Tension test fixing device for tissue engineering skin

Abstract

The utility model belongs to the technical field of medical instruments, and particularly discloses a tension test fixing device for tissue engineering skin, which comprises a test device, a base, an electromagnetic pressure plate and an adjusting mechanism. The testing device is placed on the planar workbench, the base is installed in the testing device, the tissue engineering skin is placed at the upper end of the base, and a first cavity for suspending and testing the tissue engineering skin is formed in the center of the base; the electromagnetic pressing plate is provided with a second cavity for testing, the electromagnetic pressing plate is connected with the base through magnetic adsorption, and the tissue engineering skin is fixed on the base by the electromagnetic pressing plate during adsorption; the adjusting mechanism adjusts the magnetic attraction force of the electromagnetic pressing plate to the base, the tissue engineering skin is clamped more effectively by adjusting the magnetic force, and the tissue engineering skin is effectively prevented from being broken or falling off at the clamped position.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical devices, and in particular relates to a tension test fixing device for tissue engineering skin. Background Art

[0002] How to promote and accelerate the healing and repair of wounds, such as large-area trauma (such as burns), acute wounds and long-term chronic wounds (such as venous ulcers, diabetic ulcers and pressure ulcers), is an important issue of clinical concern. Tissue-engineered skin provides an effective treatment approach to solve this problem.

[0003] Tissue-engineered skin is a tissue-engineered skin with complete biological structure and function that is cultured in vitro using the principles and methods of engineering and cell biology and then transplanted into the human body to repair the appearance and function of the skin. Generally, after the tissue-engineered skin is produced in the factory, it leaves the incubator and is stored and transported to the hospital for treatment of patients. In order to ensure that tissue-engineered skin is better used in clinical practice, it needs to be strictly quality-controlled and performance-tested before leaving the factory. Therefore, after the cultivation is completed, the compatibility and safety of the tissue-engineered skin need to be tested, as well as the biophysical properties, especially the biomechanical properties. Pre-stretching stress is an important one. Only when the pre-stretching stress meets the requirements can it provide stable mechanical properties when treating patients, such as arbitrary shearing and suturing. Tension is the manifestation of pre-stretching stress in the skin's resistance to pressure.

[0004] Measuring tension, because tissue-engineered skin is a low-strength membrane-like biomaterial with a thin thickness, in addition to requiring a special test instrument, conventional clamps are not suitable for placing tissue-engineered skin. The current clamping method is to place the tissue-engineered skin in a ring-shaped clamp, which can minimize the impact of the clamp on the test results. However, the thickness of tissue-engineered skin ranges from 0.5-4mm, and different thicknesses require different clamping forces. The clamping force of the current clamp cannot be adjusted. Thin tissue-engineered skin is prone to breakage at the clamping point, and thick tissue-engineered skin is prone to fall off. Utility Model Content

[0005] The utility model aims to overcome the defects of the prior art and provide a tension test fixture for tissue engineering skin to solve the problem that the tissue engineering skin is prone to breakage or falling off at the clamping position when the clamping force is constant.

[0006] The specific technical solutions are as follows:

[0007] A tension test fixture for tissue engineering skin, comprising:

[0008] Test equipment;

[0009] A base is installed in the test device, the tissue-engineered skin is placed on the upper end of the base, and a first cavity is provided in the center of the base for suspending and testing the tissue-engineered skin;

[0010] An electromagnetic pressing plate, wherein the electromagnetic pressing plate is provided with a second cavity for testing, and the electromagnetic pressing plate is connected to the base by magnetic attraction, and during the adsorption, the electromagnetic pressing plate fixes the tissue-engineered skin on the base; and

[0011] An adjusting mechanism is electrically connected to the electromagnetic pressure plate, and the adjusting mechanism adjusts the magnetic attraction force of the electromagnetic pressure plate on the base.

[0012] In one embodiment, the regulating mechanism is a sliding rheostat, and the electromagnetic pressure plate is electrically connected to a DC power supply via the sliding rheostat.

[0013] In one embodiment, the base is made of iron, and the electromagnetic pressure plate is made of soft iron.

[0014] In one of the embodiments, the base is provided with a plurality of positioning posts, the positioning posts are evenly spaced along the circumference, and the electromagnetic pressure plate is provided with positioning holes matching the positioning posts.

[0015] In one of the embodiments, each end surface of the electromagnetic pressure plate is provided with anti-slip grooves.

[0016] In one embodiment, the testing device includes: a sealed box, a pressure sensor and a displacement sensor; the base is placed in the sealed box, and the displacement sensor is installed in the sealed box; the pressure sensor is installed on the sealed box, and the sealed box is connected to an external air pressure boosting device and the air pressure can be adjusted.

[0017] In one of the embodiments, the sealed box is provided with a positioning groove for accommodating the base.

[0018] Beneficial effects of the utility model:

[0019] The above-mentioned tension test fixture for tissue engineering skin is provided with an adjustment mechanism in the test fixture. During the test, the current in the circuit is changed according to the area and thickness of the tissue engineering skin, thereby obtaining a suitable magnetic adsorption of the electromagnetic pressure plate to the base, which can clamp the tissue engineering skin more effectively and effectively prevent the tissue engineering skin from breaking or falling off at the clamping point. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the specific implementation of the utility model, the following will briefly introduce the drawings required for use in the specific implementation. In all the drawings, each element or part is not necessarily drawn according to the actual scale.

[0021] Figure 1 It is a schematic diagram of the structure of the tension test fixture of tissue engineering skin of the utility model;

[0022] Figure 2 It is a structural schematic diagram of the base and the electromagnetic pressure plate.

[0023] Reference numerals:

[0024] 1-test device, 11-sealed box, 111-opening, 12-box door, 13-base, 131-positioning slot,

[0025] 14-pressure sensor, 15-displacement sensor, 2-base, 21-first cavity, 22-positioning column,

[0026] 3-electromagnetic pressure plate, 31-second cavity, 32-positioning hole, 4-tissue engineering skin, 5-adjusting mechanism, 6-power supply, 7-computer, 8-air pressure valve. DETAILED DESCRIPTION

[0027] The following embodiments of the technical solution of the utility model are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the utility model, and are therefore only used as examples, and cannot be used to limit the protection scope of the utility model.

[0028] See also Figure 1 In one embodiment, a tension test fixture for tissue engineering skin includes: a test device 1, a base 2, an electromagnetic pressure plate 3 and an adjustment mechanism 4.

[0029] In one implementation, the testing device 1 is disposed on a planar workbench, and includes: a sealed box 11 , a pressure sensor 14 , and a displacement sensor 15 .

[0030] Specifically, the sealed box 11 includes a box body, a door 12 and a base 13. In order to facilitate the observation of the changes of the tissue engineered skin 4 during the test, the sealed box 11 is made of a transparent plastic material. An opening 111 is provided on the side of the sealed box 11, and rubber pads are provided around the outside of the opening 111. The opening 111 is provided with a door 12 hinged to the transparent box 11; the door 12 rotates downward to cover the opening 111, and a sealing pad is installed on the inner side of the door 12. With this structure, the door 12 is covered, and the edge of the door 12 is pressed on the rubber pad, and the sealing pad is in close contact with the inner wall of the opening, thereby improving the sealing of the sealed box 11. The base 13 is fixedly installed in the sealed box 11. The sealed box 11 is connected to the external air pressure boosting equipment through the air pipe and the air pressure valve 8, and the air pressure change in the sealed box 11 is adjusted by the air pressure valve 8. The pressure sensor 14 is mounted on the outer side of the top of the sealed box 11, and the sensing port of the pressure sensor 14 extends in the sealed box 11. The pressure sensor 14 is used to monitor the air pressure applied to the tissue engineering skin 4 in real time. Two displacement sensors 15 are provided, one of which is mounted on the base 13, and the other is arranged at the lower end of the sensing port of the pressure sensor 14, and is used to monitor the displacement of the tissue engineering skin 4 in real time as the air pressure changes. The displacement sensor 15 and the pressure sensor 14 are electrically connected to the external computer 7, respectively, and the computer 7 records and processes the pressure data of the pressure sensor 14 and the displacement data of the tissue engineering skin 4 as the pressure changes.

[0031] See also Figure 2 In one embodiment, the base 2 is mounted on the base 13. In order to facilitate the positioning of the base 2, a positioning groove 131 for accommodating the base 2 is provided on the base 13. The tissue engineering skin 4 is placed on the upper end of the base 2. The center of the base 2 is provided with a first cavity 21 for suspending and testing the tissue engineering skin 4. The displacement sensor 15 mounted on the base 13 is nested in the first cavity 21.

[0032] Preferably, the base 2 is made of iron material. In order to prevent damage to the tissue-engineered skin 4, the first cavity 21 is provided with chamfers along the circumference.

[0033] In one embodiment, the electromagnetic pressure plate 3 is provided with a second cavity 31 for testing, the first cavity 21 and the second cavity 31 provide displacement space for the tissue engineering skin 4 as the air pressure changes, and another displacement sensor 15 is arranged on the second cavity 31. The electromagnetic pressure plate 3 is connected to the base 2 by magnetic adsorption. When the power is turned on, the electromagnetic pressure plate 3 is magnetic, and the iron base 2 is attracted to the electromagnetic pressure plate 3 through the tissue engineering skin 4, and the electromagnetic pressure plate 3 fixes the tissue engineering skin 4 on the base 2; when the power is turned off, the electromagnetic pressure plate 3 loses its magnetism, and the electromagnetic pressure plate 3 can be removed from the base 2. Preferably, in order to enable the electromagnetic pressure plate 3 to be demagnetized immediately when the power is turned off and not to crush the tissue engineering skin 4, the electromagnetic pressure plate 3 is made of soft iron.

[0034] In order to conveniently and quickly place the electromagnetic pressing plate 3 on the base 2, the base 2 is provided with a plurality of positioning posts 22, which are evenly spaced along the circumference, and the electromagnetic pressing plate 3 is provided with positioning holes 32 matching the positioning posts 22. In order to enhance the clamping effect of the electromagnetic pressing plate 3 on the tissue engineering skin 4, anti-slip grooves are provided on each end surface of the electromagnetic pressing plate 3, and the anti-slip grooves are provided when the electromagnetic pressing plate 3 is taken and placed, so as to enhance the friction between the hand and the electromagnetic pressing plate 3.

[0035] The base 2 and the electromagnetic pressing plate 3 form a fixing fixture for testing the tissue engineering skin 4 .

[0036] In one embodiment, the adjustment mechanism 5 adjusts the magnetic force of the electromagnetic pressure plate 3 on the base 2 .

[0037] Specifically, the existing technology is used to adjust the magnetic force adsorption of the electromagnetic pressure plate 3 to the base 2 through the adjustment mechanism 5. For example, the adjustment mechanism 5 is a sliding rheostat, one end of the sliding rheostat is electrically connected to the power supply 6, and the other end is electrically connected to the electromagnetic pressure plate 3. The power supply 6 is a DC power supply. By adjusting the sliding rheostat, the resistance value in the circuit is changed, and the current in the circuit is changed, thereby changing the magnetic force adsorption of the electromagnetic pressure plate 3 to the base 2. When in use, the current value is selected according to the tissue engineering skin 4. When the voltage at the two ends of the electromagnetic pressure plate 3 remains unchanged, the corresponding current value can be obtained by adjusting the sliding rheostat.

[0038] When in use, the base 2 with different diameters of the first cavity 21 and the corresponding electromagnetic pressure plate 3 can be selected according to the size of the tissue engineering skin 4, and the tissue engineering skin 4 can be placed on the first cavity 21 of the base 2, and the electromagnetic pressure plate 3 can be placed on the base 2 to initially press the tissue engineering skin 4. Open the box door 12, place the fixing fixture with the tissue engineering skin 4 on the base 13, turn on the DC power supply, adjust the sliding rheostat according to the size and thickness of the engineering skin 4, obtain the corresponding magnetic force, and fix the tissue engineering skin 4 in the fixing fixture. The displacement sensor 15 and the pressure sensor 14 are electrically connected to the external computer 7 respectively; the closed box 11 is connected to the external air pressure boosting equipment through the air pressure valve 8. Adjust the air pressure valve 8 to slowly compress the air in the closed box 11 to increase the pressure, so as to achieve the loading of the tissue engineering skin 4. The displacement data of the tissue engineering skin 4 with pressure changes collected by the displacement sensor 15 and the pressure data loaded by the tissue engineering skin 4 collected by the pressure sensor 14 are fed back to the computer 7 for recording and processing. When the tissue engineering skin 4 is broken, the test is terminated, and the tension can be obtained through the processing of the computer 7. The external air pressure boosting device and the DC power supply are turned off, the electromagnetic pressure plate 3 loses its magnetism, the box door 12 is opened, the fixing fixture is taken out, and the next tissue engineering skin 4 sample test is carried out.

[0039] Beneficial effects of the utility model:

[0040] The above-mentioned tension test fixture for tissue engineering skin has an adjustment mechanism 5 set in the electromagnetic pressure plate 3. During the test, the current in the circuit is changed according to the area and thickness of the tissue engineering skin 4, so as to obtain a suitable magnetic force of the electromagnetic pressure plate 3 on the base 2. At the same time, the electromagnetic pressure plate 3 is made of soft iron with anti-slip grooves, which can clamp the tissue engineering skin 4 more effectively and effectively prevent the tissue engineering skin 4 from breaking or falling off at the clamping point.

[0041] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and specification of the present invention.

Claims

1. A tension test fixture for tissue engineering skin, characterized in that: include: Test equipment; A base is installed in the test device, the tissue-engineered skin is placed on the upper end of the base, and a first cavity is provided in the center of the base for suspending and testing the tissue-engineered skin; An electromagnetic pressing plate, wherein the electromagnetic pressing plate is provided with a second cavity for testing, and the electromagnetic pressing plate is connected to the base by magnetic attraction, and during the adsorption, the electromagnetic pressing plate fixes the tissue-engineered skin on the base; and An adjusting mechanism is electrically connected to the electromagnetic pressure plate, and the adjusting mechanism adjusts the magnetic attraction force of the electromagnetic pressure plate on the base.

2. The tension test fixture for tissue engineering skin according to claim 1, characterized in that: The regulating mechanism is a sliding rheostat, and the electromagnetic pressure plate is electrically connected to a DC power supply via the sliding rheostat.

3. The tension test fixture for tissue engineering skin according to claim 2, characterized in that: The base is made of iron, and the electromagnetic pressure plate is made of soft iron.

4. The tension test fixture for tissue engineering skin according to claim 3, characterized in that: The base is provided with a plurality of positioning posts, and the positioning posts are evenly spaced along the circumferential direction. The electromagnetic pressure plate is provided with positioning holes matched with the positioning posts.

5. The tension test fixture for tissue engineering skin according to claim 3, characterized in that: Each end surface of the electromagnetic pressure plate is provided with anti-slip grooves.

6. The tension test fixture for tissue engineering skin according to claim 1, characterized in that: The testing device comprises: a sealed box, a pressure sensor and a displacement sensor; the base is placed in the sealed box, and the displacement sensor is installed in the sealed box; the pressure sensor is installed on the sealed box, and the sealed box is connected to an external air pressure boosting device and can adjust the air pressure.

7. The tension test fixture for tissue engineering skin according to claim 6, characterized in that: The sealed box is provided with a positioning groove for accommodating the base.

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