimide inside the feed bin 34 is brought into the water filter barrel 223 inside the reaction barrel 222, and then the driving motor 1 213 drives the connecting gear 216 to drive the external gear 218 and the rotating gear 214 to rotate, and the rotating gear 214 drives the gear 1 217 to rotate inside the gear 2 218, so that The water filter net barrel 223 and the stirring rod 221 rotate in opposite directions, so that the benzyloxycarbonyl succinimide and the reactant are fully mixed, thereby dehydrating. The water dehydrated from the benzyloxycarbonyl succinimide is discharged into the reaction barrel 222 through the water filter net barrel 223 and then discharged. The dehydrated benzyloxycarbonyl succinimide is discharged through the valve at the bottom of the water filter net barrel 223, and then driven by the motor 224, so that the screw 225 drives the external scraper 227 to slide outside the limit rod 226, thereby scraping off the benzyloxycarbonyl succinimide remaining on the inner wall of the water filter net barrel 223.

[0037] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

Claims

1. A dehydration reaction device for producing benzyloxycarbonyl succinimide, comprising a base (1), characterized in that: A dehydration reaction mechanism (2) is arranged on the top of the base (1), and a loading mechanism (3) is arranged on the right side of the dehydration reaction mechanism (2); The dehydration reaction mechanism (2) comprises a mixing component (21) and a dehydration filtering component (22), wherein the mixing component (21) is arranged on top of the dehydration filtering component (22); The mixing assembly (21) comprises a placement stand (211), the placement stand (211) being fixedly connected to the top of the base (1), a driving box (212) being fixedly connected to the right side of the placement stand (211), a motor 1 (213) being fixedly connected to the top of the driving box (212), a connecting gear (216) being fixedly connected to the output end of the motor 1 (213), a connecting gear (216) being meshed with a gear 2 (218) on the outside of the connecting gear (216), a gear 1 (217) being rotatably connected to the top of the gear 2 (218), a rotating gear (214) being meshed with the outside of the gear 1 (217), and a triangular bracket (215) being arranged on the outside of the rotating gear (214).

2. The dehydration reaction device for producing benzyloxycarbonyl succinimide according to claim 1, characterized in that: Through holes are provided at corresponding positions of the triangular bracket (215), the rotating gear (214), the connecting gear (216), and the first gear (217), and the first gear (217) is rotatably connected to the inside of the triangular bracket (215).

3. The dehydration reaction device for producing benzyloxycarbonyl succinimide according to claim 1, characterized in that: The dewatering and filtering assembly (22) comprises a stirring rod (221), the stirring rod (221) being fixedly connected to the bottom of gear 2 (218); the bottom of the driving box (212) being fixedly connected to a reaction barrel (222); the bottom of the gear 1 (217) being fixedly connected to a rotating rod (228); the bottom of the rotating rod (228) being fixedly connected to a water filter net barrel (223); the inner bottom end of the driving box (212) being fixedly connected to motor 2 (224); the output end of the motor 2 (224) being fixedly connected to a screw rod (225); the bottom of the driving box (212) being fixedly connected to a limit rod (226); and the outer thread of the screw rod (225) being connected to a scraper (227).

4. The dehydration reaction device for producing benzyloxycarbonyl succinimide according to claim 3, characterized in that: Rotating grooves are provided at corresponding positions of the reaction barrel (222) and the water filter net barrel (223), and the water filter net barrel (223) is rotatably connected to the interior of the reaction barrel (222).

5. The dehydration reaction device for producing benzyloxycarbonyl succinimide according to claim 3, characterized in that: The feeding mechanism (3) comprises a feeding pipe (31), the feeding pipe (31) being fixedly connected to the right side of the placement stand (211), the bottom of the feeding pipe (31) being fixedly connected to a motor three (32), the output end of the motor three (32) being fixedly connected to a feeding spiral blade (33), and the outside of the motor three (32) being fixedly connected to a feeding bin (34).

6. The dehydration reaction device for producing benzyloxycarbonyl succinimide according to claim 5, characterized in that: Through holes are provided at corresponding positions of the stirring rod (221) and the rotating rod (228), and the rotating rod (228) is rotatably connected to the inside of the stirring rod (221).

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