Multi-dimensional liquid chromatograph
By using sealing layers, threaded connections and limit buckles in a multidimensional liquid chromatograph, the problem of easy falling off and winding of the intake pipe is solved, and the stable connection and convenient disassembly of the intake pipe is achieved, which improves the detection efficiency and precision.
Patent Information
- Application Number
- CN202420738126.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-11
- Publication Date
- 2024-12-17
- Estimated Expiration
- 2034-04-11
AI Technical Summary
The intake pipes in existing multidimensional liquid chromatographs are prone to fall off and wrap, resulting in low detection efficiency and poor accuracy.
The fixed connection structure is adopted, including a sealing layer, threaded connection and limit buckle, to ensure a stable connection of the intake pipe and prevent wrapping through the design of the slide rail and support plate.
It effectively prevents the air intake pipe from falling off and wrapping, improves the practicality and accuracy of detection, and is convenient to disassemble.
Smart Images
Figure CN222189209U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of liquid chromatography, in particular to a multidimensional liquid chromatograph. Background Art
[0002] Since macromolecular impurities such as proteins contained in biological samples can easily interfere with the detection of small molecule compounds and easily cause pipeline blockage and varying degrees of degradation of the first-dimensional chromatographic column, multidimensional liquid chromatography technology can be used to solve this problem.
[0003] In the prior art, Chinese patent publication number CN215218693U discloses a single molecule multi-dimensional liquid chromatograph, including a first chromatographic pump for conveying a release agent, a second chromatographic pump for conveying a mobile phase, a first waste liquid pipeline, an analysis pipeline, a first multi-way valve and a second multi-way valve, a second waste liquid pipeline and two chromatographic columns, the second waste liquid pipeline is connected to a second waste liquid pool, the two chromatographic columns are respectively a first chromatographic column and a second chromatographic column, the first chromatographic column is arranged between any two ports of the first multi-way valve, the first chromatographic column is used for online solid phase extraction for bidirectional separation; the second chromatographic column is arranged between the first multi-way valve and the second multi-way valve, the second chromatographic column is used for online analysis; the injector of the first chromatographic pump, the second chromatographic pump and the first waste liquid pipeline are respectively connected to one of the ports of the first multi-way valve, and the second waste liquid pipeline and the analysis pipeline are distributed and connected to the second multi-way valve. The utility model has a simple structure and improves work efficiency and detection accuracy.
[0004] There are multiple air inlet pipes inside the multidimensional liquid chromatograph. When the air inlet pipes are not connected firmly, they are easy to fall off inside the multidimensional liquid chromatograph. At the same time, multiple air inlet pipes are entangled with each other, causing confusion that is difficult to sort out. Therefore, the above problems need to be improved. Utility Model Content
[0005] The utility model aims to provide a multi-dimensional liquid chromatograph, which has the effects of preventing pipelines from falling off and preventing pipelines from winding.
[0006] The above technical purpose of the utility model is achieved through the following technical solutions: a multidimensional liquid chromatograph, comprising a chromatograph, a first disc fixedly connected inside the chromatograph, an air inlet channel fixedly connected inside the first disc, a sealing layer fixedly connected inside the air inlet channel, an air inlet pipe inserted inside the air inlet channel, a second disc fixedly connected at one end of the air inlet pipe, a hose fixedly connected inside the air inlet pipe, a bolt threadedly connected inside the second disc, a threaded hole opened inside the first disc, the bolt extends to the inside of the threaded hole, a hinge fixedly installed at the edge of the chromatograph, the chromatograph is hinged with a support plate through the hinge, and the top of the support plate is fixedly connected with a limiting buckle.
[0007] By adopting the above technical scheme, when the air intake pipe is connected to the air intake channel inside the chromatograph, the staff will insert the air intake pipe into the inside of the air intake channel, and the gap between the air intake pipe and the air intake channel is sealed by the sealing layer. Then the support plate is opened, and the support plate is flipped around the hinge to be perpendicular to the chromatograph. Then the hose is clamped to the inside of the limit buckle. The limit buckle is arranged in the form of a linear array, so that each hose can be arranged separately, thereby preventing the hose from being entangled and causing confusion. When the air intake pipe extends to the inside of the air intake channel, the first disc and the second disc will be matched. At this time, the staff will extend the bolts through the threaded holes to the inside of the first disc and the second disc, so that the air intake pipe can be fixed inside the air intake channel and is not easy to fall off. The device fixes the air intake pipe, making the air intake pipe not easy to fall off and easy to disassemble. At the same time, the hose at the tail of the air intake pipe can be arranged separately to prevent the hose from being entangled and causing confusion, thereby improving the practicality during use.
[0008] The utility model is further configured as follows: there are multiple limit buckles, and the multiple limit buckles are divided into two groups.
[0009] By adopting the above technical solution, since there are two hoses, the multiple limit buckles are evenly divided into two rows.
[0010] The utility model is further configured as follows: a slide rail is fixedly connected to the inner side of the chromatograph, and a slider is slidably connected to the interior of the slide rail.
[0011] By adopting the above technical solution, the slider is slidably connected to the inside of the slide rail, so that the slider can move up and down inside the slide rail.
[0012] The utility model is further configured as follows: the outer sides of the sliding block and the supporting plate are fixedly connected with connecting pins, and the middle part of the connecting pins is sleeved with a connecting plate.
[0013] By adopting the above technical solution, the outer sides of the slider and the support plate are connected with connecting plates through connecting pins. When the support plate is opened, the connecting plate will drive the slider to slide inside the slide rail, thereby limiting the support plate.
[0014] The utility model is further configured as follows: a column is fixedly connected to the bottom of the support plate, and a supporting foot is rotatably connected to the bottom of the column.
[0015] By adopting the above technical solution, the supporting feet are in contact with the base surface, thereby being able to support the bottom of the support plate, so that the support plate has stability during operation.
[0016] The utility model is further configured as follows: an anti-skid pad is fixedly connected to the bottom of the support leg, and anti-skid particles are fixedly connected to the outside of the anti-skid pad.
[0017] By adopting the above technical solution, the anti-skid pad and anti-skid particles improve the friction and prevent the support foot from shifting.
[0018] The beneficial effects of the utility model are:
[0019] 1. The utility model, through the arrangement among the chromatograph, the first disc, the air inlet channel, the sealing layer, the air inlet pipe, the second disc, the hose, the bolts, the threaded holes, the hinge, the support plate and the limit buckle, when the air inlet pipe is connected to the air inlet channel inside the chromatograph, the staff inserts the air inlet pipe into the inside of the air inlet channel, the gap between the air inlet pipe and the air inlet channel is sealed by the sealing layer, then opens the support plate, turns the support plate around the hinge, turns the support plate to be perpendicular to the chromatograph, then clamps the hose into the inside of the limit buckle, and the limit buckle is arranged in the form of a linear array. , and each hose can be sorted, thereby preventing the hoses from being entangled and causing confusion. After the intake pipe extends to the inside of the intake channel, the first disc and the second disc will be matched. At this time, the staff will extend the bolts through the threaded holes to the inside of the first disc and the second disc, so that the intake pipe can be fixed inside the intake channel and is not easy to fall off. The device fixes the intake pipe, making it difficult for the intake pipe to fall off and easy to disassemble. At the same time, the hoses at the tail of the intake pipe can be sorted to prevent the hoses from being entangled and causing confusion, thereby improving the practicality during use.
[0020] 2. The utility model, through the arrangement among the slide rail, the slider, the connecting pin, the connecting plate, the column and the supporting foot, the slider is slidably connected to the inside of the slide rail, so that the slider can move up and down inside the slide rail, the outer sides of the slider and the support plate are connected with the connecting plate through the connecting pin, when the support plate is opened, the connecting plate will drive the slider to slide inside the slide rail, so as to limit the support plate, the supporting foot contacts the base surface, so as to support the bottom of the support plate, so that the support plate has stability during operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0022] Figure 1 This is a schematic diagram of the explosion structure of the utility model;
[0023] Figure 2 For this utility model Figure 1 The enlarged structural diagram at A in the middle;
[0024] Figure 3 This is a schematic diagram of the sealing layer structure of the utility model;
[0025] Figure 4 It is a side view structural diagram of the support plate of the utility model.
[0026] In the figure, 1, chromatograph; 2, first disc; 3, air inlet channel; 4, sealing layer; 5, air inlet pipe; 6, second disc; 7, hose; 8, bolt; 9, threaded hole; 10, hinge; 11, support plate; 12, limit buckle; 13, slide rail; 14, slider; 15, connecting pin; 16, connecting plate; 17, column; 18, support foot; 19, anti-slip pad. DETAILED DESCRIPTION
[0027] The technical solution of the utility model will be described clearly and completely below in conjunction with specific embodiments. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of them. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0028] Reference Figure 1-4A multidimensional liquid chromatograph comprises a chromatograph 1, wherein a first disc 2 is fixedly connected inside the chromatograph 1, an air inlet channel 3 is fixedly connected inside the first disc 2, a sealing layer 4 is fixedly connected inside the air inlet channel 3, an air inlet pipe 5 is inserted inside the air inlet channel 3, a second disc 6 is fixedly connected at one end of the air inlet pipe 5, a hose 7 is fixedly connected inside the air inlet pipe 5, a bolt 8 is threadedly connected inside the second disc 6, a threaded hole 9 is provided inside the first disc 2, the bolt 8 extends into the threaded hole 9, a hinge 10 is fixedly installed at the edge of the chromatograph 1, a support plate 11 is hingedly connected to the chromatograph 1 through the hinge 10, a limit buckle 12 is fixedly connected to the top of the support plate 11, and when the air inlet pipe 5 is connected to the air inlet of the chromatograph 1, a limit buckle 12 is fixedly connected to the top of the support plate 11. When the air is in the air channel 3, the staff inserts the air inlet pipe 5 into the interior of the air inlet channel 3, and the gap between the air inlet pipe 5 and the air inlet channel 3 is sealed by the sealing layer 4. Then the support plate 11 is opened, and the support plate 11 is flipped around the hinge 10, and the support plate 11 is flipped to be perpendicular to the chromatograph 1, and then the hose 7 is clamped to the inside of the limit buckle 12. The limit buckle 12 is arranged in the form of a linear array, so that each hose 7 can be arranged, thereby preventing the hose from being entangled and causing confusion. After the air inlet pipe 5 extends to the interior of the air inlet channel 3, the first disc 2 and the second disc 6 will be matched. At this time, the staff extends the bolt 8 through the threaded hole 9 to the inside of the first disc 2 and the second disc 6, so that the air inlet pipe 5 can be in the air inlet channel 3 is fixed inside and is not easy to fall off. The device fixes the air inlet pipe 5 so that the air inlet pipe 5 is not easy to fall off and is easy to disassemble. At the same time, the hose 7 at the tail of the air inlet pipe 5 can be divided into groups to prevent the hose 7 from being entangled and causing confusion, thereby improving the practicality during use. There are multiple limit buckles 12, and the multiple limit buckles 12 are evenly divided into two groups. Since there are two hoses 7, the multiple limit buckles 12 are evenly divided into two groups. The inner side of the chromatograph 1 is fixedly connected with a slide rail 13, and the inner side of the slide rail 13 is slidably connected with a slider 14. The slider 14 is slidably connected to the inside of the slide rail 13, so that the slider 14 can move up and down inside the slide rail 13, and the outer sides of the slider 14 and the support plate 11 are fixedly connected with a connecting pin 1 5. A connecting plate 16 is sleeved at the middle of the connecting pin 15. The outer sides of the slider 14 and the support plate 11 are sleeved with the connecting plate 16 through the connecting pin 15. When the support plate 11 is opened, the connecting plate 16 will drive the slider 14 to slide inside the slide rail 13, so as to limit the support plate 11. The bottom of the support plate 11 is fixedly connected with a column 17. The bottom of the column 17 is rotatably connected with a support foot 18. The support foot 18 contacts the base surface, so as to support the bottom of the support plate 11, so that the support plate 11 has stability during operation. The bottom of the support foot 18 is fixedly connected with an anti-skid pad 19. The outside of the anti-skid pad 19 is fixedly connected with anti-skid particles. The anti-skid pad 19 and the anti-skid particles increase the friction to prevent the support foot 18 from shifting.
[0029] In the present invention, when the air intake pipe 5 is connected to the air intake channel 3 inside the chromatograph 1, the staff inserts the air intake pipe 5 into the inside of the air intake channel 3, and the gap between the air intake pipe 5 and the air intake channel 3 is sealed by the sealing layer 4, and then the support plate 11 is opened, and the support plate 11 is flipped around the hinge 10, and the support plate 11 is flipped to be perpendicular to the chromatograph 1, and then the hose 7 is clamped to the inside of the limiting buckle 12, and the limiting buckle 12 is arranged in the form of a linear array, so that each hose 7 can be arranged, thereby preventing the hose from being entangled and causing confusion. After the air intake pipe 5 extends to the inside of the air intake channel 3, the first disc 2 and the second disc 6 will be matched. At this time, the staff extends the bolt 8 through the threaded hole 9 to the inside of the first disc 2 and the second disc 6, so that the air intake pipe 5 can be The air intake passage 3 is fixed inside and is not easy to fall off. The device fixes the air intake pipe 5, so that the air intake pipe 5 is not easy to fall off and is easy to disassemble. At the same time, the hose 7 at the tail of the air intake pipe 5 can be arranged to prevent the hose 7 from being entangled and causing confusion, thereby improving the practicality during use. The slider 14 is slidably connected to the inside of the slide rail 13, so that the slider 14 can move up and down inside the slide rail 13. The outer sides of the slider 14 and the support plate 11 are both connected with a connecting plate 16 through a connecting pin 15. When the support plate 11 is opened, the connecting plate 16 will drive the slider 14 to slide inside the slide rail 13, so that the support plate 11 can be limited. The support foot 18 contacts the base surface, so as to support the bottom of the support plate 11, so that the support plate 11 is stable during operation.
[0030] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A multidimensional liquid chromatograph, comprising a chromatograph (1), characterized in that: The interior of the chromatograph (1) is fixedly connected with a first disc (2), the interior of the first disc (2) is fixedly connected with an air inlet passage (3), the interior of the air inlet passage (3) is fixedly connected with a sealing layer (4), the interior of the air inlet passage (3) is plugged with an air inlet pipe (5), one end of the air inlet pipe (5) is fixedly connected with a second disc (6), the interior of the air inlet pipe (5) is fixedly connected with a hose (7), the interior of the second disc (6) is threadedly connected with a bolt (8), the interior of the first disc (2) is provided with a threaded hole (9), the bolt (8) extends into the interior of the threaded hole (9), a hinge (10) is fixedly installed at the edge of the chromatograph (1), the chromatograph (1) is hinged with a support plate (11) via the hinge (10), and the top of the support plate (11) is fixedly connected with a limit buckle (12).
2. A multidimensional liquid chromatograph according to claim 1, characterized in that: The number of the limiting buckles (12) is multiple, and the multiple limiting buckles (12) are divided into two groups.
3. A multidimensional liquid chromatograph according to claim 1, characterized in that: A slide rail (13) is fixedly connected to the inner side of the chromatograph (1), and a slider (14) is slidably connected to the interior of the slide rail (13).
4. A multidimensional liquid chromatograph according to claim 3, characterized in that: The outer sides of the sliding block (14) and the supporting plate (11) are fixedly connected with a connecting pin (15), and the middle part of the connecting pin (15) is sleeved with a connecting plate (16).
5. A multidimensional liquid chromatograph according to claim 1, characterized in that: The bottom of the support plate (11) is fixedly connected to a column (17), and the bottom of the column (17) is rotatably connected to a support foot (18).
6. A multidimensional liquid chromatograph according to claim 5, characterized in that: The bottom of the support foot (18) is fixedly connected to an anti-skid pad (19), and the outside of the anti-skid pad (19) is fixedly connected to anti-skid particles.